Cryobiology最新文献

英文中文

Developing 3D vitrification for cat oocytes: Viability, maturation and actin pattern 发展猫卵母细胞的三维玻璃化：活力、成熟和肌动蛋白模式

IF 2.1 3区生物学 Q2 BIOLOGY

Cryobiology

Pub Date : 2025-12-01 DOI: 10.1016/j.cryobiol.2025.105356

Martina Colombo, Alessandra Mascaro, Jasmine Fusi, Alessandro Pecile, Gaia Cecilia Luvoni

引用次数: 0

Effect of ice recrystallization on membrane leakage studied in a liposome system 脂质体系统中冰重结晶对膜渗漏的影响

IF 2.1 3区生物学 Q2 BIOLOGY

Cryobiology

Pub Date : 2025-12-01 DOI: 10.1016/j.cryobiol.2025.105375

Dejia Liu , Harriëtte Oldenhof , Harald Sieme , Willem F. Wolkers

引用次数: 0

Can anhydrobiosis be used to preserve cells in a dried state? 在干燥状态下，可以用无水法来保存细胞吗？

IF 2.1 3区生物学 Q2 BIOLOGY

Cryobiology

Pub Date : 2025-12-01 DOI: 10.1016/j.cryobiol.2025.105372

Takahiro Kikawada

引用次数: 0

Permeability of the zebrafish embryo’s chorion for cryoprotectants DMSO and ethylene glycol 斑马鱼胚胎绒毛膜对低温保护剂二甲基亚砜和乙二醇的渗透性

IF 2.1 3区生物学 Q2 BIOLOGY

Cryobiology

Pub Date : 2025-12-01 DOI: 10.1016/j.cryobiol.2025.105361

Joachim Cobbaut , Adrian Covaci , Dries Knapen , Lucia Vergauwen , Ruth Appeltant , Peter E.J. Bols

引用次数: 0

Beyond larvae: Cryopreserving Mytilus galloprovincialis juveniles 幼体以外：超低温贮藏加洛省贻贝幼体

IF 2.1 3区生物学 Q2 BIOLOGY

Cryobiology

Pub Date : 2025-12-01 DOI: 10.1016/j.cryobiol.2025.105397

Alba Lagoa, Jesus Troncosoa, Estefanía Paredes

引用次数: 0

Advances in cryopreservation of embryos of the Mexican amphibian Ambystoma mexicanum as a conservation strategy 墨西哥两栖动物Ambystoma mexicanum胚胎低温保存研究进展

IF 2.1 3区生物学 Q2 BIOLOGY

Cryobiology

Pub Date : 2025-12-01 DOI: 10.1016/j.cryobiol.2025.105398

Erika Servin-Zamora, Montserrat Torres-Solis, Alicia Alcantar-Rodriguez, José Alfredo Medrano

引用次数: 0

Cryopreservation going digital - Using computational fluid dynamics to optimize formulations and methods 低温保存走向数字化——利用计算流体动力学优化配方和方法

IF 2.1 3区生物学 Q2 BIOLOGY

Cryobiology

Pub Date : 2025-12-01 DOI: 10.1016/j.cryobiol.2025.105369

Rafaela Neves , Andreia Duarte , Vitor Geraldes , Miguel A. Rodrigues

引用次数: 0

Enhanced prevention of cell death by hypothermic storage with propyl gallate 用没食子酸丙酯低温储存增强预防细胞死亡

IF 2.1 3区生物学 Q2 BIOLOGY

Cryobiology

Pub Date : 2025-11-28 DOI: 10.1016/j.cryobiol.2025.105562

Xiaodong Li , Ryan Chan , Xinglan Li , Qiunong Guan , Jingyi Li , Xiaowei Li , Haofeng Li , Shadan Li , Caigan Du

