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Dermatofibroma Frequent Disease, Uncommon Location 皮肤纤维瘤多发病,部位不常见
Pub Date : 2020-02-14 DOI: 10.31579/2690-8794/003
R. Chaoui
Dermatofibroma (DF) is a very common benign tumor, which occurs most often in middle-aged women. In general, DF presents as a solitary lesion on the extremities, shoulders or buttock, which occasionally develops following minor trauma or an insect bite. We describe a case of dermatofibroma involving the dorsum of right hand.
皮肤纤维瘤(DF)是一种非常常见的良性肿瘤,多见于中年妇女。一般来说,DF表现为四肢、肩部或臀部的孤立病变,偶尔在轻微创伤或昆虫叮咬后发展。我们报告一例皮肤纤维瘤累及右手背。
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引用次数: 0
Prevention of Reflux Disease After Operations On Gastric And Intestinal Tract 胃肠道手术后反流性疾病的预防
Pub Date : 2020-02-14 DOI: 10.31579/2690-8794/005
M. V.L.
Creating anastomoses between the hollow organs of the abdominal cavity, abdominal formations of the retroperitoneal space and the jejunum always raises the question of preventing reflux from the jejunum into the drained cavity of the esophagus, stomach, gallbladder, external hepatic ducts, cysts of the liver and pancreas. After surgery, any reflux becomes pathological. Reflux is an obligate precancer. Thus, the reflux of bile and pancreatic juices in the stomach, the stump of the stomach and esophagus contributes to the occurrence of reflux esophagitis, reflux gastritis, ulcers and gastric cancer or its stump. After internal drainage of the cavity formation in the jejunum, postoperative reflux disease develops, which is caused by the actions of the surgeon who tried to help the patient sincerely. This allowed such states to be defined as “iatrogenic postoperative reflux disease”. The purpose of this work was to develop and introduce into practice the “plug” on the resulting loop of the jejunum, which does not migrate into the lumen of the intestine, with internal drainage of the hollow organs of the abdominal cavity and abdominal formations of the retroperitoneal space and evaluate the clinical results. As a result, the authors have developed a method for creating a “plug” on the jejunum loop, which is used for drainage, studies are being conducted on its safety, adequacy of functioning, general accessibility, and clinical situations are analyzed. For drainage of the abdominal formation impose a fistula between it and the jejunum loop 40–50 cm from the ligament of Treitz. We form an inter-intestinal fistula according to Brown, above which the length leading to a drained formation of the area of ​​the jejunum is about 10 cm, in the middle of which we impose a “plug”. The length of the small intestine section which diverts from the drained formation to the inter-intestinal brown anastomosis is about 30 cm. To form a “plug”, we use the free area of ​​the greater omentum, through which we perform a ligature of non-absorbable polypropylene material by vcol-vykola. The developed method of forming a "plug" does not cause abrupt ischemic changes in the area of ​​operation, followed by necrosis of the intestinal wall and migration of the "plug" into the intestinal lumen, and its effectiveness has been proven using clinical observations, microcirculation studies, water test results and X-ray examination. The method of creating a "stub" is promising for the internal drainage of abdominal cavity formations and retroperitoneal space, for the formation of areflux nutrient eunostoma.
