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Corrigendum. 更正。
IF 3.2 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-10-01 Epub Date: 2024-07-02 DOI: 10.1097/DCR.0000000000003438
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引用次数: 0
Deep Learning-Based Real-Time Ureter Identification in Laparoscopic Colorectal Surgery. 基于深度学习的腹腔镜结直肠手术中输尿管实时识别。
IF 3.2 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-10-01 Epub Date: 2024-07-03 DOI: 10.1097/DCR.0000000000003335
Satoshi Narihiro, Daichi Kitaguchi, Hiro Hasegawa, Nobuyoshi Takeshita, Masaaki Ito

Background: Iatrogenic ureteral injury is a serious complication of abdominopelvic surgery. Identifying the ureters intraoperatively is essential to avoid iatrogenic ureteral injury. We developed a model that may minimize this complication.

Impact of innovation: We applied a deep learning-based semantic segmentation algorithm to the ureter recognition task and developed a deep learning model called UreterNet. This study aimed to verify whether the ureters could be identified in videos of laparoscopic colorectal surgery.

Technology, materials, and methods: Semantic segmentation of the ureter area was performed using a convolutional neural network-based approach. Feature Pyramid Networks were used as the convolutional neural network architecture for semantic segmentation. Precision, recall, and the Dice coefficient were used as the evaluation metrics in this study.

Preliminary results: We created 14,069 annotated images from 304 videos, with 9537, 2266, and 2266 images in the training, validation, and test data sets, respectively. Concerning ureter recognition performance, the precision, recall, and Dice coefficient for the test data were 0.712, 0.722, and 0.716, respectively. Regarding the real-time performance on recorded videos, it took 71 milliseconds for UreterNet to infer all pixels corresponding to the ureter from a single still image and 143 milliseconds to output and display the inferred results as a segmentation mask on the laparoscopic monitor.

Conclusions: UreterNet is a noninvasive method for identifying the ureter in videos of laparoscopic colorectal surgery and can potentially improve surgical safety.

Future directions: Although this deep learning model could lead to the development of an image-navigated surgical system, it is necessary to verify whether UreterNet reduces the occurrence of iatrogenic ureteral injury.

背景:输尿管先天性损伤是腹盆腔手术的一种严重并发症。术中识别输尿管是避免输尿管先天性损伤的关键。在此,我们开发了一种模型,可将这种并发症降至最低:我们将基于深度学习的语义分割算法应用于输尿管识别任务,并开发了一个名为 UreterNet 的深度学习模型。本研究旨在验证能否在腹腔镜结直肠手术视频中识别出输尿管:使用基于卷积神经网络的方法对输尿管区域进行语义分割。特征金字塔网络被用作语义分割的卷积神经网络架构。本研究采用精确度、召回率和骰子系数作为评价指标:我们从 304 个视频中创建了 14,069 张注释图像,其中训练、验证和测试数据集分别有 9537 张、2266 张和 2266 张图像。在输尿管识别性能方面,测试数据的精确度、召回率和 Dice 系数分别为 0.712、0.722 和 0.716。在录制视频的实时性能方面,UreterNet 从一张静止图像中推断出输尿管对应的所有像素需要 71 毫秒,将推断结果作为分割掩码输出并显示在腹腔镜显示器上需要 143 毫秒:UreterNet 是一种在腹腔镜结直肠手术视频中识别输尿管的无创方法,有可能提高手术安全性。虽然这可能导致图像导航手术系统的开发,但有必要验证输尿管网是否能减少输尿管先天性损伤的发生。
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引用次数: 0
Expert Commentary on "Prehabilitation for Colorectal Cancer Surgery". 专家评论 "结直肠癌手术前康复"。
IF 3.2 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-10-01 Epub Date: 2024-07-17 DOI: 10.1097/DCR.0000000000003471
Marylise Boutros
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引用次数: 0
Research Perspective on: Association Between Cross-Stapling Technique in Mechanical Colorectal Anastomosis and Short-term Outcomes. 机械性结直肠吻合术中交叉缝合技术与短期疗效的关系
