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Differentiation of salivary gland tumours using diffusion-weighted image-based virtual MR elastography: a pilot study. 利用基于弥散加权图像的虚拟磁共振弹性成像技术区分涎腺肿瘤:试点研究。
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-04-29 DOI: 10.1093/dmfr/twae010
Hye Na Jung, Inseon Ryoo, Sangil Suh, Byungjun Kim, Sung-Hye You, Eunju Kim

Objectives: Differentiation among benign salivary gland tumours, Warthin tumours (WTs), and malignant salivary gland tumours is crucial to treatment planning and predicting patient prognosis. However, differentiation of those tumours using imaging findings remains difficult. This study evaluated the usefulness of elasticity determined from diffusion-weighted image (DWI)-based virtual MR elastography (MRE) compared with conventional magnetic resonance imaging (MRI) findings in differentiating the tumours.

Methods: This study included 17 benign salivary gland tumours, 6 WTs, and 11 malignant salivary gland tumours scanned on neck MRI. The long and short diameters, T1 and T2 signal intensities, tumour margins, apparent diffusion coefficient (ADC) values, and elasticity from DWI-based virtual MRE of the tumours were evaluated. The interobserver agreement in measuring tumour elasticity and the receiver operating characteristic (ROC) curves were also assessed.

Results: The long and short diameters and the T1 and T2 signal intensities showed no significant difference among the 3 tumour groups. Tumour margins and the mean ADC values showed significant differences among some tumour groups. The elasticity from virtual MRE showed significant differences among all 3 tumour groups and the interobserver agreement was excellent. The area under the ROC curves of the elasticity were higher than those of tumour margins and mean ADC values.

Conclusion: Elasticity values based on DWI-based virtual MRE of benign salivary gland tumours, WTs, and malignant salivary gland tumours were significantly different. The elasticity of WTs was the highest and that of benign tumours was the lowest. The elasticity from DWI-based virtual MRE may aid in the differential diagnosis of salivary gland tumours.

目的:区分良性唾液腺肿瘤、Warthin 肿瘤和恶性唾液腺肿瘤对于制定治疗计划和预测患者预后至关重要。然而,利用影像学检查结果对这些肿瘤进行鉴别仍然很困难。本研究评估了基于弥散加权成像(DWI)的虚拟磁共振弹性成像(MRE)与传统磁共振成像结果相比在鉴别肿瘤方面的实用性:本研究包括通过颈部磁共振成像扫描的 17 个良性唾液腺肿瘤、6 个 Warthin 肿瘤和 11 个恶性唾液腺肿瘤。对肿瘤的长径和短径、T1和T2信号强度、肿瘤边缘、ADC值和基于DWI的虚拟MRE的弹性进行了评估。同时还评估了测量肿瘤弹性的观察者间一致性和 ROC 曲线:结果:三组肿瘤的长径和短径以及 T1 和 T2 信号强度无显著差异。肿瘤边缘和平均 ADC 值在某些肿瘤组之间存在显著差异。虚拟 MRE 的弹性在三组肿瘤中均有显著差异,观察者之间的一致性非常好。弹性的 ROC 曲线下面积高于肿瘤边缘和平均 ADC 值:结论:基于 DWI 虚拟 MRE 的良性涎腺肿瘤、Warthin 肿瘤和恶性涎腺肿瘤的弹性值存在显著差异。疣状肿瘤的弹性值最高,良性肿瘤的弹性值最低。基于 DWI 的虚拟 MRE 的弹性有助于涎腺肿瘤的鉴别诊断。
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引用次数: 0
An ultrasound-based histogram analysis model for prediction of tumour stroma ratio in pleomorphic adenoma of the salivary gland. 预测唾液腺多形性腺瘤肿瘤基质比例的超声直方图分析模型
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-04-29 DOI: 10.1093/dmfr/twae006
Huan-Zhong Su, Yu-Hui Wu, Long-Cheng Hong, Kun Yu, Mei Huang, Yi-Ming Su, Feng Zhang, Zuo-Bing Zhang, Xiao-Dong Zhang

Objectives: Preoperative identification of different stromal subtypes of pleomorphic adenoma (PA) of the salivary gland is crucial for making treatment decisions. We aimed to develop and validate a model based on histogram analysis (HA) of ultrasound (US) images for predicting tumour stroma ratio (TSR) in salivary gland PA.