在腹腔的中空器官、腹膜后间隙的腹部构造和空肠之间建立吻合口总是提出一个问题,即防止空肠反流进入食管、胃、胆囊、肝外管、肝囊肿和胰腺的排水腔。手术后,任何反流都是病理性的。反流是专性癌前病变。因此,胆汁和胰液在胃、胃残端和食道的反流有助于反流性食管炎、反流性胃炎、溃疡和胃癌或其残端的发生。在空肠形成的空腔内部引流后,发生术后反流性疾病,这是由于外科医生试图真诚地帮助患者的行为引起的。这使得这种状态被定义为“医源性术后反流病”。这项工作的目的是发展和实践“塞”产生的空肠回路,它不会迁移到肠腔,腹腔中空器官的内部引流和腹膜后空间的腹腔形成,并评估临床结果。因此,作者开发了一种在空肠袢上制造“塞”的方法,用于引流,正在对其安全性,功能充分性,一般可及性进行研究,并对临床情况进行分析。在距Treitz韧带40-50厘米处,在其与空肠袢之间建立瘘管以引流腹腔形成物。根据布朗的说法,我们形成一个肠内瘘,其长度超过10厘米,导致空肠区域的排水形成,在中间我们施加一个“塞”。小肠段由引流形成转向肠间棕色吻合的长度约为30 cm。为了形成一个“塞”,我们使用大网膜的自由区域,通过它,我们使用vcolvykola将不可吸收的聚丙烯材料结扎。所开发的形成“塞”的方法不会引起手术区域突然缺血改变,随后肠壁坏死,“塞”向肠腔内移动,其有效性已通过临床观察、微循环研究、水试验结果和x线检查得到证实。制造“短段”的方法有望用于腹腔形成和腹膜后间隙的内引流,用于形成回流营养物真口瘤。
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引用次数: 0
Pulselessness in an HIV Infected adult Female: A Rare Case of Ergotism 一例感染HIV的成年女性无脉搏:麦角症的罕见病例
Pub Date : 2020-02-14 DOI: 10.31579/2690-8794/007
T. Shogade
Ergotism can present with vascular, neurologic and gastrointestinal symptoms including gangrene in severe cases. In HIV, toxicity from interaction with protease inhibitors has been documented. We report case of a female who took cafergot for migraine resulting in absent peripheral pulses. She made a good recovery with steroids and pentoxyfilline
麦角病可表现为血管、神经和胃肠道症状,严重者可出现坏疽。在HIV中,与蛋白酶抑制剂相互作用的毒性已被证实。我们报告的情况下,女性谁服用咖啡因偏头痛导致缺席外周脉搏。她用类固醇和己酮菲林恢复得很好
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引用次数: 0
COVID-19 and Nervous System: underestimated clinical and prognostic aspects
Pub Date : 2020-01-01 DOI: 10.31579/2690-8794/023
I. Filho
The coronavirus pandemic transformed the world abruptly due to the speed of transmission and high morbidity and mortality. Many deaths have been quantified, and the scientific community intensifies the search for molecular targets, protein sequences and polymorphisms on SARS-CoV-2, to improve the clinical evolution and survival of patients. Initially, COVID-19 was described with respiratory changes, flu, and fever. With the spread of the disease, clinical manifestations were observed in other organ systems, still unknown. In this sense, the present study describes the main neurological changes and laboratory findings. The literature review was identified in the central databases: Scielo, Google Scholar, PubMed / MedLine, Embase, and Cochrane Database. Twenty-five articles related to the theme were chosen, including reviews, case series, cohort, and retrospective studies. Neurological manifestations were predominantly anosmia/hyposmia, dysgeusia, ataxia, and seizures. According to the latest published studies, attention must be paid to isolated initial neurological events.
由于传播速度快、发病率和死亡率高,冠状病毒大流行突然改变了世界。许多死亡病例已被量化,科学界加强了对SARS-CoV-2分子靶点、蛋白质序列和多态性的研究,以改善患者的临床进化和生存。最初,COVID-19被描述为呼吸系统变化、流感和发烧。随着疾病的扩散,在其他器官系统是否有临床表现尚不清楚。在这个意义上,本研究描述了主要的神经学变化和实验室结果。文献综述在中央数据库:Scielo,谷歌Scholar, PubMed / MedLine, Embase和Cochrane数据库中进行鉴定。选择了25篇与该主题相关的文章,包括综述、病例系列、队列和回顾性研究。神经学表现主要为嗅觉缺失、语言障碍、共济失调和癫痫发作。根据最新发表的研究,必须注意孤立的初始神经事件。
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引用次数: 0
Non-surgical Removal of Basal Cell Carcinoma by Apis Mellifera L Venom 蜜蜂毒液非手术切除基底细胞癌
Pub Date : 2020-01-01 DOI: 10.31579/2690-8794/056
S. Kamal
Background: Honeybee’s venom is potent anticancer drug without exhibiting any side effects. Skin Basal Cell Carcinoma (SBCC) is a common malignancy. It can cause significant local destructions depending on affected site. The diagnosis of SBCC can be suspected from clinical findings and confirmation of diagnosis histopathology. The present SBCC is recurrent and aggressive in the skin of head [upper right, in front of the right ear]; the patient was 65 years old in time of first intervention. Materials & Methods: Following the lesions primarily surgically excised, the malignant growths recurrent and visual recognition occurred after 1 year from first operation, then another (the second) surgical removal of SBCC from affected skin with removal of all skin layers near the affected site but another recurrence visually occurs after about 4 months, in the form of