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Insucesso da Técnica Radial em Centro com Alto Volume de Procedimentos 失败的径向中心技术与大量的程序
Pub Date : 2014-12-01 DOI: 10.1590/0104-1843000000055
P. Andrade, Fábio Salerno Rinaldi, Igor Ribeiro de Castro Bienert, Robson Alves Barbosa, Marcos Henriques Bergonso, Milena Paiva Brasil de Matos, Maycon Soto Simplício, Ederlon Ferreira Nogueira, V. Esteves, Sérgio Kreimer, Marden André Tebet, L. A. Mattos, André Labrunie
Failure of the Transradial Approach in a High-Volume Center background: The mechanisms and predictors of failed transradial approach in centers dedicated to this technique are not well characterized and were the main objective of this analysis. methods: 6,808 consecutive patients undergoing transradial coronary procedures by operators with utilization rate greater than 90% were included. Simple and multiple logistic regression models were used to identify the predictors of failed transradial approach. Results: Transradial failure rate was 1.7%. Vascular complications were observed in 5%, with a prevalence of asymptomatic arterial occlusion and subcutaneous hematomas. Predictors of failure were female gender (OR = 1.87; 95% CI 1.29-2.71; p = 0.01), age > 70 years (OR = 1.78; 95% CI 1.06-2.98; p = 0.03) and presence of chronic peripheral arterial disease (OR = 5.71; 95% CI 2.40-13.54; p < 0.01). Conclusions: In a high-volume radial center, failure rate was < 2% and variables associated with technical failure were female gender, advanced age and peripheral arterial disease. DesCRIPToRs: Radial artery. Percutaneous coronary intervention. Hemorrhage. Ischemia.
在大容量中心背景下,经桡骨入路的失败:在专门采用该技术的中心,经桡骨入路失败的机制和预测因素尚未得到很好的表征,这是本分析的主要目的。方法:连续6808例经桡动脉冠状动脉手术患者,手术使用率大于90%。使用简单和多元逻辑回归模型来确定失败的预测因素。结果:经桡动脉失败率为1.7%。血管并发症发生率为5%,伴有无症状动脉闭塞和皮下血肿。失败的预测因素为女性(OR = 1.87;95% ci 1.29-2.71;p = 0.01),年龄> 70岁(OR = 1.78;95% ci 1.06-2.98;p = 0.03)和存在慢性外周动脉疾病(OR = 5.71;95% ci 2.40-13.54;P < 0.01)。结论:在大容量放射状中心,失败率< 2%,与技术失败相关的变量为女性、高龄和外周动脉疾病。描述:桡动脉。经皮冠状动脉介入治疗。出血。缺血。
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引用次数: 3
Resultados Clínicos Tardios do Stent Farmacológico Liberador de Sirolimus Firebird® no Tratamento de Pacientes com Doença Arterial Coronária na Prática Diária – Seguimento de 24 Meses do Registro CLARIFIRE 西罗莫司火鸟®药物释放支架在日常实践中治疗冠状动脉疾病患者的晚期临床结果- CLARIFIRE记录的24个月随访
Pub Date : 2014-12-01 DOI: 10.1590/0104-1843000000054
R. Souza, R. Costa, Alexandre Abizaid, Mônica Buchalla, R. R. L. Bueno, George César Ximenes Meireles, K. Martins, J. R. M. Filho, C. O. Costantini, Décio Salvadori, Wilson A. Pimentel-Filho, Andrea C. Abizaid, Juliana P. Castro, E. Ribeiro, Fausto Feres
Background: The Firebird™ sirolimus-eluting stent has proven to be effective in inhibiting neointimal hyperplasia in selected patients undergoing percutaneous coronary intervention. Our objective was to evaluate the performance and long-term outcomes of Firebird ™ in patients undergoing percutaneous coronary intervention in daily practice in Brazil. Methods: The CLARIFIRE Registry was a prospective, non-randomized, multicenter study enrolling 455 patients (536 lesions) in 14 Brazilian sites between December 2008 and May 2011. Clinical follow-up was performed at 1, 6, 12, and 24 months, and adverse events were adjudicated by the independent Clinical Events Committee. Results: Mean age was 61.1 ± 10.4 years, 30.8% were women, 41.9% had diabetes, and 58.2% had stable angina. The left anterior descending artery was the most prevalent target vessel (46.5%), 29.9% were restenotic lesions, and 8% were bifurcations. Six hundred and thirteen stents were implanted, and the mean nominal stent length and diameter were 22.0 ± 6.4 mm and 2.90 ± 0.40 mm, respectively. Procedural success was 97.6%. The cumulative major adverse cardiac events rate at 12 months (primary endpoint) was 8.1%. Considering post-discharge events up to 24 months (409/455), major adverse cardiac events were observed in 9.8%, cardiac death in 3.9%, and target vessel revascularization in 7.6% of the patients. Definite/probable stent thrombosis was observed in nine cases (2%) up to 30 days, and no further occurrences were found. Conclusions: The Firebird ™ sirolimus-eluting stent has demonstrated good performance and sustained safety and efficacy for patients treated in daily practice, as evidenced by the high procedural success rates and relatively low adverse event rates after 2 years.
