Pub Date : 2023-01-01DOI: 10.54646/bijcroo.2023.34
Sujit Kumar Biswas, Nasimul Gani Chowdhury, Mahbubul Alam, Soma Rani Roy, Abdul Matin Bhuiyan, Zubaida Noor
Aim: To discuss the surgical outcome of the persistent pupillary membrane (PPM), which is a rare entity. Case report: A female child aged seven and a half years has been reported to have had reduced vision in her right eye since birth. Her vision was counting fingers; after pupillary dilation, her vision improved to 6/24. A supranasal incision in the cornea was constructed under general anesthesia with a keratome of 3.2 mm size. A dispersive viscoelastic substance was introduced into the anterior chamber. The strands were excised with an iris scissor from their junction at the collarette. The viscoelastic material was removed, and a suture was placed. The post-operative patient was treated with cycloplegic, moxifloxacin, and dexamethasone eye drops. The pre- and post-operative periods were uneventful. After one and a half months, the patient’s vision improved to 6/9 with a refraction +0.50 DS with +1.00 Cyl at 1100. Conclusion: Pupilloplasty with excision of iris strands of PPM is relatively a safe procedure and might improve visual acuity.
{"title":"Persistent pupillary membrane: a rare case and its surgical management","authors":"Sujit Kumar Biswas, Nasimul Gani Chowdhury, Mahbubul Alam, Soma Rani Roy, Abdul Matin Bhuiyan, Zubaida Noor","doi":"10.54646/bijcroo.2023.34","DOIUrl":"https://doi.org/10.54646/bijcroo.2023.34","url":null,"abstract":"Aim: To discuss the surgical outcome of the persistent pupillary membrane (PPM), which is a rare entity. Case report: A female child aged seven and a half years has been reported to have had reduced vision in her right eye since birth. Her vision was counting fingers; after pupillary dilation, her vision improved to 6/24. A supranasal incision in the cornea was constructed under general anesthesia with a keratome of 3.2 mm size. A dispersive viscoelastic substance was introduced into the anterior chamber. The strands were excised with an iris scissor from their junction at the collarette. The viscoelastic material was removed, and a suture was placed. The post-operative patient was treated with cycloplegic, moxifloxacin, and dexamethasone eye drops. The pre- and post-operative periods were uneventful. After one and a half months, the patient’s vision improved to 6/9 with a refraction +0.50 DS with +1.00 Cyl at 1100. Conclusion: Pupilloplasty with excision of iris strands of PPM is relatively a safe procedure and might improve visual acuity.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135600490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.54646/bijcroo.2023.35
Roshni Majumder, Vishal Biswas
Aim: To evaluate and analyze the management outcomes of children diagnosed with refractive accommodative esotropia. Methods: The medical records of 78 patients, who had cycloplegic correction for esotropia correction at the time of their first appointment, were thoroughly reviewed. The initial and latest visits’ cycloplegic refraction, deviation for distance and near with and without spectacles in place, stereoacuity, age of onset, management pattern, presence of anisometropia, and changes in hyperopia during the course of the research were among the factors examined. Results: The inclusion criteria were met by 78 participants in total. The mean age of participants was 5.3 ± 2.4 years. The average follow-up time was 3.1 years. Fully refractive accommodative esotropia was found in 89.74% of the patients. During the follow-up period, the mean cycloplegic refraction (diopters, spherical equivalent) remained steady. The average yearly change in refraction was 0.03 D in the right eye and 0.02 D in the left eye. Stereopsis was identified in 94.87% of patients on the first visit and improved on the second visit. Conclusion: Current management techniques for this condition result in a considerable reduction in amblyopia prevalence when compared to the prevalence upon presentation. The degree of hyperopia, on the other hand, remains unchanged, with little hope of becoming free of spectacles. It should be noted that long-term full-time spectacle use may affect emmetropization. It is likely that children will be prone to remain hyperopic.