Current hypothermic preservation solutions are insufficient to prevent donor organ injury during hypothermic storage, which negatively impacts graft functional recovery and survival after transplantation. This study was to evaluate whether supplementation of the preservation solutions with antioxidant propyl gallates (PG) reduced cell injury during hypothermic storage and subsequently rewarming-reoxygenation or transplantation. Human cells and rat aorta were stored in University of Wisconsin (UW) or hyperbranched polyglycerol (HPG) solution supplemented with PG at 4 °C, followed by rewarming-reoxygenation with atmospheric O₂ at 37 °C and isotransplantation, respectively. Cell or tissue injury was measured by lactate dehydrogenase release, flow cytometric and histologic analyses. Here, we showed that PG supplementation significantly increased antioxidative activities of both UW and HPG solutions, and its concentrations for maximum protection of different human cells from hypothermic storage-induced cell death were estimated between 25 and 50 μM, which was also indicated by increased cell survival or decreased cell apoptosis during rewarming-reoxygenation. The PG cytoprotection was correlated with its inhibition of lipid peroxidation, prevention of mitochondrial dysfunction or an increase in ATP content. The enhanced cytoprotection of preservation solutions by PG supplementation was confirmed in hypothermic storage of rat aortas, indicated by less tissue damage and higher levels of tissue ATP during the hypothermic storage and less chronic injury after transplantation. In conclusion, cell injury during hypothermic storage and subsequently rewarming-reoxygenation was substantially prevented by the hypothermic preservation with PG, suggesting that PG is a promising antioxidant for hypothermic preservation of donor cells or organs in transplantation.

目前的低温保存解决方案不足以防止供体器官在低温保存过程中的损伤，这对移植后移植物功能的恢复和存活产生负面影响。本研究旨在评估在保存液中添加抗氧化剂没食子酸丙酯（PG）是否能减少低温储存和随后的复温-复氧或移植过程中的细胞损伤。人体细胞和大鼠主动脉分别保存在威斯康星大学（University of Wisconsin， UW）或添加PG的超支化聚甘油（hyperbranched polyglycerol， HPG）溶液中，4℃保存，37℃常压O2复氧，等移植。通过乳酸脱氢酶释放、流式细胞术和组织学分析检测细胞或组织损伤。在这里，我们发现PG的补充显著提高了UW和HPG溶液的抗氧化活性，并且其浓度在25 ~ 50 μM之间，可以最大限度地保护不同的人类细胞免受低温储存诱导的细胞死亡，这也表明在再加热-再氧化过程中细胞存活率增加或细胞凋亡减少。PG的细胞保护作用与其抑制脂质过氧化、防止线粒体功能障碍或增加ATP含量有关。在大鼠主动脉低温贮藏中，添加PG的保存液增强了细胞保护作用，表现为低温贮藏过程中组织损伤较小，组织ATP水平较高，移植后慢性损伤较小。综上所述，低温保存过程中的细胞损伤和随后的再加热-再氧化被PG大大防止，这表明PG是一种很有前途的低温保存供体细胞或移植器官的抗氧化剂。

{"title":"Enhanced prevention of cell death by hypothermic storage with propyl gallate","authors":"Xiaodong Li , Ryan Chan , Xinglan Li , Qiunong Guan , Jingyi Li , Xiaowei Li , Haofeng Li , Shadan Li , Caigan Du","doi":"10.1016/j.cryobiol.2025.105562","DOIUrl":"10.1016/j.cryobiol.2025.105562","url":null,"abstract":"<div><div>Current hypothermic preservation solutions <strong>are</strong> insufficient to prevent donor organ injury <strong>during hypothermic</strong> storage, which negatively impacts graft functional recovery and survival after transplantation. This study was to evaluate whether supplementation of the preservation solutions with antioxidant propyl gallates (PG) reduced cell injury during hypothermic storage and subsequently rewarming-reoxygenation or transplantation. Human cells and rat aorta were stored in University of Wisconsin (UW) or hyperbranched polyglycerol (HPG) solution supplemented with PG at 4 °C, followed by rewarming-reoxygenation with atmospheric O<sub>2</sub> at 37 °C and isotransplantation, respectively. Cell or tissue injury was measured by lactate dehydrogenase release, flow cytometric and histologic analyses. Here, we showed that PG supplementation significantly increased antioxidative activities of both UW and HPG solutions, and its concentrations for maximum protection of different human cells from hypothermic storage-induced cell death were estimated between 25 and 50 μM, which was also indicated by increased cell survival or decreased cell apoptosis during rewarming-reoxygenation. The PG cytoprotection was correlated with its inhibition of lipid peroxidation, prevention of mitochondrial dysfunction or an increase in ATP content. The enhanced cytoprotection of preservation solutions by PG supplementation was confirmed in hypothermic storage of rat aortas, indicated by less tissue damage and higher levels of tissue ATP during the hypothermic storage and less chronic injury after transplantation. In c<strong>onclusion, cell injury during hypothermic</strong> storage and subsequently rewarming-reoxygenation was substantially prevented by the hypothermic preservation with PG, suggesting that PG is a promising antioxidant for hypothermic preservation of donor cells or organs in transplantation.</div></div>","PeriodicalId":10897,"journal":{"name":"Cryobiology","volume":"122 ","pages":"Article 105562"},"PeriodicalIF":2.1,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145615983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of free rosmarinic acid and rosmarinic acid-loaded chitosan nanoparticles in buffalo sperm cryopreservation: Impacts on sperm quality, functionality, and fertility potential 游离迷迭香酸和载迷迭香酸壳聚糖纳米颗粒在水牛精子冷冻保存中的评价：对精子质量、功能和生育潜力的影响

