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The Feasibility of an Educational Cartoon Video for Improving Adherence with Amblyopia Treatment in Children. 教育卡通视频提高儿童弱视治疗依从性的可行性。
IF 2.2 Q3 OPHTHALMOLOGY Pub Date : 2023-01-01 DOI: 10.2147/OPTH.S415892
Saeed Aljohani, Jingyun Wang, Mitchell Scheiman, Qing-Qing Tan, Hongxin Xu, Nawaf Almutairi, Saleh Alshammeri

Background: Previous studies have shown that it is necessary to evaluate adherence during the treatment process, using educational intervention methods which have been shown to improve adherence with patching treatment. A previous study reported that an educational cartoon had significantly improved adherence with patching. However, this black-white cartoon is not commercially available.

Objective: This study investigates the feasibility of a 4-minute educational cartoon video in improving adherence with patching therapy for amblyopic children.

Methods: Children (3 to 10 years old) with unilateral amblyopia who were prescribed 2 hours or 6 hours of patching per day were enrolled. Objective adherence to the treatment was tracked using a microsensor. Children returned after 4 weeks ± 2 days to measure adherence. Participants with adherence ≤50% were eligible to watch the educational cartoon video. They continued with the previously prescribed treatment (2 hours or 6 hours patching) for an additional week to evaluate the follow-up adherence.

Results: A total of 27 participants were enrolled. The mean age (SD) was 6.6 (1.5) years. Twenty-two participants (12 in the 2 hours patching group and 10 in the 6 hours patching group) had adherence ≤50% and watched our cartoon video. The cartoon video improved mean adherence (SD) from 29.6% (11.9%) to 56.8% (12.1%) in all 22 participants from both regimens (paired 2-tailed t-test, t= -11, P < 0.000).

Conclusion: The Educational cartoon video is feasible for use in a clinical setting. These data showed a trend of improvement in adherence with both patching regimens in children after watching the educational cartoon video.

背景:以往的研究表明,有必要在治疗过程中评估依从性,使用教育干预方法已被证明可以提高贴片治疗的依从性。先前的一项研究报告说,教育卡通能显著提高贴片的依从性。然而,这种黑白漫画并不是市售的。目的:探讨一段4分钟的教育卡通短片对提高弱视儿童贴片治疗依从性的可行性。方法:选取3 ~ 10岁单侧弱视儿童,每天配片2小时或6小时。使用微传感器跟踪治疗的客观依从性。儿童在4周±2天后返回以测量依从性。依从性≤50%的参与者有资格观看教育卡通视频。他们继续先前规定的治疗(2小时或6小时补片)额外一周,以评估随访依从性。结果:共纳入27名受试者。平均年龄(SD) 6.6(1.5)岁。22名受试者(2小时补片组12名,6小时补片组10名)的依从性≤50%,并观看了我们的卡通视频。卡通视频将两种方案的22名参与者的平均依从性(SD)从29.6%(11.9%)提高到56.8%(12.1%)(配对双尾t检验,t= -11, P < 0.000)。结论:教学卡通视频在临床应用是可行的。这些数据显示,在观看教育卡通视频后,儿童对两种贴片方案的依从性都有改善的趋势。
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引用次数: 0
Characteristics of Cellular Infiltration into Posterior Vitreous in Eyes with Uveitis on the Classification Basis Assessed Using Optical Coherence Tomography. 光学相干断层扫描评价葡萄膜炎后玻璃体细胞浸润的分类特征。
IF 2.2 Q3 OPHTHALMOLOGY Pub Date : 2023-01-01 DOI: 10.2147/OPTH.S394441
Wataru Matsumiya, Sentaro Kusuhara, Noriyuki Sotani, Kyung Woo Kim, Ryuto Nishisho, Rei Sotani, Hisanori Imai, Akihito Uji, Makoto Nakamura

Purpose: To evaluate the characteristics of posterior vitreous cells in patients with uveitis on the classification basis using spectral domain optical coherence tomography (SD-OCT).

Methods: In this retrospective chart review, all eyes were classified into three groups: infectious uveitis (IFU, n=7), noninfectious granulomatous uveitis (NIGU, n=13), and noninfectious nongranulomatous uveitis (NINGU, n=13). We measured the size, number, and density of vitreous hyperreflective particles in the posterior vitreous area that was defined as the space between the vitreous top and the internal limiting membrane on OCT. The correlations between vitreous haze and vitreous particles were also evaluated.

