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The impact of disordered eating and eating behavior on weight loss after sleeve gastrectomy in Egyptian adolescents 饮食失调和饮食行为对埃及青少年袖式胃切除术后体重减轻的影响
Pub Date : 2025-09-09 DOI: 10.1016/j.obpill.2025.100207
Mohey Elbanna , Amany Falah , Ahmed Magdy Hafez

Background

Bariatric surgery is the most effective treatment for obesity in Adolescents. However, disordered eating is frequent in this population. Several studies found that disordered eating affects weight loss after bariatric surgery. The aim of this study was to find out the impact of disordered eating on weight loss in Egyptian adolescents two years after sleeve gastrectomy.

Methods

This is a retrospective cohort study conducted at Ain Shams University Hospitals from March 2020 to March 2024. It included 47 adolescents with obesity who underwent laparoscopic sleeve gastrectomy (LSG) two years before. Their age was 16.2 ± 0.67 years (range 14.5 – 17.8 years old). Their body mass indices were above 99th percentile for age and sex with or without comorbidities. They had a mean BMI of 39.9 kg/m² (range: 36.9 – 54.3 kg/m²). Patients with psychiatric illnesses and eating disorders were excluded. Patients were recruited after completion of two years of follow up for weight loss. Weight loss was evaluated by total weight loss % (TWL%). Disordered eating was detected by the Arabic version of EDE-Q v.6.0, and a global score of > 2.5 was considered positive. TWL% was correlated with EDE-Q score.

Results

After two years, the mean TWL% was 27.5% ± 7.7%. Nineteen patients (40.4%) had EDE-Q score more than 2.5. The EDE-Q positive patients had a mean %TWL of 25.7% ± 4.8%, while EDE-Q negative patients had a mean %TWL of 30.5% ± 6.2%. The difference is statistically significant.

Conclusion

We conclude that the outcome of sleeve gastrectomy in adolescents is affected by their eating behavior as soon as the restrictive effect of the operations subsides.
背景:减肥手术是治疗青少年肥胖最有效的方法。然而,饮食失调在这一人群中很常见。几项研究发现,饮食失调会影响减肥手术后的体重减轻。本研究的目的是找出埃及青少年在袖胃切除术两年后饮食失调对体重减轻的影响。方法回顾性队列研究于2020年3月至2024年3月在艾因沙姆斯大学附属医院进行。它包括47名肥胖的青少年,他们在两年前接受了腹腔镜袖胃切除术(LSG)。年龄16.2±0.67岁(14.5 ~ 17.8岁)。不论有无合并症,他们的体重指数均在年龄和性别的第99百分位以上。他们的平均BMI为39.9 kg/m²(范围:36.9 - 54.3 kg/m²)。排除有精神疾病和饮食失调的患者。患者在完成两年的减肥随访后被招募。以总减重% (TWL%)评价体重减轻。进食障碍采用阿拉伯语版ed - q v.6.0进行检测,整体得分为>; 2.5为阳性。TWL%与ed - q评分相关。结果术后2年TWL%平均值为27.5%±7.7%。ed - q评分大于2.5的患者19例(40.4%)。ed - q阳性患者的平均%TWL为25.7%±4.8%,ed - q阴性患者的平均%TWL为30.5%±6.2%。这一差异在统计学上是显著的。结论青少年袖胃切除术后,一旦手术限制作用消退,其饮食行为就会影响手术效果。
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引用次数: 0
Dietary supplement considerations during glucagon-like Peptide-1 receptor agonist treatment: A narrative review 胰高血糖素样肽-1受体激动剂治疗期间膳食补充剂的考虑:叙述性回顾
Pub Date : 2025-09-08 DOI: 10.1016/j.obpill.2025.100209
Brittany V.B. Johnson, Mary Milstead, Rachel Kreider, Rachel Jones

Background

Recent advancements with Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) result in approximately 15 % or more weight reduction. Scientific research addressing specific nutritional concerns with GLP-1RA are still emerging. While some guidelines currently exist for nutritional considerations, they are largely focused on side effect management and providing basic dietary guidance during GLP-1RA.

Methods

This narrative review aims to provide practical evidence-based considerations for dietary supplementation to help optimize health outcomes while using GLP-1RA. We reviewed available literature of dietary supplementation interventions among individuals with obesity, weight loss clinical trials, and adiposity-related complications to help guide clinicians on potentially advantageous supplementation.

