Pub Date : 2019-07-01DOI: 10.32746/10.32746/ijmhns.2019.v2.i2.19
Huma Akbar, S. S., Shanthi B., Khadeja Bi, Jayaseelan R., N. M
BACKGROUND One third of Indians consume alcohol and there is an alarming annual increase in alcohol consumption. Majority of spouses of alcohol dependent males are also the primary care-takers of their husbands and are at risk of domestic violence. Marital dissatisfaction could reduce their involvement in getting their spouses treated for alcohol dependence. Our aim was to study the marital satisfaction among the spouses of patients with alcohol dependence. METHODOLOGY This study was conducted on spouses of male patients with alcohol dependence syndrome attending the psychiatry department of a tertiary care medical college hospital in Kanchipuram District in Tamilnadu. 200 consecutive male patients with alcohol dependence syndrome using the ICD 10 criteria were recruited. Severity of alcohol dependence was assessed using Short Alcohol Dependence Data (SADD). Marital satisfaction among the spouses was assessed using ENRICH Marital Satisfaction (EMS) Scale. Analysis of the data was done using Statistical Package for the Social Sciences (SPSS) version 22.0. RESULTS The mean age of alcohol dependent men and their spouses were 43.05±9.39 and 37.58±8.86 years respectively. Most of the spouses (83.5%) had done their primary education only and 50% were house-wives (unemployed). Majority of men earned between Rs.5000 to 10,000 and most of them were unskilled workers belonging to the lower socio-economic group in the rural areas. The mean SADD and EMS scores were 25.05 ± 8.891 and 31.76 ± 14.45 respectively. 74% of men in our study population were highly dependent on alcohol. Amongst the spouses of men with severe dependence 68.9% reported moderate and 28.3% reported low marital satisfaction. DISCUSSION and CONCLUSION Majority of alcohol dependent men suffered from severe dependence. An inverse relationship between marital satisfaction scores and severity of alcohol dependence was observed. Alcohol dependence and its severity was noted to have an adverse impact on marital satisfaction among spouses of the dependent patients.
{"title":"Marital Satisfaction Among Spouses of Male Patients with Alcohol Dependence Syndrome","authors":"Huma Akbar, S. S., Shanthi B., Khadeja Bi, Jayaseelan R., N. M","doi":"10.32746/10.32746/ijmhns.2019.v2.i2.19","DOIUrl":"https://doi.org/10.32746/10.32746/ijmhns.2019.v2.i2.19","url":null,"abstract":"BACKGROUND One third of Indians consume alcohol and there is an alarming annual increase in alcohol consumption. Majority of spouses of alcohol dependent males are also the primary care-takers of their husbands and are at risk of domestic violence. Marital dissatisfaction could reduce their involvement in getting their spouses treated for alcohol dependence. Our aim was to study the marital satisfaction among the spouses of patients with alcohol dependence. METHODOLOGY This study was conducted on spouses of male patients with alcohol dependence syndrome attending the psychiatry department of a tertiary care medical college hospital in Kanchipuram District in Tamilnadu. 200 consecutive male patients with alcohol dependence syndrome using the ICD 10 criteria were recruited. Severity of alcohol dependence was assessed using Short Alcohol Dependence Data (SADD). Marital satisfaction among the spouses was assessed using ENRICH Marital Satisfaction (EMS) Scale. Analysis of the data was done using Statistical Package for the Social Sciences (SPSS) version 22.0. RESULTS The mean age of alcohol dependent men and their spouses were 43.05±9.39 and 37.58±8.86 years respectively. Most of the spouses (83.5%) had done their primary education only and 50% were house-wives (unemployed). Majority of men earned between Rs.5000 to 10,000 and most of them were unskilled workers belonging to the lower socio-economic group in the rural areas. The mean SADD and EMS scores were 25.05 ± 8.891 and 31.76 ± 14.45 respectively. 74% of men in our study population were highly dependent on alcohol. Amongst the spouses of men with severe dependence 68.9% reported moderate and 28.3% reported low marital satisfaction. DISCUSSION and CONCLUSION Majority of alcohol dependent men suffered from severe dependence. An inverse relationship between marital satisfaction scores and severity of alcohol dependence was observed. Alcohol dependence and its severity was noted to have an adverse impact on marital satisfaction among spouses of the dependent patients.","PeriodicalId":113988,"journal":{"name":"INDIAN JOURNAL OF MENTAL HEALTH AND NEUROSCIENCES","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115693778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-01DOI: 10.32746/ijmhns.2019.v2.i2.25
S. Kantipudi, S. S., S. Vinoth, J. Menon
BACKGROUND: End of life care is increasingly becoming complex and protracted with the advances in critical care medicine.(1) Prolongation of life in critically ill elderly comes with multiple issues related to ethics, quality of life and autonomy of the patient, care giver burden, financial issues, and interplay of complex medical issues affecting the well being of the patient and the caregiver.(2) Palliative Psychiatry is increasingly being recognised as a major subspecialty when it comes to dealing with these situations.(3) There is a high incidence of delirium in end stage palliative care with a prevalence as high as 88%(4). Here we report a patient with multiple critical medical issues who suffered with severe and protracted delirium. He was brought in owing to unmanageable aggression and sleep wake cycle reversal which made the caregivers totally helpless. The complexities in his care and considering the family’s wishes for not having any invasive treatment procedures are being discussed.