Results: Thirty-three eyes from 23 patients with active posterior uveitis were included. IFU had significantly more particles than NIGU and NINGU (P=0.03 and P<0.001, respectively). The vitreous particle density was higher in IFU than in NIGU and NINGU (P=0.03 and P=0.003, respectively). The mean largest particle size was greater in IFU and NIGU than in NINGU (P=0.01 and P=0.03, respectively). The median vitreous haze of 2+ in IFU, 1+ in NIGU and NINGU showed no significant difference among three groups (P=0.21). Conversely, the correlation of the largest particle size with vitreous haze was significant at ρ= 0.44 (P=0.01).

Conclusion: SD-OCT may be useful for assessing ocular inflammation based on morphological characteristics of vitreous particles on the uveitis classification basis.

目的:应用光谱域光学相干断层扫描(SD-OCT)对葡萄膜炎患者后玻璃体细胞的分类特征进行评价。方法:将所有眼睛分为感染性葡萄膜炎(IFU, n=7)、非感染性肉芽肿性葡萄膜炎(NIGU, n=13)和非感染性非肉芽肿性葡萄膜炎(NINGU, n=13) 3组。我们测量了玻璃体后区(定义为玻璃体顶部与内限定膜之间的空间)玻璃体高反射颗粒的大小、数量和密度,并评估了玻璃体雾霾与玻璃体颗粒之间的相关性。结果:纳入23例活动性后葡萄膜炎患者33只眼。IFU的颗粒含量显著高于NIGU和NINGU (P=0.03, PP=0.03, P=0.003)。IFU和NIGU的平均最大粒径大于NINGU (P=0.01和P=0.03)。IFU、NIGU、NINGU中位玻璃体雾度为2+,三组间差异无统计学意义(P=0.21)。相反,最大粒径与玻璃状雾霾的相关性显著,ρ= 0.44 (P=0.01)。结论:在葡萄膜炎分类的基础上,基于玻璃体颗粒的形态特征,SD-OCT可用于评估眼部炎症。
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引用次数: 2
Comparison of Phacoemulsification Grooving Efficiency in Longitudinal vs Transversal Handpieces. 纵向与横向手机超声乳化开槽效率的比较。
IF 2.2 Q3 OPHTHALMOLOGY Pub Date : 2023-01-01 DOI: 10.2147/OPTH.S391928
Samuel W Wilkinson, Emilie L Ungricht, William B West, Jacob T Harris, Brian Zaugg, Randall J Olson, Jeff H Pettey

Purpose: To determine the difference, if any, in grooving efficiency at various settings on the Whitestar Signature Pro phacoemulsification (phaco) system.

Methods: Cataractous lenses were simulated by exposing porcine lenses to formalin for 2 hours. A total of 120 lenses were analyzed at various power settings on both longitudinal and transversal handpieces. Twenty trials each were performed with power set to 25%, 50%, and 75% on both handpieces. A Whitestar Phaco Handpiece System was used to provide longitudinal power, and a Whitestar Signature Ellipsis Handpiece provided transversal power. Lenses were placed within a plastic chamber and grooved by an investigator blinded to settings. A second investigator recorded times and adjusted settings. The Whitestar Signature Pro phaco system was used for grooving.

Results: There was no significant difference in grooving times between the longitudinal and transverse handpieces at any power setting (P > 0.05). There was a significant decrease in grooving times when comparing the 25% power setting with the 75% power setting for the transversal handpiece (P=0.021).

Conclusion: Both longitudinal and transversal handpieces on the Whitestar Signature Pro phaco system produce similar results to one another at each power setting. There is a general trend toward shorter grooving times, reflecting greater efficiency, at higher power settings. Grooving efficiency on the transversal handpiece may be more affected by changes in the power settings as compared with the longitudinal settings.