{"title":"Current scenario of refractive accommodative esotropia management in a tertiary eye care center: A retrospective study","authors":"Roshni Majumder, Vishal Biswas","doi":"10.54646/bijcroo.2023.35","DOIUrl":"https://doi.org/10.54646/bijcroo.2023.35","url":null,"abstract":"Aim: To evaluate and analyze the management outcomes of children diagnosed with refractive accommodative esotropia. Methods: The medical records of 78 patients, who had cycloplegic correction for esotropia correction at the time of their first appointment, were thoroughly reviewed. The initial and latest visits’ cycloplegic refraction, deviation for distance and near with and without spectacles in place, stereoacuity, age of onset, management pattern, presence of anisometropia, and changes in hyperopia during the course of the research were among the factors examined. Results: The inclusion criteria were met by 78 participants in total. The mean age of participants was 5.3 ± 2.4 years. The average follow-up time was 3.1 years. Fully refractive accommodative esotropia was found in 89.74% of the patients. During the follow-up period, the mean cycloplegic refraction (diopters, spherical equivalent) remained steady. The average yearly change in refraction was 0.03 D in the right eye and 0.02 D in the left eye. Stereopsis was identified in 94.87% of patients on the first visit and improved on the second visit. Conclusion: Current management techniques for this condition result in a considerable reduction in amblyopia prevalence when compared to the prevalence upon presentation. The degree of hyperopia, on the other hand, remains unchanged, with little hope of becoming free of spectacles. It should be noted that long-term full-time spectacle use may affect emmetropization. It is likely that children will be prone to remain hyperopic.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"113 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135009034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The linear sebaceous nevus is one of a variety of epidermal nevi, which is a congenital ectodermal hamartoma that occurs due to post-zygotic mosaic mutation. Such sebaceous nevus is one of the commonest nevi, and up to 30% are associated with syndromic associations, which are rare. After cutaneous manifestation, central nervous system and ocular anomalies are common and found in almost every case. Multiorgan involvement can lead to various minor or major morbidities. Adequate knowledge and a high degree of suspicion can identify this rare disease and can minimize unwanted morbidity.
{"title":"Linear nevus sebaceous syndrome with bilateral ocular involvement in a Bangladeshi child: A case report with literature review","authors":"Soma Rani Roy, Sujit Kumar Biswas, Fahmida Hoque, Md. Sazzad Kader","doi":"10.54646/bijcroo.2023.33","DOIUrl":"https://doi.org/10.54646/bijcroo.2023.33","url":null,"abstract":"The linear sebaceous nevus is one of a variety of epidermal nevi, which is a congenital ectodermal hamartoma that occurs due to post-zygotic mosaic mutation. Such sebaceous nevus is one of the commonest nevi, and up to 30% are associated with syndromic associations, which are rare. After cutaneous manifestation, central nervous system and ocular anomalies are common and found in almost every case. Multiorgan involvement can lead to various minor or major morbidities. Adequate knowledge and a high degree of suspicion can identify this rare disease and can minimize unwanted morbidity.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"121 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135600819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.54646/bijcroo.2023.32
Vishal Biswas, Roshni Majumder
Aim: This case study demonstrates the management options for fusional vergence dysfunction (FVD) and uncorrected myopia. Background: Binocular vision disorder with abnormalities in fusional vergence dynamics is referred to as “fusional vergence dysfunction (FVD).” A patient with FVD has asthenopic symptoms, no refractive error, healthy eyes, normal accommodative functions, a normal accommodative convergence/accommodation ratio, and normal distant and near phoria status. Case presentation: A 19-year-old female diagnosed to have FVD along with simple myopia presented to the clinic with a complaint of asthenopic symptoms. Complete vergence-related and accommodation-related vision therapies were advised and provided. After 2 months from the initial presentation, the patient successfully recovered from the existing condition. Conclusion: Uncorrected myopia with FVD was determined based on the patient’s complaint and the results of the examination. The condition was treated with vision therapy and a distance optical correction. An office-based and home-based program can successfully cure FVD.
{"title":"A case of fusional vergence disorder associated with myopia","authors":"Vishal Biswas, Roshni Majumder","doi":"10.54646/bijcroo.2023.32","DOIUrl":"https://doi.org/10.54646/bijcroo.2023.32","url":null,"abstract":"Aim: This case study demonstrates the management options for fusional vergence dysfunction (FVD) and uncorrected myopia. Background: Binocular vision disorder with abnormalities in fusional vergence dynamics is referred to as “fusional vergence dysfunction (FVD).” A patient with FVD has asthenopic symptoms, no refractive error, healthy eyes, normal accommodative functions, a normal accommodative convergence/accommodation ratio, and normal distant and near phoria status. Case presentation: A 19-year-old female diagnosed to have FVD along with simple myopia presented to the clinic with a complaint of asthenopic symptoms. Complete vergence-related and accommodation-related vision therapies were advised and provided. After 2 months from the initial presentation, the patient successfully recovered from the existing condition. Conclusion: Uncorrected myopia with FVD was determined based on the patient’s complaint and the results of the examination. The condition was treated with vision therapy and a distance optical correction. An office-based and home-based program can successfully cure FVD.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135600483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Central serous chorioretinopathy(CSC) is a retinal disease characterised by diminition of vision and neurosensory macular detachment. Here we present a rare case of a 50-year-old male with a history of deep vein thrombosis, who developed CSC after warfarin intake plus his two episodes of CSC developed in susequent winter seasons.