malignant growth in the skin of right ear. Dry honeybee’s venom 1 mg was dissolved in 1 ml dist. water as injectable solution. Moreover, ointment contains 2% bee venom was prepared to be used topically inside affected ear as injection is not possible. Results: Before this novel intervention, the desperate patient situation seems very dangerous; as the new growths appear as continuous spread near the removed skin, so that patient’s family decided to apply more noninvasive and non-surgical intervention. The only precaution was testing the patients to assure she is not hypersensitive to honeybees’ venom. The treatment performed by subcutaneous injection of 0.3 ml from prepared Honeybees venom (0.1 % conc.) in the skin of affected part of the ear. Subcutaneous infiltration was applied around the lesions of about 0.5 ml as well, topical application of the ointment inside inner part of affected ear. This process repeated daily with cleaning of the ear every time by suitable safe and sterile saline solutions. Management of healing process was enhanced by ascorbic acid solution as topical application on dead cancer cells and to help in exudates debris removal. The complete removal of malignant growths and recovery obtained after 1 month from first bee venom injections. No recurrence of SBCC seen for 3 yrs. Conclusions: Honeybees venom is highly effective and safe anticancer drug that can be used for all patients’ categories of all ages. Regarding the present case invasive surgical intervention was not the good choice from the beginnings, as recurrence and giving chance for spreading following the time lapse between every surgery.
背景:蜂毒是一种有效的抗癌药物,没有任何副作用。皮肤基底细胞癌是一种常见的恶性肿瘤。根据受影响的地点,它可能造成严重的局部破坏。小鳞癌的诊断可以从临床表现和组织病理学诊断的证实中怀疑。目前的SBCC在头部皮肤(右上,右耳前)反复发作,具有侵袭性;首次干预时患者年龄为65岁。材料与方法:在病变主要手术切除后,恶性肿瘤复发并在第一次手术后1年后出现视觉识别,然后另一次(第二次)手术切除受影响皮肤的SBCC,切除受影响部位附近的所有皮肤层,但大约4个月后再次出现视觉复发,以右耳皮肤恶性生长的形式出现。将干蜂毒1毫克溶于1毫升清水中作为注射溶液。此外,药膏含有2%的蜂毒是准备局部使用在受影响的耳朵,因为注射是不可能的。结果:在这种新的干预措施之前,绝望的病人情况似乎很危险;由于新的肿瘤在被切除的皮肤附近持续扩散,因此患者家属决定采用更多的非侵入性和非手术干预。唯一的预防措施是对病人进行测试,以确保她对蜜蜂的毒液没有过敏。将配制好的蜂毒(0.1% conc.)皮下注射0.3 ml于受影响的耳部皮肤。病灶周围皮下浸润约0.5 ml,局部涂抹于患耳内侧。这个过程每天重复,每次用合适的安全和无菌的生理盐水溶液清洁耳朵。治疗过程的管理被增强抗坏血酸溶液局部应用于死亡的癌细胞,并有助于清除渗出物碎片。第一次蜂毒注射后1个月恶性肿瘤完全切除和恢复。3年未见SBCC复发。结论:蜂毒是一种高效、安全的抗癌药物,适用于所有年龄、所有类别的患者。对于本病例,侵入性手术干预从一开始就不是一个好的选择,因为每次手术之间的时间间隔会导致复发和扩散。
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引用次数: 0
Reno Cardiologist Confirms FMTVDM – Opening New Opportunities for Nuclear Cardiologists Reno心脏病专家确认FMTVDM -为核心脏病专家开辟了新的机会
Pub Date : 2019-12-19 DOI: 10.31579/2690-8794/001
R. Fleming
Background: A quantitative myocardial perfusion imaging (MPI) and oncologic - including molecular breast imaging (MBI) - utility patent (FMTVDM*) previously validated at experienced MPI and MBI centers was independently tested for clinical application at a private practice Reno, Nevada cardiologists office. Methods: Using FMTVDM, a private practice cardiologist independently investigated forty-four regions of interest (ROI) in 12-women with varying transitional levels of breast changes – including breast cancer. Results: Using FMTVDM, a nuclear cardiologist without prior experience in MBI was able to easily measure changes in women’s breast tissue differentiating inflammatory and cancerous breast tissue from normal using the same camera used for MPI. These measured changes provided diagnostically useful information on cellular metabolism and regional blood flow changes (RBF) – the same properties which differentiate ischemic coronary artery disease (CAD) on myocardial perfusion imaging (MPI). Conclusions: Quantitative MBI using FMTVDM allows differentiation of tissue types through measurement of enhanced regional blood flow and metabolic differences. Nuclear cardiologists have previously reported cases of breast cancer while conducting MPI studies. This investigation demonstrated that nuclear cardiologists can independently conduct MBI in addition to MPI studies using the nuclear cameras they currently use for MPI.
