Hope plays a crucial role in the well-being of youth, impacting various aspects of their lives. However, less is known about the role of hope in pre-adolescents. This study aims to explore the psychosocial and behavioral correlates of hope in 9–10-year-old pre-youth transitioning into adolescence.
Methods
Using data from the Adolescent Brain Cognitive Development (ABCD) study, 4631 youth entered our study. The investigation follows these individuals for up to 36 months, specifically observing the initiation of marijuana and tobacco use. The methods employed include bivariate correlations.
Results
Baseline high hope offered protection against marijuana and tobacco use over the following 36 months. Elevated levels of hope could be seen in pre-youth with higher family income and those experienced lower levels of stressful life events and financial difficulties. High hope was also linked to lower behavioral problems, improved emotional function, lower impulsivity, lower sensation seeking, and higher cognitive function. Notably, hope was not correlated with parental education, neighborhood income, family conflict, blood pressure, body mass index, grade point average, prosocial behaviors, or puberty.
Conclusion
In conclusion, the findings suggest a close interplay between hope and various dimensions of resilience including lower tobacco and marijuana use. Higher levels of hope, influenced by factors such as family income and life events, may be a mechanism that connects hope to enhanced emotional and cognitive functioning and acts as a protective factor against early initiation of substance use. These findings underscore the potential utility of fostering hope as a strategy to promote positive development and reduce tobacco and marijuana use.
{"title":"Behavioral and psychosocial correlates of hope among youth","authors":"Shervin Assari , Babak Najand , Izadrad Najand , Stephen Grace","doi":"10.1016/j.glmedi.2024.100088","DOIUrl":"https://doi.org/10.1016/j.glmedi.2024.100088","url":null,"abstract":"<div><h3>Introduction</h3><p>Hope plays a crucial role in the well-being of youth, impacting various aspects of their lives. However, less is known about the role of hope in pre-adolescents. This study aims to explore the psychosocial and behavioral correlates of hope in 9–10-year-old pre-youth transitioning into adolescence.</p></div><div><h3>Methods</h3><p>Using data from the Adolescent Brain Cognitive Development (ABCD) study, 4631 youth entered our study. The investigation follows these individuals for up to 36 months, specifically observing the initiation of marijuana and tobacco use. The methods employed include bivariate correlations.</p></div><div><h3>Results</h3><p>Baseline high hope offered protection against marijuana and tobacco use over the following 36 months. Elevated levels of hope could be seen in pre-youth with higher family income and those experienced lower levels of stressful life events and financial difficulties. High hope was also linked to lower behavioral problems, improved emotional function, lower impulsivity, lower sensation seeking, and higher cognitive function. Notably, hope was not correlated with parental education, neighborhood income, family conflict, blood pressure, body mass index, grade point average, prosocial behaviors, or puberty.</p></div><div><h3>Conclusion</h3><p>In conclusion, the findings suggest a close interplay between hope and various dimensions of resilience including lower tobacco and marijuana use. Higher levels of hope, influenced by factors such as family income and life events, may be a mechanism that connects hope to enhanced emotional and cognitive functioning and acts as a protective factor against early initiation of substance use. These findings underscore the potential utility of fostering hope as a strategy to promote positive development and reduce tobacco and marijuana use.</p></div>","PeriodicalId":100804,"journal":{"name":"Journal of Medicine, Surgery, and Public Health","volume":"2 ","pages":"Article 100088"},"PeriodicalIF":0.0,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949916X24000410/pdfft?md5=678fdb5254d927f00ddaa9f2e3127972&pid=1-s2.0-S2949916X24000410-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140138432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-13DOI: 10.1016/j.glmedi.2024.100084
Shervin Assari , Babak Najand , Hossein Zare
Introduction
Residential stability is increasingly recognized as a significant factor influencing youth positive development. While the existing body of research provides valuable insights, gaps remain regarding the determinants of residential stability and how its outcomes may vary by gender and race. This study aims to investigate the relationship between residential stability, substance use, and behavioral issues among children aged 9–10 years, with a focus on the mediating role of trauma exposure.
Methods
This research utilizes data from the Adolescent Brain Cognitive Development (ABCD) study, a longitudinal project initiated in 2016 with a sample of 11,849 participants. It explores the links between residential stability, socioeconomic factors, stress, and emotional and behavioral outcomes using the Child Behavior Checklist (CBCL). Structural equation modeling was employed to analyze the data.
Results findings
indicate that higher household income, living in a household with married parents, and residing in areas with greater household incomes correlate with residential stability. In turn, residential stability is linked to lower levels of life stress and reduced substance use in the future. Furthermore, the impact of residential stability on substance uses and CBCL scores was entirely mediated by trauma exposure.
Conclusions
The findings advocate for the implementation of economic, social, and public policies aimed at fostering stable living environments for children and families to mitigate the emotional and behavioral challenges future generations may face. Enhancing socioeconomic status and supporting structures that promote married family living arrangements emerge as effective strategies to improve residential stability and the well-being of young people in the United States.
