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Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles最新文献

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[Experimental dissociation between hippocampal theta activity in wakefulness and hippocampal theta activity in paradoxal sleep in the rat]. [大鼠清醒时海马体θ波活动与矛盾睡眠时海马体θ波活动的实验分离]。
Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles
Pub Date : 1978-10-30
P Monmaur, O Houcine, J Delacour

The effects of electrolytic lesion of the septum on the theta activity of the dorsal hippocampus were studied in the chronically implanted Rat during wakefulness and paradoxical sleep. The experimental results show that depending on its localization, septal lesion can either: (1) eliminate the wakefulness theta rhythm without suppressing that of paradoxical sleep; (2) eliminate the paradoxical sleep theta rhythm without suppressing that of wakefulness. These results suggest that there are two kinds of theta activity having different anatomophysiological bases and a different functional significance: one associated with wakefulness and the other with paradoxical sleep.

研究了慢性植入大鼠在清醒和矛盾睡眠状态下，中隔电损伤对海马背侧θ波活动的影响。实验结果表明，根据其定位的不同，间隔损伤可以:(1)在不抑制矛盾睡眠的情况下消除清醒θ节律;(2)在不抑制清醒状态的情况下消除矛盾的睡眠θ节律。这些结果表明，存在两种具有不同解剖生理学基础和不同功能意义的θ波活动:一种与清醒有关，另一种与矛盾睡眠有关。
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引用次数: 0
[Study of the Gc protein in several French population samples : genetic polymorphism by isoelectrofocusing and quantitative results]. [几个法国人群样品中Gc蛋白的研究:等电聚焦和定量结果的遗传多态性]。
Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles
Pub Date : 1978-10-30
J Constans, M Viau, J Ruffié

The authors describe the results obtained in an examination by isoelectrofocusing of more than 1,000 serum samples from various regions in France. The autochthonous populations of the north side of the Pyrénées are characterized by a high frequency of the gene Gc2 and a very low frequency of the Gc1F gene. This distinguishes them from the other groups studied (southwestern, northwestern and eastern France). The quantitative analysis of the data emphasizes the difference. These results can only be explained by the interdependance of the genetic and metabolic factors.

作者描述了在法国不同地区的1000多个血清样本的等电聚焦检查中获得的结果。pyr 和 /或所有其他地区的土著群体的特征是基因Gc2频率高，而基因Gc1F频率极低。这将他们与其他研究群体(法国西南部、西北部和东部)区分开来。数据的定量分析强调了差异。这些结果只能通过遗传和代谢因素的相互依赖来解释。
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引用次数: 0
[Histo-enzymatic localization of xanthine oxidase in human and rat tissues]. 黄嘌呤氧化酶在人和大鼠组织中的组织酶定位。
Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles
Pub Date : 1978-10-30
N Amory, F Delbarre, C Auscher
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引用次数: 0
[Ultrastructural study of the virus genome of fowl myelocytomatosis (MC 29)]. 禽髓细胞瘤病(mc29)病毒基因组的超微结构研究
Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles
Pub Date : 1978-10-30
J Gogusev, U Heine
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引用次数: 0
[Criteria for the evaluation of the antirheumatic (antiinflammatory) drugs in man]. [人类抗风湿(抗炎)药物评价标准]。
Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles
Pub Date : 1978-10-23
F Delbarre, C Mery, J P Nakache, A de Géry, C Chastang

Comparison of 5 antiinflammatory drugs and placebo in a double blind, short term, cross-over trial conducted in patients suffering from rheumatoid arthritis. 15 measurements were used and studied. With classical unidimensional statistical tests it was not possible to discriminate active drugs between them. Multidimensional analysis (correspondance analysis and discriminant analysis) are more sensitive and allow us to distinguish active drugs with only 11 criterion.

在类风湿关节炎患者中进行的一项双盲、短期交叉试验中5种抗炎药物与安慰剂的比较使用和研究了15种测量方法。用经典的单维统计检验不可能区分它们之间的活性药物。多维分析(对应分析和判别分析)更灵敏，仅用11个标准就能区分出活性药物。
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引用次数: 0
[I and i antigens of human erythrocytes : their detection by means of immunofluorescence technic and their changes during ontogenesis]. 人红细胞I和I抗原:免疫荧光技术检测及其在个体发生过程中的变化。
Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles
Pub Date : 1978-10-23
J P Blanchet, C Doinel

I and i antigens were detected by indirect immunofluorescence on human erythrocytes. 80% of the cord blood cells were brightly fluorescent with anti-i, 15% only with anti-I. In adult blood, this ratio is reversed, 2% only of the cells being intensively labelled with anti-i. The percentages characteristic of adult blood are established within the first 8 months of life.