Methods: A total of 219 PA patients were divided into low-TSR (stroma-low) and high-TSR (stroma-high) groups and enrolled in a training cohort (n = 151) and a validation cohort (n = 68). The least absolute shrinkage and selection operator regression algorithm was used to screen the most optimal clinical, US, and HA features. The selected features were entered into multivariable logistic regression analyses for further selection of independent predictors. Different models, including the nomogram model, the clinic-US (Clin + US) model, and the HA model, were built based on independent predictors using logistic regression. The performance levels of the models were evaluated and validated on the training and validation cohorts.

Results: Lesion size, shape, cystic areas, vascularity, HA_mean, and HA_skewness were identified as independent predictors for constructing the nomogram model. The nomogram model incorporating the clinical, US, and HA features achieved areas under the curve of 0.839 and 0.852 in the training and validation cohorts, respectively, demonstrating good predictive performance and calibration. Decision curve analysis and clinical impact curves further confirmed its clinical usefulness.

Conclusions: The nomogram model we developed offers a practical tool for preoperative TSR prediction in PA, potentially enhancing clinical decision-making.

目的:术前识别唾液腺多形性腺瘤(PA)的不同基质亚型对于治疗决策至关重要。我们旨在开发并验证一种基于超声(US)图像直方图分析(HA)的模型,用于预测涎腺多形性腺瘤的肿瘤间质比率(TSR):将219名PA患者分为低TSR组(基质低)和高TSR组(基质高),并分别纳入训练队列(n = 151)和验证队列(n = 68)。采用最小绝对收缩和选择算子回归算法筛选出最理想的临床、US 和 HA 特征。所选特征被输入多变量逻辑回归分析,以进一步选择独立预测因子。根据独立预测因子,利用逻辑回归建立了不同的模型,包括提名图模型、临床-US(Clinic + US)模型和 HA 模型。在训练组和验证组中对模型的性能水平进行了评估和验证:结果:病变大小、形状、囊性区域、血管、HA_mean 和 HA_skewness 被确定为构建提名图模型的独立预测因素。包含临床、US 和 HA 特征的提名图模型在训练组和验证组中的 AUC 分别为 0.839 和 0.852,显示出良好的预测性能和校准性。决策曲线分析和临床影响曲线进一步证实了该模型的临床实用性:我们开发的提名图模型为 PA 术前 TSR 预测提供了一种实用工具,有望提高临床决策水平。
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引用次数: 0
Improving resolution of panoramic radiographs: super-resolution concept. 提高全景 X 光片的分辨率:超分辨率概念
IF 3.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-04-29 DOI: 10.1093/dmfr/twae009
Mahmut Emin Çelik, Mahsa Mikaeili, Berrin Çelik

Objectives: Dental imaging plays a key role in the diagnosis and treatment of dental conditions, yet limitations regarding the quality and resolution of dental radiographs sometimes hinder precise analysis. Super-resolution with deep learning refers to a set of techniques used to enhance the resolution of images beyond their original size or quality using deep neural networks instead of traditional image interpolation methods which often result in blurred or pixelated images when attempting to increase resolution. Leveraging advancements in technology, this study aims to enhance the resolution of dental panoramic radiographs, thereby enabling more accurate diagnoses and treatment planning.

Methods: About 1714 panoramic radiographs from 3 different open datasets are used for training (n = 1364) and testing (n = 350). The state of the art 4 different models is explored, namely Super-Resolution Convolutional Neural Network (SRCNN), Efficient Sub-Pixel Convolutional Neural Network, Super-Resolution Generative Adversarial Network, and Autoencoder. Performances in reconstructing high-resolution dental images from low-resolution inputs with different scales (s = 2, 4, 8) are evaluated by 2 well-accepted metrics Structural Similarity Index (SSIM) and Peak Signal-to-Noise Ratio (PSNR).

