Pub Date : 2024-03-01Epub Date: 2024-01-03DOI: 10.1007/s40572-023-00427-2
Logaraj Ramakreshnan, Nasrin Aghamohammadi
Purpose of review: Unprecedented urbanization in Asia affects the net radiation and energy flux of urban areas in the form of urban heat islands (UHI). The application of nature-based solutions (NbS) via urban green and blue infrastructures is a promising approach to mitigate UHI via urban boundary condition modifications, which affect the energy balance. This narrative review discusses the application of green and blue infrastructures in the Asian context by highlighting its progress, challenges, and recommendations. This review is descriptive in nature and includes perspectives on the discussed topics.
Recent findings: Studies on the application of green and blue infrastructures in UHI mitigation are still scant in Asia. Their cooling performance is greatly influenced by their types, size, geometry, surface roughness, spread (threshold distance), temporal scales, topography, pollution levels, prevailing climate, and assessment techniques. Distinct urban characteristics, climatic conditions, environmental risks, lack of awareness and expertise, lack of policy and government incentives, and limited scientific studies are the major challenges in their implementation of UHI mitigation in Asia. Although green and blue infrastructures are associated with urban cooling, more in-depth experimental work and multidisciplinary research collaboration are paramount to exploring its implementation potential in Asia and other countries that share similar urban and environmental characteristics.
{"title":"The Application of Nature-Based Solutions for Urban Heat Island Mitigation in Asia: Progress, Challenges, and Recommendations.","authors":"Logaraj Ramakreshnan, Nasrin Aghamohammadi","doi":"10.1007/s40572-023-00427-2","DOIUrl":"10.1007/s40572-023-00427-2","url":null,"abstract":"<p><strong>Purpose of review: </strong>Unprecedented urbanization in Asia affects the net radiation and energy flux of urban areas in the form of urban heat islands (UHI). The application of nature-based solutions (NbS) via urban green and blue infrastructures is a promising approach to mitigate UHI via urban boundary condition modifications, which affect the energy balance. This narrative review discusses the application of green and blue infrastructures in the Asian context by highlighting its progress, challenges, and recommendations. This review is descriptive in nature and includes perspectives on the discussed topics.</p><p><strong>Recent findings: </strong>Studies on the application of green and blue infrastructures in UHI mitigation are still scant in Asia. Their cooling performance is greatly influenced by their types, size, geometry, surface roughness, spread (threshold distance), temporal scales, topography, pollution levels, prevailing climate, and assessment techniques. Distinct urban characteristics, climatic conditions, environmental risks, lack of awareness and expertise, lack of policy and government incentives, and limited scientific studies are the major challenges in their implementation of UHI mitigation in Asia. Although green and blue infrastructures are associated with urban cooling, more in-depth experimental work and multidisciplinary research collaboration are paramount to exploring its implementation potential in Asia and other countries that share similar urban and environmental characteristics.</p>","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":" ","pages":"4-17"},"PeriodicalIF":7.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139086223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01Epub Date: 2023-11-14DOI: 10.1007/s40572-023-00418-3
Xin Ye, Hugo Lin
Purpose of review: This review aimed to systematically synthesize the global evidence base for natural disasters and human health using natural language processing (NLP) techniques.
Recent findings: We searched Embase, PubMed, Scopus, PsycInfo, and Web of Science Core Collection, using titles, abstracts, and keywords, and included only literature indexed in English. NLP techniques, including text classification, topic modeling, and geoparsing methods, were used to systematically identify and map scientific literature on natural disasters and human health published between January 1, 2012, and April 3, 2022. We predicted 6105 studies in the area of natural disasters and human health. Earthquakes, hurricanes, and tsunamis were the most frequent nature disasters; posttraumatic stress disorder (PTSD) and depression were the most frequently studied health outcomes; mental health services were the most common way of coping. Geographically, the evidence base was dominated by studies from high-income countries. Co-occurrence of natural disasters and psychological distress was common. Psychological distress was one of the top three most frequent topics in all continents except Africa, where infectious diseases was the most prevalent topic. Our findings demonstrated the importance and feasibility of using NLP to comprehensively map natural disasters and human health in the growing literature. The review identifies clear topics for future clinical and public health research and can provide an empirical basis for reducing the negative health effects of natural disasters.
