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A content-aware chatbot based on GPT 4 provides trustworthy recommendations for Cone-Beam CT guidelines in dental imaging. 基于 GPT 4 的内容感知聊天机器人为牙科成像中的锥形束计算机断层扫描指南提供值得信赖的建议。
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-02-08 DOI: 10.1093/dmfr/twad015
Maximilian Frederik Russe, Alexander Rau, Michael Andreas Ermer, René Rothweiler, Sina Wenger, Klara Klöble, Ralf K W Schulze, Fabian Bamberg, Rainer Schmelzeisen, Marco Reisert, Wiebke Semper-Hogg

Objectives: To develop a content-aware chatbot based on GPT-3.5-Turbo and GPT-4 with specialized knowledge on the German S2 Cone-Beam CT (CBCT) dental imaging guideline and to compare the performance against humans.

Methods: The LlamaIndex software library was used to integrate the guideline context into the chatbots. Based on the CBCT S2 guideline, 40 questions were posed to content-aware chatbots and early career and senior practitioners with different levels of experience served as reference. The chatbots' performance was compared in terms of recommendation accuracy and explanation quality. Chi-square test and one-tailed Wilcoxon signed rank test evaluated accuracy and explanation quality, respectively.

Results: The GPT-4 based chatbot provided 100% correct recommendations and superior explanation quality compared to the one based on GPT3.5-Turbo (87.5% vs. 57.5% for GPT-3.5-Turbo; P = .003). Moreover, it outperformed early career practitioners in correct answers (P = .002 and P = .032) and earned higher trust than the chatbot using GPT-3.5-Turbo (P = 0.006).

Conclusions: A content-aware chatbot using GPT-4 reliably provided recommendations according to current consensus guidelines. The responses were deemed trustworthy and transparent, and therefore facilitate the integration of artificial intelligence into clinical decision-making.

目的开发基于 GPT-3.5-Turbo 和 GPT-4 的内容感知聊天机器人,该聊天机器人具备德国 S2 锥束 CT(CBCT)牙科成像指南的专业知识,并将其性能与人类进行比较:方法:使用 LlamaIndex 软件库将指南内容整合到聊天机器人中。根据 CBCT S2 指南,向内容感知聊天机器人提出了 40 个问题,并以不同经验水平的早期和资深从业者作为参考。聊天机器人在推荐准确性和解释质量方面的表现进行了比较。对准确性和解释质量分别进行了卡方检验和单尾 Wilcoxon 符号秩检验:结果:与基于 GPT3.5-Turbo 的聊天机器人相比,基于 GPT-4 的聊天机器人提供了 100% 的正确推荐和更高的解释质量(87.5% vs. 57.5% for GPT-3.5-Turbo;p = 0.003)。此外,与使用 GPT-3.5-Turbo 的聊天机器人相比,GPT-3.5-Turbo 的正确答案率(p = 0.002 和 p = 0.032)和信任度(p = 0.006)均优于早期职业从业者:使用 GPT-4 的内容感知聊天机器人根据当前的共识指南提供了可靠的建议。结论:使用 GPT-4 的内容感知聊天机器人根据当前的共识指南提供了可靠的建议,其回复被认为是可信和透明的,因此促进了人工智能与临床决策的整合。
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引用次数: 0
Mask refinement network for tooth segmentation on panoramic radiographs. 用于全景 X 光片上牙齿分割的掩模细化网络。
IF 3.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-02-08 DOI: 10.1093/dmfr/twad012
Li Niu, Shengwei Zhong, Zhiyu Yang, Baochun Tan, Junjie Zhao, Wei Zhou, Peng Zhang, Lingchen Hua, Weibin Sun, Houxuan Li

Objectives: Instance-level tooth segmentation extracts abundant localization and shape information from panoramic radiographs (PRs). The aim of this study was to evaluate the performance of a mask refinement network that extracts precise tooth edges.

Methods: A public dataset which consists of 543 PRs and 16211 labelled teeth was utilized. The structure of a typical Mask Region-based Convolutional Neural Network (Mask RCNN) was used as the baseline. A novel loss function was designed focus on producing accurate mask edges. In addition to our proposed method, 3 existing tooth segmentation methods were also implemented on the dataset for comparative analysis. The average precisions (APs), mean intersection over union (mIoU), and mean Hausdorff distance (mHAU) were exploited to evaluate the performance of the network.

Results: A novel mask refinement region-based convolutional neural network was designed based on Mask RCNN architecture to extract refined masks for individual tooth on PRs. A total of 3311 teeth were correctly detected from 3382 tested teeth in 111 PRs. The AP, precision, and recall were 0.686, 0.979, and 0.952, respectively. Moreover, the mIoU and mHAU achieved 0.941 and 9.7, respectively, which are significantly better than the other existing segmentation methods.

