Вера Алексеевна Скворцова, Татьяна Эдуардовна Боровик, Татьяна Владимировна Бушуева, Н. Г. Звонкова, Ольга Леонидовна Лукоянова, Елена Александровна Рославцева, Ирина Анатольевна Гусева
The article presents modern, scientifically substantiated approaches to the introduction of complementary feeding in healthy breastfed infants as well as in infants with overweight and various diseases — atopic dermatitis (food allergy), protein-energy deficiency in the context of chronic cardiovascular insufficiency syndrome, neurological disorders, celiac disease. The peculiarities of various complementary foods are demonstrated in clinical examples.
{"title":"ПРИКОРМ, ОСОБЕННОСТИ ВВЕДЕНИЯ. КЛИНИЧЕСКИЕ СЛУЧАИ","authors":"Вера Алексеевна Скворцова, Татьяна Эдуардовна Боровик, Татьяна Владимировна Бушуева, Н. Г. Звонкова, Ольга Леонидовна Лукоянова, Елена Александровна Рославцева, Ирина Анатольевна Гусева","doi":"10.15690/VSP.V16I4.1777","DOIUrl":"https://doi.org/10.15690/VSP.V16I4.1777","url":null,"abstract":"The article presents modern, scientifically substantiated approaches to the introduction of complementary feeding in healthy breastfed infants as well as in infants with overweight and various diseases — atopic dermatitis (food allergy), protein-energy deficiency in the context of chronic cardiovascular insufficiency syndrome, neurological disorders, celiac disease. The peculiarities of various complementary foods are demonstrated in clinical examples.","PeriodicalId":10919,"journal":{"name":"Current Paediatrics","volume":"89 1","pages":"304-313"},"PeriodicalIF":0.0,"publicationDate":"2017-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78984710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ольга Андреевна Клочкова, Алексей Львович Куренков, Н. В. Журкова, К. В. Савостьянов, И. С. Жанин, А. М. Мамедьяров, И. М. Тардова
Autosomal recessive peripheral neuropathy with neuromyotonia (ARAN-NM) is a relatively newly described disease associated with mutations in the HINT1 gene. It accounts for a significant part of the poorly differentiated forms of axonal polyneuropathies. We present the first in Russia description of the genetically confirmed case of ARAN-NM in a boy aged 14 years and 11 months without the hereditary-tainted anamnesis. On presentation, the patient experienced progressive distal muscular weakness, asymmetric foot deformity, gait disorders and minimal manifestations of neuromyotonia (stiffness in the fingers). During examination, we detected an increase in the level of creatine phosphokinase up to 635 U/l, a disturbance of conduction of motor and, to a lesser extent, sensory fibers of the peripheral nerves (according to the stimulation electromyography, EMG), denervation-reinnervation changes, single positive acute waves, fibrillation potentials, complex repeated discharge (according to the data of needle EMG). In the study of exome, a homozygous mutation c.110G>C, p.R37P was determined in exon 01 of the HINT1 gene, which confirmed the presence of ARAN-NM. A molecular-genetic examination of the patient's immediate relatives was carried out. The described case is compared with literature data. An overview of currently available information on ARAN-NM is provided. Diagnostic criteria of the disease are presented.
