Boletín Médico Del Hospital Infantil de México (English Edition)最新文献

{"title":"Evaluation of recurrence of musculoskeletal tumors with thallium-201 scintigraphy plus SPECT/CT in a pediatric population","authors":"S. Medina-Ornelas, Herlinda Vera-Hermosillo, Rafael Delgado-Espín, F. García-Pérez","doi":"10.24875/bmhime.m18000022","DOIUrl":"https://doi.org/10.24875/bmhime.m18000022","url":null,"abstract":"Imaging studies, particularly simple and contrast-enhanced tomography, constitute the first diagnostic approach to detect recurrence of musculoskeletal tumors. The aim of the present retrospective study was to demonstrate the usefulness of scintigraphy plus SPECT/CT (single photon emission computed tomography) with thallium-201 (201Tl) in the evaluation of malignant musculoskeletal tumors with suspicion of recurrence or metastatic disease.Eight weeks after the last therapy, 72 scintigraphy and SPECT/CT studies were performed to assess regional recurrence and metastatic disease in 42 patients with different types of malignant musculoskeletal tumors, such as osteosarcoma, Ewing's sarcoma, rhabdomyosarcoma, retinoblastoma, synovial sarcoma, and Wilms tumor at the Hospital Infantil de Mexico Federico Gomez. The positive predictive value (PPV) and the confidence interval of the scintigraphy and SPECT/CT were calculated when compared with the results of the histopathological analysis and the clinical and radiological follow-up for the identification of recurrence.Scintigraphy was abnormal in 30 (71.4%) of the 42 patients; 33 lesions (30 patients) were detected by scintigraphy and 25 lesions (21 patients) by chest X-ray and tomography of two regions. The SPECT/CT was performed on 30 patients, where 12 lesions were detected in addition to the planar scintigraphy. Scintigraphy showed a PPV of 82%; SPECT/CT, 100%.201Tl-scintigraphy can be considered as an adequate study to identify the sites of tumor viability with a high degree of diagnostic certainty combined with the SPECT/CT technique.","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77761933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facing a new generation of hospital pathogens in Pediatrics","authors":"Guillermo Francisco Rosales-Magallanes","doi":"10.24875/bmhime.m17000009","DOIUrl":"https://doi.org/10.24875/bmhime.m17000009","url":null,"abstract":"Correspondence: *Guillermo F. Rosales Magallanes E-mail: dr_gmagal76@hotmail.com Available online: 18-06-2018 Bol Med Hosp Infant Mex. 2017;74:381-382 www.bmhim.com Received: 11-07-2017 Accepted: 17-07-2017 DOI: 10.24875/BMHIME.M17000009 Health-care related infections have a direct impact on the course and prognosis of every patient since they translate into prolonged lengths of stay and clinical worsening. Prolonged lengths of stay increase expenses in every medical unit because human and material resources are used every day. According to the World Health Organization, every nosocomial infection is preventable and treatable. Attention is focused on the processes that affect the clinical course of any patient, especially those in a vulnerable age group: the pediatric age. Current advances in medicine have stood out for dealing with highly lethal invasive bacteria with an increasingly peculiar resistance profile. To face this generation of pathogens, the pediatrician is obliged to be aware of the epidemiology of every hospital unit, which should be updated at least every six months by the Infectology services of every unit (committees for the prevention and control of nosocomial infections) or by the hospital epidemiology service. Results should be displayed in clinical areas, given the variability in sensitivity patterns and constant resistance because of the indiscriminate use of antibiotics. Therefore, management rules for healthcare related infections should be developed in every unit, along with management guidelines that should be respected. Even though microbial versatility related to resistance is currently being faced, every disease should be managed according to existing sensitivities to predict the next step in bacterial mutation. Punctual knowledge of the phenotype (which, at least, helps to understand the diverse intrinsic mechanisms that bacteria possess) allows being one step ahead of these increasingly complicated-to-treat pathogens. It is the obligation and responsibility of the committees to offer updated guidelines every six months and start a program for rational use of antibiotics with a blockade of antibiotics that induce cross-resistance. However, what about those who defend normativity or those who rise in defense of clinical practice guidelines? While these tools help to make decisions, they can be useful as long as knowledge of the predominant microbiota and resistance is considered. All these guidelines include a legend that states “as long as your hospital unit is not overwhelmed by resistance”. Therefore, guidelines can provide guidance but not always point to the right path, especially with the certainty that their proposal is not useful due to resistance. Occasionally, the fear of using “forbidden” antibiotics in pediatrics (quinolones, tetracycline