Mihaela Păstrav, Radu Marcel Chisnoiu, Marioara Moldovan, Lucian Barbu Tudoran, Ioan Petean, Andrea Maria Chisnoiu, Ovidiu Păstrav
Objectives: This study evaluated and compared the sealing ability and elemental composition of a resin-based endodontic sealer (AH Plus) used with three root canal obturation techniques: single cone (SC), lateral compaction (LC), and warm vertical condensation (WVC). The investigation focused on microstructural characteristics, interfacial integrity, and elemental distribution within filled root canals. Material and Methods: Sixty extracted single-root teeth were instrumented using the ProTaper Gold system and randomly assigned to three groups (n = 20) according to the obturation technique. The AH Plus Jet sealer was applied in all cases. Following obturation, samples were subjected to radiographic investigation and analyzed using optical microscopy and scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy (EDX) to assess the sealing performance and chemical composition. Results: Radiographic and microscopic assessments indicated that the SC method showed strong gutta-percha adhesion to dentin with a thin cement layer, whereas WVC provided excellent adaptation and penetration of gutta-percha. The LC technique demonstrated good adhesion but displayed occasional structural irregularities. SC has the thicker adhesion layer with uneven distribution regarding coronal, median, and apical, regions ranging from 45 to 80 μm, while WVC ensures a thin and uniform sealing layer of about 35 μm in all regions. SEM and EDX analyses detailed the interfacial microstructure and confirmed the presence of carbon (C), oxygen (O), calcium (Ca), zinc (Zn), barium (Ba), and sulfur (S) across all groups. Conclusions: All three obturation techniques (SC, WVC, LC) achieved effective sealing when combined with the AH Plus sealer. The main difference between the methods consists of the sealer layer thickness and its even distribution regarding gutta-percha cones.
{"title":"Advanced Microstructural Investigation of the Endodontic Sealing Ability of Three Different Obturation Techniques.","authors":"Mihaela Păstrav, Radu Marcel Chisnoiu, Marioara Moldovan, Lucian Barbu Tudoran, Ioan Petean, Andrea Maria Chisnoiu, Ovidiu Păstrav","doi":"10.3390/dj14010009","DOIUrl":"https://doi.org/10.3390/dj14010009","url":null,"abstract":"<p><p><b>Objectives:</b> This study evaluated and compared the sealing ability and elemental composition of a resin-based endodontic sealer (AH Plus) used with three root canal obturation techniques: single cone (SC), lateral compaction (LC), and warm vertical condensation (WVC). The investigation focused on microstructural characteristics, interfacial integrity, and elemental distribution within filled root canals. <b>Material and Methods:</b> Sixty extracted single-root teeth were instrumented using the ProTaper Gold system and randomly assigned to three groups (<i>n</i> = 20) according to the obturation technique. The AH Plus Jet sealer was applied in all cases. Following obturation, samples were subjected to radiographic investigation and analyzed using optical microscopy and scanning electron microscopy (SEM) coupled with energy-dispersive X-ray spectroscopy (EDX) to assess the sealing performance and chemical composition. <b>Results:</b> Radiographic and microscopic assessments indicated that the SC method showed strong gutta-percha adhesion to dentin with a thin cement layer, whereas WVC provided excellent adaptation and penetration of gutta-percha. The LC technique demonstrated good adhesion but displayed occasional structural irregularities. SC has the thicker adhesion layer with uneven distribution regarding coronal, median, and apical, regions ranging from 45 to 80 μm, while WVC ensures a thin and uniform sealing layer of about 35 μm in all regions. SEM and EDX analyses detailed the interfacial microstructure and confirmed the presence of carbon (C), oxygen (O), calcium (Ca), zinc (Zn), barium (Ba), and sulfur (S) across all groups. <b>Conclusions:</b> All three obturation techniques (SC, WVC, LC) achieved effective sealing when combined with the AH Plus sealer. The main difference between the methods consists of the sealer layer thickness and its even distribution regarding gutta-percha cones.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"14 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Smoking has a detrimental effect on the periodontal condition. Smoking intensity has recently been considered as a criterion for grading periodontitis cases. However, the influence of smoking intensity on the subgingival microbial community has not been evaluated in depth. This cross-sectional analytical study aims to assess the differences in the subgingival microbiome in adult patients with chronic periodontitis and different smoking habits (heavy smokers versus moderate smokers versus non-smokers). Methods: Sixty patients diagnosed with chronic periodontitis were grouped according to their daily smoking intensity as follows: group I (smoke ≥ 10 cigarettes/day), group II (smoke < 10 cigarettes/day), and non-smokers (group III). For each patient, samples from subgingival plaque were harvested from the deepest three periodontal pockets, and their 16S rRNA was sequenced using the S5 Ion Torrent platform. Sequences were clustered in taxonomic units, and the microbial diversity was expressed using the Shannon index or Simpson index, while the abundance of the microbial species was expressed using the Chao index. Results: Bacterial diversity was lowest in the heavy smoker group (group I) and highest in non-smokers (group III). Veillonella, Streptococcus, Prevotella, Fusobacterium, and Dialister were found to have different prevalences in the three study groups. Campylobacter decreased and Fusobacterium increased as a function of the number of cigarettes smoked per day. The moderate smoker group showed a higher abundance of Spirochaetes. At the species level, the heavy smoker group (group I) showed a higher abundance of Fusobacterium compared to the other two groups. Conclusions: Greater smoking intensity has been associated with higher Fusobacterium abundance, together with decreased diversity of the subgingival microbiome, establishing a more stable putative subgingival bacterial environment.