{"title":"Delirium in an Unwell Elderly Patient - Psychiatrist in Palliative Care","authors":"S. Kantipudi, S. S., S. Vinoth, J. Menon","doi":"10.32746/ijmhns.2019.v2.i2.25","DOIUrl":"https://doi.org/10.32746/ijmhns.2019.v2.i2.25","url":null,"abstract":"BACKGROUND: End of life care is increasingly becoming complex and protracted with the advances in critical care medicine.(1) Prolongation of life in critically ill elderly comes with multiple issues related to ethics, quality of life and autonomy of the patient, care giver burden, financial issues, and interplay of complex medical issues affecting the well being of the patient and the caregiver.(2) Palliative Psychiatry is increasingly being recognised as a major subspecialty when it comes to dealing with these situations.(3) There is a high incidence of delirium in end stage palliative care with a prevalence as high as 88%(4). Here we report a patient with multiple critical medical issues who suffered with severe and protracted delirium. He was brought in owing to unmanageable aggression and sleep wake cycle reversal which made the caregivers totally helpless. The complexities in his care and considering the family’s wishes for not having any invasive treatment procedures are being discussed.","PeriodicalId":113988,"journal":{"name":"INDIAN JOURNAL OF MENTAL HEALTH AND NEUROSCIENCES","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125614227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-01DOI: 10.32746/ijmhns.2019.v2.i2.40
J. Menon, S. Kantipudi
There has been a plethora of discussions recently to bring about changes in the teaching of Psychiatry at the undergraduate level by various academicians. Much of it revolved around up-skilling teachers in Psychiatry, allocating more teaching hours for the subject in undergraduate curriculum, and moving to practice based learning.
{"title":"Crossroads in Post-Graduate Psychiatry Training in India","authors":"J. Menon, S. Kantipudi","doi":"10.32746/ijmhns.2019.v2.i2.40","DOIUrl":"https://doi.org/10.32746/ijmhns.2019.v2.i2.40","url":null,"abstract":"There has been a plethora of discussions recently to bring about changes in the teaching of Psychiatry at the undergraduate level by various academicians. Much of it revolved around up-skilling teachers in Psychiatry, allocating more teaching hours for the subject in undergraduate curriculum, and moving to practice based learning.","PeriodicalId":113988,"journal":{"name":"INDIAN JOURNAL OF MENTAL HEALTH AND NEUROSCIENCES","volume":"2018 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132007646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-01DOI: 10.32746/10.32746/ijmhns.2019.v2.i2.20
Ragaviveka Gopalan, C. Sangeetha, P. Ramakrishnan, V. Raghavan
BACKGROUND About 70% of mental disorders emerge in late childhood and young peo-ple bear the burden of these disorders throughout life. Yet, to date there has been com-paratively little research on mental health interventions for young people in India and not many attempts have been made to collate the existing literature. This systematic review aims to synthesize the available evidence on school- and community-based mental health interventions for young people in India. METHODS A range of major electronic databases were searched systematically, and the abstracts of relevant papers were independently examined for possible inclusion. Selected papers were read in full text and a standardized set of data items were extracted. RESULTS Four papers met inclusion criteria for the analysis; two studies of school-based interventions for adolescents and two studies evaluating out-of-school community interventions for youth were reviewed. The quality of evidence from the interventions in Indian school and community settings were poor. While two studies evidence the effectiveness of a school-based life skills programme and a community based multicomponent intervention designed to promote youth health, two other studies do not offer sufficient data. CONCLUSION The review findings indicate that the number of interventional studies conducted in India to address youth mental health issues are very limited. Hence, it is extremely difficult to ensure the feasibility and effectiveness of school and community-based interventions in India. Further research is warranted to establish whether interventions promoting youth mental health people can be implemented effectively in Indian settings with positive mental health outcomes. Given the possibility of a huge population of young people at-risk or experiencing mental disorders, evidence for the efficacy of youth mental health interventions is crucial.