目的:确定白星Signature Pro超声乳化(phaco)系统在不同设置下开槽效率的差异。方法:将猪晶状体暴露于福尔马林中2小时,模拟白内障晶状体。在纵向和横向手机的不同功率设置下,总共分析了120个镜头。各进行了20次试验,两部手机的功率分别设置为25%、50%和75%。使用白星phaaco手机系统提供纵向电源,使用白星Signature Ellipsis手机提供横向电源。透镜被放置在一个塑料腔内,并由一个不知道设置的研究者开槽。另一名调查员记录了时间并调整了设置。使用Whitestar Signature Pro phaco系统进行开槽。结果:在任意功率设置下,纵向与横向手刀开槽次数差异无统计学意义(P > 0.05)。当横向机头的25%功率设置与75%功率设置相比,开槽次数显著减少(P=0.021)。结论:在每个功率设置下,白星Signature Pro phaco系统上的纵向和横向手机产生相似的结果。在更高的功率设置下,总的趋势是更短的开槽时间,反映出更高的效率。与纵向设置相比,横向机头上的开槽效率可能更受功率设置变化的影响。
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引用次数: 0
Emerging Treatment Options for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration. 年龄相关性黄斑变性继发的地理萎缩(GA)的新治疗方案。
IF 2.2 Q3 OPHTHALMOLOGY Pub Date : 2023-01-01 DOI: 10.2147/OPTH.S367089
Hannah Khan, Aamir A Aziz, Humza Sulahria, Huma Khan, Abrahim Ahmed, Netan Choudhry, Raja Narayanan, Carl Danzig, Arshad M Khanani

Age-related macular degeneration (AMD) is characterized as a chronic, multifactorial disease and is the leading cause of irreversible blindness. Advanced AMD is classified as neovascular (wet) AMD and non-neovascular (dry) AMD. Dry AMD can progress to a more advanced form that manifests as geographic atrophy (GA), which significantly threatens vision, leading to progressive and irreversible loss of visual function. There are currently no approved therapeutics commercially available for GA patients. However, data from various clinical trials have demonstrated favorable results with significant reduction in GA lesion growth. This review furthers the understanding of the pathophysiology of GA, as well as current clinical trial data on investigational therapeutics.

年龄相关性黄斑变性(AMD)是一种慢性、多因素疾病,是导致不可逆失明的主要原因。晚期AMD分为新生血管性(湿性)AMD和非新生血管性(干性)AMD。干性AMD可以发展为更高级的形式,表现为地理萎缩(GA),严重威胁视力,导致视觉功能的进行性和不可逆转的丧失。目前还没有商业上批准的治疗GA患者的药物。然而,来自各种临床试验的数据表明,GA病变生长显著减少的有利结果。这篇综述进一步加深了对GA病理生理学的理解,以及目前研究治疗的临床试验数据。
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引用次数: 4
Association of Triglyceride Glucose Index with Prevalence and Incidence of Diabetic Retinopathy in a Singaporean Population. 新加坡人群中甘油三酯葡萄糖指数与糖尿病视网膜病变患病率和发病率的关系
IF 2.2 Q3 OPHTHALMOLOGY Pub Date : 2023-01-01 DOI: 10.2147/OPTH.S382336
Kumari Neelam, Khin Chaw Yu Aung, Keven Ang, Subramaniam Tavintharan, Chee Fang Sum, Su Chi Lim

Objective: To examine the association of triglyceride glucose (TyG) index (product of fasting triglyceride and glucose) with prevalence and incidence of diabetic retinopathy (DR) in type 2 diabetes.

Methods: 1339 patients from an ongoing Singapore Study of Macro-angiopathy and Micro-Vascular Reactivity in Type 2 Diabetes (SMART2D) were included in this study. Fasting triglyceride and glucose levels were quantified and color fundus photographs were assessed for DR presence and severity. Logistic regression models were used to evaluate associations of TyG index with DR prevalence and incidence (median follow-up period = 3.2 years).

Results: Mean TyG index was higher in patients with DR than no DR (9.24±0.7 versus 9.04± 0.6, p<0.001). TyG index was significantly associated with DR prevalence (OR=1.4, CI 1.1-1.7, p=0.002) and incidence (OR=1.8, CI 1.04-2.9, p=0.03), after adjusting for confounders. In a stratified analysis, the association between TyG index and DR prevalence reached significance only in the subgroup with HbA1c levels < 7.0% (OR=2, CI 1.1-3.8, p=0.03). TyG index significantly predicted DR prevalence and incidence with area under receiver operating curve as 0.77 (CI 0.74-0.80, p <0.001) and 0.66 (CI 0.57-0.76, p value <0.01), respectively.

Conclusion: TyG index is a good predictor for DR prevalence and incidence. It can also be a secondary treatment target for patients with optimally controlled levels of HbA1c.