{"title":"Warfarin, Winter, and Central Serous Chorioretinopathy","authors":"A. Chauhan, Devender Kumar Sharma","doi":"10.54646/bijcroo.005","DOIUrl":"https://doi.org/10.54646/bijcroo.005","url":null,"abstract":"Central serous chorioretinopathy(CSC) is a retinal disease characterised by diminition of vision and neurosensory macular detachment. Here we present a rare case of a 50-year-old male with a history of deep vein thrombosis, who developed CSC after warfarin intake plus his two episodes of CSC developed in susequent winter seasons.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121293533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We report an accidental finding of a classic Y shaped sutural(congenital) cataract in a 15-year-old female who came for routine ocular checkup.
我们报告一个意外发现的经典Y形缝合线(先天性)白内障在一个15岁的女性谁来进行常规眼科检查。
{"title":"Intriguing Images/Cases: Alphabet Opacity (Sutural Cataract)","authors":"A. Chauhan, Devender Kumar Sharma","doi":"10.54646/bijcroo.009","DOIUrl":"https://doi.org/10.54646/bijcroo.009","url":null,"abstract":"We report an accidental finding of a classic Y shaped sutural(congenital) cataract in a 15-year-old female who came for routine ocular checkup.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"5 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120931062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Retinoblastoma is the most common primary intraocular tumor in children with an incidence of 1: 16,000 to 18,000 live birth. Every year worldwide newly detected cases are about 8000 and in India about 1400. It represents 11% of cancer that develop in the first year of life. Current revolutionary management strategy has increased the survival rate of retinoblastoma above 95% in developed country and it is the highest among all pediatric cancer. But still it is a deadly cancer worldwide. Survival from retinoblastoma based on income >90% vs 40% (in high to low income countries). Occurrence of metastases is higher in low-income countries (32% vs 12% in middle-income). Forty three (43%) of global burden lives in 6 countries of Asia (India, China, Indonesia, Pakistan, Bangladesh & Philippines). Mortality rate varies in different continents. An estimated worldwide death rate is more than 40% and most of them from Asia and Africa. Bangladesh is one of the developing countries of the South- East Asia region and retinoblastoma constitutes 83% of all pediatric cancer bellow 4 years of age. For proper management of retinoblastoma with an international standard, establishment of retinoblastoma center consisting of Ocular oncologist, Clinical oncologist, Radiation oncologist, Pediatrician, Oculoplastic surgeon, Retina specialist, Pediatric ophthalmologist, and Ocularist is needed. Management include proper diagnosis, treatment of the disease, genetic counseling, regular follow up, rehabilitation of survivor and screening of sibling. Chittagong Eye Infirmary & Training Complex which is a tertiary center and one of the referral centers of the Bangladesh is treating retinoblastoma since its inception. Due to demand of time the hospital has been reorganized the various facilities to serve retinoblastoma patients with a team approach from 2017. From January 2017 to March 2022 total 304 patients were diagnosed. Among them 132 received VEC (Vincrisrine, Etoposide, Carbplatin) chemotherapy from this center and 79 underwent enucleation with long optic nerve. The hospitals also screen sibling, provide visual and psycho-social rehabilitation of the RB survivors and run awareness program in community level.