Results: SSIM spans between 0.82 and 0.98 while PSNR are between 28.7 and 40.2 among all scales and models. SRCNN provides the best performance. Additionally, it is observed that performance decreased when images are scaled with higher values.

Conclusion: The findings highlight the potential of super-resolution concepts to significantly improve the quality and detail of dental panoramic radiographs, thereby contributing to enhanced interpretability.

目的:牙科成像在牙科疾病的诊断和治疗中起着关键作用,但牙科射线照片的质量和分辨率的限制有时会妨碍精确分析。深度学习超分辨率是指使用深度神经网络而不是传统的图像插值方法来提高图像分辨率的一套技术,传统的图像插值方法在试图提高分辨率时往往会导致图像模糊或像素化。本研究旨在利用先进的技术提高牙科全景X光片的分辨率,从而实现更准确的诊断和治疗规划:方法:来自 3 个不同开放数据集的约 1714 张全景照片被用于训练(n = 1364)和测试(n = 350)。探索了 4 种不同模型的技术水平,即超分辨率卷积神经网络(SRCNN)、高效子像素卷积神经网络、超分辨率生成对抗网络和自动编码器。通过结构相似性指数(SSIM)和峰值信噪比(PSNR)这两个公认的指标,评估了从不同尺度(s = 2、4、8)的低分辨率输入重建高分辨率牙科图像的性能:在所有尺度和模型中,SSIM 介于 0.82 和 0.98 之间,而 PSNR 介于 28.7 和 40.2 之间。SRCNN 的性能最佳。此外,还观察到当图像的比例值越高时,性能越低:研究结果凸显了超分辨率概念在显著改善牙科全景 X 光照片的质量和细节方面的潜力,从而有助于提高可解释性。
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引用次数: 0
Artificial intelligence system for automatic maxillary sinus segmentation on cone beam computed tomography images. 在锥形束计算机断层扫描图像上自动分割上颌窦的人工智能系统。
IF 3.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-04-29 DOI: 10.1093/dmfr/twae012
Ibrahim Sevki Bayrakdar, Nermin Sameh Elfayome, Reham Ashraf Hussien, Ibrahim Tevfik Gulsen, Alican Kuran, Ihsan Gunes, Alwaleed Al-Badr, Ozer Celik, Kaan Orhan

Objectives: The study aims to develop an artificial intelligence (AI) model based on nnU-Net v2 for automatic maxillary sinus (MS) segmentation in cone beam computed tomography (CBCT) volumes and to evaluate the performance of this model.

Methods: In 101 CBCT scans, MS were annotated using the CranioCatch labelling software (Eskisehir, Turkey) The dataset was divided into 3 parts: 80 CBCT scans for training the model, 11 CBCT scans for model validation, and 10 CBCT scans for testing the model. The model training was conducted using the nnU-Net v2 deep learning model with a learning rate of 0.00001 for 1000 epochs. The performance of the model to automatically segment the MS on CBCT scans was assessed by several parameters, including F1-score, accuracy, sensitivity, precision, area under curve (AUC), Dice coefficient (DC), 95% Hausdorff distance (95% HD), and Intersection over Union (IoU) values.

Results: F1-score, accuracy, sensitivity, precision values were found to be 0.96, 0.99, 0.96, 0.96, respectively for the successful segmentation of maxillary sinus in CBCT images. AUC, DC, 95% HD, IoU values were 0.97, 0.96, 1.19, 0.93, respectively.

Conclusions: Models based on nnU-Net v2 demonstrate the ability to segment the MS autonomously and accurately in CBCT images.

