S. Banu, Lakshmi Puzhankara, Madhurya N Kedlaya, J. Varghese, V. Ramanarayanan
Objectives The use of Sclerostin Antibody(Scl-Ab) as a bone anabolic agent has shown significant benefit in bone disorders in preclinical animal models and human clinical trials. Currently available evidence on the use of Scl-Ab in alveolar bone regeneration is limited to animal studies and hence this scoping review encompasses the animal studies conducted to ascertain the effectiveness of Scl-Ab on alveolar bone regeneration. Materials and methods The search strategy was aimed to locate published animal studies in which the treatment arm includes Sclerostin antibody administration for alveolar bone preservation or regeneration. The search terms used were (((Animal model) OR Rodent) AND Alveolar bone defect) AND Anti sclerostin antibody) OR Sclerostin antibody) AND Alveolar bone regeneration) OR Bone regeneration) AND Bone fill. Results Of the 559 results from Medline/PubMed, Scopus, Web of Science, Google scholar and additional articles from the references, six were included in the review. Scl-Ab was found to be effective in improving the bone quality and quantity. It was also observed that Scl-Ab was useful in reduced bone density associated with diseases and conditiona affecting osteoblast activity. Conclusion The review concluded that Scl-Ab promotes alveolar bone augmentation and improves bone quality without surgical interventions.
目的在临床前动物模型和人类临床试验中,使用硬化蛋白抗体(Scl-Ab)作为骨合成代谢剂对骨疾病具有显著的益处。目前可用的关于Scl-Ab在牙槽骨再生中的应用的证据仅限于动物研究,因此本范围综述包括为确定Scl-Abs对牙槽骨再生的有效性而进行的动物研究。材料和方法搜索策略旨在定位已发表的动物研究,其中治疗组包括用于牙槽骨保存或再生的硬化蛋白抗体给药。使用的搜索词是(((动物模型)或啮齿动物)和牙槽骨缺损)和抗硬化蛋白抗体)或硬化蛋白抗体(和牙槽骨再生)或骨再生)和骨填充。结果在Medline/PubMed、Scopus、Web Of Science、Google scholar和参考文献中的559篇结果中,有6篇被纳入综述。Scl-Ab能有效地改善骨的质量和数量。还观察到Scl-Ab可用于降低与影响成骨细胞活性的疾病和条件相关的骨密度。结论Scl-Ab促进牙槽骨增大,改善骨质量,无需手术干预。
{"title":"Is sclerostin antibody an effective agent for alveolar bone regeneration in animal models? A scoping review","authors":"S. Banu, Lakshmi Puzhankara, Madhurya N Kedlaya, J. Varghese, V. Ramanarayanan","doi":"10.7126/cumudj.1110413","DOIUrl":"https://doi.org/10.7126/cumudj.1110413","url":null,"abstract":"Objectives \u0000The use of Sclerostin Antibody(Scl-Ab) as a bone anabolic agent has shown significant benefit in bone disorders in preclinical animal models and human clinical trials. Currently available evidence on the use of Scl-Ab in alveolar bone regeneration is limited to animal studies and hence this scoping review encompasses the animal studies conducted to ascertain the effectiveness of Scl-Ab on alveolar bone regeneration. \u0000Materials and methods \u0000The search strategy was aimed to locate published animal studies in which the treatment arm includes Sclerostin antibody administration for alveolar bone preservation or regeneration. The search terms used were (((Animal model) OR Rodent) AND Alveolar bone defect) AND Anti sclerostin antibody) OR Sclerostin antibody) AND Alveolar bone regeneration) OR Bone regeneration) AND Bone fill. \u0000Results \u0000Of the 559 results from Medline/PubMed, Scopus, Web of Science, Google scholar and additional articles from the references, six were included in the review. Scl-Ab was found to be effective in improving the bone quality and quantity. It was also observed that Scl-Ab was useful in reduced bone density associated with diseases and conditiona affecting osteoblast activity. \u0000Conclusion \u0000 The review concluded that Scl-Ab promotes alveolar bone augmentation and improves bone quality without surgical interventions.","PeriodicalId":10781,"journal":{"name":"Cumhuriyet Dental Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49099729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: The aim of this study was to evaluate the structural microporosity (MP) and marginal gap (MG) of different flowable composite resins placed with different instruments using micro-computed tomography (μCT). Materials and Methods: Standard Class II MOD cavities were prepared on 108 lower third molar teeth. Three different flowable composite resins; Filtek Bulk-fill, SDR Bulk-fill and I-Flow conventional flowable composite resin were applied to the cavities using a sharp explorer, a microbrush or an injector. After they were covered with a paste-like nanohybrid composite resin, μCT images were examined in terms of MP and MG. Statistical analysis of the data was performed using two-way ANOVA and Tukey’s post hoc tests. Results: MP was observed less in explorer group than microbrush and injector groups (p < 0.05). There was no significant difference between microbrush and injector groups (p > 0.05). i-FLOW flowable composite resin showed the highest MP rate compared to the other two groups (p < 0.05). There was no significant difference between SDR and Filtek Bulk-fill in MP (p > 0.05). In terms of MG, i-FLOW presented higher MG values than other two materials (p < 0.05), while the instruments showed similar results (p > 0.05). Conclusions: Additional occluso-gingivally vibration of flowable materials with an explorer may be useful in the placement. Bulk-fill composite resins are better than conventional flowable composite resin in terms of MP and MG.
