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Prenatal Maternal Smoke, DNA Methylation, and Multi-omics of Tissues and Child Health 产前母亲吸烟,DNA甲基化和多组学组织和儿童健康
IF 7.9 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-06-07 DOI: 10.1007/s40572-022-00361-9
M. Cosín-Tomás, Ariadna Cilleros-Portet, Sofía Aguilar-Lacasaña, N. Fernández-Jiménez, M. Bustamante
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引用次数: 5
Methods for Evaluating Environmental Health Impacts at Different Stages of the Policy Process in Cities. 城市政策制定过程不同阶段的环境健康影响评估方法。
IF 7.4 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-06-01 Epub Date: 2022-04-07 DOI: 10.1007/s40572-022-00349-5
Jaime Benavides, Sebastian T Rowland, Jenni A Shearston, Yanelli Nunez, Darby W Jack, Marianthi-Anna Kioumourtzoglou

Purpose of review: Evaluating the environmental health impacts of urban policies is critical for developing and implementing policies that lead to more healthy and equitable cities. This article aims to (1) identify research questions commonly used when evaluating the health impacts of urban policies at different stages of the policy process, (2) describe commonly used methods, and (3) discuss challenges, opportunities, and future directions.

Recent findings: In the diagnosis and design stages of the policy process, research questions aim to characterize environmental problems affecting human health and to estimate the potential impacts of new policies. Simulation methods using existing exposure-response information to estimate health impacts predominate at these stages of the policy process. In subsequent stages, e.g., during implementation, research questions aim to understand the actual policy impacts. Simulation methods or observational methods, which rely on experimental data gathered in the study area to assess the effectiveness of the policy, can be applied at these stages. Increasingly, novel techniques fuse both simulation and observational methods to enhance the robustness of impact evaluations assessing implemented policies. The policy process consists of interdependent stages, from inception to end, but most reviewed studies focus on single stages, neglecting the continuity of the policy life cycle. Studies assessing the health impacts of policies using a multi-stage approach are lacking. Most studies investigate intended impacts of policies; focusing also on unintended impacts may provide a more comprehensive evaluation of policies.

审查目的:评估城市政策对环境健康的影响对于制定和实施能使城市更健康、更公平的政策至关重要。本文旨在:(1)确定在政策过程的不同阶段评估城市政策对健康的影响时常用的研究问题;(2)介绍常用的方法;(3)讨论挑战、机遇和未来方向:在政策过程的诊断和设计阶段,研究问题旨在确定影响人类健康的环境问题的特征,并估计新政策的潜在影响。在政策制定过程的这些阶段,使用现有暴露-反应信息来估计健康影响的模拟方法占主导地位。在随后的阶段,如实施过程中,研究问题旨在了解政策的实际影响。在这些阶段,可以采用模拟方法或观察方法,即依靠在研究区域收集的实验数据来评估政策的有效性。越来越多的新技术融合了模拟和观察方法,以提高对已实施政策的影响评估的稳健性。政策过程包括从开始到结束的各个相互依存的阶段,但大多数已审查的研究只关注单一阶段,而忽视了政策生命周期的连续性。缺乏采用多阶段方法评估政策对健康影响的研究。大多数研究调查了政策的预期影响;同时关注意外影响可能会提供更全面的政策评估。
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引用次数: 0
A Review of the Effectiveness of Current US Policies on Antimicrobial Use in Meat and Poultry Production. 美国现行肉类和家禽生产中抗菌剂使用政策的有效性审查》(A Review of the Effectiveness of Current US Policies on Anticrobial Use in Meat and Poultry Production)。
IF 7.4 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-06-01 Epub Date: 2022-04-27 DOI: 10.1007/s40572-022-00351-x
David Wallinga, Lidwien A M Smit, Meghan F Davis, Joan A Casey, Keeve E Nachman

Purpose: Industrial food animal production accounts for most animal-source protein consumed in the USA. These operations rely on an array of external inputs, which can include antimicrobials of medical importance. The use of these drugs in this context has been the subject of public health debate for decades because their widespread use contributes to the selection for and proliferation of drug-resistant bacteria and their genetic determinants. Here, we describe legislative and regulatory efforts, at different levels of governance in the USA, to curtail food animal consumption of medically important antimicrobials.

