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Variations in head tilt during the acquisition of cone beam computed tomography scans and their effects on effective radiation dose. 采集 CBCT 扫描时头部倾斜度的变化及其对有效辐射剂量的影响。
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-11-01 DOI: 10.1093/dmfr/twae043
Arthur X M Mancini, Gabriela A Carmozini, Thiago M Inácio, Marcela T Réa, Cassiana Viccari, Danieli M Brasil, Christiano Oliveira-Santos

Objectives: This study evaluated the impact of variations in anteroposterior and lateral tilts of patients head on radiation-weighted doses to organs/tissues and effective doses using 3 different cone beam computed tomography (CBCT) machines.

Methods: An anthropomorphic phantom was used to estimate radiation doses in 3 CBCT machines (OP300, Eagle X 3D, and Eagle Edge). Thermoluminescent dosimeters were placed in regions corresponding to pre-stablished organ/tissues. CBCT examinations from the posterior mandible and anterior maxilla regions were acquired, with 3 different anteroposterior angulations (0°, 30°, and 45°), and from the posterior mandible in 3 different lateral angulations (0°, 20° to the left, and 20° to the right side). Radiation-weighted doses for each organ/tissue and effective doses were calculated for each machine and angulation.

Results: For the posterior mandible acquisitions, anteroposterior angulations of the head at 30° and 45° yielded a reduction in effective doses in all 3 devices. A 20° tilt to the right side resulted in lower doses than to the left [same side as the field of view (FOV)]. For the anterior maxilla, increased anteroposterior angulation was associated with reduction in effective dose in 2 devices.

Conclusions: Effective doses are lower when small FOV CBCT exams of the posterior mandible and anterior maxilla are acquired with increased anteroposterior head angulation at 30° and 45°. For FOV in the posterior mandible, a 20° lateral tilt towards the side opposite to the FOV also yields lower effective doses. The main contribution to these dose reductions is the decrease in dose to salivary glands.

研究目的本研究评估了使用三种不同的锥形束计算机断层扫描机时,患者头部前倾和侧倾的变化对器官/组织辐射加权剂量和有效剂量的影响:使用一个拟人化模型来估算三台 CBCT 机(OP300、Eagle X 3D 和 Eagle Edge)的辐射剂量。热释光剂量计被放置在与预先设定的器官/组织相对应的区域。下颌骨后部和上颌骨前部的 CBCT 检查采用了三种不同的前后角度(0°、30° 和 45°),下颌骨后部的 CBCT 检查采用了三种不同的侧向角度(0°、向左 20°、向右 20°)。计算了每个器官/组织的辐射加权剂量以及每个机器和角度的有效剂量:结果:在下颌骨后部采集中,头部前后成角 30°和 45°可减少所有三种设备的有效剂量。向右侧倾斜 20°的剂量低于向左侧倾斜的剂量(与 FOV 相同)。就上颌骨前部而言,增加前胸角度与两种设备的有效剂量减少有关:结论:对下颌后部和上颌前部进行小视场CBCT检查时,如果增加头部前胸角度(30°和45°),则有效剂量会降低。对于下颚后部的 FOV,向 FOV 相反的一侧侧倾 20° 也会降低有效剂量。这些剂量降低的主要原因是唾液腺的剂量减少。
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引用次数: 0
Scout images acquired prior to cone beam CT acquisitions: reproducibility of findings and added diagnostic information. 在锥形束 CT 采集前获取的 Scout 图像:结果的再现性和附加诊断信息。
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-11-01 DOI: 10.1093/dmfr/twae039
Jennifer Christensen, Louise Hauge Matzen, Mette Hedegaard, Rubens Spin-Neto

Objectives: The aim of the present study was to assess the reproducibility of findings in cone beam CT (CBCT) scout images. Furthermore, the study aimed to assess whether a scout image shows pathology not seen within the CBCT volume (ie, added diagnostic information) and therefore must be assessed on the same terms as the full volume.

Methods: Using a retrospective design, 233 CBCT reports and scout images were assessed. Kappa statistics and percentage of accordance were used to evaluate intra- and inter-observer reproducibility as well as agreement between scout and CBCT report.

Results: Intra- and inter-observer reproducibility was overall low (kappa ranging from -0.008 to 1.000). Agreement between findings reported in the CBCT and scout was also low. One hundred fourteen impacted teeth, one apical periodontitis, and two sinus conditions seen in the scout image were not registered in the full volume report due to the extended size of the scout image.

