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Clinical trials published in the Boletín Médico del Hospital Infantil de México: a critical analysis 临床试验发表在Boletín msamadico del Hospital infant de msamadico:批判性分析
Pub Date : 2019-01-29 DOI: 10.24875/bmhime.m18000044
Leticia A Barajas-Nava, Andrea Sandoval-Campos, Karen A. Aguirre-Raya
Background: Controlled clinical trials (CCT) are the study design with the highest accuracy and evidence level. From its introduction in biomedical research, changes have been implemented in the way of establishing the basis for diagnosis, prognosis and treatment in clinical practice. Studies to identify published CCTs regarding different medical fields have been carried out. To date, none of them has identified the clinical trials that have been published in the Boletín Médico del Hospital Infantil de México (BMHIM). The aim of this study was to identify and describe the controlled clinical trials published in
背景:对照临床试验(CCT)是准确度和证据水平最高的研究设计。自引入生物医学研究以来,在临床实践中建立诊断、预后和治疗依据的方式发生了变化。针对不同医学领域已发表的cct进行了研究。迄今为止,他们都没有确定在Boletín《 )》上发表的临床试验。本研究的目的是识别和描述发表在
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引用次数: 0
Screening of adverse childhood experiences in preschoolers: a systematic review 筛选学龄前儿童不良童年经历:一项系统综述
Pub Date : 2019-01-29 DOI: 10.24875/BMHIME.M17000010
Maribel Vega-Arce, Gastón Núñez-Ulloa
The present review aims to describe scientific publications available that detail strategies and screening tools for adverse childhood experiences in preschoolers (2 to 5 years of age). A systematic review of the topic was carried out through research articles published in peer-reviewed journals from January 1998 to June 2017 and indexed in seven international databases (Cochrane Library, EBSCO, PubMed, Science Direct, Springer, Web of Science and Scielo). The articles were selected based on predefined criteria, using limiters and manual screening. Twenty articles published between 1999 and 2017 were selected. The screening of adverse childhood experiences is performed through opportunistic recruitment in a professional context aimed at caregivers and children, which integrates training actions, application of screening tools, and reception of identified cases. Screening tools differ between interviews and questionnaires. In addition, we report the periodicity of the screening, the behaviors, and beliefs of the professionals against it and the barriers to its implementation. This review confirms that the screening of adverse childhood experiences is an emerging topic in the research field. We emphasize the need to systematize and evaluate the strategies and tools for screening adverse childhood experiences, as well as to develop local approaches to respond to the needs of children exposed to adversity.
本综述旨在描述现有的科学出版物,这些出版物详细介绍了学龄前儿童(2至5岁)不良童年经历的策略和筛查工具。通过1998年1月至2017年6月在同行评议期刊上发表的研究文章,并在七个国际数据库(Cochrane Library、EBSCO、PubMed、Science Direct、施普林格、Web of Science和Scielo)中检索,对该主题进行了系统综述。文章的选择是基于预定义的标准,使用限制和人工筛选。选取了1999年至2017年间发表的20篇文章。儿童不良经历的筛查是通过在专业背景下针对照顾者和儿童的机会性招募进行的,其中包括培训行动、筛查工具的应用和已确定病例的接收。面试和问卷的筛选工具有所不同。此外,我们还报告了筛查的周期性、专业人员反对筛查的行为和信念以及实施筛查的障碍。这篇综述证实了不良童年经历的筛选是一个新兴的研究领域。我们强调需要系统化和评估筛选不良童年经历的策略和工具,并制定当地方法来应对面临逆境的儿童的需求。
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引用次数: 0
Medical arbitration and claims for malpractice related to health service users under 15 years of age during 2011-2015 2011-2015年期间与15岁以下保健服务使用者有关的医疗仲裁和医疗事故索赔
Pub Date : 2019-01-29 DOI: 10.24875/bmhime.m18000038
S. Fernández-Cantón, J. N. Rizo-Amézquita
Background: Claims by health services users are a negative indicator of the care quality. To know the situations that origi-nate them and their consequences are key issues to consider in order to design strategies to improve the quality of health-services. This study analyzes the cases submitted to the National Medical Arbitration Commission with a final arbitration decision during the period 2011-2015, related to health service users younger than 15 years old. Methods: This was a cross-sectional descriptive study. We analyzed information extracted from the reports with a final arbitration decision in the past 5 years, selecting those where the affected users were younger than 15 years old. Results : A total of 40 case arbitral awards were found, most of them involving pediatric services with a similar number of male and female users and a similar proportion in the extreme age groups, <1 year (32%) and 10-14 years (30%). The main cause of the complaint was related to diagnostic procedures (45%). An average of 8.7 adverse events per case was identified, most of them associated with procedures. Among the damages, there were 12 deaths and 9 permanent disabilities. There was evidence of malpractice in 65% of the cases and the sentence was condemnatory in 60% of the cases. Conclusions: This manuscript shows information in four main sections: sociodemographic characteristics, description of medical care, adverse events and their repercus-sions on health damages, evaluation of the medical act, and conclusions of the arbitration process.