IF 3.2 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-10-01 Epub Date: 2024-06-26 DOI: 10.1097/DCR.0000000000003420
Jonathan S Abelson
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引用次数: 0
Perspective on the PROSPECT: The Conundrum of Managing T3n0-N1 Mid and Upper Rectal Cancer. 透视 PROSPECT:治疗 T3n0-N1 中上段直肠癌的难题。
IF 3.2 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-10-01 Epub Date: 2024-07-17 DOI: 10.1097/DCR.0000000000003291
Amr Aref, Ahmed Abdalla, Jasneet S Bhullar, Elon Knoll
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引用次数: 0
What Every Colorectal Surgeon Should Know About the Updated Medicare Access and Children's Healthcare Insurance Program Reauthorization Act and the Merit-Based Incentive Program System Legislation. 每个结直肠外科医生都应了解的最新《医疗保险和儿童医疗保险计划再授权法案》和《基于业绩的激励计划系统立法》。
IF 3.2 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-10-01 Epub Date: 2024-07-03 DOI: 10.1097/DCR.0000000000003448
Dimitra Theodoropoulos, Shankar Raman, Donald B Colvin
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引用次数: 0
Indocyanine Green Fluorescence Imaging-Guided Laparoscopic Right Hemicolectomy With Complete Mesocolic Excision and Central Vascular Ligation and Transvaginal Specimen Extraction. 吲哚菁绿荧光成像引导的腹腔镜右半结肠切除术,伴有完整的中结肠切除、中央血管结扎和经阴道标本提取。
IF 3.2 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-10-01 Epub Date: 2024-07-05 DOI: 10.1097/DCR.0000000000003349
Hongming Li, Xiaochuang Feng, Dechang Diao
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引用次数: 0
GI Polyps and Polyposis in Individuals Harboring Germline CHEK2 Mutations. 携带遗传性 CHEK2 基因突变者的胃肠道息肉和息肉病。
IF 3.2 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-10-01 Epub Date: 2024-07-03 DOI: 10.1097/DCR.0000000000003365
Corey Chang, John E Lee, Kevin M Waters, Brent K Larson
<p><strong>Background: </strong>Checkpoint kinase 2 is a tumor suppressor gene in the DNA damage checkpoint system that may be mutated in several cancers. Patients with germline checkpoint kinase 2 mutations and multiple colon polyps were noted during routine care, and genetic testing is recommended for patients with as few as 10 lifetime polyps.</p><p><strong>Objective: </strong>This study assessed whether checkpoint kinase 2 is associated with attenuated or oligopolyposis and characterized the GI clinicopathologic profile.</p><p><strong>Design: </strong>Retrospective observational study.</p><p><strong>Settings: </strong>Records from patients harboring germline checkpoint kinase 2 mutations from 1999 to 2020 were reviewed.</p><p><strong>Patients: </strong>A total of 45 patients with germline checkpoint kinase 2 mutations with endoscopic examinations.</p><p><strong>Main outcome measures: </strong>Description of clinicopathologic variables.</p><p><strong>Results: </strong>Twenty-five of 45 patients had polyps: 3 with only upper GI polyps, 17 with only lower GI polyps, and 5 with both upper and lower GI polyps. The most common germline checkpoint kinase 2 mutations in patients with polyps were p.S428F (n = 10), p.I157T (n = 4), and p.T476M (n = 2), with other mutations present in 1 patient each. Among patients with lower GI polyps, 9 had adenomas, 6 had serrated polyps, 1 had an inflammatory polyp, and 6 had both adenomatous and serrated polyps. Three patients (p.I157T, n = 2; p.R117G, n = 1) had more than 10 adenomas and 1 (p.G259fs) had 18 serrated polyps. Five patients (11.1%) developed colorectal adenocarcinoma, including 2 with more than 10 adenomas. Five patients with p.S428F (50%) exclusively had right-sided adenomas.