{"title":"The link between residential stability and youth substance use: Role of stressful life events and behavioral problems","authors":"Shervin Assari , Babak Najand , Hossein Zare","doi":"10.1016/j.glmedi.2024.100084","DOIUrl":"https://doi.org/10.1016/j.glmedi.2024.100084","url":null,"abstract":"<div><h3>Introduction</h3><p>Residential stability is increasingly recognized as a significant factor influencing youth positive development. While the existing body of research provides valuable insights, gaps remain regarding the determinants of residential stability and how its outcomes may vary by gender and race. This study aims to investigate the relationship between residential stability, substance use, and behavioral issues among children aged 9–10 years, with a focus on the mediating role of trauma exposure.</p></div><div><h3>Methods</h3><p>This research utilizes data from the Adolescent Brain Cognitive Development (ABCD) study, a longitudinal project initiated in 2016 with a sample of 11,849 participants. It explores the links between residential stability, socioeconomic factors, stress, and emotional and behavioral outcomes using the Child Behavior Checklist (CBCL). Structural equation modeling was employed to analyze the data.</p></div><div><h3>Results findings</h3><p>indicate that higher household income, living in a household with married parents, and residing in areas with greater household incomes correlate with residential stability. In turn, residential stability is linked to lower levels of life stress and reduced substance use in the future. Furthermore, the impact of residential stability on substance uses and CBCL scores was entirely mediated by trauma exposure.</p></div><div><h3>Conclusions</h3><p>The findings advocate for the implementation of economic, social, and public policies aimed at fostering stable living environments for children and families to mitigate the emotional and behavioral challenges future generations may face. Enhancing socioeconomic status and supporting structures that promote married family living arrangements emerge as effective strategies to improve residential stability and the well-being of young people in the United States.</p></div>","PeriodicalId":100804,"journal":{"name":"Journal of Medicine, Surgery, and Public Health","volume":"2 ","pages":"Article 100084"},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949916X24000379/pdfft?md5=e4cd833cfc452a872f7ae6c6f840f67f&pid=1-s2.0-S2949916X24000379-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140122926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surgery represents a distinct medical specialization that necessitates direct interaction with patients and the ability to manage complications. Burn-out is defined as a syndrome arising from persistent workplace stress that has not been effectively addressed. The objective of this work was to assess the prevalence and factors associated with burn-out among practitioners managing abdominal surgical emergencies in Senegal. A descriptive and analytical cross-sectional study was conducted; the study included healthcare professionals (general practitioners, general surgeons, anesthesiologists, nurses) involved in the management of surgical emergencies across all hospitals in Senegal. A standardized assessment of perceived stress was conducted using the Maslach Burnout Inventory (MBI) in three domains: emotional exhaustion, depersonalization, and personal accomplishment. A multiple linear regression model was used to estimate the determinants of burn-out on the three subscales. A total of 186 observations were included in the study, for a response rate of 90.7%. The majority of participants were from the capital region of Dakar (44. 6%). There were 46 women (24. 7%) and 140 men (75. 3%). The mean age was 34 years 9 ±6.7 years, with a range of 24–59 years. The majority of participants were married (71%), followed by single individuals (26. 3%), divorced (2. 2%), and widowed (0. 5%). The majority of participants were physicians (80. 6%), followed by nurses (19. 4%). The most common medical specializations were general surgery (58.7%), anesthesia and resuscitation (22. 7%), and general medicine (18. 7%). Additionally, 46% of participants were in training (residency program). The predominant motivations included passion for the profession (75.3%), patient satisfaction (69. 9%), stimulating challenges (21%), and salary considerations (11. 8%). The overall prevalence of high burn-out (at least in one dimension) was 46.2%. A multiple linear regression model showed that the risk factors contributing to high burn-out were divorce status, being in training, and being motivated by stimulating challenges, salary considerations or passion for the profession. The protective factors were a positive perception of one's salary, a favorable physical work environment, and high-quality training. This study revealed an alarming prevalence of burn-out among surgical teams dealing with abdominal emergencies in Senegal. These findings call for immediate action to ensure the well-being of surgical teams and, by extension, the quality of healthcare delivery.