IF 2.1 3区生物学 Q2 BIOLOGY

Cryobiology

Pub Date : 2025-11-21 DOI: 10.1016/j.cryobiol.2025.105548

Fatma Mohsen Shalaby , Ohoud Ali Saeed Alghamdi , Ali Ali El-Raghi , Mahmoud A.E. Hassan , Walaa M. Essawi , Amany Omar Elrefaie , Amal El-Sayed Abd El Hady , Kandil Abd El Hai Attia

The aim of this study was to assess the effects of incorporating either free rosmarinic acid (RA) or RA-loaded chitosan nanoparticles (RA-CHNPs) into a buffalo semen extender on various parameters, including semen quality, antioxidant capacity, expression of apoptotic genes, semen microbiota, ultra-structural alterations, and fertility outcomes of cryopreserved buffalo sperm. Semen samples were collected from five healthy, fertile Egyptian buffalo bulls (Bubalus bubalis), aged 5–6 years, using the artificial vagina technique. The ejaculates were cryopreserved in a Tris-based extender supplemented with 100 μg/mL of either RA or RA-CHNPs, alongside a control group without antioxidant supplementation. Supplementing the cryopreservation extender with 100 μg/mL RA-CHNPs significantly improved sperm viability, progressive motility, membrane integrity, and kinematic parameters. Additionally, it significantly enhanced the activity of major antioxidant enzymes and markedly reduced levels of hydrogen peroxide, malondialdehyde, nitric oxide, and semen microbiota counts compared to the control group (p < 0.05). Furthermore, RA-CHNPs treatment significantly modulated the expression of apoptosis-involved genes, with reduced expression of caspase-3 and Bax and increased Bcl-2 expression. Transmission electron microscopy confirmed that RA-CHNPs helped preserve the ultra-structural integrity of spermatozoa, particularly the acrosome and plasma membrane. Notably, pregnancy rates increased by 19 % in buffalo cows inseminated with RA-CHNPs-treated semen compared to those inseminated with supplemented semen (p = 0.0157). In conclusion, loading rosmarinic acid onto chitosan nanoparticles enhanced its stability, water solubility, and bioavailability, ultimately improving its effectiveness in the semen freezing extender. The addition of 100 μg of RA-CHNPs significantly improved post-thaw sperm quality.

本研究的目的是评估将游离迷迭香酸（RA）或负载RA的壳聚糖纳米颗粒（RA- chnps）加入水牛精液填充剂对水牛精液质量、抗氧化能力、凋亡基因表达、精液微生物群、超结构改变和低温保存水牛精子生育结果等参数的影响。采用人工阴道技术，采集了5头5-6岁健康、可育的埃及水牛（Bubalus bubalis）的精液样本。将射精液冷冻保存在含有100 μg/mL RA或RA- chnps的tris扩展液中，与不添加抗氧化剂的对照组一起保存。在低温保存扩展剂中添加100 μg/mL RA-CHNPs可显著提高精子活力、渐进式运动性、膜完整性和运动学参数。此外，与对照组相比，它显著提高了主要抗氧化酶的活性，显著降低了过氧化氢、丙二醛、一氧化氮水平和精液微生物群计数（p < 0.05）。此外，RA-CHNPs处理显著调节凋亡相关基因的表达，降低caspase-3和Bax的表达，增加Bcl-2的表达。透射电镜证实，RA-CHNPs有助于保持精子的超结构完整性，特别是顶体和质膜。值得注意的是，与补充了ra - chnps的精液的水牛相比，用ra - chnps处理的精液受精的水牛的受孕率提高了19% （p = 0.0157）。综上所述，壳聚糖纳米粒负载迷迭香酸增强了其稳定性、水溶性和生物利用度，最终提高了其在精液冷冻剂中的应用效果。添加100 μg RA-CHNPs显著提高解冻后精子质量。

