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Prognostic Factors and Long-term Outcomes in Patients With Colorectal Peritoneal Metastases Treated With Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Retrospective Cohort Study From a Tertiary Care Center in India. 经细胞减少手术和腹腔内高温化疗治疗的结直肠腹膜转移患者的预后因素和长期预后:来自印度三级保健中心的回顾性队列研究。
IF 3.7 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2026-01-01 Epub Date: 2025-10-24 DOI: 10.1097/DCR.0000000000003995
Manisha Aggarwal, Abhishek Aggarwal, Shaifali Goel, Sumit Goyal, Prerna Garg, Gurudutt Gupta, Shivendra Singh
<p><strong>Background: </strong>Colorectal peritoneal metastases are associated with poor prognosis. Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy may improve survival in selected patients.</p><p><strong>Purpose: </strong>To evaluate survival outcomes and identify prognostic factors affecting overall survival and disease-free survival in patients with colorectal peritoneal metastases undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.</p><p><strong>Design: </strong>Retrospective cohort study.</p><p><strong>Settings: </strong>This study was conducted at a single tertiary referral center between January 2013 and March 2024.</p><p><strong>Patients: </strong>Ninety-two patients with colorectal peritoneal metastases treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy were included. The cohort comprised 52 men and 40 women with a mean age of 46 years. Synchronous metastases were present in 75% of cases.</p><p><strong>Interventions: </strong>All patients underwent cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy.</p><p><strong>Main outcome measures: </strong>Overall survival, disease-free survival, and prognostic factors influencing outcomes were the main outcome measures.</p><p><strong>Results: </strong>Complete cytoreduction was achieved in 92.3% of patients. The median overall survival was 24 months, and the median disease-free survival was 11 months. The 3- and 5-year overall survival rates were 43.6% and 32.2%, respectively. An increased Peritoneal Cancer Index was independently associated with decreased overall survival, with poorer outcomes observed for a Peritoneal Cancer Index greater than 16 (HR 1.06, p = 0.016). The presence of perineural invasion (HR 2.06, p = 0.030) and intraoperative blood loss >1500 mL (HR 1.96, p = 0.018) were also associated with reduced survival. These factors may help stratify patients for optimal surgical outcomes.</p><p><strong>Limitations: </strong>Retrospective design, single-center experience, and limited molecular data may affect generalizability. Longer follow-up is needed to evaluate late recurrences and long-term survival.</p><p><strong>Conclusions: </strong>Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy improves survival in selected patients with colorectal peritoneal metastases. High Peritoneal Cancer Index, perineural invasion, and excessive blood loss predict poorer outcomes and should guide patient selection. See Video Abstract .</p><p><strong>Factores pronsticos y resultados a largo plazo en pacientes con metstasis peritoneales colorrectales tratados con ciruga citorreductora y quimioterapia intraperitoneal hipertrmica un estudio de cohorte retrospectivo de un centro de atencin terciaria en la india: </strong>ANTECEDENTES:Las metástasis peritoneales colorrectales se asocian con un mal pronóstico. La cirugía citorreductora combinada con quimioterapia intraperitoneal hi
背景:结直肠腹膜转移与预后不良相关。细胞减少手术联合腹腔内高温化疗可能提高某些患者的生存率。目的:评估结肠直肠腹膜转移患者接受细胞减少手术和腹腔内高温化疗的生存结果,并确定影响总生存和无病生存的预后因素。设计:回顾性队列研究。背景:本研究于2013年1月至2024年3月在单一三级转诊中心进行。患者:92例结直肠腹膜转移患者接受细胞减缩手术和腹腔内高温化疗。该队列包括52名男性和40名女性,平均年龄为46岁。75%的病例出现同步转移。干预措施:所有患者均行细胞减缩手术,随后行腹腔热化疗。主要结局指标:总生存期、无病生存期和影响结局的预后因素。结果:92.3%的患者细胞完全减少。中位总生存期为24个月,中位无病生存期为11个月。3年和5年总生存率分别为43.6%和32.2%。腹膜癌指数升高与总生存率降低独立相关,当腹膜癌指数大于16时,观察到预后较差(风险比1.06,p = 0.016)。神经周围侵犯(风险比2.06,p = 0.030)和术中出血量超过1500毫升(风险比1.96,p = 0.018)也与生存率降低有关。这些因素可能有助于对患者进行分层以获得最佳手术结果。局限性:回顾性设计、单中心经验和有限的分子数据可能影响通用性。需要更长的随访来评估晚期复发和长期生存。结论:细胞减少手术联合腹腔内高温化疗可提高结肠直肠腹膜转移患者的生存率。高腹膜癌指数、神经周围浸润和失血过多预示较差的预后,应指导患者选择。参见视频摘要。