{"title":"Micro-computed tomography assesment of structural microporosity and marginal gaps in different flowable composites placed with different instruments","authors":"S. Demirbuğa, H. Balkaya, Ebru Nur Uçar, B. Avci","doi":"10.7126/cumudj.1115117","DOIUrl":"https://doi.org/10.7126/cumudj.1115117","url":null,"abstract":"Objectives: The aim of this study was to evaluate the structural microporosity (MP) and marginal gap (MG) of different flowable composite resins placed with different instruments using micro-computed tomography (μCT). \u0000Materials and Methods: Standard Class II MOD cavities were prepared on 108 lower third molar teeth. Three different flowable composite resins; Filtek Bulk-fill, SDR Bulk-fill and I-Flow conventional flowable composite resin were applied to the cavities using a sharp explorer, a microbrush or an injector. After they were covered with a paste-like nanohybrid composite resin, μCT images were examined in terms of MP and MG. Statistical analysis of the data was performed using two-way ANOVA and Tukey’s post hoc tests. \u0000Results: MP was observed less in explorer group than microbrush and injector groups (p < 0.05). There was no significant difference between microbrush and injector groups (p > 0.05). i-FLOW flowable composite resin showed the highest MP rate compared to the other two groups (p < 0.05). There was no significant difference between SDR and Filtek Bulk-fill in MP (p > 0.05). In terms of MG, i-FLOW presented higher MG values than other two materials (p < 0.05), while the instruments showed similar results (p > 0.05). \u0000Conclusions: Additional occluso-gingivally vibration of flowable materials with an explorer may be useful in the placement. Bulk-fill composite resins are better than conventional flowable composite resin in terms of MP and MG.","PeriodicalId":10781,"journal":{"name":"Cumhuriyet Dental Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44033150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The aim of this study was to examine the effect of photodynamic therapy (PDT) using toluidine blue O (TBO), curcumin (CUR) and methylene blue (MB) photosensitizers on root canal dentin microhardness by comparing it with sodium hypochlorite (NaOCl) + ethylenediamine tetraacetic acid (EDTA). Materials and methods: The root canals of 100 human premolar teeth were shaped by the R25 file (Reciproc; VDW, Munich, Germany). The working length of the teeth was determined by using a #10 K-file, keeping it 1mm shorter than the tooth apex. The R25 file was used to prepare the root canals. After every three pecking motions, irrigation was performed and a total of 10 mm of distilled water was used. The specimens were randomly distributed according to the disinfection method; NaOCl+EDTA, PDT with TBO, PDT with CUR, PDT with MB and distilled water (DS) (n=20). Grooves were prepared on the buccal and lingual surfaces of the prepared teeth, parallel to the long axis of the tooth, without touching the root canals. The roots were divided into two parts by means of a cement spatula placed in these grooves. Root canal dentin microhardness was evaluated by the Vickers test method. Three measurements were made by applying 300 g of force for 15 seconds and the average was calculated. It was recorded as the Vickers hardness value. The data were analyzed by using the one-way ANOVA and Dunnett’s post hoc tests (α=0.05). Results: All photosensitizer groups showed significantly higher microhardness value than the groups of DS and NaOCl + EDTA (p0.05). Conclusions: PDT with CUR obtained the highest radicular dentin microhardness.