Conclusions: Reproducibility of findings in scout images compared to CBCT volumes was low, and the scout showed very little additional diagnostic information.

Advances in knowledge: This study shows that although the reproducibility of viewing scout images is low, rare findings can go undetected if the scout is not assessed. Legislation regarding interpretation of scout images needs to be discussed.

研究目的本研究旨在评估锥形束计算机断层扫描(CBCT)探查图像结果的可重复性。此外,该研究还旨在评估锥形束计算机断层扫描(CBCT)扫描图像是否显示了CBCT容积内未见的病理变化(即增加了诊断信息),因此必须以与全容积相同的条件进行评估:方法: 采用回顾性设计,对 233 份 CBCT 报告和探查图像进行了评估。方法:采用回顾性设计对 233 份 CBCT 报告和探查图像进行评估,使用 Kappa 统计量和符合百分比来评估观察者内部和观察者之间的可重复性以及探查图像和 CBCT 报告之间的一致性:结果:观察者内部和观察者之间的再现性总体较低(卡帕范围在-0.008 到 1.000 之间)。CBCT 和探查报告结果之间的一致性也很低。由于探查图像的尺寸较大,在探查图像中发现的114颗阻生牙、1个根尖牙周炎和2个窦的情况没有记录在全量报告中:结论:与 CBCT 容量相比,探查图像结果的再现性很低,而且探查图像几乎没有显示额外的诊断信息:这项研究表明,虽然观察探查图像的再现性很低,但如果不对探查图像进行评估,罕见的发现可能会被忽略。需要讨论有关解释探查图像的立法。
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引用次数: 0
An attempt to generate panoramic radiographs including jaw cysts using StyleGAN3. 尝试使用 StyleGAN3 生成包括颌骨囊肿在内的全景 X 光片。
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-11-01 DOI: 10.1093/dmfr/twae044
Motoki Fukuda, Shinya Kotaki, Michihito Nozawa, Kaname Tsuji, Masahiro Watanabe, Hironori Akiyama, Yoshiko Ariji

Objectives: The purpose of this study was to generate radiographs including dentigerous cysts by applying the latest generative adversarial network (GAN; StyleGAN3) to panoramic radiography.

Methods: A total of 459 cystic lesions were selected, and 409 images were randomly assigned as training data and 50 images as test data. StyleGAN3 training was performed for 500 000 images. Fifty generated images were objectively evaluated by comparing them with 50 real images according to four metrics: Fréchet inception distance (FID), kernel inception distance (KID), precision and recall, and inception score (IS). A subjective evaluation of the generated images was performed by three specialists who compared them with the real images in a visual Turing test.

Results: The results of the metrics were as follows: FID, 199.28; KID, 0.14; precision, 0.0047; recall, 0.00; and IS, 2.48. The overall results of the visual Turing test were 82.3%. No significant difference was found in the human scoring of root resorption.

Conclusions: The images generated by StyleGAN3 were of such high quality that specialists could not distinguish them from the real images.

研究目的本研究的目的是将最新的生成对抗网络(GAN;StyleGAN3)应用于全景放射摄影,生成包括齿槽囊肿在内的放射影像:方法:共选取 459 个囊肿病灶,随机分配 409 张图像作为训练数据,50 张图像作为测试数据。对 500 000 张图像进行了 StyleGAN3 训练。将生成的 50 张图像与 50 张真实图像进行比较,根据四项指标对生成的图像进行客观评估:弗雷谢特起始距离(FID)、核起始距离(KID)、精确度和召回率以及起始分数(IS)。三位专家对生成的图像进行了主观评价,他们在视觉图灵测试中将生成的图像与真实图像进行了比较:指标结果如下:FID,199.28;KID,0.14;精确度,0.0047;召回率,0.00;IS,2.48。视觉图灵测试的总体结果为 82.3%。人类对牙根吸收的评分没有发现明显差异:StyleGAN3生成的图像质量非常高,专家们无法将其与真实图像区分开来。
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引用次数: 0
Using cone-beam CT for appropriate nostril selection in nasotracheal intubation. 使用锥形束计算机断层扫描在鼻气管插管中选择合适的鼻孔。
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1093/dmfr/twae038
Funda Arun, Derya Icoz, Ahmet Akti, Gokhan Gurses

Objectives: Nasotracheal intubation is a standard blind procedure associated with various complications. The selection of the appropriate nostril is crucial to preventing most of these complications. The present study aimed to evaluate the predictive ability of cone-beam CT (CBCT) images to select the correct nostril for nasotracheal intubation.

