Oladunni Oluwoye, Megan Puzia, Bryony Stokes, Elizabeth R. Fraser, Sheldon Stokes, Khairul Siddiqi, John M. Roll
Background
Studies have reported high rates of alcohol and cannabis use and poor outcomes associated with substance use among individuals enrolled in coordinated specialty care (CSC) for first episode psychosis (FEP). Given these findings, substance use interventions within CSC would likely benefit individuals with FEP. This proof-of-concept study tested a standard and family-based contingency management (CM) model within CSC.
Method
Fourteen participants were recruited from a CSC programme for FEP to participate in standard CM and family-based CM for substance use intervention developed and refined by an advisory board comprised of key stakeholders. The CM intervention consisted of personalising CM by allocating participants to receive standard CM or family-based CM. Participants submitted urinalysis samples to assess alcohol and cannabis use across a 2-week warm-up phase, followed by a 12-week active CM phase.
Results
Approximately 60% of participants identified as an ethnoracial minority. At baseline, 78% of participants reported cannabis as the primary target substance and 64% opted into the family-based model. Eighty-four percent of urinalysis samples were submitted and 64% completed ≥ 8 weeks. Compared to baseline, substance use significantly decreased during the active CM phase (p < 0.003).
Conclusions
This pilot study suggests that a flexible CM model to address alcohol and cannabis, with the option for family involvement, may be feasible in CSC settings and increase abstinence among young adults with FEP. A high percentage of urinalysis samples were submitted, although most participants completed less than 12 weeks of CM. While findings show promise, additional modifications and pilot studies are needed to further optimise CM for CSC prior to conducting a larger efficacy trial.
{"title":"Proof-of-Concept Pilot Study on the Integration of a Contingency Management Model to Address Substance Use Among Individuals Enrolled in Early Intervention Programs for Psychosis","authors":"Oladunni Oluwoye, Megan Puzia, Bryony Stokes, Elizabeth R. Fraser, Sheldon Stokes, Khairul Siddiqi, John M. Roll","doi":"10.1111/eip.70037","DOIUrl":"https://doi.org/10.1111/eip.70037","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Studies have reported high rates of alcohol and cannabis use and poor outcomes associated with substance use among individuals enrolled in coordinated specialty care (CSC) for first episode psychosis (FEP). Given these findings, substance use interventions within CSC would likely benefit individuals with FEP. This proof-of-concept study tested a standard and family-based contingency management (CM) model within CSC.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Fourteen participants were recruited from a CSC programme for FEP to participate in standard CM and family-based CM for substance use intervention developed and refined by an advisory board comprised of key stakeholders. The CM intervention consisted of personalising CM by allocating participants to receive standard CM or family-based CM. Participants submitted urinalysis samples to assess alcohol and cannabis use across a 2-week warm-up phase, followed by a 12-week active CM phase.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Approximately 60% of participants identified as an ethnoracial minority. At baseline, 78% of participants reported cannabis as the primary target substance and 64% opted into the family-based model. Eighty-four percent of urinalysis samples were submitted and 64% completed ≥ 8 weeks. Compared to baseline, substance use significantly decreased during the active CM phase (<i>p</i> < 0.003).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This pilot study suggests that a flexible CM model to address alcohol and cannabis, with the option for family involvement, may be feasible in CSC settings and increase abstinence among young adults with FEP. A high percentage of urinalysis samples were submitted, although most participants completed less than 12 weeks of CM. While findings show promise, additional modifications and pilot studies are needed to further optimise CM for CSC prior to conducting a larger efficacy trial.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70037","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143835923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We aimed to identify if offspring of a parent with mood disorders presented cognitive deficits on 14 cognitive subtests while controlling for intellectual quotient, anxio-depressive symptoms, symptoms of attention deficit hyperactivity disorder (ADHD) or insomnia.
Methods
Using the Healthy Brain Network biobank, we identified 44 offspring of a parent with bipolar disorder (BD), 87 offspring of a parent with major depressive disorder (MDD) and 88 offspring of healthy parents. Analyses of variance (ANOVA) were performed to determine if groups differed on 14 subtests of the Wechsler Intelligence Scale for Children-5th Edition (WISC) and National Institutes of Health toolbox.
