Jaroslav Zajíc, Aleš Mokráček, Ladislav Pešl, Jiří Haniš, Dita Schaffelhoferová
{"title":"(Extremely rare intrapericardial location of paraganglioma)","authors":"Jaroslav Zajíc, Aleš Mokráček, Ladislav Pešl, Jiří Haniš, Dita Schaffelhoferová","doi":"10.33678/cor.2023.002","DOIUrl":"https://doi.org/10.33678/cor.2023.002","url":null,"abstract":"","PeriodicalId":10787,"journal":{"name":"Cor et vasa","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135782545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Fadieienko, O. E. Gridnyev, O. Kurinna, N. Chereliuk
Background and the research aim: Nonalcoholic fatty liver disease (NAFLD) bears serious economic conse-quences for the health care system worldwide and Ukraine, in particular. Cardiovascular diseases (CVD) are the main cause of mortality in NAFLD patients. Changes in the gut microbiota composition can be regarded as a potential mechanism of CVD in NAFLD patients. The research aim was the investigation changes in major gut microbiota phylotypes, Bacteroidetes , Firmicutes , and Actinobacteria with quantifi cation of Firmi- cutes/Bacteroidetes in NAFLD patients with concomitant CVD. Materials and methods: There were 109 NAFLD subjects (25 with concomitant arterial hypertension [AH] and 24 with coronary artery disease [CAD]) enrolled. The gut microbiota composition was assessed by qPCR. Results and conclusions: There was a marked tendency towards an increase in the concentration of Bacteroidetes (by 37.11% and 21.30%, respectively) with a decrease in Firmicutes (by 7.38% and 7.77%, respectively) found in both groups with comorbid CAD and AH with the identifi ed changes not reaching a statistical signifi cance. A statistically signifi cant decrease in the concentration of Actinobacteria was revealed in patients with NAFLD with concomitant CAD at 41.37% ( p <0.05) as compared with those with an isolated NAFLD. In patients with concomitant AH, the content of Actinobacteria dropped by 12.35%, which was statistically insignifi cant. There were changes found in the intestinal microbiota composition, namely decrease in Actinobacteria in patients with CAD, which requires further research.
{"title":"Gut microbiota changes in nonalcoholic fatty liver disease and concomitant coronary artery disease","authors":"G. Fadieienko, O. E. Gridnyev, O. Kurinna, N. Chereliuk","doi":"10.33678/cor.2022.126","DOIUrl":"https://doi.org/10.33678/cor.2022.126","url":null,"abstract":"Background and the research aim: Nonalcoholic fatty liver disease (NAFLD) bears serious economic conse-quences for the health care system worldwide and Ukraine, in particular. Cardiovascular diseases (CVD) are the main cause of mortality in NAFLD patients. Changes in the gut microbiota composition can be regarded as a potential mechanism of CVD in NAFLD patients. The research aim was the investigation changes in major gut microbiota phylotypes, Bacteroidetes , Firmicutes , and Actinobacteria with quantifi cation of Firmi- cutes/Bacteroidetes in NAFLD patients with concomitant CVD. Materials and methods: There were 109 NAFLD subjects (25 with concomitant arterial hypertension [AH] and 24 with coronary artery disease [CAD]) enrolled. The gut microbiota composition was assessed by qPCR. Results and conclusions: There was a marked tendency towards an increase in the concentration of Bacteroidetes (by 37.11% and 21.30%, respectively) with a decrease in Firmicutes (by 7.38% and 7.77%, respectively) found in both groups with comorbid CAD and AH with the identifi ed changes not reaching a statistical signifi cance. A statistically signifi cant decrease in the concentration of Actinobacteria was revealed in patients with NAFLD with concomitant CAD at 41.37% ( p <0.05) as compared with those with an isolated NAFLD. In patients with concomitant AH, the content of Actinobacteria dropped by 12.35%, which was statistically insignifi cant. There were changes found in the intestinal microbiota composition, namely decrease in Actinobacteria in patients with CAD, which requires further research.","PeriodicalId":10787,"journal":{"name":"Cor et vasa","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48524228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mert Sarilar, V. Oktay, Gursu Demirci, D. Oksen, V. Sansoy