研究目的本研究旨在开发一种基于 nnU-Net v2 的人工智能(AI)模型,用于在锥形束计算机断层扫描(CBCT)图像中自动分割上颌窦(MS),并评估该模型的性能:数据集分为三部分:80 个 CBCT 扫描用于训练模型,11 个 CBCT 扫描用于验证模型,10 个 CBCT 扫描用于测试模型。模型训练使用 nnU-Net v2 深度学习模型,学习率为 0.00001,持续 1000 次。该模型在 CBCT 扫描中自动分割 MS 的性能通过多个参数进行评估,包括 F1 分数、准确率、灵敏度、精确度、曲线下面积(AUC)、骰子系数(DC)、95% Hausdorff 距离(95% HD)和联合交叉(IoU)值:在 CBCT 图像中成功分割上颌窦的 F1 分数、准确度、灵敏度和精确度值分别为 0.96、0.99、0.96 和 0.96。AUC、DC、95% HD、IoU 值分别为 0.97、0.96、1.19、0.93:基于 nnU-Net v2 的模型展示了在 CBCT 图像中自主、准确地分割上颌窦的能力。
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引用次数: 0
Accuracy of linear measurements for implant planning based on low-dose cone beam CT protocols: a systematic review and meta-analysis. 基于低剂量锥形束 CT 方案的种植规划线性测量的准确性:系统综述和荟萃分析低剂量 CBCT 的准确性:系统综述和荟萃分析。
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-04-29 DOI: 10.1093/dmfr/twae007
Ana Luiza E Carneiro, Isabella N R Reis, Fernando Valentim Bitencourt, Daniela M R A Salgado, Claudio Costa, Rubens Spin-Neto

Objectives: The aim of this systematic review was to verify the accuracy of linear measurements performed on low-dose CBCT protocols for implant planning, in comparison with those performed on standard and high-resolution CBCT protocols.

Methods: The literature search included four databases (Pubmed, Web of Science, Embase, and Scopus). Two reviewers independently screened titles/abstracts and full texts according to eligibility criteria, extracted the data, and examined the methodological quality. Risk of bias assessment was performed using the Quality Assessment Tool For In Vitro Studies. Random-effects meta-analysis was used for pooling measurement error data.

Results: The initial search yielded 4684 titles. In total, 13 studies were included in the systematic review, representing a total of 81 samples, while 9 studies were included in the meta-analysis. The risk of bias ranged from medium to low. The main results across the studies indicate a strong consistency in linear measurements performed on low-dose images in relation to the reference methods. The overall pooled planning measurement error from low-dose CBCT protocols was -0.24 mm (95% CI, -0.52 to 0.04) with a high level of heterogeneity, showing a tendency for underestimation of real values. Various studies found no significant differences in measurements across different protocols (eg, voxel sizes, mA settings, or dose levels), regions (incisor, premolar, molar) and types (height vs. width). Some studies, however, noted exceptions in measurements performed on the posterior mandible.

Conclusion: Low-dose CBCT protocols offer adequate precision and accuracy of linear measurements for implant planning. Nevertheless, diagnostic image quality needs must be taken into consideration when choosing a low-dose CBCT protocol.

