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Does pelvic floor morphometry change in women with pelvic organ prolapse after a short period of supine lying? 患有盆腔器官脱垂的妇女在短时间仰卧后,盆底形态是否会发生变化?
Pub Date : 2024-06-14 DOI: 10.1016/j.contre.2024.100055
Lori B. Forner, Marie-Pierre Cyr, Paul W. Hodges, Michelle D. Smith

Introduction:

Advice for women with pelvic organ prolapse (POP) often includes lying down to decrease the effects of gravity on the pelvic floor. The aim of this study was to compare pelvic floor morphometry before and after 30 min of supine lying in women with symptomatic POP.

Methods:

Pelvic floor morphometry was assessed in vaginally parous, premenopausal women with symptomatic POP stage 1. The modified Pelvic Organ Prolapse Quantification system was used in supine to assess points Ba (anterior vaginal wall), Bp (posterior vaginal wall), and C (cervix). Transperineal ultrasound imaging was used in supine and standing to assess the following measures at rest and bearing down: bladder neck position, bladder position, rectal ampulla position, levator plate angle, anorectal angle, levator anteroposterior distance, and levator hiatal area. Measures taken before and after 30 min of supine lying were compared.

Results:

Twenty-one women (median (range) age: 39 (29–50) years) with varied stages of POP (33% stage 1, 57% stage 2, and 10% stage 3) were included. Most measures of pelvic floor morphometry were unchanged after 30 min of supine lying compared to before lying. Participants had greater resting levator hiatal area in supine and levator anteroposterior distance at rest and bearing down in supine after lying down (p 0.001), suggesting reduced pelvic floor muscle activity.

Conclusion:

Findings suggest that a 30-min period of supine lying does not improve support of the pelvic organs.

导言:为患有盆腔器官脱垂(POP)的女性提供的建议通常包括躺下以减少重力对盆底的影响。本研究的目的是比较有症状的POP妇女仰卧30分钟前后的盆底形态测量。方法:对有症状的POP≥1期的绝经前阴道旁妇女进行盆底形态测量评估。采用改良的盆腔器官脱垂定量系统,仰卧位评估Ba(阴道前壁)、Bp(阴道后壁)和C(宫颈)点。在仰卧和站立状态下使用经会阴超声波成像技术评估静息和负重时的以下指标:膀胱颈位置、膀胱位置、直肠安瓿位置、提肌板角度、肛门直肠角度、提肌前间距和提肌间隙面积。结果:21 名女性(中位数(范围)年龄:39(29-50)岁)患有不同阶段的 POP(33% 为 1 期,57% 为 2 期,10% 为 3 期)。仰卧 30 分钟后,大多数盆底形态测量指标与躺下前相比没有变化。结论:研究结果表明,仰卧 30 分钟并不能改善骨盆器官的支撑力。
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引用次数: 0
Urinary catheters and urinals throughout history 历史上的导尿管和小便池
Pub Date : 2024-06-04 DOI: 10.1016/j.contre.2024.100053

Emptying an overfilled bladder has been a severe medical problem in mankind since ancient times. This review presents highlights the main historical milestones in the development and use of urine catheters. Some of the most famous designers and makers are also commented. Besides, the historic role of urinals, both as sanitary elements and sometimes as therapeutic devices for male incontinence, is presented.

自古以来,排空过度充盈的膀胱一直是人类面临的严重医疗问题。本综述重点介绍了导尿管开发和使用的主要历史里程碑。文中还介绍了一些最著名的设计者和制造者。此外,还介绍了小便池的历史作用,它既是卫生设备,有时也是治疗男性尿失禁的设备。
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引用次数: 0
Bladder dysfunction caused by tuberculosis: A historical review 结核病导致的膀胱功能障碍:历史回顾
Pub Date : 2024-05-29 DOI: 10.1016/j.contre.2024.100052
Etienne Cuénant , Philip Van Kerrebroeck

Tuberculosis has become an infrequent disease in Western society, hence has tuberculosis of the bladder. However, when tuberculosis was prevalent, urogenital tuberculosis and tuberculosis of the bladder could be the consequence if untreated, and were responsible for severe bladder dysfunction. Before antibiotic treatment became available, chronic bladder tuberculosis caused irreversible damage and often necessitated bladder reconstruction or even cystectomy. The specific antibiotic treatment of tuberculosis eradicated bladder dysfunction caused by tuberculosis. We aim to review the history of urogenital tuberculosis and the consequent dysfunction of the bladder based on existing literature.