Background: Periprocedural myocardial injury and its clinical signifi cance in stable patients are still under discussion. This subject has been assessed in many studies with different defi nitions, thresholds, and biomarkers for years. This study aimed to determine the clinical outcomes of periprocedural myocardial injury based on latest 4th UDMI guideline defi nitions. Methods: 238 patients who underwent elective percutaneous coronary intervention at single center were retrospectively enrolled. Patients who developed periprocedural myocardial injury were compared with patients with normal troponin values after the procedure for clinical outcomes. Primary clinical endpoints were death, MI, stroke, refractory angina, target vessel revascularization and hospitalization due to acute coronary syndrome at one year. Results: Periprocedural myocardial injury was observed in 67.2% (n = 160) of patients. Number of lesions and stents, total stent length, total stent diameter, post-dilatation, overlapping stents, bifurcation stenting and SYNTAX score were signifi cantly higher in myocardial injury group. Clinical outcomes occurred in 16 patients, 11 of 16 had myocardial injury group, 5 of 16 had control group. No mortality was seen during the follow-up. Postprocedural troponin elevation was not associated with clinical outcomes (11 vs. 5, p = 0,56). Kaplan–Meier curve of clinical end points did not show any separation between the curves (Log rank test, 95% CI, p = 0,71). Conclusion: Stent size and length, post-dilatation, overlapping stents and stenting of bifurcation lesions lead to increase in myocardial injury. Periprocedural myocardial injury in stable angina does not predict clinical outcomes at one year.
背景:稳定患者术中心肌损伤及其临床意义仍在讨论中。多年来，这一主题在许多具有不同定义、阈值和生物标志物的研究中得到了评估。本研究旨在根据最新的第4版UDMI指南定义确定围手术期心肌损伤的临床结果。方法:238例在单中心行择期经皮冠状动脉介入治疗的患者进行回顾性分析。术后发生围手术期心肌损伤的患者与肌钙蛋白值正常的患者进行临床结果比较。主要临床终点为一年内死亡、心肌梗死、卒中、难治性心绞痛、靶血管重建术和因急性冠状动脉综合征住院。结果:术中心肌损伤发生率为67.2%(160例)。心肌损伤组病变及支架数量、支架总长度、支架总直径、扩张后、支架重叠、支架术分岔及SYNTAX评分均显著高于心肌损伤组。16例患者发生临床结局，16例中心肌损伤组11例，对照组5例。随访期间未见死亡。术后肌钙蛋白升高与临床结果无关(11比5,p = 0,56)。Kaplan-Meier曲线的临床终点之间没有任何分离(Log rank检验，95% CI, p = 0,71)。结论:支架的大小和长度、扩张后支架、重叠支架和分叉病变支架置入导致心肌损伤增加。稳定性心绞痛围手术期心肌损伤不能预测一年后的临床结果。
{"title":"Periprocedural myocardial injury after elective percutaneous coronary intervention in stable angina pectoris: a tertiary center experience","authors":"Mert Sarilar, V. Oktay, Gursu Demirci, D. Oksen, V. Sansoy","doi":"10.33678/cor.2022.111","DOIUrl":"https://doi.org/10.33678/cor.2022.111","url":null,"abstract":"Background: Periprocedural myocardial injury and its clinical signifi cance in stable patients are still under discussion. This subject has been assessed in many studies with different defi nitions, thresholds, and biomarkers for years. This study aimed to determine the clinical outcomes of periprocedural myocardial injury based on latest 4th UDMI guideline defi nitions. Methods: 238 patients who underwent elective percutaneous coronary intervention at single center were retrospectively enrolled. Patients who developed periprocedural myocardial injury were compared with patients with normal troponin values after the procedure for clinical outcomes. Primary clinical endpoints were death, MI, stroke, refractory