{"title":"Pilot projekt a diabeteses betegek influenza elleni védőoltásának hatékonyságáról","authors":"János Sándor, Marianna Szücs, László Kőrösi","doi":"10.24121/dh.2021.s1.32","DOIUrl":"https://doi.org/10.24121/dh.2021.s1.32","url":null,"abstract":"","PeriodicalId":104660,"journal":{"name":"Diabetologia Hungarica","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124445140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
On the occasion of the Somogyi Award lecture this review focusses on the current advances in tackling hypoglycemia in pediatric patients with type 1 diabetes providing evidence for the importance of multidisciplinary teams, ambitious glycemic targets and implementation of diabetes technology. Meal-related intensified insulin replacement with differential substitution of basal- and bolus insulin is the therapy of choice in the care of children and adolescents with type 1 diabetes. The use of insulin pumps and continuous glucose monitoring devices is increasing rapidly, with the type of insulin therapy (insulin pen or pump) depending on the age of the patients and family preference. Education appropriate to the age and current challenges is essential for the children's participation in everyday life as undisturbed as possible. New parameters like time in range and time below range suitable for identifying high glycemic variability as risk factor for severe hypoglycemia complement the HbA1c targets and the ambulatory glucose profile (AGP) in a shared decision making on therapeutic adjustments between the diabetes team and people with diabetes. Automated insulin delivery as a hybrid closed loop or dosing advice using artificial intelligence are becoming a clinical reality. However, diabetes education as a team approach, defining clear targets with outcomes evaluated in multinational registries like SWEET remain important for shaping the future of pediatric diabetology.
{"title":"Tackling hypoglycemia in children: teams, targets and technology","authors":"T. Danne","doi":"10.24121/dh.2021.1","DOIUrl":"https://doi.org/10.24121/dh.2021.1","url":null,"abstract":"On the occasion of the Somogyi Award lecture this review focusses on the current advances in tackling hypoglycemia in pediatric patients with type 1 diabetes providing evidence for the importance of multidisciplinary teams, ambitious glycemic targets and implementation of diabetes technology. Meal-related intensified insulin replacement with differential substitution of basal- and bolus insulin is the therapy of choice in the care of children and adolescents with type 1 diabetes. The use of insulin pumps and continuous glucose monitoring devices is increasing rapidly, with the type of insulin therapy (insulin pen or pump) depending on the age of the patients and family preference. Education appropriate to the age and current challenges is essential for the children's participation in everyday life as undisturbed as possible. New parameters like time in range and time below range suitable for identifying high glycemic variability as risk factor for severe hypoglycemia complement the HbA1c targets and the ambulatory glucose profile (AGP) in a shared decision making on therapeutic adjustments between the diabetes team and people with diabetes. Automated insulin delivery as a hybrid closed loop or dosing advice using artificial intelligence are becoming a clinical reality. However, diabetes education as a team approach, defining clear targets with outcomes evaluated in multinational registries like SWEET remain important for shaping the future of pediatric diabetology.","PeriodicalId":104660,"journal":{"name":"Diabetologia Hungarica","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123746308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Kovács, Gyorgy Eigner, Bence Czakó, Máté Siket, Zsuzsana Almássy, Győző Kocsis, László Barkai
Summary: The paper gives a short review on the artificial pancreas (AP), which can be used for automated treatment of diabetic patients. This highly interdisciplinary concept involves beyond medical sciences, control engineering and biomedical engineering knowledge. Having already developed continuous glucose sensor devices and highly performant insulin pumps, the AP can be an efficient solution for millions of people living with diabetes for accurate metabolic conditions management. Furthermore, as a semi-automatic device, AP can guarantee tight blood glucose control. In this paper, we summarize not just the AP concept, but give a short review on the modeling and control solutions as well. ami által a beteg vércukorszintje becsülhető a szen zor elektromos tulajdonságainak változása révén. Az enzim a glukóz glükonsavvá alakulását katalizálja, a reakcióban köz-vetetten elektromos töltés jön létre. Az elektródban létrejövő töltés nagyságából, megfelelő analóg és digitális jelfeldolgo zással számolható a becsült glukózkoncentráció.