在西方社会,肺结核已成为一种不常见的疾病,膀胱结核也是如此。然而,在结核病流行时,泌尿生殖系统结核和膀胱结核如不及时治疗,可能会导致严重的膀胱功能障碍。在抗生素治疗出现之前,慢性膀胱结核会造成不可逆转的损害,往往需要进行膀胱重建甚至膀胱切除术。结核病的特效抗生素治疗根除了结核病引起的膀胱功能障碍。我们旨在根据现有文献回顾泌尿生殖系统结核的历史以及由此导致的膀胱功能障碍。
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引用次数: 0
Sterile abscess formation following periurethral injections with synthetic polycaprolactone microspheres suspended in a carboxymethylcellulose gel (Urolon®): A case report 尿道周围注射悬浮在羧甲基纤维素凝胶(Urolon®)中的合成聚己内酯微球后形成无菌脓肿:病例报告
Pub Date : 2024-05-09 DOI: 10.1016/j.contre.2024.100050
J.E.M. Budo, J.P. Heesakkers

Periurethral injection of bulking agents is a technique used to treat urinary incontinence due to stress incontinence, preferably caused by intrinsic sphincter deficiency. The variety of the nature of existing bulking agents leads to different success rates and complications. This case report describes the formation of pseudo-abscesses after periurethral injections with a bioresorbable implant consisting of synthetic polycaprolactone microspheres suspended in a carboxymethylcellulose gel carrier.

尿道周围注射膨大剂是一种用于治疗应力性尿失禁的技术,这种尿失禁最好是由内在括约肌缺陷引起的。现有膨大剂的性质各异,导致成功率和并发症也不尽相同。本病例报告描述了尿道周围注射生物可吸收植入物后形成假性脓肿的情况,该植入物由悬浮在羧甲基纤维素凝胶载体中的合成聚己内酯微球组成。
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引用次数: 0
A novel clinical classification for male urinary incontinence: MI-CRONS 男性尿失禁的新型临床分类:MI-CRONS
Pub Date : 2024-05-09 DOI: 10.1016/j.contre.2024.100051
George Kasyan , Bagrat Grigoryan , Dmitry Pushkar

Introduction:

The aim of this study is to develop a new simple and practical classification of male urinary incontinence (UI) based on the clinical features and type of urinary incontinence.

Materials & methods:

MI-CRONS classification is a system based on severity of incontinence and patients’ characteristics. Clinical evaluation of incontinence severity is based on preservation of voiding, proportion of void/lost urine, absorbable device usage, level of physical efforts that causes urine loss and nocturnal incontinence. Following patients’ characteristics of patients were included in classification system: history of radical prostatectomy, history of pelvic radiation, surgery for prostatic obstruction, neurogenic or non-neurogenic bladder disorders, and urethral strictures and disorders. This MI-CRONS classification system uses five uppercase Latin letters as follows: Male Incontinence — Cancer, Radiation, Obstruction, Neurogenic, Stricture. The classification could be used for stress, urgency, and mixed UI forms.

Results:

The new MI-CRONS classification system was applied to 85 of 86 patients evaluated in this retrospective study. Patients were classified by MI-CRONS to estimate an inclusiveness and complicity of proposed classification only. One patient was not classified using the new MI-CRONS classification due to history of bladder exstrophy and augmentation cystoplasty. Most of the men studied had a stress form of urinary incontinence and the most common types were 2 (n = 18) and 3 (n = 17) after radical prostatectomy.

Conclusion:

The MI-CRONS has demonstrated prompt potential for classifying male incontinence of any type. The classification is a simple tool to describe these patients and could be useful for daily practice and clinical trials. Although further multicenter studies are needed to evaluate the predictive value of this tool. A Delphi consensus would be proposed with international experts for the further development of MI-CRONS.