Results

Robust data from meta-analyses provides justification for a variety of dietary supplements that can support the unintended consequences of GLP-1RA treatments. Multivitamins are recommended to address micronutrient insufficiencies as determined by individual deficiencies and suboptimal intake. Protein supplements can help individuals meet daily protein intake recommendations of 1.2–2.0 g/kg/d. When combined with resistance training, whey protein can help preserve lean body mass during weight loss, with additional strength benefits from creatine monohydrate and β-Hydroxy β-Methylbutyrate supplementation. Antioxidants and anti-inflammatory nutrients can mitigate oxidative stress and inflammation. Fiber and probiotics can improve bowel regularity and mitigate side effects.

Conclusion

Healthcare providers play an active role in supporting their patients with comprehensive obesity treatment. Guidance should focus on improving their long-term health and potentially mitigating unintended consequences. Optimizing nutrient intakes with therapeutic doses of dietary supplements may enhance outcomes when used alongside GLP-1RA, such as increasing nutrient status, retaining lean mass, reducing oxidative stress and inflammation, and improving gastrointestinal health.
胰高血糖素样肽-1受体激动剂(GLP-1RA)的最新进展导致大约15%或更多的体重减轻。与GLP-1RA有关的特定营养问题的科学研究仍在兴起。虽然目前存在一些营养方面的指南,但它们主要集中在副作用管理和提供GLP-1RA期间的基本饮食指导。方法本综述旨在为膳食补充剂提供实用的循证考虑,以帮助在使用GLP-1RA时优化健康结果。我们回顾了现有的关于膳食补充剂干预肥胖个体、减肥临床试验和肥胖相关并发症的文献,以帮助指导临床医生选择可能有利的补充剂。结果来自荟萃分析的可靠数据为各种膳食补充剂提供了理由,这些膳食补充剂可以支持GLP-1RA治疗的意外后果。多种维生素被推荐用于解决由个体缺乏和次优摄入量决定的微量营养素缺乏。蛋白质补充剂可以帮助个人达到每日蛋白质摄入量推荐值1.2-2.0 g/kg/d。当与阻力训练相结合时,乳清蛋白可以在减肥期间帮助保持瘦体重,并从肌酸一水和β-羟基β-甲基丁酸补充剂中获得额外的力量益处。抗氧化剂和抗炎营养素可以减轻氧化应激和炎症。纤维和益生菌可以改善肠道的规律性,减轻副作用。结论医护人员在支持患者进行肥胖综合治疗方面发挥着积极作用。指导应侧重于改善他们的长期健康和可能减轻意外后果。当与GLP-1RA一起使用时,优化营养摄入和治疗剂量的膳食补充剂可能会提高结果,如增加营养状况,保持瘦质量,减少氧化应激和炎症,改善胃肠道健康。
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引用次数: 0
The relationship between obesity and serum calcium level in a sample of Syrian people a cross sectional study 肥胖与叙利亚人血钙水平的关系横断面研究
Pub Date : 2025-09-02 DOI: 10.1016/j.obpill.2025.100208
Ola Faleh, Zaynab Alourfi

Introduction

Calcium is one of the most important elements in the human body playing a crucial role in various physiological functions. Its serum levels might be influenced by multiple factors. Obesity is a prevalent disease worldwide, and many studies have explored the relationship between obesity and serum calcium levels. This study aimed to investigate the association between Body Mass Index (BMI) and serum calcium.

Material and method

This cross-sectional study conducted at the National University Hospital between 2023 and 2024 involved 206 participants. Serum calcium levels were measured. A fasting morning blood sample was collected from each subject, and all tests were performed at The National University Hospital.

Result

The analysis showed no significant association between BMI and serum calcium levels, nor between age and serum calcium. However, after adjusting for age, the relationship between BMI and serum calcium strengthened and reached statistical significance, revealing an inverse correlation. This suggests that age acted as a partial confounding variable in the initial assessment.