背景:吸烟对牙周状况有不利影响。吸烟强度最近被认为是牙周炎病例分级的标准。然而,吸烟强度对牙龈下微生物群落的影响尚未得到深入的评价。本横断面分析研究旨在评估慢性牙周炎成年患者和不同吸烟习惯(重度吸烟者、中度吸烟者和非吸烟者)龈下微生物组的差异。方法:将60例慢性牙周炎患者按每日吸烟强度分为三组:ⅰ组(吸烟≥10支/d)、ⅱ组(吸烟< 10支/d)和非吸烟者(III组)。对于每位患者,从最深的三个牙周袋中收集牙龈下菌斑样本,并使用S5 Ion Torrent平台对其16S rRNA进行测序。序列按分类单位聚类,微生物多样性用Shannon指数或Simpson指数表示,微生物种类丰度用Chao指数表示。结果:重度吸烟者组(ⅰ组)细菌多样性最低,非吸烟者组(ⅲ组)细菌多样性最高。细孔菌、链球菌、普雷沃氏菌、梭杆菌和Dialister在三个研究组中有不同的患病率。弯曲杆菌减少,梭杆菌增加,这是每天吸烟数量的函数。适度吸烟组显示出更高的螺旋体丰度。在物种水平上,重度吸烟者组(I组)的梭杆菌丰度高于其他两组。结论:吸烟强度越大,梭杆菌的丰度越高,牙龈下微生物群的多样性越低,从而建立了一个更稳定的牙龈下细菌环境。
{"title":"Effect of Smoking on Subgingival Microbiome in Chronic Periodontitis: A 16S rRNA Sequencing Study.","authors":"Jazia A Alblowi","doi":"10.3390/dj14010010","DOIUrl":"https://doi.org/10.3390/dj14010010","url":null,"abstract":"<p><p><b>Background</b>: Smoking has a detrimental effect on the periodontal condition. Smoking intensity has recently been considered as a criterion for grading periodontitis cases. However, the influence of smoking intensity on the subgingival microbial community has not been evaluated in depth. This cross-sectional analytical study aims to assess the differences in the subgingival microbiome in adult patients with chronic periodontitis and different smoking habits (heavy smokers versus moderate smokers versus non-smokers). <b>Methods</b>: Sixty patients diagnosed with chronic periodontitis were grouped according to their daily smoking intensity as follows: group I (smoke ≥ 10 cigarettes/day), group II (smoke < 10 cigarettes/day), and non-smokers (group III). For each patient, samples from subgingival plaque were harvested from the deepest three periodontal pockets, and their 16S rRNA was sequenced using the S5 Ion Torrent platform. Sequences were clustered in taxonomic units, and the microbial diversity was expressed using the Shannon index or Simpson index, while the abundance of the microbial species was expressed using the Chao index. <b>Results</b>: Bacterial diversity was lowest in the heavy smoker group (group I) and highest in non-smokers (group III). <i>Veillonella</i>, <i>Streptococcus</i>, <i>Prevotella</i>, <i>Fusobacterium</i>, and <i>Dialister</i> were found to have different prevalences in the three study groups. <i>Campylobacter</i> decreased and <i>Fusobacterium</i> increased as a function of the number of cigarettes smoked per day. The moderate smoker group showed a higher abundance of <i>Spirochaetes.</i> At the species level, the heavy smoker group (group I) showed a higher abundance of <i>Fusobacterium</i> compared to the other two groups. <b>Conclusions</b>: Greater smoking intensity has been associated with higher <i>Fusobacterium</i> abundance, together with decreased diversity of the subgingival microbiome, establishing a more stable putative subgingival bacterial environment.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"14 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kinga Wnorowska, Katarzyna Dębkowska, Zuzanna Borawska, Stefanie Samietz, Joanna Bagińska, Inga Kamińska, Marlena Dubatówka, Zofia Stachurska, Paweł Sowa, Karol A Kamiński, Magdalena Nowosielska
Background/Objectives: Tooth loss is a key marker of ageing and is linked to functional, psychological, and nutritional decline. Removable dental prostheses (RDPs) are widely used, yet their impact on life satisfaction and oral health-related quality of life (OHRQoL) remains uncertain. This study aimed to: (1) identify dental deficiencies in adults aged ≥50 years; (2) assess the use of RDPs; and (3) examine the relationship between prosthetic status, life satisfaction, and OHRQoL. Methods: This retrospective cross-sectional analysis included 986 participants from the Białystok PLUS cohort (2018-2024). Dental examinations classified individuals into: Group 0 (no deficiencies), Group 1 (deficiencies without prostheses), and Group 2 (deficiencies with RDPs). Life satisfaction was measured using the Satisfaction with Life Scale (SWLS), and OHRQoL using the Geriatric Oral Health Assessment Index (GOHAI). Analyses included Kruskal-Wallis test and correspondence analysis. Results: Partial mandibular deficiencies were the most frequent and were less often rehabilitated than maxillary defects. Most prostheses were mucosa-supported. Life satisfaction (mean SWLS = 22.4) did not differ significantly between groups (p = 0.326). In contrast, OHRQoL differed significantly (mean GOHAI = 53.8; p = 0.0001), supporting an effect of prosthetic status. Group 0 showed the highest GOHAI scores (55.7), while Group 2 (52.7) scored lower than Group 1 (53.0). Prosthesis users most often reported dissatisfaction with appearance and eating comfort. Conclusions: Life satisfaction appears independent of prosthetic status. OHRQoL, however, is strongly associated with dentition: individuals without deficiencies report the highest outcomes, whereas RDPs-especially mucosa-supported types-do not improve, and may reduce, perceived OHRQoL.