Results
Across all subtests, groups did not significantly differ. Only a subtle effect was found for male participants in which high-risk participants exhibited lower scores on the mental rotation subtest compared to the control group.
Conclusion
Overall, our results suggest intact cognition in young offspring of parents with a mood disorder.
{"title":"Brief Report: Intact Cognitive Functions in Children and Adolescents of Parents With Mood Disorders","authors":"Mélanie Boisvert, Jules R. Dugré, Stéphane Potvin","doi":"10.1111/eip.70042","DOIUrl":"https://doi.org/10.1111/eip.70042","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>We aimed to identify if offspring of a parent with mood disorders presented cognitive deficits on 14 cognitive subtests while controlling for intellectual quotient, anxio-depressive symptoms, symptoms of attention deficit hyperactivity disorder (ADHD) or insomnia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Using the Healthy Brain Network biobank, we identified 44 offspring of a parent with bipolar disorder (BD), 87 offspring of a parent with major depressive disorder (MDD) and 88 offspring of healthy parents. Analyses of variance (ANOVA) were performed to determine if groups differed on 14 subtests of the Wechsler Intelligence Scale for Children-5th Edition (WISC) and National Institutes of Health toolbox.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Across all subtests, groups did not significantly differ. Only a subtle effect was found for male participants in which high-risk participants exhibited lower scores on the mental rotation subtest compared to the control group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Overall, our results suggest intact cognition in young offspring of parents with a mood disorder.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70042","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143831455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christopher Jamil de Montgomery, Amanda Falah Rasmussen, Jakob Bergström, Heidi Taipale, Aemal Akhtar, Allan Krasnik, Marie Nørredam, Ellenor Mittendorfer-Rutz, Alexis E. Cullen
Introduction
The objective of this study was to examine group differences in healthcare contacts prior to a first diagnosis of non-affective psychotic disorders (NAPDs) comparing young refugees settled in Denmark and Sweden before turning 18 non-refugee migrants and native-born individuals.
Methods
Using nationwide register data, we identified all individuals aged 18–35 who received an NAPD diagnosis during 2006–2018. Healthcare contacts for other psychiatric disorders were categorised as inpatient, outpatient (grouped by discharge diagnosis) or dispensed antidepressant medication. Logistic regression was used in each country to compare contacts within 12 months prior to NAPD diagnosis, yielding odds ratios (OR) and corresponding 95% confidence intervals (CI), while standardised prevalence ratios (SPR), reported in percentages, were used to compare healthcare contact across countries.
Results
We included 11,679 individuals in Denmark and 11,088 in Sweden. The likelihood of prior contact of any type was lower in both countries for both refugees [Denmark: OR = 0.75(CI: 0.63, 0.90); Sweden: OR = 0.61(CI: 0.55, 0.68)] and non-refugee migrants [Denmark: OR = 0.78(CI: 0.64, 0.95); Sweden: OR = 0.55(CI: 0.49, 0.62)] compared with majority peers. The largest differences were observed for dispensed antidepressants in both countries [Denmark: ORrefugees = 0.58(CI: 0.47, 0.71); Sweden: ORrefugees = 0.52(CI: 0.45, 0.61)]. Outpatient contacts in particular were more common in Sweden than in Denmark across all groups [SIRrefugees = 151% (CI: 125, 180)].
Conclusion
Young refugees and non-refugee migrants in both Denmark and Sweden were less likely to have healthcare contact for other psychiatric disorders prior to NAPD onset than host populations. As healthcare contacts offer opportunities to identify treatment needs early, these groups may be vulnerable to delays in the pathway to treatment.