目的:探讨甘油三酯葡萄糖(TyG)指数(空腹甘油三酯与葡萄糖的乘积)与2型糖尿病糖尿病视网膜病变(DR)患病率和发病率的关系。方法:1339例患者来自正在进行的新加坡2型糖尿病大血管病变和微血管反应性研究(SMART2D)。空腹甘油三酯和葡萄糖水平被量化,眼底彩色照片被评估DR的存在和严重程度。采用Logistic回归模型评估TyG指数与DR患病率和发病率的关系(中位随访期= 3.2年)。结果:有DR患者的TyG指数高于无DR患者(9.24±0.7 vs 9.04±0.6)。结论:TyG指数是预测DR患病率和发病率的良好指标。它也可以作为HbA1c水平控制最佳的患者的次要治疗靶点。
{"title":"Association of Triglyceride Glucose Index with Prevalence and Incidence of Diabetic Retinopathy in a Singaporean Population.","authors":"Kumari Neelam,&nbsp;Khin Chaw Yu Aung,&nbsp;Keven Ang,&nbsp;Subramaniam Tavintharan,&nbsp;Chee Fang Sum,&nbsp;Su Chi Lim","doi":"10.2147/OPTH.S382336","DOIUrl":"https://doi.org/10.2147/OPTH.S382336","url":null,"abstract":"<p><strong>Objective: </strong>To examine the association of triglyceride glucose (TyG) index (product of fasting triglyceride and glucose) with prevalence and incidence of diabetic retinopathy (DR) in type 2 diabetes.</p><p><strong>Methods: </strong>1339 patients from an ongoing Singapore Study of Macro-angiopathy and Micro-Vascular Reactivity in Type 2 Diabetes (SMART2D) were included in this study. Fasting triglyceride and glucose levels were quantified and color fundus photographs were assessed for DR presence and severity. Logistic regression models were used to evaluate associations of TyG index with DR prevalence and incidence (median follow-up period = 3.2 years).</p><p><strong>Results: </strong>Mean TyG index was higher in patients with DR than no DR (9.24±0.7 versus 9.04± 0.6, p<0.001). TyG index was significantly associated with DR prevalence (OR=1.4, CI 1.1-1.7, p=0.002) and incidence (OR=1.8, CI 1.04-2.9, p=0.03), after adjusting for confounders. In a stratified analysis, the association between TyG index and DR prevalence reached significance only in the subgroup with HbA1c levels < 7.0% (OR=2, CI 1.1-3.8, p=0.03). TyG index significantly predicted DR prevalence and incidence with area under receiver operating curve as 0.77 (CI 0.74-0.80, p <0.001) and 0.66 (CI 0.57-0.76, p value <0.01), respectively.</p><p><strong>Conclusion: </strong>TyG index is a good predictor for DR prevalence and incidence. It can also be a secondary treatment target for patients with optimally controlled levels of HbA1c.</p>","PeriodicalId":10442,"journal":{"name":"Clinical ophthalmology","volume":"17 ","pages":"445-454"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/38/2c/opth-17-445.PMC9901446.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10681618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Macular Vascularity and Ganglion Cell Complex Parameters in the Young Adults with Myopia and Progressive Myopia. 青壮年近视和进行性近视的黄斑血管和神经节细胞复合体参数。
IF 2.2 Q3 OPHTHALMOLOGY Pub Date : 2023-01-01 DOI: 10.2147/OPTH.S389963
Artur Małyszczak, Magdalena Żyto, Joanna Przeździecka-Dołyk, Marta Misiuk-Hojło

Purpose: The purpose of this study is to determine the relationships between foveal avascular zone (FAZ), foveal vascular density (FD) and GCC (ganglion cell complex) parameters in a healthy myopic population using optical coherence tomography angiography (angio-OCT).

Patients and methods: Three hundred and eighty-one eyes of 381 healthy participants were included into this study and assigned to three groups according to their spherical equivalent (SE) values and an additional progressive myopia group. One randomly chosen eye from each patient was analyzed. GCC mean thickness, focal loss of volume (FLV), global loss of volume (GLV), FAZ area, FAZ perimeter, and FD parameters were obtained with the RTVue AngioOCT device.