{"title":"Burn-out among practitioners managing abdominal surgical emergencies in Senegal","authors":"Abdourahmane Ndong , Lebem Togtoga , Mamadou Saidou Bah , Pape Djibril Ndoye , Jean Augustin Diegane Tine , Ibrahima Konaté , Khadim Niang","doi":"10.1016/j.glmedi.2024.100087","DOIUrl":"https://doi.org/10.1016/j.glmedi.2024.100087","url":null,"abstract":"<div><h3>Introduction</h3><p>Surgery represents a distinct medical specialization that necessitates direct interaction with patients and the ability to manage complications. Burn-out is defined as a syndrome arising from persistent workplace stress that has not been effectively addressed. The objective of this work was to assess the prevalence and factors associated with burn-out among practitioners managing abdominal surgical emergencies in Senegal. A descriptive and analytical cross-sectional study was conducted; the study included healthcare professionals (general practitioners, general surgeons, anesthesiologists, nurses) involved in the management of surgical emergencies across all hospitals in Senegal. A standardized assessment of perceived stress was conducted using the Maslach Burnout Inventory (MBI) in three domains: emotional exhaustion, depersonalization, and personal accomplishment. A multiple linear regression model was used to estimate the determinants of burn-out on the three subscales. A total of 186 observations were included in the study, for a response rate of 90.7%. The majority of participants were from the capital region of Dakar (44. 6%). There were 46 women (24. 7%) and 140 men (75. 3%). The mean age was 34 years 9 ±6.7 years, with a range of 24–59 years. The majority of participants were married (71%), followed by single individuals (26. 3%), divorced (2. 2%), and widowed (0. 5%). The majority of participants were physicians (80. 6%), followed by nurses (19. 4%). The most common medical specializations were general surgery (58.7%), anesthesia and resuscitation (22. 7%), and general medicine (18. 7%). Additionally, 46% of participants were in training (residency program). The predominant motivations included passion for the profession (75.3%), patient satisfaction (69. 9%), stimulating challenges (21%), and salary considerations (11. 8%). The overall prevalence of high burn-out (at least in one dimension) was 46.2%. A multiple linear regression model showed that the risk factors contributing to high burn-out were divorce status, being in training, and being motivated by stimulating challenges, salary considerations or passion for the profession. The protective factors were a positive perception of one's salary, a favorable physical work environment, and high-quality training. This study revealed an alarming prevalence of burn-out among surgical teams dealing with abdominal emergencies in Senegal. These findings call for immediate action to ensure the well-being of surgical teams and, by extension, the quality of healthcare delivery.</p></div>","PeriodicalId":100804,"journal":{"name":"Journal of Medicine, Surgery, and Public Health","volume":"2 ","pages":"Article 100087"},"PeriodicalIF":0.0,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949916X24000409/pdfft?md5=7b33aec927390670a315d742c5ab7dbb&pid=1-s2.0-S2949916X24000409-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140134478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-11DOI: 10.1016/j.glmedi.2024.100086
Aftab Ahmed , Fatima Bint Sajid , Zaib Un Nisa Mughal , Wajeeha Binte Sajid , Abdul Haseeb
This case report highlights a rare condition known as PANDAS (Pediatrics Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections), which is characterized by sudden-onset neuropsychiatric symptoms following a streptococcal infection. The report also describes the unusual occurrence of cerebellitis, an uncommon neurological manifestation involving inflammation of the cerebellum, along with symptoms of vomiting and cerebellitis in a 9-year-old patient. The patient exhibited sudden onset of obsessive-compulsive symptoms, tics, stomach pain, and signs of intestinal blockage, which led to cerebellar dysfunction upon neurological examination. Laboratory tests confirmed a recent streptococcal infection, suggesting a diagnosis of PANDAS, while imaging studies revealed inflammation in the cerebellum and intestinal obstruction. This case presents a challenge to our understanding of the pathophysiological processes underlying PANDAS and its relationship with gastrointestinal and cerebellar symptoms. The treatment plan included immunomodulatory therapy, antibiotics, and surgical intervention for the intestinal obstruction, which led to a gradual improvement in symptoms. The report underscores the importance of considering atypical manifestations of PANDAS and adopting a multidisciplinary approach for precise diagnosis and effective management in complex situations.
{"title":"PANDAS coexisting with gastrointestinal and cerebellar manifestation","authors":"Aftab Ahmed , Fatima Bint Sajid , Zaib Un Nisa Mughal , Wajeeha Binte Sajid , Abdul Haseeb","doi":"10.1016/j.glmedi.2024.100086","DOIUrl":"https://doi.org/10.1016/j.glmedi.2024.100086","url":null,"abstract":"<div><p>This case report highlights a rare condition known as PANDAS (Pediatrics Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections), which is characterized by sudden-onset neuropsychiatric symptoms following a streptococcal infection. The report also describes the unusual occurrence of cerebellitis, an uncommon neurological manifestation involving inflammation of the cerebellum, along with symptoms of vomiting and cerebellitis in a 9-year-old patient. The patient exhibited sudden onset of obsessive-compulsive symptoms, tics, stomach pain, and signs of intestinal blockage, which led to cerebellar dysfunction upon neurological examination. Laboratory tests confirmed a recent streptococcal infection, suggesting a diagnosis of PANDAS, while imaging studies revealed inflammation in the cerebellum and intestinal obstruction. This case presents a challenge to our understanding of the pathophysiological processes underlying PANDAS and its relationship with gastrointestinal and cerebellar symptoms. The treatment plan included immunomodulatory therapy, antibiotics, and surgical intervention for the intestinal obstruction, which led to a gradual improvement in symptoms. The report underscores the importance of considering atypical manifestations of PANDAS and adopting a multidisciplinary approach for precise diagnosis and effective management in complex situations.</p></div>","PeriodicalId":100804,"journal":{"name":"Journal of Medicine, Surgery, and Public Health","volume":"2 ","pages":"Article 100086"},"PeriodicalIF":0.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949916X24000392/pdfft?md5=7d5e660a7d19d7fe33e71aea05ff13bb&pid=1-s2.0-S2949916X24000392-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140134479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-11DOI: 10.1016/j.glmedi.2024.100085
Roshan Rambukwella , Leo D. Westbury , Cyrus Cooper , Nicholas C. Harvey , Elaine M. Dennison
Background
Poor self-rated health (SRH) has been shown to predict adverse health outcomes among older people, however these associations have traditionally only been considered at one point in the lifecourse, usually midlife or later. Here we examined lifecourse correlates of SRH in early, mid and later life, relating these to subsequent risk of mortality in a community-dwelling cohort.