背景:一项定量心肌灌注成像(MPI)和肿瘤学-包括分子乳腺成像(MBI) -实用专利(FMTVDM*)先前在经验丰富的MPI和MBI中心得到验证,目前在内华达州里诺市的一家私人诊所心脏病专家办公室独立测试用于临床应用。方法:使用FMTVDM,一位私人执业心脏病专家独立调查了12名具有不同过渡性乳房变化水平(包括乳腺癌)的妇女的44个感兴趣区域(ROI)。结果:使用FMTVDM,没有MBI经验的核心脏病专家能够使用与MPI相同的相机轻松测量女性乳腺组织的变化,以区分炎症和癌性乳腺组织与正常乳腺组织。这些测量的变化提供了关于细胞代谢和区域血流变化(RBF)的诊断有用信息-心肌灌注成像(MPI)区分缺血性冠状动脉疾病(CAD)的相同特性。结论:使用FMTVDM的定量MBI可以通过测量增强的区域血流和代谢差异来区分组织类型。核心脏病专家在进行MPI研究时曾报道过乳腺癌病例。这项调查表明,核心脏病专家可以独立进行MBI和MPI研究,使用核照相机,他们目前使用的MPI。
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引用次数: 0
A Recent Case Reports on Unfamiliar Kikuchi-Fujimoto Disease 最近报道一例不熟悉的菊chi-藤本病
Pub Date : 2019-03-15 DOI: 10.36648/2471-299X.5.1.77
J. Kaur, A. K. Wani, B. K. Yadav, Bhuban Subedi
Kikuchi-Fujimoto Disease (KFD) also known by a name called Histiocytic Necrotizing Lymphadenitis. It is very rare, non-cancerous and self-limiting Auto-Immune disease but most suspected as to be cancer, tuberculosis and systemic lupus erythematosus. It has symptoms such as cervical lymphadenopathy (enlargement of lymph nodes), low fever, headache, fatigue, night sweats, and muscles pain. It typically affects young females aged between 20-35 years and it mostly affects Asian populations. The correct identification of KFD is characterized by Fine Needle Aspiration Cytology by taking a blood sample from the swollen lymph node. Diagnosis is also possible with Fine Needle Aspiration Biopsy. Treatment for this disease has not been established. Non-steroidal Anti-Inflammatory Drugs or steroids are in use to ease tenderness of lymph node and fever.
菊池-藤本病(KFD)也被称为组织细胞坏死性淋巴结炎。它是一种非常罕见的非癌性和自限性自身免疫性疾病,但大多数怀疑为癌症,结核病和系统性红斑狼疮。它的症状包括颈部淋巴结肿大、低烧、头痛、疲劳、盗汗和肌肉疼痛。它通常影响20-35岁的年轻女性,主要影响亚洲人群。正确鉴别KFD的特点是细针抽吸细胞学,从肿胀的淋巴结取血样。细针穿刺活检也可诊断。这种疾病的治疗方法尚未确定。非甾体抗炎药或类固醇用于缓解淋巴结的压痛和发烧。
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引用次数: 1
A Clinical Review of First Seizures in Adult Patients 成人患者首次癫痫发作的临床回顾
Pub Date : 2019-01-01 DOI: 10.36648/2471-299x.5.2.78
Jose de Jesus Vidal Mayo
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引用次数: 1
How to Deal with Graft Ischemia While Performing Colon Interposition for Esophageal Reconstruction 结肠间置食管重建术中如何处理移植物缺血
Pub Date : 2019-01-01 DOI: 10.36648/2471-299X.5.1.76
A. Boukerrouche
The colon has become an effective and reliable graft for esophageal reconstruction. The in-depth knowledge of colon vascular anatomy is very essential to select an optimal graft. However, the colon interposition remains a surgical procedure associated with a high risk of graft ischemia. The graft ischemia is a dreaded complication which can impact the graft viability and the surgical outcomes. Various investigations have been used to assess graft blood supply and confirm the diagnosis of ischemia during colon interposition .Several strategies have been described to deal with this complication when it occurs intraoperatively. According to the patient conditions, the surgeon should be able to define the appropriate treatment strategy to deal with this complication. As colon interposition is a high-risk procedure, the preoperative identification of the risk factors, optimization of patient condition, and meticulous operative technique are required to reduce the risk of graft ischemia while selecting a colon graft for esophageal reconstruction.