{"title":"АУТОСОМНО-РЕЦЕССИВНАЯ ПЕРИФЕРИЧЕСКАЯ НЕЙРОПАТИЯ С НЕЙРОМИОТОНИЕЙ (ARAN-NM): ОПИСАНИЕ КЛИНИЧЕСКОГО СЛУЧАЯ, ПОДТВЕРЖДЕННОГО МУТАЦИЕЙ В ГЕНЕ HINT1","authors":"Ольга Андреевна Клочкова, Алексей Львович Куренков, Н. В. Журкова, К. В. Савостьянов, И. С. Жанин, А. М. Мамедьяров, И. М. Тардова","doi":"10.15690/VSP.V16I4.1780","DOIUrl":"https://doi.org/10.15690/VSP.V16I4.1780","url":null,"abstract":"Autosomal recessive peripheral neuropathy with neuromyotonia (ARAN-NM) is a relatively newly described disease associated with mutations in the HINT1 gene. It accounts for a significant part of the poorly differentiated forms of axonal polyneuropathies. We present the first in Russia description of the genetically confirmed case of ARAN-NM in a boy aged 14 years and 11 months without the hereditary-tainted anamnesis. On presentation, the patient experienced progressive distal muscular weakness, asymmetric foot deformity, gait disorders and minimal manifestations of neuromyotonia (stiffness in the fingers). During examination, we detected an increase in the level of creatine phosphokinase up to 635 U/l, a disturbance of conduction of motor and, to a lesser extent, sensory fibers of the peripheral nerves (according to the stimulation electromyography, EMG), denervation-reinnervation changes, single positive acute waves, fibrillation potentials, complex repeated discharge (according to the data of needle EMG). In the study of exome, a homozygous mutation c.110G>C, p.R37P was determined in exon 01 of the HINT1 gene, which confirmed the presence of ARAN-NM. A molecular-genetic examination of the patient's immediate relatives was carried out. The described case is compared with literature data. An overview of currently available information on ARAN-NM is provided. Diagnostic criteria of the disease are presented.","PeriodicalId":10919,"journal":{"name":"Current Paediatrics","volume":"1 1","pages":"326-333"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84518645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
З. А. Алачева, О. Б. Рыбалка, Татьяна Владимировна Куличенко
Every year, an increase in the incidence of enterovirus infection is registered everywhere, including Coxsackie viruses. Parents of sick children are often very uneasy considering these viruses to be extremely dangerous and the disease to be severe one, with possible adverse consequences. The situation is exacerbated by many mass media that inform about the epidemic of Coxsackie virus, which causes a terrible disease. The article gives main characteristics of microorganisms, modes of infection, clinical manifestations of enterovirus infections as well as measures for prevention and treatment.
{"title":"ВСЕМ СПАСАТЬСЯ ОТ КОКСАКИ?! ИЛИ У СТРАХА ГЛАЗА ВЕЛИКИ","authors":"З. А. Алачева, О. Б. Рыбалка, Татьяна Владимировна Куличенко","doi":"10.15690/VSP.V16I4.1774","DOIUrl":"https://doi.org/10.15690/VSP.V16I4.1774","url":null,"abstract":"Every year, an increase in the incidence of enterovirus infection is registered everywhere, including Coxsackie viruses. Parents of sick children are often very uneasy considering these viruses to be extremely dangerous and the disease to be severe one, with possible adverse consequences. The situation is exacerbated by many mass media that inform about the epidemic of Coxsackie virus, which causes a terrible disease. The article gives main characteristics of microorganisms, modes of infection, clinical manifestations of enterovirus infections as well as measures for prevention and treatment.","PeriodicalId":10919,"journal":{"name":"Current Paediatrics","volume":"19 1","pages":"286-290"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81827198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
А. В. Карасёва, Екатерина Иосифовна Алексеева, Т. М. Дворяковская
The article presents a case of polyarticular juvenile idiopathic arthritis resistant to methotrexate therapy and nonsteroidal antiinflammatory drugs. The child was prescribed a tumor necrosis factor inhibitor etanercept at a dose of 0.4 mg/kg body weight2 times/week. The treatment with etanercept induced remission of the disease, ensured the function restoration in the joints. The predictors of a good response to etanercept were the younger age, the short course of the disease, the use of a small number of immunosuppressants before prescription of etanercept, the absence of concomitant use of glucocorticosteroids, and the absence of uveitis.