</p><p><strong>Limitations: </strong>Single-center descriptive study.</p><p><strong>Conclusions: </strong>Germline checkpoint kinase 2 mutations should be considered in patients with polyposis. The preponderance of right-sided adenomas in patients with p.S428F mutations suggests the importance of right-sided colonoscopy in these patients. See Video Abstract .</p><p><strong>Plipos y poliposis gastrointestinales en individuos que albergan mutaciones en la lnea germinal del gen chek: </strong>ANTECEDENTES:El punto de control quinasa 2 (CHEK2) es un gen supresor de tumores en el sistema de puntos de control de daño del ácido desoxirribonucleico (ADN) que puede mutar en varios cánceres. Durante la atención de rutina se observaron pacientes con mutaciones de la línea germinal CHEK2 y múltiples pólipos en el colon, y se recomiendan pruebas genéticas para pacientes con al menos 10 pólipos en su vida.OBJETIVO:Este estudio evaluó si CHEK2 está asociado con poliposis atenuada u oligopoliposis y caracterizó el perfil clínico-patológico gastrointestinal (GI).DISEÑO:Estudio observacional retrospectivo.ESCENARIO:Se revisaron los registros de pacientes que albergaban mutaciones de la línea germinal CHEK2 de 1999 a 2020.PACIENTES:45 pacientes co
背景:检查点激酶 2 是脱氧核糖核酸损伤检查点系统中的肿瘤抑制基因,可能在多种癌症中发生突变。在常规治疗过程中,发现了检查点激酶 2 基因突变和多发性结肠息肉患者,建议对终生息肉少至 10 个的患者进行基因检测:本研究评估了检查点激酶 2 是否与减数或少数息肉病相关,并描述了胃肠道临床病理特征:设计:回顾性观察研究:回顾了1999-2020年间携带种系检查点激酶2突变的患者记录:主要结果指标:临床病理变量描述:结果:45例患者中有25例患有息肉:结果:45例患者中有25例患有息肉:3例仅有上消化道息肉,17例仅有下消化道息肉,5例同时有上消化道和下消化道息肉。息肉患者中最常见的种系检查点激酶2突变是p.S428F(10例)、p.I157T(4例)和p.T476M(2例),其他突变各有1例。在下消化道息肉患者中,9 人患有腺瘤,6 人患有锯齿状息肉,1 人患有炎性息肉,6 人同时患有腺瘤性息肉和锯齿状息肉。3 名患者(p.I157T,n = 2;p.R117G,n = 1)的腺瘤数量大于 10 个,1 名患者(p.G259fs)有 18 个锯齿状息肉。5名患者(11.1%)患上了结直肠腺癌,其中2人的腺瘤数量超过10个。5名p.S428F患者(50%)只患右侧腺瘤:局限性:单中心描述性研究:结论:应考虑息肉病患者的基因检查点激酶 2 突变。p.S428F突变患者中右侧腺瘤居多,这表明对这些患者进行右侧结肠镜检查非常重要。参见视频摘要。
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引用次数: 0
Evaluating the Application of Nail Polish as an Ostomy Baseplate: A Comparative Analysis With Conventional Ostomy Pastes in the Market and a Clinical Trial. 评估指甲油作为造口底板的应用:与市场上和临床试验中的传统造口糊剂的比较分析。
IF 3.2 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-10-01 Epub Date: 2024-07-08 DOI: 10.1097/DCR.0000000000003446
Fatemeh Chinisaz, Seyed Amir Miratashi Yazdi, Hadi Ahmadi Amoli, Leyla Sahebi
<p><strong>Background: </strong>Peristomal skin complications are prevalent among patients with ostomies and significantly impact their quality of life. Ostomy care is crucial for patients with ostomies because it ensures proper adhesion and protects and reduces the peristomal skin complications.</p><p><strong>Objectives: </strong>To assess the effectiveness of nail polish as a novel skin barrier and compare its performance with the commonly available ostomy barriers in the market.</p><p><strong>Design: </strong>Phase I randomized controlled trial.</p><p><strong>Settings: </strong>A single trauma and surgery center.</p><p><strong>Patients: </strong>Forty patients who were hospitalized for ostomy implantation were enrolled. Twenty cases were included in each group.