Cutis最新文献

Although dermatology relies primarily on sight and touch, clinicians often overlook smell despite encountering diagnostic odors. We reviewed PubMed and Google Scholar for articles on disease-related cutaneous odors. Bacterial and fungal infections emit characteristic malodors, while genetic and metabolic disorders (eg, Darier disease, trimethylaminuria, phenylketonuria, maple syrup urine disease) and organ dysfunction (renal and hepatic failure) produce unique scents. Preliminary evidence also suggests melanoma may have a distinct odor detectable by canines. Although objective odor measurement remains challenging, incorporating olfaction could enhance diagnosis and merits further research.

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) require prompt hospital admission with access to inpatient dermatologic care. Delayed admission of 5 days or more has been associated with increases in overall mortality, bacteremia, intensive care unit (ICU) admission, and length of stay. In this study, we analyzed the association between admission pathway and clinical outcomes of patients with SJS/TEN. A single-center retrospective chart review was performed at Atrium Health Wake Forest Baptist Medical Center (AHWFBMC)(Winston-Salem, North Carolina), to assess demographics, comorbidities, outside hospital transfer status, complications during admission, inpatient length of stay in days, interventions received, and site of admission: directly from AHWFBMC emergency department or transferred from an outside hospital.

Cosmetic laser and energy-based body-contouring procedures are increasingly sought by individuals with skin of color (SOC). This review outlines current evidence and clinical experience surrounding laser treatments for dermatosis papulosa nigra, acne scars, photoaging, and hyperpigmentation, as well as nonsurgical fat-reduction techniques. Nonablative fractional (NAF) lasers and 1064-nm Nd:YAG devices demonstrate favorable safety profiles in SOC when appropriately applied. Postprocedural photoprotection and the use of topical melanogenesis inhibitors are key to minimizing pigmentary complications. Although early data support the use of ultrasound, radiofrequency, and magnetic-based contouring in SOC, more robust studies are needed. This review aims to guide clinicians in optimizing outcomes and minimizing risks for patients with darker skin types undergoing cosmetic procedures.

While strong relationships with mentors and advisers are critical to navigating the dermatology match process, the advice around the match process that medical students receive from different individuals can be contradictory. In this study, we sought to examine the advice that mentors provide to medical students applying to dermatology residency programs via a 14-question anonymous survey covering topics such as research years, away rotations, dual applying, couples matching, program signaling, PGY-1 year, geographic signaling, interviewing, and volunteering in medical school.

Spironolactone is an effective systemic treatment for acne in women and likely is an underutilized alternative to oral antibiotics. It is used off label for all types of acne and has shown effectiveness for both facial and truncal acne. We recommend a starting dose of 100 mg/d, as most patients can tolerate it and it has superior effectiveness to lower doses. The most common adverse effects of spironolactone are lightheadedness; headache; and menstrual irregularities, which tend to be dose dependent and can be prevented or treated using combined oral contraceptives. Potassium monitoring is of low usefulness in young healthy women, and studies have not identified an association between spironolactone use and increased risk for cancer. This article provides an overview of spironolactone for the treatment of acne, including recent clinical trials and practical strategies for patient selection, dosing, adverse effect management, and monitoring.