before eight years of age) prevails. We have been taught “first, do no harm”. Nevertheless, microorganisms have surpassed us. They have become more difficult to treat: E","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73912236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between homozygous c.318A>GT mutation in exon 2 of the EIF2B5 gene and the infantile form of vanishing white matter leukoencephalopathy","authors":"C. Esmer, Gabriela Blanco-Hernández, V. Saavedra-Alanis, J. Reyes-Vaca, A. Bravo-Oro","doi":"10.24875/bmhime.m17000007","DOIUrl":"https://doi.org/10.24875/bmhime.m17000007","url":null,"abstract":"","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75171009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal prenatal history and neonatal risk complications for low-weight for gestational age term newborns","authors":"Karina L. Arce-López, Juan Vicencio-Rivas, José Iglesias-Leboreiro, Isabel Bernárdez-Zapata, Mario Enrique Rendón-Macías, Ariela Braverman-Bronstein","doi":"10.24875/BMHIME.M18000043","DOIUrl":"https://doi.org/10.24875/BMHIME.M18000043","url":null,"abstract":"","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"192 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79618748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal employment and Mexican school-age children overweight in 2012: the importance of household features","authors":"Alejandro Martínez Espinosa","doi":"10.24875/bmhime.m18000029","DOIUrl":"https://doi.org/10.24875/bmhime.m18000029","url":null,"abstract":"Background: International evidence regarding the relationship between maternal employment and school-age children overweight and obesity show divergent results. In Mexico, this relationship has not been confirmed by national data sets analysis. Consequently, the objective of this article was to evaluate the role of the mothers’ participation in labor force related to excess body weight in Mexican school-age children (age 5-11 years). Methods: A cross-sectional study was conducted on a sample of 17,418 individuals from the National Health and Nutrition Survey 2012, applying binomial logistic regression models. Results: After controlling for individual, maternal and contextual features, the mothers’ participation in the labor force was associated with children body composition. However, when the household features (living arrangements, household ethnicity, size, food security and socioeconomic status) were incorporated, maternal employment was no longer statistically significant. conclusions: Household features are crucial factors for understanding the overweight and obesity prevalence levels in Mexican school-age children, despite the mother having a paid job.","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74610285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Archibald Cochrane: evidence, effectiveness and decision-making in health","authors":"Arantxa Fátima Hortiales-González, Jorge Antonio Gómez-Navarro, Leticia A Barajas-Nava, J. Garduño-Espinosa","doi":"10.24875/BMHIME.M17000001","DOIUrl":"https://doi.org/10.24875/BMHIME.M17000001","url":null,"abstract":"Currently, Evidence-Based Medicine plays a fundamental role while making medical decisions, considering that through the methods of science it attempts to justify the variety of alternatives that may be offered to patients. In order to understand the historical evolution of this way of practicing medicine, it is necessary to review the contribution of one of the main participants in this cultural movement: Archibald Leman Cochrane, who helped to define the theoretical framework that has allowed the integration of science into the practice of medicine. Since he insisted on the need of integrating scientific evidence into the clinical experience, his role became a fundamental and decisive element in the development of a new discipline: Eviden-","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"86 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73673137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proteomic analysis of the excretion-secretion products of four Trichinella spiralis isolates obtained from accidental hosts","authors":"L. Franco-Sandoval, E. Jiménez-Cardoso, Héctor Quezada-Pablo, A. Guzmán-Ortiz","doi":"10.24875/bmhime.m17000015","DOIUrl":"https://doi.org/10.24875/bmhime.m17000015","url":null,"abstract":"","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87433998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reductionism in medicine","authors":"P. Young, P. Justich","doi":"10.24875/BMHIME.M18000046","DOIUrl":"https://doi.org/10.24875/BMHIME.M18000046","url":null,"abstract":"correspondence: *Pablo Young E-mail: pabloyoung2003@yahoo.com.ar Available online: 23-11-2018 Bol Med Hosp Infant Mex. 2018;75:227-229 www.bmhim.com Date of reception: 19-04-2018 Date of acceptance: 15-05-2018 DOI: 10.24875/BMHIME.M18000046 We have read carefully the work of the Biologist Juan Emilio Sala published in the Boletín Médico del Hospital Infantil de México1. We agree with the author that complex thinking and holistic vision are superior to the pure reductionist look. We have found