Revista Portuguesa de Pneumologia (English Edition)最新文献

英文中文

The role of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of lymphoproliferative disorders 超声引导下经支气管穿刺在淋巴细胞增生性疾病诊断中的作用

Revista Portuguesa de Pneumologia (English Edition)

Pub Date : 2017-11-01 DOI: 10.1016/j.rppnen.2017.07.007

V. Santos , A. Magalhães , M. Sucena , G. Fernandes

引用次数: 0

The reliability of short-term measurement of heart rate variability during spontaneous breathing in people with chronic obstructive pulmonary disease 慢性阻塞性肺疾病患者自主呼吸时心率变异性短期测量的可靠性

Revista Portuguesa de Pneumologia (English Edition)

Pub Date : 2017-11-01 DOI: 10.1016/j.rppnen.2017.06.001

C.A. Sima , J.A. Inskip , A.W. Sheel , S.F. van Eeden , W.D. Reid , P.G. Camp

Background

Reduced heart rate variability (HRV), a marker of autonomic system dysfunction, has been reported in patients with chronic obstructive pulmonary disease (COPD). Yet, limited data exists on the reliability of HRV measurement in this population. Here we investigated the reliability of short-term HRV measurement performed during spontaneous breathing in patients with COPD.

Methods

Thirteen individuals (8 males) with moderate-to-severe COPD (FEV₁ 46 ± 16% predicted; FEV₁/FVC 49 ± 13) underwent standard time and frequency domain HRV measurements derived from 5-minute electrocardiograms collected on two separate days using a SphygmoCor device. Absolute and relative reliability was assessed by a number of coefficients including within-subject random variation, systematic change in the mean, and retest correlations.

Results

Within-subject coefficients of variation (CV) ranged from 4.3% to 193.4%. The intraclass correlation coefficients (ICCs) ranged from 0.72 to 0.93 for parameters related to overall HRV, and from 0.57 to 0.59 for those related to parasympathetic tone in both time and frequency domains. Mean heart rate was the only parameter that showed excellent absolute and relative reliability (CV = 4.3%, ICC = 0.93).

Conclusion

The HRV measurements showed overall moderate-to-substantial reliability during spontaneous breathing in COPD population. Our findings support the use of HRV parameters for diagnosis and cardiac risk assessment, but only mean heart rate can be used reliably for monitoring changes in autonomic status following rehabilitation intervention in this population.

研究背景:慢性阻塞性肺疾病(COPD)患者心率变异性降低(HRV)是自主神经系统功能障碍的标志。然而，在这一人群中HRV测量的可靠性数据有限。在这里，我们研究了慢性阻塞性肺病患者在自主呼吸期间进行的短期HRV测量的可靠性。方法中重度COPD患者13例(男性8例)(预测FEV1 46±16%;FEV1/FVC(49±13)采用sphygmoor装置分别采集两天的5分钟心电图进行标准时间和频域HRV测量。绝对信度和相对信度通过一系列系数进行评估，包括受试者内随机变异、平均值的系统变化和重测相关性。结果受试者内变异系数(CV)范围为4.3% ~ 193.4%。类内相关系数(ICCs)在时间和频率域的范围为0.72 ~ 0.93，与总HRV相关的参数为0.57 ~ 0.59。平均心率是唯一表现出极好的绝对和相对可靠性的参数(CV = 4.3%， ICC = 0.93)。结论:在慢性阻塞性肺病患者的自主呼吸过程中，HRV测量总体上显示出中等到高度的可靠性。我们的研究结果支持使用HRV参数进行诊断和心脏风险评估，但只有平均心率可以可靠地用于监测该人群康复干预后自主神经状态的变化。