Conclusion

While the initial findings of this cross-sectional study initially revealed no significant relationship between body mass index (BMI) and serum calcium, after adjusting for age, an inverse relationship was found between BMI and serum calcium, with higher BMI associated with lower serum calcium levels.
钙是人体中最重要的元素之一,在各种生理功能中起着至关重要的作用。其血清水平可能受多种因素影响。肥胖是一种世界性的普遍疾病,许多研究探讨了肥胖与血钙水平之间的关系。本研究旨在探讨身体质量指数(BMI)与血清钙的关系。材料和方法这项横断面研究于2023年至2024年在国立大学医院进行,涉及206名参与者。测定血清钙水平。从每个受试者身上采集空腹血液样本,并在国立大学医院进行所有测试。结果BMI与血钙无显著相关性,年龄与血钙无显著相关性。然而,在调整年龄后,BMI与血清钙的关系增强并达到统计学意义,呈负相关。这表明在最初的评估中,年龄是一个部分的混杂变量。虽然这项横断面研究的初步结果最初显示体重指数(BMI)和血清钙之间没有显著关系,但在调整年龄后,BMI和血清钙之间呈负相关,BMI越高,血清钙水平越低。
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引用次数: 0
Evaluating the long-term effectiveness of a structured telehealth obesity program in children and adolescents: A retrospective matched-control study 评估儿童和青少年结构化远程健康肥胖项目的长期有效性:一项回顾性匹配对照研究
Pub Date : 2025-08-29 DOI: 10.1016/j.obpill.2025.100206
Nora Struckmeyer , Torben Biester , Chantal Weiner , Evelin Sadeghian , Cathrin Guntermann , Laura Galuschka , Kisa von Stuelpnagel , Jantje Weiskorn , Kerstin Kapitzke , Karin Lange , Thomas Danne , Rebecca Toenne , Felix Reschke

Background

Childhood obesity is a growing global health crisis, driven by poor diet, reduced physical activity, and psychosocial distress. The COVID-19 pandemic amplified these factors, contributing to rising BMI and impaired health-related quality of life (HrQoL). Telehealth offers a promising, scalable modality to deliver multimodal obesity care. This study evaluated the long-term effectiveness of a structured pediatric telehealth intervention compared to historical in-person treatment.

Methods

This retrospective cohort study analyzed data from 237 children and adolescents with obesity treated at a single academic center. Between 2020 and 2022, 117 participants received a 12-month structured lifestyle intervention via telehealth. A historical cohort (n = 120; 2017–2019) received the same intervention in person. Clinical outcomes were assessed at baseline and after 12 months; the telehealth group was additionally followed up at 24 and 36 months. Primary outcome was change in BMI standard deviation score (BMI SDS). Secondary outcomes included physical fitness (6-min walk test), insulin resistance (HOMA index), lipid profile, dietary behavior (K-FFL), eating regulation (K-FEV), and HrQoL (KINDL-R).

Results

Both groups achieved significant reductions in BMI SDS after 12 months, with sustained improvements in the telehealth group through 36 months (Δ = −0.18; p < 0.05). Physical performance and HOMA index improved in both cohorts. Telehealth participants showed greater improvements in healthy dietary behavior, cognitive appetite regulation, and Health-related quality of life HrQoL, especially in emotional and family domains. No adverse events occurred; adherence exceeded 85 %.

Conclusion

A structured telehealth lifestyle intervention is safe, effective, and sustainable for pediatric obesity management. These findings support telehealth as a clinically viable and sustainable model for pediatric obesity care, recognizing that both weight reduction and weight stabilization may contribute to improved long-term outcomes.
儿童肥胖是一种日益严重的全球健康危机,其原因是饮食不良、身体活动减少和社会心理困扰。COVID-19大流行放大了这些因素,导致BMI上升和健康相关生活质量(HrQoL)受损。远程医疗提供了一种有前途的、可扩展的方式来提供多模式的肥胖护理。本研究评估了结构化儿科远程医疗干预与历史现场治疗的长期有效性。方法本回顾性队列研究分析了在单一学术中心接受治疗的237例肥胖儿童和青少年的数据。在2020年至2022年期间,117名参与者通过远程医疗接受了为期12个月的结构化生活方式干预。历史队列(n = 120; 2017-2019)接受相同的亲自干预。在基线和12个月后评估临床结果;远程医疗组分别在第24个月和第36个月进行随访。主要结局为BMI标准偏差评分(BMI SDS)的变化。次要结局包括身体健康(6分钟步行测试)、胰岛素抵抗(HOMA指数)、血脂、饮食行为(K-FFL)、饮食调节(K-FEV)和HrQoL (KINDL-R)。结果两组在12个月后BMI SDS均显著降低,远程医疗组持续改善36个月(Δ = - 0.18; p < 0.05)。两组患者的身体表现和HOMA指数均有改善。远程医疗参与者在健康饮食行为、认知食欲调节和健康相关生活质量HrQoL方面表现出更大的改善,尤其是在情感和家庭领域。无不良事件发生;依从性超过85%。结论结构化的远程健康生活方式干预治疗儿童肥胖安全、有效、可持续。这些发现支持远程医疗作为临床可行和可持续的儿童肥胖护理模式,认识到体重减轻和体重稳定可能有助于改善长期结果。
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引用次数: 0
Application of nutrition interventions with GLP-1 based therapies: A narrative review of the challenges and solutions 基于GLP-1疗法的营养干预的应用:挑战和解决方案的叙述性回顾
Pub Date : 2025-08-28 DOI: 10.1016/j.obpill.2025.100205
Angela Fitch , Linda Gigliotti , Harold Edward Bays

