Background: Retinoblastoma is the most common intraocular tumor of childhood and most detected cases are from Indian subcontinent. Here we explore the presentation of retinoblastoma with its histopathological features and treatment outcome in a tertiary eye care center in Bangladesh. Method: This was a retrospective study of 70 eyes of 60 patients in a ten years period from 2006 to 2016 who had met the criteria regarding demographic profile, clinical presentation, management and histopathology. Tumor was classified based on IIRC (International Intraocular Retinoblastoma Classification) for intraocular tumor and IRSS (International Retinoblastoma Staging System) for extraocular tumor by reviewing the data revealed from EUA, imaging and histopathology. Result: The mean age of presentation was (Table 1) 31.3 ± 21.68 months, range was 4 months to 96 months and the most frequent presenting age was 12 months. Fifty three percent of children presented between 13 months and 59 months. Mild male predominance was 53.3% (n = 32). Unilateral cases were 71.3% (n = 43) and 6.7% (n = 4) of patients had positive family history. The most common presenting sign was leucocoria (85%) followed by strabismus (18.3%) and proptosis (13.3%). Fifty five (91.6%) children presented with intraocular tumor and 64.9% were with Group E. Enucleation (91.6%) was the prime treatment modality and histopathological risk factor was positive in 51.7% cases among 63.3% cases of primary enucleation. Fifty percent of treated children were in regular follow up. Conclusion: Most children presented delayed and prime treatment modality was enucleation. Only half of the patients were in regular follow up. Generation of awareness, proper referral, information regarding treatment availability and early detection of cases can increase the survival rate and globe salvage.
背景:视网膜母细胞瘤是儿童最常见的眼内肿瘤，大多数发现病例来自印度次大陆。在这里，我们探讨视网膜母细胞瘤的表现，其组织病理学特征和治疗结果在三级眼科护理中心在孟加拉国。方法:对2006 - 2016年10年间符合人口统计学、临床表现、治疗和组织病理学标准的60例患者70只眼进行回顾性研究。结合EUA、影像学和组织病理学资料，根据眼内肿瘤IIRC (International Intraocular Retinoblastoma Classification)和眼外肿瘤IRSS (International Retinoblastoma分期系统)进行分类。结果:平均出现年龄为(表1)31.3±21.68个月，范围为4 ~ 96个月，最常见的出现年龄为12个月。53%的孩子在13个月到59个月之间出现。轻度男性优势为53.3% (n = 32)。单侧病例中有阳性家族史的占71.3% (n = 43)，阳性家族史的占6.7% (n = 4)。最常见的症状是白光(85%)，其次是斜视(18.3%)和眼球突出(13.3%)。以眼内肿瘤为主的患儿55例(91.6%)，其中e组占64.9%。在63.3%的原发性眼内肿瘤患者中，51.7%的患者组织病理危险因素阳性。50%接受治疗的儿童接受了定期随访。结论:多数患儿表现迟发，首选治疗方式为眼球摘除。只有一半的患者接受了定期随访。提高认识、适当转诊、提供治疗信息和早期发现病例可提高生存率和全球救助。
{"title":"Scenario of Retinoblastoma Among Bangladeshi Children – A Single Center Experience of 10 Years","authors":"Rani Roy Soma, Nuruddin Murtuza, Asgar Ali","doi":"10.54646/bijcroo.017","DOIUrl":"https://doi.org/10.54646/bijcroo.017","url":null,"abstract":"Background: Retinoblastoma is the most common intraocular tumor of childhood and most detected cases are from Indian subcontinent. Here we explore the presentation of retinoblastoma with its histopathological features and treatment outcome in a tertiary eye care center in Bangladesh. Method: This was a retrospective study of 70 eyes of 60 patients in a ten years period from 2006 to 2016 who had met the criteria regarding demographic profile, clinical presentation, management and histopathology. Tumor was classified based on IIRC (International Intraocular Retinoblastoma Classification) for intraocular tumor and IRSS (International Retinoblastoma Staging System) for extraocular tumor by reviewing the data revealed from EUA, imaging and histopathology. Result: The mean age of presentation was (Table 1) 31.3 ± 21.68 months, range was 4 months to 96 months and the most frequent presenting age was 12 months. Fifty three percent of children presented between 13 months and 59 months. Mild male predominance was 53.3% (n = 32). Unilateral cases were 71.3% (n = 43) and 6.7% (n = 4) of