{"title":"The Effect of Photodynamic Therapy Applied with Different Photosensitizers on Dentin Hardness in Comparison with Conventional Irrigation","authors":"Cihan Küden","doi":"10.7126/cumudj.1199515","DOIUrl":"https://doi.org/10.7126/cumudj.1199515","url":null,"abstract":"Objective: The aim of this study was to examine the effect of photodynamic therapy (PDT) using toluidine blue O (TBO), curcumin (CUR) and methylene blue (MB) photosensitizers on root canal dentin microhardness by comparing it with sodium hypochlorite (NaOCl) + ethylenediamine tetraacetic acid (EDTA). \u0000Materials and methods: The root canals of 100 human premolar teeth were shaped by the R25 file (Reciproc; VDW, Munich, Germany). The working length of the teeth was determined by using a #10 K-file, keeping it 1mm shorter than the tooth apex. The R25 file was used to prepare the root canals. After every three pecking motions, irrigation was performed and a total of 10 mm of distilled water was used. The specimens were randomly distributed according to the disinfection method; NaOCl+EDTA, PDT with TBO, PDT with CUR, PDT with MB and distilled water (DS) (n=20). Grooves were prepared on the buccal and lingual surfaces of the prepared teeth, parallel to the long axis of the tooth, without touching the root canals. The roots were divided into two parts by means of a cement spatula placed in these grooves. Root canal dentin microhardness was evaluated by the Vickers test method. Three measurements were made by applying 300 g of force for 15 seconds and the average was calculated. It was recorded as the Vickers hardness value. The data were analyzed by using the one-way ANOVA and Dunnett’s post hoc tests (α=0.05). \u0000Results: All photosensitizer groups showed significantly higher microhardness value than the groups of DS and NaOCl + EDTA (p0.05). \u0000Conclusions: PDT with CUR obtained the highest radicular dentin microhardness.","PeriodicalId":10781,"journal":{"name":"Cumhuriyet Dental Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41661262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: The aim of this study was to evaluate the antimicrobial efficacy of Potassium Titanium Phosphate (KTP) laser-activated irrigation solutions on intraradicular Enterococcus faecalis biofilms in invitro conditions by using a scanning electron microscope. Materials and Methods: 120 single-root, single canal permanent mandibular premolar human teeth were used. Sterilization and disinfection of the teeth were performed. E. faecalis biofilms were obtained after 4 weeks by re-inoculation procedures. Each group was divided into 6 groups consisting of 20 roots and root canal disinfection protocols were applied using irrigation solutions with 5.25% NaOCl, saline, super-oxidized water solution, 8ppm ozonated water, 2% CHX, 17% EDTA, all activated by KTP laser. It was smear-planted to a solid medium which split as before and after the disinfection applications for the aim of Counting Microorganism colonies from root canals and data were evaluated statistically. In this statistical evaluation one way ANOVA and Tukey tests were used. Before and after the irrigation procedures for presence and elimination of biofilm the root canals were processed for scanning electron microscopy and biofilm was examined on the standard images. Results: As a result of the statistical comparison performed among all groups, while NaOCl ensures the highest amount of elimination as a positive control group, the lowest amount of bacterial elimination was detected in the SF group that applied as the negative control group (P0,05), EDTA showed the lowest antibiofilm effect (P
{"title":"Antibiofilm Effect of Different Irrigation Solutions Activated with KTP Laser","authors":"Zuhal Elmali, R. Zan","doi":"10.7126/cumudj.1205797","DOIUrl":"https://doi.org/10.7126/cumudj.1205797","url":null,"abstract":"Objectives: The aim of this study was to evaluate the antimicrobial efficacy of Potassium Titanium Phosphate (KTP) laser-activated irrigation solutions on intraradicular Enterococcus faecalis biofilms in invitro conditions by using a scanning electron microscope. \u0000Materials and Methods: 120 single-root, single canal permanent mandibular premolar human teeth were used. Sterilization and disinfection of the teeth were performed. E. faecalis biofilms were obtained after 4 weeks by re-inoculation procedures. Each group was divided into 6 groups consisting of 20 roots and root canal disinfection protocols were applied using irrigation solutions with 5.25% NaOCl, saline, super-oxidized water solution, 8ppm ozonated water, 2% CHX, 17% EDTA, all activated by KTP laser. It was smear-planted to a solid medium which split as before and after the disinfection applications for the aim of Counting Microorganism colonies from root canals and data were evaluated statistically. In this statistical evaluation one way ANOVA and Tukey tests were used. Before and after the irrigation procedures for presence and elimination of biofilm the root canals were processed for scanning electron microscopy and biofilm was examined on the standard images. \u0000Results: As a result of the statistical comparison performed among all groups, while NaOCl ensures the highest amount of elimination as a positive control group, the lowest amount of bacterial elimination was detected in the SF group that applied as the negative control group (P0,05), EDTA showed the lowest antibiofilm effect (P","PeriodicalId":10781,"journal":{"name":"Cumhuriyet Dental Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48398425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: The aim of this study was to compare the simulated canal shaping efficiencies of five different NiTi rotary file systems. Materials and Methods: In the study, 100 transparent resin blocks with J-shaped canals were randomly divided into five groups (n=20). Simulated canals were shaped with VDW.Rotate (VR), TruNatomy (TRN), HyFlex CM (HF), EdgeFile X7 (EF), or ProTaper Next (PTN) files. Ten measuring points were detected on the pre- and post-preparation images taken from the blocks and superimposed. After preparation, the total canal width and the amount of transportation were calculated for the determined measuring levels. Zipping and ledge formation, instrument fracture and deformation, and change in working length were evaluated. The data were statistically analyzed with the Kolmogorov-Smirnov test, one-way ANOVA, Tukey test, Chi-Square test, and a Monte Carlo version of the Fisher Exact tests. The error level was taken as 0.05. Results: There were significant differences between the groups at all measuring levels in terms of total canal width after instrumentation (p = 0.001). Significant differences in the amount of transportation were found between the groups (p = 0.001) except at levels 4 (p = 0.169) and 10 (p = 0.054). Zip and instrument fractures did not occur in any group. 3 EF size 25/.04 files were deformed (p = 0.021). There was no significant difference between the groups in terms of ledge formation and working length change (p > 0.05). Conclusions: According to findings obtained in the study, transportation occurred at all 10 measuring levels with all file systems used. HF and EF systems were found to be more reliable in terms of transportation in the middle and coronal regions. Wider canal preparation was obtained with the PTN system in the middle and coronal regions.