Background

Obesity is a heterogeneous systemic chronic disease associated with excess adiposity and a complex etiology and is increasing in prevalence worldwide. Initially used to treat type 2 diabetes mellitus, glucagon-like peptide-1 (GLP-1) based therapies are now widely prescribed for individuals with overweight and obesity as an adjunct to a reduced-calorie diet and increased physical activity. However, despite their impressive weight reduction capabilities, many patients on GLP-1 based therapies do not receive appropriate nutrition advice and struggle to maintain their weight reduction.

Methods

This narrative review explores and summarizes existing literature on the challenges associated with nutrition intake in people with obesity taking GLP-1 based therapies and practical applications of nutrition and lifestyle interventions for the management of these individuals to ensure their best long-term health outcomes.

Results

Delivering optimal nutrition management to people with obesity treated with GLP-1 based therapies presents healthcare providers with many challenges including addressing the impact of obesity and weight reduction on body composition (particularly muscle mass loss and risk of sarcopenic obesity), and poor nutrition. Physicians should work with dietitians and other healthcare providers to deliver comprehensive lifestyle counselling that is patient-centered, aligning with the needs and preferences of the individual. This should include advice on: timely and appropriate nutrition that centers on adequate macronutrient, micronutrient and fluid intake, particularly increased protein intake alongside resistance training for the preservation of muscle mass; mental health; sleep hygiene, physical activity; and medication adherence and persistence. Evidence-based nutrition guidelines can also provide an important framework for healthcare professionals, helping to ensure nutrition advice is consistent and based on rigorous scientific research.

Conclusions

Our findings underscore the importance of ensuring that patients treated with GLP-1 based therapies are closely monitored and provided with comprehensive nutrition and lifestyle support to ensure they achieve the best long-term health outcomes.
背景:肥胖是一种与过度肥胖相关的异质性全身性慢性疾病,病因复杂,在世界范围内的患病率正在上升。最初用于治疗2型糖尿病,以胰高血糖素样肽-1 (GLP-1)为基础的疗法现在广泛用于超重和肥胖患者,作为减少卡路里饮食和增加体育锻炼的辅助手段。然而,尽管GLP-1具有令人印象深刻的减肥能力,但许多接受GLP-1为基础的治疗的患者没有得到适当的营养建议,并且很难保持他们的减肥效果。方法本综述对现有文献进行了探讨和总结,探讨了肥胖患者采用基于GLP-1的治疗方法与营养摄入相关的挑战,以及对这些个体进行营养和生活方式干预的实际应用,以确保其最佳的长期健康结果。结果:为接受GLP-1治疗的肥胖患者提供最佳营养管理给医疗保健提供者带来了许多挑战,包括解决肥胖和体重减轻对身体成分的影响(特别是肌肉质量减少和肌肉减少性肥胖的风险),以及营养不良。医生应该与营养师和其他医疗保健提供者合作,提供以患者为中心的全面生活方式咨询,与个人的需求和偏好保持一致。这应包括以下方面的建议:及时和适当的营养,以充足的宏量营养素、微量营养素和液体摄入为中心,特别是增加蛋白质摄入量,同时进行阻力训练以保持肌肉质量;心理健康;睡眠卫生,身体活动;药物依从性和持久性。以证据为基础的营养指南还可以为卫生保健专业人员提供一个重要的框架,帮助确保营养建议的一致性,并以严格的科学研究为基础。结论:我们的研究结果强调了确保接受GLP-1治疗的患者受到密切监测并提供全面的营养和生活方式支持的重要性,以确保他们获得最佳的长期健康结果。
{"title":"Application of nutrition interventions with GLP-1 based therapies: A narrative review of the challenges and solutions","authors":"Angela Fitch ,&nbsp;Linda Gigliotti ,&nbsp;Harold Edward Bays","doi":"10.1016/j.obpill.2025.100205","DOIUrl":"10.1016/j.obpill.2025.100205","url":null,"abstract":"<div><h3>Background</h3><div>Obesity is a heterogeneous systemic chronic disease associated with excess adiposity and a complex etiology and is increasing in prevalence worldwide. Initially used to treat type 2 diabetes mellitus, glucagon-like peptide-1 (GLP-1) based therapies are now widely prescribed for individuals with overweight and obesity as an adjunct to a reduced-calorie diet and increased physical activity. However, despite their impressive weight reduction capabilities, many patients on GLP-1 based therapies do not receive appropriate nutrition advice and struggle to maintain their weight reduction.</div></div><div><h3>Methods</h3><div>This narrative review explores and summarizes existing literature on the challenges associated with nutrition intake in people with obesity taking GLP-1 based therapies and practical applications of nutrition and lifestyle interventions for the management of these individuals to ensure their best long-term health outcomes.</div></div><div><h3>Results</h3><div>Delivering optimal nutrition management to people with obesity treated with GLP-1 based therapies presents healthcare providers with many challenges including addressing the impact of obesity and weight reduction on body composition (particularly muscle mass loss and risk of sarcopenic obesity), and poor nutrition. Physicians should work with dietitians and other healthcare providers to deliver comprehensive lifestyle counselling that is patient-centered, aligning with the needs and preferences of the individual. This should include advice on: timely and appropriate nutrition that centers on adequate macronutrient, micronutrient and fluid intake, particularly increased protein intake alongside resistance training for the preservation of muscle mass; mental health; sleep hygiene, physical activity; and medication adherence and persistence. Evidence-based nutrition guidelines can also provide an important framework for healthcare professionals, helping to ensure nutrition advice is consistent and based on rigorous scientific research.</div></div><div><h3>Conclusions</h3><div>Our findings underscore the importance of ensuring that patients treated with GLP-1 based therapies are closely monitored and provided with comprehensive nutrition and lifestyle support to ensure they achieve the best long-term health outcomes.</div></div>","PeriodicalId":100977,"journal":{"name":"Obesity Pillars","volume":"16 ","pages":"Article 100205"},"PeriodicalIF":0.0,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145105016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developing and implementing an obesity medicine fellowship program: Experience at a U.S. academic medical center 发展和实施肥胖医学奖学金计划:在美国学术医疗中心的经验
Pub Date : 2025-08-27 DOI: 10.1016/j.obpill.2025.100204
Zoobia W. Chaudhry , Marci Laudenslager , Kimberly A. Gudzune , Selvi Rajagopal

