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Subtotal vaginal hysterectomy with cervical ring preservation and cervical stump suspension to the sacrospinous ligament in women with pelvic organ prolapse: An exposed cohort study 对患有盆腔器官脱垂的妇女进行阴道次全子宫切除术,同时保留宫颈环并将宫颈残端悬吊到骶棘韧带上:暴露队列研究
Pub Date : 2024-10-30 DOI: 10.18597/rcog.4219
Jaime Andrés Machado Bernal, Andrea Lozada Ríos, Armando Rafael Gómez Castro

Objectives: To evaluate the short-term safety and efficacy of vaginal hysterectomy with cervical preservation in patients with genital prolapse stages II to IV.

Materials and methods: This is a descriptive case series study. It included women with genital prolapse stages II to IV, indicated for vaginal hysterectomy, with negative cervicovaginal cytology for malignancy, who underwent subtotal vaginal hysterectomy with suspension of the cervical stump to the sacrospinous ligament between June 1 and December 31, 2023, at a high-complexity general clinic. Sociodemographic variables and complications six months postoperatively were analyzed. The surgical technique is presented, and descriptive analysis, along with a detailed surgical technique exposition of cervical stump suspension to the sacrospinous ligament, was conducted.

Results: During the described period, 10 patients consulted, of whom eight met the inclusion criteria. The mean duration of the surgical procedure was 133 minutes. Average blood loss was 200 cc. One patient required analgesic use of pregabalin for peripheral neuropathic pain, achieving adequate postoperative pain control. No other intraoperative or postoperative complications were reported. No prolapse recurrence was observed six months postevaluation.

Conclusions: Subtotal vaginal hysterectomy with cervical stump suspension to the sacrospinous ligament is a surgical repair technique that could be considered for the management of uterine prolapse. Randomized studies comparing this technique with other management alternatives are needed to evaluate its long-term efficacy and safety.

目的评估对生殖器脱垂 II 至 IV 期患者进行保留宫颈的阴道子宫切除术的短期安全性和有效性:这是一项描述性病例系列研究。研究对象包括生殖器脱垂 II 至 IV 期、有阴道子宫切除术指征、宫颈阴道细胞学检查恶性肿瘤阴性的妇女,她们于 2023 年 6 月 1 日至 12 月 31 日期间在一家高难度综合诊所接受了阴道次全子宫切除术,并将宫颈残端悬吊至骶棘韧带。对社会人口学变量和术后六个月的并发症进行了分析。介绍了手术技巧,并进行了描述性分析,同时详细阐述了颈残端悬吊骶棘韧带的手术技巧:在所述期间,共有 10 名患者就诊,其中 8 人符合纳入标准。手术时间平均为 133 分钟。平均失血量为 200 毫升。一名患者因外周神经性疼痛需要使用普瑞巴林镇痛,术后疼痛得到了充分控制。没有其他术中或术后并发症的报告。术后六个月未发现脱垂复发:结论:阴道次全子宫切除术加宫颈残端悬吊至骶棘韧带是一种可用于治疗子宫脱垂的手术修复技术。需要对该技术与其他治疗方法进行随机研究,以评估其长期疗效和安全性。
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引用次数: 0
MAGNESIUM SULFATE: 100 years saving maternal lives. A scientific heritage of humanity 硫酸镁:拯救孕产妇生命 100 年。人类的科学遗产
Pub Date : 2024-10-25 DOI: 10.18597/rcog.4303
Alejandro Antonio Bautista-Charry

Magnesium sulfate marks 100 years in the medical management of eclampsia. Lazard, starting in May 1924 at the Los Angeles General Hospital, collected clinical evidence of its benefits on the mortality associated with pregnancy convulsions. Doses, regimens, and dilutions were analyzed, revealing therapeutic safety for both mother and fetus. By the end of the 20th century, randomized clinical trials demonstrated the clinical utility of magnesium for the following indications: treatment of eclampsia, prevention of eclampsia, and neurological protection of the brain in preterm infants less than 32 weeks of gestation, among others. This journey has been controversial among many authorities; however, the National University of Colombia and its Department of Obstetrics and Gynecology have defended the Zuspan regimen as the ideal approach for managing these patients since 1982. Through this review, we aim to present all the evidence that has established magnesium as an essential drug for reducing maternal mortality worldwide, especially in developing countries.