{"title":"Mesterséges hasnyálmirigy – A cukorbetegség automatikus kezelése mérnöki megközelítéssel","authors":"L. Kovács, Gyorgy Eigner, Bence Czakó, Máté Siket, Zsuzsana Almássy, Győző Kocsis, László Barkai","doi":"10.24121/dh.2019.21","DOIUrl":"https://doi.org/10.24121/dh.2019.21","url":null,"abstract":"Summary: The paper gives a short review on the artificial pancreas (AP), which can be used for automated treatment of diabetic patients. This highly interdisciplinary concept involves beyond medical sciences, control engineering and biomedical engineering knowledge. Having already developed continuous glucose sensor devices and highly performant insulin pumps, the AP can be an efficient solution for millions of people living with diabetes for accurate metabolic conditions management. Furthermore, as a semi-automatic device, AP can guarantee tight blood glucose control. In this paper, we summarize not just the AP concept, but give a short review on the modeling and control solutions as well. ami által a beteg vércukorszintje becsülhető a szen zor elektromos tulajdonságainak változása révén. Az enzim a glukóz glükonsavvá alakulását katalizálja, a reakcióban köz-vetetten elektromos töltés jön létre. Az elektródban létrejövő töltés nagyságából, megfelelő analóg és digitális jelfeldolgo zással számolható a becsült glukózkoncentráció.","PeriodicalId":104660,"journal":{"name":"Diabetologia Hungarica","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123786178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Summary: Regular physical activity is an integral part of diabetes management and also plays an important role in diabetes prevention. Fear of hypoglycemia is the strongest barrier to regular physical activity in patients with type 1 diabetes. Sensor augmented insulin pump therapy can reduce the rate of severe and moderate hypoglycemia episodes compared with standard insulin and insulin pump (without sensor) therapy. Glycemic status of 15 young adults with type 1 diabetes during extreme physical activity was analysed in this study. Our results showed that sensor-augmented pump therapy re-duced the combined rate of severe (requiring help) and moderate hypoglycemia (accompanied with typical clinical signs) in patients with type 1 diabetes during extreme physical activity.
{"title":"Szenzorral támogatott inzulinpumpa használata extrém fizikai terhelés során 1-es típusú diabetes mellitusban","authors":"András Török, Pál Pál","doi":"10.24121/dh.2019.3","DOIUrl":"https://doi.org/10.24121/dh.2019.3","url":null,"abstract":"Summary: Regular physical activity is an integral part of diabetes management and also plays an important role in diabetes prevention. Fear of hypoglycemia is the strongest barrier to regular physical activity in patients with type 1 diabetes. Sensor augmented insulin pump therapy can reduce the rate of severe and moderate hypoglycemia episodes compared with standard insulin and insulin pump (without sensor) therapy. Glycemic status of 15 young adults with type 1 diabetes during extreme physical activity was analysed in this study. Our results showed that sensor-augmented pump therapy re-duced the combined rate of severe (requiring help) and moderate hypoglycemia (accompanied with typical clinical signs) in patients with type 1 diabetes during extreme physical activity.","PeriodicalId":104660,"journal":{"name":"Diabetologia Hungarica","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127405594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Hosszúfalusi, László Barkai, Emese Sipter, Dorottya Csuka, Tímea Baló, Krisztina Lukács, M. Kempler, P. Pánczél, Katrine Pilely, Peter Garred, Zoltán Prohászka
{"title":"Csökkent komplementaktivitás észlelhető 2-es típusú cukorbetegségben a nem cukorbetegekhez képest bakteriális infekciókban","authors":"N. Hosszúfalusi, László Barkai, Emese Sipter, Dorottya Csuka, Tímea Baló, Krisztina Lukács, M. Kempler, P. Pánczél, Katrine Pilely, Peter Garred, Zoltán Prohászka","doi":"10.24121/dh.2019.s1.12","DOIUrl":"https://doi.org/10.24121/dh.2019.s1.12","url":null,"abstract":"","PeriodicalId":104660,"journal":{"name":"Diabetologia Hungarica","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134403303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Molnár, G. Bánfai, P. Kanizsai, Csaba Csontos, Szilárd Kun, Ágnes Lakatos, Anikó Lajtai, A. Miseta, I. Wittmann
{"title":"Szérumglükózszint és plazmaaminosav-paraméterek a COVID-19-infekció kimenetelének lehetséges prediktorai","authors":"G. Molnár, G. Bánfai, P. Kanizsai, Csaba Csontos, Szilárd Kun, Ágnes Lakatos, Anikó Lajtai, A. Miseta, I. Wittmann","doi":"10.24121/dh.2021.s1.29","DOIUrl":"https://doi.org/10.24121/dh.2021.s1.29","url":null,"abstract":"","PeriodicalId":104660,"journal":{"name":"Diabetologia Hungarica","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132625902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Boncz, Diána Elmer, N. Németh, Zsuzsanna Kívés, I. Wittmann, Lilla Horváth, T. Csákvári
{"title":"A 2-es típusú diabetes mellitus és szövődményeinek epidemiológiai és betegségteher-vizsgálata rutinszerűen gyűjtött egészségbiztosítási adatok alapján","authors":"I. Boncz, Diána Elmer, N. Németh, Zsuzsanna Kívés, I. Wittmann, Lilla Horváth, T. Csákvári","doi":"10.24121/dh.2021.s1.7","DOIUrl":"https://doi.org/10.24121/dh.2021.s1.7","url":null,"abstract":"","PeriodicalId":104660,"journal":{"name":"Diabetologia Hungarica","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131209056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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