Pub Date : 2023-01-01DOI: 10.54646/bijcroo.2023.34
Sujit Kumar Biswas, Nasimul Gani Chowdhury, Mahbubul Alam, Soma Rani Roy, Abdul Matin Bhuiyan, Zubaida Noor
Aim: To discuss the surgical outcome of the persistent pupillary membrane (PPM), which is a rare entity. Case report: A female child aged seven and a half years has been reported to have had reduced vision in her right eye since birth. Her vision was counting fingers; after pupillary dilation, her vision improved to 6/24. A supranasal incision in the cornea was constructed under general anesthesia with a keratome of 3.2 mm size. A dispersive viscoelastic substance was introduced into the anterior chamber. The strands were excised with an iris scissor from their junction at the collarette. The viscoelastic material was removed, and a suture was placed. The post-operative patient was treated with cycloplegic, moxifloxacin, and dexamethasone eye drops. The pre- and post-operative periods were uneventful. After one and a half months, the patient’s vision improved to 6/9 with a refraction +0.50 DS with +1.00 Cyl at 1100. Conclusion: Pupilloplasty with excision of iris strands of PPM is relatively a safe procedure and might improve visual acuity.
{"title":"Persistent pupillary membrane: a rare case and its surgical management","authors":"Sujit Kumar Biswas, Nasimul Gani Chowdhury, Mahbubul Alam, Soma Rani Roy, Abdul Matin Bhuiyan, Zubaida Noor","doi":"10.54646/bijcroo.2023.34","DOIUrl":"https://doi.org/10.54646/bijcroo.2023.34","url":null,"abstract":"Aim: To discuss the surgical outcome of the persistent pupillary membrane (PPM), which is a rare entity. Case report: A female child aged seven and a half years has been reported to have had reduced vision in her right eye since birth. Her vision was counting fingers; after pupillary dilation, her vision improved to 6/24. A supranasal incision in the cornea was constructed under general anesthesia with a keratome of 3.2 mm size. A dispersive viscoelastic substance was introduced into the anterior chamber. The strands were excised with an iris scissor from their junction at the collarette. The viscoelastic material was removed, and a suture was placed. The post-operative patient was treated with cycloplegic, moxifloxacin, and dexamethasone eye drops. The pre- and post-operative periods were uneventful. After one and a half months, the patient’s vision improved to 6/9 with a refraction +0.50 DS with +1.00 Cyl at 1100. Conclusion: Pupilloplasty with excision of iris strands of PPM is relatively a safe procedure and might improve visual acuity.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135600490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.54646/bijcroo.2023.35
Roshni Majumder, Vishal Biswas
Aim: To evaluate and analyze the management outcomes of children diagnosed with refractive accommodative esotropia. Methods: The medical records of 78 patients, who had cycloplegic correction for esotropia correction at the time of their first appointment, were thoroughly reviewed. The initial and latest visits’ cycloplegic refraction, deviation for distance and near with and without spectacles in place, stereoacuity, age of onset, management pattern, presence of anisometropia, and changes in hyperopia during the course of the research were among the factors examined. Results: The inclusion criteria were met by 78 participants in total. The mean age of participants was 5.3 ± 2.4 years. The average follow-up time was 3.1 years. Fully refractive accommodative esotropia was found in 89.74% of the patients. During the follow-up period, the mean cycloplegic refraction (diopters, spherical equivalent) remained steady. The average yearly change in refraction was 0.03 D in the right eye and 0.02 D in the left eye. Stereopsis was identified in 94.87% of patients on the first visit and improved on the second visit. Conclusion: Current management techniques for this condition result in a considerable reduction in amblyopia prevalence when compared to the prevalence upon presentation. The degree of hyperopia, on the other hand, remains unchanged, with little hope of becoming free of spectacles. It should be noted that long-term full-time spectacle use may affect emmetropization. It is likely that children will be prone to remain hyperopic.