硫酸镁用于治疗子痫已有 100 年历史。拉扎德从 1924 年 5 月开始在洛杉矶总医院收集临床证据,证明硫酸镁对降低妊娠惊厥引起的死亡率有益。对剂量、疗程和稀释液进行了分析,结果显示对母亲和胎儿都具有治疗安全性。到 20 世纪末,随机临床试验证明了镁在以下适应症中的临床效用:治疗子痫、预防子痫、保护妊娠不足 32 周的早产儿大脑神经等。然而,自 1982 年以来,哥伦比亚国立大学及其妇产科一直将 Zuspan 方案作为治疗这些患者的理想方法。通过这篇综述,我们旨在介绍所有已证实镁是降低全球孕产妇死亡率(尤其是发展中国家孕产妇死亡率)的基本药物的证据。
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引用次数: 0
Precision surgical education 精准外科教育
Pub Date : 2024-10-23 DOI: 10.18597/rcog.4246
Luis Carlos Domínguez Torres, Neil Valentín Vega Peña, Álvaro Enrique Sanabria Quiroga

Information and data are accelerating the implementation of competency-based medical education. The adoption of precision education can contribute to this purpose. This article discusses the extent to which precision surgical education can be used in assessing the minimum reliability standards of future surgeons - given the advent of Entrustable Professional Activities - and as an option to strengthen the career trajectory of residents.

信息和数据正在加速实施以能力为基础的医学教育。精准教育的采用有助于实现这一目标。本文讨论了精准外科教育可在多大程度上用于评估未来外科医生的最低可靠性标准--鉴于 "可委托专业活动 "的出现--以及作为加强住院医师职业发展轨迹的一种选择。
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引用次数: 0
Evidence-based medicine and precision medicine: finding the balance between both 循证医学与精准医学:在两者之间寻求平衡
Pub Date : 2024-10-18 DOI: 10.18597/rcog.4333
Carlos Fernando Grillo-Ardila, Juan José Ramírez-Mosquera

Editorial.

社论
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引用次数: 0
How to best address the challenges of mental health in medical education? [如何最好地应对医学教育中的心理健康挑战]。
Pub Date : 2024-10-08 DOI: 10.18597/rcog.4332
Jorge Andrés Rubio-Romero, Hernando Gaitán-Duarte

Editorial.

社论
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引用次数: 0
Letter to the Editor regarding "Recurrent voluntary termination of pregnancy. Prevalence study and exploration of associated factors. Antioquia, Colombia, 2015 – 2021" 致编辑的信,内容涉及 "复发性自愿终止妊娠。流行率研究及相关因素探讨。哥伦比亚安蒂奥基亚,2015 - 2021年"
Pub Date : 2024-10-08 DOI: 10.18597/rcog.4274
Ariana Uceda Molina, Andrea Pari Roque
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引用次数: 0
Colombian consensus for the diagnosis, prevention, and management of Rhesus disease 哥伦比亚猕猴病诊断、预防和管理共识
Pub Date : 2024-09-30 DOI: 10.18597/rcog.4142
Jesús Andrés Benavides-Serralde, Marcela Buitrago-Leal, Saulo Molina Giraldo, Juan Pablo Benavides Calvache, Isabella Rivera Tobar, Melva Juliana López Rodríguez, Jezid Miranda, Catalina Valencia
<p><strong>Objective: </strong>To train healthcare professionals involved in the care of Rh-D negative pregnant women, with the aim of standardizing the management of Rh isoimmunization prevention, timely antenatal diagnosis of Rh disease, fetal assessment, and treatment of fetuses with Rh disease, in order to prevent adverse perinatal outcomes.</p><p><strong>Materials and methods: </strong>A group of 23 expert panelists participated in the development of the consensus through three rounds, answering a questionnaire consisting of 8 domains and 22 questions. A modified Delphi method was used until the consensus threshold among participants was reached, defined as 80% or greater agreement in responses. In the third round of the expert panel, a twenty-third question emerged, which was answered by one of the thematic leaders. The eight domains of antenatal management for Rh-D negative pregnant women were: 1) Rh-D determination, 2) initial prenatal care for Rh-D negative patients, 3) titration and periodicity of the indirect Coombs test, 4) sensitizing events, 5) administration of anti-D immunoglobulin (IgG), 6) Doppler velocimetry of the middle cerebral artery (MCA), 7) antenatal management of isoimmunized patients and anemic fetuses, and 8) timing for pregnancy termination based on different clinical scenarios. Based on these responses, and a review of international clinical practice guidelines, consensus statements were formulated, including recommendations, their justification, and adaptation to the local context.</p><p><strong>Results: </strong>The following recommendations were issued:It is suggested that Rh-D negative women of childbearing age attend a preconception consultation.It is recommended to determine maternal Rh-D status at the first contact with health services, either during the preconception consultation or at the first prenatal check-up.For Rh-D negative patients, it is recommended to determine the Rh-D status of the child's father during prenatal care as early as possible, preferably before the 28th week of gestation.For Rh-D negative primigravidas, where the father is Rh-D positive, it is suggested to: a) determine and quantify Rh-D antibodies (indirect Coombs test) during the first consultation and then quarterly, b) expand the obstetric history, with an emphasis on identifying sensitizing events, and c) provide parental counseling regarding potential risks, the need for additional tests, and the possibility of immunization during pregnancy.During prenatal care for Rh-D negative multiparous patients with previous Rh-D positive offspring, the initial approach should include: a) determining and titrating Rh-D antibodies (indirect Coombs test); b) expanding the obstetric history, focusing on sensitizing events; and c) providing parental counseling about potential risks and additional tests.After a sensitizing event, it is recommended to administer anti-D IgG within the first 72 hours at a dose of 1500 IU (300 μg). If not fea
对于 Rh-D 阴性的非同种免疫患者,共识不建议进行 MCA 多普勒超声检查。10.3. 对于间接库姆斯滴度≥ 1:16 的同种免疫患者,建议每周进行一次 MCA 多普勒超声检查。共识建议采用 MCA 多普勒胎龄收缩速度峰值中位数(MoM)≥ 1.5 倍的临界值,因为该值与胎儿贫血的相关性最佳。根据间接库姆斯氏试验滴度阈值,建议延长妊娠期,直至胎儿肺部和组织充分成熟,以提高围产期存活率:根据哥伦比亚的国情,在各级产前护理中以适当和标准化的方式处理 Rh-D 阴性孕妇、同种免疫妇女和患有 Rh 病的胎儿至关重要。本共识中提出的建议有望改善临床护理,并提高 Rh 病例的围产期健康和新生儿生活质量。
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引用次数: 0
Economic analysis of the use of the Flt-1/PlGF preeclampsia ratio compared to the standard of care in Uruguay 在乌拉圭使用 Flt-1/PlGF 先兆子痫比值与标准护理相比的经济分析
Pub Date : 2024-09-25 DOI: 10.18597/rcog.4148
Gonzalo Guiñazú, Giselle Tomasso, Gerardo Vitureira, Grazzia Rey, Verónica Fiol, Leonardo Sosa, Osvaldo Ulises Garay