用间接免疫荧光法在人红细胞上检测I和I抗原。80%的脐带血细胞在抗i抗体作用下呈明亮荧光，15%的脐带血细胞仅在抗i抗体作用下呈明亮荧光。在成人血液中，这一比例相反，只有2%的细胞被密集地标记为抗i。成人血液的百分比特征是在生命的前8个月内确定的。
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引用次数: 0
[Role of the Raphe Magnus nucleus in morphine analgesia : studies with intracerebral microinjections in the rat]. [中缝大核在吗啡镇痛中的作用:大鼠脑内显微注射的研究]。
Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles
Pub Date : 1978-10-23
A H Dickenson, J L Oliveras, J M Besson

Microinjections of low concentration of morphine (5 micrograms) into the nucleus Raphé Magnus of the Rat produce a strong analgesia that can be reversed by systemic naloxone, an opiate antagonist. The administration of naloxone (5 micrograms) into the Raphé Magnus considerably reduces the effects of intravenous morphine. The effects of microinjections of morphine are strongly reduced by Cinanserin, suggesting a role for serotoninergic mechanisms in morphine analgesia.

将低浓度的吗啡(5微克)微量注射到大鼠的大鼠核中会产生强烈的镇痛作用，这种镇痛作用可以被全身的纳洛酮(一种阿片类拮抗剂)逆转。纳洛酮(5微克)的管理，以拉斐尔Magnus显著降低静脉注射吗啡的影响。微注射吗啡的效果明显降低，提示5 -羟色胺能机制在吗啡镇痛中的作用。
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引用次数: 0
[Purification of streptolysin O by covalent chromatography on thiol-agarose gel]. [巯基琼脂糖凝胶共价层析纯化链溶素O]。
Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles
Pub Date : 1978-10-23
D Prigent, C Geoffroy, J E Alouf
{"title":"[Purification of streptolysin O by covalent chromatography on thiol-agarose gel].","authors":"D Prigent,&nbsp;C Geoffroy,&nbsp;J E Alouf","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":10544,"journal":{"name":"Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles","volume":"287 10","pages":"951-4"},"PeriodicalIF":0.0,"publicationDate":"1978-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11327059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Perhexiline-maleate-induced lipidosis in mouse spinal ganglia tissue culture. Preliminary results on the acute toxicity on the drug]. 过己胺-马来酸诱导小鼠脊髓神经节组织培养的脂质沉积。药物急性毒性的初步结果。
Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles
Pub Date : 1978-10-23
J J Hauw, J M Boutry, S Hamam, R Escourolle
{"title":"[Perhexiline-maleate-induced lipidosis in mouse spinal ganglia tissue culture. Preliminary results on the acute toxicity on the drug].","authors":"J J Hauw,&nbsp;J M Boutry,&nbsp;S Hamam,&nbsp;R Escourolle","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":10544,"journal":{"name":"Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles","volume":"287 10","pages":"959-61"},"PeriodicalIF":0.0,"publicationDate":"1978-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11327061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Identification of GABA accumulating neurons in the dorsal raphe nucleus]. [中缝背核GABA积累神经元的鉴定]。
Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles
Pub Date : 1978-10-16
M F Belin, M Aguera, M Tappaz, M Jouvet, J F Pujol

A possible GABAergic innervation of the nucleus raphe dorsalis (NRD) was investigated by measuring glutamate decarboxylase activity in the NRD after lesioning the afferents of this nucleus. The slight decrease found in the enzymatic activity suggests that these afferents have a minor participation in the GABA innervation of the NRD and implies the existence of an intrinsic GABAergic system in this nucleus. This local innervation was demonstrated by radio-autography and shows fibers, axonal varicosities and cell bodies which accumulate 3H GABA in the caudal part of this nucleus.

通过测定背中缝核传入神经损伤后的谷氨酸脱羧酶活性，探讨了背中缝核可能存在的gaba能神经支配。酶活性的轻微下降表明这些传入事件在NRD的GABA神经支配中有少量参与，并暗示在该核中存在固有的GABA能系统。放射自显像证实了这种局部神经支配，显示出纤维、轴突静脉曲张和在核尾部积聚3H - GABA的细胞体。
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引用次数: 0
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