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Null hypothesis 零假设
Pub Date : 2005-05-01 DOI: 10.1016/j.chs.2005.03.006
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引用次数: 0
Health and safety challenges in start-up of a multi-discipline/open lab research facility 多学科/开放实验室研究设施启动中的健康和安全挑战
Pub Date : 2005-05-01 DOI: 10.1016/j.chs.2004.03.013
Yong Kim, Russell Furr, Lawrence M. Gibbs, Ling Sue Teng

At Stanford University, the recent construction and development of a large multi-discipline research building provided Environmental Health & Safety (EH&S) staff with the opportunity to address safety and compliance issues before they become entrenched. This article discusses the challenges encountered and lessons learned in helping ensure the safe start-up of a large multi-discipline research laboratory building. Primary EH&S efforts taken include the use of an institutional laboratory health and safety planning and design guide, review of building plans, pre-move planning, post-move inspections, and walkthroughs.

在斯坦福大学,最近建设和发展的大型多学科研究大楼提供了环境健康和;安全(eh&&s)员工有机会在安全和合规问题变得根深蒂固之前解决这些问题。本文讨论了在帮助确保大型多学科研究实验室大楼安全启动时遇到的挑战和吸取的教训。主要的eh&&s工作包括使用机构实验室健康和安全规划和设计指南、审查建筑计划、搬迁前规划、搬迁后检查和演练。
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引用次数: 0
Laboratory ventilated sink use for glassware cleaning: Design, installation, and evaluation 用于玻璃器皿清洗的实验室通风水槽:设计、安装和评价
Pub Date : 2005-05-01 DOI: 10.1016/j.chs.2004.11.014
Ken Schmerber, Kevin Borud, Marc Rothney, Amy Doane

Numerous methods for cleaning laboratory glassware are currently available. Existing analytical method constraints at Roche Colorado Corporation (RCC), a Responsible Care company, limit the use of dishwashers and other automated glassware cleaning systems. Therefore, solvent-based laboratory glassware cleaning is performed to remove interfering residues, and represents an area of potential occupational exposure to chemicals. Typical cleaning steps include an initial solvent wash, soap and water cleansing, and a final solvent rinse to dry the glassware. Acetone, a common solvent used for this purpose, has an American Conference of Governmental Industrial Hygienist (ACGIH) TLV-TWA (8 hr) of 500 ppm and TLV-STEL (15 min) of 750 ppm. Exposure monitoring during glassware cleaning indicated that airborne concentrations of acetone may exceed these occupational exposure limits (OELs). To address the potential exposure to acetone vapors, engineering controls, consisting of a custom countertop slotted sink hood and an in-sink downdraft system, have been designed and implemented. Field validation indicated that both ventilated sinks were effective at controlling airborne acetone concentrations well below acetone's OELs.

目前有许多清洁实验室玻璃器皿的方法。罗氏科罗拉多公司(RCC)是一家责任关怀公司,现有的分析方法限制了洗碗机和其他自动玻璃器皿清洁系统的使用。因此,以溶剂为基础的实验室玻璃器皿清洗是为了去除干扰残留物,并代表潜在的职业接触化学品的区域。典型的清洗步骤包括最初的溶剂清洗,肥皂和水清洗,以及最后的溶剂冲洗以干燥玻璃器皿。丙酮是用于此目的的常用溶剂,美国政府工业卫生学家会议(ACGIH)的TLV-TWA(8小时)为500 ppm, TLV-STEL(15分钟)为750 ppm。玻璃器皿清洗期间的暴露监测表明,空气中丙酮的浓度可能超过这些职业暴露限值(OELs)。为了解决潜在的丙酮蒸汽暴露问题,设计并实施了工程控制,包括定制的台面开槽水槽罩和水槽内下沉系统。现场验证表明,这两种通风汇都能有效地控制空气中丙酮浓度远低于丙酮的OELs。
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引用次数: 2
CVS – No, it's not your corner drug store! CVS -不,它不是你的街角药店!
Pub Date : 2005-05-01 DOI: 10.1016/j.chs.2005.03.008
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引用次数: 0
Code corner 代码的角落
Pub Date : 2005-05-01 DOI: 10.1016/j.chs.2005.03.005
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引用次数: 0
“Chemicals” in the news and more “化学品”在新闻和更多
Pub Date : 2005-05-01 DOI: 10.1016/j.chs.2005.03.001
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引用次数: 0
News & Views 新闻及观点
Pub Date : 2005-05-01 DOI: 10.1016/j.chs.2005.03.010
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引用次数: 0
给编辑的信
Pub Date : 2005-05-01 DOI: 10.1016/j.chs.2005.03.004
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引用次数: 0
Biosecurity concerns: Changing the face of academic research 生物安全问题:改变学术研究的面貌
Pub Date : 2005-05-01 DOI: 10.1016/j.chs.2004.10.004
Ronald M. Atlas

The need for biodefense research in the wake of the anthrax attacks that followed 9/11 is changing the nature of research and the manner in which it is conducted on University campuses. A huge federal investment in biodefense is leading to more applied research conducted in high containment laboratories on college campuses. Biosecurity concerns are starting to exceed those of biosafety. Compliance with the many new oversight regulations is challenging to the research and safety communities. A series of legal cases discussed in this paper show that compliance is essential—the government is serious about criminal prosecution. The focus of biosecurity is not only on safeguarding dangerous pathogens and toxins; it also is directed to information and knowledge that may be misused. Systems are being developed that will force the academic safety community to determine what information is dangerous and what knowledge must be constrained.

在911之后的炭疽袭击之后,对生物防御研究的需求正在改变研究的性质和在大学校园进行研究的方式。联邦政府在生物防御方面的巨额投资,正促使更多的应用研究在大学校园的高密闭实验室进行。对生物安全的担忧开始超越对生物安全的担忧。遵守许多新的监管法规对研究和安全社区来说是一个挑战。本文讨论的一系列法律案例表明,合规是必要的——政府对刑事诉讼是认真的。生物安全的重点不仅在于保护危险的病原体和毒素;它还针对可能被滥用的信息和知识。正在开发的系统将迫使学术安全社区确定哪些信息是危险的,哪些知识必须受到限制。
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引用次数: 12
UPCOMING EVENTS 即将来临的事件
Pub Date : 2005-05-01 DOI: 10.1016/j.chs.2005.03.012
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引用次数: 0
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