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Permanent Pacemaker Implantation Challenged by an Elevated Left Hemidiaphragm 永久性心脏起搏器植入受到左膈升高的挑战
Pub Date : 2021-02-20 DOI: 10.31579/2690-8794/055
Farla Louis
This is a case of a 93 year old patient who presented with a syncopal episode due to infra-nodal atrio-ventricular block (AVB) which required placement of a permanent pacemaker (PPM). The initial pre-procedure chest x-ray (CXR) showed an elevated left hemidiaphragm with shifting of the heart to the right making PPM implant challenging.
这是一个93岁的病人,由于结下房室传导阻滞(AVB)而出现晕厥发作,需要放置永久性起搏器(PPM)。最初的术前胸部x光片(CXR)显示左膈升高,心脏向右移动,使PPM植入具有挑战性。
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引用次数: 0
Influence of Determinants of Diabetes on Sexual Quality using Discriminant Functions 用判别函数分析糖尿病决定因素对性质量的影响
Pub Date : 2021-01-01 DOI: 10.31579/2690-8794/063
A. Alhassan
This paper seeks to give a better understanding of the influence of age, creatinine level, duration of diabetes, glucose level and pulse rate on diabetic-induced sexual dysfunction among people. The study employed two-way MANOVA with balanced samples of 115 each. Prior to the analysis, univariate and multivariate normality, linearity, equality of error and covariance matrices, and multicollinearity assumptions were satisfied. Significance was attained for both sex and marital status (P < 0.05), though their interaction effect was not significant (P > 0.05). Wald’s test for individual groups confirmed the hypothetical decision of MANOVA, though independent T2 failed to report significance for marital status. Under the parameter estimation, it was ascertained that the difference between the groups was in terms of age and creatinine levels of people. The model is also considered credible since bootstrap estimates converged to the empirical estimates. Even though this paper did not exhaust all metabolic and comorbid factors relating to diabetes, it is hoped that it provides an insight into some circumstances in the evolution of diabetes.
本文旨在更好地了解年龄、肌酐水平、糖尿病病程、血糖水平和脉搏率对糖尿病性性功能障碍的影响。本研究采用双向方差分析,平衡样本各为115个。在分析之前,满足单变量和多变量正态性、线性、误差相等和协方差矩阵以及多重共线性假设。性别和婚姻状况的交互作用不显著(P > 0.05),但差异均有统计学意义(P < 0.05)。Wald对个体群体的检验证实了方差分析的假设结论,尽管独立T2未能报告婚姻状况的显著性。在参数估计下,确定各组之间的差异是在年龄和人的肌酐水平方面。该模型也被认为是可信的,因为自举估计收敛于经验估计。尽管本文没有穷尽与糖尿病相关的所有代谢和合并症因素,但希望它能对糖尿病演变的某些情况提供一个深入的了解。
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引用次数: 0
Spontaneous Drainage of Large Parapharyngeal Abscess 咽旁大脓肿的自然引流
Pub Date : 2021-01-01 DOI: 10.31579/2690-8794/081
Camilla Melotti Berkembrock
The case of a 68-year-old female patient, without comorbidities, with a diagnosis of a large parapharyngeal abscess on the left, was reported by a neck CT scan, which evolved with spontaneous drainage and complete resolution of the peritonsillar bulging, completing the therapeutic plan with antibiotic therapy, without abscess recurrence. Clinical suspicion, associated with neck CT, is an indispensable item in the design of early treatment, in order to avoid complications.
68岁女性患者,无合并症,颈部CT扫描诊断为左侧咽旁大脓肿,自发性引流,囊周肿胀完全消退,抗生素治疗完成,无脓肿复发。临床怀疑,结合颈部CT,是早期治疗设计中不可缺少的项目,以避免并发症。
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引用次数: 0
A Case Report of Atypical Hyponatremia Caused by Diarrhea Following a Course of Ferrous Sulfate Supplements 补充硫酸亚铁一疗程后腹泻所致非典型低钠血症1例
Pub Date : 2021-01-01 DOI: 10.31579/2690-8794/058
L. Ranasinghe
Hyponatremia, defined as a serum sodium level less than 135 mg/mL, can be euvolemic, hypovolemic, or hypervolemic. Its presentation can be subtle or severe depending on whether the hyponatremia is acute or chronic. This case investigates a geriatric patient who suffered diarrhea and hyponatremia following a course of ferrous sulfate pills for anemia treatment. Given that ferrous sulfate pills usually result in constipation, this presentation was abnormal. Literature review and comparison to prior atypical situations resulted in the conclusion that the patient’s diarrhea was likely a result of her Crohn’s diagnosis. The subsequent resulting hyponatremia was likely due to this diarrhea coupled with her prescription thiazide diuretic which can cause hyponatremia as a common side effect. This report allows for physicians to understand potential causes behind atypical electrolyte abnormalities in their patients and hence, find an effective treatment plan.
