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Role of Loupes Magnification in Tracheal Resection and Anastomosis. 放大镜在气管切除和吻合术中的作用
IF 0.6 1区 数学 Q1 MATHEMATICS Pub Date : 2024-02-01 Epub Date: 2023-08-31 DOI: 10.1007/s12070-023-04115-3
Ahmed Yahia Yahia Fouda, Hussein Magdy Abdelkader, Esmail Hassan Ramadan Ahmed, Marwan Ahmed Ibrahim

Tracheal resection and anastomosis is characterized in the last years by significant innovations which are well codified and standardized. Although the mortality rate is markedly reduced, the operation is still not free from risk of complications such as recurrent laryngeal nerve injury, anastomosis dehiscence, granulation tissue formation and restenosis. Pearson FG, Cooper ID, Nelems JL (1975) Primary tracheal anastomosis after resection of the cricoide cartilage with preservation of the recurrent laryngeal nerves. J Thorac Cardiovasc Surg 70:806-16.

Supplementary information: The online version contains supplementary material available at 10.1007/s12070-023-04115-3.

近年来,气管切除和吻合术有了很大的创新,并得到了很好的规范和标准化。虽然死亡率明显降低,但手术仍有可能出现喉返神经损伤、吻合口裂开、肉芽组织形成和再狭窄等并发症。Pearson FG, Cooper ID, Nelems JL (1975) 在切除环状软骨后进行气管吻合术,同时保留喉返神经。J Thorac Cardiovasc Surg 70:806-16.补充信息:在线版本包含补充材料,可在 10.1007/s12070-023-04115-3。
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引用次数: 0
Asymptotic stability of the sine-Gordon kink under odd perturbations 奇摄动下正弦-戈登扭结的渐近稳定性
1区 数学 Q1 MATHEMATICS Pub Date : 2023-10-01 DOI: 10.1215/00127094-2022-0090
Jonas Luhrmann, Wilhelm Schlag
We establish the asymptotic stability of the sine-Gordon kink under odd perturbations that are sufficiently small in a weighted Sobolev norm. Our approach is perturbative and does not rely on the complete integrability of the sine-Gordon model. Key elements of our proof are a specific factorization property of the linearized operator around the sine-Gordon kink, a remarkable nonresonance property exhibited by the quadratic nonlinearity in the Klein–Gordon equation for the perturbation, and a variable coefficient quadratic normal form. We emphasize that the restriction to odd perturbations does not bypass the effects of the odd threshold resonance of the linearized operator. Our techniques have applications to soliton stability questions for several well-known nonintegrable models, for instance, to the asymptotic stability problem for the kink of the ϕ4 model as well as to the conditional asymptotic stability problem for the solitons of the focusing quadratic and cubic Klein–Gordon equations in one space dimension.
我们建立了在加权Sobolev范数中足够小的奇扰动下正弦-戈登扭结的渐近稳定性。我们的方法是微扰的,不依赖于正弦-戈登模型的完全可积性。我们证明的关键要素是正弦-戈登扭结周围线性化算子的一个特殊的因式分解性质,Klein-Gordon方程中摄动的二次非线性所表现出的一个显著的非共振性质,以及一个变系数二次范式。我们强调对奇摄动的限制不能绕过线性化算子的奇阈值共振的影响。我们的技术已应用于几个著名的不可积模型的孤子稳定性问题,例如,对于ϕ4模型的结的渐近稳定性问题,以及在一维空间中聚焦二次和三次Klein-Gordon方程的孤子的条件渐近稳定性问题。
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引用次数: 0
Small amplitude weak almost periodic solutions for the 1d NLS 一维NLS的小振幅弱概周期解
1区 数学 Q1 MATHEMATICS Pub Date : 2023-10-01 DOI: 10.1215/00127094-2022-0089
Luca Biasco, Jessica Elisa Massetti, Michela Procesi
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引用次数: 0
A twisted Yu construction, Harish-Chandra characters, and endoscopy 一个扭曲的Yu结构,Harish-Chandra角色,和内窥镜
1区 数学 Q1 MATHEMATICS Pub Date : 2023-09-01 DOI: 10.1215/00127094-2022-0080
Jessica Fintzen, Tasho Kaletha, Loren Spice
We give a modification of Yu’s construction of supercuspidal representations of a connected reductive group G over a non-Archimedean local field F. This modification restores the validity of certain key intertwining property claims made by Yu, which were recently proved to be false for the original construction. This modification is also an essential ingredient in the construction of supercuspidal L-packets in a preprint by the second author. As further applications, we prove the stability and many instances of endoscopic character identities of these supercuspidal L-packets, subject to some conditions on the base field F. In particular, for regular supercuspidal parameters, we prove all instances of standard endoscopy. In addition, we prove that these supercuspidal L-packets satisfy a recent conjecture by the second author, which, together with standard endoscopy, uniquely characterizes the local Langlands correspondence for supercuspidal L-packets (again subject to the conditions on F). These results are based on a statement of the Harish-Chandra character formula for the supercuspidal representations arising from the twisted Yu construction.
