{"title":"A snake bite case: The value of timely diagnosis and treatment","authors":"Shimaa M. Motawei","doi":"10.15761/ccsr.1000131","DOIUrl":"https://doi.org/10.15761/ccsr.1000131","url":null,"abstract":"","PeriodicalId":10345,"journal":{"name":"Clinical Case Studies and Reports","volume":"107 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73505520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Murat Muratoglu, C. Kavalci, A. Kayipmaz, C. Akpinar
{"title":"A rare cause of abdominal pain: Renal calix rupture","authors":"Murat Muratoglu, C. Kavalci, A. Kayipmaz, C. Akpinar","doi":"10.15761/ccsr.1000113","DOIUrl":"https://doi.org/10.15761/ccsr.1000113","url":null,"abstract":"","PeriodicalId":10345,"journal":{"name":"Clinical Case Studies and Reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88257470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
6-methoxy-8-[[6-methoxy-8-[[6-methoxy-2-methyl-1-(2methylpropyl)-3,4-dihydro-1h-isoquinolin-7-yl]oxy]-2-methyl-1(2-methylpropyl)-3,4-dihydro-1h-isoquinolin-7-yl]oxy]-2-methyl1-(2-methylpropyl)-3,4-dihydro-1h-isoquinolin-7-ol time-resolved absorption and resonance ft-ir and raman biospectroscopy and density functional theory (dft) investigation of vibronic-mode coupling structure in vibrational spectra analysis
{"title":"6-methoxy-8-[[6-methoxy-8-[[6-methoxy-2-methyl-1-(2-methylpropyl)-3,4-dihydro-1h-isoquinolin-7-yl]oxy]-2-methyl-1-(2-methylpropyl)-3,4-dihydro-1h-isoquinolin-7-yl]oxy]-2-methyl-1-(2-methylpropyl)-3,4-dihydro-1h-isoquinolin-7-ol time-resolved absorption and resonance ft-ir and raman biospectroscopy a","authors":"A. Heidari, J. Esposito, Angela Caissutti","doi":"10.15761/ccsr.1000126","DOIUrl":"https://doi.org/10.15761/ccsr.1000126","url":null,"abstract":"6-methoxy-8-[[6-methoxy-8-[[6-methoxy-2-methyl-1-(2methylpropyl)-3,4-dihydro-1h-isoquinolin-7-yl]oxy]-2-methyl-1(2-methylpropyl)-3,4-dihydro-1h-isoquinolin-7-yl]oxy]-2-methyl1-(2-methylpropyl)-3,4-dihydro-1h-isoquinolin-7-ol time-resolved absorption and resonance ft-ir and raman biospectroscopy and density functional theory (dft) investigation of vibronic-mode coupling structure in vibrational spectra analysis","PeriodicalId":10345,"journal":{"name":"Clinical Case Studies and Reports","volume":"240 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76921594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eduardo an-Zubero, C. García-Muro, M. Alatorre-Jiménez, A. Marín-Medina, C. López-García, A. Youssef, R. Villeda-González
Onset of fast ventricular tachycardia after spontaneous termination of atrial fibrillation is unusual and the mechanism is not well known. There are few case reports in the literatura and the authors did not found the physiopathological points of this entity. Hereby we present a 73-year-old man atrial fibrillation with short periods of non-sustained ventricular tachycardia treated with amiodarone effectively. Coronary angiography, an ergometry as well as an echocardiogram were realized to complete the study showing any disturbs. *Correspondence to: Eduardo Esteban-Zubero, Department of Emergency, Hospital San Pedro, Logroño, Spain, E-mail: eezubero@gmail.com
{"title":"Simultaneous associated onset of atrial fibrillation and ventricular tachycardia without structural cardiopathy - A case report","authors":"Eduardo an-Zubero, C. García-Muro, M. Alatorre-Jiménez, A. Marín-Medina, C. López-García, A. Youssef, R. Villeda-González","doi":"10.15761/ccsr.1000122","DOIUrl":"https://doi.org/10.15761/ccsr.1000122","url":null,"abstract":"Onset of fast ventricular tachycardia after spontaneous termination of atrial fibrillation is unusual and the mechanism is not well known. There are few case reports in the literatura and the authors did not found the physiopathological points of this entity. Hereby we present a 73-year-old man atrial fibrillation with short periods of non-sustained ventricular tachycardia treated with amiodarone effectively. Coronary angiography, an ergometry as well as an echocardiogram were realized to complete the study showing any disturbs. *Correspondence to: Eduardo Esteban-Zubero, Department of Emergency, Hospital San Pedro, Logroño, Spain, E-mail: eezubero@gmail.com","PeriodicalId":10345,"journal":{"name":"Clinical Case Studies and Reports","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77750007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Femoral implant screwed on the lateral femoral shaft","authors":"Y. Cirotteau","doi":"10.15761/ccsr.1000124","DOIUrl":"https://doi.org/10.15761/ccsr.1000124","url":null,"abstract":"","PeriodicalId":10345,"journal":{"name":"Clinical Case Studies and Reports","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77010728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
There was no structural abnormality in echocardiography. But Cardiac catheterization revealed the presence of distal aortic obstruction by a large intraluminal thrombus. An attempt to dissolve the thrombus with urokinase infusion was unsuccessful. The affected vessels were then surgically explored and a large thrombus from the distal abdominal aorta was removed. Following this the child recovered uneventfully with return of lower limb pulsation. A thrombotic profile revealed the underlying diagnosis of congenital Protein C deficiency and a simultaneous thrombophilic prothrombin gene mutation. This is an extremely unusual presentation of neonatal thrombosis treated by successful vascular surgical procedure.
