Pub Date : 2023-12-20DOI: 10.2174/0122133461270888231128050236
Ayan Bandyopadhyay, Rajib Sarkar
Electro-organic synthesis, an atom-efficient, sustainable, mild process, permits an ecofriendly and elegant green path to synthesize structurally complex, still valuable molecules, avoiding the use of conventional harsh oxidizing and reducing agents and long-route reaction protocols. Being one of the oldest forms of reaction setups in a laboratory, it deals with fundamental redox chemistry through the direct application of electrical potential. Here flow of electrons acts as an oxidizing agent at the anode at the same time reducing agent at the cathode, depending upon the requirement of the reaction. Simultaneously, it minimizes the generation of reagent waste during the reaction. However, electrifying organic synthesis plays more than preventing the waste footprint. This technology provides an alternative roadmap through nonclassical bond disconnections to access desired target molecules by cutting down a number of steps with the formation of apparently looking difficult bonds with excellent regio-, chemo-and stereoselectivity. Hence, it emerges as an alternative and attractive technique for the contemporary synthetic communities. Consequently, in recent years, multiple milestones have been achieved in the electro-organic synthesis of fascinating natural products through oxidative C-C bond formation, C-H/N-H functionalization, very rare oxidative N-N dimerization, RCDA dimerization, etc. Thus, synthesis of extremely complex natural products through finding new electro-synthetic route as a key methodology have become one of the alluring synthetic targets to synthetic chemists because of their versatile utilities in medicine, agriculture, food, and cosmetic industry. This review presents advances in electrochemistry in the total synthesis of 20 complex natural products reported since 2013. Enabling synthetic steps are analyzed alongside innate advantages as well as future prospects are speculated.
{"title":"Organic Electrosynthesis: A Promising Green Tool in Solving Key Steps for the Total Synthesis of Complex Natural Products","authors":"Ayan Bandyopadhyay, Rajib Sarkar","doi":"10.2174/0122133461270888231128050236","DOIUrl":"https://doi.org/10.2174/0122133461270888231128050236","url":null,"abstract":"Electro-organic synthesis, an atom-efficient, sustainable, mild process, permits an ecofriendly and elegant green path to synthesize structurally complex, still valuable molecules, avoiding the use of conventional harsh oxidizing and reducing agents and long-route reaction protocols. Being one of the oldest forms of reaction setups in a laboratory, it deals with fundamental redox chemistry through the direct application of electrical potential. Here flow of electrons acts as an oxidizing agent at the anode at the same time reducing agent at the cathode, depending upon the requirement of the reaction. Simultaneously, it minimizes the generation of reagent waste during the reaction. However, electrifying organic synthesis plays more than preventing the waste footprint. This technology provides an alternative roadmap through nonclassical bond disconnections to access desired target molecules by cutting down a number of steps with the formation of apparently looking difficult bonds with excellent regio-, chemo-and stereoselectivity. Hence, it emerges as an alternative and attractive technique for the contemporary synthetic communities. Consequently, in recent years, multiple milestones have been achieved in the electro-organic synthesis of fascinating natural products through oxidative C-C bond formation, C-H/N-H functionalization, very rare oxidative N-N dimerization, RCDA dimerization, etc. Thus, synthesis of extremely complex natural products through finding new electro-synthetic route as a key methodology have become one of the alluring synthetic targets to synthetic chemists because of their versatile utilities in medicine, agriculture, food, and cosmetic industry. This review presents advances in electrochemistry in the total synthesis of 20 complex natural products reported since 2013. Enabling synthetic steps are analyzed alongside innate advantages as well as future prospects are speculated.","PeriodicalId":10856,"journal":{"name":"Current Green Chemistry","volume":"34 S1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139168409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-10DOI: 10.2174/0122133461279579231103055412
Sameea Ahmed Khan, Rajesh Sharma
Abstract: Green synthesized metal nanoparticles offer a broad spectrum of applications. They also offer unmatched significance because they are eco-friendly, cost-effective, and less toxic to human beings. Copper nanoparticles, when synthesized using green protocols, exhibit enriched properties and are substantially used in the preparation of nanofluids, medicine, conductive agents, etc. In this review, we have highlighted how the side effects of synthetic compounds have paved the way to look for greener alternatives in the field of nanomedicine. Green fabrication, characterization, and activities of copper nanoparticles using different biological sources have been extensively studied and reported. The biological sources have been broadly classified into two categories, plant-based and microbial-based. Natural resources are a reservoir of flavonoids, polyphenols, saponins, etc. They act as reducing and stabilizing agents for nanoparticles. Bio-synthesized metal nanoparticles have presented themselves as anti-microbial agents, bioreductors, cytotoxic agents, bioremediators, etc. This review has described the effective utilization of natural resources for synthesizing copper nanoparticles. It also emphasizes the recent developments in this field covering the diverse applications of the same.