{"title":"Current scenario of refractive accommodative esotropia management in a tertiary eye care center: A retrospective study","authors":"Roshni Majumder, Vishal Biswas","doi":"10.54646/bijcroo.2023.35","DOIUrl":"https://doi.org/10.54646/bijcroo.2023.35","url":null,"abstract":"Aim: To evaluate and analyze the management outcomes of children diagnosed with refractive accommodative esotropia. Methods: The medical records of 78 patients, who had cycloplegic correction for esotropia correction at the time of their first appointment, were thoroughly reviewed. The initial and latest visits’ cycloplegic refraction, deviation for distance and near with and without spectacles in place, stereoacuity, age of onset, management pattern, presence of anisometropia, and changes in hyperopia during the course of the research were among the factors examined. Results: The inclusion criteria were met by 78 participants in total. The mean age of participants was 5.3 ± 2.4 years. The average follow-up time was 3.1 years. Fully refractive accommodative esotropia was found in 89.74% of the patients. During the follow-up period, the mean cycloplegic refraction (diopters, spherical equivalent) remained steady. The average yearly change in refraction was 0.03 D in the right eye and 0.02 D in the left eye. Stereopsis was identified in 94.87% of patients on the first visit and improved on the second visit. Conclusion: Current management techniques for this condition result in a considerable reduction in amblyopia prevalence when compared to the prevalence upon presentation. The degree of hyperopia, on the other hand, remains unchanged, with little hope of becoming free of spectacles. It should be noted that long-term full-time spectacle use may affect emmetropization. It is likely that children will be prone to remain hyperopic.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"113 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135009034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The linear sebaceous nevus is one of a variety of epidermal nevi, which is a congenital ectodermal hamartoma that occurs due to post-zygotic mosaic mutation. Such sebaceous nevus is one of the commonest nevi, and up to 30% are associated with syndromic associations, which are rare. After cutaneous manifestation, central nervous system and ocular anomalies are common and found in almost every case. Multiorgan involvement can lead to various minor or major morbidities. Adequate knowledge and a high degree of suspicion can identify this rare disease and can minimize unwanted morbidity.
{"title":"Linear nevus sebaceous syndrome with bilateral ocular involvement in a Bangladeshi child: A case report with literature review","authors":"Soma Rani Roy, Sujit Kumar Biswas, Fahmida Hoque, Md. Sazzad Kader","doi":"10.54646/bijcroo.2023.33","DOIUrl":"https://doi.org/10.54646/bijcroo.2023.33","url":null,"abstract":"The linear sebaceous nevus is one of a variety of epidermal nevi, which is a congenital ectodermal hamartoma that occurs due to post-zygotic mosaic mutation. Such sebaceous nevus is one of the commonest nevi, and up to 30% are associated with syndromic associations, which are rare. After cutaneous manifestation, central nervous system and ocular anomalies are common and found in almost every case. Multiorgan involvement can lead to various minor or major morbidities. Adequate knowledge and a high degree of suspicion can identify this rare disease and can minimize unwanted morbidity.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"121 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135600819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.54646/bijcroo.2023.32
Vishal Biswas, Roshni Majumder
Aim: This case study demonstrates the management options for fusional vergence dysfunction (FVD) and uncorrected myopia. Background: Binocular vision disorder with abnormalities in fusional vergence dynamics is referred to as “fusional vergence dysfunction (FVD).” A patient with FVD has asthenopic symptoms, no refractive error, healthy eyes, normal accommodative functions, a normal accommodative convergence/accommodation ratio, and normal distant and near phoria status. Case presentation: A 19-year-old female diagnosed to have FVD along with simple myopia presented to the clinic with a complaint of asthenopic symptoms. Complete vergence-related and accommodation-related vision therapies were advised and provided. After 2 months from the initial presentation, the patient successfully recovered from the existing condition. Conclusion: Uncorrected myopia with FVD was determined based on the patient’s complaint and the results of the examination. The condition was treated with vision therapy and a distance optical correction. An office-based and home-based program can successfully cure FVD.
