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Sulcus-Deepening Trochleoplasty for High-Grade Trochlear Dysplasia: Demystifying the Procedure-a Review of the Current Literature. Sulcus加深Trochlear高级别发育不良的Trohlear切除术:揭开过程的神秘面纱——当前文献综述。
IF 4.1 2区 医学 Q1 Medicine Pub Date : 2023-11-01 Epub Date: 2023-09-12 DOI: 10.1007/s12178-023-09868-6
Magdalena Tarchala, Sarah Kerslake, Laurie A Hiemstra

Purpose of review: The most common and biomechanically influential pathoanatomic risk factor for recurrent patellofemoral instability is trochlear dysplasia. Sulcus-deepening trochleoplasty is a procedure developed to address high-grade trochlear dysplasia in the setting of patellofemoral instability. The purpose of this paper is to outline the current classification and surgical management of trochlear dysplasia as well as to review the current literature on the clinical outcomes and complications of sulcus-deepening trochleoplasty.

Recent findings: This review outlines the most recent literature reporting evidence behind the decision-making to perform a trochleoplasty in the setting of patellofemoral instability and high-grade trochlear dysplasia. Critical parameters include grade of trochlear dysplasia, severity of symptoms, pertinent physical examination findings, surgical techniques, modifications for skeletally immature patients, and considerations for the revision setting. Historic studies have elicited concerns regarding high reported complication rates for trochleoplasty; however, recent studies consistently report good clinical outcomes and acceptable complication rates, similar to those of other patellar stabilizing procedures. The addition of a trochleoplasty in patients with high-grade dysplasia results in a lower re-dislocation rate, significant improvements in patient-reported outcome measures (PROMs) as well as high levels of patient satisfaction and return to sport. The use of sulcus-deepening trochleoplasty for the treatment of high-grade dysplasia and recurrent patellofemoral instability is a well-established technique with good outcomes and an acceptable complication profile. In patients with high-grade dysplasia, trochleoplasty results in lower re-dislocation rates, high patient satisfaction scores, and good clinical and functional outcomes. An understanding of trochleoplasty and its indications should be in the armamentarium of surgeons treating patellofemoral instability.

综述目的:复发性髌股关节不稳定的最常见和生物力学影响的病理解剖危险因素是滑车发育不良。Sulcus加深滑车成形术是一种在髌股关节不稳定的情况下为解决高级别滑车发育不良而开发的手术。本文的目的是概述目前滑车发育不良的分类和手术治疗,并回顾目前关于沟加深滑车成形术的临床结果和并发症的文献。最近的发现:这篇综述概述了在髌股关节不稳定和高级别滑车发育不良的情况下决定进行滑车成形术背后的最新文献报告证据。关键参数包括滑车发育不良的分级、症状的严重程度、相关的体检结果、手术技术、骨骼发育不成熟患者的改良以及翻修设置的考虑因素。历史研究引起了人们对滑车成形术并发症发生率高的担忧;然而,最近的研究一致报告了良好的临床结果和可接受的并发症发生率,类似于其他髌骨稳定手术。在高度发育不良患者中增加滑车成形术可降低再脱位率,显著改善患者报告的预后指标(PROM),并提高患者满意度和重返运动。使用脑沟加深滑车成形术治疗高度发育不良和复发性髌股关节不稳定是一项公认的技术,具有良好的疗效和可接受的并发症。在高度发育不良患者中,滑车成形术可降低再脱位率,提高患者满意度,并取得良好的临床和功能结果。对滑车成形术及其适应症的理解应纳入治疗髌股关节不稳定的外科医生的装备中。
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引用次数: 0
Racial and Ethnic Disparities in the Management of Diabetic Feet. 糖尿病足治疗中的种族和民族差异。
IF 4.1 2区 医学 Q1 Medicine Pub Date : 2023-11-01 Epub Date: 2023-09-21 DOI: 10.1007/s12178-023-09867-7
Elizabeth O Clayton, Confidence Njoku-Austin, Devon M Scott, Jarrett D Cain, MaCalus V Hogan

Purpose of review: Diabetes mellitus is a chronic medical condition affecting many individuals worldwide and leads to billions of dollars spent within the healthcare system for its treatment and complications. Complications from diabetes include diabetic foot conditions that can have a devasting impact on quality of life. Diabetic foot ulcers and amputations occur in minority individuals at an increased rate compared to Caucasian individuals. This review provides an update examining the racial and ethnic disparities in the management of diabetic foot conditions and the differences in rates of amputation.