angina, target vessel revascularization and hospitalization due to acute coronary syndrome at one year. Results: Periprocedural myocardial injury was observed in 67.2% (n = 160) of patients. Number of lesions and stents, total stent length, total stent diameter, post-dilatation, overlapping stents, bifurcation stenting and SYNTAX score were signifi cantly higher in myocardial injury group. Clinical outcomes occurred in 16 patients, 11 of 16 had myocardial injury group, 5 of 16 had control group. No mortality was seen during the follow-up. Postprocedural troponin elevation was not associated with clinical outcomes (11 vs. 5, p = 0,56). Kaplan–Meier curve of clinical end points did not show any separation between the curves (Log rank test, 95% CI, p = 0,71). Conclusion: Stent size and length, post-dilatation, overlapping stents and stenting of bifurcation lesions lead to increase in myocardial injury. Periprocedural myocardial injury in stable angina does not predict clinical outcomes at one year.","PeriodicalId":10787,"journal":{"name":"Cor et vasa","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41851547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Dogan, D. Mansuroğlu, Oğuz Konukoğlu, Emrah Ozdemir, Mert Sarilar, Ayda Guler, N. Kurtoglu
Background : Hemodynamic parameters have recently emerged as tools for risk stratifi cation of heart failure patients. Cardiac power output (CPO) is an indicator of cardiac performance. Cardiac power index (CPI) is calculated by indexing CPO to body surface area. The study aimed to demonstrate the prognostic role of resting CPI in advanced chronic heart failure patients. Methods : The study included patients with advanced chronic heart failure, ejection fraction below 30%, and classes III and IV functional capacity who had had right and left heart catheterization. A total of 99 patients were enrolled, with those having left ventricular assist device (LVAD) implantation or heart transplantation (HTx) excluded to determine LVAD- and HTx-free survival. Results : Of the 99 patients, 43 patients underwent LVAD and HTx surgery. Of the remaining 56 patients, 19 died (33.9%) over a period of 16 months (median). The value of CPI was associated with cardiac mortality (0.32 vs 0.42, p = 0.003). The cut-off level of CPI for mortality was 0.41 (89.5% sensitivity and 56.8% specifi city). A diminished CPI (<0.41 W/m 2 ) was also associated with high right atrial pressure ( p = 0.016) and pulmonary vascular resistance ( p = 0.012). A Kaplan–Meier survival analysis indicated that long-term survival was signifi cantly reduced in patients with CPI <0.41. Conclusion : Cardiac power index at rest is associated with cardiac mortality in patients with advanced chronic heart failure.
背景:血液动力学参数最近成为心衰患者风险分层的工具。心功率输出(CPO)是心脏功能的一个指标。心力指数(CPI)是通过将CPO与体表面积挂钩来计算的。本研究旨在证明静息CPI在晚期慢性心力衰竭患者的预后作用。方法:研究对象为晚期慢性心力衰竭、射血分数低于30%、III级和IV级功能容量且行左、右心导管术的患者。共纳入99例患者，排除植入左心室辅助装置(LVAD)或心脏移植(HTx)的患者，以确定无LVAD和无HTx的生存期。结果:99例患者中43例行LVAD + HTx手术。在其余56例患者中，19例(33.9%)在16个月(中位)期间死亡。CPI值与心脏死亡率相关(0.32 vs 0.42, p = 0.003)。死亡率CPI的临界值为0.41(敏感性为89.5%，特异性为56.8%)。CPI降低(<0.41 W/ m2)还与高右房压(p = 0.016)和肺血管阻力(p = 0.012)相关。Kaplan-Meier生存分析显示，CPI <0.41的患者的长期生存显著降低。结论:静息时心功率指数与晚期慢性心力衰竭患者心脏死亡率相关。