{"title":"Refugee Migration Background and Healthcare Contacts Prior to First-Episode Psychosis in Young Adults in Denmark and Sweden: Are Patterns Consistent Across Countries?","authors":"Christopher Jamil de Montgomery, Amanda Falah Rasmussen, Jakob Bergström, Heidi Taipale, Aemal Akhtar, Allan Krasnik, Marie Nørredam, Ellenor Mittendorfer-Rutz, Alexis E. Cullen","doi":"10.1111/eip.70039","DOIUrl":"https://doi.org/10.1111/eip.70039","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>The objective of this study was to examine group differences in healthcare contacts prior to a first diagnosis of non-affective psychotic disorders (NAPDs) comparing young refugees settled in Denmark and Sweden before turning 18 non-refugee migrants and native-born individuals.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Using nationwide register data, we identified all individuals aged 18–35 who received an NAPD diagnosis during 2006–2018. Healthcare contacts for other psychiatric disorders were categorised as inpatient, outpatient (grouped by discharge diagnosis) or dispensed antidepressant medication. Logistic regression was used in each country to compare contacts within 12 months prior to NAPD diagnosis, yielding odds ratios (OR) and corresponding 95% confidence intervals (CI), while standardised prevalence ratios (SPR), reported in percentages, were used to compare healthcare contact across countries.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We included 11,679 individuals in Denmark and 11,088 in Sweden. The likelihood of prior contact of any type was lower in both countries for both refugees [Denmark: OR = 0.75(CI: 0.63, 0.90); Sweden: OR = 0.61(CI: 0.55, 0.68)] and non-refugee migrants [Denmark: OR = 0.78(CI: 0.64, 0.95); Sweden: OR = 0.55(CI: 0.49, 0.62)] compared with majority peers. The largest differences were observed for dispensed antidepressants in both countries [Denmark: OR<sub>refugees</sub> = 0.58(CI: 0.47, 0.71); Sweden: OR<sub>refugees</sub> = 0.52(CI: 0.45, 0.61)]. Outpatient contacts in particular were more common in Sweden than in Denmark across all groups [SIR<sub>refugees</sub> = 151% (CI: 125, 180)].</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Young refugees and non-refugee migrants in both Denmark and Sweden were less likely to have healthcare contact for other psychiatric disorders prior to NAPD onset than host populations. As healthcare contacts offer opportunities to identify treatment needs early, these groups may be vulnerable to delays in the pathway to treatment.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143818422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Schizophrenia presents significant challenges, with cognitive dysfunction being a hallmark feature affecting daily functioning.
Aims
The study explores the impact of metacognitive training (MCT) on cognitive function in schizophrenia patients.
Methods
A systematic review and meta-analysis encompassed 21 studies identified through databases and manual searches. Inclusion criteria focused on MCT interventions, controlled experimental designs and cognitive outcome measures. Data synthesis and meta-analysis followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
Results
The meta-analysis results revealed a significant effect of MCT on Cognitive Biases Questionnaire(CBQ)-catastrophizing (JTC) (No. studies = 3, SMD = −0.61, 95% CI: −0.98, −0.25; I2 = 0.0%, p = 0.92) and CBQ-emotional reasoning(ER) (No. studies = 2, SMD = −0.50, 95% CI: −0.82, −0.18; I2 = 0.0%, p = 0.92), Positive and Negative Syndrome Scale (PANSS)-positive(P) (No. studies = 14, SMD = −0.52, 95% CI: −0.68, −0.35; I2 = 0.0%, p = 0.62), PANSS-negative(N) (No. studies = 8, SMD = −0.21, 95% CI: −0.42, −0.00; I2 = 0.0%, p = 0.94) and PANSS-total(T) (No. studies = 8, SMD = −0.42, 95% CI: −0.68, −0.16; I2 = 22.30%, p = 0.25) among schizophrenia patients. However, we found no significant impact of MCT treatment on CBQ-total(T), CBQ- intentionalizing (I), CBQ-catastrophizing(C), CBQ-dichotomous thinking(DT), Beck Cognitive Insight Scale(BCIS)-self-reflectiveness(SR), BCIS-self-certainty(SC), BCIS-composite index(CI) and PANSS-general(G) scores.
Conclusion
MCT demonstrates a positive impact on cognitive biases and symptom severity in schizophrenia patients. These results advocate for innovative, personalised interventions to complement traditional approaches in schizophrenia management.