patients had positive family history. The most common presenting sign was leucocoria (85%) followed by strabismus (18.3%) and proptosis (13.3%). Fifty five (91.6%) children presented with intraocular tumor and 64.9% were with Group E. Enucleation (91.6%) was the prime treatment modality and histopathological risk factor was positive in 51.7% cases among 63.3% cases of primary enucleation. Fifty percent of treated children were in regular follow up. Conclusion: Most children presented delayed and prime treatment modality was enucleation. Only half of the patients were in regular follow up. Generation of awareness, proper referral, information regarding treatment availability and early detection of cases can increase the survival rate and globe salvage.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116109842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chowdhury Nasimul Gani, Biswas Sujit Kumar, A. Wahid, Hossain Dostogir, Noor Jannatun, Islam Urmi Atika
Purpose: To evaluate the visual outcome and long-term complications of intraocular lens implantation along with primary posterior capsulectomy & anterior vitrectomy in children with bilateral developmental cataract. Methods: This retrospective study was carried out on the 48 eyes of 24 children who had undergone cataract surgery under general anesthesia. Age range was 2 to 8 years. All patients underwent primary posterior capsulectomy, primary in-bag intraocular lens (IOL) implantation, irrigation-aspiration of lens debris, and anterior vitrectomy. At intervals of one week, one month, three months, and six months, every case was evaluated. After 6 months best corrected visual acuity was recorded and intraocular pressure, anterior chamber angle, optic disc, and peripheral retina were evaluated. Results: Postoperative best corrected visual acuity were 6/6 in 10.4% eyes, 6/9-6/18 in 56.3% and <6/18 in 33% eyes. Intra ocular pressures were found within normal limit (12 ± 2.09 mm of Hg) in all cases. Anterior chamber angle was normal in 44 eyes (91.7%). Peripheral retina and vitreous were normal in all cases. No significant Optic disc changes were noticed. The most common cause of decreased vision was amblyopia (79.2%) in the fellow eye due to delayed surgery. Conclusion: Amblyopia is the main cause of decreased visual recovery in children after cataract surgery. Surgical intervention in proper time results in good visual outcome
目的:评价儿童双侧发育性白内障人工晶状体植入术联合初级后囊膜和前玻璃体切除术的视力及远期并发症。方法:对24例全麻下行白内障手术的患儿48眼进行回顾性研究。年龄范围为2至8岁。所有患者均接受了初级后囊膜切除术、初级袋内人工晶状体植入术、晶状体碎片冲洗吸出术和前体玻璃体切除术。每隔一周、一个月、三个月和六个月对每个病例进行评估。6个月后记录最佳矫正视力，评估眼压、前房角、视盘、周围视网膜。结果:10.4%眼术后最佳矫正视力为6/6,56.3%眼为6/9 ~ 6/18,33%眼<6/18。所有病例眼压均在正常范围内(12±2.09 mm Hg)。前房角正常44眼(91.7%)。所有病例外周视网膜和玻璃体均正常。视盘未见明显改变。视力下降最常见的原因是由于手术延迟导致的同侧眼弱视(79.2%)。结论:弱视是儿童白内障术后视力恢复下降的主要原因。手术干预时机适当，视觉效果良好
{"title":"Surgical Outcome of Intraocular Lens Implantation in Children with Bilateral Developmental Cataract","authors":"Chowdhury Nasimul Gani, Biswas Sujit Kumar, A. Wahid, Hossain Dostogir, Noor Jannatun, Islam Urmi Atika","doi":"10.54646/bijcroo.015","DOIUrl":"https://doi.org/10.54646/bijcroo.015","url":null,"abstract":"Purpose: To evaluate the visual outcome and long-term complications of intraocular lens implantation along with primary posterior capsulectomy & anterior vitrectomy in children with bilateral developmental cataract. Methods: This retrospective study was carried out on the 48 eyes of 24 children who had undergone cataract surgery under general anesthesia. Age range was 2 to 8 years. All patients underwent primary posterior capsulectomy, primary in-bag intraocular lens (IOL) implantation, irrigation-aspiration of lens debris, and anterior vitrectomy. At intervals of one week, one month, three months, and six months, every case was evaluated. After 6 months best corrected visual