Objectives: Preeclampsia (PE) is a pregnancyrelated hypertensive disorder that can lead to severe complications and adverse maternal and fetal outcomes. This study aimed to estimate the economic impact of integrating the sFlt-1/PlGF ratio into Uruguay's healthcare system as part of routine clinical practice for diagnosing.

Material and methods: A decision tree model was used to estimate the annual economic impact on the Uruguayan healthcare system for a hypothetical cohort of women with suspected PE. This included relevant costs associated with diagnosis, monitoring, and treatment from the initial presentation of suspected PE until childbirth. The study analyzed the annual costs under two scenarios: the standard of care and a scenario incorporating the sFlt-1/PlGF ratio for PE, using 2022 as the reference year. Various deterministic and probabilistic sensitivity analyses were performed.

Results: The economic model estimated that the implementation of the sFlt-1/PlGF ratio could save the Uruguayan healthcare system $95,432,678 Uruguayan pesos (2,320,269 United States Dollars [USD]) annually, representing a 5 % reduction in costs compared with the standard of care. These savings were primarily due to a reduction in hospitalizations of women with suspected PE. The estimated economic impact equated to an annual net saving of approximately $10,602 Uruguayan pesos (258 USD) per patient.

Conclusions: The introduction of the sFlt-1/PlGF ratio into the Uruguayan healthcare system is likely to generate savings due to the optimization of the management of hospitalizations for women with suspected preeclampsia (PE). However, the potential for savings will primarily depend on the current hospitalization rate of these women (the efficiency of managing high-risk PE pregnancies) and the length of stay for hospitalized women.