Methods: The study encompassed 60 patients who underwent maxillofacial surgery with nasotracheal intubation under general anaesthesia. While the anaesthetist made the appropriate nostril selection clinically according to a simple occlusion test and spatula test, the radiologist made the selection after analysing various CBCT findings such as the angle and direction of nasal septum deviation (NSD), minimum bone distance along the intubation path, and the presence of inferior turbinate hypertrophy. The appropriateness of these choices made blindly at different times was evaluated using descriptive statistics, chi-squared test, and independent samples t-test.

Results: The study found that 83.3% of the suggested nostril intubations were successful. We also observed that intubation duration was longer when inferior turbinate hypertrophy was present (P = .031). However, there was no statistical relationship between the presence of epistaxis and septal deviation (P = .395). Nonetheless, in 64.3% of cases with epistaxis, the intubated nostril and the septum deviation direction were the same.

Conclusions: Pre-operative evaluations using CBCT can aid anaesthetists for septum deviation and turbinate hypertrophy, as both can impact intubation success rates and duration.

目的:鼻气管插管是一种标准的盲插术,会引起各种并发症。选择合适的鼻孔对于预防大多数并发症至关重要。本研究旨在评估 CBCT 图像对选择正确鼻孔进行鼻气管插管的预测能力:研究涵盖了 60 名在全身麻醉下接受颌面手术并进行鼻气管插管的患者。麻醉师在临床上根据简单的咬合试验和刮匙试验选择合适的鼻孔,而放射科医生则在分析了各种 CBCT 结果(如鼻中隔偏曲(NSD)的角度和方向、插管路径上的最小骨距以及是否存在下鼻甲肥大)后做出选择。研究使用描述性统计、卡方检验和独立样本 t 检验评估了不同时间盲法选择的适当性:研究发现,83.3% 的建议鼻孔插管成功。我们还观察到,下鼻甲肥大时插管持续时间较长(p = 0.031)。然而,鼻衄与鼻中隔偏曲之间没有统计学关系(p = 0.395)。然而,在 64.3% 的鼻衄病例中,插管鼻孔和鼻中隔偏曲的方向是一致的:结论:使用 CBCT 进行术前评估有助于麻醉师发现鼻中隔偏曲和鼻甲肥大,因为两者都会影响插管成功率和持续时间。
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引用次数: 0
In vitro accuracy of ultra-low dose cone-beam CT for detection of proximal caries. 超低剂量锥形束计算机断层扫描在体外检测近端龋齿的准确性。
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1093/dmfr/twae030
Aria Taeby, Seyyed Amir Seyyedi, Maryam Mostafavi

Objectives: This study aimed to assess the accuracy of ultra-low dose (ULD) cone-beam CT (CBCT) for detection of proximal caries.

Methods: This in vitro study evaluated 104 molar and premolar teeth. The teeth were mounted in dry skulls and underwent CBCT with 4 protocols of high-resolution (HR), normal (NORM), ULD-HR, and ULD-NORM; 78 CBCT images were scored by 3 observers for the presence and penetration depth of caries twice with a 2-week interval using a 5-point Likert scale. The teeth were then sectioned and observed under a stereomicroscope (gold standard). The 4 protocols were compared with each other and with the gold standard. The receiver operating characteristic curve was drawn, and the area under the curve (AUC) was calculated and compared by the Chi-square test (alpha = .05).

Results: The interobserver agreement ranged from 0.5233 to 0.6034 for ULD-NORM, 0.5380 to 0.6279 for NORM, 0.5856 to 0.6300 for ULD-HR, and 0.6614 to 0.7707 for HR images. The intra-observer agreement ranged from 0.6027 to 0.8812 for ULD-HR, 0.7083 to 0.7556 for HR, 0.6076 to 0.9452 for ULD-NORM, and 0.7012 to 0.9221 for NORM images. Comparison of AUC revealed no significant difference between NORM and ULD-NORM (P > .05), or HR and ULD-HR (P > .05). The highest AUC belonged to HR (0.8529) and the lowest to NORM (0.7774).