{"title":"Evaluation of free rosmarinic acid and rosmarinic acid-loaded chitosan nanoparticles in buffalo sperm cryopreservation: Impacts on sperm quality, functionality, and fertility potential","authors":"Fatma Mohsen Shalaby , Ohoud Ali Saeed Alghamdi , Ali Ali El-Raghi , Mahmoud A.E. Hassan , Walaa M. Essawi , Amany Omar Elrefaie , Amal El-Sayed Abd El Hady , Kandil Abd El Hai Attia","doi":"10.1016/j.cryobiol.2025.105548","DOIUrl":"10.1016/j.cryobiol.2025.105548","url":null,"abstract":"<div><div>The aim of this study was to assess the effects of incorporating either free rosmarinic acid (RA) or RA-loaded chitosan nanoparticles (RA-CHNPs) into a buffalo semen extender on various parameters, including semen quality, antioxidant capacity, expression of apoptotic genes, semen microbiota, ultra-structural alterations, and fertility outcomes of cryopreserved buffalo sperm. Semen samples were collected from five healthy, fertile Egyptian buffalo bulls (<em>Bubalus bubalis</em>), aged 5–6 years, using the artificial vagina technique. The ejaculates were cryopreserved in a Tris-based extender supplemented with 100 μg/mL of either RA or RA-CHNPs, alongside a control group without antioxidant supplementation. Supplementing the cryopreservation extender with 100 μg/mL RA-CHNPs significantly improved sperm viability, progressive motility, membrane integrity, and kinematic parameters. Additionally, it significantly enhanced the activity of major antioxidant enzymes and markedly reduced levels of hydrogen peroxide, malondialdehyde, nitric oxide, and semen microbiota counts compared to the control group (p < 0.05). Furthermore, RA-CHNPs treatment significantly modulated the expression of apoptosis-involved genes, with reduced expression of caspase-3 and Bax and increased Bcl-2 expression. Transmission electron microscopy confirmed that RA-CHNPs helped preserve the ultra-structural integrity of spermatozoa, particularly the acrosome and plasma membrane. Notably, pregnancy rates increased by 19 % in buffalo cows inseminated with RA-CHNPs-treated semen compared to those inseminated with supplemented semen (p = 0.0157). In conclusion, loading rosmarinic acid onto chitosan nanoparticles enhanced its stability, water solubility, and bioavailability, ultimately improving its effectiveness in the semen freezing extender. The addition of 100 μg of RA-CHNPs significantly improved post-thaw sperm quality.</div></div>","PeriodicalId":10897,"journal":{"name":"Cryobiology","volume":"122 ","pages":"Article 105548"},"PeriodicalIF":2.1,"publicationDate":"2025-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145570837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a new freeze-drying protection system for potential probiotic Enterococcus faecalis L118 and evaluation of its storage stability 潜在益生菌粪肠球菌L118冻干保护系统的研制及其贮存稳定性评价

IF 2.1 3区生物学 Q2 BIOLOGY

Cryobiology

Pub Date : 2025-11-21 DOI: 10.1016/j.cryobiol.2025.105549

Longhao Wang , Zekai Wang , Chengcai Zhu, Deqiang Yan, Yuan Cheng, Kang Yan, Shaojun He

The purpose of this study was to investigate the freeze-drying protective effect of cold stress and arginine on Enterococcus faecalis L118 and to develop a new freeze-drying protection system in combination with glycerol and skim milk. The freeze-drying protection effect of cold stress and arginine on E. faecalis L118 was evaluated using one-way ANOVA and response surface methodology (RSM), and the freeze-drying protection system was optimized. Subsequently, the protective mechanism and efficacy of the optimized system were further assessed via cell membrane integrity analysis, storage stability tests, probiotic property assays, and RT-qPCR. In this study, cold stress on E. faecalis L118 before freeze-drying and arginine as a cryoprotectant significantly enhanced its survival rate. The optimal protection system was optimized via RSM to consist of cold stress at 8 °C for 8 h, 1.5 % arginine, 10.4 % skim milk, and 9.8 % glycerol, and the survival rate of E. faecalis L118 achieved under this system was 87.90 ± 1.28 %. The E. faecalis L118 treated with the optimal protection system had relatively high storage stability at −20 °C and could maintain the cell membrane integrity and probiotic properties of E. faecalis L118. RT-qPCR results indicated that cold stress significantly upregulated (P < 0.05) the expression of atpA, plsX, luxS, and SOD genes, while arginine upregulated (P < 0.05) atpA, cspC, LDH1, FabH, FabF, plsX, and mprF2 genes. All genes in the optimal protection system were upregulated (P < 0.05). Our study demonstrated the protective effects of cold stress and arginine on E. faecalis L118 during freeze-drying and established a novel freeze-drying protective system, providing a theoretical basis for the preservation and industrial-scale production of E. faecalis L118.