{"title":"Comparative Evaluation of the Shaping Ability of Five Different Nickel-Titanium Rotary File Systems in Simulated Canals","authors":"Ö. Bilgin, D. Altunbaş","doi":"10.7126/cumudj.1204170","DOIUrl":"https://doi.org/10.7126/cumudj.1204170","url":null,"abstract":"Objectives: The aim of this study was to compare the simulated canal shaping efficiencies of five different NiTi rotary file systems. \u0000Materials and Methods: In the study, 100 transparent resin blocks with J-shaped canals were randomly divided into five groups (n=20). Simulated canals were shaped with VDW.Rotate (VR), TruNatomy (TRN), HyFlex CM (HF), EdgeFile X7 (EF), or ProTaper Next (PTN) files. Ten measuring points were detected on the pre- and post-preparation images taken from the blocks and superimposed. After preparation, the total canal width and the amount of transportation were calculated for the determined measuring levels. Zipping and ledge formation, instrument fracture and deformation, and change in working length were evaluated. The data were statistically analyzed with the Kolmogorov-Smirnov test, one-way ANOVA, Tukey test, Chi-Square test, and a Monte Carlo version of the Fisher Exact tests. The error level was taken as 0.05. \u0000Results: There were significant differences between the groups at all measuring levels in terms of total canal width after instrumentation (p = 0.001). Significant differences in the amount of transportation were found between the groups (p = 0.001) except at levels 4 (p = 0.169) and 10 (p = 0.054). Zip and instrument fractures did not occur in any group. 3 EF size 25/.04 files were deformed (p = 0.021). There was no significant difference between the groups in terms of ledge formation and working length change (p > 0.05). \u0000Conclusions: According to findings obtained in the study, transportation occurred at all 10 measuring levels with all file systems used. HF and EF systems were found to be more reliable in terms of transportation in the middle and coronal regions. Wider canal preparation was obtained with the PTN system in the middle and coronal regions.","PeriodicalId":10781,"journal":{"name":"Cumhuriyet Dental Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42753897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Akif Demirel, T. Bezgin, N. Bağiş, Ş. Sarı, F. Akaltan
Abstract Objectives: The novel coronavirus pandemic has become a real challenge for provision of dental education. The aim of this survey study was to evaluate the opinions of dental faculty educators and students about online education after e-learning experience. Materials and Methods: The research was conducted on educators and 4th and 5th grade students at XXXXX University, Faculty of Dentistry. Questionnaire items for educators and students were categorized into the following factors: educators’/students’ personal and professional skills and attitudes towards online education, online theoretical education, online practical training, online exams, handling and quality of education during pandemic. The data obtained was recorded as percentage (%) and interpreted. Results: 52 (73%) educators participated in this survey study. 50% of them said online courses were not as successful as face-to-face learning. Moreover, 40% of the educators stated that shortened class times were not sufficient to convey the course content. 74% of the participants expressed belief that online exams do not properly gauge students’ lesson comprehension. In addition, 281 students (75%) participated in this survey study. 32% of the students stated that they easily adapted to online education conditions. However, 84% of the students stated that they do not think that online education increased their clinical skills. Conclusions: The results of this study showed that academicians hold a negative view of distance learning as they think online theoretical courses, practical training and exams impaired the quality of learning. On the other hand, dentistry students have a positive attitude towards online theoretical education but are concerned about clinical skill acquisition.