综述目的:本综述旨在利用自然语言处理技术系统地综合全球自然灾害与人类健康的证据基础。最近的发现:我们检索了Embase、PubMed、Scopus、PsycInfo和Web of Science Core Collection,使用标题、摘要和关键字,并且只包括以英文索引的文献。采用自然语言处理技术,包括文本分类、主题建模和地质解析方法,系统地识别和绘制了2012年1月1日至2022年4月3日期间发表的关于自然灾害和人类健康的科学文献。我们预测在自然灾害和人类健康领域有6105项研究。地震、飓风和海啸是最常见的自然灾害;创伤后应激障碍(PTSD)和抑郁症是最常被研究的健康结果;心理健康服务是最常见的应对方式。从地理上看,证据基础主要是来自高收入国家的研究。自然灾害和心理困扰的共同发生是很常见的。心理困扰是除非洲以外各大洲最常见的三大话题之一,在非洲,传染病是最普遍的话题。我们的研究结果表明,在越来越多的文献中,使用NLP全面绘制自然灾害和人类健康地图的重要性和可行性。该审查确定了未来临床和公共卫生研究的明确主题,并可为减少自然灾害对健康的负面影响提供经验基础。
{"title":"Global Research on Natural Disasters and Human Health: a Mapping Study Using Natural Language Processing Techniques.","authors":"Xin Ye, Hugo Lin","doi":"10.1007/s40572-023-00418-3","DOIUrl":"10.1007/s40572-023-00418-3","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review aimed to systematically synthesize the global evidence base for natural disasters and human health using natural language processing (NLP) techniques.</p><p><strong>Recent findings: </strong>We searched Embase, PubMed, Scopus, PsycInfo, and Web of Science Core Collection, using titles, abstracts, and keywords, and included only literature indexed in English. NLP techniques, including text classification, topic modeling, and geoparsing methods, were used to systematically identify and map scientific literature on natural disasters and human health published between January 1, 2012, and April 3, 2022. We predicted 6105 studies in the area of natural disasters and human health. Earthquakes, hurricanes, and tsunamis were the most frequent nature disasters; posttraumatic stress disorder (PTSD) and depression were the most frequently studied health outcomes; mental health services were the most common way of coping. Geographically, the evidence base was dominated by studies from high-income countries. Co-occurrence of natural disasters and psychological distress was common. Psychological distress was one of the top three most frequent topics in all continents except Africa, where infectious diseases was the most prevalent topic. Our findings demonstrated the importance and feasibility of using NLP to comprehensively map natural disasters and human health in the growing literature. The review identifies clear topics for future clinical and public health research and can provide an empirical basis for reducing the negative health effects of natural disasters.</p>","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":" ","pages":"61-70"},"PeriodicalIF":7.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92153082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01Epub Date: 2023-12-01DOI: 10.1007/s40572-023-00420-9
Yiwen Zhang, Ye Tingting, Wenzhong Huang, Pei Yu, Gongbo Chen, Rongbin Xu, Jiangning Song, Yuming Guo, Shanshan Li
Purpose of review: Wildfire smoke is associated with human health, becoming an increasing public health concern. However, a comprehensive synthesis of the current evidence on the health impacts of ambient wildfire smoke on children and adolescents, an exceptionally vulnerable population, is lacking. We conduct a systematic review of peer-reviewed epidemiological studies on the association between wildfire smoke and health of children and adolescents.