低钠血症定义为血清钠水平低于135mg /mL,可表现为低血容量血症、低血容量血症或高血容量血症。它的表现可以是轻微的或严重的取决于低钠血症是急性还是慢性。本病例调查了一位老年患者,他在服用硫酸亚铁丸治疗贫血后出现腹泻和低钠血症。鉴于硫酸亚铁丸通常导致便秘,这种表现是不正常的。文献回顾和比较以往的非典型情况导致的结论是,病人的腹泻可能是她的克罗恩病的诊断结果。随后的低钠血症可能是由于腹泻加上她的处方噻嗪利尿剂,可引起低钠血症作为一个常见的副作用。该报告使医生能够了解患者非典型电解质异常背后的潜在原因,从而找到有效的治疗方案。
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引用次数: 0
The smoking economic burden by morbidity 吸烟造成的经济负担
Pub Date : 2020-12-26 DOI: 10.31579/2690-8794/051
F. Hernández
Background: The research and analysis from smoking must be from several points of view. Nevertheless the smoking economic burden by morbidity must be strongly researched since the Health Economy. The usefulness from postgraduate course about this subject offer the opportunity to generalize the whole knowledge obtained. Thus more health professional will be better capacitated to make better measures from the smoking economic impact over the Public Health. Objective: To design a postgraduate trainer course about the measurement from the smoking economic burden by morbidity. Materials and methods: Were used the inductive – deductive and the comparative as theoretical methods. As empiric method was used the bibliographic research. Results: The suggested course has the particularity of be contextualized agree to general learning needs from health professionals related to the smoking economic control. The course has the characteristic that each subject is supported by the previous. Conclusion: Was designed a postgraduate trainer course for health professionals related with the smoking economic control. The course is agreed to general learning needs from health professionals related to the smoking economic control.
背景:对吸烟的研究和分析必须从几个角度出发。然而,从健康经济的角度来看,必须对吸烟造成的经济负担进行强有力的研究。研究生课程关于这一主题的有用性提供了推广所获得的全部知识的机会。因此,更多的卫生专业人员将更有能力从吸烟对公共卫生的经济影响中做出更好的措施。目的:设计从发病率角度衡量吸烟经济负担的研究生培训课程。材料和方法:采用归纳演绎法和比较法作为理论方法。文献研究采用实证方法。结果:建议的课程具有情境化的特殊性,符合卫生专业人员对吸烟经济控制的一般学习需求。本课程的特点是各科互为依托。结论:为与吸烟经济控制有关的卫生专业人员设计了研究生培训课程。本课程是针对与吸烟经济管制有关的卫生专业人员的一般学习需要而开设的。
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引用次数: 2
Rendezvous for afferent limb syndrome 输入肢体综合症的集合点
Pub Date : 2020-12-26 DOI: 10.31579/2690-8794/049
Ivan Mendez
Endoscopic retrograde cholangiopancreatography (ERCP) in patients with surgical alterations in the normal biliary anatomy is technically challenging. We describe the case of a 73-year-old patient with an afferent limb syndrome secondary to a Whipple procedure for pancreatic cancer, in which a percutaneous rendezvous technique assisted in the endoscopic metallic stent placement with favorable outcome.