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引用次数: 0
Diagnosis and Management of Rectoceles. 直肠前突的诊断和治疗。
IF 3.7 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2026-01-01 Epub Date: 2025-10-20 DOI: 10.1097/DCR.0000000000003992
Yeqian Huang, Cherry E Koh
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引用次数: 0
Medial Psoas Space Approach for Robotic En Bloc Pelvic Lymph Node Dissection for Anal Canal Melanoma. 腰大肌内侧间隙入路用于肛管黑色素瘤机器人整体盆腔淋巴结清扫。
IF 3.7 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2026-01-01 Epub Date: 2025-10-06 DOI: 10.1097/DCR.0000000000003807
Yogesh Bansod, Ashwin L Desouza, Avanish Saklani
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引用次数: 0
A Significant Proportion of Stage II and III Rectal Cancers, Selected by Precision Magnetic Resonance, Can Safely Be Managed by Upfront Total Mesorectal Excision Surgery Without Neoadjuvant Therapy. 相当比例的II期和III期直肠癌,通过精确磁共振选择,可以安全地通过术前全直肠肠系膜切除手术而无需新辅助治疗。
IF 3.7 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2026-01-01 Epub Date: 2025-10-24 DOI: 10.1097/DCR.0000000000003987
Laura M Fernandez, José Moreira Azevedo, Ines Santiago, Mireia Castillo-Martin, Barbara Cardoso, Carlos T Carvalho, Richard J Heald, Amjad Parvaiz
<p><strong>Background: </strong>Rectal cancer management has evolved, with neoadjuvant chemoradiotherapy accepted as the criterion standard for locally advanced tumors, reducing local recurrence but at the cost of the detrimental effects of radiation. In addition, neoadjuvant therapy has failed to improve survival. Total neoadjuvant therapy may lower metastasis rates but increase toxicity. Currently, most international guidelines recommend routine use of total neoadjuvant therapy for stage II/III rectal cancer.Magnetic resonance staging may be used to identify patients at low risk for local recurrence after high-quality total mesorectal surgery and selective adjuvant chemotherapy.</p><p><strong>Objective: </strong>Analyze oncological outcomes in patients with stage II and III rectal cancer selected for upfront surgery based on refined magnetic resonance criteria.</p><p><strong>Design: </strong>Retrospective analysis of a prospective database.</p><p><strong>Settings: </strong>Patients with rectal cancer from a single tertiary institution undergoing upfront resection between September 2013 and May 2024.</p><p><strong>Patients: </strong>Patients had clinical stage II/III rectal cancer (mrT3/T4 and/or mrN + tumors) with clear mesorectal fascia (>1 mm). The hypothesis was that in selected patients who would otherwise be candidates for routine total neoadjuvant therapy based on international guidelines, upfront surgery may achieve excellent local disease control, thereby minimizing the benefits of preoperative radiation therapy or chemotherapy.</p><p><strong>Main outcome measures: </strong>Local recurrence-free survival, negative resection margin, and distant metastasis-free survival were the main outcome measures.</p><p><strong>Results: </strong>Among 322 patients, 141 underwent upfront surgery, 94 of whom harbored stage II/III rectal cancer and constituted the population of our study. The median distance of the tumor to the anorectal ring was 47 mm. R0 was achieved in 99%. Local recurrence-free survival at 3 years was 100% and at 5 years was 97%. Three-year and 5-year distant metastasis-free survival were 87% and 81%, respectively. Overall survival at 3 and 5 years was 97% and 95%, with a median follow-up of 34.5 months.</p><p><strong>Limitations: </strong>Retrospective analysis, single-center data.