{"title":"A case of fusional vergence disorder associated with myopia","authors":"Vishal Biswas, Roshni Majumder","doi":"10.54646/bijcroo.2023.32","DOIUrl":"https://doi.org/10.54646/bijcroo.2023.32","url":null,"abstract":"Aim: This case study demonstrates the management options for fusional vergence dysfunction (FVD) and uncorrected myopia. Background: Binocular vision disorder with abnormalities in fusional vergence dynamics is referred to as “fusional vergence dysfunction (FVD).” A patient with FVD has asthenopic symptoms, no refractive error, healthy eyes, normal accommodative functions, a normal accommodative convergence/accommodation ratio, and normal distant and near phoria status. Case presentation: A 19-year-old female diagnosed to have FVD along with simple myopia presented to the clinic with a complaint of asthenopic symptoms. Complete vergence-related and accommodation-related vision therapies were advised and provided. After 2 months from the initial presentation, the patient successfully recovered from the existing condition. Conclusion: Uncorrected myopia with FVD was determined based on the patient’s complaint and the results of the examination. The condition was treated with vision therapy and a distance optical correction. An office-based and home-based program can successfully cure FVD.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135600483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Central serous chorioretinopathy(CSC) is a retinal disease characterised by diminition of vision and neurosensory macular detachment. Here we present a rare case of a 50-year-old male with a history of deep vein thrombosis, who developed CSC after warfarin intake plus his two episodes of CSC developed in susequent winter seasons.
{"title":"Warfarin, Winter, and Central Serous Chorioretinopathy","authors":"A. Chauhan, Devender Kumar Sharma","doi":"10.54646/bijcroo.005","DOIUrl":"https://doi.org/10.54646/bijcroo.005","url":null,"abstract":"Central serous chorioretinopathy(CSC) is a retinal disease characterised by diminition of vision and neurosensory macular detachment. Here we present a rare case of a 50-year-old male with a history of deep vein thrombosis, who developed CSC after warfarin intake plus his two episodes of CSC developed in susequent winter seasons.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121293533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We report an accidental finding of a classic Y shaped sutural(congenital) cataract in a 15-year-old female who came for routine ocular checkup.
我们报告一个意外发现的经典Y形缝合线(先天性)白内障在一个15岁的女性谁来进行常规眼科检查。
{"title":"Intriguing Images/Cases: Alphabet Opacity (Sutural Cataract)","authors":"A. Chauhan, Devender Kumar Sharma","doi":"10.54646/bijcroo.009","DOIUrl":"https://doi.org/10.54646/bijcroo.009","url":null,"abstract":"We report an accidental finding of a classic Y shaped sutural(congenital) cataract in a 15-year-old female who came for routine ocular checkup.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"5 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120931062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Retinoblastoma is the most common primary intraocular tumor in children with an incidence of 1: 16,000 to 18,000 live birth. Every year worldwide newly detected cases are about 8000 and in India about 1400. It represents 11% of cancer that develop in the first year of life. Current revolutionary management strategy has increased the survival rate of retinoblastoma above 95% in developed country and it is the highest among all pediatric cancer. But still it is a deadly cancer worldwide. Survival from retinoblastoma based on income >90% vs 40% (in high to low income countries). Occurrence of metastases is higher in low-income countries (32% vs 12% in middle-income). Forty three (43%) of global burden lives in 6 countries of Asia (India, China, Indonesia, Pakistan, Bangladesh & Philippines). Mortality rate varies in different continents. An estimated worldwide death rate is more than 40% and most of them from Asia and Africa. Bangladesh is one of the developing countries of the South- East Asia region and retinoblastoma constitutes 83% of all pediatric cancer bellow 4 years of age. For proper management of retinoblastoma with an international standard, establishment of retinoblastoma center consisting of Ocular oncologist, Clinical oncologist, Radiation oncologist, Pediatrician, Oculoplastic surgeon, Retina specialist, Pediatric ophthalmologist, and Ocularist is needed. Management include proper diagnosis, treatment of the disease, genetic counseling, regular follow up, rehabilitation of survivor and screening of sibling. Chittagong Eye Infirmary & Training Complex which is a tertiary center and one of the referral centers of the Bangladesh is treating retinoblastoma since its inception. Due to demand of time the hospital has been reorganized the various facilities to serve retinoblastoma patients with a team approach from 2017. From January 2017 to March 2022 total 304 patients were diagnosed. Among them 132 received VEC (Vincrisrine, Etoposide, Carbplatin) chemotherapy from this center and 79 underwent enucleation with long optic nerve. The hospitals also screen sibling, provide visual and psycho-social rehabilitation of the RB survivors and run awareness program in community level.