{"title":"Perspectives of Students and Educators on the Effects of the COVID-19 Pandemic on Undergraduate Dental Education","authors":"Akif Demirel, T. Bezgin, N. Bağiş, Ş. Sarı, F. Akaltan","doi":"10.7126/cumudj.1199844","DOIUrl":"https://doi.org/10.7126/cumudj.1199844","url":null,"abstract":"Abstract \u0000Objectives: The novel coronavirus pandemic has become a real challenge for provision of dental education. The aim of this survey study was to evaluate the opinions of dental faculty educators and students about online education after e-learning experience. \u0000Materials and Methods: The research was conducted on educators and 4th and 5th grade students at XXXXX University, Faculty of Dentistry. Questionnaire items for educators and students were categorized into the following factors: educators’/students’ personal and professional skills and attitudes towards online education, online theoretical education, online practical training, online exams, handling and quality of education during pandemic. The data obtained was recorded as percentage (%) and interpreted. \u0000Results: 52 (73%) educators participated in this survey study. 50% of them said online courses were not as successful as face-to-face learning. Moreover, 40% of the educators stated that shortened class times were not sufficient to convey the course content. 74% of the participants expressed belief that online exams do not properly gauge students’ lesson comprehension. In addition, 281 students (75%) participated in this survey study. 32% of the students stated that they easily adapted to online education conditions. However, 84% of the students stated that they do not think that online education increased their clinical skills. \u0000Conclusions: The results of this study showed that academicians hold a negative view of distance learning as they think online theoretical courses, practical training and exams impaired the quality of learning. On the other hand, dentistry students have a positive attitude towards online theoretical education but are concerned about clinical skill acquisition.","PeriodicalId":10781,"journal":{"name":"Cumhuriyet Dental Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47393664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Early childhood caries (ECC) is a pathologic condition of multifactorial nature. The diagnosis of the same has been limited to clinical and radiographic aids with very little significance to assess its inflammatory component. objectives: The present study aims to evaluate the role of leptin, an adipocytokine as a non-invasive inflammatory biomarker in ECC. Materials and Method: A total of 60 children between the age of (3-5) years were selected for the study. The study subjects were divided into three groups of 20 each including Group 1 as control, Group 2 with mild to moderate ECC and Group 3 with severe ECC. Saliva samples were taken from all subjects and collected again after 2 months following rehabilitative intervention. Levels of salivary leptin were determined using Enzyme-Linked Immunosorbent Assay (ELISA). Results: Levels of salivary leptin were significantly associated with severity of dental caries. The intragroup comparisons of pre and post treatment levels of salivary leptin showed significant reductions in both mild to moderate ECC and severe ECC groups following caries control. Inter group evaluation between mild to moderate ECC and severe ECC post treatment showed statistically significant decline of leptin levels in comparison to baseline values. Conclusion: There was a statistically significant decline in salivary leptin levels between the mild moderate and severe ECC group, after 2 months following caries control. Thus, leptin holds a potential to be recognized as a reliable future prognostic and diagnostic inflammatory marker in early childhood caries.
{"title":"“ESTIMATION OF SALIVARY LEPTIN LEVELS IN CHILDREN WITH EARLY CHILDHOOD CARIES – AN INTERVENTIONAL STUDY”","authors":"Pratima R. Mokashi, S. Bhandary","doi":"10.7126/cumudj.1100449","DOIUrl":"https://doi.org/10.7126/cumudj.1100449","url":null,"abstract":"Background: Early childhood caries (ECC) is a pathologic condition of multifactorial nature. The diagnosis of the same has been limited to clinical and radiographic aids with very little significance to assess its inflammatory component. objectives: The present study aims to evaluate the role of leptin, an adipocytokine as a non-invasive inflammatory biomarker in ECC. \u0000Materials and Method: A total of 60 children between the age of (3-5) years were selected for the study. The study subjects were divided into three groups of 20 each including Group 1 as control, Group 2 with mild to moderate ECC and Group 3 with severe ECC. Saliva samples were taken from all subjects and collected again after 2 months following rehabilitative intervention. Levels of salivary leptin were determined using Enzyme-Linked Immunosorbent Assay (ELISA). \u0000Results: Levels of salivary leptin were significantly associated with severity of dental caries. The intragroup comparisons of pre and post treatment levels of salivary leptin showed significant reductions in both mild to moderate ECC and severe ECC groups following caries control. Inter group evaluation between mild to moderate ECC and severe ECC post treatment showed statistically significant decline of leptin levels in comparison to baseline values. \u0000Conclusion: There was a statistically significant decline in salivary leptin levels between the mild moderate and severe ECC group, after 2 months following caries control. Thus, leptin holds a potential to be recognized as a reliable future prognostic and diagnostic inflammatory marker in early childhood caries.","PeriodicalId":10781,"journal":{"name":"Cumhuriyet Dental Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44484868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: Cysts seen in the jaws may be odontogenic or non-odontogenic, depending on the tissue of origin. Although there are different methods to diagnose these lesions, histopathological examination of tissue biopsy of the lesion is accepted as the 'gold standard' in cases where the diagnosis is insufficient. Although there are different methods to diagnose these lesions, histopathological examination of tissue biopsy of the lesion is accepted as the 'gold standard' in cases where the diagnosis is insufficient. Materials and Methods: Pathology results of 436 patients who applied to Zonguldak Bülent Ecevit University Faculty of Dentistry, Oral and Maxillofacial Radiology Clinic between 2016-2021 for any reason and underwent biopsy were retrospectively scanned using digital archives. While classifying the cyst, the criteria published by the World Health Organization (WHO) in 2017 were taken into account. Obtained results were recorded for statistical analysis. SPSS 22.0 Software Package Program (SPSS 22.0 Software Package Program, Inc. Chicago, IL, USA) was used as statistical software in the study. Results: Of the 436 patients included in the study, 250 (57.3%) were male and 186 (42.7%) were female. The ages of the patients ranged between 7 and 82 years, and the mean age of the patients was 35.5±15.8. As a result of the findings, it was determined that the most common cysts were radicular cysts (53.7%). Radicular cysts were most commonly located in the posterior mandible and anterior maxilla anatomically. Conclusions: In addition to clinical and radiological examination, histopathological examination of biopsy samples taken from tissues is of great importance in the correct diagnosis and treatment planning of jaw cysts.