{"title":"Prosthetic Status, Removable Prostheses and Quality of Life in Older Adults: A Retrospective Cross-Sectional Analysis Within a Population-Based Study.","authors":"Kinga Wnorowska, Katarzyna Dębkowska, Zuzanna Borawska, Stefanie Samietz, Joanna Bagińska, Inga Kamińska, Marlena Dubatówka, Zofia Stachurska, Paweł Sowa, Karol A Kamiński, Magdalena Nowosielska","doi":"10.3390/dj14010007","DOIUrl":"https://doi.org/10.3390/dj14010007","url":null,"abstract":"<p><p><b>Background/Objectives:</b> Tooth loss is a key marker of ageing and is linked to functional, psychological, and nutritional decline. Removable dental prostheses (RDPs) are widely used, yet their impact on life satisfaction and oral health-related quality of life (OHRQoL) remains uncertain. This study aimed to: (1) identify dental deficiencies in adults aged ≥50 years; (2) assess the use of RDPs; and (3) examine the relationship between prosthetic status, life satisfaction, and OHRQoL. <b>Methods:</b> This retrospective cross-sectional analysis included 986 participants from the Białystok PLUS cohort (2018-2024). Dental examinations classified individuals into: Group 0 (no deficiencies), Group 1 (deficiencies without prostheses), and Group 2 (deficiencies with RDPs). Life satisfaction was measured using the Satisfaction with Life Scale (SWLS), and OHRQoL using the Geriatric Oral Health Assessment Index (GOHAI). Analyses included Kruskal-Wallis test and correspondence analysis. <b>Results:</b> Partial mandibular deficiencies were the most frequent and were less often rehabilitated than maxillary defects. Most prostheses were mucosa-supported. Life satisfaction (mean SWLS = 22.4) did not differ significantly between groups (<i>p</i> = 0.326). In contrast, OHRQoL differed significantly (mean GOHAI = 53.8; <i>p</i> = 0.0001), supporting an effect of prosthetic status. Group 0 showed the highest GOHAI scores (55.7), while Group 2 (52.7) scored lower than Group 1 (53.0). Prosthesis users most often reported dissatisfaction with appearance and eating comfort. <b>Conclusions:</b> Life satisfaction appears independent of prosthetic status. OHRQoL, however, is strongly associated with dentition: individuals without deficiencies report the highest outcomes, whereas RDPs-especially mucosa-supported types-do not improve, and may reduce, perceived OHRQoL.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"14 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background/Objectives: The purpose of this study was to assess the in vitro biocompatibility and corrosion resistance of five titanium alloys that have been recently developed for dental implant applications, whose compositions were designed to align with current approaches in the development of novel biomaterials. Priority was given to limiting the harmfulness associated with specific chemical elements present in common conventional alloys and increasing corrosion resistance to improve the biomaterial-tissue cellular interaction. Methods: For this purpose, five types of titanium alloys with original chemical compositions (Ti1-Ti5) were developed. The electrochemical behavior of the alloys was analyzed by evaluating the corrosion resistance in environments that simulate the oral environment, as well as the cellular behavior, by evaluating the viability, growth, and proliferation of human cells on osteoblasts and gingival fibroblasts. Detailed analysis of the chemical composition by scanning electron microscope (SEM/EDS) methods was used. The corrosion rate of the alloys in artificial saliva was tested using the polarization resistance technique (Tafel). Human osteoblasts (hFOB cell line) and human gingival fibroblasts (hFIB-G cell line) were used to measure biocompatibility in vitro. Results: The Ti5 alloy demonstrated the highest cell viability and the lowest corrosion rate (0.114 μm/year) among all tested compositions, with the Ti3 alloy containing Mo and Zr following closely behind. The Ti2 alloy exhibited reduced biocompatibility because of the inclusion of Ni and Fe in its composition. Conclusions: Taken together, the results of this study provide useful information on the basic characteristics of titanium alloys with original chemical compositions. The titanium alloys were analyzed in comparison with common conventional alloys (Cp-Ti and Ti6Al4V) as well as alloys such as Ti-Zr, Ti-Nb, and Ti-Nb-Zr-Ta, which are considered to be viable alternatives to conventional materials for making dental implants.
{"title":"Biocompatibility Evaluation of Novel Experimental Titanium Alloys for Dental Implants.","authors":"Vlad-Gabriel Vasilescu, Lucian Toma Ciocan, Andreea Mihaela Custura, Miruna Stan, Florin Miculescu, Cosmin Mihai Cotrut, Diana Maria Vranceanu, Elisabeta Vasilescu, Marina Imre, Silviu Mirel Pițuru","doi":"10.3390/dj14010006","DOIUrl":"https://doi.org/10.3390/dj14010006","url":null,"abstract":"<p><p><b>Background/Objectives</b>: The purpose of this study was to assess the in vitro biocompatibility and corrosion resistance of five titanium alloys that have been recently developed for dental implant applications, whose compositions were designed to align with current approaches in the development of novel biomaterials. Priority was given to limiting the harmfulness associated with specific chemical elements present in common conventional alloys and increasing corrosion resistance to improve the biomaterial-tissue cellular interaction. <b>Methods</b>: For this purpose, five types of titanium alloys with original chemical compositions (Ti1-Ti5) were developed. The electrochemical behavior of the alloys was analyzed by evaluating the corrosion resistance in environments that simulate the oral environment, as well as the cellular behavior, by evaluating the viability, growth, and proliferation of human cells on osteoblasts and gingival fibroblasts. Detailed analysis of the chemical composition by scanning electron microscope (SEM/EDS) methods was used. The corrosion rate of the alloys in artificial saliva was tested using the polarization resistance technique (Tafel). Human osteoblasts (hFOB cell line) and human gingival fibroblasts (hFIB-G cell line) were used to measure biocompatibility in vitro. <b>Results</b>: The Ti5 alloy demonstrated the highest cell viability and the lowest corrosion rate (0.114 μm/year) among all tested compositions, with the Ti3 alloy containing Mo and Zr following closely behind. The Ti2 alloy exhibited reduced biocompatibility because of the inclusion of Ni and Fe in its composition. <b>Conclusions:</b> Taken together, the results of this study provide useful information on the basic characteristics of titanium alloys with original chemical compositions. The titanium alloys were analyzed in comparison with common conventional alloys (Cp-Ti and Ti6Al4V) as well as alloys such as Ti-Zr, Ti-Nb, and Ti-Nb-Zr-Ta, which are considered to be viable alternatives to conventional materials for making dental implants.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"14 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Aydin, Lawik Revend, Doha Revend, Manfred Giese, Oliver Schuck, Stephanie Roj, Johannes Schunk, Florian Dudde