{"title":"ОПЫТ УСПЕШНОГО ПРИМЕНЕНИЯ ЭТАНЕРЦЕПТА У ПАЦИЕНТКИ С ПОЛИАРТИКУЛЯРНЫМ ВАРИАНТОМ ЮВЕНИЛЬНОГО ИДИОПАТИЧЕСКОГО АРТРИТА С ОБЗОРОМ ПРЕДИКТОРОВ ХОРОШЕГО ОТВЕТА НА ПРОВОДИМУЮ ТЕРАПИЮ","authors":"А. В. Карасёва, Екатерина Иосифовна Алексеева, Т. М. Дворяковская","doi":"10.15690/VSP.V16I4.1779","DOIUrl":"https://doi.org/10.15690/VSP.V16I4.1779","url":null,"abstract":"The article presents a case of polyarticular juvenile idiopathic arthritis resistant to methotrexate therapy and nonsteroidal antiinflammatory drugs. The child was prescribed a tumor necrosis factor inhibitor etanercept at a dose of 0.4 mg/kg body weight2 times/week. The treatment with etanercept induced remission of the disease, ensured the function restoration in the joints. The predictors of a good response to etanercept were the younger age, the short course of the disease, the use of a small number of immunosuppressants before prescription of etanercept, the absence of concomitant use of glucocorticosteroids, and the absence of uveitis.","PeriodicalId":10919,"journal":{"name":"Current Paediatrics","volume":"80 1","pages":"321-325"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73850779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background. Body weight gain and growth retardation are common side effects of prolonged glucocorticosteroid therapy in children. Time for the appearance and elimination of glucocorticosteroid obesity as well as growth disorders require further investigations. Objective . Our aim was to study the relationship between glucocorticosteroid therapy and changes in physical development indices of children with steroid-sensitive nephrotic syndrome (SSNS). Methods. We carried out a retrospective study of case records of patients with SSNS hospitalized in 2011–2014. Treatment of children was carried out in accordance with the Federal Clinical Guidelines. The Z-score (ANTHRO Plus) was determined for body length (height), body weight, body mass index and correlation of physical development indices with a cumulative dose and duration of glucocorticosteroid therapy. Results. We analyzed data on the treatment of 31 children, 18 of them received glucocorticosteroids for 6 months (Group 1), 13 of them did not receive glucocorticosteroids 6 months (Group 2). The Z-score of body weight in children in these groups was 1.64 ± 1.54 and 0.05 ± 1.19 (p = 0.004), Z-score of body mass index was 1.85 ± 1.64 and -0.54 ± 1.14, respectively (p < 0.001). Excess body weight and obesity were only observed in children of Group 1 (in 6 and 9, respectively). The Z-score of the body length of patients in groups 1 and 2 were comparable and did not differ from normal values (0.34 ± 1.08 and 0.52 ± 1.12, respectively, p = 0.655). Correlation of Z-score values of the body length and cumulative doses of glucocorticosteroids was noted (r = -0.87, p < 0.001). Conclusion. Long-term (at least 6 months) glucocorticosteroid intake is associated with the development of overweight and obesity in most children with SSNS. In patients who did not use hormonal drugs for 6 months, normal body weight values were recorded. The height of children with SSNS was within the range of normal values.