Conclusions: Considering the significant reduction in radiation dose in ULD CBCT and its acceptable diagnostic accuracy for detection of proximal caries, this protocol may be used for detection of proximal carious lesions and assessment of their depth.

研究目的本研究旨在评估超低剂量(ULD)锥束计算机断层扫描(CBCT)检测近端龋的准确性:这项体外研究评估了 104 颗臼齿和前臼齿。这些牙齿被安装在干燥的头骨中,并接受了高分辨率 (HR)、正常 (NORM)、ULD-HR 和 ULD-NORM 四种方案的 CBCT 扫描;78 张 CBCT 图像由三名观察者使用 5 点李克特量表对龋齿的存在和穿透深度进行两次评分,每次间隔 2 周。然后在体视显微镜(金标准)下对牙齿进行切片和观察。将四种方案相互比较,并与金标准进行比较。绘制接收器操作特征曲线(ROC),计算曲线下面积(AUC),并通过卡方检验(α=0.05)进行比较:ULD-NORM的观察者间一致性为0.5233至0.6034,NORM为0.5380至0.6279,ULD-HR为0.5856至0.6300,HR图像为0.6614至0.7707。ULD-HR 的观察者内部一致性为 0.6027 至 0.8812,HR 为 0.7083 至 0.7556,ULD-NORM 为 0.6076 至 0.9452,NORM 为 0.7012 至 0.9221。比较 AUC 发现,NORM 与 ULD-NORM 之间(P > 0.05)或 HR 与 ULD-HR 之间(P > 0.05)无显著差异。AUC最高的是HR(0.8529),最低的是NORM(0.7774):考虑到 ULD CBCT 的辐射剂量明显降低,且其对近端龋病检测的诊断准确性可以接受,该方案可用于近端龋病病变的检测及其深度评估。
{"title":"In vitro accuracy of ultra-low dose cone-beam CT for detection of proximal caries.","authors":"Aria Taeby, Seyyed Amir Seyyedi, Maryam Mostafavi","doi":"10.1093/dmfr/twae030","DOIUrl":"10.1093/dmfr/twae030","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to assess the accuracy of ultra-low dose (ULD) cone-beam CT (CBCT) for detection of proximal caries.</p><p><strong>Methods: </strong>This in vitro study evaluated 104 molar and premolar teeth. The teeth were mounted in dry skulls and underwent CBCT with 4 protocols of high-resolution (HR), normal (NORM), ULD-HR, and ULD-NORM; 78 CBCT images were scored by 3 observers for the presence and penetration depth of caries twice with a 2-week interval using a 5-point Likert scale. The teeth were then sectioned and observed under a stereomicroscope (gold standard). The 4 protocols were compared with each other and with the gold standard. The receiver operating characteristic curve was drawn, and the area under the curve (AUC) was calculated and compared by the Chi-square test (alpha = .05).</p><p><strong>Results: </strong>The interobserver agreement ranged from 0.5233 to 0.6034 for ULD-NORM, 0.5380 to 0.6279 for NORM, 0.5856 to 0.6300 for ULD-HR, and 0.6614 to 0.7707 for HR images. The intra-observer agreement ranged from 0.6027 to 0.8812 for ULD-HR, 0.7083 to 0.7556 for HR, 0.6076 to 0.9452 for ULD-NORM, and 0.7012 to 0.9221 for NORM images. Comparison of AUC revealed no significant difference between NORM and ULD-NORM (P > .05), or HR and ULD-HR (P > .05). The highest AUC belonged to HR (0.8529) and the lowest to NORM (0.7774).</p><p><strong>Conclusions: </strong>Considering the significant reduction in radiation dose in ULD CBCT and its acceptable diagnostic accuracy for detection of proximal caries, this protocol may be used for detection of proximal carious lesions and assessment of their depth.</p>","PeriodicalId":11261,"journal":{"name":"Dento maxillo facial radiology","volume":" ","pages":"459-467"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141558308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Automatic classification and segmentation of multiclass jaw lesions in cone-beam CT using deep learning. 利用深度学习对锥形束计算机断层扫描中的多类颌骨病变进行自动分类和分割。
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1093/dmfr/twae028
Wei Liu, Xiang Li, Chang Liu, Ge Gao, Yutao Xiong, Tao Zhu, Wei Zeng, Jixiang Guo, Wei Tang

Objectives: To develop and validate a modified deep learning (DL) model based on nnU-Net for classifying and segmenting five-class jaw lesions using cone-beam CT (CBCT).