acuity was recorded and intraocular pressure, anterior chamber angle, optic disc, and peripheral retina were evaluated. Results: Postoperative best corrected visual acuity were 6/6 in 10.4% eyes, 6/9-6/18 in 56.3% and <6/18 in 33% eyes. Intra ocular pressures were found within normal limit (12 ± 2.09 mm of Hg) in all cases. Anterior chamber angle was normal in 44 eyes (91.7%). Peripheral retina and vitreous were normal in all cases. No significant Optic disc changes were noticed. The most common cause of decreased vision was amblyopia (79.2%) in the fellow eye due to delayed surgery. Conclusion: Amblyopia is the main cause of decreased visual recovery in children after cataract surgery. Surgical intervention in proper time results in good visual outcome","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121532243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Retinoblastoma is the most common primary intraocular tumor in children with an incidence of 1:16,000 to 18,000 live birth. Worldwide newly detected cases per year are about 8000 and in India above 1400. It represents 11% of cancer that develops in the first year of life. The revolutionary management strategy has increased the survival rate of retinoblastoma above 95% in developed countries, and this rate is the highest among all pediatric cancers. But still, it is deadly cancer worldwide. Survival from retinoblastoma based on income >90% vs. 40% (in high to low-income countries). The incidence of metastasis is more in lower-income countries (32% vs. 12% in middle-income). Notably, Forty-three percent of the world’s estimated cases reside in only 6 countries in Asia (China, Indonesia, Philippines, India, Pakistan, and Bangladesh). The mortality rate varies on different continents. Worldwide estimated death from retinoblastoma is more than 40%, and most of them are from Asia and Africa. Bangladesh is one of the developing countries in the South-East Asia region, and retinoblastoma constitutes 83% of all pediatric cancer under 4 years of age. For proper management of retinoblastoma with an international standard, the establishment of a retinoblastoma center consisting of ocular oncologist, clinical oncologist, radiation oncologist, pediatrician, oculoplastic surgeon, retina specialist, pediatric ophthalmologist, and ocularist is needed. Management includes proper diagnosis, treatment of the disease, genetic counseling, regular follow-up, rehabilitation of survivors, and screening of siblings. Chittagong Eye Infirmary & Training Complex is a tertiary eye care center and one of the referral centers of Bangladesh and is treating retinoblastoma since its inception. Due to the demand of time, the hospital has been reorganized with various facilities to serve retinoblastoma patients with a team approach in 2017. From January 2017 to March 2022, a total of 304 patients were diagnosed. Among them, 132 received vincristine, etoposide, and carboplatin (VEC) chemotherapy from this center, and 79 underwent enucleation with the long optic nerve. Besides treatment, the hospital is conducting sibling screening, visual and psycho-social rehabilitation for the RB survivors, and community awareness programs.
视网膜母细胞瘤是儿童中最常见的原发性眼内肿瘤，其活产率为1:16 000至18000。全世界每年新发现的病例约为8000例，印度超过1400例。它占出生后第一年发生的癌症的11%。在发达国家，这种革命性的治疗策略使视网膜母细胞瘤的存活率提高到95%以上，是所有儿童癌症中最高的。但它仍然是世界范围内致命的癌症。基于收入的视网膜母细胞瘤存活率为90% vs. 40%(在高收入和低收入国家)。转移的发生率在低收入国家更高(32%对12%的中等收入国家)。值得注意的是，全世界估计病例的43%仅居住在亚洲6个国家(中国、印度尼西亚、菲律宾、印度、巴基斯坦和孟加拉国)。各大洲的死亡率各不相同。全世界视网膜母细胞瘤的死亡率估计超过40%，其中大多数来自亚洲和非洲。孟加拉国是东南亚地区的发展中国家之一，视网膜母细胞瘤占所有4岁以下儿童癌症的83%。为使视网膜母细胞瘤的治疗达到国际标准，需要建立一个由眼科肿瘤学家、临床肿瘤学家、放射肿瘤学家、儿科医生、眼整形外科医生、视网膜专科医生、儿童眼科医生和眼科医生组成的视网膜母细胞瘤中心。管理包括适当的诊断、疾病治疗、遗传咨询、定期随访、幸存者康复和兄弟姐妹筛查。吉大港眼科医院和培训中心是一个三级眼科保健中心，也是孟加拉国的转诊中心之一，自成立以来一直在治疗视网膜母细胞瘤。由于时间的需要，医院于2017年进行了重组，配备了各种设施，以团队方式为视网膜母细胞瘤患者提供服务。2017年1月至2022年3月，共诊断304例患者。其中132例在该中心接受长春新碱、依托泊苷、卡铂(VEC)化疗，79例视神经长段去核。除了治疗之外，医院还开展了兄弟姐妹筛查、RB幸存者的视觉和心理社会康复以及社区意识项目。