</p><p><strong>Conclusions: </strong>Patients who underwent upfront surgery with high-quality total mesorectal excision as identified by high-resolution MRI achieved excellent oncological outcomes, making neoadjuvant therapy unnecessary in a subset of stage II/III rectal cancers with clear mesorectal fascia. See Video Abstract .</p><p><strong>Una proporcin significativa de cnceres rectales en estadio ii y iii, seleccionados mediante resonancia magntica de precisin, pueden tratarse de forma segura mediante ciruga de extirpacin mesorrectal total inicial sin terapia neoadyuvante: </strong>ANTECEDENTES:El tratamiento del cáncer rectal ha evolucionado, y la qui
背景:直肠癌的治疗已经发生了变化,新辅助放化疗被认为是局部晚期肿瘤的金标准,减少了局部复发,但以辐射的有害影响为代价。此外,新辅助治疗未能提高生存率。总的新辅助治疗可能降低转移率,但增加毒性。目前,大多数国际指南建议II/III期直肠癌常规使用全面新辅助治疗。磁共振分期可以选择高质量全肠系膜手术和选择性辅助化疗后局部复发风险低的患者。目的:分析基于精细磁共振标准选择进行前期手术的II期和III期直肠癌患者的肿瘤预后。设计:前瞻性数据库的回顾性分析。研究背景:2013年9月至2024年5月期间,来自单一三级机构接受前期切除术的直肠癌患者。患者:临床II/III期(mrT3/T4和/或mrN+肿瘤),直肠系膜筋膜清晰(bbb10 1mm)。我们的假设是,根据国际指导方针,对于那些本应接受常规全新辅助治疗的选定患者,前期手术可以实现良好的局部疾病控制,从而最大限度地减少术前放疗或化疗的益处。结果:局部无复发生存,阴性切除边缘和远处无转移生存。结果:322例患者中,141例接受了前期手术。94个处于II/III期,构成我们研究的人口。肿瘤至肛肠环的中位距离为47mm。R0达到99%。3年无局部复发生存率为100%,5年生存率为97%。3年和5年无远处转移生存率分别为87%和81%。3年和5年的总生存率分别为97%和95%,中位随访时间为34.5个月。局限性:回顾性分析,单中心数据。结论:高分辨率磁共振选择的高质量全肠系膜切除的前期手术获得了良好的肿瘤学结果,使得对II/III期直肠肠系膜清晰的直肠癌不需要新辅助治疗。参见视频摘要。
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引用次数: 0
Selected Abstracts. 选定的抽象。
IF 3.7 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2026-01-01 Epub Date: 2025-10-20 DOI: 10.1097/DCR.0000000000003991
Mayin Lin, Scott Dolejs, Norbert Garcia-Henriquez, Rishi Batra
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引用次数: 0
January 2026 Translations. 2026年1月翻译
IF 3.7 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2026-01-01 Epub Date: 2025-12-23 DOI: 10.1097/DCR.0000000000004068
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引用次数: 0
Beyond the Cutoff: Outcomes After Sigmoid Colon Vaginoplasty in Patients With BMI ≥35. BMI≥35患者乙状结肠阴道成形术后的预后
IF 3.7 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2026-01-01 Epub Date: 2025-10-24 DOI: 10.1097/DCR.0000000000003994
Isabel Snee, Sami Ferdousian, Rachel N Rohrich, Ryan P Lin, Christian X Lava, Anusha Singh, Ilana G Margulies, Kenneth L Fan, David M Lisle, Gabriel A Del Corral
<p><strong>Background: </strong>Sigmoid colon vaginoplasty is a gender-affirming procedure offering a self-lubricating neovagina with adequate depth. However, the impact of BMI on outcomes of sigmoid colon vaginoplasty remains unclear.</p><p><strong>Objective: </strong>To evaluate the effect of elevated BMI on short- and medium-term postoperative outcomes in patients undergoing sigmoid colon vaginoplasty.</p><p><strong>Design: </strong>Retrospective cohort study.</p><p><strong>Setting: </strong>Single-institution study conducted at a tertiary academic medical center.</p><p><strong>Patients: </strong>Transgender and nonbinary patients who underwent sigmoid colon vaginoplasty between December 2020 and February 2024 with a minimum of 6 months postoperative follow-up. Patients were stratified into BMI ≥35 (obese) and BMI <35 (nonobese) cohorts.</p><p><strong>Interventions: </strong>Sigmoid colon vaginoplasty, performed by senior surgeons using robotic-assisted techniques. No additional interventions were tested.</p><p><strong>Main outcome measures: </strong>Operative time, length of stay, time to mobilization and dilation, short- and medium-term postoperative complications, reoperation, and revision rates.</p><p><strong>Results: </strong>A total of 119 patients (median age 33 years) were included, with 29 (24.4%) classified as obese. Obese patients had significantly higher BMI (37.3 vs 26.7, p < 0.001) and were more likely to have ASA III classification (20.7% vs 4.4%, p = 0.006). There were no significant differences in operative time (203 vs 188.5 min, p = 0.277), hospital stay, or mobilization. Patients with BMI ≥35 had higher but nonsignificant rates of short-term complications (24.1% vs 15.6%, p = 0.292), including bowel injury and dehiscence. Medium-term complications, such as vaginal prolapse, stenosis, reoperation, and revision vaginoplasty, were similar between groups.