the contribution of both clinical cases as a clarifying mean to convey his idea. The author sets out in the first paragraphs that he intends to generate a debate in the ways of thinking of pediatricians and physicians. To us, he has generated it, so he has fulfilled his purpose. Although there are things which it is difficult to agree on, the debate raised through the argumentation opens the horizon for further improvement. In general terms, we observe a complete and complex analysis in line with what the topic deserves. We also believe, even from dissimilar ideological perspectives, that the first part of the article, based on very appealing sociological instruments, proposes an almost causal relation between the evolution of Adam Smith’s division of labor and the evolution of medicine. It seems to us more as a demonstration of the ontological reductionism that is being questioned in the article than a proof of a broad vision of a multifactorial, dynamic, and transversal phenomenon such as the thinking evolution in medicine. We can share or discuss the effects produced by the bourgeoisie or neoliberalism on the models of attention or in certain partial behavioral imprinting, but the generalization toward the complex thought of our art/science has very limited value. This simplification can lead us to insufficiently well-founded conclusions. Undoubtedly, we agree that the reductionism “excesses” pose a risk, but we believe that these risks are due more to the need for adjustment in certain perspectives than to a social consequence directly related to the different ideological currents, either liberal, Marxist2. Human knowledge is cumulative. At the beginning of time, humans could boast of knowing almost everything. As that knowledge became more complex by the sum of discoveries, their interrelation, and the appearance of countless hypotheses and critiques, each science was no longer a part of a whole and compartmentalization began3. We see this phenomenon in law, medicine, physics, biology, political science, and so on. As everything has become more complex, study and research become fragmented, but none of these parts forgets that it is a part of a larger universe that all sciences integrate. What would medicine be if we were all general practitioners and did everything (clinic, neurosurgery, and attended births), and what would happen if the biologists did not specialize? Would everyone know all about all the species addressed? The author, Juan Emilio Sala","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88901814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surveillance for the identification of cases of acute respiratory infection by enterovirus D68 in children in a tertiary level care hospital during 2014-2016","authors":"A. Gamiño-Arroyo, J. Sánchez-Huerta, Alicia Elhaín de la Garza-López, I. Parra-Ortega, Noé Escobar-Escamilla, Edgar Mendieta-Condado, F. Garcés-Ayala, G. Barrera-Badillo, J. Ramírez-González, J. A. Díaz-Quiñónez, D. Rosa-Zamboni","doi":"10.24875/bmhime.m18000021","DOIUrl":"https://doi.org/10.24875/bmhime.m18000021","url":null,"abstract":"Background: The reemergence of enterovirus (EV) D68 infections in the United States was reported from August-October 2014 (691 cases). In Mexico, an outbreak at the National Institute of Respiratory Diseases was reported (24 cases). The results of epidemiological surveillance (ES) of enterovirus and other respiratory viruses in a national pediatric tertiary care level hospital are presented. Methods: Following the alert issued by the reemergence of EV-D68 in 2014, ES—which only detected respiratory viruses by PCR in patients with influenza-like illness using nasopharyngeal swabs—expanded to include children with asthma exacerbation or acute respiratory distress. Positive samples for Enterovirus sp. (EV) were confirmed and typed by sequencing. Subsequent sequencing was used to obtain the complete viral genome. Results: Of 1705 samples, 13 were positive to EV. Patients with EV presented the following comorbidities: chronic lung disease (7.7%), neoplastic disease (15.4%), allergic asthma/rhinitis (23%), recurrent pneumonia (23%), and other (23%). Of the 13 samples positive for EV, three were positive for EV-D68. These cases required invasive mechanical ventilation, presented no neurological involvement and survived. Conclusions: The impact of the population studied by EV-D68 was lower than that reported in the country during the same period. Cases of EV-D68 infection had multiple comorbidities, but few pulmonary comorbidities, which could explain the low attack rate. The ES and infection prevention system may have contained the outbreak.","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90424269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbial biofilms and their impact on medical areas: physiopathology, diagnosis and treatment","authors":"Silvestre Ortega-Peña, E. Hernández-Zamora","doi":"10.24875/bmhime.m18000026","DOIUrl":"https://doi.org/10.24875/bmhime.m18000026","url":null,"abstract":"","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82866225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}