{"title":"Establishment of “Retinoblastoma center” in A Tertiary Eye Care Center of Bangladesh – A New Hope for Retinoblastoma Patients","authors":"Rani Roy Soma","doi":"10.54646/bijcroo.016","DOIUrl":"https://doi.org/10.54646/bijcroo.016","url":null,"abstract":"Retinoblastoma is the most common primary intraocular tumor in children with an incidence of 1:16,000 to 18,000 live birth. Worldwide newly detected cases per year are about 8000 and in India above 1400. It represents 11% of cancer that develops in the first year of life. The revolutionary management strategy has increased the survival rate of retinoblastoma above 95% in developed countries, and this rate is the highest among all pediatric cancers. But still, it is deadly cancer worldwide. Survival from retinoblastoma based on income >90% vs. 40% (in high to low-income countries). The incidence of metastasis is more in lower-income countries (32% vs. 12% in middle-income). Notably, Forty-three percent of the world’s estimated cases reside in only 6 countries in Asia (China, Indonesia, Philippines, India, Pakistan, and Bangladesh). The mortality rate varies on different continents. Worldwide estimated death from retinoblastoma is more than 40%, and most of them are from Asia and Africa. Bangladesh is one of the developing countries in the South-East Asia region, and retinoblastoma constitutes 83% of all pediatric cancer under 4 years of age. For proper management of retinoblastoma with an international standard, the establishment of a retinoblastoma center consisting of ocular oncologist, clinical oncologist, radiation oncologist, pediatrician, oculoplastic surgeon, retina specialist, pediatric ophthalmologist, and ocularist is needed. Management includes proper diagnosis, treatment of the disease, genetic counseling, regular follow-up, rehabilitation of survivors, and screening of siblings. Chittagong Eye Infirmary & Training Complex is a tertiary eye care center and one of the referral centers of Bangladesh and is treating retinoblastoma since its inception. Due to the demand of time, the hospital has been reorganized with various facilities to serve retinoblastoma patients with a team approach in 2017. From January 2017 to March 2022, a total of 304 patients were diagnosed. Among them, 132 received vincristine, etoposide, and carboplatin (VEC) chemotherapy from this center, and 79 underwent enucleation with the long optic nerve. Besides treatment, the hospital is conducting sibling screening, visual and psycho-social rehabilitation for the RB survivors, and community awareness programs.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"88 35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130793241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.54646/bijcroo.2023.29
S. Roy, S. Biswas
A 52-year-old woman with bronchial asthma, frequent sneezing, and a skin lesion has suddenly developed poor vision for 15 days in the left eye. Her presenting vision was 6/18 and perception of light was positive in the right and left eyes, respectively, with mild pallor in the right optic disc and disc swelling in the left eye. She had a high eosinophil count, positive ANCA, and a skin biopsy in favor of Churg-Strauss disease. The patient was diagnosed with left optic neuropathy as a result of arteritis, which is a component of Churg-Strauss syndrome (CSS), and was treated with Inj. Methylprednisolone pulse therapy, followed by oral prednisolone but preceded to no perception of light in the left eye after 7 days of follow-up. Although CSS is a rare disease, routine checkup by an ophthalmologist can save vision and identify the high-risk group for proper referral to prevent unwanted morbidity and mortality.