Recent findings: We searched for studies available in MEDLINE, EMBASE, and Scopus from database inception up to October 11, 2022. Of 4926 studies initially identified, 59 studies from 14 countries were ultimately eligible. Over 33.3% of the studies were conducted in the USA, and two focused on multi-countries. The exposure assessment of wildfire smoke was heterogenous, with wildfire-specific particulate matters with diameters ≤ 2.5 µm (PM2.5, 22.0%) and all-source (22.0%) PM2.5 during wildfire period most frequently used. Over half of studies (50.6%) focused on respiratory-related morbidities/mortalities. Wildfire smoke exposure was consistently associated with enhanced risks of adverse health outcomes in children/adolescents. Meta-analysis results presented a pooled relative risk (RR) of 1.04 (95% confidence interval [CI], 0.96-1.12) for all-cause respiratory morbidity, 1.11 (95% Ci: 0.93-1.32) for asthma, 0.93 (95% CI, 0.85-1.03) for bronchitis, and 1.13 (95% CI, 1.05-1.23) for upper respiratory infection, whilst - 21.71 g for birth weight (95% CI, - 32.92 to - 10.50) per 10 µg/m3 increment in wildfire-specific PM2.5/all-source PM2.5 during wildfire event. The majority of studies found that wildfire smoke was associated with multiple adverse health outcomes among children and adolescents, with respiratory morbidities of significant concern. In-utero exposure to wildfire smoke may increase the risk of adverse birth outcomes and have long-term impacts on height. Higher maternal baseline exposure to wildfire smoke and poor family-level baseline birthweight respectively elevated risks in preterm birth and low birth weight associated with wildfire smoke. More studies in low- and middle-income countries and focusing on extremely young children are needed. Despite technological progress, wildfire smoke exposure measurements remain uncertain, demanding improved methodologies to have more precise assessment of wildfire smoke levels and thus quantify the corresponding health impacts and guide public mitigation actions.
{"title":"Health Impacts of Wildfire Smoke on Children and Adolescents: A Systematic Review and Meta-analysis.","authors":"Yiwen Zhang, Ye Tingting, Wenzhong Huang, Pei Yu, Gongbo Chen, Rongbin Xu, Jiangning Song, Yuming Guo, Shanshan Li","doi":"10.1007/s40572-023-00420-9","DOIUrl":"10.1007/s40572-023-00420-9","url":null,"abstract":"<p><strong>Purpose of review: </strong>Wildfire smoke is associated with human health, becoming an increasing public health concern. However, a comprehensive synthesis of the current evidence on the health impacts of ambient wildfire smoke on children and adolescents, an exceptionally vulnerable population, is lacking. We conduct a systematic review of peer-reviewed epidemiological studies on the association between wildfire smoke and health of children and adolescents.</p><p><strong>Recent findings: </strong>We searched for studies available in MEDLINE, EMBASE, and Scopus from database inception up to October 11, 2022. Of 4926 studies initially identified, 59 studies from 14 countries were ultimately eligible. Over 33.3% of the studies were conducted in the USA, and two focused on multi-countries. The exposure assessment of wildfire smoke was heterogenous, with wildfire-specific particulate matters with diameters ≤ 2.5 µm (PM<sub>2.5</sub>, 22.0%) and all-source (22.0%) PM<sub>2.5</sub> during wildfire period most frequently used. Over half of studies (50.6%) focused on respiratory-related morbidities/mortalities. Wildfire smoke exposure was consistently associated with enhanced risks of adverse health outcomes in children/adolescents. Meta-analysis results presented a pooled relative risk (RR) of 1.04 (95% confidence interval [CI], 0.96-1.12) for all-cause respiratory morbidity, 1.11 (95% Ci: 0.93-1.32) for asthma, 0.93 (95% CI, 0.85-1.03) for bronchitis, and 1.13 (95% CI, 1.05-1.23) for upper respiratory infection, whilst - 21.71 g for birth weight (95% CI, - 32.92 to - 10.50) per 10 µg/m<sup>3</sup> increment in wildfire-specific PM<sub>2.5</sub>/all-source PM<sub>2.5</sub> during wildfire event. The majority of studies found that wildfire smoke was associated with multiple adverse health outcomes among children and adolescents, with respiratory morbidities of significant concern. In-utero exposure to wildfire smoke may increase the risk of adverse birth outcomes and have long-term impacts on height. Higher maternal baseline exposure to wildfire smoke and poor family-level baseline birthweight respectively elevated risks in preterm birth and low birth weight associated with wildfire smoke. More studies in low- and middle-income countries and focusing on extremely young children are needed. Despite technological progress, wildfire smoke exposure measurements remain uncertain, demanding improved methodologies to have more precise assessment of wildfire smoke levels and thus quantify the corresponding health impacts and guide public mitigation actions.</p>","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":" ","pages":"46-60"},"PeriodicalIF":7.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138458398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-27DOI: 10.1007/s40572-023-00426-3
Kamran Abbasi, Parveen Ali, Virginia Barbour, Thomas Benfield, Kirsten Bibbins-Domingo, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Robert Mash, Peush Sahni, Wadeia Mohammad Sharief, Paul Yonga, Chris Zielinski