Conclusions: This study proposed an efficient deep learning algorithm for accurately extracting the mask of any individual tooth from PRs. Precise tooth masks can provide valuable reference for clinical diagnosis and treatment. This algorithm is a fundamental basis for further automated processing applications.

目标实例级牙齿分割可从全景放射照片(PR)中提取丰富的定位和形状信息。本研究旨在评估可精确提取牙齿边缘的掩膜细化网络的性能:研究利用了一个公共数据集,该数据集由 543 个全景X光片和 16211 个标记牙齿组成。以典型的基于掩膜区域的卷积神经网络(Mask RCNN)结构为基准。我们设计了一个新颖的损失函数,重点是生成准确的掩膜边缘。除了我们提出的方法外,还在数据集上实施了 3 种现有的牙齿分割方法,以进行比较分析。利用平均精确度(APs)、平均交集大于联合(mIoU)和平均豪斯多夫距离(mHAU)来评估网络的性能:基于掩模 RCNN 架构设计了一种新颖的基于掩模细化区域的卷积神经网络,用于提取 PR 上单个牙齿的细化掩模。从 111 份公共关系中的 3382 颗被测牙齿中,共正确检测出 3311 颗牙齿。AP、精确度和召回率分别为 0.686、0.979 和 0.952。此外,mIoU 和 mHAU 分别达到了 0.941 和 9.7,明显优于其他现有的分割方法:本研究提出了一种高效的深度学习算法,用于从PR中精确提取任何单个牙齿的掩膜。精确的牙齿掩模可为临床诊断和治疗提供有价值的参考。该算法是进一步自动化处理应用的基础。
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引用次数: 0
High-density objects in exomass affect the volume of high-density objects inside the field of view. 外质中的高密度物体会影响视场内高密度物体的体积。
IF 3.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-02-08 DOI: 10.1093/dmfr/twad014
Fernanda Coelho-Silva, Deivi Cascante-Sequeira, Marcela Tarosso Réa, Matheus L Oliveira, Deborah Queiroz Freitas, Francisco Haiter-Neto, Sergio Lins de-Azevedo-Vaz

Objectives: To evaluate the effect of the presence and the number of high-density objects in the exomass on the volume of a high-density object in cone-beam CT (CBCT).

Methods: Cylinders of cobalt-chromium (Co-Cr), titanium (Ti), and zirconium (Zi) were inserted into a polymethylmethacrylate phantom in five different combinations of number and position: 1-no cylinder; 2-one cylinder in a posterior region; 3-one cylinder in an anterior region; 4-two cylinders in posterior regions; and 5-three cylinders in anterior and posterior regions. The phantom underwent CBCT scanning using OP300 and X800 systems, with the afore mentioned cylinders of the same composition placed in the exomass and an additional high-density cylinder placed in the centre of the field of view (FOV), corresponding to the left-anterior region. The tomographic volume of the cylinder inside the FOV was measured using semi-automatic segmentation. The volumetric alteration (VA) between the segmented and physical volumes, in percentage, was compared among the experimental groups using repeated measures ANOVA and Tukey post-hoc (α = 5%).

Results: The factors material, combination, and their interaction affected the volume or both CBCT systems. In OP300, more cylinders in the exomass reduced the VA, mainly for Co-Cr. In X800, more cylinders in the exomass tended to increase the VA inside the FOV, except for Zi.

Conclusions: In general, the presence of high-density objects in the exomass influences the VA of the object inside the FOV, although this oscillates according to object composition, number and position in the exomass, and CBCT system.

目的:评估外质中高密度物体的存在和数量对锥形束 CT 中高密度物体体积的影响:评估外质中高密度物体的存在和数量对锥束 CT(CBCT)中高密度物体体积的影响:将钴铬(Co-Cr)、钛(Ti)和锆(Zi)圆柱体以五种不同的数量和位置组合插入聚甲基丙烯酸甲酯模型中:1 无圆柱体;2 在后部区域插入一个圆柱体;3 在前部区域插入一个圆柱体;4 在后部区域插入两个圆柱体;5 在前部和后部区域插入三个圆柱体。使用 OP300 和 X800 系统对模型进行 CBCT 扫描,将上述相同成分的圆柱体放置在体外,并在视野(FOV)中心放置一个额外的高密度圆柱体,相当于左前方区域。采用半自动分割法测量 FOV 内圆柱体的断层体积。使用重复测量方差分析和 Tukey 事后分析(α = 5%)比较了各实验组之间分割体积和实际体积的体积变化(VA)(百分比):结果:材料、组合及其交互作用等因素对两种 CBCT 系统的体积都有影响。在 OP300 中,外质中的圆柱体越多,VA 越小,主要是钴铬合金。在 X800 中,除 Zi 外,更多的圆柱体往往会增加 FOV 内的 VA:总的来说,外积物中高密度物体的存在会影响 FOV 内物体的 VA,尽管这会随着物体的组成、外积物的数量和位置以及 CBCT 系统的不同而摆动。
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引用次数: 0
Determination of masseter and temporal muscle thickness by ultrasound and muscle hardness by shear wave elastography in healthy adults as reference values. 用超声波测定健康成年人的颌下肌和颞肌厚度,并用剪切波弹性成像法测定肌肉硬度作为参考值。
IF 3.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-02-08 DOI: 10.1093/dmfr/twad013
Ayşe Nur Koruyucu, Firdevs Aşantoğrol