Background: Facial fractures are common in emergency and trauma care, with age and sex known to influence fracture patterns, injury mechanisms, and treatment approaches. However, detailed comparative data analyzing these demographic variables separately remain limited. Methods: In this retrospective single-center study, we analyzed 561 patients with radiologically confirmed facial fractures who were treated between January 2021 and December 2022. Patients were stratified by sex and age (<50 vs. ≥50 years). Fracture types, trauma causes, and treatment modalities were compared using odds ratios (ORs) with 95% confidence intervals (CIs). Results: Male patients comprised 60.1% of the cohort. Interpersonal violence, alcohol-related trauma, and sports injuries were significantly more frequent in males, while females experienced more falls and syncopes (p < 0.001). Although most fracture types did not differ significantly by sex, female patients underwent surgical treatment significantly less often than males (OR = 0.45, 95% CI: 0.32-0.64, p < 0.001). Patients over 50 years were significantly less likely to suffer mandibular fractures (OR = 0.59, 95% CI: 0.40-0.88, p = 0.009), while frontal sinus fractures were more common in older individuals (OR = 4.77, 95% CI: 1.02-22.27, p = 0.029). Younger patients more often experienced interpersonal violence, alcohol-related incidents, and received operative care, whereas falls and conservative treatment were more frequent among older individuals. Conclusions: Age and sex significantly influence the epidemiology and management of facial fractures. Understanding these demographic differences can guide targeted prevention strategies and assist clinical decision-making in facial trauma care.
背景:面部骨折在急诊和创伤护理中很常见,已知年龄和性别会影响骨折类型、损伤机制和治疗方法。然而,单独分析这些人口统计变量的详细比较数据仍然有限。方法:在这项回顾性单中心研究中,我们分析了561例在2021年1月至2022年12月期间接受放射学证实的面部骨折患者。患者按性别和年龄分层(结果:男性患者占队列的60.1%)。人际暴力、酒精相关创伤和运动损伤在男性中更为常见,而女性则更多地经历跌倒和晕厥(p < 0.001)。尽管大多数骨折类型在性别上没有显著差异,但女性患者接受手术治疗的频率明显低于男性(OR = 0.45, 95% CI: 0.32-0.64, p < 0.001)。50岁以上的患者患下颌骨折的可能性明显降低(OR = 0.59, 95% CI: 0.40-0.88, p = 0.009),而额窦骨折在老年人中更为常见(OR = 4.77, 95% CI: 1.02-22.27, p = 0.029)。年轻患者更常经历人际暴力、酒精相关事件,并接受手术治疗,而老年人更常发生跌倒和保守治疗。结论:年龄和性别对面部骨折的流行病学和治疗有显著影响。了解这些人口统计学差异可以指导有针对性的预防策略,并有助于面部创伤护理的临床决策。
{"title":"Face First: The Role of Age and Sex in the Epidemiology of Facial Fractures.","authors":"Anna Aydin, Lawik Revend, Doha Revend, Manfred Giese, Oliver Schuck, Stephanie Roj, Johannes Schunk, Florian Dudde","doi":"10.3390/dj14010004","DOIUrl":"https://doi.org/10.3390/dj14010004","url":null,"abstract":"<p><p><b>Background:</b> Facial fractures are common in emergency and trauma care, with age and sex known to influence fracture patterns, injury mechanisms, and treatment approaches. However, detailed comparative data analyzing these demographic variables separately remain limited. <b>Methods:</b> In this retrospective single-center study, we analyzed 561 patients with radiologically confirmed facial fractures who were treated between January 2021 and December 2022. Patients were stratified by sex and age (<50 vs. ≥50 years). Fracture types, trauma causes, and treatment modalities were compared using odds ratios (ORs) with 95% confidence intervals (CIs). <b>Results:</b> Male patients comprised 60.1% of the cohort. Interpersonal violence, alcohol-related trauma, and sports injuries were significantly more frequent in males, while females experienced more falls and syncopes (<i>p</i> < 0.001). Although most fracture types did not differ significantly by sex, female patients underwent surgical treatment significantly less often than males (OR = 0.45, 95% CI: 0.32-0.64, <i>p</i> < 0.001). Patients over 50 years were significantly less likely to suffer mandibular fractures (OR = 0.59, 95% CI: 0.40-0.88, <i>p</i> = 0.009), while frontal sinus fractures were more common in older individuals (OR = 4.77, 95% CI: 1.02-22.27, <i>p</i> = 0.029). Younger patients more often experienced interpersonal violence, alcohol-related incidents, and received operative care, whereas falls and conservative treatment were more frequent among older individuals. <b>Conclusions:</b> Age and sex significantly influence the epidemiology and management of facial fractures. Understanding these demographic differences can guide targeted prevention strategies and assist clinical decision-making in facial trauma care.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"14 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eduardo Escaf-Robles, Aritza Brizuela-Velasco, Daniel Robles-Cantero, Saray Fernández-Hernández, Javier Gil, Hector de Llanos-Lanchares
Background/Objectives: There is evidence of possible contamination of prosthetic components originating from dental laboratories. The aim of this study is to investigate the disinfectant effect of citric acid and polyethylene glycol on implant-prosthetic materials in comparison with an untreated control and chlorhexidine. Methods: A total of 720 disks made of three different materials (titanium grade V, zirconia coated with feldspathic ceramic, and PMMA) contaminated with three bacteria (Staphylococcus aureus, Enterococcus faecalis, and porphyromonas gingivalis) were analyzed. Four treatment groups were tested: citric acid, polyethylene glycol, chlorhexidine and an untreated control group. Two assessment periods (3 and 21 days of incubation) were used, with bacterial metabolic activity measured using the resazurin reduction test and then analyzed by electron microscopy. Results: The results show that chlorhexidine has a superior inhibitory effect on all materials and bacterial strains in the short-term evaluation (3 days), while citric acid and polyethylene glycol showed higher efficacy after 21 days. Citric acid also exhibits differential effects when applied to grade V titanium. These differences were statistically significant at p < 0.05. Conclusions: There is evidence to recommend chlorhexidine for the disinfection of laboratory prosthetic components, but the enhanced effect of citric acid on grade V titanium and its long-term efficacy make it clinically promising candidate.