Methods: A total of 368 CBCT scans (37 168 slices) were used to train a multi-class segmentation model. The data underwent manual annotation by two oral and maxillofacial surgeons (OMSs) to serve as ground truth. Sensitivity, specificity, precision, F1-score, and accuracy were used to evaluate the classification ability of the model and doctors, with or without artificial intelligence assistance. The dice similarity coefficient (DSC), average symmetric surface distance (ASSD), and segmentation time were used to evaluate the segmentation effect of the model.

Results: The model achieved the dual task of classifying and segmenting jaw lesions in CBCT. For classification, the sensitivity, specificity, precision, and accuracy of the model were 0.871, 0.974, 0.874, and 0.891, respectively, surpassing oral and maxillofacial radiologists (OMFRs) and OMSs, approaching the specialist. With the model's assistance, the classification performance of OMFRs and OMSs improved, particularly for odontogenic keratocyst (OKC) and ameloblastoma (AM), with F1-score improvements ranging from 6.2% to 12.7%. For segmentation, the DSC was 87.2% and the ASSD was 1.359 mm. The model's average segmentation time was 40 ± 9.9 s, contrasting with 25 ± 7.2 min for OMSs.

Conclusions: The proposed DL model accurately and efficiently classified and segmented five classes of jaw lesions using CBCT. In addition, it could assist doctors in improving classification accuracy and segmentation efficiency, particularly in distinguishing confusing lesions (eg, AM and OKC).

目的开发并验证基于 nnU-net 的改进型深度学习(DL)模型,用于使用锥束计算机断层扫描(CBCT)对五类颌骨病变进行分类和分割:共使用了 368 次 CBCT 扫描(37 168 个切片)来训练多类分割模型。数据由两名口腔颌面外科医生(OMS)进行人工标注,作为基本真相。灵敏度、特异性、精确度、F1-分数和准确度用于评估模型和医生的分类能力,无论是否有人工智能辅助。骰子相似系数(DSC)、平均对称面距离(ASSD)和分割时间用于评估模型的分割效果:结果:该模型实现了在 CBCT 中对颌骨病变进行分类和分割的双重任务。在分类方面,模型的灵敏度、特异度、精确度和准确度分别为 0.871、0.974、0.874 和 0.891,超过了口腔颌面放射医师(OMFR)和 OMS,接近专科医师。在该模型的帮助下,口腔颌面部放射医师和口腔颌面部放射医师的分类性能有所提高,尤其是牙源性角化囊肿(OKC)和釉母细胞瘤(AM),F1 分数提高了 6.2% 到 12.7%。在分割方面,DSC 为 87.2%,ASSD 为 1.359 毫米。该模型的平均分割时间为 40 ± 9.9 秒,与 OMSs 的 25 ± 7.2 分钟形成鲜明对比:结论:所提出的 DL 模型利用 CBCT 准确、高效地对五类颌骨病变进行了分类和分割。此外,它还能帮助医生提高分类准确性和分割效率,尤其是在区分易混淆病变(如 AM 和 OKC)方面。
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引用次数: 0
Enhanced multistage deep learning for diagnosing anterior disc displacement in the temporomandibular joint using MRI. 利用磁共振成像诊断颞下颌关节前椎间盘移位的增强型多级深度学习。
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1093/dmfr/twae033
Chang-Ki Min, Won Jung, Subin Joo

Objectives: This study aimed to propose a new method for the automatic diagnosis of anterior disc displacement of the temporomandibular joint (TMJ) using MRI and deep learning. By using a multistage approach, the factors affecting the final result can be easily identified and improved.

Methods: This study introduces a multistage automatic diagnostic technique using deep learning. This process involves segmenting the target from MR images, extracting distance parameters, and classifying the diagnosis into 3 classes. MRI exams of 368 TMJs from 204 patients were evaluated for anterior disc displacement. In the first stage, 5 algorithms were used for the semantic segmentation of the disc and condyle. In the second stage, 54 distance parameters were extracted from the segments. In the third stage, a rule-based decision model was developed to link the parameters with the expert diagnosis results.