{"title":"Coexistence of protein C deficiency and prothrombin gene mutation causing neonatal thrombosis","authors":"K. Acharyya, S. Acharyya","doi":"10.15761/ccsr.1000121","DOIUrl":"https://doi.org/10.15761/ccsr.1000121","url":null,"abstract":"There was no structural abnormality in echocardiography. But Cardiac catheterization revealed the presence of distal aortic obstruction by a large intraluminal thrombus. An attempt to dissolve the thrombus with urokinase infusion was unsuccessful. The affected vessels were then surgically explored and a large thrombus from the distal abdominal aorta was removed. Following this the child recovered uneventfully with return of lower limb pulsation. A thrombotic profile revealed the underlying diagnosis of congenital Protein C deficiency and a simultaneous thrombophilic prothrombin gene mutation. This is an extremely unusual presentation of neonatal thrombosis treated by successful vascular surgical procedure.","PeriodicalId":10345,"journal":{"name":"Clinical Case Studies and Reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88602408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diphtheria toxin is an exotoxin secreted by Corynebacterium diphtheriae, the pathogenic bacterium that causes diphtheria. Unusually, the toxin gene is encoded by a bacteriophage (a virus that infects bacteria). The toxin causes the disease in humans by gaining entry into the cell cytoplasm and inhibiting protein synthesis. Parameters such as FT -IR and Raman vibrational wavelengths and intensities for single crystal Diphtheria Toxin are calculated using density functional theory and were compared with empirical results. The investigation about vibrational spectrum of cycle dimers in crystal with carboxyl groups from each molecule of acid was shown that it leads to create Hydrogen bonds for adjacent molecules. The current study aimed to investigate the possibility of simulating the empirical values. Analysis of vibrational spectrum of Diphtheria Toxin is performed based on theoretical simulation and FT-IR empirical spectrum and Raman empirical spectrum using density functional theory in levels of HF/6-31G*, HF/6-31++G**, MP2/6-31G, MP2/6-31++G**, BLYP/6-31G, BLYP/6-31++G**, B3LYP/6-31G and B3LYP6-31HEG**. Vibration modes of methylene, carboxyl acid and phenyl cycle are separately investigated. The obtained values confirm high accuracy and validity of results obtained from calculations.
{"title":"Diphtheria toxin time-resolved absorption and resonance ft-ir and raman biospectroscopy and density functional theory (dft) investigation of vibronic-mode coupling structure in vibrational spectra analysis: a spectroscopic study on an anti-cancer drug","authors":"A. Heidari, J. Esposito, Angela Caissutti","doi":"10.15761/ccsr.1000129","DOIUrl":"https://doi.org/10.15761/ccsr.1000129","url":null,"abstract":"Diphtheria toxin is an exotoxin secreted by Corynebacterium diphtheriae, the pathogenic bacterium that causes diphtheria. Unusually, the toxin gene is encoded by a bacteriophage (a virus that infects bacteria). The toxin causes the disease in humans by gaining entry into the cell cytoplasm and inhibiting protein synthesis. Parameters such as FT -IR and Raman vibrational wavelengths and intensities for single crystal Diphtheria Toxin are calculated using density functional theory and were compared with empirical results. The investigation about vibrational spectrum of cycle dimers in crystal with carboxyl groups from each molecule of acid was shown that it leads to create Hydrogen bonds for adjacent molecules. The current study aimed to investigate the possibility of simulating the empirical values. Analysis of vibrational spectrum of Diphtheria Toxin is performed based on theoretical simulation and FT-IR empirical spectrum and Raman empirical spectrum using density functional theory in levels of HF/6-31G*, HF/6-31++G**, MP2/6-31G, MP2/6-31++G**, BLYP/6-31G, BLYP/6-31++G**, B3LYP/6-31G and B3LYP6-31HEG**. Vibration modes of methylene, carboxyl acid and phenyl cycle are separately investigated. The obtained values confirm high accuracy and validity of results obtained from calculations.","PeriodicalId":10345,"journal":{"name":"Clinical Case Studies and Reports","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78384502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Velasco-Álvarez, Javier Pozas Pérez, S. Díaz-Lobato
High Flow Nasal Cannula (HFNC) oxygen therapy is a recent technique that delivers a high flow of heated and humidified gas to the patient.1 Compared to noninvasive ventilation (NIV), HFNC has been proved to be an effective alternative treatment for acute respiratory failure. HFNC also has a significant number of physiological advantages compared with other commonly used oxygen-based therapies, including PEEP, reduced anatomical dead space, constant FiO2 and it is better tolerated than NIV. 2 After a thorough bibliographical research, only one article was found assessing the benefits of using HFNC in patients with acute pulmonary embolism.3 We present the case of an 86-year-old patient with acute pulmonary embolism and desaturation refractory to noninvasive ventilation that was successfully treated with high flow therapy.