{"title":"Time to Treat the Climate and Nature Crisis as One Indivisible Global Health Emergency.","authors":"Kamran Abbasi, Parveen Ali, Virginia Barbour, Thomas Benfield, Kirsten Bibbins-Domingo, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Robert Mash, Peush Sahni, Wadeia Mohammad Sharief, Paul Yonga, Chris Zielinski","doi":"10.1007/s40572-023-00426-3","DOIUrl":"https://doi.org/10.1007/s40572-023-00426-3","url":null,"abstract":"","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":" ","pages":""},"PeriodicalIF":7.9,"publicationDate":"2024-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139570017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01Epub Date: 2023-11-30DOI: 10.1007/s40572-023-00423-6
Li-Hao Guo, Mohammed Zeeshan, Guo-Feng Huang, Duo-Hong Chen, Min Xie, Jun Liu, Guang-Hui Dong
Purpose of review: The increasing prevalence of cardiometabolic risk factors (CRFs) contributes to the rise in cardiovascular disease. Previous research has established a connection between air pollution and both the development and severity of CRFs. Given the ongoing impact of air pollution on human health, this review aims to summarize the latest research findings and provide an overview of the relationship between different types of air pollutants and CRFs.
Recent findings: CRFs include health conditions like diabetes, obesity, hypertension etc. Air pollution poses significant health risks and encompasses a wide range of pollutant types, air pollutants, such as particulate matter (PM), nitrogen dioxide (NO2), sulfur dioxide (SO2), and ozone (O2). More and more population epidemiological studies have shown a positive correlation between air pollution and CRFs. Although various pollutants have diverse effects on specific cellular molecular pathways, their main influence is on oxidative stress, inflammation response, and impairment of endothelial function. More and more studies have proved that air pollution can promote the occurrence and development of cardiovascular and metabolic risk factors, and the research on the relationship between air pollution and CRFs has grown intensively. An increasing number of studies are using new biological monitoring indicators to assess the occurrence and development of CRFs resulting from exposure to air pollution. Abnormalities in some important biomarkers in the population (such as homocysteine, uric acid, and C-reactive protein) caused by air pollution deserve more attention. Further research is warranted to more fully understand the link between air pollution and novel CRF biomarkers and to investigate potential prevention and interventions that leverage the mechanistic link between air pollution and CRFs.
{"title":"Influence of Air Pollution Exposures on Cardiometabolic Risk Factors: a Review.","authors":"Li-Hao Guo, Mohammed Zeeshan, Guo-Feng Huang, Duo-Hong Chen, Min Xie, Jun Liu, Guang-Hui Dong","doi":"10.1007/s40572-023-00423-6","DOIUrl":"10.1007/s40572-023-00423-6","url":null,"abstract":"<p><strong>Purpose of review: </strong>The increasing prevalence of cardiometabolic risk factors (CRFs) contributes to the rise in cardiovascular disease. Previous research has established a connection between air pollution and both the development and severity of CRFs. Given the ongoing impact of air pollution on human health, this review aims to summarize the latest research findings and provide an overview of the relationship between different types of air pollutants and CRFs.</p><p><strong>Recent findings: </strong>CRFs include health conditions like diabetes, obesity, hypertension etc. Air pollution poses significant health risks and encompasses a wide range of pollutant types, air pollutants, such as particulate matter (PM), nitrogen dioxide (NO<sub>2</sub>), sulfur dioxide (SO<sub>2</sub>), and ozone (O<sub>2</sub>). More and more population epidemiological studies have shown a positive correlation between air pollution and CRFs. Although various pollutants have diverse effects on specific cellular molecular pathways, their main influence is on oxidative stress, inflammation response, and impairment of endothelial function. More and more studies have proved that air pollution can promote the occurrence and development of cardiovascular and metabolic risk factors, and the research on the relationship between air pollution and CRFs has grown intensively. An increasing number of studies are using new biological monitoring indicators to assess the occurrence and development of CRFs resulting from exposure to air pollution. Abnormalities in some important biomarkers in the population (such as homocysteine, uric acid, and C-reactive protein) caused by air pollution deserve more attention. Further research is warranted to more fully understand the link between air pollution and novel CRF biomarkers and to investigate potential prevention and interventions that leverage the mechanistic link between air pollution and CRFs.</p>","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":" ","pages":"501-507"},"PeriodicalIF":7.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138458399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01DOI: 10.1007/s40572-023-00415-6
Fu-Shiuan Whitney Lee, Yu-Han Chen, Ngoc Dang Tran, Cheng-Kuan Lin, Le An Pham
Purpose of review: Occupational asbestos exposure has been extensively linked to various cancers, with ongoing debates regarding its association with kidney cancer. This study aims to investigate the correlation between occupational asbestos exposure and kidney cancer incidence. Additionally, potential influencing factors are analyzed to enhance the comprehension of the relationship between asbestos exposure and kidney cancer.