目的本系统综述的目的是验证低剂量 CBCT 方案与标准和高分辨率 CBCT 方案相比,在种植规划中进行的线性测量的准确性:文献检索包括四个数据库(Pubmed、Web of Science、Embase 和 Scopus)。两名审稿人根据资格标准独立筛选标题/摘要和全文,提取数据并检查方法学质量。采用体外研究质量评估工具对偏倚风险进行评估。随机效应荟萃分析用于汇总测量误差数据:最初的检索共获得 4,684 个标题。共有 13 项研究被纳入系统综述,代表了 81 个样本,9 项研究被纳入荟萃分析。偏倚风险从中度到低度不等。各项研究的主要结果表明,与参考方法相比,在低剂量图像上进行的线性测量具有很强的一致性。低剂量 CBCT 方案的总体规划测量误差为-0.24 毫米(95% CI,-0.52 至 0.04),异质性较高,显示出低估实际值的趋势。多项研究发现,不同方案(如体素大小、毫安设置或剂量水平)、不同区域(门牙、前臼齿、臼齿)和不同类型(高度与宽度)的测量结果无明显差异。然而,一些研究指出,在下颌后部进行的测量存在例外:结论:低剂量 CBCT 方案为种植规划提供了足够的线性测量精度和准确性。然而,在选择低剂量 CBCT 方案时,必须考虑诊断图像质量的需求。
{"title":"Accuracy of linear measurements for implant planning based on low-dose cone beam CT protocols: a systematic review and meta-analysis.","authors":"Ana Luiza E Carneiro, Isabella N R Reis, Fernando Valentim Bitencourt, Daniela M R A Salgado, Claudio Costa, Rubens Spin-Neto","doi":"10.1093/dmfr/twae007","DOIUrl":"10.1093/dmfr/twae007","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this systematic review was to verify the accuracy of linear measurements performed on low-dose CBCT protocols for implant planning, in comparison with those performed on standard and high-resolution CBCT protocols.</p><p><strong>Methods: </strong>The literature search included four databases (Pubmed, Web of Science, Embase, and Scopus). Two reviewers independently screened titles/abstracts and full texts according to eligibility criteria, extracted the data, and examined the methodological quality. Risk of bias assessment was performed using the Quality Assessment Tool For In Vitro Studies. Random-effects meta-analysis was used for pooling measurement error data.</p><p><strong>Results: </strong>The initial search yielded 4684 titles. In total, 13 studies were included in the systematic review, representing a total of 81 samples, while 9 studies were included in the meta-analysis. The risk of bias ranged from medium to low. The main results across the studies indicate a strong consistency in linear measurements performed on low-dose images in relation to the reference methods. The overall pooled planning measurement error from low-dose CBCT protocols was -0.24 mm (95% CI, -0.52 to 0.04) with a high level of heterogeneity, showing a tendency for underestimation of real values. Various studies found no significant differences in measurements across different protocols (eg, voxel sizes, mA settings, or dose levels), regions (incisor, premolar, molar) and types (height vs. width). Some studies, however, noted exceptions in measurements performed on the posterior mandible.</p><p><strong>Conclusion: </strong>Low-dose CBCT protocols offer adequate precision and accuracy of linear measurements for implant planning. Nevertheless, diagnostic image quality needs must be taken into consideration when choosing a low-dose CBCT protocol.</p>","PeriodicalId":11261,"journal":{"name":"Dento maxillo facial radiology","volume":" ","pages":"207-221"},"PeriodicalIF":2.9,"publicationDate":"2024-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11056743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140012373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial intelligence-based automated preprocessing and classification of impacted maxillary canines in panoramic radiographs. 基于人工智能的全景 X 光片上颌犬齿撞击自动预处理和分类。
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-03-25 DOI: 10.1093/dmfr/twae005
Ali Abdulkreem, Tanmoy Bhattacharjee, Hessa Alzaabi, Kawther Alali, Angela Gonzalez, Jahanzeb Chaudhry, Sabarinath Prasad

Objectives: Automating the digital workflow for diagnosing impacted canines using panoramic radiographs (PRs) is challenging. This study explored feature extraction, automated cropping, and classification of impacted and nonimpacted canines as a first step.

Methods: A convolutional neural network with SqueezeNet architecture was first trained to classify two groups of PRs (91with and 91without impacted canines) on the MATLAB programming platform. Based on results, the need to crop the PRs was realized. Next, artificial intelligence (AI) detectors were trained to identify specific landmarks (maxillary central incisors, lateral incisors, canines, bicuspids, nasal area, and the mandibular ramus) on the PRs. Landmarks were then explored to guide cropping of the PRs. Finally, improvements in classification of automatically cropped PRs were studied.

Results: Without cropping, the area under the curve (AUC) of the receiver operating characteristic (ROC) curve for classifying impacted and nonimpacted canine was 84%. Landmark training showed that detectors could correctly identify upper central incisors and the ramus in ∼98% of PRs. The combined use of the mandibular ramus and maxillary central incisors as guides for cropping yielded the best results (∼10% incorrect cropping). When automatically cropped PRs were used, the AUC-ROC improved to 96%.