背景:保健服务使用者的索赔是保健质量的一个负面指标。了解造成这些问题的情况及其后果是制定改善保健服务质量战略所要考虑的关键问题。本研究分析了2011-2015年期间提交国家医疗仲裁委员会并作出最终仲裁决定的与15岁以下卫生服务使用者相关的案件。方法:采用横断面描述性研究。我们分析了过去5年中从最终仲裁决定的报告中提取的信息,选择了受影响用户年龄小于15岁的报告。结果:共发现40例仲裁裁决,其中大多数涉及儿童服务,男女用户数量相似,极端年龄组比例相似,<1岁(32%)和10-14岁(30%)。投诉的主要原因与诊断程序有关(45%)。平均每例8.7个不良事件被确定,其中大多数与手术有关。在这些损失中,有12人死亡,9人终身残疾。65%的案件有渎职证据,60%的案件被判有罪。结论:该手稿显示了四个主要部分的信息:社会人口特征、医疗保健描述、不良事件及其对健康损害的影响、医疗行为的评估和仲裁过程的结论。
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引用次数: 0
Pulmonary sequestration associated with congenital pulmonary airway malformation 肺隔离与先天性肺气道畸形的关系
Pub Date : 2019-01-29 DOI: 10.24875/bmhime.m18000031
Z. A. D. León-Ureña, S. Sadowinski-Pine, Lourdes Jamaica-Balderas, J. Penchyna-Grub
Background: Congenital pulmonary malformations are a rare cause of neonatal morbidity. Some of them have a common origin, which allows the identification of combined lesions. Its diagnosis can be made prenatally by ultrasound, with the limitation that this study is performed in specialized centers and depends on the expertise of the operator. The association of pulmonary sequestration and congenital malformation of the airway has been described in approximately 40-60 cases since its first description in 1949. Many lesions are not perceptible in intrauterine life, and in the neonatal period, there are recurrent respiratory symptoms that in some cases are associated with a congenital pulmonary malformation. case report: We report the case of a young infant, who was diagnosed with pulmonary sequestration at 24 weeks of gestational age, undergoing intrauterine surgical treatment with a report of complete resolution of the malformation in posterior ultrasounds. She was valued by pediatric pneumology at four months of age, where angiotomography was performed, and the presence of pulmonary sequestration was confirmed by lobectomy. The histopathological study reported extralobar pulmonary sequestration with congenital malformation of the pulmonary airway type 2. The histopathological study identified these combined lesions. The treatment of choice was surgical. conclusions: Upon the confirmation of a malformation, we emphasize the importance of performing screening to search for other that could be associated.