Recent finding: While asbestos has established strong associations with malignant mesothelioma and lung cancer, its connection to other malignancies such as gastric, colorectal, and kidney cancers remains under scrutiny. The current study presents mixed opinions on the relationship between asbestos exposure and kidney cancer. Our analysis revealed a potential association between asbestos exposure and the incidence of kidney cancer. Notably, among different types of asbestos, exposure to amphibole appeared to be particularly linked to a higher incident risk of kidney cancer.
{"title":"Association between Asbestos Exposure and the Incidence of Kidney Cancer: a Weight-of-Evidence Evaluation and Meta-analysis.","authors":"Fu-Shiuan Whitney Lee, Yu-Han Chen, Ngoc Dang Tran, Cheng-Kuan Lin, Le An Pham","doi":"10.1007/s40572-023-00415-6","DOIUrl":"10.1007/s40572-023-00415-6","url":null,"abstract":"<p><strong>Purpose of review: </strong>Occupational asbestos exposure has been extensively linked to various cancers, with ongoing debates regarding its association with kidney cancer. This study aims to investigate the correlation between occupational asbestos exposure and kidney cancer incidence. Additionally, potential influencing factors are analyzed to enhance the comprehension of the relationship between asbestos exposure and kidney cancer.</p><p><strong>Recent finding: </strong>While asbestos has established strong associations with malignant mesothelioma and lung cancer, its connection to other malignancies such as gastric, colorectal, and kidney cancers remains under scrutiny. The current study presents mixed opinions on the relationship between asbestos exposure and kidney cancer. Our analysis revealed a potential association between asbestos exposure and the incidence of kidney cancer. Notably, among different types of asbestos, exposure to amphibole appeared to be particularly linked to a higher incident risk of kidney cancer.</p>","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":" ","pages":"394-409"},"PeriodicalIF":7.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54228066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01Epub Date: 2023-09-28DOI: 10.1007/s40572-023-00411-w
Ami Shah, Rachel L Miller
Purpose of review: Prenatal and childhood exposure to synthetic chemicals, such as phenols and phthalates, have been linked to asthma and allergy, but the extent of this association and the underlying mechanisms are not fully understood. Here we provide an up-to-date review of the evidence linking phenol and phthalate exposure with childhood asthma and allergy and of proposed mechanistic pathways.
Recent findings: Five experimental and 12 epidemiological studies that examined associations between exposures to synthetic chemicals to asthma and allergic diseases were included. An additional 14 studies provided mechanistic support for the importance of immune modification through epigenetic regulation, induction of pro-allergic T2 expression, and endocrine disruption. While recent studies have provided further experimental and epidemiological evidence for how these chemical exposures may induce childhood asthma and allergy, the recent literature remains limited. However, emerging mechanistic studies have identified chemical-induced alterations in DNA methylation of genes implicated in allergic inflammation and endocrine disruption as potential pathways. In addition, barriers to decrease exposure to synthetic chemicals at the individual level (facilitated through education) and areas for further action at the organizational and governmental levels are suggested. The latter includes transferring some of the onus from the individual to organizations and legislation to restrict marketing and access to products containing potentially harmful chemicals and provide alternative products. We also suggest future research that focuses on further elucidating pathways between exposure to disease development and identifying strategies to reduce exposure at the population level.