Recent findings: Current research continues to show a disparity as it relates to diabetic foot management. There are novel treatment options for diabetic foot ulcers that are currently being explored. However, there continues to be a lack in racial diversity in new treatment studies conducted in the USA. Individuals from racial and ethnic minority groups have diabetes at higher rates compared to Caucasian individuals, and are also more likely to develop diabetic foot ulcers and receive amputations. Over the last few years, more efforts have been made to improve health disparities. However, there needs to be an improvement in increasing racial diversity when investigating new therapies for diabetic foot ulcers.

综述目的:糖尿病是一种影响全球许多人的慢性疾病,导致医疗系统内花费数十亿美元用于治疗和并发症。糖尿病的并发症包括糖尿病足,这可能会对生活质量产生毁灭性影响。糖尿病足溃疡和截肢发生在少数民族人群中,与高加索人群相比,发生率增加。这篇综述提供了最新的研究糖尿病足疾病管理中的种族和民族差异以及截肢率的差异。最近的发现:目前的研究继续显示出与糖尿病足管理相关的差异。目前正在探索糖尿病足溃疡的新治疗方案。然而,在美国进行的新的治疗研究中,仍然缺乏种族多样性。与高加索人相比,来自种族和少数民族群体的人患糖尿病的比率更高,也更有可能患上糖尿病足溃疡并接受截肢手术。在过去几年中,为改善健康差距作出了更多努力。然而,在研究糖尿病足溃疡的新疗法时,需要在增加种族多样性方面有所改进。
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引用次数: 0
Turf Toe Injuries in the Athlete: an Updated Review of Treatment Options, Rehabilitation Protocols, and Return-to-Play Outcomes. 运动员草皮脚趾损伤:治疗方案、康复方案和重返赛场结果的最新综述。
IF 4.1 2区 医学 Q1 Medicine Pub Date : 2023-11-01 Epub Date: 2023-10-03 DOI: 10.1007/s12178-023-09870-y
Arjun Gupta, Priya K Singh, Amy L Xu, Rachel S Bronheim, Claire M McDaniel, Amiethab A Aiyer

Purpose of review: First metatarsophalangeal joint sprains or turf toe (TT) injuries occur secondary to forceful hyperextension of the great toe. TT injuries are common among athletes, especially those participating in football, soccer, basketball, dancing, and wrestling. This review summarizes the current treatment modalities, rehabilitation protocols, and return-to-play criteria, as well as performance outcomes of patients who have sustained TT injuries.

Recent findings: Less than 2% of TT injuries require surgery, but those that do are typically grade III injuries with damage to the MTP joint, evidence of bony injury, or severe instability. Rehabilitation protocols following non-operative management consist of 3 phases lasting up to 10 weeks, whereas protocols following operative management consist of 4 phases lasting up 20 weeks. Athletes with low-grade injuries typically achieve their prior level of performance. However, among athletes with higher grade injuries, treated both non-operatively and operatively, about 70% are expected to maintain their level of performance. The treatment protocol, return-to-play criteria, and overall performance outcomes for TT injuries depend on the severity and classification of the initial sprain. For grade I injuries, players may return to play once they experience minimal to no pain with normal weightbearing, traditionally after 3-5 days. For grade II injuries, or partial tears, players typically lose 2-4 weeks of play and may need additional support with taping when returning to play. For grade III injuries, or complete disruption of the plantar plate, athletes lose 4-6 weeks or more depending upon treatment strategy.

