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A novel clinical classification for male urinary incontinence: MI-CRONS 男性尿失禁的新型临床分类:MI-CRONS
Pub Date : 2024-05-09 DOI: 10.1016/j.contre.2024.100051
George Kasyan , Bagrat Grigoryan , Dmitry Pushkar

Introduction:

The aim of this study is to develop a new simple and practical classification of male urinary incontinence (UI) based on the clinical features and type of urinary incontinence.

Materials & methods:

MI-CRONS classification is a system based on severity of incontinence and patients’ characteristics. Clinical evaluation of incontinence severity is based on preservation of voiding, proportion of void/lost urine, absorbable device usage, level of physical efforts that causes urine loss and nocturnal incontinence. Following patients’ characteristics of patients were included in classification system: history of radical prostatectomy, history of pelvic radiation, surgery for prostatic obstruction, neurogenic or non-neurogenic bladder disorders, and urethral strictures and disorders. This MI-CRONS classification system uses five uppercase Latin letters as follows: Male Incontinence — Cancer, Radiation, Obstruction, Neurogenic, Stricture. The classification could be used for stress, urgency, and mixed UI forms.

Results:

The new MI-CRONS classification system was applied to 85 of 86 patients evaluated in this retrospective study. Patients were classified by MI-CRONS to estimate an inclusiveness and complicity of proposed classification only. One patient was not classified using the new MI-CRONS classification due to history of bladder exstrophy and augmentation cystoplasty. Most of the men studied had a stress form of urinary incontinence and the most common types were 2 (n = 18) and 3 (n = 17) after radical prostatectomy.

Conclusion:

The MI-CRONS has demonstrated prompt potential for classifying male incontinence of any type. The classification is a simple tool to describe these patients and could be useful for daily practice and clinical trials. Although further multicenter studies are needed to evaluate the predictive value of this tool. A Delphi consensus would be proposed with international experts for the further development of MI-CRONS.

导读:本研究旨在根据尿失禁的临床特征和类型,对男性尿失禁(UI)进行一种新的简单实用的分类。尿失禁严重程度的临床评估基于排尿时间、排尿/遗尿比例、可吸收装置的使用、导致遗尿的体力劳动程度和夜间尿失禁。分类系统包括以下患者特征:根治性前列腺切除术史、盆腔放射史、前列腺阻塞手术史、神经源性或非神经源性膀胱疾病以及尿道狭窄和疾病。该 MI-CRONS 分类系统使用以下五个大写拉丁字母:男性尿失禁--癌症、辐射、梗阻、神经源性、狭窄。结果:在这项回顾性研究中,86 位接受评估的患者中有 85 位采用了新的 MI-CRONS 分类系统。通过 MI-CRONS 对患者进行分类,只是为了评估拟议分类的包容性和并发症。有一名患者由于曾患膀胱外翻和膀胱成形术,因此没有采用新的 MI-CRONS 分类法。结论:MI-CRONS已被证明具有对任何类型的男性尿失禁进行分类的潜力。结论:MI-CRONS 显示出了对任何类型的男性尿失禁进行及时分类的潜力,该分类是描述这些患者的简单工具,可用于日常实践和临床试验。尽管还需要进一步的多中心研究来评估该工具的预测价值。建议与国际专家达成德尔菲共识,以进一步开发 MI-CRONS。
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引用次数: 0
The durability of filter cap for OT-Balloon catheter, a novel urethral catheter for intermittent balloon catheterization 用于间歇性球囊导尿的新型尿道导管 OT-Balloon 导管过滤帽的耐用性
Pub Date : 2024-05-04 DOI: 10.1016/j.contre.2024.100049
Tomofumi Watanabe , Motoo Araki , Takuya Sadahira

Objective:

The OT-Balloon Catheter is a novel urethral catheter designed for intermittent balloon catheterization. It has a filter permeable to gases but not liquids, enabling patients to confirm adequate catheterization without the flow of urine. This study examined the characteristics of the filter cap for OT-Balloon Catheter by repeatedly exposing filters to urine samples in 2 different conditions.

Methods:

Urine samples were collected from 10 patients who required clean intermittent catheterization and visited Okayama University Hospital in 2023. Filters of the cap for OT-Balloon Catheter were exposed to urine samples for 30 times under 2 conditions, as follows: condition A, filters were rinsed with running water after exposure to urine; condition B, filters were never rinsed throughout the experiment. The permeability of the filters during and after the exposure was examined. The filter surface was also analyzed by stereomicroscopy.