Background

Obesity is a prevalent and complex chronic disease yet physicians’ training in obesity care is often inadequate. Fellowship training in obesity medicine is now available at multiple academic medical centers; however, there has been limited description and evaluation of these programs to date. Therefore, this article describes our curriculum development process and fellowship program implementation experience at a U.S. academic medical center.

Methods

This was a structured, multi-phase curriculum development study guided by established obesity medicine competencies and certification standards. We used a six-step approach to curriculum development to guide our design with content informed by the Obesity Medicine Education Collaborative competencies, American Board of Obesity Medicine (ABOM) content outline, and Accreditation Council for Graduate Medical Education - International Obesity Medicine Fellowship program requirements. We utilized several tools of instruction as well as modes of assessing learners. Feedback from fellows and faculty was used to iteratively refine the program over the initial 3 years.

Results

We identified 19 content domains key for obesity medicine. Within each domain, we created instructional components including didactic e-lectures, directed readings, reflective assignments, role play activities, and clinical experiences. We developed evaluation tools to determine trainee progress including knowledge check assessments, mini-clinical evaluation exercises (mini-CEXs), and structured feedback. Early outcomes indicate that trainees achieve competence in obesity care, engage in meaningful scholarly activity, and benefit from professional development opportunities. All graduating fellows have successfully achieved ABOM certification. Feedback has informed fellowship refinements, particularly improvements in rotation timing and duration as well as additional subspecialty elective options.