Results: FAZ area and its perimeter were strongly correlated with the belonging spherical equivalent group (p = 0.0001, p = 0.0008 accordingly), being the largest in progressive myopia subgroup (mean size 0.42mm2). Other factors that were significantly higher in myopic eyes were FLV (p = 0.0023), GLV (p = 0.0020). There were no differences in FD between groups. In the myopic and progressive myopia groups, there was a significant relationship between FAZ area and FLV, GLV, and GCC thickness. We found that in myopic eyes with AXL exceeding 26.6 mm, FAZ becomes negatively correlated to mean GCC thickness.

Conclusion: In myopia, compared to non-myopic groups, there is a greater loss of neural tissue represented by a thinner GCC layer, greater FLV and GLV parameters, and worse blood supply represented by a larger FAZ area. Eye axial length of 26.6 mm is a breaking point, where the negative FAZ area to GCC thickness relationship curve is getting significantly steeper.

目的:本研究的目的是利用光学相干断层扫描血管成像(angio-OCT)确定健康近视人群的中央凹无血管带(FAZ)、中央凹血管密度(FD)和神经节细胞复合体(GCC)参数之间的关系。患者和方法:381名健康参与者的381只眼睛被纳入本研究,并根据其球体等效(SE)值分为三组和另一组进行性近视组。从每位患者随机选择一只眼睛进行分析。使用RTVue AngioOCT装置获得GCC平均厚度、局部体积损失(FLV)、整体体积损失(GLV)、FAZ面积、FAZ周长和FD参数。结果:FAZ面积及其周长与属于球形等效组有较强的相关性(p = 0.0001, p = 0.0008),在进展性近视亚组中最大(平均大小0.42mm2)。近视眼中FLV (p = 0.0023)、GLV (p = 0.0020)等因素显著升高。两组间FD无差异。在近视组和进行性近视组中,FAZ面积与FLV、GLV和GCC厚度有显著相关。我们发现,在AXL超过26.6 mm的近视眼,FAZ与平均GCC厚度呈负相关。结论:与非近视组相比,近视组神经组织损失更大,表现为GCC层更薄,FLV和GLV参数更大,血供更差,表现为FAZ面积更大。眼轴长度为26.6 mm为断点,此时负FAZ面积与GCC厚度的关系曲线明显变陡。
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引用次数: 0
Preventing Retinal Detachment: The Encircling Laser Retinopexy Technique. 预防视网膜脱离:激光视网膜环切术。
IF 2.2 Q3 OPHTHALMOLOGY Pub Date : 2023-01-01 DOI: 10.2147/OPTH.S406337
Robert E Morris, Ferenc Kuhn, Cole Richardson

Encircling (360 degree) retinal detachment prophylaxis using indirect ophthalmoscope laser delivery recently achieved strong proof of safety and effectiveness by preventing the development of peripheral retinal tears and detachments in the eyes of patients with Stickler syndrome (syndromic eyes). Untreated, Stickler syndrome patients have a 65% lifetime risk of retinal detachment (half by age 20, 80% bilateral). This report describes an optimal technique of encircling laser retinopexy to also prevent the more common retinal detachments seen in aging (non-syndromic) eyes that share with Stickler syndrome the common pathogenesis of peripheral retinal tears caused by vitreous traction.

最近,间接检眼镜激光治疗预防Stickler综合征(综合征型眼)患者周围视网膜撕裂和脱离的安全性和有效性得到了强有力的证明。未经治疗,Stickler综合征患者有65%的终生视网膜脱离风险(一半到20岁,80%双侧)。本报告描述了一种最佳的激光视网膜环切术,以防止与Stickler综合征(玻璃体牵拉引起的周围视网膜撕裂的常见发病机制)相同的老化(无综合征)眼睛中更常见的视网膜脱离。
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引用次数: 1
Carotid-Cavernous Fistulas: The Utility of Ocular Echography in Their Differentiation [Letter]. 颈动脉-海绵状瘘管:眼超声鉴别的应用[字母]。
IF 2.2 Q3 OPHTHALMOLOGY Pub Date : 2023-01-01 DOI: 10.2147/OPTH.S420582
Mario Graziano, Danilo Biondino, Isabella Fioretto
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引用次数: 0
Short-Term Total Tamponade with Perfluorocarbon Liquid and Silicone Oil in Complex Rhegmatogenous Retinal Detachment with Severe Proliferative Vitreoretinopathy. 全氟碳液联合硅油短期全填塞治疗复杂孔源性视网膜脱离伴严重增殖性玻璃体视网膜病变。
IF 2.2 Q3 OPHTHALMOLOGY Pub Date : 2023-01-01 DOI: 10.2147/OPTH.S400156
Omar Trabelsi, Mejda Bouladi, Amel Ouertani, Ahmed Trabelsi

Background: To evaluate retinal reattachment, visual functional results, and complications rates after total tamponade (TT) with perfluorocarbon liquid (PFCL) and silicone oil (SO) for 2 days followed by PFCL-SO exchange in complex retinal detachment (RD).