Conclusions: AI algorithms can be automated to preprocess PRs and improve the identification of impacted canines.

目的:使用全景 X 光片 (PR) 诊断撞击性犬齿的数字化工作流程自动化具有挑战性。本研究首先探索了特征提取、自动裁剪以及受影响和未受影响犬齿的分类:方法:首先在 MATLAB 编程平台上训练采用 SqueezeNet 架构的卷积神经网络 (CNN),对两组 PR(91 个有和 91 个无受影响犬齿)进行分类。根据结果,实现了对 PR 的裁剪。接下来,对人工智能 (AI) 检测器进行了训练,以识别 PR 上的特定地标(上颌中切牙、侧切牙、犬齿、双尖牙、鼻区和下颌横突)。然后对地标进行探索,以指导 PR 的裁剪。最后,研究了自动裁剪 PR 分类的改进情况:结果:在不进行裁剪的情况下,对受撞击和未受撞击犬齿进行分类的接收者工作特征曲线(ROC)下面积为 84%。地标训练显示,检测器可以在98%的PR中正确识别上中切牙和嵴。联合使用下颌横突和上颌中切牙作为裁剪指南的结果最好(错误裁剪率为 10%)。当使用自动裁剪的 PR 时,AUC-ROC 提高到 96%:结论:人工智能算法可以自动对PR进行预处理,并提高对受影响犬齿的识别率。
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引用次数: 0
Panoramic imaging errors in machine learning model development: a systematic review. 机器学习模型开发中的全景成像误差:系统综述。
IF 2.9 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-03-25 DOI: 10.1093/dmfr/twae002
Eduardo Delamare, Xingyue Fu, Zimo Huang, Jinman Kim

Objectives: To investigate the management of imaging errors from panoramic radiography (PAN) datasets used in the development of machine learning (ML) models.

Methods: This systematic literature followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses and used three databases. Keywords were selected from relevant literature.

Eligibility criteria: PAN studies that used ML models and mentioned image quality concerns.

Results: Out of 400 articles, 41 papers satisfied the inclusion criteria. All the studies used ML models, with 35 papers using deep learning (DL) models. PAN quality assessment was approached in 3 ways: acknowledgement and acceptance of imaging errors in the ML model, removal of low-quality radiographs from the dataset before building the model, and application of image enhancement methods prior to model development. The criteria for determining PAN image quality varied widely across studies and were prone to bias.

Conclusions: This study revealed significant inconsistencies in the management of PAN imaging errors in ML research. However, most studies agree that such errors are detrimental when building ML models. More research is needed to understand the impact of low-quality inputs on model performance. Prospective studies may streamline image quality assessment by leveraging DL models, which excel at pattern recognition tasks.

目的研究用于开发机器学习(ML)模型的全景放射摄影(PAN)数据集的成像错误管理:该系统文献遵循《系统综述和元分析首选报告项目》,并使用了三个数据库。从相关文献中选取关键词:使用 ML 模型并提及图像质量问题的 PAN 研究:在 400 篇文章中,有 41 篇符合纳入标准。所有研究都使用了 ML 模型,其中 35 篇论文使用了深度学习 (DL) 模型。PAN 质量评估有三种方法:承认并接受 ML 模型中的成像错误;在建立模型前从数据集中删除低质量的放射照片;在模型开发前应用图像增强方法。不同研究对 PAN 图像质量的判定标准差异很大,而且容易产生偏差:本研究揭示了 ML 研究中对 PAN 成像误差管理的严重不一致。然而,大多数研究都认为,在建立 ML 模型时,这种误差是有害的。需要开展更多研究,以了解低质量输入对模型性能的影响。前瞻性研究可以利用擅长模式识别任务的 DL 模型来简化图像质量评估。
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引用次数: 0
Feasibility of frozen soft tissues to simulate fresh soft tissue conditions in cone beam CT scans. 在锥形束计算机断层扫描(cbct)中使用冷冻软组织模拟新鲜软组织条件的可行性。
IF 3.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-03-25 DOI: 10.1093/dmfr/twae004
Matheus L Oliveira, Michael M Bornstein, Dorothea Dagassan-Berndt

Objectives: To evaluate the feasibility of frozen soft tissues in simulating fresh soft tissues of pig mandibles using cone beam CT (CBCT).