视网膜母细胞瘤是儿童最常见的原发性眼内肿瘤，其发生率为1.16万至1.8万活产婴儿。全世界每年新发现的病例约为8000例，印度约为1400例。它占出生后第一年发生的癌症的11%。目前革命性的治疗策略已使发达国家视网膜母细胞瘤的存活率提高到95%以上，是所有儿童癌症中最高的。但它仍然是世界范围内致命的癌症。基于收入的视网膜母细胞瘤存活率>90% vs 40%(在高收入国家和低收入国家)。转移的发生率在低收入国家较高(32%对12%的中等收入国家)。全球负担的43%生活在6个亚洲国家(印度、中国、印度尼西亚、巴基斯坦、孟加拉国和菲律宾)。各大洲的死亡率各不相同。据估计，全世界的死亡率超过40%，其中大多数来自亚洲和非洲。孟加拉国是东南亚地区的发展中国家之一，视网膜母细胞瘤占4岁以下儿童癌症的83%。为使视网膜母细胞瘤的治疗达到国际标准，需要建立由眼科肿瘤学家、临床肿瘤学家、放射肿瘤学家、儿科医生、眼整形外科医生、视网膜专科医生、儿科眼科医生和眼科医生组成的视网膜母细胞瘤中心。管理包括适当的诊断、治疗疾病、遗传咨询、定期随访、幸存者康复和兄弟姐妹筛查。吉大港眼科医院和培训中心是孟加拉国的三级中心和转诊中心之一，自成立以来一直在治疗视网膜母细胞瘤。由于时间的需要，医院从2017年开始对各种设施进行重组，以团队方式为视网膜母细胞瘤患者提供服务。2017年1月至2022年3月共诊断304例患者。其中132例接受长春新碱、依托泊苷、卡铂VEC化疗，79例行长视神经去核术。医院还对兄弟姐妹进行筛查，为RB幸存者提供视觉和心理社会康复，并在社区一级开展宣传项目。
{"title":"Establishment of “Retinoblastoma Center” in A Tertiary Eye Care Center of Bangladesh – A New Hope for Retinoblastoma Patients","authors":"S. Roy, Murtuza Nuruddin, M. Osmani","doi":"10.54646/bijcroo.012","DOIUrl":"https://doi.org/10.54646/bijcroo.012","url":null,"abstract":"Retinoblastoma is the most common primary intraocular tumor in children with an incidence of 1: 16,000 to 18,000 live birth. Every year worldwide newly detected cases are about 8000 and in India about 1400. It represents 11% of cancer that develop in the first year of life. Current revolutionary management strategy has increased the survival rate of retinoblastoma above 95% in developed country and it is the highest among all pediatric cancer. But still it is a deadly cancer worldwide. Survival from retinoblastoma based on income >90% vs 40% (in high to low income countries). Occurrence of metastases is higher in low-income countries (32% vs 12% in middle-income). Forty three (43%) of global burden lives in 6 countries of Asia (India, China, Indonesia, Pakistan, Bangladesh & Philippines). Mortality rate varies in different continents. An estimated worldwide death rate is more than 40% and most of them from Asia and Africa. Bangladesh is one of the developing countries of the South- East Asia region and retinoblastoma constitutes 83% of all pediatric cancer bellow 4 years of age. For proper management of retinoblastoma with an international standard, establishment of retinoblastoma center consisting of Ocular oncologist, Clinical oncologist, Radiation oncologist, Pediatrician, Oculoplastic surgeon, Retina specialist, Pediatric ophthalmologist, and Ocularist is needed. Management include proper diagnosis, treatment of the disease, genetic counseling, regular follow up, rehabilitation of survivor and screening of sibling. Chittagong Eye Infirmary & Training Complex which is a tertiary center and one of the referral centers of the Bangladesh is treating retinoblastoma since its inception. Due to demand of time the hospital has been reorganized the various facilities to serve retinoblastoma patients with a team approach from 2017. From January 2017 to March 2022 total 304 patients were diagnosed. Among them 132 received VEC (Vincrisrine, Etoposide, Carbplatin) chemotherapy from this center and 79 underwent enucleation with long optic nerve. The hospitals also screen sibling, provide visual and psycho-social rehabilitation of the RB survivors and run awareness program in community level.