视网膜母细胞瘤是儿童最常见的原发性眼内肿瘤，其发生率为1.16万至1.8万活产婴儿。全世界每年新发现的病例约为8000例，印度约为1400例。它占出生后第一年发生的癌症的11%。目前革命性的治疗策略已使发达国家视网膜母细胞瘤的存活率提高到95%以上，是所有儿童癌症中最高的。但它仍然是世界范围内致命的癌症。基于收入的视网膜母细胞瘤存活率>90% vs 40%(在高收入国家和低收入国家)。转移的发生率在低收入国家较高(32%对12%的中等收入国家)。全球负担的43%生活在6个亚洲国家(印度、中国、印度尼西亚、巴基斯坦、孟加拉国和菲律宾)。各大洲的死亡率各不相同。据估计，全世界的死亡率超过40%，其中大多数来自亚洲和非洲。孟加拉国是东南亚地区的发展中国家之一，视网膜母细胞瘤占4岁以下儿童癌症的83%。为使视网膜母细胞瘤的治疗达到国际标准，需要建立由眼科肿瘤学家、临床肿瘤学家、放射肿瘤学家、儿科医生、眼整形外科医生、视网膜专科医生、儿科眼科医生和眼科医生组成的视网膜母细胞瘤中心。管理包括适当的诊断、治疗疾病、遗传咨询、定期随访、幸存者康复和兄弟姐妹筛查。吉大港眼科医院和培训中心是孟加拉国的三级中心和转诊中心之一，自成立以来一直在治疗视网膜母细胞瘤。由于时间的需要，医院从2017年开始对各种设施进行重组，以团队方式为视网膜母细胞瘤患者提供服务。2017年1月至2022年3月共诊断304例患者。其中132例接受长春新碱、依托泊苷、卡铂VEC化疗，79例行长视神经去核术。医院还对兄弟姐妹进行筛查，为RB幸存者提供视觉和心理社会康复，并在社区一级开展宣传项目。
{"title":"Establishment of “Retinoblastoma Center” in A Tertiary Eye Care Center of Bangladesh – A New Hope for Retinoblastoma Patients","authors":"S. Roy, Murtuza Nuruddin, M. Osmani","doi":"10.54646/bijcroo.012","DOIUrl":"https://doi.org/10.54646/bijcroo.012","url":null,"abstract":"Retinoblastoma is the most common primary intraocular tumor in children with an incidence of 1: 16,000 to 18,000 live birth. Every year worldwide newly detected cases are about 8000 and in India about 1400. It represents 11% of cancer that develop in the first year of life. Current revolutionary management strategy has increased the survival rate of retinoblastoma above 95% in developed country and it is the highest among all pediatric cancer. But still it is a deadly cancer worldwide. Survival from retinoblastoma based on income >90% vs 40% (in high to low income countries). Occurrence of metastases is higher in low-income countries (32% vs 12% in middle-income). Forty three (43%) of global burden lives in 6 countries of Asia (India, China, Indonesia, Pakistan, Bangladesh & Philippines). Mortality rate varies in different continents. An estimated worldwide death rate is more than 40% and most of them from Asia and Africa. Bangladesh is one of the developing countries of the South- East Asia region and retinoblastoma constitutes 83% of all pediatric cancer bellow 4 years of age. For proper management of retinoblastoma with an international standard, establishment of retinoblastoma center consisting of Ocular oncologist, Clinical oncologist, Radiation oncologist, Pediatrician, Oculoplastic surgeon, Retina specialist, Pediatric ophthalmologist, and Ocularist is needed. Management include proper diagnosis, treatment of the disease, genetic counseling, regular follow up, rehabilitation of survivor and screening of sibling. Chittagong Eye Infirmary & Training Complex which is a tertiary center and one of the referral centers of the Bangladesh is treating retinoblastoma since its inception. Due to demand of time the hospital has been reorganized the various facilities to serve retinoblastoma patients with a team approach from 2017. From January 2017 to March 2022 total 304 patients were diagnosed. Among them 132 received VEC (Vincrisrine, Etoposide, Carbplatin) chemotherapy from this center and 79 underwent enucleation with long optic nerve. The hospitals also screen sibling, provide visual and psycho-social rehabilitation of the RB survivors and run awareness program in community level.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126247197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Context: Dry Eye Disease is a multifaceted disorder caused by a variety of factors ranging from age to demographic profile. Radiation-induced dry eye disease is a relatively unexplored domain of this disease. Aim: To explore the various factors contributing to dry eye disease in patients receiving radiation therapy for head and neck malignancies with a fixed dose and duration of radiotherapy. Settings and design: A cross-sectional study conducted at a tertiary healthcare centre during a period of 1 year. Method and material: The study included 101 patients with head and neck malignancies who received a 60-Gray (Gy) dose of radiotherapy over a duration of 30 weeks. Patients were evaluated for signs and symptoms of dry eye on day 30 after completing their radiotherapy cycles using slit lamp biomicroscopy and various other tests for dry eye and compared with age, gender, location of malignancy, and adjunctive chemotherapy. Results: Out of a total of 101 patients, 45% had mild dry eye disease. 44–45% of mild dry eye disease was seen in the age groups of 20–50 and 51–80 years. The incidence of mild-to-moderate dry eye disease was almost similar (47% and 50 %) in both genders. The incidence of severe dry eye was seen in only 1% of patients. Dry eye disease was more severe in malignancies located closer to the orbit. The use of cisplatin as an adjunctive chemotherapy agent proved to be a risk factor for dry eye disease. Conclusion: Intensity-modulated radiotherapy is not enough to prevent the development of dry eye disease. A close and strict follow-up with an opthalmologist is essential for its prevention and early management.