{"title":"Satisfactory use of high flow nasal cannula in a patient with acute pulmonary embolism","authors":"D. Velasco-Álvarez, Javier Pozas Pérez, S. Díaz-Lobato","doi":"10.15761/ccsr.1000114","DOIUrl":"https://doi.org/10.15761/ccsr.1000114","url":null,"abstract":"High Flow Nasal Cannula (HFNC) oxygen therapy is a recent technique that delivers a high flow of heated and humidified gas to the patient.1 Compared to noninvasive ventilation (NIV), HFNC has been proved to be an effective alternative treatment for acute respiratory failure. HFNC also has a significant number of physiological advantages compared with other commonly used oxygen-based therapies, including PEEP, reduced anatomical dead space, constant FiO2 and it is better tolerated than NIV. 2 After a thorough bibliographical research, only one article was found assessing the benefits of using HFNC in patients with acute pulmonary embolism.3 We present the case of an 86-year-old patient with acute pulmonary embolism and desaturation refractory to noninvasive ventilation that was successfully treated with high flow therapy.","PeriodicalId":10345,"journal":{"name":"Clinical Case Studies and Reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84905495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: Genetic instability is one of the basic reasons for the survival. In this study, a very high genetic imbalance that is inconsistent with cough and life can not be explained with our current genetic information. Materials and methods: We performed cytogenetic analysis by G-banding in an adult girl, aged 23 years, with hundreds of chromosomal abnormalities (CAs). While she has been evaluating for diffuse parenchymal lung disease (DPLD), was considered to have a possible genetic disorder. Results: We observed that there was at least one or more structural and/or numerical CAs in a cell of a person. The numerical and structural aberrations were found in 94.3% of cells analyzed. These CAs were a very serious and very important genetic instability. However, these hundreds of CAs had reflected to clinic appearence with the symptom of dyspnea, cough for the last 5 months, atypical facial and growth retardation. Conclusion: There is a relationship between chromosome damage and symptoms of dyspnea, cough. We are in an inappropriate situation with normal mitosis. It needs to be investigated and explained. *Correspondence to: Osman Demirhan, Department of Medical Biology and Genetics, Faculty of Medicine, Çukurova University, 01330 Balcalı-Adana, Turkey, Tel: 903223387140, Fax: 90-322-3386572, E-mail: osdemir@cu.edu.tr
{"title":"Relationship between symptoms of dyspnea, cough and chromosomal imbalance","authors":"O. Demirhan, S. Kuleci, Oya Baydar","doi":"10.15761/ccsr.1000119","DOIUrl":"https://doi.org/10.15761/ccsr.1000119","url":null,"abstract":"Objectives: Genetic instability is one of the basic reasons for the survival. In this study, a very high genetic imbalance that is inconsistent with cough and life can not be explained with our current genetic information. Materials and methods: We performed cytogenetic analysis by G-banding in an adult girl, aged 23 years, with hundreds of chromosomal abnormalities (CAs). While she has been evaluating for diffuse parenchymal lung disease (DPLD), was considered to have a possible genetic disorder. Results: We observed that there was at least one or more structural and/or numerical CAs in a cell of a person. The numerical and structural aberrations were found in 94.3% of cells analyzed. These CAs were a very serious and very important genetic instability. However, these hundreds of CAs had reflected to clinic appearence with the symptom of dyspnea, cough for the last 5 months, atypical facial and growth retardation. Conclusion: There is a relationship between chromosome damage and symptoms of dyspnea, cough. We are in an inappropriate situation with normal mitosis. It needs to be investigated and explained. *Correspondence to: Osman Demirhan, Department of Medical Biology and Genetics, Faculty of Medicine, Çukurova University, 01330 Balcalı-Adana, Turkey, Tel: 903223387140, Fax: 90-322-3386572, E-mail: osdemir@cu.edu.tr","PeriodicalId":10345,"journal":{"name":"Clinical Case Studies and Reports","volume":"144 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77457439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Received: June 04, 2019; Accepted: July 03, 2019; Published: July 10, 2019 DNA/RNA hypermethylation and hypomethylation is hygroscope and can be mixed easily with human cancer cells, tissues and tumors and lots of organic components. Hydrate