Methods: Retrospective study including 52 consecutive eyes with complex RD and advanced proliferative vitreoretinopathy, who underwent vitrectomy with TT. Patients underwent first surgery by 25-Gauge vitrectomy and partial PFCL-SO exchange (approximately 60% PFCL 40% SO fill) followed by second surgery with extraction of the PFCL and complete SO fill.

Results: After a mean follow-up period of 25.15 ± 6.6 months, the retina remained reattached in 48/52 eyes (92.3%) including 28 eyes (58.3%) without SO and 20 eyes (41.7%) with prolonged SO tamponade. Visual acuity improved in 45 eyes (86.6%) (P<0.001), remained stable in 4 eyes (7.7%) and decreased in 3 eyes (5.7%). Complications consisted in mild anterior chamber inflammation in 10 eyes, ocular hypertension in 12 eyes, and cataract in 10 eyes.

Conclusion: Two-day TT with PFCL and SO may be considered in complex RD with advanced proliferative vitreoretinopathy especially in monocular patients. Further studies with longer follow-up period and retinal electrophysiologic assessment may be needed.

背景:评价全氟化碳液体(PFCL)和硅油(SO)全压塞(TT) 2天后PFCL-SO交换对复杂视网膜脱离(RD)的视网膜再附着、视觉功能结果和并发症发生率。方法:回顾性研究连续52眼复杂RD合并晚期增殖性玻璃体视网膜病变行玻璃体切除术的患者。患者首先接受25号玻璃体切除术和部分PFCL-SO交换(约60% PFCL 40% SO填充),然后进行第二次手术,取出PFCL和完全SO填充。结果:平均随访25.15±6.6个月,48/52只眼(92.3%)的视网膜仍能附着,其中无SO的28只眼(58.3%),长时间SO填塞的20只眼(41.7%)。结论:对于合并晚期增殖性玻璃体视网膜病变的复杂RD患者,特别是单眼患者,可考虑两天TT联合PFCL和SO。可能需要更长的随访期和视网膜电生理评估的进一步研究。
{"title":"Short-Term Total Tamponade with Perfluorocarbon Liquid and Silicone Oil in Complex Rhegmatogenous Retinal Detachment with Severe Proliferative Vitreoretinopathy.","authors":"Omar Trabelsi,&nbsp;Mejda Bouladi,&nbsp;Amel Ouertani,&nbsp;Ahmed Trabelsi","doi":"10.2147/OPTH.S400156","DOIUrl":"https://doi.org/10.2147/OPTH.S400156","url":null,"abstract":"<p><strong>Background: </strong>To evaluate retinal reattachment, visual functional results, and complications rates after total tamponade (TT) with perfluorocarbon liquid (PFCL) and silicone oil (SO) for 2 days followed by PFCL-SO exchange in complex retinal detachment (RD).</p><p><strong>Methods: </strong>Retrospective study including 52 consecutive eyes with complex RD and advanced proliferative vitreoretinopathy, who underwent vitrectomy with TT. Patients underwent first surgery by 25-Gauge vitrectomy and partial PFCL-SO exchange (approximately 60% PFCL 40% SO fill) followed by second surgery with extraction of the PFCL and complete SO fill.</p><p><strong>Results: </strong>After a mean follow-up period of 25.15 ± 6.6 months, the retina remained reattached in 48/52 eyes (92.3%) including 28 eyes (58.3%) without SO and 20 eyes (41.7%) with prolonged SO tamponade. Visual acuity improved in 45 eyes (86.6%) (<i>P</i><0.001), remained stable in 4 eyes (7.7%) and decreased in 3 eyes (5.7%). Complications consisted in mild anterior chamber inflammation in 10 eyes, ocular hypertension in 12 eyes, and cataract in 10 eyes.</p><p><strong>Conclusion: </strong>Two-day TT with PFCL and SO may be considered in complex RD with advanced proliferative vitreoretinopathy especially in monocular patients. Further studies with longer follow-up period and retinal electrophysiologic assessment may be needed.</p>","PeriodicalId":10442,"journal":{"name":"Clinical ophthalmology","volume":"17 ","pages":"515-525"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6d/39/opth-17-515.PMC9922565.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10794019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long Term Clinical Outcomes of Hydrophilic and Hydrophobic Versions of a Trifocal IOL with the Same Optical Design. 具有相同光学设计的亲水型和疏水型三焦人工晶体的长期临床结果。
IF 2.2 Q3 OPHTHALMOLOGY Pub Date : 2023-01-01 DOI: 10.2147/OPTH.S403351
Robert Edward T Ang