{"title":"Disinfection Strategies for Implant-Related Prosthetic Materials: An In Vitro Evaluation of Citric Acid, Chlorhexidine and Polyethylene Glycol.","authors":"Eduardo Escaf-Robles, Aritza Brizuela-Velasco, Daniel Robles-Cantero, Saray Fernández-Hernández, Javier Gil, Hector de Llanos-Lanchares","doi":"10.3390/dj14010008","DOIUrl":"https://doi.org/10.3390/dj14010008","url":null,"abstract":"<p><p><b>Background/Objectives</b>: There is evidence of possible contamination of prosthetic components originating from dental laboratories. The aim of this study is to investigate the disinfectant effect of citric acid and polyethylene glycol on implant-prosthetic materials in comparison with an untreated control and chlorhexidine. <b>Methods</b>: A total of 720 disks made of three different materials (titanium grade V, zirconia coated with feldspathic ceramic, and PMMA) contaminated with three bacteria (<i>Staphylococcus aureus</i>, <i>Enterococcus faecalis</i>, <i>and porphyromonas gingivalis</i>) were analyzed. Four treatment groups were tested: citric acid, polyethylene glycol, chlorhexidine and an untreated control group. Two assessment periods (3 and 21 days of incubation) were used, with bacterial metabolic activity measured using the resazurin reduction test and then analyzed by electron microscopy. <b>Results</b>: The results show that chlorhexidine has a superior inhibitory effect on all materials and bacterial strains in the short-term evaluation (3 days), while citric acid and polyethylene glycol showed higher efficacy after 21 days. Citric acid also exhibits differential effects when applied to grade V titanium. These differences were statistically significant at <i>p</i> < 0.05. <b>Conclusions</b>: There is evidence to recommend chlorhexidine for the disinfection of laboratory prosthetic components, but the enhanced effect of citric acid on grade V titanium and its long-term efficacy make it clinically promising candidate.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"14 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexandra Cristina Maroiu, Magda Mihaela Luca, Anca Jivanescu
Background/Objectives: Chipping of the veneering part of the crown at the zirconia-porcelain interface remains a major complication of bilayered zirconia systems. This systematic review evaluated whether incorporating a lithium-disilicate (LD) liner or press-on or CAD-on interlayer between zirconia and veneer improves bond strength and fracture performance in vitro. Methods: Following PRISMA 2020, we searched PubMed, Scopus, and Web of Science up to 7 September 2025 for open-access English in vitro studies using LD-based interlayers at zirconia-veneer interfaces and reporting quantitative bond and/or fracture outcomes. Data included extracted materials, processing parameters, and mechanical results; due to heterogeneity, findings were synthesized descriptively and as the ratio-of-means (ROM). Results: Five in vitro studies from Korea, Thailand, and India met the criteria. LD interlayers increased microtensile bond strength from 18.83 to 44.20 MPa and from 19.6 to 47.7 MPa, and shear bond strength from 41.3 to 59.7 MPa, 11.40 ± 1.29 to 18.81 ± 1.76 MPa, and 21.5 to 60.2 MPa. Corresponding ROMs ranged from 1.46 to 2.80 (median 2.35), with thermocycled LD groups maintaining strengths >25 MPa. LD liners also raised crown fracture loads from ~2.18 to ~3.45 kN and characteristic strength from 3.42 to 5.64 kN, while chipping loads in implant crowns increased from ~0.34 to ~0.84 kN and global fracture from ~1.71 to ~1.93 kN. Conclusions: Across diverse zirconia-veneer configurations, LD interlayers consistently enhanced bond metrics and fracture/chipping resistance, supporting their use as a targeted interfacial strategy; however, clinical confirmation is still needed.