Methods
2989 men and women from the Hertfordshire Cohort Study (HCS) were included in this study. The HCS was initially retrospective and linked contemporary health outcome data to early life data available from health ledgers but investigations from baseline (1998–2004, aged 59–73) onwards have been prospective. At baseline, participants completed an initial clinic visit, which included questionnaire assessment of SRH, reported as 'excellent', 'very good', 'good', 'fair', or 'poor'. Socioeconomic, lifestyle, mental health and demographic information was also collected. Deaths were recorded from baseline to 31/12/2018. Baseline characteristics in relation to SRH were examined using sex-stratified ordinal logistic regression; these factors were examined in relation to mortality using sex-stratified Cox regression. Statistically significant exposures were then included in sex-stratified mutually-adjusted models.
Results
In mutually-adjusted analysis, numerous contemporaneous correlates of poorer SRH in the seventh decade were identified and included obesity, lower physical activity, greater comorbidity and higher levels of depression among men and women. For example, odds ratios for being in a lower category of SRH were as follows: obese (BMI≥30) vs underweight/healthy (BMI<25) (men 1.60 (1.21, 2.11), women 1.65 (1.25, 2.17)) and per additional system medicated (men 1.62 (1.47, 1.77), women 1.53 (1.41, 1.66)). By contrast, factors earlier in the lifecourse (early growth, age left full-time education) were not associated with SRH in late adulthood. 36% of men and 26% of women died during follow-up. Hazard ratios (95% CI) for mortality per lower category of SRH were 1.22 (1.10,1.36) among men and 1.17 (1.01,1.35) among women after adjustment for age, BMI, smoking, physical activity, diet quality, education, home ownership status, comorbidity level and depression levels, suggesting residual confounding by other unrecorded factors that are related to SRH.
Conclusions
Poorer SRH in the seventh decade was a risk factor for mortality. Importantly modifiable adverse health behaviours in the seventh decade, such as low physical activity, were associated with poorer SRH and later mortality after adjustment for socioeconomic factors and comorbidity level. By contrast early growth and education were not related to later SRH. These data suggest that attention to lifestyle in late midlife may be associated with better SRH and subsequent health outcomes, highlighting the value of interven
{"title":"Lifecourse correlates of self-rated health and associations with subsequent mortality: findings from the Hertfordshire Cohort Study","authors":"Roshan Rambukwella , Leo D. Westbury , Cyrus Cooper , Nicholas C. Harvey , Elaine M. Dennison","doi":"10.1016/j.glmedi.2024.100085","DOIUrl":"https://doi.org/10.1016/j.glmedi.2024.100085","url":null,"abstract":"<div><h3>Background</h3><p>Poor self-rated health (SRH) has been shown to predict adverse health outcomes among older people, however these associations have traditionally only been considered at one point in the lifecourse, usually midlife or later. Here we examined lifecourse correlates of SRH in early, mid and later life, relating these to subsequent risk of mortality in a community-dwelling cohort.</p></div><div><h3>Methods</h3><p>2989 men and women from the Hertfordshire Cohort Study (HCS) were included in this study. The HCS was initially retrospective and linked contemporary health outcome data to early life data available from health ledgers but investigations from baseline (1998–2004, aged 59–73) onwards have been prospective. At baseline, participants completed an initial clinic visit, which included questionnaire assessment of SRH, reported as 'excellent', 'very good', 'good', 'fair', or 'poor'. Socioeconomic, lifestyle, mental health and demographic information was also collected. Deaths were recorded from baseline to 31/12/2018. Baseline characteristics in relation to SRH were examined using sex-stratified ordinal logistic regression; these factors were examined in relation to mortality using sex-stratified Cox regression. Statistically significant exposures were then included in sex-stratified mutually-adjusted models.</p></div><div><h3>Results</h3><p>In mutually-adjusted analysis, numerous contemporaneous correlates of poorer SRH in the seventh decade were identified and included obesity, lower physical activity, greater comorbidity and higher levels of depression among men and women. For example, odds ratios for being in a lower category of SRH were as follows: obese (BMI≥30) vs underweight/healthy (BMI<25) (men 1.60 (1.21, 2.11), women 1.65 (1.25, 2.17)) and per additional system medicated (men 1.62 (1.47, 1.77), women 1.53 (1.41, 1.66)). By contrast, factors earlier in the lifecourse (early growth, age left full-time education) were not associated with SRH in late adulthood. 36% of men and 26% of women died during follow-up. Hazard ratios (95% CI) for mortality per lower category of SRH were 1.22 (1.10,1.36) among men and 1.17 (1.01,1.35) among women after adjustment for age, BMI, smoking, physical activity, diet quality, education, home ownership status, comorbidity level and depression levels, suggesting residual confounding by other unrecorded factors that are related to SRH.