</p><p><strong>Limitations: </strong>Single-center retrospective design with a limited obese patient sample size and absence of long-term functional outcomes.</p><p><strong>Conclusions: </strong>Although differences were not statistically significant, patients with BMI ≥35 demonstrated higher complication rates, suggesting a potential trend that warrants further investigation. Sigmoid colon vaginoplasty appears safe in appropriately selected patients across BMI categories, but individualized risk assessment and close perioperative monitoring are advised, particularly in patients with higher BMIs. See Video Abstract .</p><p><strong>Ms all del lmite resultados tras la vaginoplastia sigmoidea en pacientes con un imc: </strong>ANTECEDENTES:La vaginoplastia con colon sigmoide es un procedimiento de reafirmación de género que ofrece una neovagina autolubricante con la profundidad adecuada. Sin embargo, el impacto del IMC en los resultados de la vaginoplastia con colon sigmoide sigue sin estar claro.OBJETIVO:Evaluar el efecto del IMC elevado en los resultados posoperatorios a corto y
背景:乙状结肠阴道成形术是一种性别确认手术,提供具有足够深度的自润滑新阴道。然而,BMI对乙状结肠阴道成形术结果的影响尚不清楚。目的:探讨BMI升高对乙状结肠阴道成形术患者术后中短期预后的影响。设计:回顾性队列研究。环境:在三级学术医疗中心进行的单机构研究。患者:在2020年12月至2024年2月期间接受乙状结肠阴道成形术的变性和非二元患者,术后随访至少6个月。患者被分为BMI≥35 kg/m2(肥胖)和BMI干预:由高级外科医生使用机器人辅助技术进行乙状结肠阴道成形术。没有测试其他干预措施。主要观察指标:手术时间、住院时间、活动和扩张时间、术后中短期并发症、再手术和翻修率。结果:共纳入119例患者(中位年龄33岁),其中29例(24.4%)为肥胖。肥胖患者的BMI (37.3 vs. 26.7, p < 0.001)和ASA III级(20.7% vs. 4.4%, p = 0.006)明显高于肥胖患者。两组在手术时间(203 vs. 188.5 min, p = 0.277)、住院时间和活动量方面均无显著差异。BMI≥35的患者有更高但不显著的短期并发症发生率(24.1%比15.6%,p = 0.292),包括肠损伤和裂孔。中期并发症,如阴道脱垂、狭窄、再手术和阴道翻修成形术,两组间相似。局限性:单中心回顾性设计,肥胖患者样本量有限,缺乏长期功能结果。结论:虽然差异无统计学意义,但BMI≥35的患者并发症发生率较高,提示有进一步研究的潜在趋势。乙状结肠阴道成形术在适当选择的不同BMI类别的患者中是安全的,但建议个体化风险评估和严密的围手术期监测,特别是在高BMI个体中。参见视频摘要。
{"title":"Beyond the Cutoff: Outcomes After Sigmoid Colon Vaginoplasty in Patients With BMI ≥35.","authors":"Isabel Snee, Sami Ferdousian, Rachel N Rohrich, Ryan P Lin, Christian X Lava, Anusha Singh, Ilana G Margulies, Kenneth L Fan, David M Lisle, Gabriel A Del Corral","doi":"10.1097/DCR.0000000000003994","DOIUrl":"10.1097/DCR.0000000000003994","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Sigmoid colon vaginoplasty is a gender-affirming procedure offering a self-lubricating neovagina with adequate depth. However, the impact of BMI on outcomes of sigmoid colon vaginoplasty remains unclear.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To evaluate the effect of elevated BMI on short- and medium-term postoperative outcomes in patients undergoing sigmoid colon vaginoplasty.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Design: &lt;/strong&gt;Retrospective cohort study.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Setting: &lt;/strong&gt;Single-institution study conducted at a tertiary academic medical center.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Patients: &lt;/strong&gt;Transgender and nonbinary patients who underwent sigmoid colon vaginoplasty between December 2020 and February 2024 with a minimum of 6 months postoperative follow-up. Patients were stratified into BMI ≥35 (obese) and BMI &lt;35 (nonobese) cohorts.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Interventions: &lt;/strong&gt;Sigmoid colon vaginoplasty, performed by senior surgeons using robotic-assisted techniques. No additional interventions were tested.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Main outcome measures: &lt;/strong&gt;Operative time, length of stay, time to mobilization and dilation, short- and medium-term postoperative complications, reoperation, and revision rates.