背景:Firebird™西罗莫司洗脱支架已被证明对经皮冠状动脉介入治疗的患者有效抑制内膜增生。我们的目的是评估Firebird™在巴西日常经皮冠状动脉介入治疗患者中的表现和长期疗效。方法:CLARIFIRE注册是一项前瞻性、非随机、多中心研究,在2008年12月至2011年5月期间,在巴西的14个地点招募了455名患者(536个病灶)。在1、6、12和24个月进行临床随访,不良事件由独立的临床事件委员会裁决。结果:平均年龄61.1±10.4岁,女性占30.8%,糖尿病占41.9%,稳定型心绞痛占58.2%。左前降支是最常见的靶血管(46.5%),再狭窄占29.9%,分叉占8%。共植入支架613个,支架标称长度和直径分别为22.0±6.4 mm和2.90±0.40 mm。手术成功率为97.6%。12个月(主要终点)累计主要心脏不良事件发生率为8.1%。考虑到出院后24个月的事件(409/455),主要心脏不良事件发生率为9.8%,心脏性死亡发生率为3.9%,靶血管重建术发生率为7.6%。9例(2%)在30天内观察到明确/可能的支架血栓形成,未发现进一步发生。结论:Firebird™西罗莫司洗脱支架在患者的日常治疗中表现出良好的性能和持续的安全性和有效性,2年后手术成功率高,不良事件发生率相对较低。
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引用次数: 0
Tratamento Endovascular de Aneurisma de Aorta Abdominal pela Técnica de Chaminé 烟囱技术治疗腹主动脉瘤的血管内治疗
Pub Date : 2014-12-01 DOI: 10.1590/0104-1843000000065
Adriano Gonçalves de Araújo, F. H. Souza, Fernando Henrique Fernandes, Flávio Passos Barbosa, José Antônio Jatene, Paulo Cézar Guimarães Câmara
An elderly patient with non-dialysis renal failure and oxygendependent chronic obstructive pulmonary disease was admitted to the emergency room with lancinating abdominal pain. Angiotomography of the abdomen revealed the presence of a large aortic aneurysm with involvement of visceral arteries. Due to the high surgical risk, endovascular repair was proposed, using the chimney graft technique for the preservation of the visceral vessels. This technique is promising because it enables endovascular repair of aneurysms, be it in elective cases, emergencies, or rescue of a visceral artery accidentally covered by an aortic stent graft.
一例老年非透析性肾功能衰竭伴氧依赖型慢性阻塞性肺疾病患者因腹胀性腹痛被送入急诊室。腹部血管断层扫描显示一巨大的主动脉瘤并累及内脏动脉。由于手术风险高,血管内修复被提出,使用烟囱移植技术来保存内脏血管。这项技术很有前景,因为它可以在选择性病例、紧急情况或抢救意外被主动脉支架覆盖的内脏动脉时进行血管内动脉瘤修复。
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引用次数: 2
Comparação entre os Tempos de Procedimento e Fluoroscopia e o Volume de Contraste das Vias de Acesso Radial e Femoral em Pacientes Submetidos a Cateterismo Cardíaco 心导管插入术患者的手术和透视时间及桡骨和股骨通路对比量的比较
Pub Date : 2014-12-01 DOI: 10.1590/0104-1843000000058
T. Vargas, Barbara Cardoso Campos, Naury de Jesus Danzi Soares, Luciano Magalhães Vitorino, S. Ibrahim, Bruno Laurenti Janella
Background: There is controversy in the literature about the advantages of the radial vs. femoral access route for diagnostic catheterizations. This study aimed to compare the radial and femoral access for procedural and fluoroscopy times and for contrast volume. Methods: This was an observational, retrospective study based on the records of consecutive patients undergoing cardiac catheterization from July 2012 to December 2013. Results: We evaluated 192 patients and the radial access was used in 78.1% of the cases. Mean age was 63.1 ± 11.9 years, most were male (55.7%) and 21.4% had diabetes. Procedural time was lower in the radial group: 12.0 minutes (9.0 to 17.2 minutes) vs. 18.3 minutes (12.0 to 34.5 minutes), p < 0.01. Fluoroscopy time was 270.0 seconds (180.0 to 389.5 seconds) vs. 244.0 seconds (175.3 to 705.0 seconds), and there was no difference between groups (p = 0.59). Contrast volume was lower in the radial group: 100.0 mL (75.0 to 117.5 mL) vs. 100.0 mL (80.0 to 150.0 mL), p < 0.01. Conclusions: In this laboratory, which favored the radial access for cardiac catheterization, procedural and fluoroscopy times, as well as contrast volume, were lower or comparable to the femoral access.
