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EKOR strata for Shimura varieties with parahoric level structure EKOR地层为志村品种,具有旁倾水平构造
IF 2.5 1区 数学 Q1 MATHEMATICS Pub Date : 2019-10-17 DOI: 10.1215/00127094-2021-0047
Xu Shen, Chia-Fu Yu, Chao Zhang
In this paper we study the geometry of reduction modulo $p$ of the Kisin-Pappas integral models for certain Shimura varieties of abelian type with parahoric level structure. We give some direct and geometric constructions for the EKOR strata on these Shimura varieties, using the theories of $G$-zips and mixed characteristic local $mathcal{G}$-Shtukas. We establish several basic properties of these strata, including the smoothness, dimension formula, and closure relation. Moreover, we apply our results to the study of Newton strata and central leaves on these Shimura varieties.
本文研究了一类具有准水平结构的阿贝尔型Shimura变型的Kisin-Pappas积分模型的约简模p的几何性质。我们利用$G$-zips理论和混合特征局部$mathcal{G}$-Shtukas理论,给出了这些Shimura变异上EKOR地层的一些直接和几何构造。建立了这些地层的几个基本性质,包括光滑度、尺寸公式和闭合关系。此外,我们将我们的结果应用于这些志村品种的牛顿地层和中央叶片的研究。
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引用次数: 22
A generalization of Rasmussen’s invariant, with applications to surfaces in some four-manifolds Rasmussen不变量的推广及其在某些四流形曲面上的应用
IF 2.5 1区 数学 Q1 MATHEMATICS Pub Date : 2019-10-17 DOI: 10.1215/00127094-2022-0039
Ciprian Manolescu, Marco Marengon, Sucharit Sarkar, Michael Willis
We extend the definition of Khovanov-Lee homology to links in connected sums of $S^1 times S^2$'s, and construct a Rasmussen-type invariant for null-homologous links in these manifolds. For certain links in $S^1 times S^2$, we compute the invariant by reinterpreting it in terms of Hochschild homology. As applications, we prove inequalities relating the Rasmussen-type invariant to the genus of surfaces with boundary in the following four-manifolds: $B^2 times S^2$, $S^1 times B^3$, $mathbb{CP}^2$, and various connected sums and boundary sums of these. We deduce that Rasmussen's invariant also gives genus bounds for surfaces inside homotopy 4-balls obtained from $B^4$ by Gluck twists. Therefore, it cannot be used to prove that such homotopy 4-balls are non-standard.
我们将Khovanov-Lee同调的定义推广到连通和为$S^1乘S^2$的连接,并构造了这些流形中零同调连接的Rasmussen型不变量。对于$S^1乘以S^2$中的某些链接,我们通过根据Hochschild同调重新解释它来计算不变量。作为应用,我们证明了以下四个流形中Rasmussen型不变量与具有边界的曲面亏格有关的不等式:$B^2×S^2,$S^1×B^3,$mathbb{CP}^2,以及它们的各种连通和和边界和。我们推导出Rasmussen不变量也给出了由Gluck扭曲从$B^4$得到的同胚4-球内曲面的亏格界。因此,它不能用来证明这样的同伦球是非标准的。
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引用次数: 21
Stromal vascular fraction promotes migration of fibroblasts and angiogenesis through regulation of extracellular matrix in the skin wound healing process. 基质血管成分在皮肤伤口愈合过程中通过调节细胞外基质促进成纤维细胞迁移和血管生成。
IF 2.1 1区 数学 Q1 MATHEMATICS Pub Date : 2019-10-17 DOI: 10.1186/s13287-019-1415-6
Hongsen Bi, Hui Li, Chen Zhang, Yiqing Mao, Fangfei Nie, Ying Xing, Wuga Sha, Xi Wang, David M Irwin, Huanran Tan

Background: A refractory wound is a typical complication of diabetes and is a common outcome after surgery. Current approaches have difficulty in improving wound healing. Recently, non-expanded stromal vascular fraction (SVF), which is derived from mature fat, has opened up new directions for the treatment of refractory wound healing. The aim of the current study is to systematically investigate the impact of SVF on wound healing, including the rate and characteristics of wound healing, ability of fibroblasts to migrate, and blood transport reconstruction, with a special emphasis on their precise molecular mechanisms.