{"title":"Synthetic Chemicals: What We Have Learned and Still Need to Learn About Their Associations with Childhood Allergy and Asthma.","authors":"Ami Shah, Rachel L Miller","doi":"10.1007/s40572-023-00411-w","DOIUrl":"10.1007/s40572-023-00411-w","url":null,"abstract":"<p><strong>Purpose of review: </strong>Prenatal and childhood exposure to synthetic chemicals, such as phenols and phthalates, have been linked to asthma and allergy, but the extent of this association and the underlying mechanisms are not fully understood. Here we provide an up-to-date review of the evidence linking phenol and phthalate exposure with childhood asthma and allergy and of proposed mechanistic pathways.</p><p><strong>Recent findings: </strong>Five experimental and 12 epidemiological studies that examined associations between exposures to synthetic chemicals to asthma and allergic diseases were included. An additional 14 studies provided mechanistic support for the importance of immune modification through epigenetic regulation, induction of pro-allergic T2 expression, and endocrine disruption. While recent studies have provided further experimental and epidemiological evidence for how these chemical exposures may induce childhood asthma and allergy, the recent literature remains limited. However, emerging mechanistic studies have identified chemical-induced alterations in DNA methylation of genes implicated in allergic inflammation and endocrine disruption as potential pathways. In addition, barriers to decrease exposure to synthetic chemicals at the individual level (facilitated through education) and areas for further action at the organizational and governmental levels are suggested. The latter includes transferring some of the onus from the individual to organizations and legislation to restrict marketing and access to products containing potentially harmful chemicals and provide alternative products. We also suggest future research that focuses on further elucidating pathways between exposure to disease development and identifying strategies to reduce exposure at the population level.</p>","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":" ","pages":"459-468"},"PeriodicalIF":7.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11836913/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41117464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01Epub Date: 2023-10-17DOI: 10.1007/s40572-023-00414-7
William Borchert, Stephanie T Grady, Jie Chen, Nicole V DeVille, Charlotte Roscoe, Futu Chen, Carol Mita, Isabel Holland, Grete E Wilt, Cindy R Hu, Unnati Mehta, Rachel C Nethery, Christine M Albert, Francine Laden, Jaime E Hart
Purpose of review: Environmental exposures have been associated with increased risk of cardiovascular mortality and acute coronary events, but their relationship with out-of-hospital cardiac arrest (OHCA) and sudden cardiac death (SCD) remains unclear. SCD is an important contributor to the global burden of cardiovascular disease worldwide.
Recent findings: Current literature suggests a relationship between environmental exposures and cardiovascular disease, but their relationship with OHCA/SCD remains unclear. A literature search was conducted in PubMed, Embase, Web of Science, and Global Health. Of 5138 studies identified by our literature search, this review included 30 studies on air pollution, 42 studies on temperature, 6 studies on both air pollution and temperature, and 1 study on altitude exposure and OHCA/SCD. Particulate matter air pollution, ozone, and both hot and cold temperatures are associated with increased risk of OHCA/SCD. Pollution and other exposures related to climate change play an important role in OHCA/SCD incidence.