Oliver Ardill-Young, Scott Teasdale, Paul Rich, Antonia Ottavio, Benjamin Lueck, Louise Treen, Michael Hodgins, Jackie Curtis
Aims
Group interventions can be an appropriate care option for young people with mental ill-health, yet there is a lack of research on their implementation within real-world settings. This paper aimed to explore the feasibility and acceptability of group interventions and a Group Coordinator peer work role in a community mental health service and the perspectives of young people, carers and staff on implementation.
Methods
A retrospective chart audit of 121 referrals to group interventions from January 2022 to June 2023 was conducted. Education, demographic and administrative data were collected to explore feasibility and acceptability. Survey data from 44 young people who participated was also used to explore acceptability. Semi-structured interviews (8 young people, 7 carers and 11 staff) explored perspectives on implementation, mapping barriers and facilitators to domains of the Comprehensive Framework for Implementation Research.
Results
Referrals made before the young person was involved in mental health treatment (i.e., at the stage of assessment) were less likely to result in engagement in a group, suggesting limited feasibility as a standalone care option. Young people reported overall positive experiences of group interventions, though attrition rates and qualitative interviews indicate they are perceived as less acceptable than individual options. The Group Coordinator role was viewed by staff as key to sustainability, with multiple benefits.
Conclusions
The current paper contributes to the scant literature on the implementation of group interventions with several practical implications for service planning. Further studies are needed to examine the implementation in other contexts, explore within-treatment variables and incorporate clinical outcomes.
{"title":"Implementation of Transdiagnostic Psychosocial Group Interventions and a Novel Peer Work Role in a Community Youth Mental Health Setting","authors":"Oliver Ardill-Young, Scott Teasdale, Paul Rich, Antonia Ottavio, Benjamin Lueck, Louise Treen, Michael Hodgins, Jackie Curtis","doi":"10.1111/eip.70038","DOIUrl":"https://doi.org/10.1111/eip.70038","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>Group interventions can be an appropriate care option for young people with mental ill-health, yet there is a lack of research on their implementation within real-world settings. This paper aimed to explore the feasibility and acceptability of group interventions and a Group Coordinator peer work role in a community mental health service and the perspectives of young people, carers and staff on implementation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective chart audit of 121 referrals to group interventions from January 2022 to June 2023 was conducted. Education, demographic and administrative data were collected to explore feasibility and acceptability. Survey data from 44 young people who participated was also used to explore acceptability. Semi-structured interviews (8 young people, 7 carers and 11 staff) explored perspectives on implementation, mapping barriers and facilitators to domains of the Comprehensive Framework for Implementation Research.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Referrals made before the young person was involved in mental health treatment (i.e., at the stage of assessment) were less likely to result in engagement in a group, suggesting limited feasibility as a standalone care option. Young people reported overall positive experiences of group interventions, though attrition rates and qualitative interviews indicate they are perceived as less acceptable than individual options. The Group Coordinator role was viewed by staff as key to sustainability, with multiple benefits.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The current paper contributes to the scant literature on the implementation of group interventions with several practical implications for service planning. Further studies are needed to examine the implementation in other contexts, explore within-treatment variables and incorporate clinical outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70038","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143818423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ZhaoXuan Shang, ChunQing Fang, Xiao E Lang, XiangYang Zhang
Background
Prior research has shown varying suicide attempt rates based on the age of onset in major depressive disorder (MDD) patients. However, there is a paucity of research on psychotic major depressive disorder (PMD) patients. This study aimed to assess the prevalence and correlates of suicide attempts in PMD patients stratified by age of onset.
Methods
Totally, 1718 first-episode drug-naïve MDD outpatients were recruited, divided into early-age onset (EAO) and middle-age onset (MAO) based on the first episode before age 45/after age 45. Clinical severity was assessed using the Hamilton Depression Rating Scale (HAMD), the Hamilton Anxiety Rating Scale (HAMA) and the Positive and Negative Syndrome Scale (PANSS) positive subscale. In addition, thyroid hormone and glucolipid metabolism indicators were measured.