Methods: SVF was isolated by digestion, followed by filtration and centrifugation, and then validated by immunocytochemistry, a MTS proliferation assay and multilineage potential analysis. A wound model was generated by creating 6-mm-diameter wounds, which include a full skin defect, on the backs of streptozocin-induced hyperglycemic mice. SVF or human adipose-derived stem cell (hADSC) suspensions were subcutaneously injected, and the wounds were characterized over a 9-day period by photography and measurements. A scratch test was used to determine whether changes in the migratory ability of fibroblasts occurred after co-culture with hADSCs. Angiogenesis was observed with human umbilical vein endothelial cells. mRNA from fibroblasts, endotheliocyte, and skin tissue were sequenced by high-throughput RNAseq, and differentially expressed genes, and pathways, potentially regulated by SVF or hADSCs were bioinformatically analyzed.

Results: Our data show that hADSCs have multiple characteristics of MSC. SVF and hADSCs significantly improved wound healing in hyperglycemic mice. hADSCs improve the migratory ability of fibroblasts and capillary structure formation in HUVECs. SVF promotes wound healing by focusing on angiogenesis and matrix remodeling.

Conclusions: Both SVF and hADSCs improve the function of fibroblast and endothelial cells, regulate gene expression, and promote skin healing. Various mechanisms likely are involved, including migration of fibroblasts, tubulogenesis of endothelial cells through regulation of cell adhesion, and cytokine pathways.

背景:难愈性伤口是糖尿病的典型并发症,也是手术后的常见结果。目前的方法难以改善伤口愈合。最近,从成熟脂肪中提取的非扩张基质血管成分(SVF)为治疗难治性伤口愈合开辟了新方向。本研究的目的是系统研究 SVF 对伤口愈合的影响,包括伤口愈合的速度和特点、成纤维细胞迁移能力和血运重建,并特别强调其精确的分子机制:方法:通过消化、过滤和离心分离 SVF,然后通过免疫细胞化学、MTS 增殖试验和多线性潜能分析进行验证。通过在链脲佐钦诱导的高血糖小鼠背上创建直径为 6 毫米的伤口(包括全皮肤缺损)来制作伤口模型。皮下注射SVF或人类脂肪来源干细胞(hADSC)悬浮液,并通过拍照和测量对伤口进行为期9天的鉴定。用划痕试验确定成纤维细胞与 hADSCs 共同培养后的迁移能力是否发生变化。通过高通量 RNAseq 对成纤维细胞、内皮细胞和皮肤组织的 mRNA 进行测序,并对 SVF 或 hADSCs 可能调控的差异表达基因和通路进行生物信息学分析:结果:我们的数据显示,hADSCs具有间充质干细胞的多种特征。SVF和hADSCs能明显改善高血糖小鼠的伤口愈合;hADSCs能改善成纤维细胞的迁移能力和HUVECs毛细血管结构的形成。SVF通过关注血管生成和基质重塑促进伤口愈合:结论:SVF 和 hADSCs 都能改善成纤维细胞和内皮细胞的功能,调节基因表达,促进皮肤愈合。结论:SVF 和 hADSCs 都能改善成纤维细胞和内皮细胞的功能,调节基因表达,促进皮肤愈合。其中可能涉及多种机制,包括成纤维细胞的迁移、通过调节细胞粘附促进内皮细胞的小管生成以及细胞因子途径。
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引用次数: 0
Apolarity, border rank, and multigraded Hilbert scheme Apollarity、边秩和多重等级Hilbert方案
IF 2.5 1区 数学 Q1 MATHEMATICS Pub Date : 2019-10-04 DOI: 10.1215/00127094-2021-0048
Weronika Buczy'nska, Jaroslaw Buczy'nski
We introduce an elementary method to study the border rank of polynomials and tensors, analogous to the apolarity lemma. This can be used to describe the border rank of all cases uniformly, including those very special ones that resisted a systematic approach. We also define a border rank version of the variety of sums of powers and analyse how it is useful in studying tensors and polynomials with large symmetries. In particular, it can also be applied to provide lower bounds for the border rank of some very interesting tensors, such as the matrix multiplication tensor. We work in a general setting, where the base variety is not necessarily a Segre or Veronese variety, but an arbitrary smooth toric projective variety. A critical ingredient of our work is an irreducible component of a multigraded Hilbert scheme related to the toric variety in question.