inhabitation, coolant, stabilizer, etc. are some applications of DNA/RNA hypermethylation and hypomethylation. DNA/RNA hypermethylation and hypomethylation are used widely in human cancer cells, tissues and tumors extraction sites as an anti–freezing substance. Therefore, it’s found in the effluent of human cancer cells, tissues and tumors refinery science. Besides, DNA/ RNA hypermethylation and hypomethylation are traced in the effluent of DNA/RNA hypermethylation and hypomethylation producing science. According to presence of DNA/RNA hypermethylation and hypomethylation in the monitoring of human cancer cells, tissues and tumors, the effect of presence of DNA/RNA hypermethylation and hypomethylation on a moving synchrotron radiation and synchrocyclotron radiation performance is investigated in this research. The experiments where designed for 200, 400, 600, 800 and 1000 (ppm) of DNA/RNA hypermethylated and hypomethylated’s concentrations. The hydraulic retention time was set 96 hours for the of synchrotron radiation and 48 hours for the synchrocyclotron radiation. The DNA/ RNA hypermethylated and hypomethylated removal percentage for the synchrotron radiation was measured 27.3%, 46.9% and 71.7% for different concentrations, respectively. This parameter was measured for the second system 54.6%, 68.3% and 79.4%, respectively. The study was carried out using synchrotron radiation and synchrocyclotron radiation performance in monitoring of human cancer cells, tissues and tumors, plus balanced macro nutrients and alkalinity. The DNA/RNA hypermethylated and hypomethylated was enriched with the macronutrients by adding some proteins as Nitrogen sources and nucleic acids as Phosphorus sources and in addition to different amount of DNA/RNA hypermethylated and hypomethylated concentration from 500 to 700 (ppm). The temperature and pH of the influent were set as 23 ± 3 C° and 7.0 ± 7, respectively (Figure 1) [1-364].
{"title":"Comparison of synchrotron radiation and synchrocyclotron radiation performance in monitoring of human cancer cells, tissues and tumors","authors":"A. Heidari","doi":"10.15761/ccsr.1000127","DOIUrl":"https://doi.org/10.15761/ccsr.1000127","url":null,"abstract":"Received: June 04, 2019; Accepted: July 03, 2019; Published: July 10, 2019 DNA/RNA hypermethylation and hypomethylation is hygroscope and can be mixed easily with human cancer cells, tissues and tumors and lots of organic components. Hydrate inhabitation, coolant, stabilizer, etc. are some applications of DNA/RNA hypermethylation and hypomethylation. DNA/RNA hypermethylation and hypomethylation are used widely in human cancer cells, tissues and tumors extraction sites as an anti–freezing substance. Therefore, it’s found in the effluent of human cancer cells, tissues and tumors refinery science. Besides, DNA/ RNA hypermethylation and hypomethylation are traced in the effluent of DNA/RNA hypermethylation and hypomethylation producing science. According to presence of DNA/RNA hypermethylation and hypomethylation in the monitoring of human cancer cells, tissues and tumors, the effect of presence of DNA/RNA hypermethylation and hypomethylation on a moving synchrotron radiation and synchrocyclotron radiation performance is investigated in this research. The experiments where designed for 200, 400, 600, 800 and 1000 (ppm) of DNA/RNA hypermethylated and hypomethylated’s concentrations. The hydraulic retention time was set 96 hours for the of synchrotron radiation and 48 hours for the synchrocyclotron radiation. The DNA/ RNA hypermethylated and hypomethylated removal percentage for the synchrotron radiation was measured 27.3%, 46.9% and 71.7% for different concentrations, respectively. This parameter was measured for the second system 54.6%, 68.3% and 79.4%, respectively. The study was carried out using synchrotron radiation and synchrocyclotron radiation performance in monitoring of human cancer cells, tissues and tumors, plus balanced macro nutrients and alkalinity. The DNA/RNA hypermethylated and hypomethylated was enriched with the macronutrients by adding some proteins as Nitrogen sources and nucleic acids as Phosphorus sources and in addition to different amount of DNA/RNA hypermethylated and hypomethylated concentration from 500 to 700 (ppm). The temperature and pH of the influent were set as 23 ± 3 C° and 7.0 ± 7, respectively (Figure 1) [1-364].","PeriodicalId":10345,"journal":{"name":"Clinical Case Studies and Reports","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73710873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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