Results
In EAO PMD patients, HAMA scale score and thyroid-stimulating hormone (TSH) levels were associated with suicide attempts. The area under the receiver operating characteristic curve (AUROC) was 0.892. In MAO PMD patients, TSH and diastolic blood pressure were associated with suicide attempts. The AUROC was 0.862.
Conclusion
This study demonstrates that the prevalence and correlates of suicide attempts vary among PMD patients with different ages of onset. Age of onset should be considered in the prevention and treatment of suicide attempts in patients with PMD.
{"title":"Prevalence and Correlates of Suicide Attempts in Chinese Outpatients With First-Episode and Drug-Naïve Psychotic Major Depressive Disorder at Different Ages of Onset","authors":"ZhaoXuan Shang, ChunQing Fang, Xiao E Lang, XiangYang Zhang","doi":"10.1111/eip.70036","DOIUrl":"https://doi.org/10.1111/eip.70036","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Prior research has shown varying suicide attempt rates based on the age of onset in major depressive disorder (MDD) patients. However, there is a paucity of research on psychotic major depressive disorder (PMD) patients. This study aimed to assess the prevalence and correlates of suicide attempts in PMD patients stratified by age of onset.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Totally, 1718 first-episode drug-naïve MDD outpatients were recruited, divided into early-age onset (EAO) and middle-age onset (MAO) based on the first episode before age 45/after age 45. Clinical severity was assessed using the Hamilton Depression Rating Scale (HAMD), the Hamilton Anxiety Rating Scale (HAMA) and the Positive and Negative Syndrome Scale (PANSS) positive subscale. In addition, thyroid hormone and glucolipid metabolism indicators were measured.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In EAO PMD patients, HAMA scale score and thyroid-stimulating hormone (TSH) levels were associated with suicide attempts. The area under the receiver operating characteristic curve (AUROC) was 0.892. In MAO PMD patients, TSH and diastolic blood pressure were associated with suicide attempts. The AUROC was 0.862.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study demonstrates that the prevalence and correlates of suicide attempts vary among PMD patients with different ages of onset. Age of onset should be considered in the prevention and treatment of suicide attempts in patients with PMD.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143793308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Monica E. Calkins, Megan Jumper, Arielle Ered, Fanghong Dong, Deepak K. Sarpal, Krista K. Baker, Donna J. Bencivengo, Russell L. Margolis, Robert W. Buchanan, Yasmine Boumaiz, Elizabeth Burris, Philip D. Campbell, K. N. Roy Chengappa, Catherine Conroy, Akinyi Cooke, Faith Dickerson, Nyasia Flowers, Mandy Fauble, Richard W. Goldberg, Alexander Harvin, Carolyn Howell, Christian Kelly, Julie Kreyenbuhl, Lan Li, Alicia Lucksted, Jill A. Marsteller, Alexander Moxam, Denise Namowicz, Swati Nayar, Jamie Oko, Jessie Riggs, Arunadevi Saravana, Rachel Scheinberg, William R. Smith, Richard States, Timur Suhail-Sindhu, Jerome Taylor, Crystal L. Vatza, Max Wolcott, Christian G. Kohler, Melanie E. Bennett
Aim
Connection Learning Healthcare System, one of the eight hubs of the National Institute of Mental Health funded Early Psychosis Intervention Network, supports uniform data collection, analysis, feedback and infrastructure development to promote a culture of continuous quality improvement across 25 Coordinated Specialty Care programs serving young people experiencing first episode psychosis and their families in Maryland and Pennsylvania. This first report describes the hub and its constituent programs, the approach for developing and implementing a hub-wide core assessment battery harmonised with the national battery, and preliminary program and participant characteristics.
Methods
Our hub developed and implemented a computerised core assessment battery, administered every 6 months and developed an integrated system for managing and analysing data.