背景:关于桡骨与股动脉导管入路在诊断性置管中的优势,文献中存在争议。本研究旨在比较桡骨入路和股骨入路的手术时间和透视时间以及造影剂体积。方法:基于2012年7月至2013年12月连续心导管置入术患者的观察性、回顾性研究。结果:我们对192例患者进行了评估,78.1%的患者采用了桡骨通路。平均年龄63.1±11.9岁,男性居多(55.7%),糖尿病患者占21.4%。桡骨组手术时间较短:12.0分钟(9.0 ~ 17.2分钟)vs. 18.3分钟(12.0 ~ 34.5分钟),p < 0.01。透视时间分别为270.0秒(180.0 ~ 389.5秒)和244.0秒(175.3 ~ 705.0秒),组间差异无统计学意义(p = 0.59)。桡动脉组造影剂体积较低:100.0 mL (75.0 ~ 117.5 mL)比100.0 mL (80.0 ~ 150.0 mL), p < 0.01。结论:在本实验室,桡动脉入路更适合心导管插管,手术和透视时间,以及造影剂体积,比股骨入路更低或相当。
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引用次数: 1
Intervenção Coronária Percutânea em Pacientes Jovens 年轻患者经皮冠状动脉介入治疗
Pub Date : 2014-12-01 DOI: 10.1590/0104-1843000000059
M. J. C. Cantarelli, H. Castello, Rosaly Gonçalves, Silvio Gioppato, Ednelson Cunha Navarro, J. B. Guimarães, E. Ribeiro, Danilo Maksud, Julio Cesar Francisco Vardi
Background: Cardiovascular disease has shown increasing occurrence rates among young people and data of percutaneous coronary intervention (PCI) in this group are scarce. Our objective was to perform a retrospective evaluation of the profile and in-hospital clinical outcomes of young patients in this PCI registry. Methods: From 2006 to 2012, 6,288 patients were consecutively submitted to PCI, of whom 151 were 0.99), myocardial infarction (3.3% vs. 2.3%; p = 0.41) or emergency revascularization (0.6% vs. 0.03%; p = 0.56) were similar between groups. In the multivariate analysis, age and presence of functional class Killip III and IV were the variables that best explained the occurrence of MACCE. Conclusions: Patients with age < 40 years represented a small fraction of the cases in this series and had a clinical and angiographic profile different from the older patients, suggesting the need to establish primary prevention measures earlier in individuals with the observed profile.