综述目的:第一跖趾关节扭伤或草皮趾(TT)损伤继发于大脚趾用力过伸。TT损伤在运动员中很常见,尤其是那些参加足球、足球、篮球、舞蹈和摔跤的运动员。这篇综述总结了目前的治疗模式、康复方案、重返赛场标准以及TT损伤患者的表现结果。最近的研究结果:不到2%的TT损伤需要手术,但需要手术的通常是III级损伤,伴有MTP关节损伤、骨损伤或严重不稳定。非手术治疗后的康复方案包括3个阶段,持续时间长达10周,而手术治疗后方案包括4个阶段,长达20周。轻度受伤的运动员通常能达到他们之前的水平。然而,在非手术和手术治疗的高级别损伤运动员中,预计约70%的人能保持他们的表现水平。TT损伤的治疗方案、重返赛场标准和整体表现结果取决于初始扭伤的严重程度和分类。对于一级损伤,球员在正常负重的情况下,通常在3-5天后,一旦疼痛最小或没有疼痛,就可以重返赛场。对于二级损伤或部分撕裂,球员通常会输掉2-4周的比赛,在重返赛场时可能需要额外的胶带支撑。对于III级损伤或足底板完全断裂,运动员会根据治疗策略损失4-6周或更长时间。
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引用次数: 0
Soft Tissue Lengthening for Flexion Dislocation of Patella. 软组织延长术治疗髌骨屈折脱位。
IF 4.1 2区 医学 Q1 Medicine Pub Date : 2023-11-01 Epub Date: 2023-09-04 DOI: 10.1007/s12178-023-09865-9
Clark Yin, Betina B Hinckel

Purpose of review: Obligatory dislocation of the patella (also known as habitual dislocation) is a rare subset of patellofemoral instability in which the patella dislocates every time the knee is flexed. The problem arises due to contracture of the quadriceps muscles. Soft tissue lengthening procedures such as quadriceps tendon lengthening are the mainstay of treatment, in contrast to medial patellofemoral reconstruction (MPFL-R) for the more common recurrent lateral patellar dislocation. The current review explores the existing literature surrounding the pathophysiology and treatment strategies for this unique cause of knee instability.

Recent findings: Flexion dislocation of the knee often presents in children when they begin to walk. It is also termed obligatory or habitual because the patella dislocates laterally with each flexion and extension cycle of the knee. In contrast to other forms of patellar dislocation, the displacement is painless in obligatory dislocation. Likewise, the underlying biomechanical cause of this issue is related to contracture of tissues lateral to the patella rather than disruption of medial soft tissues as seen in recurrent/traumatic dislocation or subluxation of the patella. A number of procedures have been described for management of obligatory dislocation of the patella, with the general consensus that a combination of procedures including release/lengthening of the proximal lateral soft tissues as a critical component for a successful outcome. Soft tissue release/lengthening has been performed for over 50 years to treat obligatory dislocation of the patella. This procedure must be used in combination with other proximal and distal reconstructive with careful intraoperative assessment of knee flexion and patellar tracking for satisfactory outcomes. Further research using standardized outcome measures is needed to identify the optimal step-wise approach in treatment of obligatory patellar dislocation.

综述目的:髌骨斜性脱位(也称为习惯性脱位)是髌股不稳定的一种罕见亚型,每次膝盖弯曲时髌骨都会脱位。这个问题是由于股四头肌挛缩引起的。软组织延长术,如股四头肌腱延长术是治疗的主要方法,而内侧髌股重建术(MPFL-R)治疗更常见的复发性外侧髌骨脱位。目前的综述探讨了现有的关于膝关节不稳定这一独特原因的病理生理学和治疗策略的文献。最近的研究结果:儿童在开始走路时经常出现膝关节屈曲脱位。它也被称为强制性的或习惯性的,因为髌骨在膝盖的每个屈曲和伸展周期都会发生侧向脱位。与其他形式的髌骨脱位相比,强制性脱位的移位是无痛的。同样,这个问题的潜在生物力学原因与髌骨外侧组织的挛缩有关,而不是髌骨复发/创伤性脱位或半脱位中内侧软组织的破坏。已经描述了许多治疗髌骨强制性脱位的手术,普遍认为,包括释放/延长近侧软组织在内的多种手术组合是成功治疗的关键组成部分。软组织松解/延长治疗髌骨强制性脱位已有50多年的历史。该手术必须与其他近端和远端重建结合使用,并在术中仔细评估膝关节屈曲和髌骨追踪,以获得满意的结果。需要使用标准化结果测量进行进一步研究,以确定治疗强制性髌骨脱位的最佳分步方法。
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引用次数: 0
Point-of-Care Ultrasound (POCUS) for Sideline Youth Sports Coverage. 护理点超声波(POCUS)用于边线青少年体育报道。
IF 4.1 2区 医学 Q1 Medicine Pub Date : 2023-11-01 Epub Date: 2023-08-11 DOI: 10.1007/s12178-023-09859-7
Jacob C Jones, Cassidy Schultz, Caroline Podvin, David Mikhail, Luke C Radel

Purpose of review: The purpose of this review is to discuss the use of point-of-care ultrasound for sideline youth sports coverage.