{"title":"ГЛЮКОКОРТИКОСТЕРОИДНАЯ ТЕРАПИЯ И ФИЗИЧЕСКОЕ РАЗВИТИЕ ДЕТЕЙ СО СТЕРОИДЧУВСТВИТЕЛЬНЫМ НЕФРОТИЧЕСКИМ СИНДРОМОМ: РЕЗУЛЬТАТЫ РЕТРОСПЕКТИВНОГО ИССЛЕДОВАНИЯ","authors":"Ольга Александровна Жданова","doi":"10.15690/VSP.V16I4.1775","DOIUrl":"https://doi.org/10.15690/VSP.V16I4.1775","url":null,"abstract":"Background. Body weight gain and growth retardation are common side effects of prolonged glucocorticosteroid therapy in children. Time for the appearance and elimination of glucocorticosteroid obesity as well as growth disorders require further investigations. Objective . Our aim was to study the relationship between glucocorticosteroid therapy and changes in physical development indices of children with steroid-sensitive nephrotic syndrome (SSNS). Methods. We carried out a retrospective study of case records of patients with SSNS hospitalized in 2011–2014. Treatment of children was carried out in accordance with the Federal Clinical Guidelines. The Z-score (ANTHRO Plus) was determined for body length (height), body weight, body mass index and correlation of physical development indices with a cumulative dose and duration of glucocorticosteroid therapy. Results. We analyzed data on the treatment of 31 children, 18 of them received glucocorticosteroids for 6 months (Group 1), 13 of them did not receive glucocorticosteroids 6 months (Group 2). The Z-score of body weight in children in these groups was 1.64 ± 1.54 and 0.05 ± 1.19 (p = 0.004), Z-score of body mass index was 1.85 ± 1.64 and -0.54 ± 1.14, respectively (p < 0.001). Excess body weight and obesity were only observed in children of Group 1 (in 6 and 9, respectively). The Z-score of the body length of patients in groups 1 and 2 were comparable and did not differ from normal values (0.34 ± 1.08 and 0.52 ± 1.12, respectively, p = 0.655). Correlation of Z-score values of the body length and cumulative doses of glucocorticosteroids was noted (r = -0.87, p < 0.001). Conclusion. Long-term (at least 6 months) glucocorticosteroid intake is associated with the development of overweight and obesity in most children with SSNS. In patients who did not use hormonal drugs for 6 months, normal body weight values were recorded. The height of children with SSNS was within the range of normal values.","PeriodicalId":10919,"journal":{"name":"Current Paediatrics","volume":"74 1","pages":"291-296"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76477554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
А. С. Полякова, М. БакрадзеД., Владимир Кириллович Таточенко, Диана Джансуховна Гадлия
Considering the colossal frequency of infectious diseases among children, pediatricians face the task not only to cure the patient but also to do this as soon as possible with an individual approach to each child. One of the main aspects of diagnosis in febrile children is the differentiation of a bacterial infection from viral one in order to assign timely antibiotic therapy to one patient and to prevent excessive assignment to others. In addition, an important point is to identify the category of patients with a severe bacterial infection, which requires the most attention. The article reveals the main points of a differential diagnosis of bacterial and viral infections, considering clinical symptoms and laboratory parameters: the concentration of procalcitonin, C-reactive protein, and leukocytes. The limits of procalcitonin values for various nosological forms and the possibility of their use in terms of the appointment, continuation or replacement of antibacterial therapy in pediatric practice are described.
{"title":"ДИАГНОСТИЧЕСКАЯ ЦЕННОСТЬ ОПРЕДЕЛЕНИЯ УРОВНЯ ПРОКАЛЬЦИТОНИНА В ПРАКТИКЕ ИНФЕКЦИОНИСТА","authors":"А. С. Полякова, М. БакрадзеД., Владимир Кириллович Таточенко, Диана Джансуховна Гадлия","doi":"10.15690/VSP.V16I4.1781","DOIUrl":"https://doi.org/10.15690/VSP.V16I4.1781","url":null,"abstract":"Considering the colossal frequency of infectious diseases among children, pediatricians face the task not only to cure the patient but also to do this as soon as possible with an individual approach to each child. One of the main aspects of diagnosis in febrile children is the differentiation of a bacterial infection from viral one in order to assign timely antibiotic therapy to one patient and to prevent excessive assignment to others. In addition, an important point is to identify the category of patients with a severe bacterial infection, which requires the most attention. The article reveals the main points of a differential diagnosis of bacterial and viral infections, considering clinical symptoms and laboratory parameters: the concentration of procalcitonin, C-reactive protein, and leukocytes. The limits of procalcitonin values for various nosological forms and the possibility of their use in terms of the appointment, continuation or replacement of antibacterial therapy in pediatric practice are described.","PeriodicalId":10919,"journal":{"name":"Current Paediatrics","volume":"34 1","pages":"334-341"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72762523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
М. Л. Травина, А. Г. Попов, С. А. Попов, Е. В. Куликова
Preservation and prolongation of the lactation period is not only a guarantee of the child's full physical and mental development but also one of the most important methods for reducing the risk of developing breast cancer. Problems with the mammary gland nipple in a woman in the early postnatal period lead to a refusal of lactation. We carried out a retrospective analysis (period from 2010 to 2016) of the causes of traumatizing mammary gland nipples in the early postnatal period in 172 women (mean age 29.1 ± 4.3 years). Methods of prevention and treatment of nipple injuries in the early postnatal period have been offered for the lactation period prolongation.