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126247197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Context: Dry Eye Disease is a multifaceted disorder caused by a variety of factors ranging from age to demographic profile. Radiation-induced dry eye disease is a relatively unexplored domain of this disease. Aim: To explore the various factors contributing to dry eye disease in patients receiving radiation therapy for head and neck malignancies with a fixed dose and duration of radiotherapy. Settings and design: A cross-sectional study conducted at a tertiary healthcare centre during a period of 1 year. Method and material: The study included 101 patients with head and neck malignancies who received a 60-Gray (Gy) dose of radiotherapy over a duration of 30 weeks. Patients were evaluated for signs and symptoms of dry eye on day 30 after completing their radiotherapy cycles using slit lamp biomicroscopy and various other tests for dry eye and compared with age, gender, location of malignancy, and adjunctive chemotherapy. Results: Out of a total of 101 patients, 45% had mild dry eye disease. 44–45% of mild dry eye disease was seen in the age groups of 20–50 and 51–80 years. The incidence of mild-to-moderate dry eye disease was almost similar (47% and 50 %) in both genders. The incidence of severe dry eye was seen in only 1% of patients. Dry eye disease was more severe in malignancies located closer to the orbit. The use of cisplatin as an adjunctive chemotherapy agent proved to be a risk factor for dry eye disease. Conclusion: Intensity-modulated radiotherapy is not enough to prevent the development of dry eye disease. A close and strict follow-up with an opthalmologist is essential for its prevention and early management.
{"title":"A Clinical Study of Intensity-Modulated Radiotherapy-Induced Dry Eye Disease in Head and Neck Malignancies","authors":"S. Thatte, Ashima Monga, Y. Goyal","doi":"10.54646/bijcroo.020","DOIUrl":"https://doi.org/10.54646/bijcroo.020","url":null,"abstract":"Context: Dry Eye Disease is a multifaceted disorder caused by a variety of factors ranging from age to demographic profile. Radiation-induced dry eye disease is a relatively unexplored domain of this disease. Aim: To explore the various factors contributing to dry eye disease in patients receiving radiation therapy for head and neck malignancies with a fixed dose and duration of radiotherapy. Settings and design: A cross-sectional study conducted at a tertiary healthcare centre during a period of 1 year. Method and material: The study included 101 patients with head and neck malignancies who received a 60-Gray (Gy) dose of radiotherapy over a duration of 30 weeks. Patients were evaluated for signs and symptoms of dry eye on day 30 after completing their radiotherapy cycles using slit lamp biomicroscopy and various other tests for dry eye and compared with age, gender, location of malignancy, and adjunctive chemotherapy. Results: Out of a total of 101 patients, 45% had mild dry eye disease. 44–45% of mild dry eye disease was seen in the age groups of 20–50 and 51–80 years. The incidence of mild-to-moderate dry eye disease was almost similar (47% and 50 %) in both genders. The incidence of severe dry eye was seen in only 1% of patients. Dry eye disease was more severe in malignancies located closer to the orbit. The use of cisplatin as an adjunctive chemotherapy agent proved to be a risk factor for dry eye disease. Conclusion: Intensity-modulated radiotherapy is not enough to prevent the development of dry eye disease. A close and strict follow-up with an opthalmologist is essential for its prevention and early management.