导读:本研究旨在根据尿失禁的临床特征和类型,对男性尿失禁(UI)进行一种新的简单实用的分类。尿失禁严重程度的临床评估基于排尿时间、排尿/遗尿比例、可吸收装置的使用、导致遗尿的体力劳动程度和夜间尿失禁。分类系统包括以下患者特征:根治性前列腺切除术史、盆腔放射史、前列腺阻塞手术史、神经源性或非神经源性膀胱疾病以及尿道狭窄和疾病。该 MI-CRONS 分类系统使用以下五个大写拉丁字母:男性尿失禁--癌症、辐射、梗阻、神经源性、狭窄。结果:在这项回顾性研究中,86 位接受评估的患者中有 85 位采用了新的 MI-CRONS 分类系统。通过 MI-CRONS 对患者进行分类,只是为了评估拟议分类的包容性和并发症。有一名患者由于曾患膀胱外翻和膀胱成形术,因此没有采用新的 MI-CRONS 分类法。结论:MI-CRONS已被证明具有对任何类型的男性尿失禁进行分类的潜力。结论:MI-CRONS 显示出了对任何类型的男性尿失禁进行及时分类的潜力,该分类是描述这些患者的简单工具,可用于日常实践和临床试验。尽管还需要进一步的多中心研究来评估该工具的预测价值。建议与国际专家达成德尔菲共识,以进一步开发 MI-CRONS。
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引用次数: 0
The durability of filter cap for OT-Balloon catheter, a novel urethral catheter for intermittent balloon catheterization 用于间歇性球囊导尿的新型尿道导管 OT-Balloon 导管过滤帽的耐用性
Pub Date : 2024-05-04 DOI: 10.1016/j.contre.2024.100049
Tomofumi Watanabe , Motoo Araki , Takuya Sadahira

Objective:

The OT-Balloon Catheter is a novel urethral catheter designed for intermittent balloon catheterization. It has a filter permeable to gases but not liquids, enabling patients to confirm adequate catheterization without the flow of urine. This study examined the characteristics of the filter cap for OT-Balloon Catheter by repeatedly exposing filters to urine samples in 2 different conditions.

Methods:

Urine samples were collected from 10 patients who required clean intermittent catheterization and visited Okayama University Hospital in 2023. Filters of the cap for OT-Balloon Catheter were exposed to urine samples for 30 times under 2 conditions, as follows: condition A, filters were rinsed with running water after exposure to urine; condition B, filters were never rinsed throughout the experiment. The permeability of the filters during and after the exposure was examined. The filter surface was also analyzed by stereomicroscopy.

Results:

None of the filters were blocked after treatment in condition A. More than 50% of the filters remained permeable after 20 and 30 exposures even in condition B. Long-term storage did not lead to increased rates of blockage. Microscopic examination found minimal urine stains on the surface of filters under condition B.

Conclusion:

The filter cap for OT-Balloon Catheter was resistant to blockage and maintained permeability after exposure to urine when adequately rinsed, and also when never rinsed after exposure to most samples. The durable permeability of the filter enables patients to achieve rapid, safe, and easy intermittent balloon catheterization.

目标:OT-球囊导管是一种新型尿道导管,设计用于间歇性球囊导管插入术。它有一个可渗透气体但不能渗透液体的过滤器,使患者能够在没有尿液流出的情况下确认导管导入是否充分。本研究通过在 2 种不同条件下反复将过滤器暴露于尿液样本,对 OT 球囊导尿管过滤器盖的特性进行了研究。在以下两种条件下,OT-球囊导尿管帽的过滤器与尿液样本接触 30 次:条件 A,过滤器接触尿液后用流动水冲洗;条件 B,过滤器在整个实验过程中从未冲洗。在接触过程中和接触后,对过滤器的渗透性进行检测。结果:在条件 A 中,没有一个过滤器在处理后发生堵塞;即使在条件 B 中,超过 50% 的过滤器在暴露 20 次和 30 次后仍可渗透。结论:OT-球囊导尿管的滤器盖在充分冲洗后不易堵塞,并且在接触尿液后仍能保持通透性,在接触大多数样本后从未冲洗也能保持通透性。过滤器的持久通透性使患者能够快速、安全、轻松地进行间歇性球囊导管插入术。
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引用次数: 0
Effectiveness of Carbamazepine in the treatment of refractory secondary enuresis: A case report 卡马西平治疗难治性继发性遗尿症的疗效:病例报告
Pub Date : 2024-04-23 DOI: 10.1016/j.contre.2024.100048
Andretta Elena , Rosato Eleonora , Zuliani Cristina , Finazzi Agrò Enrico

A 42-year-old woman was referred by neurology colleagues to our outpatient urology clinics. She presented with a non-monosymptomatic secondary enuresis, which started at 20 years of age When she was twenty-two she presented a single episode of a generalised tonic-clonic seizure, and she was treated with Carbamazepine (CBZ) with resolution of enuresis that reappeared when CBZ was stopped. Therefore, a video-EEG was performed, which documented an episode of enuresis during stage 1 of non-REM sleep without epileptic discharges and made it difficult for the patient to reach the deeper stages of sleep. According to these findings, the epileptic genesis of the enuresis was ruled out. A urodynamic invasive study was performed, and a normal active bladder associated with sleep disturbances was diagnosed as the combined cause of the non-monosymptomatic secondary nocturnal enuresis.