我们介绍了一种研究多项式和张量的边秩的初等方法,类似于概化引理。这可以用来统一描述所有案件的边界等级,包括那些抵制系统方法的非常特殊的案件。我们还定义了各种幂和的边秩版本,并分析了它在研究具有大对称性的张量和多项式时是如何有用的。特别地,它还可以用于为一些非常有趣的张量的边界秩提供下界,例如矩阵乘法张量。我们在一个一般的环境中工作,其中基变体不一定是Segre或Veronese变体,而是任意光滑复曲面投影变体。我们工作的一个关键组成部分是与所讨论的复曲面变体相关的多阶希尔伯特方案的不可约分量。
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引用次数: 27
On the minimal diameter of closed hyperbolic surfaces 关于闭双曲面的极小直径
IF 2.5 1区 数学 Q1 MATHEMATICS Pub Date : 2019-09-26 DOI: 10.1215/00127094-2020-0083
Thomas Budzinski, N. Curien, Bram Petri
We prove that the minimal diameter of a hyperbolic compact orientable surface of genus $g$ is asymptotic to $log g$ as $g to infty$. The proof relies on a random construction, which we analyse using lattice point counting theory and the exploration of random trivalent graphs.
我们证明了亏格$g$的双曲紧致可定向曲面的最小直径渐近于$logg$为$gtoinfty$。证明依赖于一个随机结构,我们使用格点计数理论和随机三价图的探索来分析它。
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引用次数: 11
The fourth moment of Dirichlet L-functions along a coset and the Weyl bound 沿coset和Weyl界的Dirichlet l函数的第四矩
IF 2.5 1区 数学 Q1 MATHEMATICS Pub Date : 2019-08-27 DOI: 10.1215/00127094-2022-0069
Ian Petrow, M. Young
We prove a Lindelof-on-average upper bound for the fourth moment of Dirichlet $L$-functions of conductor $q$ along a coset of the subgroup of characters modulo $d$ when $q^*|d$, where $q^*$ is the least positive integer such that $q^2|(q^*)^3$. As a consequence, we finish the previous work of the authors and establish a Weyl-strength subconvex bound for all Dirichlet $L$-functions with no restrictions on the conductor.
证明了导体q$的Dirichlet $L$-函数沿模$d$的子群的余集的四阶矩的Lindelof-on-average上界,当$q^*|d$时,其中$q^*$是最小的正整数,使得$q^2|(q^*)^3$。因此,我们完成了作者之前的工作,并建立了对导体没有限制的所有Dirichlet $L$-函数的weyl强度次凸界。
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引用次数: 35
On the remainder term of the Weyl law for congruence subgroups of Chevalley groups Chevalley群的同余子群的Weyl律的余项
IF 2.5 1区 数学 Q1 MATHEMATICS Pub Date : 2019-08-19 DOI: 10.1215/00127094-2020-0094
Tobias Finis, E. Lapid
Let $X$ be a locally symmetric space defined by a simple Chevalley group $G$ and a congruence subgroup of $G(mathbb Q)$. In this generality, the Weyl law for $X$ was proved by Lindenstrauss--Venkatesh. In the case where $G$ is simply connected, we sharpen their result by giving a power saving estimate for the remainder term.
设$X$是一个局部对称空间,由一个简单的Chevalley群$G$和$G(mathbb Q)$的同余子群$G$定义。在这种通用性下,Lindenstrauss—Venkatesh证明了$X$的Weyl定律。在$G$单连通的情况下,我们通过给出剩余项的省电估计来锐化它们的结果。
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引用次数: 6
Symmetry in stationary and uniformly rotating solutions of active scalar equations 有源标量方程稳态和均匀旋转解的对称性
IF 2.5 1区 数学 Q1 MATHEMATICS Pub Date : 2019-08-05 DOI: 10.1215/00127094-2021-0002
Javier G'omez-Serrano, Jaemin Park, Jia Shi, Yao Yao
In this paper, we study the radial symmetry properties of stationary and uniformly-rotating solutions of the 2D Euler and gSQG equations, both in the smooth setting and the patch setting. For the 2D Euler equation, we show that any smooth stationary solution with compactly supported and nonnegative vorticity must be radial, without any assumptions on the connectedness of the support or the level sets. In the patch setting, for the 2D Euler equation we show that every uniformly-rotating patch $D$ with angular velocity $Omega leq 0$ or $Omegageq frac{1}{2}$ must be radial, where both bounds are sharp. For the gSQG equation we obtain a similar symmetry result for $Omegaleq 0$ or $Omegageq Omega_alpha$ (with the bounds being sharp), under the additional assumption that the patch is simply-connected. These results settle several open questions in [T. Hmidi, J. Evol. Equ., 15(4): 801-816, 2015] and [F. de la Hoz, Z. Hassainia, T. Hmidi, and J. Mateu, Anal. PDE, 9(7):1609-1670, 2016] on uniformly-rotating patches. Along the way, we close a question on overdetermined problems for the fractional Laplacian [R. Choksi, R. Neumayer, and I. Topaloglu, Arxiv preprint arXiv:1810.08304, 2018, Remark 1.4], which may be of independent interest. The main new ideas come from a calculus of variations point of view.