Conclusion

This obesity medicine fellowship curriculum provides a structured, multidisciplinary program and graduates have achieved competency in obesity care. Obesity medicine fellowship training holds promise in advancing the field through innovative education and leadership development.
背景:肥胖是一种普遍而复杂的慢性疾病,但医生在肥胖护理方面的培训往往不足。肥胖医学的奖学金培训现在在多个学术医疗中心提供;然而,迄今为止,对这些项目的描述和评估都很有限。因此,本文描述了我们在美国学术医疗中心的课程开发过程和奖学金项目的实施经验。方法本研究是一项结构化的、多阶段的课程开发研究,以既定的肥胖医学能力和认证标准为指导。我们采用六步法来指导课程设计,内容参考肥胖医学教育合作能力、美国肥胖医学委员会(ABOM)内容大纲和研究生医学教育认证委员会-国际肥胖医学奖学金项目要求。我们使用了几种教学工具以及评估学习者的模式。在最初的3年里,研究员和教师的反馈被用来迭代地完善这个项目。结果鉴定出19个肥胖医学关键内容域。在每个领域中,我们创建了教学组件,包括教学电子讲座、指导阅读、反思作业、角色扮演活动和临床经验。我们开发了评估工具来确定受训人员的进步,包括知识检查评估、迷你临床评估练习(mini- ces)和结构化反馈。早期结果表明,受训者在肥胖护理方面获得了能力,参与了有意义的学术活动,并从专业发展机会中受益。所有毕业生均成功取得ABOM认证。反馈已经告知奖学金的改进,特别是轮转时间和持续时间的改进,以及额外的亚专业选修选项。结论该肥胖医学奖学金课程提供了一个结构化的、多学科的课程,毕业生已具备肥胖护理的能力。肥胖医学奖学金培训有望通过创新教育和领导力发展推动该领域的发展。
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引用次数: 0
Healthcare professionals’ perspectives on the current state of obesity management training: A mix methods study 医疗保健专业人员对肥胖管理培训现状的看法:一项混合方法研究
Pub Date : 2025-08-19 DOI: 10.1016/j.obpill.2025.100202
Francisca Contreras, Tak Ying Louise Ko, Carel W. le Roux, Werd Al-Najim

Introduction

Obesity is a disease that represents a major global health problem, affecting over a quarter of European adults and straining healthcare systems. Despite its multifactorial causes, many healthcare professionals lack adequate training and confidence in delivering effective, person-centered obesity care. Weight stigma and misconceptions further impair outcomes. Thus, improved education and interprofessional training are essential to support healthcare professionals in delivering optimal obesity care. The aim of this study is to explore the current state of obesity management training among healthcare professionals working in obesity management services by identifying perceived training gaps, confidence levels and impact on clinical practice.

Methodology

This study employed a mixed-methods design by combining a cross-sectional survey of 100 healthcare professionals with semi-structured interviews of 20 professionals who work in obesity management. Survey data were analyzed descriptively, and interview transcripts underwent thematic analysis using Braun and Clarke's framework.

Results

Of the 100 healthcare professionals surveyed, 88 % reported actively working in obesity management and completed the full survey. Undergraduate training in obesity care was limited, with only 44 % receiving any, and only 12 % rated it as good or excellent. Postgraduate training was pursued by 51 %, with only 6 % completing formal advanced education. Participant perceptions of obesity training were organized in 5 domains: a) Current state of obesity management training, b) Confidence level, c) Gaps in training, d) Impact on clinical practice and d) Recommendation for obesity training curriculum.

Conclusion

Healthcare professionals report significant gaps in obesity management training that impact their confidence and clinical practice. The key recommendations made by participants in this study reflect both the perceived deficits and a clear demand for more structured and comprehensive training in obesity management. Integrating structured, evidence-based obesity education into healthcare training programs is essential to reduce stigma, build competence, and improve obesity care.
肥胖症是一种代表全球主要健康问题的疾病,影响着超过四分之一的欧洲成年人,并使医疗保健系统不堪重负。尽管其多因素的原因,许多医疗保健专业人员缺乏足够的培训和信心,提供有效的,以人为本的肥胖护理。体重歧视和误解进一步损害了结果。因此,改善教育和跨专业培训对于支持医疗保健专业人员提供最佳的肥胖护理至关重要。本研究的目的是通过识别培训差距、信心水平和对临床实践的影响,探讨肥胖管理服务卫生保健专业人员的肥胖管理培训现状。本研究采用混合方法设计,对100名医疗保健专业人员进行横断面调查,对20名肥胖管理专业人员进行半结构化访谈。采用Braun和Clarke的框架对调查数据进行描述性分析,并对访谈记录进行专题分析。结果在接受调查的100名医疗保健专业人员中,88%的人报告积极从事肥胖管理工作并完成了完整的调查。大学生在肥胖治疗方面的培训是有限的,只有44%的人接受过培训,只有12%的人认为培训是好的或优秀的。51%的人接受研究生培训,只有6%的人完成了正规的高等教育。参与者对肥胖培训的看法分为5个方面:a)肥胖管理培训的现状,b)信心水平,c)培训差距,d)对临床实践的影响,d)对肥胖培训课程的建议。结论医疗保健专业人员报告肥胖管理培训存在显著差距,影响了他们的信心和临床实践。本研究参与者提出的关键建议既反映了肥胖管理方面的缺陷,也反映了对更有组织、更全面的培训的明确需求。将结构化的、以证据为基础的肥胖教育纳入医疗保健培训计划,对于减少耻辱感、建立能力和改善肥胖护理至关重要。
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引用次数: 0
Impact of physical activity and BMI on health-related quality of life in overweight Indian adolescents: A randomized controlled study 身体活动和BMI对超重印度青少年健康相关生活质量的影响:一项随机对照研究
Pub Date : 2025-08-16 DOI: 10.1016/j.obpill.2025.100201
Prateek Srivastav , K. Vaishali , H. Vinod Bhat , Suzanne Broadbent