综述目的:环境暴露与心血管死亡率和急性冠状动脉事件的风险增加有关,但它们与院外心脏骤停(OHCA)和心源性猝死(SCD)的关系尚不清楚。SCD是造成全球心血管疾病负担的重要因素。最近的发现:目前的文献表明环境暴露与心血管疾病之间存在关系,但它们与OHCA/SCD的关系尚不清楚。在PubMed、Embase、Web of Science和Global Health上进行了文献检索。在我们的文献检索确定的5138项研究中,这篇综述包括30项关于空气污染的研究,42项关于温度的研究,6项关于空气污染物和温度的研究以及1项关于海拔暴露和OHCA/SCD的研究。颗粒物空气污染、臭氧以及冷热温度都与OHCA/SCD风险增加有关。与气候变化有关的污染和其他暴露在OHCA/SCD发病率中起着重要作用。
{"title":"Air Pollution and Temperature: a Systematic Review of Ubiquitous Environmental Exposures and Sudden Cardiac Death.","authors":"William Borchert, Stephanie T Grady, Jie Chen, Nicole V DeVille, Charlotte Roscoe, Futu Chen, Carol Mita, Isabel Holland, Grete E Wilt, Cindy R Hu, Unnati Mehta, Rachel C Nethery, Christine M Albert, Francine Laden, Jaime E Hart","doi":"10.1007/s40572-023-00414-7","DOIUrl":"10.1007/s40572-023-00414-7","url":null,"abstract":"<p><strong>Purpose of review: </strong>Environmental exposures have been associated with increased risk of cardiovascular mortality and acute coronary events, but their relationship with out-of-hospital cardiac arrest (OHCA) and sudden cardiac death (SCD) remains unclear. SCD is an important contributor to the global burden of cardiovascular disease worldwide.</p><p><strong>Recent findings: </strong>Current literature suggests a relationship between environmental exposures and cardiovascular disease, but their relationship with OHCA/SCD remains unclear. A literature search was conducted in PubMed, Embase, Web of Science, and Global Health. Of 5138 studies identified by our literature search, this review included 30 studies on air pollution, 42 studies on temperature, 6 studies on both air pollution and temperature, and 1 study on altitude exposure and OHCA/SCD. Particulate matter air pollution, ozone, and both hot and cold temperatures are associated with increased risk of OHCA/SCD. Pollution and other exposures related to climate change play an important role in OHCA/SCD incidence.</p>","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":" ","pages":"490-500"},"PeriodicalIF":7.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11016309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41233011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01Epub Date: 2023-10-20DOI: 10.1007/s40572-023-00412-9
Federica Veneri, Inga Iamandii, Marco Vinceti, Linda S Birnbaum, Luigi Generali, Ugo Consolo, Tommaso Filippini
Purpose of review: We performed a systematic review and meta-analysis on the relation between fluoride exposure and skeletal fluorosis (SF) using a novel statistical methodology for dose-response modeling.
Recent findings: Skeletal fluorosis, a major health issue that is endemic in some regions, affects millions of people worldwide. However, data regarding the dose-response relation between fluoride exposure and SF are limited and outdated. We included twenty-three studies in the meta-analysis. When comparing the highest versus the lowest fluoride category, the summary risk ratio (RR) for SF prevalence was 2.05 (95% CI 1.60; 2.64), with a value of 2.73 (95% CI 1.92; 3.90) for drinking water and 1.40 (95% CI 0.90; 2.17) for urinary fluoride. The RR by the risk of bias (RoB) was 2.37 (95% CI 1.56; 3.58) and 1.78 (95% CI 1.34; 2.36) for moderate and high RoB studies, respectively. The dose-response curve based on a one-stage cubic spline regression model showed an almost linear positive relation between exposure and SF occurrence starting from relatively low concentrations up to 5 mg/L and 2.5 mg/L, respectively, for water and urinary fluoride, with no substantial increase above this threshold. The RR for developing moderate-severe forms increases at 5.00 mg/L and 2.5 mg/L of water and urinary fluoride, respectively. Better-quality studies are needed to confirm these results, but greater attention should be given to water fluoride levels to prevent SF, in addition to the other potential adverse effects of fluoride exposure.