Objectives: The purpose of this study is to prospectively investigate the reference values of masseter and temporal muscle thicknesses by ultrasonography and muscle hardness values by shear wave elastography in healthy adults.

Methods: The sample of the study consisted of a total of 160 healthy individuals aged between 18 and 59, including 80 women and 80 men. By examining the right and left sides of each participant, thickness and hardness values were obtained for 320 masseter muscles and 320 temporal muscles in total.

Results: The mean masseter muscle thickness was found to be 1.09 cm at rest and 1.40 cm in contraction. The mean temporal muscle thickness was found to be 0.88 cm at rest and 0.98 cm in contraction. The thickness values of the masseter and temporal muscles were significantly greater in the male participants than in the female participants (P < .001). While there were significant differences between the right and left masseter muscle thickness values at rest and in contraction, the values of the temporal muscles did not show a significant difference between the sides. While the resting hardness (rSWE) of the masseter muscle was transversally 6.91 kPa and longitudinally 8.49 kPa, these values in contraction (cSWE) were found, respectively, 31.40 and 35.65 kPa. The median temporal muscle hardness values were 8.84 kPa at rest and 20.43 kPa in contraction. Masseter and temporal muscle hardness values at rest and in contraction were significantly higher among the male participants compared to the female participants (P < .001).

Conclusion: In this study, reference values for the thickness and hardness of the masseter and temporal muscles are reported. Knowing these values will make it easier to assess pain in the masseter and temporal muscles and determine the diagnosis and prognosis of masticatory muscle pathologies by allowing the morphological and functional assessments of these muscles, and it will identify ranges for reference parameters.

研究目的本研究的目的是通过超声波检查和剪切波弹性检查,前瞻性地调查健康成年人颌面部和颞部肌肉厚度的参考值和肌肉硬度值:研究样本由 160 名年龄在 18 至 59 岁之间的健康人组成,其中包括 80 名女性和 80 名男性。通过检查每位受试者的左右两侧肌肉,共获得了 320 块颌面肌和 320 块颞肌的厚度和硬度值:结果:发现静止时的平均颌下肌厚度为 1.09 厘米,收缩时为 1.40 厘米。静止时颞肌的平均厚度为 0.88 厘米,收缩时为 0.98 厘米。男性受试者的颌下肌和颞肌厚度值明显高于女性受试者(P本研究报告了颌下肌和颞肌厚度和硬度的参考值。通过对这些肌肉进行形态和功能评估,了解这些值将更容易评估咀嚼肌和颞肌的疼痛,确定咀嚼肌病变的诊断和预后,并确定参考参数的范围。
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引用次数: 0
Landmark annotation through feature combinations: a comparative study on cephalometric images with in-depth analysis of model's explainability. 通过特征组合进行地标标注:对头颅测量图像进行比较研究,并深入分析模型的可解释性。
IF 3.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-02-08 DOI: 10.1093/dmfr/twad011
Rashmi S, Srinath S, Prashanth S Murthy, Seema Deshmukh

Objectives: The objectives of this study are to explore and evaluate the automation of anatomical landmark localization in cephalometric images using machine learning techniques, with a focus on feature extraction and combinations, contextual analysis, and model interpretability through Shapley Additive exPlanations (SHAP) values.

Methods: We conducted extensive experimentation on a private dataset of 300 lateral cephalograms to thoroughly study the annotation results obtained using pixel feature descriptors including raw pixel, gradient magnitude, gradient direction, and histogram-oriented gradient (HOG) values. The study includes evaluation and comparison of these feature descriptions calculated at different contexts namely local, pyramid, and global. The feature descriptor obtained using individual combinations is used to discern between landmark and nonlandmark pixels using classification method. Additionally, this study addresses the opacity of LGBM ensemble tree models across landmarks, introducing SHAP values to enhance interpretability.