{"title":"Eco-friendly Synthesis of Copper Nanoparticles: An Overview of the Epoch-making Role of Natural Resources, Applications, and Recent Developments","authors":"Sameea Ahmed Khan, Rajesh Sharma","doi":"10.2174/0122133461279579231103055412","DOIUrl":"https://doi.org/10.2174/0122133461279579231103055412","url":null,"abstract":"Abstract: Green synthesized metal nanoparticles offer a broad spectrum of applications. They also offer unmatched significance because they are eco-friendly, cost-effective, and less toxic to human beings. Copper nanoparticles, when synthesized using green protocols, exhibit enriched properties and are substantially used in the preparation of nanofluids, medicine, conductive agents, etc. In this review, we have highlighted how the side effects of synthetic compounds have paved the way to look for greener alternatives in the field of nanomedicine. Green fabrication, characterization, and activities of copper nanoparticles using different biological sources have been extensively studied and reported. The biological sources have been broadly classified into two categories, plant-based and microbial-based. Natural resources are a reservoir of flavonoids, polyphenols, saponins, etc. They act as reducing and stabilizing agents for nanoparticles. Bio-synthesized metal nanoparticles have presented themselves as anti-microbial agents, bioreductors, cytotoxic agents, bioremediators, etc. This review has described the effective utilization of natural resources for synthesizing copper nanoparticles. It also emphasizes the recent developments in this field covering the diverse applications of the same.","PeriodicalId":10856,"journal":{"name":"Current Green Chemistry","volume":"102 42","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135136670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract: Pharmaceutical contamination, resulting from the discharge of active pharmaceutical ingredients (APIs) and other related compounds into the water, has become a growing concern due to its potential adverse effects on ecosystems and human health. This review article aims to examine the many facets of pharmaceutical contamination and highlight the most recent developments in its remediation. The effects of pharmaceuticals, sources, and pathways of pharmaceutical contamination, as well as the difficulties in detecting and evaluating its toxicities, have been included in the present manuscript. Nowadays various remediation strategies are employed to mitigate pharmaceutical contamination in water. Conventional wastewater treatment techniques, including activated sludge processes and membrane filtration, are effective in removing a portion of the pharmaceutical compounds. However, advanced oxidation processes such as ozonation and photocatalysis have shown promising results in enhancing the degradation of recalcitrant APIs. Nanotechnology-based approaches, such as the use of nanoparticles for adsorption and degradation, and bioremediation methods utilizing microbial degradation, enzymatic processes, and phytoremediation, offer potential future directions for efficient and sustainable remediation. This review describes the most recent developments, current status, and potential research directions with the future prospects of pharmaceutical pollutants.
{"title":"Pharmaceuticals in the Water: Emerging Concerns and Innovative Remediation Solutions","authors":"Smriti Ojha, Shivendra Mani Tripathi, Pratik Kumar Vishwakarma, Sudhanshu Mishra","doi":"10.2174/0122133461272526231012064151","DOIUrl":"https://doi.org/10.2174/0122133461272526231012064151","url":null,"abstract":"Abstract: Pharmaceutical contamination, resulting from the discharge of active pharmaceutical ingredients (APIs) and other related compounds into the water, has become a growing concern due to its potential adverse effects on ecosystems and human health. This review article aims to examine the many facets of pharmaceutical contamination and highlight the most recent developments in its remediation. The effects of pharmaceuticals, sources, and pathways of pharmaceutical contamination, as well as the difficulties in detecting and evaluating its toxicities, have been included in the present manuscript. Nowadays various remediation strategies