本文研究了二维Euler方程和gSQG方程在光滑和贴片条件下的稳态解和均匀旋转解的径向对称性。对于二维欧拉方程,我们证明了任何具有紧支撑和非负涡度的光滑平稳解必须是径向的,而不需要假设支撑或水平集的连通性。在贴片设置中,对于二维欧拉方程,我们表明每个具有角速度$Omega leq 0$或$Omegageq frac{1}{2}$的均匀旋转贴片$D$必须是径向的,其中两个边界都是尖锐的。对于gSQG方程,我们在附加假设patch是单连通的情况下,对$Omegaleq 0$或$Omegageq Omega_alpha$(边界很明显)获得了类似的对称结果。这些结果解决了[T]中的几个开放性问题。J.进化。等式。[j] .中国机械工程,2015(4):801-816。de la Hoz, Z. Hassainia, T. Hmidi和J. Mateu, Anal。地球物理学报,9(7):1609-1670,2016 [j]。在此过程中,我们结束了分数阶拉普拉斯函数的超定问题。Choksi, R. Neumayer, and I. Topaloglu, Arxiv预印本[j] . [j] .预印本[j] . vol . 11(4):1 - 2, 2018。主要的新思想来自变分演算的观点。
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引用次数: 43
Symplectic homology of convex domains and Clarke’s duality 凸域的辛同调与Clarke对偶
IF 2.5 1区 数学 Q1 MATHEMATICS Pub Date : 2019-07-17 DOI: 10.1215/00127094-2021-0025
Alberto Abbondandolo, Jungsoo Kang
We prove that the Floer complex that is associated with a convex Hamiltonian function on $mathbb{R}^{2n}$ is isomorphic to the Morse complex of Clarke's dual action functional that is associated with the Fenchel-dual Hamiltonian. This isomorphism preserves the action filtrations. As a corollary, we obtain that the symplectic capacity from the symplectic homology of a convex domain with smooth boundary coincides with the minimal action of closed characteristics on its boundary.
我们证明了与$mathbb{R}^{2n}$上的凸Hamilton函数相关的Floer复形同构于与Fenchel对偶Hamilton相关的Clarke对偶作用泛函的Morse复形。这种同构保留了动作过滤。作为推论,我们从具有光滑边界的凸域的辛同调中得到了辛容量与闭特征对其边界的最小作用一致。
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引用次数: 12
Trees, length spectra for rational maps via barycentric extensions, and Berkovich spaces 树、通过重心扩展的有理映射的长度谱和Berkovich空间
IF 2.5 1区 数学 Q1 MATHEMATICS Pub Date : 2019-07-14 DOI: 10.1215/00127094-2022-0056
Yusheng Luo
In this paper, we study the dynamics of degenerating sequences of rational maps on Riemann sphere $hat{mathbb{C}}$ using $mathbb{R}$-trees. Given a sequence of degenerating rational maps, we give two constructions for limiting dynamics on $mathbb{R}$-trees: one geometric and one algebraic. The geometric construction uses the ultralimit of rescalings of barycentric extensions of rational maps, while the algebraic construction uses the Berkovich space of complexified Robinson's field. We show the two approaches are equivalent. The limiting dynamics on the $mathbb{R}$-tree are analogues to isometric group actions on $mathbb{R}$-trees studied in Kleinian groups and Teichmuller theory. We use the limiting map to classify hyperbolic components of rational maps that admit degeneracies with bounded length spectra (multipliers).
在本文中,我们使用$mathbb{R}$树研究了黎曼球面$hat{mathbb}C}}$上有理映射的退化序列的动力学。给定一系列退化有理映射,我们给出了$mathbb{R}$-树上极限动力学的两个构造:一个是几何的,一个是代数的。几何构造使用有理映射的重心扩展的重缩放的超极限,而代数构造使用复杂Robinson域的Berkovich空间。我们证明了这两种方法是等效的。$mathbb{R}$-树上的极限动力学类似于Kleinian群和Teichmuller理论中研究的$mathbb{R}$树上的等距群作用。我们使用极限映射对有理映射的双曲分量进行分类,这些有理映射允许具有有界长度谱的退化(乘数)。
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引用次数: 9
期刊
Duke Mathematical Journal
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