Results: In the first stage, DeepLabV3+ showed the best result (95% Hausdorff distance, Dice coefficient, and sensitivity of 6.47 ± 7.22, 0.84 ± 0.07, and 0.84 ± 0.09, respectively). This study used the original MRI exams as input without preprocessing and showed high segmentation performance compared with that of previous studies. In the third stage, the combination of SegNet and a random forest model yielded an accuracy of 0.89 ± 0.06.

Conclusions: An algorithm was developed to automatically diagnose TMJ-anterior disc displacement using MRI. Through a multistage approach, this algorithm facilitated the improvement of results and demonstrated high accuracy from more complex inputs. Furthermore, existing radiological knowledge was applied and validated.

研究目的本研究旨在提出一种利用磁共振成像(MRI)和深度学习自动诊断颞下颌关节(TMJ)前椎间盘移位的新方法。通过采用多阶段方法,可以轻松识别并改进影响最终结果的因素:本研究介绍了一种使用深度学习的多阶段自动诊断技术。该过程包括从磁共振图像中分割目标、提取距离参数并将诊断结果分为三类。对 204 名患者的 368 个颞下颌关节的 MRI 检查进行了椎间盘前移位评估。在第一阶段,使用五种算法对椎间盘和髁状突进行语义分割。第二阶段,从分段中提取 54 个距离参数。在第三阶段,开发了一个基于规则的决策模型,将参数与专家诊断结果联系起来:在第一阶段,DeepLabV3+ 的结果最好(95% Hausdorff 距离、Dice 系数和灵敏度分别为 6.47 ± 7.22、0.84 ± 0.07 和 0.84 ± 0.09)。该研究使用原始核磁共振成像检查作为输入,未进行预处理,与之前的研究相比,显示出较高的分割性能。在第三阶段,结合 SegNet 和随机森林模型得出的准确率为 0.89 ± 0.06:利用核磁共振成像开发了一种自动诊断颞下颌关节前盘移位的算法。通过多阶段方法,该算法促进了结果的改进,并从更复杂的输入中显示出较高的准确性。此外,现有的放射学知识也得到了应用和验证。
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引用次数: 0
The diagnostic value of prostate-specific membrane antigen PET-CT in differentiating medication-related osteonecrosis of the jaw and metastasis to the jawbone. PSMA PET-CT 在鉴别药物性颌骨骨坏死和颌骨转移方面的诊断价值。
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1093/dmfr/twae034
Karin Kur, Erofili Papadopoulou, Meital Nidam, Michal Fertouk, Omer Binyamini, Silvina Friedlander Barenboim, Towy Sorel Lazarovitci, Liran Domachevsky, Noam Yarom

Introduction: Medication-related osteonecrosis of the jaw (MRONJ) and jaw metastasis might share similar clinical and radiographic characteristics, with both demonstrating F-18 fluorodeoxyglucose (FDG) uptake on PET-CT. Prostate-specific membrane antigen (PSMA) PET-CT is used to demonstrate prostate cancer dissemination. Unlike FDG PET-CT, PSMA PET-CT is more specific to cancer than to inflammation. Therefore, we hypothesized that it might be a useful tool to differentiate between MRONJ and jaw metastasis.

Methods: All files of prostate cancer patients diagnosed with MRONJ and with available PSMA PET-CT studies were retrieved. A similar number of solid cancer patients with MRONJ and with available FDG PET-CT studies served as a second study group. All studies were reviewed by 2 blinded co-investigators (L.D. and M.F.).

Results: Seventeen patients who underwent PSMA PET-CT (24 studies) and 15 patients who underwent FDG PET-CT (29 studies) met the inclusion criteria. All patients with FDG PET-CT studies showed pathological uptake at the site of MRONJ in at least one of their studies versus only 23.5% of patients in the PSMA PET-CT group (P < .001). FDG PET-CT studies showed pathological uptake in 89.6% of the studies compared with only 20.8% in the PSMA PET-CT group (P < .001). The mean standardized uptake value (SUVmax) and the mean uptake volume in the FDG PET-CT group were significantly higher compared with the PSMA PET-CT group (P < .001 and P < .005, respectively). The interclass correlation coefficient for all parameters was higher than 0.95.

Conclusions: PSMA PET-CT is useful to differentiate between MRONJ and jaw metastasis.