{"title":"School and Community - based Youth Mental Health Intervention Studies in India: A Scoping Review","authors":"Ragaviveka Gopalan, C. Sangeetha, P. Ramakrishnan, V. Raghavan","doi":"10.32746/10.32746/ijmhns.2019.v2.i2.20","DOIUrl":"https://doi.org/10.32746/10.32746/ijmhns.2019.v2.i2.20","url":null,"abstract":"BACKGROUND About 70% of mental disorders emerge in late childhood and young peo-ple bear the burden of these disorders throughout life. Yet, to date there has been com-paratively little research on mental health interventions for young people in India and not many attempts have been made to collate the existing literature. This systematic review aims to synthesize the available evidence on school- and community-based mental health interventions for young people in India. METHODS A range of major electronic databases were searched systematically, and the abstracts of relevant papers were independently examined for possible inclusion. Selected papers were read in full text and a standardized set of data items were extracted. RESULTS Four papers met inclusion criteria for the analysis; two studies of school-based interventions for adolescents and two studies evaluating out-of-school community interventions for youth were reviewed. The quality of evidence from the interventions in Indian school and community settings were poor. While two studies evidence the effectiveness of a school-based life skills programme and a community based multicomponent intervention designed to promote youth health, two other studies do not offer sufficient data. CONCLUSION The review findings indicate that the number of interventional studies conducted in India to address youth mental health issues are very limited. Hence, it is extremely difficult to ensure the feasibility and effectiveness of school and community-based interventions in India. Further research is warranted to establish whether interventions promoting youth mental health people can be implemented effectively in Indian settings with positive mental health outcomes. Given the possibility of a huge population of young people at-risk or experiencing mental disorders, evidence for the efficacy of youth mental health interventions is crucial.","PeriodicalId":113988,"journal":{"name":"INDIAN JOURNAL OF MENTAL HEALTH AND NEUROSCIENCES","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123410923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-01DOI: 10.32746/10.32746/ijmhns.2019.v2.i2.27
N. M, K. P., S. S., S. R
BACKGROUND Autism spectrum disorder (ASD) is an neuro-developmental disorder. There is a paucity of epidemiological data on ASD in India. This study is an attempt to understand the socio demographic and clinical characteristics of the individuals with ASD. METHODS The case records were perused to extract the datas. RESULTS The study revealed that two third of individuals with ASD also have Intellectual Disability, more than half the mothers of individuals with ASD did not breastfeed beyond 12 months, about one third of individuals with ASD have not availed any kind of services. It takes arounds 6 years of age for the parents/ individuals with ASD to seek treatment help. CONCLUSION Understanding the profile is essential for better treatment planning.