内镜逆行胆管造影(ERCP)在手术改变正常胆道解剖结构的患者中具有技术挑战性。我们描述了一个73岁的患者的病例传入肢体综合征继发于胰腺癌惠普尔手术,其中经皮会合技术协助在内镜下金属支架放置良好的结果。
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引用次数: 0
We need to Overpopulate Bats not Birds for Prevention of Covid 19 totally 为了完全预防Covid - 19,我们需要过度繁殖蝙蝠,而不是鸟类
Pub Date : 2020-12-26 DOI: 10.31579/2690-8794/054
C. Koyunoğlu
Mink's role in nature is important. Since mink is a carnivorous species, there are small mammals such as crayfish, snakes, turtles, small birds, mice, rabbits, insects, and crustaceans in the food chain. The most important of the practices that threaten the life of the mink is the cutting of the trees where the mink lives for furniture or energy production. Another threat is that their fur is made into clothes, as in Denmark, where 1 billion dollars of exports are made annually. However, the recent acceptance of the covid virus as a host to humans resulted in 17 million minks being buried in the mass grave in just the first week, and then the entire culling of them. Here it is not the resignation of a responsible prime minister. It is the threat that the mink, which forms part of the food chain, will suddenly increase the population of small birds, which play a key role in world food production. Of course, the purpose here is not to blame everyone unconsciously. However, instead of interfering with the chain in nature, the mink should be kept under quarantine by considering the antibody formed in the bodies of the mink as a treatment tool. Now the world should be prepared for unexpected adverse effects, such as the growing bird population with the disappearance of those 17 million minks. The species that need to be increased in the fight against Covid-19 are bats, the main source of the virus. Because bats may have carried a combination of SARS and MERS viruses from the same source in the past as a defense mechanism to adapt to nature with the depletion of water flies in the world with the restriction of water resources. The presence of any population in nature that is more than normal may further limit the use of a biosource present in nature. Every intervention in nature inevitably confronts humanity. As an alternative thought, it may be suggested that minks should not be considered as a commercial purpose in human life or should be restricted.
水貂在自然界中的作用很重要。由于水貂是一种食肉动物,因此在食物链中有小龙虾、蛇、乌龟、小鸟、老鼠、兔子、昆虫和甲壳类动物等小型哺乳动物。在威胁水貂生存的行为中,最重要的是为了家具或能源生产而砍伐水貂生活的树木。另一个威胁是,它们的皮毛被制成衣服,就像丹麦一样,那里每年的出口额达到10亿美元。然而,最近人们承认新冠病毒是人类的宿主,这导致1700万只水貂在第一周被埋在万人坑里,然后被全部扑杀。这不是一位负责任的首相的辞职。它的威胁是,作为食物链一部分的水貂会突然增加小鸟的数量,而小鸟在世界粮食生产中起着关键作用。当然,这里的目的并不是不自觉地责怪每个人。但是,与其自然地干扰这条链,不如考虑到水貂体内形成的抗体作为治疗工具,对水貂进行隔离。现在,世界应该为意想不到的负面影响做好准备,比如1700万只水貂的消失会导致鸟类数量的增加。在抗击Covid-19的斗争中需要增加的物种是蝙蝠,蝙蝠是病毒的主要来源。因为蝙蝠可能在过去携带了来自同一来源的SARS和MERS病毒的组合,作为一种适应自然的防御机制,随着世界上水蝇的枯竭,水资源的限制。自然界中存在的任何种群超过正常水平,都可能进一步限制对自然界中存在的生物源的使用。对自然的任何干预都不可避免地要面对人类。作为另一种想法,有人可能会建议,水貂不应该被视为人类生活中的商业目的,或者应该受到限制。
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引用次数: 0
Recurrent Syncope in a patient with Sleep Apnea and Narcolepsy resolved after Permanent Pacemaker Implant 永久性起搏器植入后,睡眠呼吸暂停和发作性睡患者复发性晕厥缓解
Pub Date : 2020-11-16 DOI: 10.31579/2690-8794/027
Farla Jean-Louis, G. Upadhya, Asma Syed
Concomitant narcolepsy and sleep apnea (SA) can be present in the same patient. We present a patient with recurrent episodes of syncope and subsequent falls, which were found to be due to narcolepsy and Obstructive Sleep Apnea (OSA). She was initially treated with continuous positive airway pressure (CPAP) but continued to have symptoms sustaining injury. Her symptoms resolved with placement of a permanent pacemaker (PPM) implant and to date has not had any recurrence.
发作性睡病和睡眠呼吸暂停(SA)可同时出现在同一患者身上。我们报告一个反复发作晕厥和随后跌倒的病人,这是由于发作性睡病和阻塞性睡眠呼吸暂停(OSA)。她最初接受持续气道正压通气(CPAP)治疗,但仍有持续损伤的症状。她的症状在植入永久起搏器(PPM)后得到缓解,迄今为止没有任何复发。
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引用次数: 0
A prescription for improvement: Health and Safety Measures 改善的处方:健康和安全措施
Pub Date : 2020-11-16 DOI: 10.15520/jmrhs.v2i4.41
A. Omer
The strategy of price liberalization and privatization had been implemented in Sudan over the last decade, and has had a positive result on government deficit. The investment law approved recently has good statements and rules on the above strategy in particular to pharmacy regulations. Under the pressure of the new privatization policy, the government introduced radical changes in the pharmacy regulations. To improve the effectiveness of the public pharmacy, resources should be switched towards areas of need, reducing inequalities and promoting better health conditions. Medicines are financed either through cost sharing or full private. The role of the private services is significant. A review of reform of financing medicines in Sudan is given in this study. Also, it highlights the current drug supply system in the public sector, which is currently responsibility of the Central Medical Supplies Public Corporation (CMS). In Sudan, the researchers did not identify any rigorous evaluations or quantitative studies about the impact of drug regulations on the quality of medicines and how to protect public health against counterfeit or low quality medicines, although it is practically possible. However, the regulations must be continually evaluated to ensure the public health is protected against by marketing high quality medicines rather than commercial interests, and the drug companies are held accountable for their conduct.