背景:先天性肺畸形是一种罕见的新生儿发病原因。其中一些有一个共同的起源,这允许识别合并病变。它的诊断可以通过产前超声进行,但局限性在于这项研究是在专门的中心进行的,并且取决于操作者的专业知识。自1949年首次描述以来,肺隔离与先天性气道畸形的关联已在大约40-60例中被描述。许多病变在宫内生活中不易察觉,在新生儿时期,有反复出现的呼吸道症状,在某些情况下与先天性肺畸形有关。病例报告:我们报告的情况下,年轻的婴儿,谁被诊断为肺隔离在24周孕龄,接受宫内手术治疗的报告完全解决畸形后超声。她在4个月大时接受了儿科肺病检查,并进行了血管断层扫描,肺叶切除术证实了肺隔离的存在。组织病理学研究报告了先天性2型气道畸形的肺叶外肺隔离。组织病理学研究确定了这些合并病变。治疗的选择是手术。结论:在确认畸形后,我们强调进行筛查以寻找其他可能相关的畸形的重要性。
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引用次数: 2
Urinary tract infections, immunity, and vaccination 尿路感染,免疫和疫苗接种
Pub Date : 2019-01-29 DOI: 10.24875/bmhime.m18000025
V. Luna-Pineda, Sara A. Ochoa, Ariadnna Cruz-Córdova, Vicenta Cázares-Domínguez, Fernanda Vélez-González, R. Hernández-Castro, J. Xicohtencatl-Cortes
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引用次数: 1
Fever and antipyretic therapy in the septic patient in the intensive care unit: an update 重症监护室脓毒症患者的发热和退热治疗:最新进展
Pub Date : 2019-01-29 DOI: 10.24875/bmhime.m18000039
A. Donoso, D. Arriaga
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引用次数: 3
Shock index utility to predict mortality in pediatric patients with septic shock or severe sepsis 休克指数用于预测感染性休克或严重脓毒症患儿的死亡率
Pub Date : 2019-01-29 DOI: 10.24875/BMHIME.M18000041
Claudia S. López-Reyes, Lilia N. Baca-Velázquez, M. Villasís-Keever, J. Zurita-Cruz
Background: Pediatric sepsis is considered the main cause of hospital death around the world. Many groups have tried to create tools that facilitate its early identification, as the shock index (SI), defined as the ratio between cardiac frequency and systolic blood pressure. The objective of this study was to determine the utility of SI to predict mortality in pediatric patients with severe sepsis and septic shock. Methods: A retrospective cohort study with 165 pediatric patients with severe sepsis or septic shock in the Pediatric Intensive Care Unit. SI was calculated at diagnosis and at 2, 4, and 6 h after (SI2, SI4, and SI6). We divided the population into two groups depending on their outcome: survivors and non-survivors. The statistical analysis was performed with Mann–Whitney U-test and Chi-squared tests. The risk factors were compared between the survivors and the dead, and we calculated the odds ratio (OR). Results: The median value of SI was compared between groups; in the group of septic shock, SI showed a tendency to remain high in SI4 and SI6 (p = 0.010 and p = 0.005, respectively). Among the survivors and the non-survivors, we found that in the latter, SI was progressively increased in SI4 and SI6 (p < 0.05). High values of SI4 and SI6 increased the risk of death in patients (SI4: OR = 442.1 confidence interval [CI] 95% 54.2-3601.7, p < 0.001 and SI6: OR = 81951.3 CI 95% 427.1-15700000, p < 0.001). conclusions: High values of SI are associated with increased mortality. The IS6 value is the most useful to predict mortality.
背景:儿童败血症被认为是世界范围内医院死亡的主要原因。许多研究小组试图创造工具来促进早期识别,如休克指数(SI),定义为心脏频率与收缩压之间的比率。本研究的目的是确定SI在预测严重脓毒症和感染性休克患儿死亡率中的应用。方法:回顾性队列研究165例重症监护室严重脓毒症或感染性休克患儿。在诊断时和诊断后2、4和6小时计算SI (SI2、SI4和SI6)。我们根据结果将人群分为两组:幸存者和非幸存者。统计学分析采用Mann-Whitney u检验和卡方检验。比较生存者和死亡者的危险因素,计算比值比(OR)。结果:组间比较SI中位数;脓毒性休克组SI4、SI6 SI仍有较高的趋势(p = 0.010、p = 0.005)。在幸存者和非幸存者中,我们发现后者SI4和SI6的SI逐渐升高(p < 0.05)。SI4和SI6的高值增加了患者的死亡风险(SI4: OR = 442.1可信区间[CI] 95% 54.2-3601.7, p < 0.001; SI6: OR = 81951.3可信区间[CI] 95% 427.1-15700000, p < 0.001)。结论:高SI值与死亡率增加有关。IS6值对预测死亡率最有用。
{"title":"Shock index utility to predict mortality in pediatric patients with septic shock or severe sepsis","authors":"Claudia S. López-Reyes, Lilia N. Baca-Velázquez, M. Villasís-Keever, J. Zurita-Cruz","doi":"10.24875/BMHIME.M18000041","DOIUrl":"https://doi.org/10.24875/BMHIME.M18000041","url":null,"abstract":"Background: Pediatric sepsis is considered the main cause of hospital death around the world. Many groups have tried to create tools that facilitate its early identification, as the shock index (SI), defined as the ratio between cardiac frequency and systolic blood pressure. The objective of this study was to determine the utility of SI to predict mortality in pediatric patients with severe sepsis and septic shock. Methods: A retrospective cohort study with 165 pediatric patients with severe sepsis or septic shock in the Pediatric Intensive Care Unit. SI was calculated at diagnosis and at 2, 4, and 6 h after (SI2, SI4, and