Recent findings: Participation in youth sports has been increasing, with trends that athletes are specializing earlier and competing at higher levels at younger ages (NSCH 2019, Fabricant 2013). Point-of-care ultrasound (POCUS) utilizes non-invasive imaging to diagnose and manage various musculoskeletal conditions ranging from traumatic injuries, such as fractures and intramuscular hematomas, to early screening for conditions such as asymptomatic knee lesions. Since it is well-tolerated by children and adolescents and allows for easy accessibility for sideline care, POCUS could provide a strong alternative to other imaging modalities such as x-ray and magnetic resonance imaging (MRI) as both have their limitations. Youth sideline sports coverage could be enhanced with immediate medical attention from ultrasound-trained medical professionals. On the sidelines of a traumatic injury, POCUS expedites patient care with immediate examination of acute injuries. In low resource and hard-to-reach locations such as a rural youth sporting event, it can be key in the triaging of injuries. As a supplement to a physical exam, the risk of a misdiagnosis is reduced, and a long, expensive trip to the hospital for unnecessary imaging studies may be avoided. Ultrasound is a versatile, non-invasive, radiation-free imaging modality that serves as an accessible option for sideline coverage at youth sporting events. Ultrasound is well-tolerated by children and adolescents. It can be used to evaluate, diagnose, and manage a range of musculoskeletal conditions at the sidelines of youth sports.

综述的目的:本综述的目的是讨论护理点超声在青少年副业体育报道中的应用。最近的研究结果:参与青少年体育运动的人数一直在增加,运动员的专业化程度更早,在更年轻的时候参加更高水平的比赛(NSCH 2019,Fabricant 2013)。护理点超声(POCUS)利用非侵入性成像来诊断和管理各种肌肉骨骼疾病,从创伤(如骨折和肌肉内血肿)到无症状膝盖损伤等疾病的早期筛查。由于儿童和青少年对POCUS的耐受性很好,并且可以方便地进行副业护理,因此POCUS可以为其他成像模式(如x射线和磁共振成像(MRI))提供强有力的替代方案,因为两者都有其局限性。受过超声波培训的医疗专业人员可以立即提供医疗服务,从而提高青少年副业运动的覆盖率。在创伤性损伤之外,POCUS通过立即检查急性损伤来加快患者护理。在资源匮乏、难以到达的地方,如农村青年体育赛事,这可能是对伤病进行分类的关键。作为体检的补充,可以降低误诊的风险,并可以避免去医院进行不必要的影像学研究的漫长而昂贵的旅行。超声波是一种多功能、无创、无辐射的成像方式,是青少年体育赛事场边报道的一种可供选择的方式。儿童和青少年对超声波的耐受性很好。它可以用于评估、诊断和管理青少年运动场外的一系列肌肉骨骼状况。
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引用次数: 0
Non-operative Management and Outcomes of Femoroacetabular Impingement Syndrome. 股骨髋臼撞击综合征的非手术治疗和结果。
IF 4.1 2区 医学 Q1 Medicine Pub Date : 2023-11-01 Epub Date: 2023-08-31 DOI: 10.1007/s12178-023-09863-x
Rosa M Pasculli, Elizabeth A Callahan, James Wu, Niam Edralin, William A Berrigan

Purpose: To serve as a guide for non-operative physicians in the management of femoroacetabular impingement syndrome and provide an algorithm as to when to refer patients for potential surgical management.

Recent findings: Supervised physical therapy programs that focus on active strengthening and core strengthening are more effective than unsupervised, passive, and non-core-focused programs. There is promising evidence for the use of intra-articular hyaluronic acid and PRP as adjunct treatment options. Recent systematic reviews and meta-analyses have found that in young active patients, hip arthroscopy demonstrates improved short-term outcomes over physical therapy. The decision for the management of FAIS is complex and should be specific to each patient. Consideration of the patient's age, timing to return to sport, longevity of treatment, hip morphology, and degree of cartilage degeneration is required to make an informed decision in the treatment of these patients.