{"title":"The reliability of short-term measurement of heart rate variability during spontaneous breathing in people with chronic obstructive pulmonary disease","authors":"C.A. Sima , J.A. Inskip , A.W. Sheel , S.F. van Eeden , W.D. Reid , P.G. Camp","doi":"10.1016/j.rppnen.2017.06.001","DOIUrl":"10.1016/j.rppnen.2017.06.001","url":null,"abstract":"<div><h3>Background</h3><p>Reduced heart rate variability (HRV), a marker of autonomic system dysfunction, has been reported in patients with chronic obstructive pulmonary disease (COPD). Yet, limited data exists on the reliability of HRV measurement in this population. Here we investigated the reliability of short-term HRV measurement performed during spontaneous breathing in patients with COPD.</p></div><div><h3>Methods</h3><p>Thirteen individuals (8 males) with moderate-to-severe COPD (FEV<sub>1</sub> 46±16% predicted; FEV<sub>1</sub>/FVC 49±13) underwent standard time and frequency domain HRV measurements derived from 5-minute electrocardiograms collected on two separate days using a SphygmoCor device. Absolute and relative reliability was assessed by a number of coefficients including within-subject random variation, systematic change in the mean, and retest correlations.</p></div><div><h3>Results</h3><p>Within-subject coefficients of variation (CV) ranged from 4.3% to 193.4%. The intraclass correlation coefficients (ICCs) ranged from 0.72 to 0.93 for parameters related to overall HRV, and from 0.57 to 0.59 for those related to parasympathetic tone in both time and frequency domains. Mean heart rate was the only parameter that showed excellent absolute and relative reliability (CV=4.3%, ICC=0.93).</p></div><div><h3>Conclusion</h3><p>The HRV measurements showed overall moderate-to-substantial reliability during spontaneous breathing in COPD population. Our findings support the use of HRV parameters for diagnosis and cardiac risk assessment, but only mean heart rate can be used reliably for monitoring changes in autonomic status following rehabilitation intervention in this population.</p></div>","PeriodicalId":101122,"journal":{"name":"Revista Portuguesa de Pneumologia (English Edition)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rppnen.2017.06.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35152808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Tuberculosis in children from diagnosis to decision to treat 儿童结核病从诊断到决定治疗

Revista Portuguesa de Pneumologia (English Edition)

Pub Date : 2017-11-01 DOI: 10.1016/j.rppnen.2017.06.004

S. Ramos , R. Gaio , F. Ferreira , J. Paulo Leal , S. Martins , J. Vasco Santos , I. Carvalho , R. Duarte

Setting

Confirmation of tuberculosis (TB) in children is difficult, so clinicians use different procedures when deciding to treat.

Objective

Identify criteria to initiate and maintain TB treatment in children younger than 5 years-old, without diagnosis confirmation.

Design

A web-based survey was distributed by email to the corresponding authors of journal articles on childhood TB. The observations were clustered into disjoint groups, and analyzed by Ward's method.

Results

We sent out 260 questionnaires and received 64 (24.6%) responses. Forty-six respondents (71.9%) said that microbiological confirmation was not important for initiation of anti-TB treatment, and that the epidemiological context and signs/symptoms suggestive of disease were most important. Sixty-one respondents (95.3%) said that the decision to continue therapy was mainly dependent on clinical improvement. A cluster of older respondents (median age: 52 years-old) who were active at a hospital or primary health care centre placed the most value on immunological test results and chest X-rays. A cluster of younger respondents (median age: 38 years-old) who were less experienced in management of TB placed more value on Interferon Gamma Release Assay (IGRA) results and chest computed tomography (CT) scans. A cluster of respondents with more experience in treating TB and working at specialized TB centres placed greater value on the clinical results and specific radiological alterations (“tree-in-bud” pattern and pleural effusion).

Conclusion

TB management varied according to the age, work location and experience of the clinicians. It is necessary to establish standardized guidelines used for the diagnosis and decision to treat TB in children.

儿童结核病的确诊是困难的，因此临床医生在决定治疗时使用不同的程序。目的确定在没有确诊的5岁以下儿童中开始和维持结核病治疗的标准。DesignA基于网络的调查通过电子邮件分发给儿童结核病期刊文章的通讯作者。观察结果被聚类成不相交的组，并用沃德的方法进行分析。结果共发放问卷260份，回收回复率为24.6%。46个答复者(71.9%)表示，微生物鉴定对于开始抗结核治疗并不重要，流行病学背景和提示疾病的体征/症状最为重要。61名受访者(95.3%)表示继续治疗的决定主要取决于临床改善。在医院或初级保健中心工作的一组年龄较大的应答者(年龄中位数:52岁)最看重免疫检查结果和胸部x光片。一组年轻的应答者(中位年龄:38岁)在结核病管理方面经验不足，他们更看重干扰素γ释放试验(IGRA)结果和胸部计算机断层扫描(CT)。一组在治疗结核病和在专门的结核病中心工作方面经验更丰富的应答者更重视临床结果和特定的放射改变(“树芽”型和胸膜积液)。结论临床医生的年龄、工作地点和经验不同，结核病的管理也不同。有必要制定用于诊断和决定治疗儿童结核病的标准化指南。