{"title":"Churg-Strauss syndrome presented as Pseudo-Foster-Kennedy syndrome: a case report","authors":"S. Roy, S. Biswas","doi":"10.54646/bijcroo.2023.29","DOIUrl":"https://doi.org/10.54646/bijcroo.2023.29","url":null,"abstract":"A 52-year-old woman with bronchial asthma, frequent sneezing, and a skin lesion has suddenly developed poor vision for 15 days in the left eye. Her presenting vision was 6/18 and perception of light was positive in the right and left eyes, respectively, with mild pallor in the right optic disc and disc swelling in the left eye. She had a high eosinophil count, positive ANCA, and a skin biopsy in favor of Churg-Strauss disease. The patient was diagnosed with left optic neuropathy as a result of arteritis, which is a component of Churg-Strauss syndrome (CSS), and was treated with Inj. Methylprednisolone pulse therapy, followed by oral prednisolone but preceded to no perception of light in the left eye after 7 days of follow-up. Although CSS is a rare disease, routine checkup by an ophthalmologist can save vision and identify the high-risk group for proper referral to prevent unwanted morbidity and mortality.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129365259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Globe subluxation is a medical emergency and a frightening condition. The spontaneous subluxation is the rarest of the subluxations, with fewer than 40 cases reported to date. This condition is extremely rare in children, with the most recent reported age being 8 months. However, Crouzon syndrome in infants is also less reported. Here we report a case of neonatal Crouzon syndrome with spontaneous globe subluxation and its surgical management.
{"title":"Spontaneous Globe Subluxation in a Neonate: A Case Report with Literature Review","authors":"S. Roy, Md. Asrarul Hoque","doi":"10.54646/bijcroo.026","DOIUrl":"https://doi.org/10.54646/bijcroo.026","url":null,"abstract":"Globe subluxation is a medical emergency and a frightening condition. The spontaneous subluxation is the rarest of the subluxations, with fewer than 40 cases reported to date. This condition is extremely rare in children, with the most recent reported age being 8 months. However, Crouzon syndrome in infants is also less reported. Here we report a case of neonatal Crouzon syndrome with spontaneous globe subluxation and its surgical management.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133293255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
3MC syndrome is a very rare entity. It’s prevalence is unknown but most cases are reported from Middle East. First case was reported in 1978 and named as Michel syndrome and recently with other three syndromes together these syndromes are named as 3 MC syndrome. All are autosomal recessive disorder and reported from both consanguineous and non- consanguineous parents. Here we phenotypically analyzed a case presented with the features of blepharophimosis syndrome associated with craniosynostosis suggestive of Mischel syndrome which is a part of ‘3 MC syndrome’.
{"title":"Phenotypic Analysis of A Case of ‘3MC Syndrome’ with Review of Literature","authors":"Rani Roy Soma, Kader Md. Sazzad","doi":"10.54646/bijcroo.014","DOIUrl":"https://doi.org/10.54646/bijcroo.014","url":null,"abstract":"3MC syndrome is a very rare entity. It’s prevalence is unknown but most cases are reported from Middle East. First case was reported in 1978 and named as Michel syndrome and recently with other three syndromes together these syndromes are named as 3 MC syndrome. All are autosomal recessive disorder and reported from both consanguineous and non- consanguineous parents. Here we phenotypically analyzed a case presented with the features of blepharophimosis syndrome associated with craniosynostosis suggestive of Mischel syndrome which is a part of ‘3 MC syndrome’.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134262122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This case of Vogt-Koyanagi-Harada (VKH) disease underwent Aurolab Aqueous Drainage Implant (AADI) for refractory glaucoma. Later, developed postoperative (2 months) panophthalmitis characterized by sudden visual loss, moderate pain, redness, and purulent discharge. Systemic, topical, and intravitreal antibiotic therapy was started immediately, and evisceration was performed.
{"title":"Panophthalmitis After Aurolab Aqueous Drainage Implant (AADI) in Refractory Glaucoma with Vogt-Koyanagi-Harada Syndrome (VKH): A Case Report","authors":"Md Iftekher Iqbal, S. Kabir, B. Sarker","doi":"10.54646/bijcroo.022","DOIUrl":"https://doi.org/10.54646/bijcroo.022","url":null,"abstract":"This case of Vogt-Koyanagi-Harada (VKH) disease underwent Aurolab Aqueous Drainage Implant (AADI) for refractory glaucoma. Later, developed postoperative (2 months) panophthalmitis characterized by sudden visual loss, moderate pain, redness, and purulent discharge. Systemic, topical, and intravitreal antibiotic therapy was started immediately, and evisceration was performed.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"108 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129802086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A patient presented to us with post-infectious keratitis and a large anterior staphyloma in the left eye with vision as low as only the perception of light and accurately determining the projection of rays. A B-scan showed no abnormality in the posterior segment. Sclerokeratoplasty with an 11-mm graft with aniridia and aphakia was done. On 4 weeks of follow-up, intraocular pressure (IOP) was 39 mmHg on applanation tonometry, for which medical management was tried using a combination regime that was insufficient, following which a series of management approaches like trabeculectomy and Ahmed glaucoma valve (AGV) implant was done (in superotemporal quadrant). Unfortunately, recurrent exposures of the AGV tube were encountered, which were managed using different graft materials one after the other but were unsuccessful. Ultimately, AGV explantation and reinsertion at another site (in inferotemporal quadrant) was tried, which led to salvaging the eye with well controlled IOP, clear graft, and good visual function (best corrected visual acuity of 6/12p with +12.00/+1.50 × 90◦ ). The purpose of this article was to highlight that despite multiple complications encountered in a single case, a careful sequential approach, good surgical skills, and a never giving up attitude lead to excellent results.