Results: The performance of feature combinations was assessed using metrics like mean radial error, standard deviation, success detection rate (SDR) (2 mm), and test time. Remarkably, among all the combinations explored, both the HOG and gradient direction operations demonstrated significant performance across all context combinations. At the contextual level, the global texture outperformed the others, although it came with the trade-off of increased test time. The HOG in the local context emerged as the top performer with an SDR of 75.84% compared to others.

Conclusions: The presented analysis enhances the understanding of the significance of different features and their combinations in the realm of landmark annotation but also paves the way for further exploration of landmark-specific feature combination methods, facilitated by explainability.

研究目的本研究的目的是利用机器学习技术探索和评估头颅测量图像中解剖地标定位的自动化,重点是特征提取和组合、上下文分析以及通过夏普利加法平面(SHAP)值实现的模型可解释性:我们在一个包含 300 张侧头颅照片的私人数据集上进行了大量实验,深入研究了使用像素特征描述器(包括原始像素、梯度大小、梯度方向和直方图导向梯度(HOG)值)获得的注释结果。研究包括评估和比较在不同情况下(即局部、金字塔和全局)计算的这些特征描述。使用单个组合获得的特征描述符可通过分类方法区分地标和非地标像素。此外,本研究还解决了 LGBM 组合树模型在地标间的不透明性问题,引入了 SHAP 值以增强可解释性:使用平均径向误差、标准偏差、成功检测率 (SDR) (2 mm) 和测试时间等指标评估了特征组合的性能。值得注意的是,在所有探索的组合中,HOG 和梯度方向操作在所有上下文组合中都表现出了显著的性能。在上下文层面上,全局纹理的性能优于其他纹理,但同时也增加了测试时间。局部上下文中的 HOG 以 75.84% 的 SDR 与其他操作相比表现最佳:本文的分析加深了人们对不同特征及其组合在地标注释领域的重要性的理解,同时也为进一步探索地标特定特征组合方法铺平了道路,可解释性也为进一步探索地标特定特征组合方法提供了便利。
{"title":"Landmark annotation through feature combinations: a comparative study on cephalometric images with in-depth analysis of model's explainability.","authors":"Rashmi S, Srinath S, Prashanth S Murthy, Seema Deshmukh","doi":"10.1093/dmfr/twad011","DOIUrl":"10.1093/dmfr/twad011","url":null,"abstract":"<p><strong>Objectives: </strong>The objectives of this study are to explore and evaluate the automation of anatomical landmark localization in cephalometric images using machine learning techniques, with a focus on feature extraction and combinations, contextual analysis, and model interpretability through Shapley Additive exPlanations (SHAP) values.</p><p><strong>Methods: </strong>We conducted extensive experimentation on a private dataset of 300 lateral cephalograms to thoroughly study the annotation results obtained using pixel feature descriptors including raw pixel, gradient magnitude, gradient direction, and histogram-oriented gradient (HOG) values. The study includes evaluation and comparison of these feature descriptions calculated at different contexts namely local, pyramid, and global. The feature descriptor obtained using individual combinations is used to discern between landmark and nonlandmark pixels using classification method. Additionally, this study addresses the opacity of LGBM ensemble tree models across landmarks, introducing SHAP values to enhance interpretability.</p><p><strong>Results: </strong>The performance of feature combinations was assessed using metrics like mean radial error, standard deviation, success detection rate (SDR) (2 mm), and test time. Remarkably, among all the combinations explored, both the HOG and gradient direction operations demonstrated significant performance across all context combinations. At the contextual level, the global texture outperformed the others, although it came with the trade-off of increased test time. The HOG in the local context emerged as the top performer with an SDR of 75.84% compared to others.</p><p><strong>Conclusions: </strong>The presented analysis enhances the understanding of the significance of different features and their combinations in the realm of landmark annotation but also paves the way for further exploration of landmark-specific feature combination methods, facilitated by explainability.</p>","PeriodicalId":11261,"journal":{"name":"Dento maxillo facial radiology","volume":" ","pages":"115-126"},"PeriodicalIF":3.3,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139080441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultra-low-dose photon-counting CT of paranasal sinus: an in vivo comparison of radiation dose and image quality to cone-beam CT. 鼻旁窦超低剂量光子计数 CT:与锥形束 CT 的辐射剂量和图像质量的活体比较。
IF 3.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-02-08 DOI: 10.1093/dmfr/twad010
Hanns Leonhard Kaatsch, Florian Fulisch, Daniel Dillinger, Laura Kubitscheck, Benjamin V Becker, Joel Piechotka, Marc A Brockmann, Matthias F Froelich, Stefan O Schoenberg, Daniel Overhoff, Stephan Waldeck

Purpose: This study investigated the differences in subjective and objective image parameters as well as dose exposure of photon-counting CT (PCCT) compared to cone-beam CT (CBCT) in paranasal sinus imaging for the assessment of rhinosinusitis and sinonasal anatomy.