</p></div><div><h3>Conclusions</h3><p>Poorer SRH in the seventh decade was a risk factor for mortality. Importantly modifiable adverse health behaviours in the seventh decade, such as low physical activity, were associated with poorer SRH and later mortality after adjustment for socioeconomic factors and comorbidity level. By contrast early growth and education were not related to later SRH. These data suggest that attention to lifestyle in late midlife may be associated with better SRH and subsequent health outcomes, highlighting the value of interven","PeriodicalId":100804,"journal":{"name":"Journal of Medicine, Surgery, and Public Health","volume":"2 ","pages":"Article 100085"},"PeriodicalIF":0.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949916X24000380/pdfft?md5=1982fcf2e137e239a5cb51cfad66ae44&pid=1-s2.0-S2949916X24000380-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140138431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-10DOI: 10.1016/j.glmedi.2024.100083
Ahmet Necati Sanli
Gestational gigantomastia is a sudden and rapidly developing unilateral or bilateral excessive breast enlargement during pregnancy. In this case report, we aimed to present a 27-year-old female patient who presented with the complaint of unilateral breast enlargement while she was 7 months pregnant in her second pregnancy and diagnosed with gestational gigantomastia, with clinical and treatment features. Since it is very rare, it may cause difficulties for clinicians in differential diagnosis. Although clinical and examination features suggest malignant or inflammatory processes, it is easy to exclude with radiological imaging methods. Medical or surgical treatment methods should be applied before delivery, as they may cause both psychological and physical deterioration, breast pain, or life-threatening complications such as ulceration-hematoma in the breast for the patient. Malignant and inflammatory processes should be ruled out in the case of rapidly developing breast enlargement during pregnancy, and medical or surgical treatment options should be performed based on the patient's preferences and the gestational week.
{"title":"Unilateral gestational gigantomastia in the third trimester","authors":"Ahmet Necati Sanli","doi":"10.1016/j.glmedi.2024.100083","DOIUrl":"https://doi.org/10.1016/j.glmedi.2024.100083","url":null,"abstract":"<div><p>Gestational gigantomastia is a sudden and rapidly developing unilateral or bilateral excessive breast enlargement during pregnancy. In this case report, we aimed to present a 27-year-old female patient who presented with the complaint of unilateral breast enlargement while she was 7 months pregnant in her second pregnancy and diagnosed with gestational gigantomastia, with clinical and treatment features. Since it is very rare, it may cause difficulties for clinicians in differential diagnosis. Although clinical and examination features suggest malignant or inflammatory processes, it is easy to exclude with radiological imaging methods. Medical or surgical treatment methods should be applied before delivery, as they may cause both psychological and physical deterioration, breast pain, or life-threatening complications such as ulceration-hematoma in the breast for the patient. Malignant and inflammatory processes should be ruled out in the case of rapidly developing breast enlargement during pregnancy, and medical or surgical treatment options should be performed based on the patient's preferences and the gestational week.</p></div>","PeriodicalId":100804,"journal":{"name":"Journal of Medicine, Surgery, and Public Health","volume":"2 ","pages":"Article 100083"},"PeriodicalIF":0.0,"publicationDate":"2024-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949916X24000367/pdfft?md5=33ad4c17d5ae729861e6737ff2130607&pid=1-s2.0-S2949916X24000367-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140122927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-02DOI: 10.1016/j.glmedi.2024.100080
Jayeshkumar Kanani, Mohammed Iliyas Sheikh
Heterotopic ossification (HO) is defined as the development of lamellar bone growth in non-osseous tissues, such as muscles and tendons around major joints such as hip, elbow, knee, and shoulder. This article explores a unique case of heterotopic ossification (HO) on the outer surface of the spleen, presenting a rare and atypical manifestation of lamellar bone growth. The patient was a 50-year-old male who died under unclear circumstances and requested a medico-legal autopsy. Surprisingly, autopsy examination revealed a substantial, massive bone-like structure firmly attached to the spleen. Further histopathological examination revealed gamma gandy bodies, fibrosis, chronic venous congestion, and medial calcific sclerosis in the blood vessels of the spleen. The cut section of the bony structure showed areas of congestion, heterotopic ossification, and patchy calcification. The absence of a history of trauma adds complexity to the case, as ossification typically manifests in skeletal tissues. These findings underscore the rarity of HO in this anatomical location and emphasize the need for further research to unravel its causes, implications, and potential therapeutic interventions. This unique presentation highlights the importance of understanding heterotopic ossification intricacies, exploring organ-specific functions, and recognizing the role of autopsies in understanding unusual medical phenomena.