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131693109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Retinoblastoma is the most common intraocular tumor of childhood and most detected cases are from Indian subcontinent. Here we explore the presentation of retinoblastoma with its histopathological features and treatment outcome in a tertiary eye care center in Bangladesh. Method: This was a retrospective study of 70 eyes of 60 patients in a ten years period from 2006 to 2016 who had met the criteria regarding demographic profile, clinical presentation, management and histopathology. Tumor was classified based on IIRC (International Intraocular Retinoblastoma Classification) for intraocular tumor and IRSS (International Retinoblastoma Staging System) for extraocular tumor by reviewing the data revealed from EUA, imaging and histopathology. Result: The mean age of presentation was (Table 1) 31.3 ± 21.68 months, range was 4 months to 96 months and the most frequent presenting age was 12 months. Fifty three percent of children presented between 13 months and 59 months. Mild male predominance was 53.3% (n = 32). Unilateral cases were 71.3% (n = 43) and 6.7% (n = 4) of patients had positive family history. The most common presenting sign was leucocoria (85%) followed by strabismus (18.3%) and proptosis (13.3%). Fifty five (91.6%) children presented with intraocular tumor and 64.9% were with Group E. Enucleation (91.6%) was the prime treatment modality and histopathological risk factor was positive in 51.7% cases among 63.3% cases of primary enucleation. Fifty percent of treated children were in regular follow up. Conclusion: Most children presented delayed and prime treatment modality was enucleation. Only half of the patients were in regular follow up. Generation of awareness, proper referral, information regarding treatment availability and early detection of cases can increase the survival rate and globe salvage.
背景:视网膜母细胞瘤是儿童最常见的眼内肿瘤，大多数发现病例来自印度次大陆。在这里，我们探讨视网膜母细胞瘤的表现，其组织病理学特征和治疗结果在三级眼科护理中心在孟加拉国。方法:对2006 - 2016年10年间符合人口统计学、临床表现、治疗和组织病理学标准的60例患者70只眼进行回顾性研究。结合EUA、影像学和组织病理学资料，根据眼内肿瘤IIRC (International Intraocular Retinoblastoma Classification)和眼外肿瘤IRSS (International Retinoblastoma分期系统)进行分类。结果:平均出现年龄为(表1)31.3±21.68个月，范围为4 ~ 96个月，最常见的出现年龄为12个月。53%的孩子在13个月到59个月之间出现。轻度男性优势为53.3% (n = 32)。单侧病例中有阳性家族史的占71.3% (n = 43)，阳性家族史的占6.7% (n = 4)。最常见的症状是白光(85%)，其次是斜视(18.3%)和眼球突出(13.3%)。以眼内肿瘤为主的患儿55例(91.6%)，其中e组占64.9%。在63.3%的原发性眼内肿瘤患者中，51.7%的患者组织病理危险因素阳性。50%接受治疗的儿童接受了定期随访。结论:多数患儿表现迟发，首选治疗方式为眼球摘除。只有一半的患者接受了定期随访。提高认识、适当转诊、提供治疗信息和早期发现病例可提高生存率和全球救助。
{"title":"Scenario of Retinoblastoma Among Bangladeshi Children – A Single Center Experience of 10 Years","authors":"Rani Roy Soma, Nuruddin Murtuza, Asgar Ali","doi":"10.54646/bijcroo.017","DOIUrl":"https://doi.org/10.54646/bijcroo.017","url":null,"abstract":"Background: Retinoblastoma is the most common intraocular tumor of childhood and most detected cases are from Indian subcontinent. Here we explore the presentation of retinoblastoma with its histopathological features and treatment outcome in a tertiary eye care center in Bangladesh. Method: This was a retrospective study of 70 eyes of 60 patients in a ten years period from 2006 to 2016 who had met the criteria regarding demographic profile, clinical presentation, management and histopathology. Tumor was classified based on IIRC (International