are employed to mitigate pharmaceutical contamination in water. Conventional wastewater treatment techniques, including activated sludge processes and membrane filtration, are effective in removing a portion of the pharmaceutical compounds. However, advanced oxidation processes such as ozonation and photocatalysis have shown promising results in enhancing the degradation of recalcitrant APIs. Nanotechnology-based approaches, such as the use of nanoparticles for adsorption and degradation, and bioremediation methods utilizing microbial degradation, enzymatic processes, and phytoremediation, offer potential future directions for efficient and sustainable remediation. This review describes the most recent developments, current status, and potential research directions with the future prospects of pharmaceutical pollutants.","PeriodicalId":10856,"journal":{"name":"Current Green Chemistry","volume":"51 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135414682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-20DOI: 10.2174/0122133461267868231018100148
Anjali Jha, V R Krishnam Raju
Abstract: Many medicinally active new chemical entities depend on indole-conjugated chromeno[ b]pyridine derivatives as a building block. The synthesis of 4-(1H-indol-3-yl)-3,4-dihydro-1Hchromeno[ 4,3-d]pyrimidine-2,5-dione 4 was developed in the current study by treating 4-hydroxy- 2H-chromen-2-one 1, indole aldehydes 2, and urea/thiourea 3 in the presence of L-proline as catalyst in ethanol as solvent for 2-3 hours at 70-75°C with yields of 80-85%, and their structures were characterized by various spectral techniques. The synthesized compounds were tested for their potential to inhibit cancer growth in HepG2 and MDA-MD-231 cells. Out of all the compounds, compound 4b displayed noteworthy cytotoxicity with IC50 values of 8.1 and 9.2 μM against HepG2 and MDAMD- 231, respectively. Additionally, insilico studies indicated that compound 4b had favorable binding energy (-7.8 kcal/mol) when compared to the co-crystal ligand (LS5) in inhibiting the human cyclin-dependent kinase 2 (CDK2) protein.
{"title":"Eco-friendly Synthesis of Indole Conjugated Chromeno[B]Pyridines as Anti-cancer agents and their Molecular Modelling Studies","authors":"Anjali Jha, V R Krishnam Raju","doi":"10.2174/0122133461267868231018100148","DOIUrl":"https://doi.org/10.2174/0122133461267868231018100148","url":null,"abstract":"Abstract: Many medicinally active new chemical entities depend on indole-conjugated chromeno[ b]pyridine derivatives as a building block. The synthesis of 4-(1H-indol-3-yl)-3,4-dihydro-1Hchromeno[ 4,3-d]pyrimidine-2,5-dione 4 was developed in the current study by treating 4-hydroxy- 2H-chromen-2-one 1, indole aldehydes 2, and urea/thiourea 3 in the presence of L-proline as catalyst in ethanol as solvent for 2-3 hours at 70-75°C with yields of 80-85%, and their structures were characterized by various spectral techniques. The synthesized compounds were tested for their potential to inhibit cancer growth in HepG2 and MDA-MD-231 cells. Out of all the compounds, compound 4b displayed noteworthy cytotoxicity with IC50 values of 8.1 and 9.2 μM against HepG2 and MDAMD- 231, respectively. Additionally, insilico studies indicated that compound 4b had favorable binding energy (-7.8 kcal/mol) when compared to the co-crystal ligand (LS5) in inhibiting the human cyclin-dependent kinase 2 (CDK2) protein.","PeriodicalId":10856,"journal":{"name":"Current Green Chemistry","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135666268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract: An ultrasound-assisted catalyst-free green protocol has been developed for the synthesis of a series of diversely substituted Knoevenagel condensation products from the reaction between functionalized aromatic aldehydes/isatin derivatives and substituted malononitriles as the C-H acids in water at ambient conditions. The method is simple, straightforward, and highly efficient. The major advantages of this newly developed protocol are expedient catalyst-free synthesis, good to excellent yields, energy efficiency, use of water as reaction medium, easy isolation of products, no need for column chromatographic purification, eco-friendliness, and operational simplicity.