{"title":"Management Challenge: A Case of Aniridia and Aphakia with Secondary Glaucoma in Sclerokeratoplasty","authors":"S. Thatte, Komal Jaiswal, Radhika Maheshwari","doi":"10.54646/bijcroo.027","DOIUrl":"https://doi.org/10.54646/bijcroo.027","url":null,"abstract":"A patient presented to us with post-infectious keratitis and a large anterior staphyloma in the left eye with vision as low as only the perception of light and accurately determining the projection of rays. A B-scan showed no abnormality in the posterior segment. Sclerokeratoplasty with an 11-mm graft with aniridia and aphakia was done. On 4 weeks of follow-up, intraocular pressure (IOP) was 39 mmHg on applanation tonometry, for which medical management was tried using a combination regime that was insufficient, following which a series of management approaches like trabeculectomy and Ahmed glaucoma valve (AGV) implant was done (in superotemporal quadrant). Unfortunately, recurrent exposures of the AGV tube were encountered, which were managed using different graft materials one after the other but were unsuccessful. Ultimately, AGV explantation and reinsertion at another site (in inferotemporal quadrant) was tried, which led to salvaging the eye with well controlled IOP, clear graft, and good visual function (best corrected visual acuity of 6/12p with +12.00/+1.50 × 90◦ ). The purpose of this article was to highlight that despite multiple complications encountered in a single case, a careful sequential approach, good surgical skills, and a never giving up attitude lead to excellent results.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128913354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Md Iftekher Iqbal, Fariah Osman, Md. Firoz Kabir, S. Parvez
Purpose: The aim of this study is to assess the efficacy among patients undergoing pterygium excision and conjunctival autograft utilizing autologous blood or sutures. Methods: A randomized controlled trial of 1 year and 5 months, with 60 eyes from 60 patients having primary nasal pterygium. As indicated by inclusion criteria, they were chosen and randomized into two arms for conjunctival autograft: treated arm A (30) with autologous blood and arm B (30) with stitches (10-0 monofilament nylon). Preoperative and postoperative results were assessed and analyzed statistically. Follow-up was done at first, seventh, 1-month, 3-month, and half-year postoperative days. Resulting factors were total surgical time, postoperative comfort, graft stability, and recurrence. Results: 60 patients; mean age of 46.77 ± 7.04 (SD) in arm A (30) and 46.17±7.53 (SD) in arm B (30). In arm A, 22 males (73.3%) and 8 females (26.7%) where arm B had 20 males (66.7%) and 10 females (33.3%). Total surgical time in arm A was 24.73 ± 3.69 (SD) minutes and in arm B was 32.23 ± 4.59 (SD) minutes (p < 0.001). Follow-up at the 1st and 7th POD showed significant discomfort in arm B (mean ranks 41.82 and 40.62) compared to arm A (mean ranks 19.18 and 20.38), respectively (p < 0.001). At 1st POD, only 3 (10%) graft retractions in arm A. Within 6 months of follow-up, all grafts were stable; 1 (3.3%) recurrence and 1 (3.3%) granuloma in arm B only. Conclusion: In primary pterygium surgery, autologous blood showed excellent postoperative results with no recurrence and reduced surgical time. So, it seems to be an effective surgical means to treat primary pterygium.