Behavioural therapy and/or antimuscarinic treatments, alone or in combination, were used without success. Then the patient restarted CBZ at a low dose (200 mg/day), and a significant reduction of enuresis episodes (1 wet night every 9–10) was obtained with no changes in the bladder diary.

CBZ effectiveness in such a case on an overactive bladder (OAB) could depend on its modulating effect in the central nervous system.

神经科的同事将一名 42 岁的女性转介到我们的泌尿科门诊。她从 20 岁开始出现无单发症状的继发性遗尿症,22 岁时曾有过一次全身强直阵挛发作,接受卡马西平(CBZ)治疗后遗尿症有所缓解,但停用 CBZ 后又再次出现遗尿症。因此,对她进行了视频脑电图检查,结果显示她在非快速眼动睡眠的第一阶段出现了一次遗尿,但没有癫痫放电,这使得患者难以进入更深的睡眠阶段。根据这些结果,排除了遗尿症由癫痫引起的可能性。患者接受了尿动力学有创检查,被诊断为正常活动性膀胱伴有睡眠障碍,是非单症状继发性夜间遗尿症的综合病因。后来,患者重新开始服用小剂量(200 毫克/天)的 CBZ,结果遗尿次数明显减少(每 9-10 个晚上遗尿 1 次),而膀胱日记没有任何变化。
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引用次数: 0
Erratum to “COVID-19- associated Guillain–Barrè Syndrome and Urinary Dysfunction: A case report” [Cont. Rep. 4 (2022) 100017] COVID-19相关格林-巴利综合征和排尿功能障碍:病例报告" [Cont. Rep. 4 (2022) 100017] 更正
Pub Date : 2024-03-01 DOI: 10.1016/j.contre.2023.100045
Marilena Gubbiotti , Wally Mahfouz , Anastasios D. Asimakopoulos , Ludovica Durante , Giacomo Maria Pirola , Daniele Castellani , Emanuele Rubilotta
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引用次数: 0
Single-incision vaginal mesh insertion for recurrent vaginal vault prolapse after radical cystectomy and radical hysterectomy with irradiation: A case report 单切口阴道网片植入术治疗根治性膀胱切除术和根治性子宫切除术加照射术后复发性阴道穹隆脱垂:病例报告
Pub Date : 2024-02-01 DOI: 10.1016/j.contre.2024.100047
Zoltan Nemeth , Roxana Schmidt , Balint Farkas

A 74-year-old female patient five month after radical robot assisted cystectomy (RC) with ileal conduit (IC) presented to our department with stage 4 symptomatic vaginal prolapse and anterior enterocele (AE). In the medical history 43 years ago radical hysterectomy (Piver 3) was revealed followed by postoperative irradiation and brachytherapy, due to invasive cervical cancer. A total colpocleisis was carried out as a first line therapy. A recurrence occurred 8 months after the first surgery. We used a customized single-incision vaginal mesh for the relapse operation. The patient has been symptomless for 50 months. We believe that vaginal irradiation is a rare but significant risk factor for the development of anterior enterocele after RC with IC and single-incision tailored vaginal mesh insertion for symptomatic anterior enterocele after radical cystectomy and radical hysterectomy with irradiation may be a long-term surgical solution.

一位74岁的女性患者在接受机器人辅助膀胱根治术(RC)和回肠导管术(IC)5个月后,因第四期症状性阴道脱垂和前肠裂(AE)来我科就诊。病史显示,该患者 43 年前因浸润性宫颈癌行根治性子宫切除术(Piver 3),术后接受了放射治疗和近距离放射治疗。作为一线治疗,她接受了全阴道切除术。第一次手术后 8 个月复发。我们在复发手术中使用了定制的单切口阴道网片。该患者已50个月无症状。我们认为,阴道辐照是膀胱癌根治术(RC)合并子宫内膜异位症(IC)术后发生前肠膨出的一个罕见但重要的风险因素,而对于根治性膀胱切除术和根治性子宫切除术合并辐照术后的症状性前肠膨出,单切口定制阴道网片植入术可能是一种长期的手术解决方案。
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引用次数: 0
Erratum to: “Neurogenic voiding dysfunction induced by vitamin B6 overdose” [Continence Rep. 1 (2022) 100004] 勘误:"维生素 B6 过量诱发的神经源性排尿功能障碍》[Continence Rep. 1 (2022) 100004] 更正
Pub Date : 2023-12-01 DOI: 10.1016/j.contre.2023.100038
T. Van den Broeck , B. Crul , J.P. Heesakkers
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引用次数: 0
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Continence Reports
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