{"title":"Ultrasound-Assisted Catalyst-Free Knoevenagel Condensation of Carbonyl Compounds with C – H Acids in Water","authors":"Goutam Brahmachari, Indrajit Karmakar, Mullicka Mandal, Bhagirath Mandal","doi":"10.2174/0122133461268098231004072803","DOIUrl":"https://doi.org/10.2174/0122133461268098231004072803","url":null,"abstract":"Abstract: An ultrasound-assisted catalyst-free green protocol has been developed for the synthesis of a series of diversely substituted Knoevenagel condensation products from the reaction between functionalized aromatic aldehydes/isatin derivatives and substituted malononitriles as the C-H acids in water at ambient conditions. The method is simple, straightforward, and highly efficient. The major advantages of this newly developed protocol are expedient catalyst-free synthesis, good to excellent yields, energy efficiency, use of water as reaction medium, easy isolation of products, no need for column chromatographic purification, eco-friendliness, and operational simplicity.","PeriodicalId":10856,"journal":{"name":"Current Green Chemistry","volume":"204 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136253937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-04DOI: 10.2174/0122133461255437230930182648
Henrique Esteves, Nathália Evelyn Morais Costa, Vinicius Kalil Tomazett, Jorge Luiz Sônego Milani, Rafael Pavão das Chagas, Ângelo de Fátima
Abstract: Organocatalysed reactions are becoming powerful tools in the construction of complex molecular skeletons. It gains extra importance when used as a chemical approach to the chemical fixation of carbon dioxide (CO2). Carbon dioxide is an increasingly dangerous environmental hazard as the global climate temperature rises through the greenhouse effect. Meanwhile, in the past decades, significant advances can be noted in the use of organocatalysis for CO2 capture and its conversion into valuable chemicals. Therefore, herein we review a full set of organocatalysts used in CO2 fixation for the synthesis of N-heterocycles since they are present in several chemical structures with biological relevance.
{"title":"Organocatalysis for the Chemical Fixation of Carbon Dioxide to Synthesise N-Heterocycles","authors":"Henrique Esteves, Nathália Evelyn Morais Costa, Vinicius Kalil Tomazett, Jorge Luiz Sônego Milani, Rafael Pavão das Chagas, Ângelo de Fátima","doi":"10.2174/0122133461255437230930182648","DOIUrl":"https://doi.org/10.2174/0122133461255437230930182648","url":null,"abstract":"Abstract: Organocatalysed reactions are becoming powerful tools in the construction of complex molecular skeletons. It gains extra importance when used as a chemical approach to the chemical fixation of carbon dioxide (CO2). Carbon dioxide is an increasingly dangerous environmental hazard as the global climate temperature rises through the greenhouse effect. Meanwhile, in the past decades, significant advances can be noted in the use of organocatalysis for CO2 capture and its conversion into valuable chemicals. Therefore, herein we review a full set of organocatalysts used in CO2 fixation for the synthesis of N-heterocycles since they are present in several chemical structures with biological relevance.","PeriodicalId":10856,"journal":{"name":"Current Green Chemistry","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135647379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract: The modern world of chemistry needs to find a sustainable solution for the remediation of heavy metals. The method of solving heavy metal problems using abundant and easily available ways is an integral part of green chemistry. This approach stimulates innovation among scientists. These procedures increase performance and decrease the consumption of non-renewable resources, minimizing negative impacts on the environment and less use of harmful chemicals. In this review, we have included some natural ways for the remediation of heavy metals such as Biochar, Clay, Zeolites, and Microorganism-based methods. We have also incorporated the mechanism of action of each of these procedures for the betterment of the reader.
{"title":"Biochar, Clay, Zeolites, and Microorganism-Based Methods for Remediation of Heavy Metals","authors":"Yukti Monga, Shivangi Sharma, Shivendra Singh, Ashu Gupta","doi":"10.2174/2213346110666230915140448","DOIUrl":"https://doi.org/10.2174/2213346110666230915140448","url":null,"abstract":"Abstract: The modern world of chemistry needs to find a sustainable solution for the remediation of heavy metals. The method of solving heavy metal problems using abundant and easily available ways is an integral part of green chemistry. This approach stimulates innovation among scientists. These procedures increase performance and decrease the consumption of non-renewable resources, minimizing negative impacts on the environment and less use of harmful chemicals. In this review, we have included some natural ways for the remediation of heavy metals such as Biochar, Clay, Zeolites, and Microorganism-based methods. We have also incorporated the mechanism of action of each of these procedures for the betterment of the reader.","PeriodicalId":10856,"journal":{"name":"Current Green Chemistry","volume":"356 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135438624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The development of synthetic methodologies to obtain a diverse range of heterocyclic scaffolds has been a very attractive area of research due to their vast therapeutic importance. Conventional approaches that require the use of organic solvents, which are generally flammable, toxic, and not eco-friendly, are replaced either with greener alternatives or by completely avoiding their use. In literature, several solvent-free methods are being developed to achieve the synthesis of vast varieties of organic compounds. This review focuses on the solvent-free methods developed for the synthesis of different types of nitrogen and oxygen heterocycles which have exhibited diverse therapeutic applications.