Results
Between 1 January 2021 and 27 November 2023, 1059 participants were newly admitted to a hub program. The entire cohort (N = 1381) included newly admitted participants and those already in a program as of 1 January 2021. A total of 1245 complete assessment batteries were collected across all time points from 797 participants, with an additional 1920 partially completed batteries collected from 1319 participants. Data are uploaded to the National Data Coordinating Center, where our hub is the third largest data contributor. Descriptive information on programs and participants is provided.
Conclusions
As part of our learning healthcare system to improve clinical services and outcomes across two states, we have successfully implemented a standardised, computerised core assessment battery of essential characteristics and clinical outcomes. Successes, challenges and recommendations for data collection are provided. This paper will serve as a vital methodological resource for users of the unprecedented Early Psychosis Intervention Network national research database seeking to accelerate and improve early psychosis research.
{"title":"Connection Learning Healthcare System Hub of the Early Psychosis Intervention Network: Program and Participant Characteristics","authors":"Monica E. Calkins, Megan Jumper, Arielle Ered, Fanghong Dong, Deepak K. Sarpal, Krista K. Baker, Donna J. Bencivengo, Russell L. Margolis, Robert W. Buchanan, Yasmine Boumaiz, Elizabeth Burris, Philip D. Campbell, K. N. Roy Chengappa, Catherine Conroy, Akinyi Cooke, Faith Dickerson, Nyasia Flowers, Mandy Fauble, Richard W. Goldberg, Alexander Harvin, Carolyn Howell, Christian Kelly, Julie Kreyenbuhl, Lan Li, Alicia Lucksted, Jill A. Marsteller, Alexander Moxam, Denise Namowicz, Swati Nayar, Jamie Oko, Jessie Riggs, Arunadevi Saravana, Rachel Scheinberg, William R. Smith, Richard States, Timur Suhail-Sindhu, Jerome Taylor, Crystal L. Vatza, Max Wolcott, Christian G. Kohler, Melanie E. Bennett","doi":"10.1111/eip.70031","DOIUrl":"https://doi.org/10.1111/eip.70031","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Connection Learning Healthcare System, one of the eight hubs of the National Institute of Mental Health funded Early Psychosis Intervention Network, supports uniform data collection, analysis, feedback and infrastructure development to promote a culture of continuous quality improvement across 25 Coordinated Specialty Care programs serving young people experiencing first episode psychosis and their families in Maryland and Pennsylvania. This first report describes the hub and its constituent programs, the approach for developing and implementing a hub-wide core assessment battery harmonised with the national battery, and preliminary program and participant characteristics.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Our hub developed and implemented a computerised core assessment battery, administered every 6 months and developed an integrated system for managing and analysing data.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Between 1 January 2021 and 27 November 2023, 1059 participants were newly admitted to a hub program. The entire cohort (<i>N</i> = 1381) included newly admitted participants and those already in a program as of 1 January 2021. A total of 1245 complete assessment batteries were collected across all time points from 797 participants, with an additional 1920 partially completed batteries collected from 1319 participants. Data are uploaded to the National Data Coordinating Center, where our hub is the third largest data contributor. Descriptive information on programs and participants is provided.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>As part of our learning healthcare system to improve clinical services and outcomes across two states, we have successfully implemented a standardised, computerised core assessment battery of essential characteristics and clinical outcomes. Successes, challenges and recommendations for data collection are provided. This paper will serve as a vital methodological resource for users of the unprecedented Early Psychosis Intervention Network national research database seeking to accelerate and improve early psychosis research.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70031","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Scott B. Teasdale, Andrew Watkins, Oliver Ardill-Young, Eliza Draper, Philip B. Ward, Jackie Curtis
Objectives
To explore the oral health status and uptake of a free on-site professional check-up in young people with first-episode psychosis or with an at-risk mental state engaged with mental health services in Sydney, Australia.
Method
A retrospective analysis of a two-stage quality improvement project was undertaken. First, a 26-item survey was administered to young people engaged with the Early Psychosis and Youth (At-Risk Mental State) services. The survey was adapted from the NSW Teen Dental Survey 2010, modified to suit the needs of this population group. Survey responses were compared against national recommendations where possible. Second, people were offered a free, on-site, oral health check-up conducted by an oral health hygienist. Check-ups were scored into seven categories, ranging from ‘does not appear to require routine treatment’ to ‘needs urgent dental treatment’.