{"title":"Efficacy of Autologous Blood Clot in Primary Pterygium Surgery Compared With Suture Technique in a Tertiary Hospital of Bangladesh","authors":"Md Iftekher Iqbal, Fariah Osman, Md. Firoz Kabir, S. Parvez","doi":"10.54646/bijcroo.021","DOIUrl":"https://doi.org/10.54646/bijcroo.021","url":null,"abstract":"Purpose: The aim of this study is to assess the efficacy among patients undergoing pterygium excision and conjunctival autograft utilizing autologous blood or sutures. Methods: A randomized controlled trial of 1 year and 5 months, with 60 eyes from 60 patients having primary nasal pterygium. As indicated by inclusion criteria, they were chosen and randomized into two arms for conjunctival autograft: treated arm A (30) with autologous blood and arm B (30) with stitches (10-0 monofilament nylon). Preoperative and postoperative results were assessed and analyzed statistically. Follow-up was done at first, seventh, 1-month, 3-month, and half-year postoperative days. Resulting factors were total surgical time, postoperative comfort, graft stability, and recurrence. Results: 60 patients; mean age of 46.77 ± 7.04 (SD) in arm A (30) and 46.17±7.53 (SD) in arm B (30). In arm A, 22 males (73.3%) and 8 females (26.7%) where arm B had 20 males (66.7%) and 10 females (33.3%). Total surgical time in arm A was 24.73 ± 3.69 (SD) minutes and in arm B was 32.23 ± 4.59 (SD) minutes (p < 0.001). Follow-up at the 1st and 7th POD showed significant discomfort in arm B (mean ranks 41.82 and 40.62) compared to arm A (mean ranks 19.18 and 20.38), respectively (p < 0.001). At 1st POD, only 3 (10%) graft retractions in arm A. Within 6 months of follow-up, all grafts were stable; 1 (3.3%) recurrence and 1 (3.3%) granuloma in arm B only. Conclusion: In primary pterygium surgery, autologous blood showed excellent postoperative results with no recurrence and reduced surgical time. So, it seems to be an effective surgical means to treat primary pterygium.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130941572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Biswas Sujit Kumar, A. S. M. Mahbubul Alam, Ahmed Ria Tanjila, Matin Bhuiyan Abdul
Aim: To describe the temporary management of corneal perforation by using dried sclera patch graft prior keratoplasty when donor tissue not available. Case report: Two cases of corneal perforation (>2mm) of various causes presented with severely decreased vision and shallow anterior chamber and soft eye ball. Both needed immediate therapeutic keratoplasty to save the globe and restore the vision. Due to unavailability of donor cornea, both patients were surgically managed with dried scleral patch graft temporarily to save the globe. Both patients underwent therapeutic keratoplasty one moth and one and half months respectively. Both patients gained better vision (6/18 and 6/24 respectively), quiet anterior chamber and no secondary glucoma after 6 month of keratoplasty. Conclusion: Dried sclera patch graft is a good option for temporary management of corneal perforation of various causes until a donor cornea is available. These patch grafts prevent ocular hypotony, posterior synechiea and secondary glucoma.
{"title":"Dried Scleral Patch Graft: A Temporary Measure of Corneal Perforation Prior Keratoplasty-Two Case Reports","authors":"Biswas Sujit Kumar, A. S. M. Mahbubul Alam, Ahmed Ria Tanjila, Matin Bhuiyan Abdul","doi":"10.54646/bijcroo.013","DOIUrl":"https://doi.org/10.54646/bijcroo.013","url":null,"abstract":"Aim: To describe the temporary management of corneal perforation by using dried sclera patch graft prior keratoplasty when donor tissue not available. Case report: Two cases of corneal perforation (>2mm) of various causes presented with severely decreased vision and shallow anterior chamber and soft eye ball. Both needed immediate therapeutic keratoplasty to save the globe and restore the vision. Due to unavailability of donor cornea, both patients were surgically managed with dried scleral patch graft temporarily to save the globe. Both patients underwent therapeutic keratoplasty one moth and one and half months respectively. Both patients gained better vision (6/18 and 6/24 respectively), quiet anterior chamber and no secondary glucoma after 6 month of keratoplasty. Conclusion: Dried sclera patch graft is a good option for temporary management of corneal perforation of various causes until a donor cornea is available. These patch grafts prevent ocular hypotony, posterior synechiea and secondary glucoma.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124934063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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