{"title":"A puzzling case: A unique presentation of massive heterotopic ossification on the Spleen’s outer surface","authors":"Jayeshkumar Kanani, Mohammed Iliyas Sheikh","doi":"10.1016/j.glmedi.2024.100080","DOIUrl":"https://doi.org/10.1016/j.glmedi.2024.100080","url":null,"abstract":"<div><p>Heterotopic ossification (HO) is defined as the development of lamellar bone growth in non-osseous tissues, such as muscles and tendons around major joints such as hip, elbow, knee, and shoulder. This article explores a unique case of heterotopic ossification (HO) on the outer surface of the spleen, presenting a rare and atypical manifestation of lamellar bone growth. The patient was a 50-year-old male who died under unclear circumstances and requested a medico-legal autopsy. Surprisingly, autopsy examination revealed a substantial, massive bone-like structure firmly attached to the spleen. Further histopathological examination revealed gamma gandy bodies, fibrosis, chronic venous congestion, and medial calcific sclerosis in the blood vessels of the spleen. The cut section of the bony structure showed areas of congestion, heterotopic ossification, and patchy calcification. The absence of a history of trauma adds complexity to the case, as ossification typically manifests in skeletal tissues. These findings underscore the rarity of HO in this anatomical location and emphasize the need for further research to unravel its causes, implications, and potential therapeutic interventions. This unique presentation highlights the importance of understanding heterotopic ossification intricacies, exploring organ-specific functions, and recognizing the role of autopsies in understanding unusual medical phenomena.</p></div>","PeriodicalId":100804,"journal":{"name":"Journal of Medicine, Surgery, and Public Health","volume":"2 ","pages":"Article 100080"},"PeriodicalIF":0.0,"publicationDate":"2024-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949916X24000331/pdfft?md5=a8dcca17ff166416941e0d75c4832d5f&pid=1-s2.0-S2949916X24000331-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140031011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-02DOI: 10.1016/j.glmedi.2024.100082
Kane Darling , Brandon Wilkinson , Cheyenne Wong , Angela MacFarlane , Camille Brummett , Isain Zapata
Background
With growing concerns on the worsening opioid epidemic and provider hesitation for opioid use, opioid-sparing treatment regimens are being introduced such as ketorolac administration. The primary aims of this study are to compare the safety and efficacy of ketorolac to fentanyl in the prehospital setting and to determine ketorolac's potential as a practical alternative analgesic.
Methods
A retrospective chart review of patient encounters obtained from a prehospital emergency medical services agency in New Mexico was conducted to evaluate the safety and efficacy of ketorolac vs. fentanyl in the prehospital setting. Primary outcomes assessed were the reported medication complications, initial pain, last pain, and pain reduction on a Numerical Rating Scale. Data was evaluated using unadjusted and adjusted (age, gender, and weight of the patient) models.
Results
A total of 4102 records were evaluated (3182 fentanyl cases vs. 920 ketorolac cases). No significant differences in initial, last pain or pain reduction were seen in unadjusted models and for age, gender, or weight adjusted models. However, adjusted models displayed a difference in the number of complications that occurred while all cases of medication complications occurred within the fentanyl group (64 occurrences, P<0.0001). Among the complications seen, nausea and hypoxia are the most frequent with 40.6 and 29.7% of occurrences respectively).
Conclusion
Findings suggest that ketorolac is both effective and safe in the prehospital environment when compared to fentanyl. These findings encourage prehospital agencies to adopt opioid-sparing treatment protocols to encourage increased treatment of pain without potentiating the current opioid epidemic.
{"title":"Ketorolac vs. Fentanyl: A retrospective chart review of analgesia in the prehospital environment","authors":"Kane Darling , Brandon Wilkinson , Cheyenne Wong , Angela MacFarlane , Camille Brummett , Isain Zapata","doi":"10.1016/j.glmedi.2024.100082","DOIUrl":"https://doi.org/10.1016/j.glmedi.2024.100082","url":null,"abstract":"<div><h3>Background</h3><p>With growing concerns on the worsening opioid epidemic and provider hesitation for opioid use, opioid-sparing treatment regimens are being introduced such as ketorolac administration. The primary aims of this study are to compare the safety and efficacy of ketorolac to fentanyl in the prehospital setting and to determine ketorolac's potential as a practical alternative analgesic.</p></div><div><h3>Methods</h3><p>A retrospective chart review of patient encounters obtained from a prehospital emergency medical services agency in New Mexico was conducted to evaluate the safety and efficacy of ketorolac vs. fentanyl in the prehospital setting. Primary outcomes assessed were the reported medication complications, initial pain, last pain, and pain reduction on a Numerical Rating Scale. Data was evaluated using unadjusted and adjusted (age, gender, and weight of the patient) models.</p></div><div><h3>Results</h3><p>A total of 4102 records were evaluated (3182 fentanyl cases vs. 920 ketorolac cases). No significant differences in initial, last pain or pain reduction were seen in unadjusted models and for age, gender, or weight adjusted models. However, adjusted models displayed a difference in the number of complications that occurred while all cases of medication complications occurred within the fentanyl group (64 occurrences, P<0.0001). Among the complications seen, nausea and hypoxia are the most frequent with 40.6 and 29.7% of occurrences respectively).