Results
Fifty young people completed the survey, of whom 70% met the Australian Dental Association recommendations for frequency of teeth brushing, 56% for brushing duration, and 16% for flossing. Fifty percent reported visiting a dentist at least once per year, and 30% reported that they do not visit the dentist. Twenty-seven people agreed to a dental check-up, with 16 participants attending, and of these, 44% were recommended for dental treatment or further assessment to determine treatment needs.
Conclusion
Young people with first-episode psychosis or with an at-risk mental state frequently report suboptimal oral health practices and may benefit from dental support to prevent the high rates of dental disease that occur in more advanced mental illness.
{"title":"Oral Health in Young People Accessing Services for Psychosis: A Retrospective Analysis","authors":"Scott B. Teasdale, Andrew Watkins, Oliver Ardill-Young, Eliza Draper, Philip B. Ward, Jackie Curtis","doi":"10.1111/eip.70030","DOIUrl":"https://doi.org/10.1111/eip.70030","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To explore the oral health status and uptake of a free on-site professional check-up in young people with first-episode psychosis or with an at-risk mental state engaged with mental health services in Sydney, Australia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>A retrospective analysis of a two-stage quality improvement project was undertaken. First, a 26-item survey was administered to young people engaged with the Early Psychosis and Youth (At-Risk Mental State) services. The survey was adapted from the NSW Teen Dental Survey 2010, modified to suit the needs of this population group. Survey responses were compared against national recommendations where possible. Second, people were offered a free, on-site, oral health check-up conducted by an oral health hygienist. Check-ups were scored into seven categories, ranging from ‘does not appear to require routine treatment’ to ‘needs urgent dental treatment’.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Fifty young people completed the survey, of whom 70% met the Australian Dental Association recommendations for frequency of teeth brushing, 56% for brushing duration, and 16% for flossing. Fifty percent reported visiting a dentist at least once per year, and 30% reported that they do not visit the dentist. Twenty-seven people agreed to a dental check-up, with 16 participants attending, and of these, 44% were recommended for dental treatment or further assessment to determine treatment needs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Young people with first-episode psychosis or with an at-risk mental state frequently report suboptimal oral health practices and may benefit from dental support to prevent the high rates of dental disease that occur in more advanced mental illness.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70030","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jahnese Hamilton, Akansha Singh, Chris Gibbs, Nicola A. Barclay, Lauren Birkett, Charleen Boyle, Toby Brandon, Robert Dudley, Jochen Einbeck, Victoria Larry, Jennifer Simpson, Guy Dodgson, Charles Fernyhough
Background
Individuals with an at risk mental state (ARMS) often experience hallucinatory-type experiences, which we refer to as unusual sensory experiences (USE). However, it is not known whether individuals want to know more about USE or discuss these in therapy. Our preferences study asked whether individuals who are referred into a treatment trial for USE in ARMS consider attention to USE important.
Methods
Ninety-four service users of ARMS services within two UK National Health Service (NHS) mental health trusts completed the study-specific, “Preferences for psychological therapy or support” questionnaire. Questions elicited preferences for target of therapeutic work and therapist approach. Analysis employs a repeated measures ANOVA with post hoc analysis of difference between preferences.
Results
Treatment preferences which help understand causes of USE and how to manage USE were the group priority above talking therapy generally or a focus on low mood or anxiety. Provision of medication was the lowest priority in treatment preference though it was important to some. Overall, working with a therapist to make sense of experiences was more important than having space to talk, new ideas for coping, or working collaboratively on goals.
Conclusions
Psychological intervention for individuals with at-risk mental state needs to include acceptable and credible psychoeducation on causes of USE and how to manage these.