{"title":"Effect of Lithium-Disilicate Liners on Bond Strength and Fracture Resistance of Bilayered Zirconia Systems: A Systematic Review of In Vitro Evidence.","authors":"Alexandra Cristina Maroiu, Magda Mihaela Luca, Anca Jivanescu","doi":"10.3390/dj14010005","DOIUrl":"https://doi.org/10.3390/dj14010005","url":null,"abstract":"<p><p><b>Background</b>/<b>Objectives:</b> Chipping of the veneering part of the crown at the zirconia-porcelain interface remains a major complication of bilayered zirconia systems. This systematic review evaluated whether incorporating a lithium-disilicate (LD) liner or press-on or CAD-on interlayer between zirconia and veneer improves bond strength and fracture performance in vitro. <b>Methods:</b> Following PRISMA 2020, we searched PubMed, Scopus, and Web of Science up to 7 September 2025 for open-access English in vitro studies using LD-based interlayers at zirconia-veneer interfaces and reporting quantitative bond and/or fracture outcomes. Data included extracted materials, processing parameters, and mechanical results; due to heterogeneity, findings were synthesized descriptively and as the ratio-of-means (ROM). <b>Results:</b> Five in vitro studies from Korea, Thailand, and India met the criteria. LD interlayers increased microtensile bond strength from 18.83 to 44.20 MPa and from 19.6 to 47.7 MPa, and shear bond strength from 41.3 to 59.7 MPa, 11.40 ± 1.29 to 18.81 ± 1.76 MPa, and 21.5 to 60.2 MPa. Corresponding ROMs ranged from 1.46 to 2.80 (median 2.35), with thermocycled LD groups maintaining strengths >25 MPa. LD liners also raised crown fracture loads from ~2.18 to ~3.45 kN and characteristic strength from 3.42 to 5.64 kN, while chipping loads in implant crowns increased from ~0.34 to ~0.84 kN and global fracture from ~1.71 to ~1.93 kN. <b>Conclusions:</b> Across diverse zirconia-veneer configurations, LD interlayers consistently enhanced bond metrics and fracture/chipping resistance, supporting their use as a targeted interfacial strategy; however, clinical confirmation is still needed.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"14 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maja Žagar, Ines Kovačić, Robert Pongrac, Robert Ćelić
Background/Objectives: Super translucent zirconia (ST zirconia) is increasingly used for esthetic restorations, but its optical stability after mechanical wear remains unclear. This study aimed to evaluate the effects of three finishing protocols-polishing, glazing, and staining followed by glazing (Chroma + Glaze)-on the color stability and translucency of ST zirconia after simulated toothbrushing. Methods: Sixty zirconia specimens (Vita YZ ST, shade A1) were fabricated and divided into three groups, namely Polished, Glazed, and Chroma + Glaze (n = 20 in each group). Color (L*, a*, b*) was measured using a spectrophotometer (VITA Easyshade V; VITA Zahnfabrik) before and after 10,000 brushing cycles (200 g load, 1.5 Hz). Translucency parameters (TPab, TP00) were calculated, while color changes were assessed using CIELAB (ΔEab) and CIEDE2000 (ΔE00) formulas. Data were analyzed using two-way ANOVA and Kruskal-Wallis tests (α = 0.05). Results: Treatment significantly affected translucency (H = 46.79, p < 0.001; H = 21.09, p < 0.001), indicating consistent differences among the three treatment groups. Bonferroni-adjusted post hoc comparisons showed that Chroma + Glaze exhibited significantly lower TP00 values than Glaze in both measurements (p < 0.0001; p < 0.001), as well as lower values than Polished in both measurements (p < 0.0001; p = 0.0147, respectively). Kruskal-Wallis analysis revealed significant differences among finishing protocol groups for both ΔEab (H = 13.21, p < 0.0014) and ΔE00 (H = 9.14, p = 0.0104), with Chroma + Glaze exhibiting the smallest ΔE values (ΔE00 ≈ 0.33) below the perceptibility threshold. Conclusions: The finishing protocol significantly influences the optical behavior of ST zirconia after simulated wear. The Chroma + Glaze group demonstrated the highest color stability and lowest translucency, suggesting enhanced long-term esthetic performance. In contrast, polished zirconia showed greater color variation and an increase in translucency, indicating lower optical stability under brushing abrasion.
背景/目的:超半透明氧化锆(ST氧化锆)越来越多地用于美学修复,但其机械磨损后的光学稳定性尚不清楚。本研究旨在评估抛光、上釉和染色后上釉(Chroma + Glaze)三种处理方案对ST氧化锆模拟刷牙后颜色稳定性和透明度的影响。方法:制作60个氧化锆标本(Vita YZ ST, shade A1),分为抛光组、釉面组和色度+釉面组,每组20个。使用分光光度计(VITA Easyshade V; VITA Zahnfabrik)在10,000次刷刷(200g负载,1.5 Hz)前后测量颜色(L*, a*, b*)。计算半透明参数(TPab, TP00),同时使用CIELAB (ΔEab)和CIEDE2000 (ΔE00)公式评估颜色变化。数据分析采用双因素方差分析和Kruskal-Wallis检验(α = 0.05)。结果:治疗显著影响半透明度(H = 46.79, p < 0.001; H = 21.09, p < 0.001),三组间差异一致。经bonferroni调整后的事后比较显示,Chroma + Glaze的TP00值在两个测量值中都明显低于Glaze (p < 0.0001; p < 0.001),在两个测量值中都低于polishing (p < 0.0001; p = 0.0147)。Kruskal-Wallis分析显示,ΔEab (H = 13.21, p < 0.0014)和ΔE00 (H = 9.14, p = 0.0104)的整理方案组之间存在显著差异,其中Chroma + Glaze在可感知阈值以下的ΔE值最小(ΔE00≈0.33)。结论:处理方案对ST氧化锆模拟磨损后的光学行为有显著影响。色度+釉面组表现出最高的颜色稳定性和最低的半透明性,表明增强的长期审美性能。相比之下,抛光后的氧化锆呈现出更大的颜色变化和半透明增加,表明在刷磨下光学稳定性较低。