</p><p><strong>Main outcome measures: </strong>The use of nail polish as a baseplate was tested against the common ostomy pastes. Over 6 months, the study enrolled 40 patients who required loop ileostomy and were followed up for 8 weeks. Postoperative evaluation was performed using the City of Hope-Quality of Life ostomy and 36-Item Short Form questionnaires, as well as physical examinations conducted 1 day after surgery and at 4 and 8 weeks after surgical treatment.</p><p><strong>Results: </strong>Forty patients were included in the study. At all 3 time points, significant differences were observed in 36-Item Short Form scores, time, and costs spent on ostomy care. The intervention group experienced fewer peristomal skin complications (skin itching, redness, inflammation, and burning) and skin allergies at the first and second time points (p < 0.05). Furthermore, none of the patients in the intervention or control group experienced rare complications such as folliculitis, candidiasis, contact dermatitis, or pyoderma gangrenosum.</p><p><strong>Limitations: </strong>Single institution.</p><p><strong>Conclusions: </strong>The utilization of nail polish as a baseplate reduces skin allergies, peristomal skin complications, and the time and financial resources spent on ostomy care. Furthermore, using nail polish has demonstrated promising results in patients' quality of life. Consequently, using nail polish emerged as the preferred choice among study participants. See the Video Abstract .</p><p><strong>Evaluando la aplicacin de esmalte de uas como placa base de ostoma un anlisis comparativo con pastas de ostoma convencionales en el mercado en un ensayo clnico: </strong>ANTECEDENTES:Las complicaciones de la piel periestomal son frecuentes entre los pacientes con ostomías y afectan significativamente su calidad de vida. Los cuidados de la ostomía son cruciales para los pacientes ostomizados, ya que garantizan una adhesión adecuada y protegen y reducen las complicaciones de la piel periestomal.OBJETIVOS:Evaluar la eficacia del esmalte de uñas como nueva barrera cutánea y comparar su rendimiento con las barreras de ostomía comúnmente disponibles en el mercado.DISEÑO:Ensayo clínico aleatorizado de
背景:造口周围皮肤并发症在造口患者中很普遍,严重影响他们的生活质量。造口护理对造口患者至关重要,因为它能确保正确粘合,保护并减少造口周围皮肤并发症:评估指甲油作为新型皮肤屏障的有效性,并将其性能与市场上常见的造口屏障进行比较:设计:I期随机对照试验:设置:一家创伤和外科中心:患者:40 名住院接受造口植入术的患者。每组 20 例:使用指甲油作为底板与普通造口糊剂进行了对比试验。在 6 个月的时间里,该研究共招募了 40 名需要环状回肠造口术的患者,并对他们进行了 8 周的随访。术后评估采用希望之城生活质量造口问卷和 SF-36 问卷,以及术后 1 天、4 周和 8 周的体格检查:研究共纳入 40 名患者。在所有 3 个时间点上,SF-36 评分、造口护理时间和费用均有显著差异。干预组在第一和第二个时间点出现的造口周围皮肤并发症(皮肤瘙痒、发红、发炎和灼痛)以及皮肤过敏的情况较少(P < 0.05)。此外,干预组和对照组患者均未出现毛囊炎、念珠菌病、接触性皮炎或脓皮病等罕见并发症:局限性:单个机构:使用指甲油作为底板可减少皮肤过敏、肛周皮肤并发症以及造口护理所花费的时间和经济资源。此外,使用指甲油还能提高患者的生活质量。因此,使用指甲油成为研究参与者的首选。观看视频。
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引用次数: 0
Bowel Dysfunction After Colon Cancer Surgery: A Prospective, Longitudinal, Multicenter Study. 结肠癌手术后的肠道功能障碍:一项前瞻性纵向多中心研究
IF 3.2 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-10-01 Epub Date: 2024-06-20 DOI: 10.1097/DCR.0000000000003358
Sofia J Sandberg, Jennifer M Park, Viktor A Tasselius, Eva Angenete