Results:

None of the filters were blocked after treatment in condition A. More than 50% of the filters remained permeable after 20 and 30 exposures even in condition B. Long-term storage did not lead to increased rates of blockage. Microscopic examination found minimal urine stains on the surface of filters under condition B.

Conclusion:

The filter cap for OT-Balloon Catheter was resistant to blockage and maintained permeability after exposure to urine when adequately rinsed, and also when never rinsed after exposure to most samples. The durable permeability of the filter enables patients to achieve rapid, safe, and easy intermittent balloon catheterization.

目标:OT-球囊导管是一种新型尿道导管,设计用于间歇性球囊导管插入术。它有一个可渗透气体但不能渗透液体的过滤器,使患者能够在没有尿液流出的情况下确认导管导入是否充分。本研究通过在 2 种不同条件下反复将过滤器暴露于尿液样本,对 OT 球囊导尿管过滤器盖的特性进行了研究。在以下两种条件下,OT-球囊导尿管帽的过滤器与尿液样本接触 30 次:条件 A,过滤器接触尿液后用流动水冲洗;条件 B,过滤器在整个实验过程中从未冲洗。在接触过程中和接触后,对过滤器的渗透性进行检测。结果:在条件 A 中,没有一个过滤器在处理后发生堵塞;即使在条件 B 中,超过 50% 的过滤器在暴露 20 次和 30 次后仍可渗透。结论:OT-球囊导尿管的滤器盖在充分冲洗后不易堵塞,并且在接触尿液后仍能保持通透性,在接触大多数样本后从未冲洗也能保持通透性。过滤器的持久通透性使患者能够快速、安全、轻松地进行间歇性球囊导管插入术。
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引用次数: 0
Effectiveness of Carbamazepine in the treatment of refractory secondary enuresis: A case report 卡马西平治疗难治性继发性遗尿症的疗效:病例报告
Pub Date : 2024-04-23 DOI: 10.1016/j.contre.2024.100048
Andretta Elena , Rosato Eleonora , Zuliani Cristina , Finazzi Agrò Enrico

A 42-year-old woman was referred by neurology colleagues to our outpatient urology clinics. She presented with a non-monosymptomatic secondary enuresis, which started at 20 years of age When she was twenty-two she presented a single episode of a generalised tonic-clonic seizure, and she was treated with Carbamazepine (CBZ) with resolution of enuresis that reappeared when CBZ was stopped. Therefore, a video-EEG was performed, which documented an episode of enuresis during stage 1 of non-REM sleep without epileptic discharges and made it difficult for the patient to reach the deeper stages of sleep. According to these findings, the epileptic genesis of the enuresis was ruled out. A urodynamic invasive study was performed, and a normal active bladder associated with sleep disturbances was diagnosed as the combined cause of the non-monosymptomatic secondary nocturnal enuresis.

Behavioural therapy and/or antimuscarinic treatments, alone or in combination, were used without success. Then the patient restarted CBZ at a low dose (200 mg/day), and a significant reduction of enuresis episodes (1 wet night every 9–10) was obtained with no changes in the bladder diary.

CBZ effectiveness in such a case on an overactive bladder (OAB) could depend on its modulating effect in the central nervous system.