Methods: Two fresh pig mandibles with soft tissues containing 2 tubes filled with a radiopaque homogeneous solution were scanned using 4 CBCT units and 2 field-of-view (FOV) sizes each. The pig mandibles were deep-frozen and scanned again. Three cross-sections were exported from each CBCT volume and grouped into pairs, with one cross-section representing a fresh and one a frozen mandible. Three radiologists compared the pairs and attributed a score to assess the relative image quality using a 5-point scale. Mean grey values and standard deviation were obtained from homogeneous areas in the tubes, compared using the Wilcoxon matched-pair signed-rank test and subjected to Pearson correlation analysis between fresh and frozen physical states (α = .05).

Results: Subjective evaluation revealed similarity of the CBCT image quality between fresh and frozen states. The distribution of mean grey values was similar between fresh and frozen states. Mean grey values of the frozen state in the small FOV were significantly greater than those of the fresh state (P = .037), and noise values of the frozen state in the large FOV were significantly greater than those of the fresh state (P = 0.007). Both mean grey values and noise exhibited significant and positive correlations between fresh and frozen states (P < 0.01).

Conclusions: The freezing of pig mandibles with soft tissues may serve as a method to prolong their usability and working time when CBCT imaging is planned.

目的方法:使用锥形束计算机断层扫描(CBCT)评估冷冻软组织模拟猪下颌骨新鲜软组织的可行性:方法:使用四台 CBCT 设备和两种视场尺寸对两只新鲜猪下颌骨软组织进行扫描,其中包含两支装有不透射线均质溶液的管子。猪下颌骨被深冻后再次扫描。从每个 CBCT 容积中导出三个横截面,并将其组合成对,其中一个横截面代表新鲜下颌骨,另一个代表冷冻下颌骨。三位放射科医生对这两对横截面进行比较,并用 5 分制评分来评估相对图像质量。从管中的同质区域获得平均灰度值和标准偏差,使用 Wilcoxon 配对符号秩检验进行比较,并对新鲜和冷冻物理状态进行皮尔逊相关分析(α = 0.05):主观评价显示,新鲜和冷冻状态下的 CBCT 图像质量相似。新鲜和冷冻状态的平均灰度值分布相似。冷冻状态在小 FOV 下的平均灰度值明显高于新鲜状态(p = 0.037),冷冻状态在大 FOV 下的噪声值明显高于新鲜状态(p = 0.007)。平均灰度值和噪声在新鲜状态和冷冻状态之间均表现出显著的正相关性(p 结论:冷冻状态的平均灰度值和噪声在新鲜状态和冷冻状态之间均表现出显著的正相关性:在计划进行 CBCT 成像时,冷冻猪下颌骨软组织可作为延长其可用性和工作时间的一种方法。
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引用次数: 0
The use of CBCT in orthodontics with special focus on upper airway analysis in patients with sleep-disordered breathing. CBCT 在正畸学中的应用,特别关注睡眠呼吸障碍患者的上气道分析。
IF 3.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-03-25 DOI: 10.1093/dmfr/twae001
Fabio Savoldi, Dorothea Dagassan-Berndt, Raphael Patcas, Wing-Sze Mak, Georgios Kanavakis, Carlalberta Verna, Min Gu, Michael M Bornstein