目的:颌骨囊肿可能是牙源性的,也可能是非牙源性的,这取决于其起源组织。虽然诊断这些病变有不同的方法,但在诊断不充分的情况下,病变组织活检的组织病理学检查被认为是“金标准”。虽然诊断这些病变有不同的方法,但在诊断不充分的情况下,病变组织活检的组织病理学检查被认为是“金标准”。材料与方法:对2016-2021年期间因任何原因就诊于伦特埃杰维特大学牙科、口腔颌面放射学诊所并行活检的436例患者的病理结果进行回顾性扫描。在对囊肿进行分类时,考虑了世界卫生组织(WHO) 2017年发布的标准。记录所得结果进行统计分析。SPSS 22.0软件包程序公司(SPSS 22.0软件包程序公司)Chicago, IL, USA)作为本研究的统计软件。结果:纳入研究的436例患者中,男性250例(57.3%),女性186例(42.7%)。患者年龄7 ~ 82岁,平均年龄35.5±15.8岁。结果表明,最常见的囊肿为根性囊肿(53.7%)。根状囊肿在解剖学上最常见于下颌骨后缘和上颌骨前缘。结论:除临床和影像学检查外,组织活检标本的组织病理学检查对颌骨囊肿的正确诊断和治疗方案具有重要意义。
{"title":"Jaw Cysts: A Retrospective Study in a Turkish Subpopulation","authors":"Emre Haylaz, G. Geduk, Ç. Şeker, M. İçen","doi":"10.7126/cumudj.1184217","DOIUrl":"https://doi.org/10.7126/cumudj.1184217","url":null,"abstract":"Objectives: Cysts seen in the jaws may be odontogenic or non-odontogenic, depending on the tissue of origin. Although there are different methods to diagnose these lesions, histopathological examination of tissue biopsy of the lesion is accepted as the 'gold standard' in cases where the diagnosis is insufficient. Although there are different methods to diagnose these lesions, histopathological examination of tissue biopsy of the lesion is accepted as the 'gold standard' in cases where the diagnosis is insufficient. \u0000Materials and Methods: Pathology results of 436 patients who applied to Zonguldak Bülent Ecevit University Faculty of Dentistry, Oral and Maxillofacial Radiology Clinic between 2016-2021 for any reason and underwent biopsy were retrospectively scanned using digital archives. While classifying the cyst, the criteria published by the World Health Organization (WHO) in 2017 were taken into account. Obtained results were recorded for statistical analysis. SPSS 22.0 Software Package Program (SPSS 22.0 Software Package Program, Inc. Chicago, IL, USA) was used as statistical software in the study. \u0000Results: Of the 436 patients included in the study, 250 (57.3%) were male and 186 (42.7%) were female. The ages of the patients ranged between 7 and 82 years, and the mean age of the patients was 35.5±15.8. As a result of the findings, it was determined that the most common cysts were radicular cysts (53.7%). Radicular cysts were most commonly located in the posterior mandible and anterior maxilla anatomically. \u0000Conclusions: In addition to clinical and radiological examination, histopathological examination of biopsy samples taken from tissues is of great importance in the correct diagnosis and treatment planning of jaw cysts.","PeriodicalId":10781,"journal":{"name":"Cumhuriyet Dental Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42203642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: To provide pediatric nurses with knowledge and skills on oral and dental health and to increase their awareness. Material and Methods: In the first phase of the study, pre-tests were given to pediatric nurses in Trabzon and Rize central and district hospitals. A Whatsapp group was created with the nurses who completed the tests, and the training video prepared by the researcher was shared. In the second phase of the study, the same questions were applied again as the post-test. Jamovi (Version 1.0.4) software was used for statistical analysis. P < 0.05 was accepted as statistically significant in all analyses. Results: Of the 91 nurses who completed both the pre-test and the post-test, 83 (91.2%) were female and 8 (8.8%) were male. In all sections in the test category consisting of six different sections (Tooth Decay, Risk Factors in Dental Caries, Prevention of Dental Caries, Oral and Dental Injuries, Children with Special Care Needs, What to Do - How to do?), the success rate was significantly higher in the post-test ( p < 0.001). Conclusion: Research emphasizes that neonatal nurses, pediatric nurses and health professionals working in community health centers should be activated and empowered in order to prevent oral and dental health problems of children, and awareness should be increased with scientifically valid educational guidelines. The results of the present study support these views and emphasize the importance of education by showing significant improvement with the training provided to nurses who had insufficient knowledge and awareness about the subject. Amaç: Pediatri hemşirelerine ağız ve diş sağlığı konusundaki bilgi ve beceriyi kazandırmak ve onların farkındalıklarını artırmaktır. Gereç ve Yöntemler: Araştırmanın birinci aşamasında, Trabzon ve Rize merkez ve ilçe hastanelerindeki pediatri servis hemşirelerine ön test soruları verildi. Testi cevaplayan hemşirelerle oluşturulan Whatsapp grubunda, tarafımca hazırlanan eğitim videosu paylaşıldı. İkinci aşamada; ön test sorularının aynısı, son test olarak tekrar uygulandı. İstatistiksel analiz için Jamovi (Sürüm 1.0.4) yazılımı kullanıldı. İstatistiksel anlamlılık için olasılık seviyesi p = 0,05 olarak belirlendi. Bulgular: Hem ön test hem de son testi cevaplayan 91 hemşirenin 83’ ü (91.2%) kadın, 8’i (8.8%) erkekti. Altı farklı bölümden oluşan test kategorisindeki tüm bölümlerde ( Diş Çürüğü, Diş Çürüklerinde Risk Faktörleri, Diş Çürüğünün Önlenmesi, Ağız ve Diş Yaralanmaları, Özel Bakım İhtiyacı Olan Çocuklar, Ne Yapmalı - Nasıl Yapılır?) eğitim sonrası yapılan son testteki başarı oranı anlamlı ölçüde artmıştı (p
