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Biological Synthesis of Silver Nanoparticles and their Biomedical Activity: A Review 纳米银的生物合成及其生物医学活性研究进展
IF 2.2 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2021-12-17 DOI: 10.2174/2213346109666211217091042
S. Zafar, Aiman Zafar, F. Jabeen, M. Siddiq
Nanotechnology studies the various phenomena of physio-chemical procedures and biological properties for the generation of nanosized particles, and their rising challenges in the various sectors,like medicine, engineering, agriculture, electronic, and environmental studies. The nanosized particlesexhibit good anti-microbial, anti-inflammatory, cytotoxic, drug delivery, anti-parasitic, anti-coagulantand catalytic properties because of their unique dimensions with large surface area, chemical stabilityand higher binding density for the accumulation of various bio-constituents on their surfaces. Biologicalapproaches for the synthesis of silver nanoparticles (AgNPs) have been reviewed because it is an easyand single-step protocol and a viable substitute for the synthetic chemical-based procedures. Physicaland chemical approaches for the production of AgNPs are also mentioned herein. Biological synthesishas drawn attention because it is cost-effective, faster, non-pathogenic, environment-friendly, easy toscale-up for large-scale synthesis, and having no demand for usage of high pressure, energy, temperature, or noxious chemical ingredients, and safe for human therapeutic use. Therefore, the collaborationof nanomaterials with bio-green approaches could extend the utilization of biological and cytologicalproperties compatible with AgNPs. In this perspective, there is an immediate need to develop ecofriendly and biocompatible techniques, which strengthen efficacy against microbes and minimize toxicity for human cells. The present study introduces the biological synthesis of silver nanoparticles, andtheir potential biomedical applications have also been reviewed.
纳米技术研究产生纳米粒子的各种物理化学过程和生物特性的现象,以及它们在医学、工程、农业、电子和环境研究等各个领域面临的日益增长的挑战。纳米级颗粒具有良好的抗微生物、抗炎、细胞毒性、药物传递、抗寄生虫、抗凝血和催化性能,因为它们具有独特的尺寸,具有大的表面积、化学稳定性和更高的结合密度,可以在其表面积累各种生物成分。生物合成银纳米颗粒(AgNPs)的方法已经被回顾,因为它是一种简单的单步方案,是合成化学基础程序的可行替代品。本文还提到了生产AgNPs的物理和化学方法。生物合成因其具有成本效益高、速度快、无致病性、环境友好、易于大规模合成、不需要使用高压、能量、温度和有毒化学成分、对人体治疗安全等优点而备受关注。因此,纳米材料与生物绿色方法的合作可以扩展与AgNPs兼容的生物学和细胞学特性的利用。从这个角度来看,迫切需要开发生态友好和生物相容性的技术,以加强对微生物的功效并最大限度地减少对人体细胞的毒性。本文介绍了纳米银的生物合成方法,并对其潜在的生物医学应用进行了综述。
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引用次数: 0
On our way to fulfilling the twelve principles of green chemistry 在实现绿色化学十二项原则的道路上
IF 2.2 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2021-12-09 DOI: 10.2174/2213346108999211209111647
M. Sydnes
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引用次数: 0
Trends and Possibilities to Turn Industrial Organic Chemistry Greener 实现工业有机化学绿色化的趋势和可能性
IF 2.2 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2021-10-21 DOI: 10.2174/2213346108666211021161235
G. Keglevich
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引用次数: 0
Plant extract mediated synthesis of metal nanoparticles, their characterization and applications: A green approach 植物提取物介导的金属纳米粒子的合成、表征和应用:一种绿色方法
IF 2.2 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2021-09-01 DOI: 10.2174/2213346108666210901113852
S. Jha, A. Jha
Nowadays, nanoparticles are gaining enormous importance in a wide variety of disciplines due to their unambiguous physical and chemical properties. There are lots of physical and chemical approaches available for the synthesis of metal nanoparticles. But there are certain disadvantages associated with these methods, such as adsorption of hazardous toxins on the surface of the material, high capital investment, high manufacturing energy demand, etc., which make their effective implementation almost impossible. An alternative method of synthesizing nanoparticles to avoid the aforementioned disadvantages is to use different parts of the plant under aqueous conditions. Plant-mediated approach for the synthesis of nanoparticles is becoming increasingly popular due to its faster reaction rate, easily affordable, eco-friendly nature and rich diversity of plants. Chemical compositions of plant extracts are examined using the liquid chromatography-mass spectrometry technique. Noble metals such as Silver, Gold, Iron, Copper, Platinum, Zinc, Palladium, and their oxides are used for the fabrication of metal nanoparticles, due to their enormous potential applications. In a single-step green synthesis process, the phytochemical constituents which are present in plant extract reduce metal salts into metal nanoparticles. This article gives an overview of plant-mediated synthesized metal and metal oxide nanoparticles and their characterization by using different techniques, together with their properties and applications in numerous fields.