Applications of cone-beam CT (CBCT) in orthodontics have been increasingly discussed and evaluated in science and practice over the last two decades. The present work provides a comprehensive summary of current consolidated practice guidelines, cutting-edge innovative applications, and future outlooks about potential use of CBCT in orthodontics with a special focus on upper airway analysis in patients with sleep-disordered breathing. The present scoping review reveals that clinical applications of CBCT in orthodontics are broadly supported by evidence for the diagnosis of dental anomalies, temporomandibular joint disorders, and craniofacial malformations. On the other hand, CBCT imaging for upper airway analysis-including soft tissue diagnosis and airway morphology-needs further validation in order to provide better understanding regarding which diagnostic questions it can be expected to answer. Internationally recognized guidelines for CBCT use in orthodontics are existent, and similar ones should be developed to provide clear indications about the appropriate use of CBCT for upper airway assessment, including a list of specific clinical questions justifying its prescription.

在过去的二十年里,锥束计算机断层扫描(CBCT)在口腔正畸学中的应用在科学和实践中得到了越来越多的讨论和评估。本研究全面总结了当前的综合实践指南、最前沿的创新应用以及 CBCT 在正畸学中潜在应用的未来展望,并特别关注睡眠呼吸障碍(SDB)患者的上气道分析。本范围综述显示,CBCT 在口腔正畸学中的临床应用在诊断牙齿畸形、颞下颌关节紊乱和颅面畸形方面得到了广泛的证据支持。另一方面,用于上气道分析的 CBCT 成像--包括软组织诊断和气道形态学--需要进一步验证,以便更好地了解它可以回答哪些诊断问题。目前已有国际公认的 CBCT 在正畸学中的应用指南,应制定类似的指南,明确说明 CBCT 在上气道评估中的适当应用,包括证明其合理性的具体临床问题列表。
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引用次数: 0
Clinical and radiological features of malformed mesiodens in the nasopalatine canal: an observational study. 鼻腭管畸形中碘的临床和放射学特征:一项观察性研究。
IF 3.3 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-03-25 DOI: 10.1093/dmfr/twae003
Yu-Ri Kim, Yu-Min Lee, Kyung-Hoe Huh, Won-Jin Yi, Min-Suk Heo, Sam-Sun Lee, Jo-Eun Kim

Objectives: The purpose of this study is to investigate the morphological changes that occur when mesiodens is located within the nasopalatine canal, as well as clinical characteristics.

Methods: Clinical records and CT images of patients who had mesiodens in the nasopalatine canal were retrospectively analysed. In addition to demographic information, clinical symptoms and complications associated with extraction of mesiodens were recorded. Using CT images, number, location, size, and tooth morphology were evaluated.

Results: This study included 32 patients and 38 mesiodens within the nasopalatine canal. Supernumerary teeth exhibited a characteristic feature of thin and elongated shape in the canal (narrow width and elongation were observed in 96.6% and 53.3% of the patients, respectively). Fusion was found in 4 patients and dilaceration in 12. A complication occurred in 2 patients, which was tooth remnant, not a neurologic complication. Only 5 mesiodens could be detected in the nasopalatine canal on panoramic images.

Conclusions: Morphological abnormalities in mesiodens within the nasopalatine canal were frequently detected, and these could be effectively diagnosed through 3D imaging analysis.

研究目的本研究的目的是探究鼻腭管内中碘的形态变化以及临床特征:方法:回顾性分析鼻腭管内中碘患者的临床记录和计算机断层扫描(CT)图像。除人口统计学信息外,还记录了与拔除间碘相关的临床症状和并发症。通过 CT 图像,对中碘的数量、位置、大小和牙齿形态进行了评估:这项研究包括 32 名患者和 38 个鼻腭管内的间碘。超常牙齿在鼻腭管内呈现出细长形状的特征(分别有 96.6% 和 53.3% 的患者观察到窄宽和细长)。有 4 名患者的牙槽骨融合,12 名患者的牙槽骨扩张。两名患者出现了并发症,是牙齿残留,而不是神经系统并发症。在全景图像上,鼻腭管内只发现了五个间碘:结论:鼻腭管内的间碘形态异常经常被发现,通过三维成像分析可有效诊断这些异常。
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Dento maxillo facial radiology
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