Recent findings: The features and relative success of the US efforts are examined alongside those of selected member states (Denmark and the Netherlands) of the European Union. Evaluation of efforts at all levels of US governance was complicated by shortcomings in prescribed data collection; nevertheless, available information suggests deficiencies in policy implementation and enforcement compromise the effectiveness of interventions pursued to date. The political will, robust systems for collecting and integrating data on antimicrobial consumption and use, and cross-sectoral collaboration that have been integral to the success of efforts in Denmark and The Netherlands have been notably absent in the USA, especially at the federal level.

目的:工业化食用动物生产占美国动物源蛋白质消费的绝大部分。这些生产依赖于一系列外部投入,其中可能包括具有重要医疗价值的抗菌药物。几十年来,在这种情况下使用这些药物一直是公共卫生辩论的主题,因为它们的广泛使用导致了耐药细菌及其基因决定因素的选择和扩散。在此,我们介绍了美国各级政府为减少食用动物对具有重要医疗意义的抗菌药物的消费而做出的立法和监管努力:最近的研究结果:我们将美国所做努力的特点和相对成功之处与欧盟部分成员国(丹麦和荷兰)所做的努力进行了对比研究。由于规定的数据收集工作存在缺陷,对美国各级治理工作的评估变得更加复杂;然而,现有信息表明,政策实施和执行方面的缺陷损害了迄今为止所采取的干预措施的有效性。丹麦和荷兰的成功离不开政治意愿、强大的抗菌药物消费和使用数据收集与整合系统以及跨部门合作,而美国,尤其是联邦层面,显然不具备这些条件。
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引用次数: 0
Air (ine)quality in the European Union. 欧盟的空气质量
IF 7.4 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-06-01 Epub Date: 2022-03-26 DOI: 10.1007/s40572-022-00348-6
Éloi Laurent

Purpose of review: This paper presents an analytical review of recent research on social inequality caused or compounded by ambient air pollution in the European Union.

Recent findings: While empirical studies have developed significantly both in the academic and institutional arena, they have largely focused on only one aspect: the exposure and sensitivity of individuals and groups to air pollution according to various criteria, documenting substantial and overlapping inequality. While EU policy should better address this proven impact inequality, research is also needed on new fronts of air (ine)quality (namely mental health impact and indoor air quality) as well as other types of ambient air inequality (such as inequality in responsibility and impact of air pollution mitigation policy).

综述目的:本文对欧盟近期关于环境空气污染造成或加剧社会不平等的研究进行了分析综述:虽然实证研究在学术和制度领域都有了长足的发展,但它们大多只关注一个方面:根据不同的标准,个人和群体对空气污染的暴露程度和敏感度,记录了大量重叠的不平等现象。虽然欧盟政策应更好地解决这种已被证实的影响不平等问题,但还需要对空气(低)质量的新方面(即心理健康影响和室内空气质量)以及其他类型的环境空气不平等问题(如责任不平等和空气污染减缓政策的影响)进行研究。
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引用次数: 0
A Review on Climate, Air Pollution, and Health in North Africa. 北非气候、空气污染与健康综述
IF 7.4 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-06-01 Epub Date: 2022-03-30 DOI: 10.1007/s40572-022-00350-y
Sekmoudi Imane, Bouakline Oumaima, Khomsi Kenza, Idrissi Laila, El Merabet Youssef, Souhaili Zineb, El Jarmouni Mohamed

Purpose of review: The aim of this review is to summarize and provide clear insights into studies that evaluate the interaction between air pollution, climate, and health in North Africa.