{"title":"Impact of invasively determined cardiac power index on survival in patients with advanced chronic heart failure","authors":"Ali Dogan, D. Mansuroğlu, Oğuz Konukoğlu, Emrah Ozdemir, Mert Sarilar, Ayda Guler, N. Kurtoglu","doi":"10.33678/cor.2022.100","DOIUrl":"https://doi.org/10.33678/cor.2022.100","url":null,"abstract":"Background : Hemodynamic parameters have recently emerged as tools for risk stratifi cation of heart failure patients. Cardiac power output (CPO) is an indicator of cardiac performance. Cardiac power index (CPI) is calculated by indexing CPO to body surface area. The study aimed to demonstrate the prognostic role of resting CPI in advanced chronic heart failure patients. Methods : The study included patients with advanced chronic heart failure, ejection fraction below 30%, and classes III and IV functional capacity who had had right and left heart catheterization. A total of 99 patients were enrolled, with those having left ventricular assist device (LVAD) implantation or heart transplantation (HTx) excluded to determine LVAD- and HTx-free survival. Results : Of the 99 patients, 43 patients underwent LVAD and HTx surgery. Of the remaining 56 patients, 19 died (33.9%) over a period of 16 months (median). The value of CPI was associated with cardiac mortality (0.32 vs 0.42, p = 0.003). The cut-off level of CPI for mortality was 0.41 (89.5% sensitivity and 56.8% specifi city). A diminished CPI (<0.41 W/m 2 ) was also associated with high right atrial pressure ( p = 0.016) and pulmonary vascular resistance ( p = 0.012). A Kaplan–Meier survival analysis indicated that long-term survival was signifi cantly reduced in patients with CPI <0.41. Conclusion : Cardiac power index at rest is associated with cardiac mortality in patients with advanced chronic heart failure.","PeriodicalId":10787,"journal":{"name":"Cor et vasa","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45096341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zuzana Komorová, M. Novák, J. Seménka, V. Feitová, P. Nemec, L. Špinarová
{"title":"(Left-right short circuit in an adult woman between the left coronary artery and the sinus coronarius caused by a giant fistula)","authors":"Zuzana Komorová, M. Novák, J. Seménka, V. Feitová, P. Nemec, L. Špinarová","doi":"10.33678/cor.2022.078","DOIUrl":"https://doi.org/10.33678/cor.2022.078","url":null,"abstract":"","PeriodicalId":10787,"journal":{"name":"Cor et vasa","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42108055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Hodboďová, A. Krebsová, P. Peldová, R. Polášek, T. Roubíček
Hypertrophic cardiomyopathy (HCM) affects 0.2% of the population and is the most common form of here- ditary heart muscle disease in adults. The most frequent cause of HCM are changes in the genes encoding sarcomere proteins. However, up to 10% of patients are affected by another type of systemic genetic dis- ease that has myocardial hypertrophy as only one of its multi-organ manifestations. Among these diseases is PRKAG2 glycogenosis, a rare metabolic storage disorder caused by an inherited defect in the 2 regula-tory subunit of adenosine monophosphate-activated protein kinase (AMPK). In addition to skeletal muscle myopathy, it causes HCMP with a high risk of malignant ventricular and supraventricular arrhythmias and several conduction disorders. Thanks to close collaboration of several departments, we diagnosed two families with a causative DNA variant in the PRKAG2 gene. On the basis of the presented case studies, we document highly variable manifestations of PRKAG2 syndrome and thus highlight the pitfalls in its clinical diagnosis and therapy
{"title":"(PRKAG2 syndrome as a highly arrhythmogenic eventuality in the differential diagnosis of hypertrophic cardiomyopathy - an example of two families with a confirmed causative DNA variant)","authors":"M. Hodboďová, A. Krebsová, P. Peldová, R. Polášek, T. Roubíček","doi":"10.33678/cor.2022.116","DOIUrl":"https://doi.org/10.33678/cor.2022.116","url":null,"abstract":"Hypertrophic cardiomyopathy (HCM) affects 0.2% of the population and is the most common form of here- ditary heart muscle disease in adults. The most frequent cause of HCM are changes in the genes encoding sarcomere proteins. However, up to 10% of