<p><strong>Background: </strong>Longitudinal studies on functional outcomes after colon resection are limited.</p><p><strong>Objective: </strong>To evaluate bowel dysfunction and related distress 1 and 3 years after colon resection using the low anterior resection syndrome score as well as specific validated items.</p><p><strong>Design: </strong>This study presents the long-term results of bowel dysfunction and related distress based on the Quality of Life in Colon Cancer study, an observational, prospective multicenter study of patients with newly diagnosed colon cancer.</p><p><strong>Settings: </strong>The study was conducted at 21 Swedish and Danish surgical centers between 2015 and 2019.</p><p><strong>Patients: </strong>All patients who underwent right-sided or left-sided colon resection were considered eligible. Exclusion criteria were age younger than 18 years, cognitive impairment, or inability to understand Swedish/Danish. Patients completed extensive questionnaires at diagnosis and after 1 and 3 years. Clinical data were supplemented by national quality registries.</p><p><strong>Main outcome measures: </strong>The low anterior resection syndrome score, specific bowel symptoms, and patient-reported distress were assessed.</p><p><strong>Results: </strong>Of 1221 patients (83% response rate), 17% reported major low anterior resection syndrome 1 year after either type of resection; this finding was consistent at 3 years (17% right, 16% left). In the long-term, the only significant difference between types of resections was a high occurrence of loose stools after right-sided resections. Overall, less than one-fifth of patients experienced distress, with women reporting more frequent symptoms and greater distress. In particular, incontinence and loose stools correlated strongly with distress.</p><p><strong>Limitations: </strong>Absence of prediagnosis bowel function data.</p><p><strong>Conclusions: </strong>Our study indicates that bowel function remains largely intact after colon resection, with only a minority reporting significant distress. Adverse outcomes were more common among women. The occurrence of loose stools after right-sided resection and the association between incontinence, loose stools, and distress highlights a need for postoperative evaluations and more thorough assessments beyond the low anterior resection syndrome score when evaluating patients with colon cancer. See the Video Abstract .</p><p><strong>Disfuncionamiento intestinal despus de la ciruga por cncer de colon estudio prospectivo, longitudinal y multicntrico: </strong>ANTECEDENTES:Los estudios longitudinales sobre el resultado funcional después de una resección cólica son limitados.OBJETIVO:Examinar la disfunción intestinal y el malestar relacionado uno y tres años después de la resección del colon utilizando la puntuación de referencia en el síndrome de resección anterior baja (LARS), así como otros ítems de validez específica.DISEÑO:Este estudio presenta los resul
背景:有关结肠切除术后功能预后的纵向研究十分有限:有关结肠切除术后功能结果的纵向研究非常有限:利用低位前切除综合征评分以及特定的验证项目,研究结肠切除术后一年和三年的肠道功能障碍及相关痛苦:本研究介绍了基于结肠癌生活质量研究的肠道功能障碍和相关痛苦的长期结果,该研究是一项针对新诊断结肠癌患者的观察性、前瞻性多中心研究:研究于2015年至2019年期间在瑞典和丹麦的21个外科中心进行:所有接受右侧或左侧结肠切除术的患者均符合条件。排除标准为年龄低于 18 岁、认知障碍或无法理解瑞典语/丹麦语。患者在确诊时以及一年和三年后填写了大量问卷。临床数据由国家质量登记处补充:主要结果测量:评估低位前切除综合征评分、特定肠道症状和患者报告的痛苦:在1221名患者中(回复率为83%),17%的患者在两种切除术一年后报告了严重的低位前切除综合征,3年后情况一致(右侧17%,左侧16%)。从长期来看,不同类型切除术的唯一显著区别是右侧切除术后大便稀溏的发生率较高。总体而言,不到五分之一的患者感到痛苦,女性患者的症状更频繁,痛苦更大。尤其是尿失禁和大便稀烂与痛苦密切相关:缺乏诊断前的肠功能数据:我们的研究表明,结肠切除术后肠道功能基本保持完好,只有少数人报告有明显不适。不良后果在女性中更为常见。右侧切除术后出现稀便以及大小便失禁、稀便和痛苦之间的联系突出表明,在评估结肠癌患者时,除了 LARS 评分外,还需要进行术后评估和更全面的评估。参见视频摘要。
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引用次数: 0
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Diseases of the Colon & Rectum
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