Recent findings: Few studies have estimated the effects of climate and air pollution on health in North Africa. Most of the studies highlighted the evidence of the link between climate and air pollution as driving factors and increased mortality and morbidity as health outcomes. Each North African country prioritized research on a specific health factor. It was observed that the health outcome from each driving factor depends on the studied area and data availability. The latter is a major challenge in the region. As such, more studies should be led in the future to cover more areas in North Africa and when more data are available. Data availability will help to explore the applicability of different tools and techniques new to the region. This review explores studies related to climate and air pollution, and their possible impacts on health in North Africa. On one hand, air quality studies have focused mainly on particulate matter exceedance levels and their long-term exposure impacts, namely, morbidity and mortality. The observed differences between the various studies are mainly due to the used exposure-response function, the studied population, background emissions, and natural emission from the Sahara Desert that characterize the region. On the other hand, climate studies have focused primarily on the impact of heat waves, vector-borne disease, and mental disorders. More than half of these studies have been on leishmaniasis disease. The review revealed unbalanced and insufficient research on health impacts from air pollution episodes and climate extremes across the region.

综述的目的:本综述的目的是总结和提供对评估北非空气污染、气候和健康之间相互作用的研究的明确见解。最近的发现:很少有研究估计气候和空气污染对北非健康的影响。大多数研究强调,有证据表明,气候和空气污染是驱动因素,死亡率和发病率上升是健康结果。每个北非国家都优先考虑对特定健康因素的研究。据观察,每个驱动因素的健康结果取决于研究区域和数据可用性。后者是该区域的一个重大挑战。因此,未来应该进行更多的研究,以覆盖北非的更多地区,并在有更多数据可用时进行研究。数据的可用性将有助于探索不同工具和技术对该区域的适用性。这篇综述探讨了与气候和空气污染有关的研究,以及它们对北非健康的可能影响。一方面,空气质量研究主要关注颗粒物超标水平及其长期暴露影响,即发病率和死亡率。不同研究之间观察到的差异主要是由于所使用的暴露反应函数、所研究的人口、背景排放和撒哈拉沙漠的自然排放,这些都是该地区的特征。另一方面,气候研究主要关注热浪、媒介传播疾病和精神障碍的影响。这些研究中有一半以上是关于利什曼病的。该审查显示,对该地区空气污染事件和极端气候对健康影响的研究不平衡且不足。
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引用次数: 0
Prenatal Diet as a Modifier of Environmental Risk Factors for Autism and Related Neurodevelopmental Outcomes. 产前饮食是自闭症和相关神经发育结局的环境危险因素的调节因素。
IF 7.9 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-06-01 DOI: 10.1007/s40572-022-00347-7
Megan Bragg, Jorge E Chavarro, Ghassan B Hamra, Jaime E Hart, Loni Philip Tabb, Marc G Weisskopf, Heather E Volk, Kristen Lyall

Purpose of review: Environmental chemicals and toxins have been associated with increased risk of impaired neurodevelopment and specific conditions like autism spectrum disorder (ASD). Prenatal diet is an individually modifiable factor that may alter associations with such environmental factors. The purpose of this review is to summarize studies examining prenatal dietary factors as potential modifiers of the relationship between environmental exposures and ASD or related neurodevelopmental outcomes.

Recent findings: Twelve studies were identified; five examined ASD diagnosis or ASD-related traits as the outcome (age at assessment range: 2-5 years) while the remainder addressed associations with neurodevelopmental scores (age at assessment range: 6 months to 6 years). Most studies focused on folic acid, prenatal vitamins, or omega-3 fatty acids as potentially beneficial effect modifiers. Environmental risk factors examined included air pollutants, endocrine disrupting chemicals, pesticides, and heavy metals. Most studies took place in North America. In 10/12 studies, the prenatal dietary factor under study was identified as a significant modifier, generally attenuating the association between the environmental exposure and ASD or neurodevelopment. Prenatal diet may be a promising target to mitigate adverse effects of environmental exposures on neurodevelopmental outcomes. Further research focused on joint effects is needed that encompasses a broader variety of dietary factors, guided by our understanding of mechanisms linking environmental exposures with neurodevelopment. Future studies should also aim to include diverse populations, utilize advanced methods to optimize detection of novel joint effects, incorporate consideration of timing, and consider both synergistic and antagonistic potential of diet.