{"title":"Effect of Finishing Protocol Treatments on Optical Properties of Super Translucent Zirconia After Simulated Wear.","authors":"Maja Žagar, Ines Kovačić, Robert Pongrac, Robert Ćelić","doi":"10.3390/dj14010003","DOIUrl":"https://doi.org/10.3390/dj14010003","url":null,"abstract":"<p><p><b>Background/Objectives</b>: Super translucent zirconia (ST zirconia) is increasingly used for esthetic restorations, but its optical stability after mechanical wear remains unclear. This study aimed to evaluate the effects of three finishing protocols-polishing, glazing, and staining followed by glazing (Chroma + Glaze)-on the color stability and translucency of ST zirconia after simulated toothbrushing. <b>Methods</b>: Sixty zirconia specimens (Vita YZ ST, shade A1) were fabricated and divided into three groups, namely Polished, Glazed, and Chroma + Glaze (<i>n</i> = 20 in each group). Color (L*, a*, b*) was measured using a spectrophotometer (VITA Easyshade V; VITA Zahnfabrik) before and after 10,000 brushing cycles (200 g load, 1.5 Hz). Translucency parameters (TP<sub>ab</sub>, TP<sub>00</sub>) were calculated, while color changes were assessed using CIELAB (ΔE<sub>ab</sub>) and CIEDE2000 (ΔE<sub>00</sub>) formulas. Data were analyzed using two-way ANOVA and Kruskal-Wallis tests (<i>α</i> = 0.05). <b>Results</b>: Treatment significantly affected translucency (H = 46.79, <i>p</i> < 0.001; H = 21.09, <i>p</i> < 0.001), indicating consistent differences among the three treatment groups. Bonferroni-adjusted post hoc comparisons showed that Chroma + Glaze exhibited significantly lower TP<sub>00</sub> values than Glaze in both measurements (<i>p</i> < 0.0001; <i>p</i> < 0.001), as well as lower values than Polished in both measurements (<i>p</i> < 0.0001; <i>p</i> = 0.0147, respectively). Kruskal-Wallis analysis revealed significant differences among finishing protocol groups for both ΔE<sub>ab</sub> (H = 13.21, <i>p</i> < 0.0014) and ΔE<sub>00</sub> (H = 9.14, <i>p</i> = 0.0104), with Chroma + Glaze exhibiting the smallest ΔE values (ΔE<sub>00</sub> ≈ 0.33) below the perceptibility threshold. <b>Conclusions</b>: The finishing protocol significantly influences the optical behavior of ST zirconia after simulated wear. The Chroma + Glaze group demonstrated the highest color stability and lowest translucency, suggesting enhanced long-term esthetic performance. In contrast, polished zirconia showed greater color variation and an increase in translucency, indicating lower optical stability under brushing abrasion.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"14 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sofía Folguera, Carmen Llena, José Luis Sanz, Leopoldo Forner, María Melo
Background/Objectives: Augmented Reality (AR) is promising in dental education, yet its impact on caries detection training remains underexplored. This study aimed to compare the effect of a web-based AR (WebAR) learning object with a content- and interface-matched interactive 2D presentation on undergraduate students' motivation to learn caries detection. Methods: Two learning objects were expressly designed using a real patient's dental records: a WebAR image-tracking experience (built with Zapworks Studio®) and a 2D interactive presentation (built with Genially®). The WebAR object showed the patient's 3D dental arches with tooth-level hotspots linking clinical and radiographic media. The 2D comparator mirrored the same assets and navigation, restricting visualization to 2D. Third-year dental students were randomly assigned to either the AR or Genially® (G) group. After completing ICDAS-based caries identification, participants completed the 12-item Reduced Instructional Materials Motivation Survey (RIMMS) and provided open-ended feedback. Group differences were tested with the Mann-Whitney U test (p < 0.05). Results: Eighty-five students completed the study (AR n = 46; G n = 39). The AR group achieved a higher total RIMMS score (4.14 vs. 3.53 on a 5-point scale; p < 0.001), with significantly higher means in Attention, Confidence, Satisfaction, and Relevance (p < 0.05). Open-ended comments were more positive with AR (75.8% vs. 31.0%), while graphics-related complaints were more frequent with the Genially® resource (34.5% vs. 75.0%). Conclusions: WebAR achieved higher RIMMS motivation scores than a content-matched interactive presentation. Adding 3D spatial interaction to otherwise equivalent materials can enhance learners' motivation for caries detection training, while remaining low-cost and scalable.
背景/目的:增强现实技术(AR)在牙科教育中很有前景,但其对龋齿检测培训的影响仍未得到充分探讨。本研究旨在比较基于web的AR (WebAR)学习对象与内容和界面匹配的交互式2D演示对大学生龋齿检测学习动机的影响。方法:使用真实患者的牙科记录明确设计了两个学习对象:WebAR图像跟踪体验(使用Zapworks Studio®构建)和2D交互式演示(使用genial®构建)。WebAR对象显示患者的三维牙弓,牙齿水平的热点连接临床和放射介质。2D比较器反映了相同的资产和导航,将可视化限制为2D。三年级牙科学生随机分为AR组和genally®(G)组。在完成基于icdas的龋病识别后,参与者完成了12项精简教学材料动机调查(RIMMS),并提供开放式反馈。组间差异采用Mann-Whitney U检验(p < 0.05)。结果:85名学生完成了研究(AR n = 46; G n = 39)。AR组获得了更高的RIMMS总分(5分制4.14比3.53,p < 0.001),在注意力、信心、满意度和相关性方面的平均值显著高于AR组(p < 0.05)。开放式评论在AR中更为积极(75.8%对31.0%),而图形相关的投诉在genial®资源中更为频繁(34.5%对75.0%)。结论:WebAR比内容匹配的交互式演示获得更高的RIMMS动机得分。将三维空间互动添加到其他等效材料中可以增强学习者对龋齿检测培训的动机,同时保持低成本和可扩展性。