{"title":"ПРОФИЛАКТИКА ТРЕЩИН СОСКА МОЛОЧНОЙ ЖЕЛЕЗЫ В РАННИЙ ПОСЛЕРОДОВЫЙ ПЕРИОД","authors":"М. Л. Травина, А. Г. Попов, С. А. Попов, Е. В. Куликова","doi":"10.15690/VSP.V16I4.1776","DOIUrl":"https://doi.org/10.15690/VSP.V16I4.1776","url":null,"abstract":"Preservation and prolongation of the lactation period is not only a guarantee of the child's full physical and mental development but also one of the most important methods for reducing the risk of developing breast cancer. Problems with the mammary gland nipple in a woman in the early postnatal period lead to a refusal of lactation. We carried out a retrospective analysis (period from 2010 to 2016) of the causes of traumatizing mammary gland nipples in the early postnatal period in 172 women (mean age 29.1 ± 4.3 years). Methods of prevention and treatment of nipple injuries in the early postnatal period have been offered for the lactation period prolongation.","PeriodicalId":10919,"journal":{"name":"Current Paediatrics","volume":"21 1","pages":"297-303"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84162865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Namazova-Baranova, M. V. Fedoseenko, E. Vishneva, V. K. Tatochenko, L. Selimzianova, D. Chemakina
The article reviews the results of scientific researches published over the past few years that confirm the significant socioeconomic burden of rotavirus infection and its significant contribution to the morbidity and mortality of the world’s children’s population. The authors presented evidence of the effectiveness of immunization in the routine schedule of preventive vaccinations of infants in both developed and developing countries. A significant reduction in mortality and admissions due to severe forms of rotavirus gastroenteritis during the first years of introduction of rotavirus vaccination was shown, which marked a positive trend in the development of health care.
{"title":"ВАКЦИНАЦИЯ ПРОТИВ РОТАВИРУСНОЙ ИНФЕКЦИИ: 10-ЛЕТНИЙ МИРОВОЙ ОПЫТ УСПЕШНОГО ПРИМЕНЕНИЯ","authors":"L. Namazova-Baranova, M. V. Fedoseenko, E. Vishneva, V. K. Tatochenko, L. Selimzianova, D. Chemakina","doi":"10.15690/VSP.V16I4.1773","DOIUrl":"https://doi.org/10.15690/VSP.V16I4.1773","url":null,"abstract":"The article reviews the results of scientific researches published over the past few years that confirm the significant socioeconomic burden of rotavirus infection and its significant contribution to the morbidity and mortality of the world’s children’s population. The authors presented evidence of the effectiveness of immunization in the routine schedule of preventive vaccinations of infants in both developed and developing countries. A significant reduction in mortality and admissions due to severe forms of rotavirus gastroenteritis during the first years of introduction of rotavirus vaccination was shown, which marked a positive trend in the development of health care.","PeriodicalId":10919,"journal":{"name":"Current Paediatrics","volume":"28 1","pages":"273-285"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78803306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Екатерина Иосифовна Алексеева, Т. М. Дворяковская, Рина Валериановна Денисова, О. Л. Ломакина, А. В. Карасёва
The article presents a case of a severe progressive course of polyarticular juvenile idiopathic arthritis, debuting at an early age, refractory to the therapy with methotrexate, cyclosporine, and glucocorticosteroids. A clinical example demonstrates that switching to the second TNF inhibitor in the case of developing secondary resistance to the first drug from this group provides restoration of the therapeutic effect and is not accompanied by serious adverse events. Six months after switching to adalimumab, due to the «escape» of the effect of etanercept, the inflammatory changes in the patient were reversed; the volume of movements in the joints increased, and the laboratory parameters of the disease activity were normalized. After 1 year, there was a remission of the disease. The child managed to completely eliminate glucocorticosteroids for oral ingestion. The duration of the joint syndrome remission was 3 years. Adverse events were not serious and did not become a basis for drug withdrawal.