目的:为非手术医生治疗股骨髋臼撞击综合征提供指导,并提供何时转诊患者进行潜在手术治疗的算法。最近的发现:专注于主动强化和核心强化的有监督的物理治疗项目比无监督、被动和非核心强化的项目更有效。有很好的证据表明关节内透明质酸和PRP作为辅助治疗选择。最近的系统综述和荟萃分析发现,在年轻活跃的患者中,髋关节镜检查显示出比物理治疗改善了短期疗效。FAIS的管理决策是复杂的,应该针对每个患者。在治疗这些患者时,需要考虑患者的年龄、恢复运动的时间、治疗寿命、髋关节形态和软骨退化程度,以做出明智的决定。
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引用次数: 0
The Role of Inclusion in Increasing Diversity and Retention Across Surgical Residencies: a Literature Review. 包容性在提高外科住院医师多样性和保留率中的作用:文献综述。
IF 4.1 2区 医学 Q1 Medicine Pub Date : 2023-11-01 Epub Date: 2023-09-16 DOI: 10.1007/s12178-023-09866-8
Ucheze C Ononuju, Jakara B Morgan, Gabriella E Ode

Purpose of review: Across surgical specialties, residencies are incentivized to improve program diversity, most often through recruitment of underrepresented minority (URM), women, LGBTQ, and disabled applicants. However, residency attrition remains high in these groups, highlighting the need for specific inclusion initiatives to improve retention and support for these cohorts. A better understanding of previous efforts at retention is paramount. This paper reviews the existing literature on inclusion and retention efforts in surgical residencies.

Recent findings: A literature search was conducted using PubMed Central. Published articles were filtered based on date (2018-2023) and relevancy. Articles were evaluated holistically and focused on methods in increasing diversity and inclusion in residency retention. Through formal literature review focusing on pertinent research topic terms (i.e., inclusion, diversity, residency, surgery, retention), efforts that included inclusion initiatives, improving residency retention, and diversifying leadership were overarching themes. In recent years, there have been marked strides and improvements in encouraging resident diversity and inclusion. However, more widespread efforts with proven efficacy are needed in order to improve residency retention and to increase and maintain diversity in leadership in surgery.

审查目的:在整个外科专业中,住院医师都受到激励,以提高项目的多样性,通常是通过招募代表性不足的少数族裔(URM)、女性、LGBTQ和残疾申请人。然而,这些群体的居住人员流失率仍然很高,这突出表明需要采取具体的包容性举措来提高对这些群体的保留和支持。更好地了解以前在留住人才方面所做的努力至关重要。本文综述了外科住院患者的纳入和保留工作的现有文献。最近的发现:使用PubMed Central进行文献检索。已发表的文章根据日期(2018-2023)和相关性进行过滤。对文章进行了全面评估,重点讨论了增加居留权保留的多样性和包容性的方法。通过专注于相关研究主题术语(即包容性、多样性、住院医师、手术、保留)的正式文献综述,包括包容性举措、提高住院医师保留率和多样化领导力在内的努力是首要主题。近年来,在鼓励居民多样性和包容性方面取得了显著进展和改进。然而,为了提高住院医师的保留率,增加和保持外科领导层的多样性,还需要更广泛的、已证明有效的努力。
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引用次数: 0
Pediatric Heterotopic Ossification: A Comprehensive Review. 小儿异位骨化症:综述。
IF 4.1 2区 医学 Q1 Medicine Pub Date : 2023-11-01 Epub Date: 2023-08-17 DOI: 10.1007/s12178-023-09862-y
Alexander R Markes, Nikit Venishetty, Andrew Gatto, Ishaan Swarup

Purpose of review: The purpose of this review is to provide a comprehensive analysis of heterotopic ossification (HO) in pediatric patients, including an in-depth examination of the risk factors associated with this condition, current prophylactic measures, and available management strategies.