本研究旨在探讨冷胁迫和精氨酸对粪肠球菌L118的冻干保护作用，并与甘油和脱脂乳联合开发一种新的冻干保护体系。采用单因素方差分析和响应面法（RSM）评价冷胁迫和精氨酸对粪肠杆菌L118的冻干保护效果，并对冻干保护体系进行优化。随后，通过细胞膜完整性分析、储存稳定性测试、益生菌特性测试和RT-qPCR进一步评估优化后体系的保护机制和效果。在本研究中，冷冻干燥前对粪肠球菌L118进行冷胁迫，并添加精氨酸作为冷冻保护剂，可显著提高其存活率。通过RSM优化了8℃低温胁迫8 h、精氨酸1.5%、脱脂牛奶10.4%、甘油9.8%的保护体系，该保护体系下粪肠球菌L118的存活率为87.90±1.28%。经最佳保护体系处理的粪肠球菌L118在- 20℃下具有较高的贮藏稳定性，能保持粪肠球菌L118的细胞膜完整性和益生菌特性。RT-qPCR结果显示，冷胁迫显著上调atpA、plsX、luxS和SOD基因的表达（P < 0.05），精氨酸上调atpA、cspC、LDH1、FabH、FabF、plsX和mprF2基因的表达（P < 0.05）。最佳保护系统中所有基因均表达上调（P < 0.05）。本研究验证了冷胁迫和精氨酸对粪肠球菌L118冷冻干燥过程的保护作用，建立了一种新型的冷冻干燥保护体系，为粪肠球菌L118的保存和工业化生产提供了理论依据。

{"title":"Development of a new freeze-drying protection system for potential probiotic Enterococcus faecalis L118 and evaluation of its storage stability","authors":"Longhao Wang , Zekai Wang , Chengcai Zhu, Deqiang Yan, Yuan Cheng, Kang Yan, Shaojun He","doi":"10.1016/j.cryobiol.2025.105549","DOIUrl":"10.1016/j.cryobiol.2025.105549","url":null,"abstract":"<div><div>The purpose of this study was to investigate the freeze-drying protective effect of cold stress and arginine on <em>Enterococcus faecalis</em> L118 and to develop a new freeze-drying protection system in combination with glycerol and skim milk. The freeze-drying protection effect of cold stress and arginine on <em>E. faecalis</em> L118 was evaluated using one-way ANOVA and response surface methodology (RSM), and the freeze-drying protection system was optimized. Subsequently, the protective mechanism and efficacy of the optimized system were further assessed via cell membrane integrity analysis, storage stability tests, probiotic property assays, and RT-qPCR. In this study, cold stress on <em>E. faecalis</em> L118 before freeze-drying and arginine as a cryoprotectant significantly enhanced its survival rate. The optimal protection system was optimized via RSM to consist of cold stress at 8 °C for 8 h, 1.5 % arginine, 10.4 % skim milk, and 9.8 % glycerol, and the survival rate of <em>E. faecalis</em> L118 achieved under this system was 87.90 ± 1.28 %. The <em>E. faecalis</em> L118 treated with the optimal protection system had relatively high storage stability at −20 °C and could maintain the cell membrane integrity and probiotic properties of <em>E. faecalis</em> L118. RT-qPCR results indicated that cold stress significantly upregulated (<em>P</em> < 0.05) the expression of <em>atpA</em>, <em>plsX</em>, <em>luxS</em>, and <em>SOD</em> genes, while arginine upregulated (<em>P</em> < 0.05) <em>atpA</em>, <em>cspC</em>, <em>LDH1</em>, <em>FabH</em>, <em>FabF</em>, <em>plsX</em>, and <em>mprF2</em> genes. All genes in the optimal protection system were upregulated (<em>P</em> < 0.05). Our study demonstrated the protective effects of cold stress and arginine on <em>E. faecalis</em> L118 during freeze-drying and established a novel freeze-drying protective system, providing a theoretical basis for the preservation and industrial-scale production of <em>E. faecalis</em> L118.</div></div>","PeriodicalId":10897,"journal":{"name":"Cryobiology","volume":"122 ","pages":"Article 105549"},"PeriodicalIF":2.1,"publicationDate":"2025-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145570838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

首页上一页

下一页尾页

类型

全部化学•材料生命科学医学物理工程技术环境•农林材料科学地球科学法学管理学化学环境科学与生态学计算机科学教育学经济学农林科学人文科学生物学数学物理与天体物理心理学综合性期刊其他工业工程理学历史学农学文学信息工程

数据库

全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley

期刊

Cryobiology

全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.

﹀