patients are affected by another type of systemic genetic dis- ease that has myocardial hypertrophy as only one of its multi-organ manifestations. Among these diseases is PRKAG2 glycogenosis, a rare metabolic storage disorder caused by an inherited defect in the 2 regula-tory subunit of adenosine monophosphate-activated protein kinase (AMPK). In addition to skeletal muscle myopathy, it causes HCMP with a high risk of malignant ventricular and supraventricular arrhythmias and several conduction disorders. Thanks to close collaboration of several departments, we diagnosed two families with a causative DNA variant in the PRKAG2 gene. On the basis of the presented case studies, we document highly variable manifestations of PRKAG2 syndrome and thus highlight the pitfalls in its clinical diagnosis and therapy","PeriodicalId":10787,"journal":{"name":"Cor et vasa","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47203870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Asma Amrani-Midoun, N. Laredj, Taki Djebaili, Abdelkader Djelloul, L. Zouli, H. Aoumeur, F. Boukerche, M. Nachi
Background and aims: The aim of this study is to determine the role of clinical, lifestyle, and behavioral characteristics on the severity of the disease according to the gender. Methods: We conducted a cross-sectional descriptive study. Results: An initial sample of 1219 patients was admitted for ACS in the cardiology service of Oran-Univer-sity-Hospital-Center. The electrocardiographic results revealed that 34% of the patients had ST-segment elevation myocardial infarction (STEMI) while 66% had non-ST-segment elevation myocardial infarction (NSTEMI). In STEMI patients, the mean age was 60.87±12.20 years. STEMI patients sample included 413 pa- tients with 324 men with a mean age of 59.92±11.78 years and 89 women with a mean age of 64.36±13.13 years. A male predominance observed with a sex-ratio of 3.6. Among STEMI patients, 34.8% of patients had hypertension where it was signifi cantly higher in women than in men (65.6% vs 26.5% respectively, p < 0.05). Diabetes was observed in 31.7% of the whole sample where it was also more common in women compared to men (50.6% vs 26.5%, respectively, p <0.05). Out of the 413 STEMI patients 63.9% had dyslipidemia which was signifi cantly higher in men compared to women (76.5% vs 13.5% respectively, p <0.05), 64.5% of men were current smokers. Out of the 324 STEMI men patients, 46.5% had three risk factors while in the 89 STEMI women patients, 34.8% had four risk factors. Conclusion: Our results demonstrated a higher prevalence of ACS among the studied sample. STEMI patients presented with several cardiovascular risk factors. Sex differences in the ACS presentation and risk factors was also noticed.
背景和目的:本研究的目的是根据性别确定临床、生活方式和行为特征对疾病严重程度的作用。方法:我们进行了横断面描述性研究。结果:奥兰-大学-医院中心心脏病科收治了1219例ACS患者。心电图结果显示，34%的患者为st段抬高型心肌梗死(STEMI)， 66%的患者为非st段抬高型心肌梗死(NSTEMI)。STEMI患者的平均年龄为60.87±12.20岁。STEMI患者共413例，其中男性324例，平均年龄59.92±11.78岁，女性89例，平均年龄64.36±13.13岁。雄性优势，性别比为3.6。在STEMI患者中，34.8%的患者有高血压，其中女性明显高于男性(65.6% vs 26.5%， p < 0.05)。31.7%的人患有糖尿病，其中女性比男性更常见(50.6%比26.5%，p <0.05)。在413例STEMI患者中，63.9%患有血脂异常，男性明显高于女性(分别为76.5%对13.5%，p <0.05)， 64.5%的男性目前是吸烟者。在324例STEMI男性患者中，46.5%有3种危险因素，而在89例STEMI女性患者中，34.8%有4种危险因素。结论:我们的研究结果表明，在研究样本中ACS的患病率较高。STEMI患者存在多种心血管危险因素。ACS的表现和危险因素的性别差异也被注意到了。