目的:子痫前期(PE)是一种与妊娠有关的高血压疾病,可导致严重的并发症以及不良的母体和胎儿结局。本研究旨在估算将 sFlt-1/PlGF 比值纳入乌拉圭医疗保健系统作为常规临床实践诊断的一部分所产生的经济影响:采用决策树模型估算了疑似 PE 患者的假定队列对乌拉圭医疗保健系统的年度经济影响。这包括从最初出现疑似 PE 到分娩期间与诊断、监测和治疗相关的费用。该研究分析了两种情景下的年度成本:标准护理情景和结合 sFlt-1/PlGF 比值的 PE 情景,以 2022 年为参照年。还进行了各种确定性和概率敏感性分析:经济模型估计,实施 sFlt-1/PlGF 比值每年可为乌拉圭医疗系统节省 95,432,678 乌拉圭比索(2,320,269 美元),与标准治疗相比,成本降低了 5%。节省费用的主要原因是减少了疑似 PE 妇女的住院次数。估计的经济影响相当于每位患者每年净节省约 10,602 乌拉圭比索(258 美元):在乌拉圭医疗保健系统中引入 sFlt-1/PlGF 比值很可能会因优化疑似子痫前期(PE)妇女的住院管理而节省费用。不过,节省费用的可能性主要取决于这些妇女目前的住院率(管理高危子痫前期妊娠的效率)和住院妇女的住院时间。
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引用次数: 0
Reply to the letter to the Editor about "Recurrent voluntary termination of pregnancy. Prevalence study and exploration of associated factors. Antioquia, Colombia, 2015-2021" 回复致编辑的关于 "反复自愿终止妊娠。流行率研究及相关因素探讨。哥伦比亚安蒂奥基亚,2015-2021"
Pub Date : 2024-09-10 DOI: 10.18597/rcog.4314
Freddy Andrés Barrios-Arroyave, Laura Andrea González-Pérez

Reply to the letter to the Editor

回复致编辑的信
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引用次数: 0
Prevalence, characterization, and risk factors of gestational anemia in Quindío, Colombia, 2018-2023 2018-2023 年哥伦比亚金迪奥省妊娠贫血的患病率、特征和风险因素
Pub Date : 2024-09-09 DOI: 10.18597/rcog.4202
Franklin José Espitia De La Hoz, Lilian Orozco Santiago

Objectives: To describe the prevalence and characterize gestational anemia in women attending prenatal care in the department of Quindío, Colombia, and to identify associated risk factors.

Material and methods: An analytical crosssectional study was conducted. Out of 1,003 pregnant women, 307 were selected. The study included pregnant women aged 18 years or older who attended a prenatal care program at three high-complexity private institutions in Armenia (Quindío, Colombia) from 2018 to 2023, providing a five-year observation window. Pregnant women with a diagnosis of fetal malformations and hemolytic disease, those who changed healthcare centers, or moved out of Quindío were excluded.

Results: The mean age of the participants was 28.14 ± 5.27 years. The prevalence of gestational anemia was identified as 26.38 %, with an average hemoglobin level of 9.82 ± 1.74 g/dL. Of these, 12.37 % had hemoglobin levels of 10.1-10.9 g/dL (mild anemia), 8.46 % had levels of 7.1-10.0 g/dL (moderate anemia), and 5.53 % had levels below 7.0 g/dL (severe anemia). In the third trimester, the prevalence of anemia increased to 41.97 % (n = 34/81), with 91.35 % (n = 74/81) of cases being iron-deficiency anemia. A BMI of < 18.5 (OR: 15.46; 95 % CI: 7.13-28.59), multiple pregnancy (OR: 9.73; 95 % CI: 1.49-26.83), and a history of pregestational anemia (OR: 7.43; 95 % CI: 4.52-9.13) were associated with gestational anemia.

Conclusions: The prevalence of gestational anemia is over 25 % and increases in the third trimester. It is important to identify risk factors during preconception evaluation and prenatal care.

摘要描述哥伦比亚金迪奥省接受产前护理的妇女中妊娠贫血的发生率和特征,并确定相关的风险因素:进行了一项横断面分析研究。从 1 003 名孕妇中选取了 307 名。研究对象包括 2018 年至 2023 年期间在亚美尼亚(哥伦比亚金迪奥省)三家高复杂性私立机构参加产前护理项目的 18 岁或以上孕妇,观察期为五年。排除了诊断出胎儿畸形和溶血性疾病的孕妇、更换医疗中心的孕妇或搬离金迪奥的孕妇:参与者的平均年龄为 28.14±5.27 岁。妊娠贫血患病率为 26.38%,平均血红蛋白水平为 9.82 ± 1.74 g/dL。其中,12.37%的孕妇血红蛋白水平为 10.1-10.9 g/dL(轻度贫血),8.46%的孕妇血红蛋白水平为 7.1-10.0 g/dL(中度贫血),5.53%的孕妇血红蛋白水平低于 7.0 g/dL(重度贫血)。妊娠三个月时,贫血发生率增至 41.97%(34/81),其中 91.35%(74/81)为缺铁性贫血。体重指数小于 18.5(OR:15.46;95 % CI:7.13-28.59)、多胎妊娠(OR:9.73;95 % CI:1.49-26.83)和孕前贫血史(OR:7.43;95 % CI:4.52-9.13)与妊娠贫血有关:结论:妊娠贫血的发病率超过 25%,并在妊娠三个月时有所增加。在孕前评估和产前护理中识别风险因素非常重要。
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引用次数: 0
期刊
Revista colombiana de obstetricia y ginecologia
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