综述目的:环境化学物质和毒素与神经发育受损和自闭症谱系障碍(ASD)等特定疾病的风险增加有关。产前饮食是一个个体可改变的因素,可能会改变与这些环境因素的关联。本综述的目的是总结产前饮食因素作为环境暴露与ASD或相关神经发育结局之间关系的潜在调节因素的研究。最近的发现:确定了12项研究;5项研究以ASD诊断或ASD相关特征作为结果(评估年龄范围:2-5岁),其余研究与神经发育评分的关系(评估年龄范围:6个月至6岁)。大多数研究集中在叶酸,产前维生素或omega-3脂肪酸作为潜在的有益效果调节剂。研究的环境风险因素包括空气污染物、干扰内分泌的化学物质、杀虫剂和重金属。大多数研究是在北美进行的。在10/12项研究中,产前饮食因素被确定为一个重要的修饰因素,通常会减弱环境暴露与ASD或神经发育之间的关联。产前饮食可能是一个有希望的目标,以减轻环境暴露对神经发育结果的不利影响。在我们对环境暴露与神经发育联系机制的理解的指导下,需要进一步研究包括更广泛的饮食因素在内的联合效应。未来的研究还应该包括不同的人群,利用先进的方法来优化检测新的联合效应,考虑时间,并考虑饮食的协同和拮抗潜力。
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引用次数: 9
Parental Occupational Exposure and Neurodevelopmental Disorders in Offspring: a Systematic Review and Meta-analysis 父母职业暴露与后代神经发育障碍的系统评价和荟萃分析
IF 7.9 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-05-06 DOI: 10.1007/s40572-022-00356-6
Maryam Bemanalizadeh, Mehri Khoshhali, Parvin Goli, I. Abdollahpour, R. Kelishadi
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引用次数: 3
Role of Climate Change in Changing Hepatic Health Maps 气候变化在肝脏健康图谱变化中的作用
IF 7.9 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-04-28 DOI: 10.1007/s40572-022-00352-w
A. Saad-Hussein, H. Ramadan, Ashraf Bareedy, Reda Elwakil
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引用次数: 3
Projecting the Impacts of a Changing Climate: Tropical Cyclones and Flooding 预测气候变化的影响:热带气旋和洪水
IF 7.9 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-04-11 DOI: 10.1007/s40572-022-00340-0
G. B. Anderson, A. Schumacher, J. Done, J. Hurrell
{"title":"Projecting the Impacts of a Changing Climate: Tropical Cyclones and Flooding","authors":"G. B. Anderson, A. Schumacher, J. Done, J. Hurrell","doi":"10.1007/s40572-022-00340-0","DOIUrl":"https://doi.org/10.1007/s40572-022-00340-0","url":null,"abstract":"","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":"9 1","pages":"244 - 262"},"PeriodicalIF":7.9,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42271543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Health Effects of Long-Term Exposure to Ambient PM2.5 in Asia-Pacific: a Systematic Review of Cohort Studies 亚太地区长期暴露于环境PM2.5对健康的影响:队列研究的系统回顾
IF 7.9 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-03-16 DOI: 10.1007/s40572-022-00344-w
Zhengyu Yang, Rahini Mahendran, P. Yu, R. Xu, Wenhua Yu, Sugeesha Godellawattage, Shanshan Li, Yuming Guo
{"title":"Health Effects of Long-Term Exposure to Ambient PM2.5 in Asia-Pacific: a Systematic Review of Cohort Studies","authors":"Zhengyu Yang, Rahini Mahendran, P. Yu, R. Xu, Wenhua Yu, Sugeesha Godellawattage, Shanshan Li, Yuming Guo","doi":"10.1007/s40572-022-00344-w","DOIUrl":"https://doi.org/10.1007/s40572-022-00344-w","url":null,"abstract":"","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":"9 1","pages":"130 - 151"},"PeriodicalIF":7.9,"publicationDate":"2022-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43670301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 23
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