{"title":"Preferences for Psychological Therapy or Support Within an ARMS Psychological Therapies Trial: The Importance of Targeted Intervention for Unusual Sensory Experiences","authors":"Jahnese Hamilton, Akansha Singh, Chris Gibbs, Nicola A. Barclay, Lauren Birkett, Charleen Boyle, Toby Brandon, Robert Dudley, Jochen Einbeck, Victoria Larry, Jennifer Simpson, Guy Dodgson, Charles Fernyhough","doi":"10.1111/eip.70035","DOIUrl":"https://doi.org/10.1111/eip.70035","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Individuals with an at risk mental state (ARMS) often experience hallucinatory-type experiences, which we refer to as unusual sensory experiences (USE). However, it is not known whether individuals want to know more about USE or discuss these in therapy. Our preferences study asked whether individuals who are referred into a treatment trial for USE in ARMS consider attention to USE important.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Ninety-four service users of ARMS services within two UK National Health Service (NHS) mental health trusts completed the study-specific, “Preferences for psychological therapy or support” questionnaire. Questions elicited preferences for target of therapeutic work and therapist approach. Analysis employs a repeated measures ANOVA with post hoc analysis of difference between preferences.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Treatment preferences which help understand <i>causes</i> of USE and how to <i>manage</i> USE were the group priority above talking therapy generally or a focus on low mood or anxiety. Provision of medication was the lowest priority in treatment preference though it was important to some. Overall, working with a therapist to make sense of experiences was more important than having space to talk, new ideas for coping, or working collaboratively on goals.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Psychological intervention for individuals with at-risk mental state needs to include acceptable and credible psychoeducation on causes of USE and how to manage these.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70035","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Young adults who experienced first episode psychosis (FEP) show impairments in social cognition, have smaller social circles, and experience less social support compared to their peers. While social cognition is important for social functioning, it is unclear whether these neurocognitive skills are related to social circle size or social support. It was examined whether participants with FEP and impairments in social cognition have smaller social circles and/or experience less social support.
Method
A cross-sectional study comparing 35 FEP participants in early recovery and 35 well-matched controls on measures of emotion perception, theory of mind (ToM), social perception, social circle size, and social support, and the relationship between social cognitive impairment, social circle size, and social support.
Results
Significant differences between the two groups were found only for ToM and not for emotion perception or social perception. FEP participants had a significantly smaller social circle size and perceived significantly less social support. Correlations between ToM and social circle size or social support were limited, with no significant differences when compared at the group level.
Conclusion
FEP participants and controls differ on social circle size and social support, while concerning social cognition, there was only a difference found on ToM between both groups. Questions are raised as to whether social cognition is related to social circle size or perceived social support in early recovery of FEP. While mechanisms influencing social circle size and social support need further research, it is important to continue to focus on social contact after FEP.
{"title":"The Relationship of Social Cognition on Social Circle Size and Social Support in Young Adults Recovering From First Episode Psychosis","authors":"Janneke van Houts, Barbara Montagne","doi":"10.1111/eip.70033","DOIUrl":"https://doi.org/10.1111/eip.70033","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Young adults who experienced first episode psychosis (FEP) show impairments in social cognition, have smaller social circles, and experience less social support compared to their peers. While social cognition is important for social functioning, it is unclear whether these neurocognitive skills are related to social circle size or social support. It was examined whether participants with FEP and impairments in social cognition have smaller social circles and/or experience less social support.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>A cross-sectional study comparing 35 FEP participants in early recovery and 35 well-matched controls on measures of emotion perception, theory of mind (ToM), social perception, social circle size, and social support, and the relationship between social cognitive impairment, social circle size, and social support.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Significant differences between the two groups were found only for ToM and not for emotion perception or social perception. FEP participants had a significantly smaller social circle size and perceived significantly less social support. Correlations between ToM and social circle size or social support were limited, with no significant differences when compared at the group level.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>FEP participants and controls differ on social circle size and social support, while concerning social cognition, there was only a difference found on ToM between both groups. Questions are raised as to whether social cognition is related to social circle size or perceived social support in early recovery of FEP. While mechanisms influencing social circle size and social support need further research, it is important to continue to focus on social contact after FEP.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 3","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143690162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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