如今,纳米颗粒由于其明确的物理和化学性质,在各种学科中获得了巨大的重要性。有许多物理和化学方法可用于合成金属纳米颗粒。但这些方法也存在一些缺点,如有害毒素在材料表面的吸附、高资本投资、高制造能源需求等,使其几乎不可能有效实施。合成纳米颗粒以避免上述缺点的另一种方法是在含水条件下使用植物的不同部分。植物介导的纳米颗粒合成方法因其反应速度更快、价格实惠、环保和植物多样性丰富而越来越受欢迎。采用液相色谱-质谱技术对植物提取物的化学成分进行了检测。贵金属,如银、金、铁、铜、铂、锌、钯及其氧化物,由于其巨大的潜在应用,被用于制造金属纳米颗粒。在一步绿色合成过程中,植物提取物中存在的植物化学成分将金属盐还原为金属纳米颗粒。本文概述了植物介导合成的金属和金属氧化物纳米颗粒及其不同技术的表征,以及它们的性质和在许多领域的应用。
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引用次数: 2
Meet the Executive Guest Editor 这是执行客座编辑
IF 2.2 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2021-08-13 DOI: 10.2174/221334610802210813103454
Vitor S. C. de Andrade
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引用次数: 0
Green Synthesis of Five- and Six-membered N-heterocycles by Ultrasonic Irradiation in Aqueous Media 水介质中超声辐射绿色合成五元和六元N-杂环化合物
IF 2.2 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2021-04-23 DOI: 10.2174/2213346108666210423120316
T. C. Nogueira, M. D. de Souza
Five- and six-membered N-heterocyclic compounds play an important role in medicinalchemistry and the development of new drugs. There is a constant demand for the development of novelbiologically potent compounds, and there is also an increasing pressure to develop alternative andmore sustainable synthetic methodologies following the Green Chemistry principles. Thus, the presentreview aims to compile the latest progress in the use of ultrasound irradiation in water conditionsto mediate the synthesis of five- and six-membered N-heterocyclic compounds in an environmentallybenign manner.
五元和六元氮杂环化合物在药物化学和新药开发中发挥着重要作用。人们对开发新的生物活性化合物的需求不断增加,同时也面临着越来越大的压力,需要根据绿色化学原理开发替代的、更可持续的合成方法。因此,本文旨在综述在水条件下使用超声辐射以环境友好的方式介导合成五元和六元N-杂环化合物的最新进展。
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引用次数: 0
Commonly Used Disposing Methods for Waste Pesticides 废弃农药的常用处理方法
IF 2.2 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2021-04-19 DOI: 10.2174/2213346108666210419120506
E. Chmielewská
The starting of DDT production during World War II also signalized the beginning of avery rapid increase in pesticide use. Pesticides applied in the control of invertebrates are known asinsecticides. On the other hand, vertebrates are controlled by rodenticides, which are used for killingrodents etc.; moreover, avicides are applied to repel birds, and piscicides are used in fish control.Herbicides are the most important in agriculture and are used for plant cultivation, moreover, fungicidesare useful in killing fungi. Bactericides are used against bacteria, slimicides are used againstslime-causing organisms in water, and algicides against algae. Many pesticides which were used inagriculture in the last 30-40 years are no longer authorised and have been replaced by pesticides ona non-chemical basis. Currently, the aim of the REACH Regulation in the European Union is toprovide better protection for humans and the environment from possible chemical risks and to promotesustainable development. The European Chemicals Agency, established under this regulationand based in Helsinki, is responsible for managing the technical, scientific, and administrative aspectsof REACH and for ensuring consistency in its application (www.europarl.europa.eu). In orderto enhance the level of protection of human health and the environment, the same criteria for identifyinglabels for describing chemical hazards should be used throughout the EU and the world(www.europarl.europa.eu). This contribution briefly refers to the pesticides classification and theirmost commonly used detoxification.
第二次世界大战期间开始生产滴滴涕也标志着农药使用迅速增加的开始。用于控制无脊椎动物的杀虫剂被称为杀虫剂。另一方面,脊椎动物受到灭鼠剂的控制,灭鼠剂用于杀死啮齿动物等;此外,杀菌剂用于驱鸟,杀菌剂用于控制鱼类。除草剂在农业中是最重要的,用于植物栽培,此外,杀菌剂可用于杀死真菌。杀菌剂用于杀灭细菌,杀黏液剂用于杀灭水中引起黏液的生物,而杀藻剂用于杀灭藻类。过去30-40年间在农业中使用的许多农药已不再被批准使用,并已被非化学农药所取代。目前,欧盟REACH法规的目的是为人类和环境提供更好的保护,使其免受可能的化学品风险,并促进可持续发展。欧洲化学品管理局根据该法规成立,总部设在赫尔辛基,负责管理REACH的技术、科学和行政方面,并确保其应用的一致性(www.europarl.europa.eu)。为了提高对人类健康和环境的保护水平,应在整个欧盟和世界范围内使用相同的标准来识别描述化学品危害的标签(www.europarl.europa.eu)。本文简要介绍了农药的分类及其最常用的解毒方法。
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引用次数: 0
Meet Our Editorial Board Member 见见我们的编辑委员会成员
IF 2.2 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2021-02-16 DOI: 10.2174/221334610801210127164835
M. L. Di Gioia
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引用次数: 0
Preface 前言
IF 2.2 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2021-02-16 DOI: 10.2174/221334610801210128093628
G. Keglevich
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引用次数: 0
Organic Transformations by Following Green Credentials-Part 2 遵循绿色证书的有机转变第2部分
IF 2.2 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2021-02-16 DOI: 10.2174/221334610801210128093822
B. Banerjee
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引用次数: 1
期刊
Current Green Chemistry
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