{"title":"A Clinical Study of Intensity-Modulated Radiotherapy-Induced Dry Eye Disease in Head and Neck Malignancies","authors":"S. Thatte, Ashima Monga, Y. Goyal","doi":"10.54646/bijcroo.020","DOIUrl":"https://doi.org/10.54646/bijcroo.020","url":null,"abstract":"Context: Dry Eye Disease is a multifaceted disorder caused by a variety of factors ranging from age to demographic profile. Radiation-induced dry eye disease is a relatively unexplored domain of this disease. Aim: To explore the various factors contributing to dry eye disease in patients receiving radiation therapy for head and neck malignancies with a fixed dose and duration of radiotherapy. Settings and design: A cross-sectional study conducted at a tertiary healthcare centre during a period of 1 year. Method and material: The study included 101 patients with head and neck malignancies who received a 60-Gray (Gy) dose of radiotherapy over a duration of 30 weeks. Patients were evaluated for signs and symptoms of dry eye on day 30 after completing their radiotherapy cycles using slit lamp biomicroscopy and various other tests for dry eye and compared with age, gender, location of malignancy, and adjunctive chemotherapy. Results: Out of a total of 101 patients, 45% had mild dry eye disease. 44–45% of mild dry eye disease was seen in the age groups of 20–50 and 51–80 years. The incidence of mild-to-moderate dry eye disease was almost similar (47% and 50 %) in both genders. The incidence of severe dry eye was seen in only 1% of patients. Dry eye disease was more severe in malignancies located closer to the orbit. The use of cisplatin as an adjunctive chemotherapy agent proved to be a risk factor for dry eye disease. Conclusion: Intensity-modulated radiotherapy is not enough to prevent the development of dry eye disease. A close and strict follow-up with an opthalmologist is essential for its prevention and early management.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131693109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study examined the mobility performance in retinitis pigmentosa (RP) under different simulation lighting conditions. A total of twenty-one subjects with RP and twenty-one age-matched controls were enrolled. Preferred Walking Speed (PWS) were determined using a simple mobility course at 61 cd/m2 while Percentage of Preferred Walking Speed (PPWS) and error score were determined at five different illumination level which were 62, 47, 20, 6 and 1 cd/m2 using a complex mobility course. RP and normal people had similar mobility performances in simple mobility situations at a constant high light level. In lower light levels as well as in complex mobility situations, RP subjects demonstrated markedly reduced mobility performance. The relationship between PPWS and luminance was linear, with the PPWS decreasing significantly when the mobility course luminance dropped below the illumination of 20 cd/m2 . The Error score was also noted to be linearly related to log luminance. A luminance level of 20 cd/m2 may provide a useful decision point in setting indoor light levels for clinical mobility courses.