{"title":"Tuberculosis in children from diagnosis to decision to treat","authors":"S. Ramos , R. Gaio , F. Ferreira , J. Paulo Leal , S. Martins , J. Vasco Santos , I. Carvalho , R. Duarte","doi":"10.1016/j.rppnen.2017.06.004","DOIUrl":"10.1016/j.rppnen.2017.06.004","url":null,"abstract":"<div><h3>Setting</h3><p>Confirmation of tuberculosis (TB) in children is difficult, so clinicians use different procedures when deciding to treat.</p></div><div><h3>Objective</h3><p>Identify criteria to initiate and maintain TB treatment in children younger than 5 years-old, without diagnosis confirmation.</p></div><div><h3>Design</h3><p>A web-based survey was distributed by email to the corresponding authors of journal articles on childhood TB. The observations were clustered into disjoint groups, and analyzed by Ward's method.</p></div><div><h3>Results</h3><p>We sent out 260 questionnaires and received 64 (24.6%) responses. Forty-six respondents (71.9%) said that microbiological confirmation was not important for initiation of anti-TB treatment, and that the epidemiological context and signs/symptoms suggestive of disease were most important. Sixty-one respondents (95.3%) said that the decision to continue therapy was mainly dependent on clinical improvement. A cluster of older respondents (median age: 52 years-old) who were active at a hospital or primary health care centre placed the most value on immunological test results and chest X-rays. A cluster of younger respondents (median age: 38 years-old) who were less experienced in management of TB placed more value on Interferon Gamma Release Assay (IGRA) results and chest computed tomography (CT) scans. A cluster of respondents with more experience in treating TB and working at specialized TB centres placed greater value on the clinical results and specific radiological alterations (“tree-in-bud” pattern and pleural effusion).</p></div><div><h3>Conclusion</h3><p>TB management varied according to the age, work location and experience of the clinicians. It is necessary to establish standardized guidelines used for the diagnosis and decision to treat TB in children.</p></div>","PeriodicalId":101122,"journal":{"name":"Revista Portuguesa de Pneumologia (English Edition)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rppnen.2017.06.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35364424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Pemetrexed-induced organizing pneumonia in the treatment of lung adenocarcinoma 培美曲塞诱发的组织性肺炎治疗肺腺癌

Revista Portuguesa de Pneumologia (English Edition)

Pub Date : 2017-11-01 DOI: 10.1016/j.rppnen.2017.09.003

N. China-Pereira , S. Campainha , A. Furtado , S. Conde , A. Barroso

引用次数: 0

Idiopathic pulmonary hemosiderosis: Hemorrhagic flare after 6 years of remission 特发性肺含铁血黄素沉着:缓解6年后出血性耀斑。

Revista Portuguesa de Pneumologia (English Edition)

Pub Date : 2017-11-01 DOI: 10.1016/j.rppnen.2017.07.006

P. Silva, P.G. Ferreira

引用次数: 4

Erratum to “Wood Charcoal Dust Pneumoconiosis” “炭屑尘肺病”的勘误表

Revista Portuguesa de Pneumologia (English Edition)

Pub Date : 2017-11-01 DOI: 10.1016/j.rppnen.2017.11.006

P.P.T.S. Torres , E. Marchiori , S.A. Pinto , M.F. Rabahi

引用次数: 0

Understanding patient adherence to inhaled medication: The social representations of COPD 了解患者对吸入药物的依从性:COPD的社会表征

Revista Portuguesa de Pneumologia (English Edition)

Pub Date : 2017-11-01 DOI: 10.1016/j.rppnen.2017.07.008

A. Duarte-de-Araújo , P. Teixeira , M. Figueiredo , V. Hespanhol , J. Correia-de-Sousa

引用次数: 4

Pulmonary calcified masses and gastric tumor: Incomplete Carney's triad 肺钙化肿块和胃肿瘤:不完全卡尼三联征

Revista Portuguesa de Pneumologia (English Edition)

Pub Date : 2017-11-01 DOI: 10.1016/j.rppnen.2017.09.004

B. Hochhegger , S. Camargo , E. Marchiori

引用次数: 0

More Global More Portugal 更全球化更葡萄牙

Revista Portuguesa de Pneumologia (English Edition)

Pub Date : 2017-11-01 DOI: 10.1016/j.rppnen.2017.11.005

António Morais (Editor-in-Chief)

引用次数: 0

Beneficial effects of pulmonary rehabilitation in adult asthma 肺康复对成人哮喘的有益影响

Revista Portuguesa de Pneumologia (English Edition)

Pub Date : 2017-11-01 DOI: 10.1016/j.rppnen.2017.07.004

C.M. Cruz, C. Lacerda, S. Tizón

引用次数: 1

下一页尾页

类型

全部化学•材料生命科学医学物理工程技术环境•农林材料科学地球科学法学管理学化学环境科学与生态学计算机科学教育学经济学农林科学人文科学生物学数学物理与天体物理心理学综合性期刊其他工业工程理学历史学农学文学信息工程

数据库

全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley

期刊

Revista Portuguesa de Pneumologia (English Edition)

全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.

﹀