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 119 patients (median age 33 years) were included, with 29 (24.4%) classified as obese. Obese patients had significantly higher BMI (37.3 vs 26.7, p &lt; 0.001) and were more likely to have ASA III classification (20.7% vs 4.4%, p = 0.006). There were no significant differences in operative time (203 vs 188.5 min, p = 0.277), hospital stay, or mobilization. Patients with BMI ≥35 had higher but nonsignificant rates of short-term complications (24.1% vs 15.6%, p = 0.292), including bowel injury and dehiscence. Medium-term complications, such as vaginal prolapse, stenosis, reoperation, and revision vaginoplasty, were similar between groups.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Limitations: &lt;/strong&gt;Single-center retrospective design with a limited obese patient sample size and absence of long-term functional outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Although differences were not statistically significant, patients with BMI ≥35 demonstrated higher complication rates, suggesting a potential trend that warrants further investigation. Sigmoid colon vaginoplasty appears safe in appropriately selected patients across BMI categories, but individualized risk assessment and close perioperative monitoring are advised, particularly in patients with higher BMIs. See Video Abstract .&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Ms all del lmite resultados tras la vaginoplastia sigmoidea en pacientes con un imc: &lt;/strong&gt;ANTECEDENTES:La vaginoplastia con colon sigmoide es un procedimiento de reafirmación de género que ofrece una neovagina autolubricante con la profundidad adecuada. Sin embargo, el impacto del IMC en los resultados de la vaginoplastia con colon sigmoide sigue sin estar claro.OBJETIVO:Evaluar el efecto del IMC elevado en los resultados posoperatorios a corto y ","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"87-94"},"PeriodicalIF":3.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145354144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Scenarios in Coloproctology: Colovaginoplasty With Sigmoid Flap After Rectoneovaginal Fistula in Transgender Patient. 直肠直肠外科的新进展:跨性别患者直肠阴道瘘后乙状结肠瓣阴道成形术。
IF 3.7 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2026-01-01 Epub Date: 2025-10-29 DOI: 10.1097/DCR.0000000000003880
Noelia Ibáñez, Quiteria Hernández, Jesús Abrisqueta, Israel Abellán, Mariano J Montoya, Gines García Buendía, Juan de Dios García, Pablo Ramírez
{"title":"New Scenarios in Coloproctology: Colovaginoplasty With Sigmoid Flap After Rectoneovaginal Fistula in Transgender Patient.","authors":"Noelia Ibáñez, Quiteria Hernández, Jesús Abrisqueta, Israel Abellán, Mariano J Montoya, Gines García Buendía, Juan de Dios García, Pablo Ramírez","doi":"10.1097/DCR.0000000000003880","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003880","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":"69 1","pages":"100-101"},"PeriodicalIF":3.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145809793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Sarcopenic Obesity on Postoperative Outcomes in Patients With IBD After Bowel Resection Surgery: A Retrospective Cohort Study. 肌肉减少性肥胖对炎性肠病患者肠切除术后预后的影响:一项回顾性队列研究
IF 3.7 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2026-01-01 Epub Date: 2025-11-04 DOI: 10.1097/DCR.0000000000004013
Yihan Xu, Tianrun Song, Lei Cao, Yi Li, Weiming Zhu, Jianfeng Gong, Zekuan Xu, Zhen Guo