Purpose: To show the visual and refractive outcomes in Asian eyes with cataract when bilaterally implanted with either a hydrophobic FineVision POD F GF or a hydrophilic FineVision POD F intraocular lens (IOL).

Methods: Forty-six patients were randomized to receive POD F GF or POD F IOLs. Visual and refractive outcomes were assessed up to 24 months post-surgery. Measurements included uncorrected-distance visual acuity, corrected-distance visual acuity (CDVA), distance-corrected intermediate visual acuity (DCIVA), distance-corrected near visual acuity (DCNVA), refraction, defocus curve, photopic and mesopic contrast sensitivity, and patient-reported outcomes.

Results: Mean spherical equivalent was close to emmetropia for both groups and stable across postoperative visits. Overall, 97.73% and 100% of eyes in the POD F GF IOL group and 95.65% and 100%, of eyes in the POD F IOL group were within ±1.00D of the target refraction at 12 and 24 months, respectively. All patients showed a CDVA of ≥20/25 at 12- and 24-months post-surgery. In both groups, 24 months post-surgery 91% of patients presented a DCIVA of ≥20/25 and 83.3% of patients had a DCNVA of ≥20/25. Defocus curve showed continuous visual acuity, being 20/32 or better in both groups over a 4.00D range between 1.00D and -3.00/-3.50D. Both groups showed good contrast sensitivity values for photopic and mesopic conditions. Overall, 86.4%, 86.4%, and 72.7% of patients implanted with the POD F GF IOL reported not wearing glasses at all for distance, intermediate, and near vision, respectively. These values were 81.8%, 86.4%, and 90.9% for patients implanted with the POD F IOL. Both groups of patients reported similar satisfaction percentages (100% very satisfied/satisfied) and would recommend the procedure (100% definitively yes/probably yes).

Conclusion: This study demonstrates good visual and refractive outcomes for both the FineVision POD F GF and the FineVision POD F IOLs when implanted in Asian eyes.

目的:观察亚洲白内障患者双侧植入疏水FineVision POD F GF或亲水性FineVision POD F人工晶状体(IOL)后的视力和屈光效果。方法:46例患者随机接受POD F GF或POD F iol治疗。术后24个月评估视力和屈光结果。测量包括未矫正距离视力、矫正距离视力(CDVA)、矫正距离中间视力(DCIVA)、矫正距离近视力(DCNVA)、屈光、离焦曲线、光和介观对比敏感度以及患者报告的结果。结果:两组患者的平均球当量接近斜视,术后随访稳定。总体而言,在12个月和24个月时,POD F GF IOL组97.73%和100%的眼距目标屈光度在±1.00D以内,POD F IOL组95.65%和100%。所有患者术后12个月和24个月的CDVA均≥20/25。两组患者术后24个月,91%的患者DCIVA≥20/25,83.3%的患者DCNVA≥20/25。离焦曲线显示视力连续,在1.00D至-3.00/-3.50D的4.00D范围内,两组视力均为20/32或更好。两组在光和介观条件下均表现出良好的对比感光度值。总体而言,86.4%、86.4%和72.7%植入POD F GF IOL的患者分别报告在远视、中视和近视时根本不戴眼镜。这些数值分别为81.8%、86.4%和90.9%。两组患者报告了相似的满意度百分比(100%非常满意/满意),并会推荐手术(100%肯定是/可能是)。结论:本研究表明FineVision POD F GF和FineVision POD F iol植入术在亚洲人眼中具有良好的视力和屈光效果。
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引用次数: 1
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Clinical ophthalmology
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