我们给出了Yu在非阿基米德局部域f上的连通约化群G的超尖表示的构造的一个修正。这个修正恢复了Yu所做的一些关键的交织性质声明的有效性,这些声明最近被证明对原始构造是错误的。这种修饰也是第二作者在预印本中构造超尖形l包的重要成分。作为进一步的应用,我们证明了这些超尖形l包的稳定性和内窥镜特征恒等式的许多实例,这些实例在基域f上满足一些条件。特别是对于正则超尖形参数,我们证明了所有标准内窥镜的实例。此外,我们证明了这些超尖l包满足第二作者最近的一个猜想,该猜想与标准内内镜一起,唯一地表征了超尖l包的局部Langlands对应(再次受到F上的条件的限制)。这些结果是基于对由扭曲Yu构造产生的超尖表示的Harish-Chandra特征公式的陈述。
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引用次数: 10
An infinite-rank summand of the homology cobordism group 同调协群的无穷秩和
1区 数学 Q1 MATHEMATICS Pub Date : 2023-09-01 DOI: 10.1215/00127094-2022-0082
Irving Dai, Jennifer Hom, Matthew Stoffregen, Linh Truong
We show that the three-dimensional homology cobordism group admits an infinite-rank summand. It was previously known that the homology cobordism group contains a Z∞-subgroup and a Z-summand. Our proof proceeds by introducing an algebraic variant of the involutive Heegaard Floer package of Hendricks, Manolescu, and Zemke. This is inspired by an analogous argument in the setting of knot concordance due to the second author.
我们证明了三维同调配群允许一个无穷秩和。已知同调协群包含一个Z∞子群和一个Z-和。我们的证明通过引入Hendricks, Manolescu和Zemke的对合Heegaard flower包的代数变体来进行。这是启发了类似的论点,在结和谐的设置,由于第二作者。
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引用次数: 26
Fine-scale distribution of roots of quadratic congruences 二次同余根的精细分布
1区 数学 Q1 MATHEMATICS Pub Date : 2023-09-01 DOI: 10.1215/00127094-2022-0081
Jens Marklof, Matthew Welsh
We establish limit laws for the distribution in small intervals of the roots of the quadratic congruence μ2≡Dmodm, with D>0 square-free and D≢1mod4. This is achieved by translating the problem to convergence of certain geodesic random line processes in the hyperbolic plane. This geometric interpretation allows us in particular to derive an explicit expression for the pair correlation density of the roots.
我们建立了二次同余μ2≡Dmodm的根在小区间内的分布的极限律,其中d>为无平方数,d 1mod4为无平方数。这是通过将问题转化为双曲平面上某些测地线随机线过程的收敛来实现的。这种几何解释特别允许我们推导出根对相关密度的显式表达式。
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引用次数: 2
Bessel models for real unitary groups: The tempered case 实酉群的贝塞尔模型:缓和情况
IF 2.5 1区 数学 Q1 MATHEMATICS Pub Date : 2023-01-01 DOI: 10.1215/00127094-2022-0018
Hang Xue
. We prove the local Gan–Gross–Prasad conjecture for tempered L -packets of real unitary groups. The proof is based on theta lifts and is very simple.
.我们证明了实酉群的调和L-包的局部Gan–Gross–Prasad猜想。这个证明是基于θ提升的,非常简单。
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引用次数: 10
Mean field limit and quantitative estimates with singular attractive kernels 奇异吸引核的平均场极限和定量估计
1区 数学 Q1 MATHEMATICS Pub Date : 2023-01-01 DOI: 10.1215/00127094-2022-0088
Didier Bresch, Pierre-Emmanuel Jabin, Zhenfu Wang
This paper proves the mean field limit and quantitative estimates for many-particle systems with singular attractive interactions between particles. As an important example, a full rigorous derivation (with quantitative estimates) of the Patlak-Keller-Segel model in optimal subcritical regimes is obtained for the first time. To give an answer to this longstanding problem, we take advantage of a new modulated free energy and we prove some precise large deviation estimates encoding the competition between diffusion and attraction. Combined with the range of repulsive kernels, already treated in the s{'e}minaire Laurent Schwartz proceeding [https://slsedp.centre-mersenne.org/journals/SLSEDP/ ], we provide the full proof of results announced by the authors in [C. R. Acad. Sciences Section Maths (2019)].
本文证明了具有奇异吸引相互作用的多粒子系统的平均场极限和定量估计。作为一个重要的例子,首次获得了最优亚临界状态下patak - keller - segel模型的完整严格推导(含定量估计)。为了回答这个长期存在的问题,我们利用一种新的调制自由能,证明了一些精确的大偏差估计,编码了扩散和吸引之间的竞争。结合已经在s{'e}minaire Laurent Schwartz程序[https://slsedp.centre-mersenne.org/journals/SLSEDP/]中处理的排斥核的范围,我们提供了作者在[C]中宣布的结果的完整证明。R. Acad.科学部分数学[2019]。
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引用次数: 31
Pou4f1-Tbr1 transcriptional cascade controls the formation of Jam2-expressing retinal ganglion cells. Pou4f1-Tbr1 转录级联控制着表达 Jam2 的视网膜神经节细胞的形成。
1区 数学 Q1 MATHEMATICS Pub Date : 2023-01-01 Epub Date: 2023-05-18 DOI: 10.3389/fopht.2023.1175568
Takae Kiyama, Halit Y Altay, Tudor C Badea, Chai-An Mao