过去十年来,苏丹实施了价格自由化和私有化战略,并对政府赤字产生了积极的影响。最近批准的投资法对上述战略有很好的表述和规定,特别是对药品的规定。在新的私有化政策的压力下,政府对药房的规定进行了彻底的改革。为了提高公共药房的效力,应将资源转向需要的领域,减少不平等现象,促进改善保健条件。药品的资金要么通过费用分摊,要么完全由私人提供。私营部门的作用是重要的。本研究对苏丹药品融资改革进行了回顾。此外,它还强调了目前由中央医疗用品公共公司(CMS)负责的公共部门药品供应系统。在苏丹,这组科学家没有发现关于药品管制对药品质量的影响以及如何保护公众健康免受假药或低质量药品影响的任何严格评估或定量研究,尽管这实际上是可能的。然而,必须不断对这些条例进行评估,以确保公众健康不受销售高质量药品而不是商业利益的影响,并确保制药公司对其行为负责。
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引用次数: 0
Performance of the Boditech iCHROMA Covid-19 IgG antibody assay with the external quality control for UK NIBSC (National Institute of Biological Standards and Control) 英国国家生物标准与控制研究所(NIBSC) Boditech iCHROMA Covid-19 IgG抗体检测的外部质量控制性能
Pub Date : 2020-11-16 DOI: 10.31579/2690-8794/048
J. B. Bolodeoku
Background: There is a need for laboratories to participate in EQA schemes to achieve a harmonization of test results and to improve serological testing and research on COVID-19 and SARS-CoV-2. The Boditech iCHROMA point of care immunoassay analyser has a Covid-19 antibody assay for the qualitative determination of IgG antibodies in human whole blood/serum/plasma. The National Institute for Biological Standards and Control (NIBSC) in the United Kingdom has a portfolio of reference and research reagents, including reagents for EQA that are available to laboratories to help them set up and develop accurate diagnostic tests for SARS-CoV-2 assays. Objectives: To determine the performance of the Boditech iCHROMA Covid-19 IgG antibody assay using the external quality control material provided by the UK NIBSC (National Institute for Biological Standards and Control). Results: The Boditech iCHROMA Covid-19 IgG assay using the cut off index >1.1, reported the results of the 33 positive control samples as positive with index range from 19.50 – 29.00, with a mean of 23.75 and standard deviation of SD of 2.53. It also reported the results of the 33 negative control samples as negative with an index range of 0.00 for all samples. Conclusion: The performance of the Boditech iCHROMA Covid-19 IgG antibody assay using external quality control material from the UK NIBSC was very good, confirming the precision of the Boditech iCHROMA Covid 19 IgG antibody method.
背景:实验室有必要参与EQA计划,以实现检测结果的统一,并改进COVID-19和SARS-CoV-2的血清学检测和研究。Boditech iCHROMA护理点免疫测定分析仪具有Covid-19抗体测定,可定性测定人全血/血清/血浆中的IgG抗体。英国国家生物标准和控制研究所(NIBSC)拥有一系列参考和研究试剂,包括EQA试剂,可供实验室使用,帮助它们建立和开发用于SARS-CoV-2测定的准确诊断测试。目的:利用英国国家生物标准与控制研究所(NIBSC)提供的外部质量控制材料,确定Boditech iCHROMA新冠病毒IgG抗体检测的性能。结果:Boditech iCHROMA Covid-19 IgG检测在切断指数>1.1的情况下,33份阳性对照样品的检测结果为阳性,切断指数范围为19.50 ~ 29.00,平均值为23.75,标准差为2.53。报告了33个阴性对照样本的结果为阴性,所有样本的指数范围为0.00。结论:采用来自英国NIBSC的外部质控材料,Boditech iCHROMA Covid-19 IgG抗体检测效果良好,证实了Boditech iCHROMA Covid-19 IgG抗体检测方法的准确性。
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引用次数: 0
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Clinical Medical Reviews and Reports
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