Intraocular Retinoblastoma Classification) for intraocular tumor and IRSS (International Retinoblastoma Staging System) for extraocular tumor by reviewing the data revealed from EUA, imaging and histopathology. Result: The mean age of presentation was (Table 1) 31.3 ± 21.68 months, range was 4 months to 96 months and the most frequent presenting age was 12 months. Fifty three percent of children presented between 13 months and 59 months. Mild male predominance was 53.3% (n = 32). Unilateral cases were 71.3% (n = 43) and 6.7% (n = 4) of patients had positive family history. The most common presenting sign was leucocoria (85%) followed by strabismus (18.3%) and proptosis (13.3%). Fifty five (91.6%) children presented with intraocular tumor and 64.9% were with Group E. Enucleation (91.6%) was the prime treatment modality and histopathological risk factor was positive in 51.7% cases among 63.3% cases of primary enucleation. Fifty percent of treated children were in regular follow up. Conclusion: Most children presented delayed and prime treatment modality was enucleation. Only half of the patients were in regular follow up. Generation of awareness, proper referral, information regarding treatment availability and early detection of cases can increase the survival rate and globe salvage.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116109842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chowdhury Nasimul Gani, Biswas Sujit Kumar, A. Wahid, Hossain Dostogir, Noor Jannatun, Islam Urmi Atika
Purpose: To evaluate the visual outcome and long-term complications of intraocular lens implantation along with primary posterior capsulectomy & anterior vitrectomy in children with bilateral developmental cataract. Methods: This retrospective study was carried out on the 48 eyes of 24 children who had undergone cataract surgery under general anesthesia. Age range was 2 to 8 years. All patients underwent primary posterior capsulectomy, primary in-bag intraocular lens (IOL) implantation, irrigation-aspiration of lens debris, and anterior vitrectomy. At intervals of one week, one month, three months, and six months, every case was evaluated. After 6 months best corrected visual acuity was recorded and intraocular pressure, anterior chamber angle, optic disc, and peripheral retina were evaluated. Results: Postoperative best corrected visual acuity were 6/6 in 10.4% eyes, 6/9-6/18 in 56.3% and <6/18 in 33% eyes. Intra ocular pressures were found within normal limit (12 ± 2.09 mm of Hg) in all cases. Anterior chamber angle was normal in 44 eyes (91.7%). Peripheral retina and vitreous were normal in all cases. No significant Optic disc changes were noticed. The most common cause of decreased vision was amblyopia (79.2%) in the fellow eye due to delayed surgery. Conclusion: Amblyopia is the main cause of decreased visual recovery in children after cataract surgery. Surgical intervention in proper time results in good visual outcome
目的:评价儿童双侧发育性白内障人工晶状体植入术联合初级后囊膜和前玻璃体切除术的视力及远期并发症。方法:对24例全麻下行白内障手术的患儿48眼进行回顾性研究。年龄范围为2至8岁。所有患者均接受了初级后囊膜切除术、初级袋内人工晶状体植入术、晶状体碎片冲洗吸出术和前体玻璃体切除术。每隔一周、一个月、三个月和六个月对每个病例进行评估。6个月后记录最佳矫正视力，评估眼压、前房角、视盘、周围视网膜。结果:10.4%眼术后最佳矫正视力为6/6,56.3%眼为6/9 ~ 6/18,33%眼<6/18。所有病例眼压均在正常范围内(12±2.09 mm Hg)。前房角正常44眼(91.7%)。所有病例外周视网膜和玻璃体均正常。视盘未见明显改变。视力下降最常见的原因是由于手术延迟导致的同侧眼弱视(79.2%)。结论:弱视是儿童白内障术后视力恢复下降的主要原因。手术干预时机适当，视觉效果良好
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