SI6). We divided the population into two groups depending on their outcome: survivors and non-survivors. The statistical analysis was performed with Mann–Whitney U-test and Chi-squared tests. The risk factors were compared between the survivors and the dead, and we calculated the odds ratio (OR). Results: The median value of SI was compared between groups; in the group of septic shock, SI showed a tendency to remain high in SI4 and SI6 (p = 0.010 and p = 0.005, respectively). Among the survivors and the non-survivors, we found that in the latter, SI was progressively increased in SI4 and SI6 (p < 0.05). High values of SI4 and SI6 increased the risk of death in patients (SI4: OR = 442.1 confidence interval [CI] 95% 54.2-3601.7, p < 0.001 and SI6: OR = 81951.3 CI 95% 427.1-15700000, p < 0.001). conclusions: High values of SI are associated with increased mortality. The IS6 value is the most useful to predict mortality.","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"316 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91314185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Evaluation of the Boletín Médico del Hospital Infantil de México by the Literature Selection Technical Review Committee of the National Library of Medicine 国家医学图书馆文献选择技术审查委员会对Boletín msamadico del Hospital Infantil de msamadico的评价
Pub Date : 2019-01-29 DOI: 10.24875/BMHIME.M18000017
M. Campos-Lara
Correspondence: *María Guadalupe Campos-Lara Email: bolmedhospinfantmex@gmail.com Available online: 12-07-2018 Bol Med Hosp Infant Mex. 2018;75:5-6 www.bmhim.com Date of reception: 29-01-2018 Date of acceptance: 30-01-2018 DOI: 10.24875/BMHIME.M18000017 Evaluate ...evaluate... Evaluation, among other definitions, means to “collect and systematically analyze information to determine the value or merit of what is done”. To evaluate all human activity is inherent to the very nature of man. Governments, health, education, arts, institutions, organizations, companies are evaluated, and of course, the scientific activity of researchers, their projects, their papers, their “productivity” and even the journals where they publish their results. Why? What? How? On November 7, 2017, an email to the Boletín Médico del Hospital Infantil de México (BMHIM) arrived, with an attached letter from the Associate Director of Operations of the National Library of Medicine of the United States with the subject BMHIM, in which the first paragraph said: “The National Library of Medicine (NLM) uses an NIH-chartered advisory committee, the Literature Selection Technical Review Committee (LSTRC), to recommend journals to be indexed for MEDLINE®. At the recent LSTRC meeting, the committee recommended your journal for MEDLINE®. MEDLINE® citations are indexed with NLM Medical Subject Headings (MeSH®) and other metadata, and are searchable as a subset of PubMed®.” First, joy. Great joy! The gap opened in December 1993, the last time that BMHIM appeared in MEDLINE, was finally closed. Next, great news to the authorities of our institute, and to the personnel of the Medical Editions Department ...Immediately after, acknowledgement; later, reflection... Acknowledgements to the authors who, since July 2014, and before, have sent their research to our journal. To the reviewers, who made possible one the main pillars of academic journals with their voluntary and professional work: the evaluation of the scientific content by external colleagues and peers of the field in question. To the members of the board and editorial committee that have collaborated with the BMHIM. To the authorities of the Hospital Infantil de México Federico Gómez, who have unconditionally supported the development of BMHIM. To the translators. To the editors. To the publishers that have believed in our work. Reflections ...It is worth mentioning the following: what did the LSTRC evaluate from our journal? Strict compliance with the periodicity of the publication of the Spanish electronic version (ISSN 1665-1146), also available in English; the quality of the content of the articles including authors and institutions; the quality of the external peer review. Furthermore, that all ethical policies were met: declaration of conflicts of interest, animal and human rights, and informed consent when appropriate.