神经科的同事将一名 42 岁的女性转介到我们的泌尿科门诊。她从 20 岁开始出现无单发症状的继发性遗尿症,22 岁时曾有过一次全身强直阵挛发作,接受卡马西平(CBZ)治疗后遗尿症有所缓解,但停用 CBZ 后又再次出现遗尿症。因此,对她进行了视频脑电图检查,结果显示她在非快速眼动睡眠的第一阶段出现了一次遗尿,但没有癫痫放电,这使得患者难以进入更深的睡眠阶段。根据这些结果,排除了遗尿症由癫痫引起的可能性。患者接受了尿动力学有创检查,被诊断为正常活动性膀胱伴有睡眠障碍,是非单症状继发性夜间遗尿症的综合病因。后来,患者重新开始服用小剂量(200 毫克/天)的 CBZ,结果遗尿次数明显减少(每 9-10 个晚上遗尿 1 次),而膀胱日记没有任何变化。
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引用次数: 0
Erratum to “COVID-19- associated Guillain–Barrè Syndrome and Urinary Dysfunction: A case report” [Cont. Rep. 4 (2022) 100017] COVID-19相关格林-巴利综合征和排尿功能障碍:病例报告" [Cont. Rep. 4 (2022) 100017] 更正
Pub Date : 2024-03-01 DOI: 10.1016/j.contre.2023.100045
Marilena Gubbiotti , Wally Mahfouz , Anastasios D. Asimakopoulos , Ludovica Durante , Giacomo Maria Pirola , Daniele Castellani , Emanuele Rubilotta
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引用次数: 0
Single-incision vaginal mesh insertion for recurrent vaginal vault prolapse after radical cystectomy and radical hysterectomy with irradiation: A case report 单切口阴道网片植入术治疗根治性膀胱切除术和根治性子宫切除术加照射术后复发性阴道穹隆脱垂:病例报告
Pub Date : 2024-02-01 DOI: 10.1016/j.contre.2024.100047
Zoltan Nemeth , Roxana Schmidt , Balint Farkas

A 74-year-old female patient five month after radical robot assisted cystectomy (RC) with ileal conduit (IC) presented to our department with stage 4 symptomatic vaginal prolapse and anterior enterocele (AE). In the medical history 43 years ago radical hysterectomy (Piver 3) was revealed followed by postoperative irradiation and brachytherapy, due to invasive cervical cancer. A total colpocleisis was carried out as a first line therapy. A recurrence occurred 8 months after the first surgery. We used a customized single-incision vaginal mesh for the relapse operation. The patient has been symptomless for 50 months. We believe that vaginal irradiation is a rare but significant risk factor for the development of anterior enterocele after RC with IC and single-incision tailored vaginal mesh insertion for symptomatic anterior enterocele after radical cystectomy and radical hysterectomy with irradiation may be a long-term surgical solution.

一位74岁的女性患者在接受机器人辅助膀胱根治术(RC)和回肠导管术(IC)5个月后,因第四期症状性阴道脱垂和前肠裂(AE)来我科就诊。病史显示,该患者 43 年前因浸润性宫颈癌行根治性子宫切除术(Piver 3),术后接受了放射治疗和近距离放射治疗。作为一线治疗,她接受了全阴道切除术。第一次手术后 8 个月复发。我们在复发手术中使用了定制的单切口阴道网片。该患者已50个月无症状。我们认为,阴道辐照是膀胱癌根治术(RC)合并子宫内膜异位症(IC)术后发生前肠膨出的一个罕见但重要的风险因素,而对于根治性膀胱切除术和根治性子宫切除术合并辐照术后的症状性前肠膨出,单切口定制阴道网片植入术可能是一种长期的手术解决方案。
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引用次数: 0
Erratum to: “Neurogenic voiding dysfunction induced by vitamin B6 overdose” [Continence Rep. 1 (2022) 100004] 勘误:"维生素 B6 过量诱发的神经源性排尿功能障碍》[Continence Rep. 1 (2022) 100004] 更正
Pub Date : 2023-12-01 DOI: 10.1016/j.contre.2023.100038
T. Van den Broeck , B. Crul , J.P. Heesakkers
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引用次数: 0
Lower Urinary Tract Symptoms (LUTS) and COVID-19 下尿路症状(LUTS)与COVID-19
Pub Date : 2023-12-01 DOI: 10.1016/j.contre.2023.100044
Sona Tayebi , Mohammad Sajjad Rahnama’i , Ashkan Shafigh , Hanieh Salehi-Pourmehr , Hadi Mostafaei , Ehsan Sepehran , Sakineh Hajebrahimi

The COVID-19 has been a great challenge for healthcare providers all over the world which overwhelmed patients and healthcare providers by postponing many outpatient appointments and surgical procedures for months. Interestingly, COVID-19 can cause de novo lower urinary tract symptoms (LUTS) in some affected patients or exacerbate underlying LUTS in others although the most prevalent symptoms are respiratory symptoms. Understanding the effects of COVID-19 on LUTS is crucial for establishing bladder inflammation. In this review, we are focusing on how the lower urinary tract would be affected by COVID-19, considering the pathophysiology, and clinical implication of COVID-19-associated LUTS.