{"title":"Mobility Performance in Retinitis Pigmentosa Under Different Lighting Simulation Conditions","authors":"R. Omar","doi":"10.54646/bijcroo.010","DOIUrl":"https://doi.org/10.54646/bijcroo.010","url":null,"abstract":"This study examined the mobility performance in retinitis pigmentosa (RP) under different simulation lighting conditions. A total of twenty-one subjects with RP and twenty-one age-matched controls were enrolled. Preferred Walking Speed (PWS) were determined using a simple mobility course at 61 cd/m2 while Percentage of Preferred Walking Speed (PPWS) and error score were determined at five different illumination level which were 62, 47, 20, 6 and 1 cd/m2 using a complex mobility course. RP and normal people had similar mobility performances in simple mobility situations at a constant high light level. In lower light levels as well as in complex mobility situations, RP subjects demonstrated markedly reduced mobility performance. The relationship between PPWS and luminance was linear, with the PPWS decreasing significantly when the mobility course luminance dropped below the illumination of 20 cd/m2 . The Error score was also noted to be linearly related to log luminance. A luminance level of 20 cd/m2 may provide a useful decision point in setting indoor light levels for clinical mobility courses.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114223593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Paoli, L. Michelin, F. Vassallo, Luigi Ciullo, P. Brusini, L. Torelli
Purpose Malfunction of the lymphatic or glymphatic system recently shown in the brain, seems to play an important role in central neurodegenerative pathologies through a build-up of neurotoxins. Recent studies have shown functional links between aqueous humour and cerebrospinal fluid via the glymphatic system, offering new perspectives and unifying theories on the vascular, biomechanical and biochemical causes of chronic and open angle glaucoma (POAG). The aim of this randomized pilot study is to compare the variations in intraocular pressure between 20 cases of compensated POAG under pharmacological therapy and 20 glaucoma patients undergoing osteopathic treatment, hypothesizing that this manipulation can influence intraocular pressure. Materials and Methods The 40 patients under study, all covered by the Helsinki convention, were randomly divided into 2 groups (treated group or TG and control group or CG). The 40 patients were chosen from compensated glaucoma sufferers, who required neither changes in therapy nor operations which would affect their eye pressure which was measured both before and after manipulative osteopathic treatment scheduled into 4 sessions at intervals of 7.3 and 150 days, then compared with the control group (20 patients) who were undergoing pharmacological treatment only. Results The average IOP in the TG was compared with the CG throughout the entire treatment cycle showing a statistically inconclusive reduction in the right eye RE P-value (0.0561), while for the left eye a significant effect was shown LE (0.0073). The difference between the reduction in IOP between TG and CG was observable 10 months after the first session or rather 5 months after the last, and demonstrable during a check-up 13 months after the beginning of the study, or rather 8 months in absence of treatment with a highly significant statistical p-value (0.000434). Conclusions This study has shown that manipulative osteopathic treatment can affect intraocular pressure after each session and that the pressure is significantly lower even months after the last treatment session.
{"title":"The Glymphatic System and New Etiopathogenic Hypotheses Concerning Glaucoma Based on Pilot Study on Glaucoma Patients Who Underwent Osteopathic Manipulative Treatment (OMT)","authors":"D. Paoli, L. Michelin, F. Vassallo, Luigi Ciullo, P. Brusini, L. Torelli","doi":"10.54646/bijcroo.007","DOIUrl":"https://doi.org/10.54646/bijcroo.007","url":null,"abstract":"Purpose Malfunction of the lymphatic or glymphatic system recently shown in the brain, seems to play an important role in central neurodegenerative pathologies through a build-up of neurotoxins. Recent studies have shown functional links between aqueous humour and cerebrospinal fluid via the glymphatic system, offering new perspectives and unifying theories on the vascular, biomechanical and biochemical causes of chronic and open angle glaucoma (POAG). The aim of this randomized pilot study is to compare the variations in intraocular pressure between 20 cases of compensated POAG under pharmacological therapy and 20 glaucoma patients undergoing osteopathic treatment, hypothesizing that this manipulation can influence intraocular pressure. Materials and Methods The 40 patients under study, all covered by the Helsinki convention, were randomly divided into 2 groups (treated group or TG and control group or CG). The 40 patients were chosen from compensated glaucoma sufferers, who required neither changes in therapy nor operations which would affect their eye pressure which was measured both before and after manipulative osteopathic treatment scheduled into 4 sessions at intervals of 7.3 and 150 days, then compared with the control group (20 patients) who were undergoing pharmacological treatment only. Results The average IOP in the TG was compared with the CG throughout the entire treatment cycle showing a statistically inconclusive reduction in the right eye RE P-value (0.0561), while for the left eye a significant effect was shown LE (0.0073). The difference between the reduction in IOP between TG and CG was observable 10 months after the first session or rather 5 months after the last, and demonstrable during a check-up 13 months after the beginning of the study, or rather 8 months in absence of treatment with a highly significant statistical p-value (0.000434). Conclusions This study has shown that manipulative osteopathic treatment can affect intraocular pressure after each session and that the pressure is significantly lower even months after the last treatment session.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128243035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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