导言:药物相关性颌骨坏死(MRONJ)和颌骨转移可能具有相似的临床和影像学特征,两者在 PET-CT 上均显示 FDG 摄取。前列腺特异性膜抗原(PSMA)PET-CT用于显示前列腺癌的扩散。与 FDG PET-CT 不同,PSMA PET-CT 对癌症的特异性高于对炎症的特异性。因此,我们假设它可能是区分 MRONJ 和颌骨转移的有用工具:我们检索了所有确诊为 MRONJ 并进行过 PSMA PET-CT 研究的前列腺癌患者的档案。同样数量的患有 MRONJ 并可进行 FDG PET-CT 研究的实体癌患者作为第二组研究对象。所有研究均由两名盲法共同研究者(LD、MF)进行审查:17名接受 PSMA PET-CT 检查的患者(24 项研究)和 15 名接受 FDG PET-CT 检查的患者(29 项研究)符合纳入标准。所有接受 FDG PET-CT 研究的患者至少有一项研究显示 MRONJ 位点存在病理摄取,而 PSMA PET-CT 组仅有 23.5% 的患者显示 MRONJ 位点存在病理摄取(P 结论:PSMA PET-CT 对肺癌的诊断非常有用:PSMA PET-CT 可用于区分 MRONJ 和颌骨转移。
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引用次数: 0
Hypervigilance to pain and sleep quality are confounding variables in the infrared thermography examination of the temporomandibular joint and temporal and masseter muscles. 对疼痛的过度警觉和睡眠质量是颞下颌关节、颞肌和颌下肌红外热成像检查的干扰变量。
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1093/dmfr/twae032
Erasmo Freitas de Souza Junior, Camila Maia Vieira Pereira, Jussara da Silva Barbosa, Maria Jacinta Arêa Leão Lopes Araújo Arruda, Daniela Pita de Melo, Patrícia Meira Bento

Objectives: Verify whether hypervigilance to pain (HP) and sleep quality (SQ) are confounding variables in the infrared thermography (IT) examination of the temporomandibular joint and temporal and masseter muscles.

Methods: A cross-sectional and analytical study was conducted, collecting HP and SQ data from 80 participants without temporomandibular disorders (TMD), performing their IT and another 40 participants with TMD. For the selection of participants with and without TMD, the TMD Pain Screener questionnaire and axis I of the Diagnostic Criteria for Temporomandibular Disorders were applied. SQ was verified using the Pittsburgh Sleep Quality Index (PSQI) questionnaire. For the HP assessment the Pain Vigilance and Awareness Questionnaire (PVAQ) was applied. And the IT was performed through a FLIR infrared sensor camera, model T650 Infrared.

Results: No significant correlations were found between SQ and the temperatures of the areas of interest (P > .05), and regarding HP, a statistically significant positive correlation was found with the dimensionless (ρ = 0.289) and non-dimensionless (ρ = 0.223) asymmetries of temporal muscle temperatures. In the temperature comparisons between the participants without TMD and the participants with TMD, significant differences were found (P < .05), also when the group without TMD was controlled according to both HP and SQ (P < .05), with higher temperatures found in the TMD group.

Conclusions: HP and SQ can be considered confounding variables in IT examination of the temporomandibular region.

目的:验证疼痛过度警觉(HP)和睡眠质量(SQ)是否是红外热成像(IT)检查的干扰变量:验证疼痛过度警觉(HP)和睡眠质量(SQ)是否是颞下颌关节、颞肌和颌下肌肉红外热成像(IT)检查的干扰变量:我们进行了一项横断面分析研究,收集了80名无颞下颌关节紊乱症(TMD)的患者在进行IT检查时的HP和SQ数据,以及另外40名TMD患者的HP和SQ数据。在选择有 TMD 和无 TMD 的参与者时,采用了 TMD 疼痛筛查问卷和颞下颌关节紊乱诊断标准 I 轴。使用匹兹堡睡眠质量指数(PSQI)问卷对睡眠质量进行验证。HP评估采用了疼痛警觉和意识问卷(PVAQ)。信息技术是通过 FLIR T650 红外感应相机进行的:结果:SQ 与相关区域的温度之间没有发现明显的相关性(P > 0.05),而在 HP 方面,发现与颞肌温度的无量纲(ρ = 0.289)和非无量纲(ρ = 0.223)不对称存在统计学意义上的明显正相关。在无 TMD 参与者与有 TMD 参与者之间的温度比较中,发现了显著差异(p 结论:TMD 患者的颞部肌肉温度与无 TMD 参与者的颞部肌肉温度存在显著差异:在对颞下颌区域进行红外热成像检查时,HP 和 SQ 可被视为混杂变量。
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引用次数: 0
New scenarios for training in oral radiology: clinical performance and predoctoral students' perception of 3D-printed mannequins. 口腔放射学培训的新场景:三维打印人体模型的临床表现和博士预科生的感知。
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1093/dmfr/twae035
Wislem Miranda de Mello, Vinícius Dutra, Lucas Machado Maracci, Gleica Dal' Ongaro Savegnago, Geraldo Fagundes Serpa, Gabriela Salatino Liedke