Background

Health-related quality of life (HRQOL) is a critical yet often overlooked component of adolescent obesity management. While physical activity (PA) and body mass index (BMI) are established markers of health, their combined influence on HRQOL in Indian adolescents remains underexplored.

Objective

To examine how PA and BMI influence overall and domain-specific HRQOL in overweight and adolescents with obesity following a structured lifestyle program.

Methods

In this randomized controlled study, 604 adolescents (aged 11–16 years) with BMI above the 85th percentile were recruited from schools in Udupi, India. Individuals were randomized into three groups: multifactorial strategy (MFI: exercise, lifestyle education, behavioral counseling), exercise-only (EX), and Control group (CON). PA was measured using the Physical Activity Questionnaire for Adolescents (PAQ-A), and HRQOL was measured via the Pediatric Quality of Life Inventory (PedsQL 4.0). Linear mixed-effects models evaluated associations between PA, BMI, and HRQOL over a 12-month period, which included a 12-week intervention followed by 9 months of follow-up.

Results

PA was linked with better HRQOL in the MFI (β = 9.30, p < 0.001) and EX (β = 4.47, p < 0.001) groups. Interestingly, higher BMI correlated with better HRQOL scores in both program arms. The CON group showed no meaningful association between PA and HRQOL. The domain-level analysis found that PA and BMI were positively linked to physical, emotional, social, and school functioning in both program groups, with more pronounced effects in the MFI group. The CON group showed improvement only in emotional functioning related to BMI.

Conclusion

Structured PA programs, especially those combining education and behavioral support, notably enhance the quality of life among overweight Indian adolescents. These findings reinforce the importance of focusing not solely on weight loss, but on holistic, behavior-driven health outcomes in adolescent obesity care.

Clinical trial registration

CTRI/2019/04/018,834.
背景:与健康相关的生活质量(HRQOL)是青少年肥胖管理中一个关键但经常被忽视的组成部分。虽然身体活动(PA)和身体质量指数(BMI)是公认的健康指标,但它们对印度青少年HRQOL的综合影响仍未得到充分探讨。目的探讨PA和BMI如何影响超重和青少年肥胖患者遵循结构化生活方式计划的整体和特定领域的HRQOL。方法在这项随机对照研究中,从印度Udupi的学校招募了体重指数高于85百分位的604名青少年(11-16岁)。个体被随机分为三组:多因素策略组(MFI:运动,生活方式教育,行为咨询),只运动组(EX)和对照组(CON)。使用青少年体育活动问卷(PAQ-A)测量PA,通过儿科生活质量量表(PedsQL 4.0)测量HRQOL。线性混合效应模型评估了12个月期间PA、BMI和HRQOL之间的关系,其中包括12周的干预和9个月的随访。结果在MFI组(β = 9.30, p < 0.001)和EX组(β = 4.47, p < 0.001)中,spa与较好的HRQOL相关。有趣的是,在两个项目组中,较高的BMI与较好的HRQOL评分相关。CON组PA与HRQOL之间无显著相关性。领域水平分析发现,在两个项目组中,PA和BMI与身体、情感、社会和学校功能呈正相关,在MFI组中效果更明显。CON组仅在与BMI相关的情绪功能上有所改善。结论结构化的PA项目,特别是那些将教育和行为支持相结合的项目,显著提高了印度超重青少年的生活质量。这些发现强调了在青少年肥胖护理中,不仅要关注减肥,还要关注整体的、行为驱动的健康结果的重要性。临床试验注册ctri /2019/04/018,834。
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引用次数: 0
Obesity Medicine Association statement regarding online pharmacologic management of obesity 肥胖医学协会关于肥胖在线药理学管理的声明
Pub Date : 2025-08-08 DOI: 10.1016/j.obpill.2025.100200
Leslie Golden, Harold Edward Bays
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引用次数: 0
Obesity treatment as a bridge to solid organ transplantation: A comparison of bariatric surgery to medical therapy 肥胖治疗作为实体器官移植的桥梁:减肥手术与药物治疗的比较
Pub Date : 2025-07-26 DOI: 10.1016/j.obpill.2025.100199
Kevin L. Roddy, Matthew R. Greenwald, Nicholas Hollman, Madisen F. Dorand, Jesse R. Richards