背景:心血管疾病在年轻人中的发病率越来越高,而经皮冠状动脉介入治疗(PCI)在这一群体中的数据很少。我们的目的是对该PCI登记的年轻患者的概况和住院临床结果进行回顾性评估。方法:2006 - 2012年,6288例患者连续行PCI,其中151例(0.99),心肌梗死(3.3% vs. 2.3%;P = 0.41)或紧急血运重建术(0.6% vs. 0.03%;P = 0.56)组间相似。在多变量分析中,年龄和功能等级Killip III和IV的存在是最能解释MACCE发生的变量。结论:年龄< 40岁的患者只占本系列病例的一小部分,其临床和血管造影特征与老年患者不同,这表明有必要在观察到的个体中早期建立一级预防措施。
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引用次数: 6
Oclusão Percutânea da Persistência do Ducto Arterioso 经皮闭塞持续动脉导管
Pub Date : 2014-12-01 DOI: 10.1590/0104-1843000000061
Julian Rathke, H. S. Menezes, Raul Ivo Rossi-Filho, J. L. Manica
Background: Patent ductus arteriosus is a congenital condition with high morbidity, especially in preterm infants of extremely low birth weight, representing 5% to 10% of congenital heart diseases. Our objective was to describe the approaches used at a reference hospital for the percutaneous occlusion of PDA. Methods: We conducted a retrospective study on the transcatheter treatment of patent ductus arteriosus from April of 2008 to April of 2010. Results: Forty-seven cases were reviewed and most of them (78.8%) were treated with FlipperTM coils while the remaining patients received the AmplatzerTM device. Ductal morphological configuration was Krichenko type A in 89.4% (34 in the FlipperTM coil group and 8 in the AmplatzerTM group), type D in 6.4% (2 in the FlipperTM coil group and 1 in the AmplatzerTM group) and type E in 4.2% (1 in each group) of patients. Pre-catheterization minimum diameters were 2.6 ± 0.8 mm and 3.8 ± 1.6 mm for the FlipperTM coil and AmplatzerTM groups, respectively. Immediate total occlusion of the defect was obtained in the control angiography in 72.3% of the patients. Seven patients treated with the FlipperTM coil received additional coils and two patients treated with the AmplatzerTM device presented minimal residual shunts. There were no procedure-related complications. In the follow-up after hospital discharge, one patient presented minimal residual shunt at the echography, 45 days after catheterization. Conclusions: Percutaneous patent ductus arteriosus occlusion has proven to be safe and effective in most cases.
背景:动脉导管未闭是一种高发病率的先天性疾病,特别是在极低出生体重的早产儿中,占先天性心脏病的5% ~ 10%。我们的目的是描述在一家参考医院用于经皮PDA闭塞的入路。方法:回顾性分析2008年4月至2010年4月经导管治疗动脉导管未闭的病例。结果:47例患者采用FlipperTM线圈治疗,78.8%的患者采用AmplatzerTM装置治疗。导管形态形态为Krichenko A型占89.4% (FlipperTM线圈组34例,AmplatzerTM组8例),D型占6.4% (FlipperTM线圈组2例,AmplatzerTM组1例),E型占4.2%(每组1例)。FlipperTM线圈组和AmplatzerTM组插管前最小直径分别为2.6±0.8 mm和3.8±1.6 mm。在对照血管造影中,72.3%的患者获得缺损立即完全闭塞。7名使用FlipperTM线圈治疗的患者接受了额外的线圈治疗,2名使用AmplatzerTM装置治疗的患者出现了最小残留分流。无手术相关并发症。在出院后的随访中,1例患者在置管后45天的超声检查中出现最小残留分流。结论:经皮动脉导管未闭闭塞术在大多数情况下是安全有效的。
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引用次数: 1
Oclusão Percutânea do Apêndice Atrial Esquerdo e do Forame Oval Patente no Mesmo Procedimento sem Necessidade de Punção Transeptal 经皮闭塞左房附件和椭圆形孔,无需经隔穿刺
Pub Date : 2014-12-01 DOI: 10.1590/0104-1843000000064
F. Chamié, Daniel Chamié, L. C. Simões, Ê. Guérios, João Carlos Tress
Left atrial appendage occlusion has been successfully employed to prevent embolic events in patients with atrial fibrillation as an alternative to oral anticoagulation. Left atrial access through the patent foramen ovale or ostium secundum atrial septal defect has been discouraged due to the fear that entering the septum in a higher position through the foramen would prevent adequate device positioning. In this manuscript we report a case in which the left atrial appendage and the foramen ovale were sequentially occluded avoiding transseptal puncture, making the procedure simpler and faster.