{"title":"Increasing the Awareness of Pediatric Nurses about the Protection and Continuity of the Oral and Dental Health of Children","authors":"Ayça Kurt","doi":"10.7126/cumudj.1189055","DOIUrl":"https://doi.org/10.7126/cumudj.1189055","url":null,"abstract":"Objectives: To provide pediatric nurses with knowledge and skills on oral and dental health and to increase their awareness. \u0000Material and Methods: In the first phase of the study, pre-tests were given to pediatric nurses in Trabzon and Rize central and district hospitals. A Whatsapp group was created with the nurses who completed the tests, and the training video prepared by the researcher was shared. In the second phase of the study, the same questions were applied again as the post-test. Jamovi (Version 1.0.4) software was used for statistical analysis. P < 0.05 was accepted as statistically significant in all analyses. \u0000Results: Of the 91 nurses who completed both the pre-test and the post-test, 83 (91.2%) were female and 8 (8.8%) were male. In all sections in the test category consisting of six different sections (Tooth Decay, Risk Factors in Dental Caries, Prevention of Dental Caries, Oral and Dental Injuries, Children with Special Care Needs, What to Do - How to do?), the success rate was significantly higher in the post-test ( p < 0.001). \u0000Conclusion: Research emphasizes that neonatal nurses, pediatric nurses and health professionals working in community health centers should be activated and empowered in order to prevent oral and dental health problems of children, and awareness should be increased with scientifically valid educational guidelines. The results of the present study support these views and emphasize the importance of education by showing significant improvement with the training provided to nurses who had insufficient knowledge and awareness about the subject. \u0000 \u0000 \u0000 \u0000Amaç: Pediatri hemşirelerine ağız ve diş sağlığı konusundaki bilgi ve beceriyi kazandırmak ve onların farkındalıklarını artırmaktır. \u0000Gereç ve Yöntemler: Araştırmanın birinci aşamasında, Trabzon ve Rize merkez ve ilçe hastanelerindeki pediatri servis hemşirelerine ön test soruları verildi. Testi cevaplayan hemşirelerle oluşturulan Whatsapp grubunda, tarafımca hazırlanan eğitim videosu paylaşıldı. İkinci aşamada; ön test sorularının aynısı, son test olarak tekrar uygulandı. İstatistiksel analiz için Jamovi (Sürüm 1.0.4) yazılımı kullanıldı. İstatistiksel anlamlılık için olasılık seviyesi p = 0,05 olarak belirlendi. \u0000Bulgular: Hem ön test hem de son testi cevaplayan 91 hemşirenin 83’ ü (91.2%) kadın, 8’i (8.8%) erkekti. Altı farklı bölümden oluşan test kategorisindeki tüm bölümlerde ( Diş Çürüğü, Diş Çürüklerinde Risk Faktörleri, Diş Çürüğünün Önlenmesi, Ağız ve Diş Yaralanmaları, Özel Bakım İhtiyacı Olan Çocuklar, Ne Yapmalı - Nasıl Yapılır?) eğitim sonrası yapılan son testteki başarı oranı anlamlı ölçüde artmıştı (p","PeriodicalId":10781,"journal":{"name":"Cumhuriyet Dental Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42440549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amaç: Bu anket çalışmasının amacı; stajlarda çocuk hasta bakan diş hekimliği fakültesi öğrencilerinin, koruyucu diş hekimliği de içerisine alan çocuk diş hekimliğine yaklaşımını değerlendirmektir. Gereç ve Yöntemler: Amaca yönelik olarak 20 sorudan oluşan bir anket formu hazırlandı ve anket, öğrencilere sınav ortamından uzak stressiz bir ortamda online olarak uygulandı. Veriler bilgisayar ortamında kodlandı ve analiz edildi. Bulgular: Katılımcıların %55,9’u çocuk hasta bakmayı sevdiklerini belirtmişlerdir. %72,8’i çocuk hasta bakarken tedirgin olduğunu belirtirken, %16,9’u çocuk, %83,1’i yetişkin hastayı tedavi etmeyi tercih etmektedir. . Mezuniyet sonrasında meslek hayatlarında rutin olarak çocuk hasta tedavi etmeyi, %67,6’sı çok sık olmamakla birlikte düşünebilirim yanıtını verirken, %25’i evet, %7,4’ü ise mecbur kalmadıkça kesinlikle düşünmüyorum yanıtını vermiştir. Çocuk hasta bakarken kadınların daha tedirgin olmasına rağmen, çocuk hasta bakmayı erkelere göre daha çok tercih etmektedir (p0,05). Katılımcıların sınıflarına ve cinsiyete göre çocuk diş hekimliği hizmetinin en iyi verildiğini düşündükleri kurumlara ilişkin değerlendirmelerinde istatistiksel olarak anlamlı bir farklılık bulunmamaktadır (p>0,05). Her iki sınıf ve cinsiyet için en sık verilen yanıt diş hekimliği fakülteleri olmuştur. Sonuç: Ülkemizde çocuk ve genç nüfusunun fazla olmasına rağmen, geleceğin diş hekimi adayları, bu tedavilerde yeteri kadar istekli olmadıkları görülmüştür. Öğrenimleri süresince çocuk hastaları tedavi etmeye yönelik bilgi ve tecrübelerinin arttırılması, ileride daha çok sayıda çocuk hastayı tedavi edilebilmelerine yardımcı olacaktır.