通讯:*María Guadalupe Campos-Lara Email: bolmedhospinfantmex@gmail.com在线出版:12-07-2018 Bol Med hospital Infant Mex. 2018;75:5-6 www.bmhim.com接收日期:29-01-2018接收日期:30-01-2018 DOI: 10.24875/BMHIME。M18000017求…求…在其他定义中,评估意味着“收集和系统地分析信息,以确定所做工作的价值或优点”。评价一切人类活动是人的本性所固有的。政府、卫生、教育、艺术、机构、组织、公司都被评估,当然,还有研究人员的科学活动、他们的项目、他们的论文、他们的“生产力”,甚至是他们发表研究结果的期刊。为什么?怎么啦?如何?2017年11月7日,我们收到了一封电子邮件,邮件的主题是BMHIM,收件人是美国国家医学图书馆运营副主任,邮件第一段写道:“美国国家医学图书馆(NLM)使用nih特许的咨询委员会,文献选择技术审查委员会(LSTRC),来推荐MEDLINE®索引的期刊。在最近的LSTRC会议上,委员会推荐您的期刊进入MEDLINE®。MEDLINE®引文用NLM医学主题标题(MeSH®)和其他元数据编入索引,并可作为PubMed®的子集进行搜索。”首先,快乐。好快乐!1993年12月,BMHIM最后一次出现在MEDLINE上,这一差距终于被弥合了。接下来,有个好消息要告诉我们研究所的领导,以及医学编辑部的工作人员……紧接着,确认;之后,反思……感谢自2014年7月及之前向本刊投稿的作者。感谢审稿人,他们以自愿和专业的工作使学术期刊的主要支柱之一成为可能:由相关领域的外部同事和同行对科学内容进行评估。与BMHIM合作的董事会和编辑委员会成员。感谢米姆希科·费德里科婴儿医院Gómez的主管部门,他们无条件地支持米姆希科医院的发展。致翻译。致编辑。感谢那些信任我们工作的出版商。反思……值得一提的是:LSTRC从我们的期刊中评价了什么?严格遵守出版周期的西班牙文电子版本(ISSN 1665-1146),同时提供英文版本;文章内容的质量,包括作者和机构;外部同行评审的质量。此外,所有伦理政策都得到满足:声明利益冲突,动物和人权,并在适当的情况下知情同意。
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引用次数: 0
Risk factors related to cardiovascular complications in children diagnosed with Kawasaki disease in Northwestern Mexico 墨西哥西北部诊断为川崎病儿童心血管并发症的相关危险因素
Pub Date : 2019-01-29 DOI: 10.24875/bmhime.m18000033
O. A. Flores-Montes, J. Valle-Leal, Roberto Arreguín-Reyes, Jesús M. Armenta-Velderrain
Kawasaki disease (KD) is an acute systemic vasculitis of small and medium vessels, which occurs primarily in children; it manifests itself as a febrile syndrome coupled with vasculitis data and can cause coronary artery abnormalities in 25% of untreated patients. The objective of this study was to describe the clinical behavior and to identify risk factors for cardiovascular complications in pediatric patients with KD, in a second level hospital in Northwestern Mexico.Under a case series design, we studied pediatric patients with diagnosis of KD. We measured clinical variables, laboratory values and the presence of cardiac complications; the probability of risk was determined with odds ratio (OR) and the association with chi squared test.12 patients were included, and the female gender predominated; the mean age of presentation of KD was 2 years. The clinical presentation was complete in 100 % of the cases and patients also presented atypical manifestations. 50% of the patients studied had cardiovascular complications, the most common of which was coronary disease (33%). The variables male gender, age under 2 years and anemia reported OR of 5.5 and 10 to present cardiovascular complications.Cardiovascular complications of KD are frequent (more than 30%). Male gender, age under 2 years and anemia increase the probability of risk for the presence of cardiovascular complications.
川崎病(Kawasaki disease, KD)是一种主要发生于儿童的中小型血管的急性全身性血管炎;它表现为伴有血管炎的发热综合征,在25%未经治疗的患者中可导致冠状动脉异常。本研究的目的是描述临床行为,并确定心血管并发症的危险因素在儿童KD患者在墨西哥西北部的二级医院。在病例系列设计下,我们研究了诊断为KD的儿科患者。我们测量了临床变量、实验室值和心脏并发症的存在;采用比值比(OR)和卡方检验确定风险发生概率。纳入12例患者,以女性为主;KD的平均发病年龄为2岁。100%的病例临床表现完整,患者也有不典型表现。50%的患者有心血管并发症,其中最常见的是冠状动脉疾病(33%)。男性、2岁以下年龄和贫血的OR分别为5.5和10。KD的心血管并发症较多(30%以上)。男性、年龄在2岁以下和贫血会增加心血管并发症发生的风险。
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引用次数: 2
Prevalence of exclusive breastfeeding in the healthy newborn 健康新生儿纯母乳喂养的普及程度
Pub Date : 2019-01-29 DOI: 10.24875/bmhime.m18000024
Pedro Luis del Mazo-Tomé, Marta Suárez-Rodríguez
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引用次数: 0
期刊
Boletín Médico Del Hospital Infantil de México (English Edition)
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