Methods: This single-centre retrospective study included 100 patients, who underwent either clinically indicated PCCT or CBCT of the paranasal sinus. Two blinded experienced ENT radiologists graded image quality and delineation of specific anatomical structures on a 5-point Likert scale. In addition, contrast-to-noise ratio (CNR) and applied radiation doses were compared among both techniques.

Results: Image quality and delineation of bone structures in paranasal sinus PCCT was subjectively rated superior by both readers compared to CBCT (P < .001). CNR was significantly higher for photon-counting CT (P < .001). Mean effective dose for PCCT examinations was significantly lower than for CBCT (0.038 mSv ± 0.009 vs. 0.14 mSv ± 0.011; P < .001).

Conclusion: In a performance comparison of PCCT and a modern CBCT scanner in paranasal sinus imaging, we demonstrated that first-use PCCT in clinical routine provides higher subjective image quality accompanied by higher CNR at close to a quarter of the dose exposure compared to CBCT.

目的:本研究调查了光子计数 CT(PCCT)与锥束 CT(CBCT)在鼻窦旁成像评估鼻炎和鼻窦解剖方面的主观和客观图像参数以及剂量暴露的差异:这项单中心回顾性研究包括 100 名患者,他们都接受了有临床指征的 PCCT 或 CBCT 副鼻窦成像。两名经验丰富的耳鼻喉科放射科盲人医生以 5 点李克特量表对图像质量和特定解剖结构的清晰度进行评分。此外,还比较了两种技术的对比噪声比(CNR)和应用辐射剂量:结果:与 CBCT 相比,两位读者对鼻旁窦 PCCT 的图像质量和骨结构轮廓的主观评价都更高:通过比较 PCCT 和现代 CBCT 扫描仪在鼻旁窦成像中的性能,我们证明在临床常规中首次使用的 PCCT 能提供更高的主观图像质量和更高的 CNR,而所需的辐射剂量仅为 CBCT 的近四分之一。
{"title":"Ultra-low-dose photon-counting CT of paranasal sinus: an in vivo comparison of radiation dose and image quality to cone-beam CT.","authors":"Hanns Leonhard Kaatsch, Florian Fulisch, Daniel Dillinger, Laura Kubitscheck, Benjamin V Becker, Joel Piechotka, Marc A Brockmann, Matthias F Froelich, Stefan O Schoenberg, Daniel Overhoff, Stephan Waldeck","doi":"10.1093/dmfr/twad010","DOIUrl":"10.1093/dmfr/twad010","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated the differences in subjective and objective image parameters as well as dose exposure of photon-counting CT (PCCT) compared to cone-beam CT (CBCT) in paranasal sinus imaging for the assessment of rhinosinusitis and sinonasal anatomy.</p><p><strong>Methods: </strong>This single-centre retrospective study included 100 patients, who underwent either clinically indicated PCCT or CBCT of the paranasal sinus. Two blinded experienced ENT radiologists graded image quality and delineation of specific anatomical structures on a 5-point Likert scale. In addition, contrast-to-noise ratio (CNR) and applied radiation doses were compared among both techniques.</p><p><strong>Results: </strong>Image quality and delineation of bone structures in paranasal sinus PCCT was subjectively rated superior by both readers compared to CBCT (P < .001). CNR was significantly higher for photon-counting CT (P < .001). Mean effective dose for PCCT examinations was significantly lower than for CBCT (0.038 mSv ± 0.009 vs. 0.14 mSv ± 0.011; P < .001).</p><p><strong>Conclusion: </strong>In a performance comparison of PCCT and a modern CBCT scanner in paranasal sinus imaging, we demonstrated that first-use PCCT in clinical routine provides higher subjective image quality accompanied by higher CNR at close to a quarter of the dose exposure compared to CBCT.</p>","PeriodicalId":11261,"journal":{"name":"Dento maxillo facial radiology","volume":"53 2","pages":"103-108"},"PeriodicalIF":3.3,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139706368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic accuracy of ultrasonography in relation to salivary gland biopsy in Sjögren's syndrome: a systematic review with meta-analysis. 与唾液腺活检相关的超声波检查对斯约戈伦综合征的诊断准确性:系统回顾与荟萃分析。
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-02-08 DOI: 10.1093/dmfr/twad007
Fernanda B Martins, Millena B Oliveira, Leandro M Oliveira, Alan Grupioni Lourenço, Luiz Renato Paranhos, Ana Carolina F Motta

Objectives: To evaluate the accuracy of major salivary gland ultrasonography (SGUS) in relation to minor salivary gland biopsy (mSGB) in the diagnosis of Sjögren's syndrome (SS).