Amaç:Bu anketçalışmasının amacı;在街上,儿童牙科科学评估儿童牙科科学的近似值,包括保护性牙科科学。要求和方法:Amaca编制了一份由20个问题组成的问卷,并在远程压力环境中在线应用于学生。数据在计算机环境中进行编码和分析。研究结果显示,55.9%的参与者喜欢看病人。当你观察72.8名儿童时,你更愿意用成年患者治疗16.9%的儿童。毕业后,我可以把孩子的常规治疗视为常规,67.6%的孩子没有太多反应,但25%的孩子有反应,7.4%的孩子不一定有反应。当孩子生病时,女性比男性更宽容(p0.05)。根据参与者的班级和性别,在评估他们认为儿童科学服务最好的机构方面没有统计学差异(p>0.05)。关于阶级和性,最常见的答案是牙科科学。Sonuç:Ülkemizdeçocuk ve gençnüfusunun fazla olmasına rağmen,geleceğin dişhekimi adayları,bu tedavilerde yeteri kadar istekli olmadıklarıgörülmüştür。在我的研究过程中,治疗儿童患者的信息和经验将有助于提高儿童患者的数量。
{"title":"Evaluating the Perspectives of the Faculty of Dentistry Students on Pediatric Dentistry: A Survey Study","authors":"S. Yi̇ldi̇z","doi":"10.7126/cumudj.1199372","DOIUrl":"https://doi.org/10.7126/cumudj.1199372","url":null,"abstract":"Amaç: Bu anket çalışmasının amacı; stajlarda çocuk hasta bakan diş hekimliği fakültesi öğrencilerinin, koruyucu diş hekimliği de içerisine alan çocuk diş hekimliğine yaklaşımını değerlendirmektir. \u0000Gereç ve Yöntemler: Amaca yönelik olarak 20 sorudan oluşan bir anket formu hazırlandı ve anket, öğrencilere sınav ortamından uzak stressiz bir ortamda online olarak uygulandı. Veriler bilgisayar ortamında kodlandı ve analiz edildi. \u0000Bulgular: Katılımcıların %55,9’u çocuk hasta bakmayı sevdiklerini belirtmişlerdir. %72,8’i çocuk hasta bakarken tedirgin olduğunu belirtirken, %16,9’u çocuk, %83,1’i yetişkin hastayı tedavi etmeyi tercih etmektedir. . Mezuniyet sonrasında meslek hayatlarında rutin olarak çocuk hasta tedavi etmeyi, %67,6’sı çok sık olmamakla birlikte düşünebilirim yanıtını verirken, %25’i evet, %7,4’ü ise mecbur kalmadıkça kesinlikle düşünmüyorum yanıtını vermiştir. Çocuk hasta bakarken kadınların daha tedirgin olmasına rağmen, çocuk hasta bakmayı erkelere göre daha çok tercih etmektedir (p0,05). Katılımcıların sınıflarına ve cinsiyete göre çocuk diş hekimliği hizmetinin en iyi verildiğini düşündükleri kurumlara ilişkin değerlendirmelerinde istatistiksel olarak anlamlı bir farklılık bulunmamaktadır (p>0,05). Her iki sınıf ve cinsiyet için en sık verilen yanıt diş hekimliği fakülteleri olmuştur. \u0000Sonuç: Ülkemizde çocuk ve genç nüfusunun fazla olmasına rağmen, geleceğin diş hekimi adayları, bu tedavilerde yeteri kadar istekli olmadıkları görülmüştür. Öğrenimleri süresince çocuk hastaları tedavi etmeye yönelik bilgi ve tecrübelerinin arttırılması, ileride daha çok sayıda çocuk hastayı tedavi edilebilmelerine yardımcı olacaktır.","PeriodicalId":10781,"journal":{"name":"Cumhuriyet Dental Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47268740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}