Recent findings: HO is a medical disorder in which bone tissue inexplicably develops in soft tissues such as muscles and tendons. It involves the formation of mature, lamellar bone in extra-skeletal soft tissue, and its formation is influenced by oxygen tension, pH, the availability of micronutrients, and mechanical stimulation. HO has many cellular origins, with the most common theory being multipotent cells in local tissue. The diagnosis of HO is typically made based on exam, radiographs, and CT. Management includes both prophylactic nonsurgical options and surgical resection for severe or recalcitrant cases. The review highlights the incidence, risk factors, and management strategies associated with HO in pediatric patients. HO is a rare condition in children, with severe neurologic injury being the most common cause. Pediatric patients most commonly develop HO following severe neurologic injury, followed by trauma and surgery. Current prophylactic measures, include nonsteroidal anti-inflammatory drugs and radiation therapy though limited literature on their use in the pediatric population exists. For recalcitrant symptomatic cases, wide surgical resection can be considered but has a higher risk profile and associated morbidity. This review highlights the need for further pediatric specific research to inform guidelines and management strategies for this debilitating condition.

综述的目的:本综述的目的是对儿科患者的异位骨化(HO)进行全面分析,包括深入检查与这种情况相关的风险因素、当前的预防措施和可用的管理策略。最近的发现:HO是一种医学疾病,骨组织莫名其妙地在肌肉和肌腱等软组织中发育。它涉及在骨骼外软组织中形成成熟的板层骨,其形成受到氧张力、pH、微量营养素的可用性和机械刺激的影响。HO有许多细胞起源,最常见的理论是局部组织中的多能细胞。HO的诊断通常基于检查、X线片和CT。治疗包括预防性非手术选择和严重或顽固病例的手术切除。该综述强调了儿科患者HO的发病率、危险因素和管理策略。HO是一种罕见的儿童疾病,最常见的原因是严重的神经损伤。儿科患者最常见的是在严重的神经损伤后发生HO,其次是创伤和手术。目前的预防措施包括非甾体抗炎药和放射治疗,尽管关于它们在儿科人群中的使用的文献有限。对于顽固性症状病例,可以考虑进行广泛的手术切除,但风险较高,发病率较高。这篇综述强调了进一步的儿科特定研究的必要性,为这种衰弱性疾病的指导方针和管理策略提供信息。
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引用次数: 0
Scheuermann Kyphosis: Current Concepts and Management. Scheuermann Kyphosis:当前概念和管理。
IF 4.1 2区 医学 Q1 Medicine Pub Date : 2023-11-01 Epub Date: 2023-08-24 DOI: 10.1007/s12178-023-09861-z
Jennifer M O'Donnell, Wei Wu, Alex Youn, Angad Mann, Ishaan Swarup

Purpose of review: Scheuermann's kyphosis (SK) is a developmental deformity of the spine that affects up to 8% of children in the US. Although, the natural progression of SK is noted to be gradual over years, severe deformity can be associated with significant morbidity. Thorough clinical examination and interpretation of relevant imaging help differentiate and confirm this diagnosis. Treatment includes both operative and nonoperative approaches. The purpose of this article is to provide an updated overview of the current theories of its pathogenesis, as well as the principles of diagnosis and treatment of SK.

Recent findings: Although a definitive, unified theory continues to be elusive, numerous reports in the past decade provide insight into the pathophysiology of SK. These include alterations in mechanical stress and/or hormonal disturbances. Candidate genes have also been identified to be linked to the inheritance of SK. Updates to nonoperative treatment include the effectiveness of dedicated exercise programs, as well as the types and duration of orthotic treatment. Advances in surgical technique can be observed with a trend toward a posterior-only approach, with supporting evidence for careful evaluation of both the sagittal and coronal planes to determine fusion levels in order to avoid postoperative junctional pathologies. SK is an important cause of structural or rigid kyphosis. It can lead to significant morbidity in severe cases. Treatment is based on curve magnitude and symptoms. Nonoperative treatment consists of physical therapy in symptomatic patients, and bracing can be added for skeletally mature patients. Operative management can be considered in patients with large, progressive, and symptomatic deformity. Future studies can benefit from a focused investigation into patient-reported outcomes after undergoing appropriate treatment.