Methods: A systematic review and meta-analysis were performed. Ten databases were searched to identify studies that compared the accuracy of SGUS and mSGB. The risk of bias was assessed, data were extracted, and univariate and bivariate random-effects meta-analyses were done.

Results: A total of 5000 records were identified; 13 studies were included in the qualitative synthesis and 10 in the quantitative synthesis. The first meta-analysis found a sensitivity of 0.86 (95% CI: 0.74-0.92) and specificity of 0.87 (95% CI: 0.81-0.92) for the predictive value of SGUS scoring in relation to the result of mSGB. In the second meta-analysis, mSGB showed higher sensitivity and specificity than SGUS. Sensitivity was 0.80 (95% CI: 0.74-0.85) for mSGB and 0.71 (95% CI: 0.58-0.81) for SGUS, and specificity was 0.94 (95% CI: 0.87-0.97) for mSGB and 0.89 (95% CI: 0.82-0.94) for SGUS.

Conclusions: The diagnostic accuracy of SGUS was similar to that of mSGB. SGUS is an effective diagnostic test that shows good sensitivity and high specificity, in addition to being a good tool for prognosis and for avoiding unnecessary biopsies. More studies using similar methodologies are needed to assess the accuracy of SGUS in predicting the result of mSGB. Our results will contribute to decision-making for the implementation of SGUS as a diagnostic tool for SS, considering the advantages of this method.

目的评估大唾液腺超声波检查(SGUS)与小唾液腺活检(mSGB)在诊断斯约格伦综合征(SS)方面的准确性:方法:进行了系统回顾和荟萃分析。方法:进行了一项系统综述和荟萃分析。检索了十个数据库,以确定比较 SGUS 和 mSGB 准确性的研究。评估了偏倚风险,提取了数据,并进行了单变量和双变量随机效应荟萃分析:结果:共发现了 5000 条记录;13 项研究被纳入定性综述,10 项被纳入定量综述。第一项荟萃分析发现,SGUS 评分对 mSGB 结果的预测价值的敏感性为 0.86(95% CI:0.74-0.92),特异性为 0.87(95% CI:0.81-0.92)。在第二项荟萃分析中,mSGB 比 SGUS 显示出更高的灵敏度和特异性。敏感性方面,mSGB为0.80(95% CI:0.74-0.85),SGUS为0.71(95% CI:0.58-0.81);特异性方面,mSGB为0.94(95% CI:0.87-0.97),SGUS为0.89(95% CI:0.82-0.94):SGUS的诊断准确性与mSGB相似。SGUS是一种有效的诊断检测,具有良好的灵敏度和较高的特异性,是预后和避免不必要活检的良好工具。需要使用类似方法进行更多研究,以评估 SGUS 预测 mSGB 结果的准确性。考虑到 SGUS 的优势,我们的研究结果将有助于将其作为 SS 诊断工具的决策。
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引用次数: 0
Comparison of deep learning methods for the radiographic detection of patients with different periodontitis stages. 比较深度学习方法对不同牙周炎阶段患者的放射学检测。
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-01-11 DOI: 10.1093/dmfr/twad003
Berceste Guler Ayyildiz, Rukiye Karakis, Busra Terzioglu, Durmus Ozdemir

Objectives: The objective of this study is to assess the accuracy of computer-assisted periodontal classification bone loss staging using deep learning (DL) methods on panoramic radiographs and to compare the performance of various models and layers.

Methods: Panoramic radiographs were diagnosed and classified into 3 groups, namely "healthy," "Stage1/2," and "Stage3/4," and stored in separate folders. The feature extraction stage involved transferring and retraining the feature extraction layers and weights from 3 models, namely ResNet50, DenseNet121, and InceptionV3, which were proposed for classifying the ImageNet dataset, to 3 DL models designed for classifying periodontal bone loss. The features obtained from global average pooling (GAP), global max pooling (GMP), or flatten layers (FL) of convolutional neural network (CNN) models were used as input to the 8 different machine learning (ML) models. In addition, the features obtained from the GAP, GMP, or FL of the DL models were reduced using the minimum redundancy maximum relevance (mRMR) method and then classified again with 8 ML models.

Results: A total of 2533 panoramic radiographs, including 721 in the healthy group, 842 in the Stage1/2 group, and 970 in the Stage3/4 group, were included in the dataset. The average performance values of DenseNet121 + GAP-based and DenseNet121 + GAP + mRMR-based ML techniques on 10 subdatasets and ML models developed using 2 feature selection techniques outperformed CNN models.