{"title":"The Socio-Demographic and Clinical Profile of Individuals with Autism Spectrum Disorder in a Tertiary Care Teaching Hospital in South India","authors":"N. M, K. P., S. S., S. R","doi":"10.32746/10.32746/ijmhns.2019.v2.i2.27","DOIUrl":"https://doi.org/10.32746/10.32746/ijmhns.2019.v2.i2.27","url":null,"abstract":"BACKGROUND Autism spectrum disorder (ASD) is an neuro-developmental disorder. There is a paucity of epidemiological data on ASD in India. This study is an attempt to understand the socio demographic and clinical characteristics of the individuals with ASD. METHODS The case records were perused to extract the datas. RESULTS The study revealed that two third of individuals with ASD also have Intellectual Disability, more than half the mothers of individuals with ASD did not breastfeed beyond 12 months, about one third of individuals with ASD have not availed any kind of services. It takes arounds 6 years of age for the parents/ individuals with ASD to seek treatment help. CONCLUSION Understanding the profile is essential for better treatment planning.","PeriodicalId":113988,"journal":{"name":"INDIAN JOURNAL OF MENTAL HEALTH AND NEUROSCIENCES","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132840532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-28DOI: 10.32746/ijmhns.2019.v2.i1.15
S. Kantipudi, Sushma Vishwanathan, Kannan G K, J. Menon, Sathianathan N
Background: Maternal depression is associated with a number of adverse maternal outcomes such as preterm birth, maternal dysfunction, maternal suicide and perinatal outcomes such as low birth weight, lower rates of breastfeeding, increase in diarrheal disease, hospitalisations, poor emotional, social development, lower academic achievements in adolescence and future mental health problems for the children of the mothers. Maternal depression has rightly been identified as a priority mental health condition and large scale community interventions in low and middle income countries (including India) have been shown in RCTs to be effective in not only improving maternal depression but also improve the perinatal outcomes. Given the scale, severity of the problem and strength of evidence available for effective interventions in the Indian context, there is a great opportunity for implementation research in this area. As a first step there is a need to understand the prevalence of the problem and associated risk factors in our context. Aim: Aim of this study to understand the prevalence of maternal depression and associated risk factors among antenatal mothers attending Sri Ramachandra Medical College (SRMC) Obstetrics outpatient department. Methods: A cross-sectional design will be employed for determining the prevalence, while a case control framework will be used for the risk factor analysis. Antenatal mothers will be startified according to the trimester of the pregnancy. Semi-structured socio demographic proforma; Patient Health Questionnaire (PHQ-9 Tamil version), Generalised Anxiety Scale (Tamil Version) and Brief COPE (Tamil version) questionnaire will be administered for antenatal mothers who offer informed consent. Those who score above 10 points on the PHQ scale will be interviewed using the MINI diagnostic interview schedule for clarifying diagnosis. Those who are diagnosed with depression will be referred to the SRMC psychiatry department for treatment & follow up. Analysis: Statistical analysis is to be done using computer software, to assess the prevalence of antenatal depression and the associated risk factors. Descriptive statistics will be used to describe the sample. Mean, standard deviation and range will be employed to describe continuous variables, while frequency distributions will obtained for categorical variables. The chi square and fisher’s exact tests will be used to assess the significance of associations between categorical variables. Multivariate analysis will be performed using stepwise backward logistic regression models
{"title":"A protocol of a cross sectional study to assess depression in antenatal mothers","authors":"S. Kantipudi, Sushma Vishwanathan, Kannan G K, J. Menon, Sathianathan N","doi":"10.32746/ijmhns.2019.v2.i1.15","DOIUrl":"https://doi.org/10.32746/ijmhns.2019.v2.i1.15","url":null,"abstract":"Background: Maternal depression is associated with a number of adverse maternal outcomes such as preterm birth, maternal dysfunction, maternal suicide and perinatal outcomes such as low birth weight, lower rates of breastfeeding, increase in diarrheal disease, hospitalisations, poor emotional, social development, lower academic achievements in adolescence and future mental health problems for the children of the mothers. Maternal depression has rightly been identified as a priority mental health condition and large scale community interventions in low and middle income countries (including India) have been shown in RCTs to be effective in not only improving maternal depression but also improve the perinatal outcomes. Given the scale, severity of the problem and strength of evidence available for effective interventions in the Indian context, there is a great opportunity for implementation research in this area. As a first step there is a need to understand the prevalence of the problem and associated risk factors in our context. Aim: Aim of this study to understand the prevalence of maternal depression and associated risk factors among antenatal mothers attending Sri Ramachandra Medical College (SRMC) Obstetrics outpatient department. Methods: A cross-sectional design will be employed for determining the prevalence, while a case control framework will be used for the risk factor analysis. Antenatal mothers will be startified according to the trimester of the pregnancy. Semi-structured socio demographic proforma; Patient Health Questionnaire (PHQ-9 Tamil version), Generalised Anxiety Scale (Tamil Version) and Brief COPE (Tamil version) questionnaire will be administered for antenatal mothers who offer informed consent. Those who score above 10 points on the PHQ scale will be interviewed using the MINI diagnostic interview schedule for clarifying diagnosis. Those who are diagnosed with depression will be referred to the SRMC psychiatry department for treatment & follow up. Analysis: Statistical analysis is to be done using computer software, to assess the prevalence of antenatal depression and the associated risk factors. Descriptive statistics will be used to describe the sample. Mean, standard deviation and range will be employed to describe continuous variables, while frequency distributions will obtained for categorical variables. The chi square and fisher’s exact tests will be used to assess the significance of associations between categorical variables. Multivariate analysis will be performed using stepwise backward logistic regression models","PeriodicalId":113988,"journal":{"name":"INDIAN JOURNAL OF MENTAL HEALTH AND NEUROSCIENCES","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122743325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-28DOI: 10.32746/ijmhns.2019.v2.i1.17
Kannan G K
Autism is a major pervasive developmental disorder with lifelong impact on an individual. Early intervention plays an improtant role in ameliorating and reversing the course and outcome of the disorder. There is a huge gap between the need for providing effective culturally appropriate evidence based practices in the community and actual provision of care.