{"title":"Fluoride Exposure and Skeletal Fluorosis: a Systematic Review and Dose-response Meta-analysis.","authors":"Federica Veneri, Inga Iamandii, Marco Vinceti, Linda S Birnbaum, Luigi Generali, Ugo Consolo, Tommaso Filippini","doi":"10.1007/s40572-023-00412-9","DOIUrl":"10.1007/s40572-023-00412-9","url":null,"abstract":"<p><strong>Purpose of review: </strong>We performed a systematic review and meta-analysis on the relation between fluoride exposure and skeletal fluorosis (SF) using a novel statistical methodology for dose-response modeling.</p><p><strong>Recent findings: </strong>Skeletal fluorosis, a major health issue that is endemic in some regions, affects millions of people worldwide. However, data regarding the dose-response relation between fluoride exposure and SF are limited and outdated. We included twenty-three studies in the meta-analysis. When comparing the highest versus the lowest fluoride category, the summary risk ratio (RR) for SF prevalence was 2.05 (95% CI 1.60; 2.64), with a value of 2.73 (95% CI 1.92; 3.90) for drinking water and 1.40 (95% CI 0.90; 2.17) for urinary fluoride. The RR by the risk of bias (RoB) was 2.37 (95% CI 1.56; 3.58) and 1.78 (95% CI 1.34; 2.36) for moderate and high RoB studies, respectively. The dose-response curve based on a one-stage cubic spline regression model showed an almost linear positive relation between exposure and SF occurrence starting from relatively low concentrations up to 5 mg/L and 2.5 mg/L, respectively, for water and urinary fluoride, with no substantial increase above this threshold. The RR for developing moderate-severe forms increases at 5.00 mg/L and 2.5 mg/L of water and urinary fluoride, respectively. Better-quality studies are needed to confirm these results, but greater attention should be given to water fluoride levels to prevent SF, in addition to the other potential adverse effects of fluoride exposure.</p>","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":" ","pages":"417-441"},"PeriodicalIF":7.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49675256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01DOI: 10.1007/s40572-023-00416-5
Juliana H Halbach, John M Cala, Samuel Y Paik, David M Zalk
Purpose of review: Control banding (CB) is a risk assessment strategy that has been applied globally to a variety of occupational hazards. This article describes how this method can be applied, recent developments in the CB literature, an example of how it is utilized for a large, diverse worksite, and where the future of CB is headed.
Recent findings: Over the past several years, the applications of CB have widened significantly and have accordingly helped bolster the public and occupational safety, health, and hygiene (OSHH) professionals' understanding of occupational exposure to various hazards. The fields of workplace chemicals, nanomaterials, and airborne pathogens (i.e., COVID-19), specifically have seen remarkable increases in the development of CB tools. Extensive CB tool validation efforts have also lent increasing credibility to this alternative approach. CB is a simplified strategy of assessing occupational exposures and providing commensurate controls and solutions to reduce workplace risks. CB can be used as a primary or tiered risk assessment and risk management approach which can be utilized by both OSHH professionals and nonexperts alike to identify solutions for reducing work-related exposures. The need for health and safety expertise will continue to grow as technological advancements, environmental changes, and economic forces increase workplace hazard complexity, and CB will continue to be a useful tool for those performing risk assessments.
{"title":"Control Banding and the Global Rise of Qualitative Risk Assessment Strategies.","authors":"Juliana H Halbach, John M Cala, Samuel Y Paik, David M Zalk","doi":"10.1007/s40572-023-00416-5","DOIUrl":"10.1007/s40572-023-00416-5","url":null,"abstract":"<p><strong>Purpose of review: </strong>Control banding (CB) is a risk assessment strategy that has been applied globally to a variety of occupational hazards. This article describes how this method can be applied, recent developments in the CB literature, an example of how it is utilized for a large, diverse worksite, and where the future of CB is headed.</p><p><strong>Recent findings: </strong>Over the past several years, the applications of CB have widened significantly and have accordingly helped bolster the public and occupational safety, health, and hygiene (OSHH) professionals' understanding of occupational exposure to various hazards. The fields of workplace chemicals, nanomaterials, and airborne pathogens (i.e., COVID-19), specifically have seen remarkable increases in the development of CB tools. Extensive CB tool validation efforts have also lent increasing credibility to this alternative approach. CB is a simplified strategy of assessing occupational exposures and providing commensurate controls and solutions to reduce workplace risks. CB can be used as a primary or tiered risk assessment and risk management approach which can be utilized by both OSHH professionals and nonexperts alike to identify solutions for reducing work-related exposures. The need for health and safety expertise will continue to grow as technological advancements, environmental changes, and economic forces increase workplace hazard complexity, and CB will continue to be a useful tool for those performing risk assessments.</p>","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":" ","pages":"410-416"},"PeriodicalIF":7.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54228067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}