Objectives: This study aimed to evaluate the impact of 3D-printed mannequins on the training of predoctoral students.

Methods: Two 3D-printed training models were developed: a traditional model that simulates a sound adult patient and a customized model with pathological and physiological changes (impacted third molar and edentulous region). Students accomplished their pre-clinical training divided into a control group (CG, n = 23), which had access to the traditional model, and a test group (TG, n = 20), which had access to both models. Afterward, they performed a full mouth series on patients and filled out a perception questionnaire. Radiographs were evaluated for technical parameters. Descriptive statistics and the Mann-Whitney test were used to compare the groups.

Results: Students provided positive feedback regarding the use of 3D printing. The TG reported a more realistic training experience than the CG (P = .037). Both groups demonstrated good clinical performance (CG = 7.41; TG = 7.52), and no significant differences were observed between them.

Conclusions: 3D printing is an option for producing simulators for pre-clinical training in Oral Radiology, reducing student stress and increasing confidence during clinical care.

研究目的本研究旨在评估三维打印人体模型对博士前期学生培训的影响:开发了两种三维打印训练模型:一种是模拟健全成人患者的传统模型,另一种是具有病理和生理变化的定制模型(影响第三磨牙和无牙颌区域)。学生在完成临床前培训后分为对照组(CG,n = 23)和测试组(TG,n = 20),前者可使用传统模型,后者可使用两种模型。之后,他们为患者进行了全口系列检查,并填写了感知问卷。对放射照片的技术参数进行评估。使用描述性统计和曼-惠特尼检验对各组进行比较:结果:学生们对 3D 打印的使用给予了积极反馈。TG组比CG组获得了更真实的培训体验(p = 0.037)。两组学生均表现出良好的临床表现(CG = 7.41;TG = 7.52),两组学生之间未发现明显差异:3D打印是制作口腔放射学临床前培训模拟器的一种选择,可以减轻学生的压力,增强临床护理的信心。
{"title":"New scenarios for training in oral radiology: clinical performance and predoctoral students' perception of 3D-printed mannequins.","authors":"Wislem Miranda de Mello, Vinícius Dutra, Lucas Machado Maracci, Gleica Dal' Ongaro Savegnago, Geraldo Fagundes Serpa, Gabriela Salatino Liedke","doi":"10.1093/dmfr/twae035","DOIUrl":"10.1093/dmfr/twae035","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate the impact of 3D-printed mannequins on the training of predoctoral students.</p><p><strong>Methods: </strong>Two 3D-printed training models were developed: a traditional model that simulates a sound adult patient and a customized model with pathological and physiological changes (impacted third molar and edentulous region). Students accomplished their pre-clinical training divided into a control group (CG, n = 23), which had access to the traditional model, and a test group (TG, n = 20), which had access to both models. Afterward, they performed a full mouth series on patients and filled out a perception questionnaire. Radiographs were evaluated for technical parameters. Descriptive statistics and the Mann-Whitney test were used to compare the groups.</p><p><strong>Results: </strong>Students provided positive feedback regarding the use of 3D printing. The TG reported a more realistic training experience than the CG (P = .037). Both groups demonstrated good clinical performance (CG = 7.41; TG = 7.52), and no significant differences were observed between them.</p><p><strong>Conclusions: </strong>3D printing is an option for producing simulators for pre-clinical training in Oral Radiology, reducing student stress and increasing confidence during clinical care.</p>","PeriodicalId":11261,"journal":{"name":"Dento maxillo facial radiology","volume":" ","pages":"501-508"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141632904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Dento maxillo facial radiology
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