{"title":"Evidence based interventions in ASD : Bridging the gap between research and evidence","authors":"Kannan G K","doi":"10.32746/ijmhns.2019.v2.i1.17","DOIUrl":"https://doi.org/10.32746/ijmhns.2019.v2.i1.17","url":null,"abstract":"Autism is a major pervasive developmental disorder with lifelong impact on an individual. Early intervention plays an improtant role in ameliorating and reversing the course and outcome of the disorder. There is a huge gap between the need for providing effective culturally appropriate evidence based practices in the community and actual provision of care.","PeriodicalId":113988,"journal":{"name":"INDIAN JOURNAL OF MENTAL HEALTH AND NEUROSCIENCES","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133953089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-28DOI: 10.32746/ijmhns.2019.v2.i1.12
Soumya Rs, S. J. Daniel, M. Meenakshisundaram
Neuropsychiatric manifestations are common and occur in around 14-80% of patients with SLE. No particular neurologic or psychiatric manifestation is characteristic of SLE and the form and pattern of neuropsychiatric symptoms vary significantly. The American College of Rheumatology (ACR) Nomenclature provides case definition for 19 neuropsychiatric syndromes seen in SLE. However, these case definitions were not found to be effective in differentiating neuropsychiatric SLE (NPSLE) patients from those with neuropsychiatric manifestations not associated with SLE.Here we present a case of mania in a patient with SLE and discuss the differential diagnosis of neuropsychiatric manifestations of SLE and primary mood disorder. Symptoms of neuropsychiatric SLE vary significantly and psychiatric disturbances in a patient with SLE is a diagnosis of exclusion where other possibilities have to be considered including an independent comorbid psychiatric disorder. This case highlights the difficulty in the diagnostic process and the need for more studies on the differences between primary psychiatric disorders and neuropsychiatric SLE.
{"title":"Mania in an individual with Systemic Lupus Erythematosus – A case report","authors":"Soumya Rs, S. J. Daniel, M. Meenakshisundaram","doi":"10.32746/ijmhns.2019.v2.i1.12","DOIUrl":"https://doi.org/10.32746/ijmhns.2019.v2.i1.12","url":null,"abstract":"Neuropsychiatric manifestations are common and occur in around 14-80% of patients with SLE. No particular neurologic or psychiatric manifestation is characteristic of SLE and the form and pattern of neuropsychiatric symptoms vary significantly. The American College of Rheumatology (ACR) Nomenclature provides case definition for 19 neuropsychiatric syndromes seen in SLE. However, these case definitions were not found to be effective in differentiating neuropsychiatric SLE (NPSLE) patients from those with neuropsychiatric manifestations not associated with SLE.Here we present a case of mania in a patient with SLE and discuss the differential diagnosis of neuropsychiatric manifestations of SLE and primary mood disorder. Symptoms of neuropsychiatric SLE vary significantly and psychiatric disturbances in a patient with SLE is a diagnosis of exclusion where other possibilities have to be considered including an independent comorbid psychiatric disorder. This case highlights the difficulty in the diagnostic process and the need for more studies on the differences between primary psychiatric disorders and neuropsychiatric SLE.","PeriodicalId":113988,"journal":{"name":"INDIAN JOURNAL OF MENTAL HEALTH AND NEUROSCIENCES","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126217515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-27DOI: 10.32746/ijmhns.2019.v2.i1.14
Antra Chandan, V. Raghavan
The use of electroconvulsive therapy (ECT) in various neuropsychiatric disorders has been well accepted. ECT has been proven to be safe and effective in adolescents and in old age. However, only a handful of literature is available on its effectiveness in first episode psychosis (FEP). In this case series, individuals with FEP who received ECT in their 1st month of treatment for various indications were described. During follow-up, subjects showed considerable improvement in their psychopathology and functional outcomes. None of them had any adverse events during or after ECT sessions. Thus, the present case series highlights the usefulness and safety of early use of ECT in individuals with first episode psychosis and its effectiveness in reducing the acute symptoms leading to remission and better outcomes.