Conclusions: The new DenseNet121 + GAP + mRMR-based support vector machine model developed in this study achieved higher performance in periodontal bone loss classification compared to other models in the literature by detecting effective features from raw images without the need for manual selection.

研究目的本研究旨在评估使用深度学习(DL)方法对全景X光片进行计算机辅助牙周分类骨质流失分期的准确性,并比较各种模型和层的性能:对全景X光片进行诊断,并将其分为3组,即 "健康"、"1/2期 "和 "3/4期",分别存储在不同的文件夹中。特征提取阶段包括将用于ImageNet数据集分类的3个模型(即ResNet50、DenseNet121和InceptionV3)的特征提取层和权重转移到用于牙周骨质流失分类的3个DL模型,并对其进行再训练。从卷积神经网络(CNN)模型的全局平均池化(GAP)、全局最大池化(GMP)或扁平化层(FL)获得的特征被用作 8 个不同机器学习(ML)模型的输入。此外,使用最小冗余最大相关性(mRMR)方法对从卷积神经网络模型的 GAP、GMP 或 FL 中获得的特征进行缩减,然后用 8 个 ML 模型再次进行分类:数据集共包含 2533 张全景照片,其中健康组 721 张,1/2 期组 842 张,3/4 期组 970 张。基于 DenseNet121 + GAP 和基于 DenseNet121 + GAP + mRMR 的 ML 技术在 10 个子数据集上的平均性能值以及使用 2 种特征选择技术开发的 ML 模型的性能均优于 CNN 模型:本研究开发的基于 DenseNet121 + GAP + mRMR 的支持向量机模型无需人工选择,就能从原始图像中检测出有效特征,与文献中的其他模型相比,该模型在牙周骨缺失分类中取得了更高的性能。
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引用次数: 0
Skeletal facial asymmetry: reliability of manual and artificial intelligence-driven analysis. 骨骼面部不对称:人工和人工智能分析的可靠性。
IF 3.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-01-11 DOI: 10.1093/dmfr/twad006
Natalia Kazimierczak, Wojciech Kazimierczak, Zbigniew Serafin, Paweł Nowicki, Tomasz Jankowski, Agnieszka Jankowska, Joanna Janiszewska-Olszowska

Objectives: To compare artificial intelligence (AI)-driven web-based platform and manual measurements for analysing facial asymmetry in craniofacial CT examinations.

Methods: The study included 95 craniofacial CT scans from patients aged 18-30 years. The degree of asymmetry was measured based on AI platform-predefined anatomical landmarks: sella (S), condylion (Co), anterior nasal spine (ANS), and menton (Me). The concordance between the results of automatic asymmetry reports and manual linear 3D measurements was calculated. The asymmetry rate (AR) indicator was determined for both automatic and manual measurements, and the concordance between them was calculated. The repeatability of manual measurements in 20 randomly selected subjects was assessed. The concordance of measurements of quantitative variables was assessed with interclass correlation coefficient (ICC) according to the Shrout and Fleiss classification.

Results: Erroneous AI tracings were found in 16.8% of cases, reducing the analysed cases to 79. The agreement between automatic and manual asymmetry measurements was very low (ICC < 0.3). A lack of agreement between AI and manual AR analysis (ICC type 3 = 0) was found. The repeatability of manual measurements and AR calculations showed excellent correlation (ICC type 2 > 0.947).

Conclusions: The results indicate that the rate of tracing errors and lack of agreement with manual AR analysis make it impossible to use the tested AI platform to assess the degree of facial asymmetry.

目的比较人工智能(AI)驱动的网络平台和人工测量方法,以分析颅面部 CT 检查中的面部不对称情况:研究包括 95 例 18-30 岁患者的颅面部 CT 扫描。不对称程度根据 AI 平台预先定义的解剖地标进行测量:蝶鞍 (S)、髁突 (Co)、前鼻骨棘 (ANS) 和耳廓 (Me)。计算了自动不对称报告结果与手动线性三维测量结果之间的一致性。确定了自动和手动测量的不对称率(AR)指标,并计算了两者之间的一致性。对随机抽取的 20 名受试者的手动测量重复性进行了评估。根据 Shrout 和 Fleiss 分类法,使用类间相关系数(ICC)评估定量变量测量的一致性:自动和人工不对称测量的一致性非常低(ICC < 0.3)。人工智能和手动 AR 分析之间缺乏一致性(ICC 类型 3 = 0)。人工测量和 AR 计算的重复性显示出极好的相关性(ICC 类型 2 > 0.947):结果表明,由于追踪错误率和与人工 AR 分析缺乏一致性,因此无法使用测试的人工智能平台来评估面部不对称程度。
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引用次数: 0
Morphological variation of gubernacular tracts for permanent mandibular canines in eruption: a three-dimensional analysis. 恒下颌犬齿萌出时龈沟的形态变化:三维分析。
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-01-11 DOI: 10.1093/dmfr/twad008
Pei Liu, Renpeng Li, Yong Cheng, Bo Li, Lili Wei, Wei Li, Xiaolong Guo, Hang Li, Fang Wang