Background

Organ transplant is a rapidly growing area of medicine, with over 42,800 organ transplants occurring in 2022.[1] Obesity complicates the transplant surgery process; historically, the only available treatment for patients with both severe obesity and end-organ damage requiring transplant was bariatric surgery. Glucagon-like peptide-1 (GLP-1) and dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) agonists (such as semaglutide and tirzepatide, respectively) may offer a non-surgical alternative to weight management prior to transplant surgery.

Methods

This descriptive case series utilized retrospective chart review to compare peri-transplant weight loss in individuals treated with bariatric surgery alone, GLP-1 or GLP-1/GIP medication without surgical intervention, and GLP-1 or GLP-1/GIP medication with surgical intervention. Nineteen (N = 19) patients pursuing kidney transplant met inclusion criteria. Primary outcomes of interest in each group were median weight loss, total weight loss percent, and portion of individuals who met the BMI cut-off for transplantation following the intervention.

Results

Individuals treated with tirzepatide (n = 9) demonstrated 8 % less weight loss than the surgical-intervention group, and 77.8 % (n = 7) met BMI cutoff for transplant after treatment. Among patients treated with semaglutide (n = 4), 50 % (n = 2) met BMI cutoff for transplant. In the bariatric-surgery only group, 66.7 % (n = 2) met the BMI cutoff for transplant. Among those who received both bariatric surgery and GLP-1 medication (n = 3), all met the BMI cutoff for transplant.

Conclusions

This descriptive case series demonstrates that the current generation of weight loss medications produce a degree of weight loss comparable to bariatric surgery; this is particularly relevant to individuals with obesity who are pursuing organ transplant. Conclusions are limited due to the small, retrospective, and observational nature of this study; however, the results support the hypothesis that medications could revolutionize the organ transplant process by providing a reasonable non-surgical weight loss option for individuals with obesity. Further study with a larger, prospective randomized trial is needed to fully evaluate the viability of utilizing anti-obesity medications for this unique clinical indication.
器官移植是一个快速发展的医学领域,2022年将有超过42,800例器官移植肥胖使移植手术过程复杂化;从历史上看,对于严重肥胖和终末器官损伤需要移植的患者,唯一可用的治疗方法是减肥手术。胰高血糖素样肽-1 (GLP-1)和双GLP-1/葡萄糖依赖性胰岛素多肽(GIP)激动剂(如分别为西马鲁肽和替西肽)可以提供移植手术前体重管理的非手术替代方案。方法:本描述性病例系列采用回顾性图表回顾,比较单独接受减肥手术、不进行手术干预的GLP-1或GLP-1/GIP治疗和手术干预的GLP-1或GLP-1/GIP治疗的患者移植期体重减轻情况。19例(N = 19)肾移植患者符合纳入标准。各组的主要结局为干预后中位体重减轻、总体重减轻百分比和达到BMI分界点的移植个体比例。结果接受替西帕肽治疗的患者(n = 9)比手术干预组体重减轻8%,77.8%的患者(n = 7)在治疗后达到BMI临界值。在接受semaglutide治疗的患者中(n = 4), 50% (n = 2)达到了移植所需的BMI临界值。在仅进行减肥手术的组中,66.7% (n = 2)的患者达到了移植所需的BMI临界值。在同时接受减肥手术和GLP-1药物治疗的患者中(n = 3),所有人都达到了移植的BMI临界值。结论:该描述性病例系列表明,当前一代减肥药产生的减重程度与减肥手术相当;这对正在寻求器官移植的肥胖患者尤其重要。由于本研究规模小、回顾性和观察性,结论有限;然而,研究结果支持了一种假设,即药物可以通过为肥胖患者提供合理的非手术减肥选择,从而彻底改变器官移植过程。进一步的研究需要更大的前瞻性随机试验来充分评估使用抗肥胖药物治疗这一独特临床适应症的可行性。
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引用次数: 0
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Obesity Pillars
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