{"title":"Early use of electroconvulsive therapy in individuals with first episode psychosis: A case series","authors":"Antra Chandan, V. Raghavan","doi":"10.32746/ijmhns.2019.v2.i1.14","DOIUrl":"https://doi.org/10.32746/ijmhns.2019.v2.i1.14","url":null,"abstract":"The use of electroconvulsive therapy (ECT) in various neuropsychiatric disorders has been well accepted. ECT has been proven to be safe and effective in adolescents and in old age. However, only a handful of literature is available on its effectiveness in first episode psychosis (FEP). In this case series, individuals with FEP who received ECT in their 1st month of treatment for various indications were described. During follow-up, subjects showed considerable improvement in their psychopathology and functional outcomes. None of them had any adverse events during or after ECT sessions. Thus, the present case series highlights the usefulness and safety of early use of ECT in individuals with first episode psychosis and its effectiveness in reducing the acute symptoms leading to remission and better outcomes.","PeriodicalId":113988,"journal":{"name":"INDIAN JOURNAL OF MENTAL HEALTH AND NEUROSCIENCES","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131408980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-27DOI: 10.32746/ijmhns.2019.v2.i1.13
Nupur Mahatme, M. Shettar, A. Kakunje, G. Kini
Epigenetics is defined as the changes in gene expression that lead to predictable, stable and possibly heritable alterations in cell function that are not due to changes in DNA sequence. It is of major relevance in psychiatry since environmental factors like stress or substance abuse, significant contribute in causing psychiatric pathologies like depression, anxiety, depression, etc. Epigenetics research in psychiatry would give an opportunity to extend the outlook and approach towards psychiatric pathologies. Hence timely interventions would be sought for. This would also allow gaining access to ‘brain tissue’ from live patients with mental illness and predicting occurrence of or vulnerability to psychiatric illnesses by evaluation of biomarkers, thus preventing, reversing or atleast curbing the progress at an initial stage. There are evidences of work done in the field of epigenetics both in pre-clinical as well as clinical settings. It is remarkable to see how the DNA methylation at various sites can result in alteration of the mental health of an individual and also how this can affect as early as during the first week of life. This is an exciting frontier in psychiatry, providing long sought biomarkers for predicting complex and devastating human behaviours as well as mental illnesses.
{"title":"Epigenetics in Psychiatry","authors":"Nupur Mahatme, M. Shettar, A. Kakunje, G. Kini","doi":"10.32746/ijmhns.2019.v2.i1.13","DOIUrl":"https://doi.org/10.32746/ijmhns.2019.v2.i1.13","url":null,"abstract":"Epigenetics is defined as the changes in gene expression that lead to predictable, stable and possibly heritable alterations in cell function that are not due to changes in DNA sequence. It is of major relevance in psychiatry since environmental factors like stress or substance abuse, significant contribute in causing psychiatric pathologies like depression, anxiety, depression, etc. Epigenetics research in psychiatry would give an opportunity to extend the outlook and approach towards psychiatric pathologies. Hence timely interventions would be sought for. This would also allow gaining access to ‘brain tissue’ from live patients with mental illness and predicting occurrence of or vulnerability to psychiatric illnesses by evaluation of biomarkers, thus preventing, reversing or atleast curbing the progress at an initial stage. There are evidences of work done in the field of epigenetics both in pre-clinical as well as clinical settings. It is remarkable to see how the DNA methylation at various sites can result in alteration of the mental health of an individual and also how this can affect as early as during the first week of life. This is an exciting frontier in psychiatry, providing long sought biomarkers for predicting complex and devastating human behaviours as well as mental illnesses.","PeriodicalId":113988,"journal":{"name":"INDIAN JOURNAL OF MENTAL HEALTH AND NEUROSCIENCES","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123898698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：