Objectives: This study aims to evaluate the morphological features of gubernacular tract (GT) for erupting permanent mandibular canines at different ages from 5 to 9 years old with a three-dimensional (3D) measurement method.

Methods: The cone-beam CT images of 50 patients were divided into five age groups. The 3D models of the GT for mandibular canines were reconstructed and analysed. The characteristics of the GT, including length, diameter, ellipticity, tortuosity, superficial area, volume, and the angle between the canine and GT, were evaluated using a centreline fitting algorithm.

Results: Among the 100 GTs that were examined, the length of the GT for mandibular canines decreased between the ages of 5 and 9 years, while the diameter increased until the age of 7 years. Additionally, the ellipticity and tortuosity of the GT decreased as age advanced. The superficial area and volume exhibited a trend of initially increasing and then decreasing. The morphological variations of the GT displayed heterogeneous changes during different periods.

Conclusions: The 3D measurement method effectively portrayed the morphological attributes of the GT for mandibular canines. The morphological characteristics of the GT during the eruption process exhibited significant variations. The variations in morphological changes may indicate different stages of mandibular canine eruption.

目的:本研究旨在通过三维测量方法,评估5至9岁不同年龄段下颌恒牙萌出沟的形态特征:本研究旨在通过三维(3D)测量方法,评估5至9岁不同年龄段下颌恒牙萌出沟的形态特征:方法:将 50 名患者的锥束 CT 图像分为五个年龄组。方法:将 50 名患者的锥束 CT 图像分为 5 个年龄组,重建并分析下颌犬齿 GT 的三维模型。采用中心线拟合算法评估 GT 的特征,包括长度、直径、椭圆度、迂曲度、表面积、体积以及犬齿与 GT 之间的角度:结果:在检测的 100 个牙槽骨中,下颌犬齿的牙槽骨长度在 5 到 9 岁之间有所减少,而直径在 7 岁之前有所增加。此外,随着年龄的增长,牙槽骨的椭圆度和迂曲度也在下降。表面积和体积呈现出先增大后减小的趋势。GT的形态变化在不同时期呈现出异质性变化:结论:三维测量方法有效地描述了下颌犬齿GT的形态特征。下颌犬齿GT的形态特征在萌出过程中表现出明显的变化。形态变化的差异可能预示着下颌犬牙萌出的不同阶段。
{"title":"Morphological variation of gubernacular tracts for permanent mandibular canines in eruption: a three-dimensional analysis.","authors":"Pei Liu, Renpeng Li, Yong Cheng, Bo Li, Lili Wei, Wei Li, Xiaolong Guo, Hang Li, Fang Wang","doi":"10.1093/dmfr/twad008","DOIUrl":"10.1093/dmfr/twad008","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to evaluate the morphological features of gubernacular tract (GT) for erupting permanent mandibular canines at different ages from 5 to 9 years old with a three-dimensional (3D) measurement method.</p><p><strong>Methods: </strong>The cone-beam CT images of 50 patients were divided into five age groups. The 3D models of the GT for mandibular canines were reconstructed and analysed. The characteristics of the GT, including length, diameter, ellipticity, tortuosity, superficial area, volume, and the angle between the canine and GT, were evaluated using a centreline fitting algorithm.</p><p><strong>Results: </strong>Among the 100 GTs that were examined, the length of the GT for mandibular canines decreased between the ages of 5 and 9 years, while the diameter increased until the age of 7 years. Additionally, the ellipticity and tortuosity of the GT decreased as age advanced. The superficial area and volume exhibited a trend of initially increasing and then decreasing. The morphological variations of the GT displayed heterogeneous changes during different periods.</p><p><strong>Conclusions: </strong>The 3D measurement method effectively portrayed the morphological attributes of the GT for mandibular canines. The morphological characteristics of the GT during the eruption process exhibited significant variations. The variations in morphological changes may indicate different stages of mandibular canine eruption.</p>","PeriodicalId":11261,"journal":{"name":"Dento maxillo facial radiology","volume":"53 1","pages":"60-66"},"PeriodicalIF":2.9,"publicationDate":"2024-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11003659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139424477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Dento maxillo facial radiology
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