</p></div><div><h3>Conclusion</h3><p>Findings suggest that ketorolac is both effective and safe in the prehospital environment when compared to fentanyl. These findings encourage prehospital agencies to adopt opioid-sparing treatment protocols to encourage increased treatment of pain without potentiating the current opioid epidemic.</p></div>","PeriodicalId":100804,"journal":{"name":"Journal of Medicine, Surgery, and Public Health","volume":"2 ","pages":"Article 100082"},"PeriodicalIF":0.0,"publicationDate":"2024-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949916X24000355/pdfft?md5=2f325625a9381393806432e639e38e1f&pid=1-s2.0-S2949916X24000355-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140042198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-02DOI: 10.1016/j.glmedi.2024.100081
Sirwan Khalid Ahmed , Safin Hussein , Karzan Qurbani , Radhwan Hussein Ibrahim , Abdulmalik Fareeq , Kochr Ali Mahmood , Mona Gamal Mohamed
Antimicrobial resistance (AMR) is a critical global health issue driven by antibiotic misuse and overuse in various sectors, leading to the emergence of resistant microorganisms. The history of AMR dates back to the discovery of penicillin, with the rise of multidrug-resistant pathogens posing significant challenges to healthcare systems worldwide. The misuse of antibiotics in human and animal health, as well as in agriculture, contributes to the spread of resistance genes, creating a "Silent Pandemic" that could surpass other causes of mortality by 2050. AMR affects both humans and animals, with resistant pathogens posing challenges in treating infections. Various mechanisms, such as enzymatic modification and biofilm formation, enable microbes to withstand the effects of antibiotics. The lack of effective antibiotics threatens routine medical procedures and could lead to millions of deaths annually if left unchecked. The economic impact of AMR is substantial, with projected losses in the trillions of dollars and significant financial burdens on healthcare systems and agriculture. Artificial intelligence is being explored as a tool to combat AMR by improving diagnostics and treatment strategies, although challenges such as data quality and algorithmic biases exist. To address AMR effectively, a One Health approach that considers human, animal, and environmental factors is crucial. This includes enhancing surveillance systems, promoting stewardship programs, and investing in research and development for new antimicrobial options. Public awareness, education, and international collaboration are essential for combating AMR and preserving the efficacy of antibiotics for future generations.
抗菌药耐药性(AMR)是一个严重的全球健康问题,其原因是各行各业滥用和过度使用抗生素,导致耐药微生物的出现。AMR 的历史可以追溯到青霉素的发现,随着耐多药病原体的增多,AMR 给全球医疗保健系统带来了重大挑战。抗生素在人类和动物健康以及农业中的滥用助长了抗药性基因的传播,造成了一种 "无声的大流行",到 2050 年可能会超过其他致死原因。AMR 对人类和动物都有影响,抗药性病原体给治疗感染带来了挑战。酶修饰和生物膜形成等各种机制使微生物能够抵御抗生素的作用。缺乏有效的抗生素威胁着常规医疗程序,如果任其发展,每年可能导致数百万人死亡。AMR 对经济的影响是巨大的,预计将造成数万亿美元的损失,并给医疗保健系统和农业带来沉重的经济负担。尽管存在数据质量和算法偏差等挑战,但人们正在探索将人工智能作为一种工具,通过改进诊断和治疗策略来应对 AMR。要有效解决 AMR 问题,必须采取综合考虑人类、动物和环境因素的 "一体健康 "方法。这包括加强监测系统、推广管理计划以及投资研发新的抗菌药物。公众意识、教育和国际合作对于抗击 AMR 和为子孙后代保护抗生素的有效性至关重要。
{"title":"Antimicrobial resistance: Impacts, challenges, and future prospects","authors":"Sirwan Khalid Ahmed , Safin Hussein , Karzan Qurbani , Radhwan Hussein Ibrahim , Abdulmalik Fareeq , Kochr Ali Mahmood , Mona Gamal Mohamed","doi":"10.1016/j.glmedi.2024.100081","DOIUrl":"https://doi.org/10.1016/j.glmedi.2024.100081","url":null,"abstract":"<div><p>Antimicrobial resistance (AMR) is a critical global health issue driven by antibiotic misuse and overuse in various sectors, leading to the emergence of resistant microorganisms. The history of AMR dates back to the discovery of penicillin, with the rise of multidrug-resistant pathogens posing significant challenges to healthcare systems worldwide. The misuse of antibiotics in human and animal health, as well as in agriculture, contributes to the spread of resistance genes, creating a \"Silent Pandemic\" that could surpass other causes of mortality by 2050. AMR affects both humans and animals, with resistant pathogens posing challenges in treating infections. Various mechanisms, such as enzymatic modification and biofilm formation, enable microbes to withstand the effects of antibiotics. The lack of effective antibiotics threatens routine medical procedures and could lead to millions of deaths annually if left unchecked. The economic impact of AMR is substantial, with projected losses in the trillions of dollars and significant financial burdens on healthcare systems and agriculture. Artificial intelligence is being explored as a tool to combat AMR by improving diagnostics and treatment strategies, although challenges such as data quality and algorithmic biases exist. To address AMR effectively, a One Health approach that considers human, animal, and environmental factors is crucial. This includes enhancing surveillance systems, promoting stewardship programs, and investing in research and development for new antimicrobial options. Public awareness, education, and international collaboration are essential for combating AMR and preserving the efficacy of antibiotics for future generations.</p></div>","PeriodicalId":100804,"journal":{"name":"Journal of Medicine, Surgery, and Public Health","volume":"2 ","pages":"Article 100081"},"PeriodicalIF":0.0,"publicationDate":"2024-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949916X24000343/pdfft?md5=01f37ccfb21954681f5e6615fda255bf&pid=1-s2.0-S2949916X24000343-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140063111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-29DOI: 10.1016/j.glmedi.2024.100079