{"title":"ОПЫТ ПЕРЕКЛЮЧЕНИЯ НА ВТОРОЙ ИНГИБИТОР TNF ПАЦИЕНТКИ С ТЯЖЕЛЫМ ТЕЧЕНИЕМ ЮНОШЕСКОГО ПОЛИАРТРИТА И РЕЗИСТЕНТНОСТЬЮ К ПЕРВОМУ TNF-БЛОКАТОРУ1","authors":"Екатерина Иосифовна Алексеева, Т. М. Дворяковская, Рина Валериановна Денисова, О. Л. Ломакина, А. В. Карасёва","doi":"10.15690/VSP.V16I4.1778","DOIUrl":"https://doi.org/10.15690/VSP.V16I4.1778","url":null,"abstract":"The article presents a case of a severe progressive course of polyarticular juvenile idiopathic arthritis, debuting at an early age, refractory to the therapy with methotrexate, cyclosporine, and glucocorticosteroids. A clinical example demonstrates that switching to the second TNF inhibitor in the case of developing secondary resistance to the first drug from this group provides restoration of the therapeutic effect and is not accompanied by serious adverse events. Six months after switching to adalimumab, due to the «escape» of the effect of etanercept, the inflammatory changes in the patient were reversed; the volume of movements in the joints increased, and the laboratory parameters of the disease activity were normalized. After 1 year, there was a remission of the disease. The child managed to completely eliminate glucocorticosteroids for oral ingestion. The duration of the joint syndrome remission was 3 years. Adverse events were not serious and did not become a basis for drug withdrawal.","PeriodicalId":10919,"journal":{"name":"Current Paediatrics","volume":"84 1","pages":"314-320"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79113046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Self-plagiarism is one of the most controversial issues faced by participants in the publication process (authors, editors, reviewers). The article presents a brief analysis on the professional editorial communities' position on the problem. We give both comments and recommendations on formulation of the academic journal editorial policy. The paper provides the examples when the self-plagiarism is acceptable (minor copying of a few sentences, source fully and clearly referenced). In addition, it is pointed out that self-plagiarism can bear reputational and legal risks to an academic journal. Authors should consider this aspect when interacting with editors and reviewers.
{"title":"ЗАИМСТВОВАНИЯ СОБСТВЕННЫХ ТЕКСТОВ (САМОПЛАГИАТ) В РУКОПИСЯХ, ПРЕДСТАВЛЕННЫХ НА РАССМОТРЕНИЕ В НАУЧНЫЙ ЖУРНАЛ: РЕКОМЕНДАЦИИ ПО ФОРМУЛИРОВАНИЮ РЕДАКЦИОННОЙ ПОЛИТИКИ","authors":"Руслан Темирсултанович Сайгитов","doi":"10.15690/VSP.V16I4.1772","DOIUrl":"https://doi.org/10.15690/VSP.V16I4.1772","url":null,"abstract":"Self-plagiarism is one of the most controversial issues faced by participants in the publication process (authors, editors, reviewers). The article presents a brief analysis on the professional editorial communities' position on the problem. We give both comments and recommendations on formulation of the academic journal editorial policy. The paper provides the examples when the self-plagiarism is acceptable (minor copying of a few sentences, source fully and clearly referenced). In addition, it is pointed out that self-plagiarism can bear reputational and legal risks to an academic journal. Authors should consider this aspect when interacting with editors and reviewers.","PeriodicalId":10919,"journal":{"name":"Current Paediatrics","volume":"71 1","pages":"270-272"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88538292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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