结肠已成为食道重建的有效和可靠的移植物。深入了解结肠血管解剖学是选择最佳移植物的必要条件。然而,结肠介入术仍然是一种与移植物缺血高风险相关的外科手术。移植物缺血是影响移植物生存能力和手术效果的严重并发症。各种研究已被用于评估移植物血供和确认结肠介入期间缺血的诊断,并描述了处理术中发生这种并发症的几种策略。根据患者的情况,外科医生应该能够确定适当的治疗策略来处理这种并发症。结肠介入手术是一项高风险手术,在选择结肠移植物进行食管重建时,需要在术前明确危险因素、优化患者条件和细致的手术技术,以降低移植物缺血的风险。
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引用次数: 0
Role of Q-Waves ECG in Myocardial Scar Assessment in patients with Prior Myocardial Infarction q波心电图在既往心肌梗死患者心肌疤痕评估中的作用
Pub Date : 1900-01-01 DOI: 10.36648/2471-299X.5.2.79
Lucia Pv, Anna Ll, Catherine K, Tiziano M, Francesco Ff
This study was designed to assess the sensitivity and specificity of the pathological Q waves as defined in Electrocardiogram (ECG) criteria of European Society Guidelines (ESC) in myocardial scar assessment in patients with prior myocardial infarction. In common clinical practice, Q waves, or QS complexes in the absence of QRS confounders are pathognomonic of prior Myocardial Infarction (MI) in patients with chronic Ischemic Heart Disease (IHD) regardless of symptoms. Prior MI is characterized by the presence of scar. Cardiac Magnetic Resonance (cMRI) Late Gadolinium Enhancement (LGE) is considered the gold standard technique for the detection of myocardial scar. Data was collected on 500 patients referred for a 3 Tesla cMRI viability study. A 12-ECG lead was recorded in each patient. Sensitivity and specificity of wallspecific ECG changes in presence of 2+ or 3+ pathological Q waves in the corresponding wall leads have been evaluated for anterior (V1-V4 leads), inferior (D2, DIII, aVF leads) and lateral (D1, aVL, V5-V6 leads) wall in patients with transmural infarction, defined as >50% LGE. The sensitivity and specificity of wall-specific ECG changes in presence of 2+ pathological Q-waves were 42% and 88% for anterior, 43% and 69.9% for inferior and 28.6% and 76% for lateral wall; in presence of 3+ Q waves they were 24% and 95% for anterior, 27.8% and 82.5% for inferior and 9.5% and 93.8% for lateral wall. This study suggests that Q waves ESC ECG criteria may be a poor marker for detecting myocardial scar in patients with prior MI.
本研究旨在评估欧洲社会指南(ESC)心肌疤痕评估患者心电图(ECG)标准中病理Q波的敏感性和特异性。在常见的临床实践中,在没有QRS混杂因素的情况下,Q波或QS复合物是慢性缺血性心脏病(IHD)患者既往心肌梗死(MI)的病理特征,无论症状如何。先前的心肌梗死以存在疤痕为特征。心脏磁共振(cMRI)晚期钆增强(LGE)被认为是检测心肌瘢痕的金标准技术。收集了500名患者的数据,进行了3特斯拉cMRI活力研究。每例患者记录12个心电图导联。对于定义为LGE >50%的跨壁梗死患者的前壁(V1-V4导联)、下壁(D2、DIII、aVF导联)和侧壁(D1、aVL、V5-V6导联),评估相应壁导联出现2+或3+病理性Q波时壁特异性ECG变化的敏感性和特异性。2+病理性q波存在时,壁特异性心电图变化的敏感性和特异性分别为前壁42%和88%,下壁43%和69.9%,侧壁28.6%和76%;3+ Q波存在时,前壁分别为24%和95%,下壁分别为27.8%和82.5%,侧壁分别为9.5%和93.8%。本研究提示,对于既往心肌梗死患者,Q波ESC心电图标准可能是一个较差的检测心肌疤痕的指标。
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引用次数: 3
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Clinical Medical Reviews and Reports
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