{"title":"Solvent-Free Approaches towards the Synthesis of Therapeutically Important Heterocycles","authors":"Ambarish Priyadarshan, Garima Tripathi, Anil Kumar Singh, Sanchiyata Rajkhowa, Abhijeet Kumar, Vinod K. Tiwari","doi":"10.2174/2213346110666230915163034","DOIUrl":"https://doi.org/10.2174/2213346110666230915163034","url":null,"abstract":"The development of synthetic methodologies to obtain a diverse range of heterocyclic scaffolds has been a very attractive area of research due to their vast therapeutic importance. Conventional approaches that require the use of organic solvents, which are generally flammable, toxic, and not eco-friendly, are replaced either with greener alternatives or by completely avoiding their use. In literature, several solvent-free methods are being developed to achieve the synthesis of vast varieties of organic compounds. This review focuses on the solvent-free methods developed for the synthesis of different types of nitrogen and oxygen heterocycles which have exhibited diverse therapeutic applications.","PeriodicalId":10856,"journal":{"name":"Current Green Chemistry","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135438626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.2174/2213346110666230607150014
Latifa Khattabi, Moussa Mokhtari, M. Bouhenna, Ahmed Fellak, Mohamed Abu-Mustapha, Saleh Akkal, Feriel Sellam
Expanding utilization of pesticides can provoke serious issues due to their biomagnification and persistent nature. Eventual contamination of fresh daily-consumed food by pesticide constitutes a human food security problem. The present investigation planned to check out whether the most hazardous pesticides could be found in a varied collection of wheat, vegetables and fruit, on the other hand, we attempted to know if some banned and no more commercialized pesticides could be even detected. Effectively, we have chosen to analyze wheat, potato, tomato, apple, peach and grape, so, after the extraction procedure of pesticides, we used gas chromatography-mass spectrometry (GC-MS) to identify some hazardous compounds (organochlorines and organophosphorus). These compounds were used as standards to generate calibration curves and estimate precisely their concentration in the tested samples using selected ion monitoring (SIM) mode. The results have shown the presence of an important quantity of pesticides that are no more used (banned) for decades for agriculture purposes but they are still used as veterinary drugs, such as lindane (0.2 ppm grape, 0.32 ppm tomato) and fenchlorphos (0.5 ppm grape). This survey should be routinely executed by scientists and concerned authorities to control pesticides circulation with their exact amounts in food and other environmental matrices as well as eventual contamination with another toxic element.
{"title":"Agricultural and Veterinary Pesticides Residues in Human Food","authors":"Latifa Khattabi, Moussa Mokhtari, M. Bouhenna, Ahmed Fellak, Mohamed Abu-Mustapha, Saleh Akkal, Feriel Sellam","doi":"10.2174/2213346110666230607150014","DOIUrl":"https://doi.org/10.2174/2213346110666230607150014","url":null,"abstract":"\u0000\u0000Expanding utilization of pesticides can provoke serious issues due to their biomagnification and persistent nature. Eventual contamination of fresh daily-consumed food by pesticide\u0000constitutes a human food security problem.\u0000\u0000\u0000\u0000The present investigation planned to check out whether the most hazardous pesticides could be\u0000found in a varied collection of wheat, vegetables and fruit, on the other hand, we attempted to know if\u0000some banned and no more commercialized pesticides could be even detected. Effectively, we have chosen\u0000to analyze wheat, potato, tomato, apple, peach and grape, so, after the extraction procedure of pesticides,\u0000we used gas chromatography-mass spectrometry (GC-MS) to identify some hazardous compounds (organochlorines and organophosphorus). These compounds were used as standards to generate calibration\u0000curves and estimate precisely their concentration in the tested samples using selected ion monitoring\u0000(SIM) mode.\u0000\u0000\u0000\u0000The results have shown the presence of an important quantity of pesticides that are no more used\u0000(banned) for decades for agriculture purposes but they are still used as veterinary drugs, such as lindane\u0000(0.2 ppm grape, 0.32 ppm tomato) and fenchlorphos (0.5 ppm grape).\u0000\u0000\u0000\u0000This survey should be routinely executed by scientists and concerned authorities to control\u0000pesticides circulation with their exact amounts in food and other environmental matrices as well as eventual contamination with another toxic element.\u0000","PeriodicalId":10856,"journal":{"name":"Current Green Chemistry","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48550354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.2174/221334611002230621163020
{"title":"Acknowledgements to Reviewers","authors":"","doi":"10.2174/221334611002230621163020","DOIUrl":"https://doi.org/10.2174/221334611002230621163020","url":null,"abstract":"","PeriodicalId":10856,"journal":{"name":"Current Green Chemistry","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136115850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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