左心房附件闭塞已成功地用于预防栓塞事件的心房颤动患者作为替代口服抗凝。由于担心通过卵圆孔未闭或房间隔第二孔缺损进入左房通道会妨碍适当的装置定位,因此不鼓励使用左房通道。在这篇手稿中,我们报告了一例左心房附件和卵圆孔连续闭塞,避免了经间隔穿刺,使手术更简单,更快。
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引用次数: 2
Comparação do Tempo de Fluoroscopia Durante Cateterismo Cardíaco pelas Vias Radial e Femoral 桡动脉和股动脉导管透视时间比较
Pub Date : 2014-12-01 DOI: 10.1590/0104-1843000000057
R. R. Barbosa, F. Cesar, Renato Giestas Serpa, Vinícius Fraga Mauro, J. Edson Ferreira Jr., Denis Moulin dos Reis Bayerl, Walkimar Ururay Gloria Veloso, R. Cesar, Pedro Abílio Ribeiro Reseck
Background: The use of radial access in cardiac interventions is associated with reduced vascular complications, however it demands a longer learning curve and may increase fluoroscopy time. This study aimed to evaluate the fluoroscopy time as a surrogate marker of radiation exposure, during diagnostic cardiac catheterization by radial and femoral routes. Methods: Retrospective observational study including patients who underwent cardiac catheterization from July 2013 to October 2014. Radial and femoral groups were compared for total procedural time, fluoroscopy time, fluoroscopy to procedural time ratio and vascular complications. Results: The study included 1,915 procedures, 11.2% of which performed by radial approach and 88.8%, by femoral approach. A male prevalence was found in the radial group (80% vs. 54.1%, p < 0.01), but age (61.6 ± 9.7 years vs. 62.4 ± 11.6 years, p = 0.13), total procedural time (8.7 ± 3.8 vs. 8.1 ± 4.1 minutes, p = 0.91), fluoroscopy time (4.8 ± 2.7 vs. 4.1 ± 2.6 minutes, p = 0.89), fluoroscopy/procedure time ratio (0.56 ± 0.24 vs. 0.49 ± 0.32, p = 0.89), and major complications (0.0% vs. 0.3%, p = 0.55) were similar between groups. Conclusions: The use of the transradial approach for diagnostic procedures by experienced operating physicians may be used with an acceptable total procedural time without increasing the radiation exposure of the patient and staff, and with a low incidence of complications.
背景:在心脏介入手术中使用径向通路可减少血管并发症,但它需要较长的学习曲线,并可能增加透视时间。本研究旨在评估透视时间作为放射暴露的替代标记物,在桡骨和股动脉心导管诊断过程中。方法:回顾性观察研究纳入2013年7月至2014年10月行心导管置入术的患者。比较桡骨组和股骨组手术总时间、透视时间、透视时间与手术时间之比及血管并发症。结果:该研究包括1,915例手术,其中11.2%采用桡骨入路,88.8%采用股骨入路。男性患病率发现径向组(80%比54.1%,p < 0.01),但年龄(61.6±9.7年和62.4±11.6年,p = 0.13),总程序时间(8.7±3.8和8.1±4.1分钟,p = 0.91),透视时间(4.8±2.7和4.1±2.6分钟,p = 0.89),透视/过程时间比率(0.56±0.24和0.49±0.32,p = 0.89),和主要并发症(0.0%比0.3%,p = 0.55)类似的团体之间。结论:由经验丰富的手术医师使用经桡骨入路进行诊断手术,总手术时间可接受,不增加患者和工作人员的辐射暴露,并发症发生率低。
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引用次数: 2
Padrão de exposição radiológica em profissionais da saúde durante procedimentos cardiológicos invasivos 心脏病侵入性手术中卫生专业人员的辐射暴露模式
Pub Date : 2014-12-01 DOI: 10.1590/0104-1843000000053
Cristiano de Oliveira Cardoso, Cláudio Vasques de Moraes, J. V. D. S. Teixeira, L. S. Fischer, Gabriel Garcia Broetto, Bruna dos Santos Silva, Rogério Fachel de Medeiros, Rogério Sarmento-Leite, C. A. Gottschall
Introducao: Procedimentos cardiologicos invasivos expoem Medicos e enfermeiros/tecnicos de enfermagem aos riscos da radiacao ionizante. O objetivo deste estudo foi determinar os padroes de exposicao radiologica em profissionais da saude durante procedimentos cardiologicos. Metodos: Estudo prospectivo incluindo pacientes submetidos a procedimento cardiologico invasivo entre dezembro de 2011 e agosto de 2012 em equipamento com detectores do tipo plano. Caracteristicas clinicas, angiograficas e de exposicao a radiacao foram registradas em banco de dados especifico. Os padroes de exposicao a radiacao foram determinados em pacientes submetidos ao cateterismo cardiaco diagnostico. Correlacao entre dose do medico operador e enfermeiro/tecnico de enfermagem tambem foi efetuada. Resultados: Amostra incluiu 119 pacientes submetidos ao cateterismo. A dose de kerma no ar e o produto dose-area medio de radiacao recebida pelos pacientes foram de 549 ± 220 mGy e 29.054 ± 14.696 mGy.cm2, respectivamente. Medicos e enfermeiros/tecnicos de enfermagem foram expostos a dose efetiva media por exame de 0,47 ± 0,16 e 0,28 ± 0,13 mSv, respectivamente. A correlacao entre dose efetiva dos Medicos e enfermeiro/tecnicos de enfermagem foi de 0,54 ( p < 0,001). Conclusoes: Medicos e enfermeiros/tecnicos de enfermagem sao expostos a doses pequenas de radiacao ionizante durante cateterismo cardiaco diagnostico. Enfermeiros/tecnicos de enfermagem sao expostos a cerca de 60% da dose do medico operador.