COVID-19对世界各地的医疗保健提供者来说是一个巨大的挑战,许多门诊预约和外科手术推迟了数月,使患者和医疗保健提供者不堪重负。有趣的是,尽管最常见的症状是呼吸道症状,但COVID-19可在一些受影响的患者中引起新发下尿路症状(LUTS)或加剧其他患者的潜在下尿路症状。了解COVID-19对LUTS的影响对于建立膀胱炎症至关重要。在这篇综述中,我们将重点关注COVID-19对下尿路的影响,并考虑COVID-19相关LUTS的病理生理和临床意义。
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引用次数: 0
Novel finding: Proteinuria in patients with a urinary diversion does not predict renal function decline 新发现:尿分流患者的蛋白尿不能预测肾功能下降
Pub Date : 2023-11-07 DOI: 10.1016/j.contre.2023.100043
E.J.O. Claessens , P.D. Polm , M.B. Rookmaaker , L.M.O. de Kort

Purpose:

Proteinuria is used to track down patients with intrinsic renal disease and increased risk of renal function decline and is seen in up to 5% in the general population. The aim of this study is to investigate the prevalence and clinical relevance of proteinuria regarding renal function in patients with a urinary diversion.

Methods:

Data was collected of patients with a urinary diversion who had a follow-up appointment (T1) in the Urology Department of the University Hospital Utrecht in 2021. Patients were divided into a proteinuria and no proteinuria group. Proteinuria was determined through dipstick urinalysis at T1. Glomerular filtration rate and renal imaging were analysed at T1 and after 11–30 months follow-up (T2).

Results:

A research population of 84 patients was identified, median age was 38 years, 39.3% was male. At T1, 43% had proteinuria. There was no association between proteinuria and glomerular filtration rate nor abnormalities on renal imaging at T1 or T2. No statistically significant difference was seen in the glomerular filtration rate decline after 11–30 months between the group with and without proteinuria, determined at T1 (respectively 1.3 ± 6.9 ml/min/1.73 m2 vs 2.3 ± 9.5 ml/min/1.73 m2; p-value 0.63).

Conclusion:

The prevalence of proteinuria in patients with a urinary diversion is high. Proteinuria was not associated with renal function or renal function decline over time. These findings illustrate the limitations of proteinuria screening to identify individuals at risk for renal function decline among this population.

目的:蛋白尿用于追踪患有内在肾脏疾病和肾功能下降风险增加的患者,在一般人群中高达5%。本研究的目的是调查蛋白尿在尿分流患者中与肾功能的患病率和临床相关性。方法:收集乌得勒支大学医院泌尿外科2021年随访预约(T1)的尿转流患者的数据。将患者分为蛋白尿组和无蛋白尿组。T1时用试纸尿法测定蛋白尿。在T1和随访11-30个月(T2)后分析肾小球滤过率和肾脏影像学。结果:纳入研究人群84例,中位年龄38岁,男性占39.3%。T1时,43%有蛋白尿。蛋白尿与肾小球滤过率之间无相关性,T1或T2时肾脏影像学也无异常。11-30个月后,有蛋白尿组和无蛋白尿组的肾小球滤过率下降无统计学差异,T1测定值分别为1.3±6.9 ml/min/1.73 m2和2.3±9.5 ml/min/1.73 m2;假定值0.63)。结论:尿改道患者蛋白尿发生率高。蛋白尿与肾功能或肾功能随时间下降无关。这些发现说明了蛋白尿筛查在这一人群中识别有肾功能下降风险的个体的局限性。
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引用次数: 0
Erratum to “Neurosyphilis-an uncommon cause of neurogenic lower urinary tract dysfunction” [Cont. Rep. 6 (2023) 100024] “神经梅毒是神经源性下尿路功能障碍的罕见原因”勘误表[续第6(2023)100024]
Pub Date : 2023-10-06 DOI: 10.1016/j.contre.2023.100042
Matthew Playfair , Blayne Welk
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引用次数: 0
Erratum to “Paraurethral leiomyoma in a 22-year-old woman: A case report” [Cont. Rep. 3 (2022) 100014] “一名22岁女性尿道旁平滑肌瘤:病例报告”勘误表[续,代表3(2022)100014]
Pub Date : 2023-10-06 DOI: 10.1016/j.contre.2023.100041
Samia Aijaz, Novera Chughtai, Urooj Kashif, Summera Malik
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引用次数: 0
期刊
Continence Reports
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