综述目的:Scheuermann后凸畸形(SK)是一种脊柱发育畸形,在美国影响多达8%的儿童。尽管SK的自然进展是多年来逐渐的,但严重畸形可能会导致显著的发病率。全面的临床检查和相关影像学的解释有助于鉴别和确认这一诊断。治疗包括手术和非手术两种方法。这篇文章的目的是提供对其发病机制的当前理论以及SK的诊断和治疗原则的最新概述。最近的发现:尽管一个明确的、统一的理论仍然难以捉摸,但在过去十年中的许多报道提供了对SK病理生理学的深入了解。其中包括机械应激和/或激素紊乱的改变。候选基因也被确定与SK的遗传有关。非手术治疗的更新包括专门锻炼计划的有效性,以及矫正治疗的类型和持续时间。可以观察到外科技术的进步,只采用后部入路,有支持性证据可以仔细评估矢状面和冠状面,以确定融合水平,从而避免术后交界病变。SK是结构性或刚性后凸的重要原因。在严重的情况下,它会导致显著的发病率。治疗是基于曲线幅度和症状。非手术治疗包括对有症状的患者进行物理治疗,对骨骼成熟的患者可以增加支架。对于有较大、进行性和症状性畸形的患者,可以考虑手术治疗。未来的研究可以受益于对患者在接受适当治疗后报告的结果进行重点调查。
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引用次数: 0
Update on the Diagnosis and Management of Early-onset Scoliosis. 早期起病性脊柱侧弯的诊断和治疗进展。
IF 4.1 2区 医学 Q1 Medicine Pub Date : 2023-10-01 Epub Date: 2023-08-24 DOI: 10.1007/s12178-023-09848-w
Leta Ashebo, Jason B Anari, Patrick J Cahill

Purpose of review: In this article, we review the most recent advancements in the approaches to EOS diagnosis and assessment, surgical indications and options, and basic science innovation in the space of early-onset scoliosis research.

Recent findings: Early-onset scoliosis (EOS) covers a diverse, heterogeneous range of spinal and chest wall deformities that affect children under 10 years old. Recent efforts have sought to examine the validity and reliability of a recently developed classification system to better standardize the presentation of EOS. There has also been focused attention on developing safer, informative, and readily available imaging and clinical assessment tools, from reduced micro-dose radiographs, quantitative dynamic MRIs, and pulmonary function tests. Basic science innovation in EOS has centered on developing large animal models capable of replicating scoliotic deformity to better evaluate corrective technologies. And given the increased variety in approaches to managing EOS in recent years, there exist few clear guidelines around surgical indications across EOS etiologies. Despite this, over the past two decades, there has been a considerable shift in the spinal implant landscape toward growth-friendly instrumentation, particularly the utilization of MCGR implants. With the advent of new biological and basic science treatments and therapies extending survivorship for disease etiologies associated with EOS, the treatment for EOS has steadily evolved in recent years. With this has come a rising volume and variation in management options for EOS, as well as the need for multidisciplinary and creative approaches to treating patients with these complex and heterogeneous disorders.

综述目的:在这篇文章中,我们回顾了EOS诊断和评估方法、手术指征和选择以及早发性脊柱侧弯研究领域的基础科学创新的最新进展。最近的研究结果:早发性脊柱侧弯(EOS)涵盖了影响10岁以下儿童的各种各样的脊柱和胸壁畸形。最近的努力试图检验最近开发的分类系统的有效性和可靠性,以更好地标准化EOS的表示。人们还将注意力集中在开发更安全、信息丰富、易于获得的成像和临床评估工具上,包括减少微剂量射线照相、定量动态核磁共振成像和肺功能测试。EOS的基础科学创新集中在开发能够复制脊柱侧弯畸形的大型动物模型,以更好地评估矫正技术。鉴于近年来治疗EOS的方法越来越多,关于EOS病因的手术适应症,几乎没有明确的指南。尽管如此,在过去的二十年里,脊柱植入物领域已经发生了相当大的转变,向生长友好型器械发展,特别是MCGR植入物的使用。随着新的生物学和基础科学治疗方法的出现,以及延长EOS相关病因存活率的疗法,近年来EOS的治疗方法稳步发展。随之而来的是EOS管理选择的数量和变化不断增加,以及需要多学科和创造性的方法来治疗这些复杂和异质性疾病的患者。
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Current Reviews in Musculoskeletal Medicine
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