简介:侵入性心脏病手术使医生和护士/护理技术人员暴露在电离辐射的风险中。本研究的目的是确定卫生专业人员在心脏病手术过程中的放射暴露模式。方法:这是一项前瞻性研究,包括2011年12月至2012年8月在平面检测器设备上接受有创心脏手术的患者。临床特征、血管造影和辐射暴露记录在特定的数据库中。在接受诊断性心导管插入术的患者中确定辐射暴露模式。此外,还对医生和护士/护理技术人员的剂量进行了相关性分析。结果:119例导尿管置入患者。患者接受的空气可玛剂量和平均辐射剂量-面积乘积分别为549±220 mGy和29.054±14.696 mGy。二,分别。医生和护士/护理技术人员的平均有效剂量分别为0.47±0.16和0.28±0.13 mSv。医生与护士/护理技术人员有效剂量的相关性为0.54 (p < 0.001)。结论:医生和护士/护理技术人员在诊断性心导管插入术中暴露于小剂量电离辐射。护士/护理技术人员接触的剂量约为医务人员剂量的60%。
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引用次数: 2
Índice Tornozelo-Braquial como Preditor de Doença Coronariana Significativa em Pacientes Submetidos à Angiografia Coronária 踝肱指数作为冠状动脉造影患者显著冠状动脉疾病的预测指标
Pub Date : 2014-12-01 DOI: 10.1590/0104-1843000000060
Marcelo Sabedotti, Rogério Sarmento-Leite, A. Quadros
Background: The ankle-brachial index is a simple and effective tool for diagnosing peripheral artery disease, but has not been validated for the diagnosis of coronary artery disease. The aim of this study was to evaluate the ability of the ankle-brachial index to predict coronary artery disease in patients undergoing coronary angiography. Methods: Patients with clinical suspicion of coronary artery disease and indication for coronary angiography were prospectively evaluated. Significant coronary artery disease was defined as the presence of stenosis > 70% of at least one major epicardial coronary artery or any of their major branches. A ROC curve was developed to define the ankle-brachial index cutoff that best predicts coronary artery disease. Results: A total of 312 patients were evaluated: mean age was 57 ± 11 years and 50% were male. One hundred and sixteen (37.2%) patients had significant coronary disease. Ankle-brachial index measurement in these patients was significantly lower than in those without coronary artery disease (0.88 ± 0.14 vs. 0.96 ± 0.87; p < 0.01). Ankle-brachial index < 0.87 showed a sensitivity of 31%, specificity of 95.4%, positive predictive value of 75.9% and negative predictive value of 71.6%. The area under the ROC curve was 0.73 (95% confidence interval of 0.67-0.79). Conclusions: Ankle-brachial index < 0.87 had a high specificity to predict significant coronary disease. Considering its low cost and ease of use, measurement of ankle-brachial index may be incorporated to daily clinical practice to help diagnose significant coronary artery disease.
背景:踝肱指数是诊断外周动脉疾病的一种简单有效的工具,但尚未被证实用于诊断冠状动脉疾病。本研究的目的是评估踝肱指数预测冠状动脉造影患者冠状动脉疾病的能力。方法:对临床怀疑有冠心病的患者及冠状动脉造影指征进行前瞻性评价。明显的冠状动脉疾病定义为至少有一条主要的心外膜冠状动脉或其任何主要分支狭窄> 70%。建立ROC曲线来定义最能预测冠状动脉疾病的踝-肱指数截止点。结果:共评估312例患者,平均年龄57±11岁,男性占50%。116例(37.2%)患者有明显冠心病。这些患者的踝肱指数测量明显低于无冠状动脉疾病的患者(0.88±0.14∶0.96±0.87;P < 0.01)。踝肱指数< 0.87,敏感性31%,特异性95.4%,阳性预测值75.9%,阴性预测值71.6%。ROC曲线下面积为0.73(95%可信区间为0.67 ~ 0.79)。结论:踝肱指数< 0.87对预测冠心病有较高的特异性。考虑到其低成本和易于使用,踝肱指数的测量可纳入日常临床实践,以帮助诊断重大冠状动脉疾病。
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引用次数: 7
期刊
Revista Brasileira de Cardiologia Invasiva
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