{"title":"Gender differences in epidemiology and risk factors of acute coronary syndrome in Algerian patients of the Oran city: descriptive cross-sectional study","authors":"Asma Amrani-Midoun, N. Laredj, Taki Djebaili, Abdelkader Djelloul, L. Zouli, H. Aoumeur, F. Boukerche, M. Nachi","doi":"10.33678/cor.2022.114","DOIUrl":"https://doi.org/10.33678/cor.2022.114","url":null,"abstract":"Background and aims: The aim of this study is to determine the role of clinical, lifestyle, and behavioral characteristics on the severity of the disease according to the gender. Methods: We conducted a cross-sectional descriptive study. Results: An initial sample of 1219 patients was admitted for ACS in the cardiology service of Oran-Univer-sity-Hospital-Center. The electrocardiographic results revealed that 34% of the patients had ST-segment elevation myocardial infarction (STEMI) while 66% had non-ST-segment elevation myocardial infarction (NSTEMI). In STEMI patients, the mean age was 60.87±12.20 years. STEMI patients sample included 413 pa- tients with 324 men with a mean age of 59.92±11.78 years and 89 women with a mean age of 64.36±13.13 years. A male predominance observed with a sex-ratio of 3.6. Among STEMI patients, 34.8% of patients had hypertension where it was signifi cantly higher in women than in men (65.6% vs 26.5% respectively, p < 0.05). Diabetes was observed in 31.7% of the whole sample where it was also more common in women compared to men (50.6% vs 26.5%, respectively, p <0.05). Out of the 413 STEMI patients 63.9% had dyslipidemia which was signifi cantly higher in men compared to women (76.5% vs 13.5% respectively, p <0.05), 64.5% of men were current smokers. Out of the 324 STEMI men patients, 46.5% had three risk factors while in the 89 STEMI women patients, 34.8% had four risk factors. Conclusion: Our results demonstrated a higher prevalence of ACS among the studied sample. STEMI patients presented with several cardiovascular risk factors. Sex differences in the ACS presentation and risk factors was also noticed.","PeriodicalId":10787,"journal":{"name":"Cor et vasa","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47878978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Snopek, J. Hasilla, L. Pátrovič, D. Juskanič, J. Benko, M. Samoš
Symptomatic neurological complications occur in 15–30% of patients with infective endocarditis. At the same time, other clinically silent cerebral embolisms occur in 35–60% of patients. Staphylococcus aureus is the pathogen that causes nervous system involvement most frequently. We report a case of a 67-year- -old man with infective endocarditis following a dental procedure that manifested as spondylodiscitis and multiple brain embolization, including a brain abscess that required drainage. After six weeks of treatment with broad-spectrum antibiotics and complex supportive therapy, we discharged the patient in a satisfactory mental and somatic condition. The preparation of the patient for cardiac surgery is ongoing.
{"title":"Infective endocarditis complicated by brain embolism: a case report","authors":"P. Snopek, J. Hasilla, L. Pátrovič, D. Juskanič, J. Benko, M. Samoš","doi":"10.33678/cor.2022.129","DOIUrl":"https://doi.org/10.33678/cor.2022.129","url":null,"abstract":"Symptomatic neurological complications occur in 15–30% of patients with infective endocarditis. At the same time, other clinically silent cerebral embolisms occur in 35–60% of patients. Staphylococcus aureus is the pathogen that causes nervous system involvement most frequently. We report a case of a 67-year- -old man with infective endocarditis following a dental procedure that manifested as spondylodiscitis and multiple brain embolization, including a brain abscess that required drainage. After six weeks of treatment with broad-spectrum antibiotics and complex supportive therapy, we discharged the patient in a satisfactory mental and somatic condition. The preparation of the patient for cardiac surgery is ongoing.","PeriodicalId":10787,"journal":{"name":"Cor et vasa","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48976359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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