More than 40 retinal ganglion cell (RGC) subtypes have been categorized in mouse based on their morphologies, functions, and molecular features. Among these diverse subtypes, orientation-selective Jam2-expressing RGCs (J-RGCs) has two unique morphologic characteristics: the ventral-facing dendritic arbor and the OFF-sublaminae stratified terminal dendrites in the inner plexiform layer. Previously, we have discovered that T-box transcription factor T-brain 1 (Tbr1) is expressed in J-RGCs. We further found that Tbr1 is essential for the expression of Jam2, and Tbr1 regulates the formation and the dendritic morphogenesis of J-RGCs. However, Tbr1 begins to express in terminally differentiated RGCs around perinatal stage, suggesting that it is unlikely involved in the initial fate determination for J-RGC and other upstream transcription factors must control Tbr1 expression and J-RGC formation. Using the Cleavage Under Targets and Tagmentation technique, we discovered that Pou4f1 binds to Tbr1 on the evolutionary conserved exon 6 and an intergenic region downstream of the 3'UTR, and on a region flanking the promoter and the first exon of Jam2. We showed that Pou4f1 is required for the expression of Tbr1 and Jam2, indicating Pou4f1 as a direct upstream regulator of Tbr1 and Jam2. Most interestingly, the Pou4f1-bound element in exon 6 of Tbr1 possesses high-level enhancer activity, capable of directing reporter gene expression in J-RGCs. Together, these data revealed a Pou4f1-Tbr1-Jam2 genetic hierarchy as a critical pathway in the formation of J-RGC subtype.

根据小鼠视网膜神经节细胞(RGC)的形态、功能和分子特征,已将其分为 40 多种亚型。在这些不同的亚型中,方向选择性表达Jam2的RGC(J-RGC)有两个独特的形态特征:面向腹侧的树突轴和内丛状层的OFF-sublaminae分层末端树突。此前,我们发现 T-box 转录因子 T-brain 1(Tbr1)在 J-RGCs 中表达。我们进一步发现,Tbr1是Jam2表达的必要条件,Tbr1调控着J-RGCs的形成和树突形态发生。然而,Tbr1大约在围产期开始在终末分化的RGC中表达,这表明它不太可能参与J-RGC的最初命运决定,必须由其他上游转录因子控制Tbr1的表达和J-RGC的形成。利用靶标下裂解和标记技术,我们发现Pou4f1与Tbr1结合在进化保守的第6外显子和3'UTR下游的基因间区域,以及Jam2启动子和第一个外显子的侧翼区域。我们发现 Pou4f1 是 Tbr1 和 Jam2 表达所必需的,这表明 Pou4f1 是 Tbr1 和 Jam2 的直接上游调控因子。最有趣的是,Tbr1 第 6 外显子中与 Pou4f1 结合的元件具有高水平的增强子活性,能够引导 J-RGCs 中报告基因的表达。这些数据共同揭示了Pou4f1-Tbr1-Jam2基因层次结构是形成J-RGC亚型的关键途径。
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引用次数: 0
Arnold diffusion in multidimensional convex billiards 多维凸台球中的阿诺德扩散
IF 2.5 1区 数学 Q1 MATHEMATICS Pub Date : 2023-01-01 DOI: 10.1215/00127094-2022-0073
Andrew Clarke, D. Turaev
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引用次数: 0
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Duke Mathematical Journal
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