{"title":"Web-Based Augmented Reality vs. Interactive Presentation for Learning Caries Detection: A Randomized Study on Student Motivation.","authors":"Sofía Folguera, Carmen Llena, José Luis Sanz, Leopoldo Forner, María Melo","doi":"10.3390/dj14010001","DOIUrl":"https://doi.org/10.3390/dj14010001","url":null,"abstract":"<p><p><b>Background/Objectives</b>: Augmented Reality (AR) is promising in dental education, yet its impact on <i>caries detection</i> training remains underexplored. This study aimed to compare the effect of a web-based AR (WebAR) learning object with a content- and interface-matched interactive 2D presentation on undergraduate students' motivation to learn caries detection. <b>Methods</b>: Two learning objects were expressly designed using a real patient's dental records: a WebAR image-tracking experience (built with Zapworks Studio<sup>®</sup>) and a 2D interactive presentation (built with Genially<sup>®</sup>). The WebAR object showed the patient's 3D dental arches with tooth-level hotspots linking clinical and radiographic media. The 2D comparator mirrored the same assets and navigation, restricting visualization to 2D. Third-year dental students were randomly assigned to either the AR or Genially<sup>®</sup> (G) group. After completing ICDAS-based caries identification, participants completed the 12-item Reduced Instructional Materials Motivation Survey (RIMMS) and provided open-ended feedback. Group differences were tested with the Mann-Whitney U test (<i>p</i> < 0.05). <b>Results</b>: Eighty-five students completed the study (AR n = 46; G n = 39). The AR group achieved a higher total RIMMS score (4.14 vs. 3.53 on a 5-point scale; <i>p</i> < 0.001), with significantly higher means in Attention, Confidence, Satisfaction, and Relevance (<i>p</i> < 0.05). Open-ended comments were more positive with AR (75.8% vs. 31.0%), while graphics-related complaints were more frequent with the Genially<sup>®</sup> resource (34.5% vs. 75.0%). <b>Conclusions</b>: WebAR achieved higher RIMMS motivation scores than a content-matched interactive presentation. Adding 3D spatial interaction to otherwise equivalent materials can enhance learners' motivation for caries detection training, while remaining low-cost and scalable.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"14 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mélody Dutot, Marie Le Besco, Océane Mathurin, Shao-Bing Fong, Vincent Meuric, Caroline Tanter
Background/Objectives: This study aimed to investigate the effects of a new alcohol-free marine mouthwash containing an algae extract, a coastal plant extract, and seawater on plaque reduction, gingivitis, and oral microbiota balance. Methods: In a single-center, prospective, randomized comparative study, 50 subjects with gingivitis were assigned to either a marine mouthwash group (Test, n = 26) or a marketed mouthwash group (Comparator, n = 24). Clinical assessments included plaque, gingivitis, halitosis, and volunteer self-evaluation at baseline (T0) and after 7 days (T7). Gingival microbiota was sampled using swabs at baseline (T0) and after 7 days (T7). Conclusions: Both groups demonstrated reductions in dental plaque, gingivitis, and halitosis at T7 compared to baseline. Improvements in halitosis were observed in both groups but did not reach statistical significance. Microbiota analysis revealed that the Test group experienced the enrichment of health-associated bacterial taxa and a reduction in disease-associated species, notably Porphyromonas endodontalis, while the Comparator group showed an increase in pathogenic taxa. The marine mouthwash was well tolerated and positively rated by participants. Combining an algae extract, a coastal plant extract, and seawater, it effectively reduces plaque and gingivitis and may contribute to oral microbiota balance. It represents a promising alternative to conventional chemical oral care products.
背景/目的:本研究旨在探讨一种新型含藻类提取物、海岸植物提取物和海水的无酒精海洋漱口水对牙菌斑减少、牙龈炎和口腔微生物群平衡的影响。方法:在一项单中心、前瞻性、随机比较研究中,50名牙龈炎患者被分配到海洋漱口水组(Test, n = 26)和市售漱口水组(Comparator, n = 24)。临床评估包括牙菌斑、牙龈炎、口臭和志愿者在基线(T0)和7天后(T7)的自我评价。在基线(T0)和7天后(T7)使用拭子取样牙龈微生物群。结论:与基线相比,两组在T7时均表现出牙菌斑、牙龈炎和口臭的减少。两组患者口臭均有改善,但无统计学意义。微生物群分析显示,测试组经历了健康相关细菌分类群的丰富和疾病相关物种的减少,特别是牙髓卟啉单胞菌,而比较组显示了致病分类群的增加。海洋漱口水的耐受性良好,并得到了参与者的积极评价。结合海藻提取物,海岸植物提取物和海水,有效地减少菌斑和牙龈炎,并可能有助于口腔微生物群平衡。它代表了传统化学口腔护理产品的一个有前途的替代品。
{"title":"Control of Dental Plaque and Gingival Inflammation by Natural Ingredients-Based Mouthwash.","authors":"Mélody Dutot, Marie Le Besco, Océane Mathurin, Shao-Bing Fong, Vincent Meuric, Caroline Tanter","doi":"10.3390/dj14010002","DOIUrl":"https://doi.org/10.3390/dj14010002","url":null,"abstract":"<p><p><b>Background/Objectives</b>: This study aimed to investigate the effects of a new alcohol-free marine mouthwash containing an algae extract, a coastal plant extract, and seawater on plaque reduction, gingivitis, and oral microbiota balance. <b>Methods</b>: In a single-center, prospective, randomized comparative study, 50 subjects with gingivitis were assigned to either a marine mouthwash group (Test, <i>n</i> = 26) or a marketed mouthwash group (Comparator, <i>n</i> = 24). Clinical assessments included plaque, gingivitis, halitosis, and volunteer self-evaluation at baseline (T0) and after 7 days (T7). Gingival microbiota was sampled using swabs at baseline (T0) and after 7 days (T7). <b>Conclusions</b>: Both groups demonstrated reductions in dental plaque, gingivitis, and halitosis at T7 compared to baseline. Improvements in halitosis were observed in both groups but did not reach statistical significance. Microbiota analysis revealed that the Test group experienced the enrichment of health-associated bacterial taxa and a reduction in disease-associated species, notably <i>Porphyromonas endodontalis</i>, while the Comparator group showed an increase in pathogenic taxa. The marine mouthwash was well tolerated and positively rated by participants. Combining an algae extract, a coastal plant extract, and seawater, it effectively reduces plaque and gingivitis and may contribute to oral microbiota balance. It represents a promising alternative to conventional chemical oral care products.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"14 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}