<p><strong>Background: </strong>Sarcopenic obesity is associated with poor prognosis in many diseases, but its role in postoperative complications in IBD remains unclear.</p><p><strong>Objective: </strong>To investigate the association of sarcopenic obesity with major complication risk in patients with IBD who underwent bowel resection surgery.</p><p><strong>Design: </strong>Retrospective cohort analysis.</p><p><strong>Settings: </strong>Single tertiary care center.</p><p><strong>Patients: </strong>Patients with IBD who underwent abdominal surgery between January 2019 and December 2023 were included. Skeletal muscle mass and visceral adipose tissue were evaluated by preoperative CT at the level of the third lumbar vertebra (L3) to define sarcopenia and obesity. Patients were classified into 1 of 4 body composition groups according to the presence or absence of sarcopenia and obesity.</p><p><strong>Main outcome measures: </strong>Major postoperative complications within 30 days.</p><p><strong>Results: </strong>A total of 274 patients were included. Body composition was classified as sarcopenic nonobesity in 121 patients (44.2%), nonsarcopenic nonobesity in 85 patients (31.0%), nonsarcopenic obesity in 34 patients (12.4%), and sarcopenic obesity in 34 patients (12.4%). A similar percentage of minor complications occurred in the 4 groups. However, patients with sarcopenic obesity had a significantly greater rate of major complications (52.9%) than those with nonsarcopenic obesity (28.1%), sarcopenic nonobesity (20.6%), and nonsarcopenic nonobesity (8.2%, p < 0.001). Multivariate analysis identified sarcopenic obesity as a significant risk factor for major complications (OR 14.10; 95% CI, 3.02-65.8; p < 0.001) in patients with IBD undergoing bowel resection surgery. In addition, current smokers, a change in the level of C-reactive protein (postoperative day 5 - postoperative day 1) >0 mg/L, preoperative enteral nutrition therapy, and a preoperative albumin level >35 g/L were also confirmed as independent risk factors for major complications. Moreover, nomogram models were constructed for patients with Crohn's disease and patients with ulcerative colitis to better predict the risk of major complications.</p><p><strong>Limitations: </strong>This was a single-center retrospective study.</p><p><strong>Conclusions: </strong>Sarcopenic obesity was identified as a significant risk factor for major complications in patients with IBD undergoing bowel resection surgery. See Video Abstract .</p><p><strong>Impacto de la obesidad sarcopnica en los resultados posoperatorios de pacientes con enfermedad inflamatoria intestinal sometidos a ciruga de reseccin intestinal un estudio de cohorte retrospectivo: </strong>ANTECEDENTES:La obesidad sarcopénica se asocia con un mal pronóstico en muchas enfermedades, pero su papel en las complicaciones posoperatorias en la EII sigue sin estar claro.OBJETIVO:Investigar la asociación de la obesidad sarcopénica con el riesgo de com
背景:肌少性肥胖与许多疾病的不良预后相关,但其在IBD术后并发症中的作用尚不清楚。目的:探讨行肠切除术的IBD患者肌肉减少型肥胖与主要并发症风险的关系。设计:对2019年1月至2023年12月进行腹部手术的IBD患者进行回顾性队列分析。设置:单一三级保健中心。患者:通过术前第三腰椎(L3)水平的计算机断层扫描评估骨骼肌质量和内脏脂肪组织,以确定肌肉减少症和肥胖。根据有无肌肉减少症和肥胖,将患者分为4个体成分组中的1个。主要观察指标:术后30天主要并发症。结果:121例(44.2%)患者的身体组成分为肌肉减少-非肥胖,85例(31.0%)患者为非肌肉减少-非肥胖,34例(12.4%)患者为非肌肉减少-肥胖,34例(12.4%)患者为肌肉减少-肥胖。四组患者发生轻微并发症的比例相似。然而,肌肉减少型肥胖患者的主要并发症发生率(52.9%)明显高于非肌肉减少型肥胖患者(28.1%)、肌肉减少型非肥胖患者(20.6%)和非肌肉减少型非肥胖患者(8.2%,p < 0.001)。多因素分析发现,肌肉减少型肥胖是肠切除手术中IBD患者主要并发症的重要危险因素(OR, 14.10; 95% CI: 3.02-65.8, p < 0.001)。此外,目前吸烟者、△CRP(术后第5天-术后第1天)>0 mg/L、术前肠内营养治疗、术前Alb >35 g/L也被确认为主要并发症的独立因素。并分别构建CD和UC患者的nomogram模型,更好地预测主要并发症的发生风险。局限性:这是一项单中心回顾性研究。结论:肌少性肥胖被认为是IBD患者行肠切除手术主要并发症的重要危险因素。参见视频摘要。
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引用次数: 0
Right Colectomy Using Single-Port Robotic Platform. 利用单孔机器人平台进行右结肠切除术。
IF 3.7 2区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2026-01-01 Epub Date: 2025-10-06 DOI: 10.1097/DCR.0000000000003791
Fred C Kobylarz, Salvatore A Parascandola, Aimal Khan
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引用次数: 0
期刊
Diseases of the Colon & Rectum
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