Jessica Schmerler , Sarah Rapaport , Alexandra M. Dunham , Sophia Strike , E. Gene Deune , Dawn LaPorte
Compartment syndrome (CS) is an orthopaedic emergency that can result in vascular and neurologic compromise and necrosis due to increased pressure in an anatomic compartment, commonly the lower leg or forearm. The purpose of this case series study was to demonstrate that CS is a rare but serious complication for which physicians should have a low threshold for suspicion after transradial access procedures. We present a series of five patients who underwent fasciotomy for upper extremity CS in the setting of recent transradial access at a large, busy, tertiary academic center from 1/1/2015–12/31/2022. Cases were identified retrospectively from departmental case logs and data were collected by manual chart review. Patient demographics and comorbidities, as well as details of transradial access procedures and anticoagulation use were recorded. The outcome variables collected included time from access removal to hand surgery consult, symptoms present at the time of the consult, procedural details, and postoperative outcomes. Of the five cases presented, three underwent transradial access for percutaneous coronary intervention (PCI) and two for invasive blood pressure monitoring. Four of the five patients received systemic anticoagulation prior to or during transradial access, and the fifth received anticoagulation after the procedure. All five patients presented with large forearm hematomas at the time of initial consult, and three of the five were found at the time of fasciotomies to have radial artery lacerations. Two patients had subsequent surgeries after the primary fasciotomy, and one patient had residual neurologic symptoms. The results point to several key takeaways regarding CS in the setting of transradial access, including association with receipt of systemic anticoagulation, presence of forearm hematomas as potential markers for radial artery laceration, and multiple arterial lacerations as potential risk factors for worse post-fasciotomy outcomes. To our knowledge, this is the largest case series describing this specific, devasting complication of transradial access. Hand surgeons should be aware of this rare etiology of compartment syndrome so that they may more quickly recognize and respond to this potential complication.
{"title":"Compartment syndrome as a complication of transradial access","authors":"Jessica Schmerler , Sarah Rapaport , Alexandra M. Dunham , Sophia Strike , E. Gene Deune , Dawn LaPorte","doi":"10.1016/j.glmedi.2024.100079","DOIUrl":"https://doi.org/10.1016/j.glmedi.2024.100079","url":null,"abstract":"<div><p>Compartment syndrome (CS) is an orthopaedic emergency that can result in vascular and neurologic compromise and necrosis due to increased pressure in an anatomic compartment, commonly the lower leg or forearm. The purpose of this case series study was to demonstrate that CS is a rare but serious complication for which physicians should have a low threshold for suspicion after transradial access procedures. We present a series of five patients who underwent fasciotomy for upper extremity CS in the setting of recent transradial access at a large, busy, tertiary academic center from 1/1/2015–12/31/2022. Cases were identified retrospectively from departmental case logs and data were collected by manual chart review. Patient demographics and comorbidities, as well as details of transradial access procedures and anticoagulation use were recorded. The outcome variables collected included time from access removal to hand surgery consult, symptoms present at the time of the consult, procedural details, and postoperative outcomes. Of the five cases presented, three underwent transradial access for percutaneous coronary intervention (PCI) and two for invasive blood pressure monitoring. Four of the five patients received systemic anticoagulation prior to or during transradial access, and the fifth received anticoagulation after the procedure. All five patients presented with large forearm hematomas at the time of initial consult, and three of the five were found at the time of fasciotomies to have radial artery lacerations. Two patients had subsequent surgeries after the primary fasciotomy, and one patient had residual neurologic symptoms. The results point to several key takeaways regarding CS in the setting of transradial access, including association with receipt of systemic anticoagulation, presence of forearm hematomas as potential markers for radial artery laceration, and multiple arterial lacerations as potential risk factors for worse post-fasciotomy outcomes. To our knowledge, this is the largest case series describing this specific, devasting complication of transradial access. Hand surgeons should be aware of this rare etiology of compartment syndrome so that they may more quickly recognize and respond to this potential complication.</p></div><div><h3>Level of evidence</h3><p>IV.</p></div>","PeriodicalId":100804,"journal":{"name":"Journal of Medicine, Surgery, and Public Health","volume":"2 ","pages":"Article 100079"},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949916X2400032X/pdfft?md5=2e76e243b16215bf1b8e31c09018c622&pid=1-s2.0-S2949916X2400032X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140000066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}