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Digital rectal stimulation associated with psychiatric disorders as a rare reason of solitary rectal ulcer in children and adolescents: a case series study 指直肠刺激与精神障碍相关,是儿童和青少年孤立性直肠溃疡的罕见原因:一项病例系列研究
Pub Date : 2019-01-01 DOI: 10.14744/dajpns.2019.00050
F. Çetin, H. Emiroğlu, Saliha Calisir, S. Türkoğlu
How to cite this article: Cetin FH, Emiroglu HH, Calisir S, Turkoglu S. Digital rectal stimulation associated with psychiatric disorders as a rare reason of solitary rectal ulcer in children and adolescents: a case series. Dusunen Adam The Journal of Psychiatry and Neurological Sciences 2019;32:352-354. Digital rectal stimulation associated with psychiatric disorders as a rare reason of solitary rectal ulcer in children and adolescents: a case series
Cetin FH, Emiroglu HH, Calisir S, Turkoglu S。指直肠刺激与精神障碍相关,是儿童和青少年孤立性直肠溃疡的罕见原因:一个病例系列。Dusunen Adam精神病学和神经科学杂志2019;32:352-354。指直肠刺激与精神障碍相关是儿童和青少年孤立性直肠溃疡的罕见原因:一个病例系列
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引用次数: 0
The association between hope, anxiety, depression, coping strategies and perceived social support in patients with chronic kidney disease 慢性肾病患者的希望、焦虑、抑郁、应对策略与感知社会支持的关系
Pub Date : 2019-01-01 DOI: 10.14744/dajpns.2019.00006
B. Yucens
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引用次数: 2
Investigation of second to fourth finger length ratio (2D:4D) in schizophrenia patients 精神分裂症患者第二指与第四指长度比(2D:4D)的研究
Pub Date : 2019-01-01 DOI: 10.14744/dajpns.2019.00043
Faruk Kılıç
Correspondence: Faruk Kilic, Suleyman Demirel University, Faculty of Medicine, Department of Psychiatry, Isparta Turkey Phone: +90 246 211 93 35 E-mail: drfarukk33@hotmail.com Received: August 15, 2019; Revised: September 23, 2019; Accepted: October 18, 2019 ABSTRACT Objective: Schizophrenia is a significant burden for the patient and causes great costs for society. The etiology of schizophrenia, which is known to be a neurodevelopmental disorder, has not been fully elucidated. Differences in prenatal gonadal hormones have been suggested to play a role in the pathogenesis of schizophrenia. An easy way to evaluate a biomarker that gives insight about prenatal androgen is the second to fourth digit ratio (2D:4D) of the hand. In this study, we aimed to compare the 2D:4D ratio of schizophrenia patients to healthy controls and to investigate the relationship with positive and negative symptoms. Method: Seventy-six patients with schizophrenia and 67 healthy controls were included in the study. Finger lengths were measured from the proximal finger crease to the tip using a digital vernier caliper with a precision of 0.01 mm. The Scale for the Assessment of Positive Symptoms (SAPS) and the Scale for the Assessment of Negative Symptoms (SANS) were used to evaluate the symptoms of schizophrenia. Results: While the left 2D:4D ratio of the patients with schizophrenia was not different from the controls’, the right 2D:4D ratio was significantly lower. The correlation between finger lengths and the SAPS and SANS scores by gender showed a negative correlation of the left and right 2D:4D ratio with the SANS scores in female patients, while the SANS scores were found to be positively correlated with the right 2D:4D ratio in men. Conclusion: The findings of our study support the view that the right 2D:4D ratio may be an indicator for schizophrenia.
通讯:Faruk Kilic, Suleyman Demirel University,医学院,精神科,Isparta土耳其电话:+90 246 211 93 35 E-mail: drfarukk33@hotmail.com收件时间:2019年8月15日;修订日期:2019年9月23日;摘要目的:精神分裂症是患者的重大负担,也是社会的巨大成本。精神分裂症是一种神经发育障碍,其病因尚未完全阐明。产前性腺激素的差异被认为在精神分裂症的发病机制中起作用。一个简单的方法来评估生物标志物,提供产前雄激素的洞察是手的第二和第四指的比例(2D:4D)。在本研究中,我们旨在比较精神分裂症患者与健康对照组的2D:4D比值,并探讨其与阳性和阴性症状的关系。方法:选取76例精神分裂症患者和67例健康对照。使用精度为0.01 mm的数字游标卡尺测量从手指近端折痕到指尖的手指长度。采用阳性症状评定量表(SAPS)和阴性症状评定量表(SANS)对精神分裂症的症状进行评定。结果:精神分裂症患者左侧二维:四维比值与对照组无显著差异,右侧二维:四维比值显著低于对照组。手指长度与SAPS和SANS评分的性别相关性显示,女性患者的左右2D:4D比与SANS评分呈负相关,而男性患者的右手2D:4D比与SANS评分呈正相关。结论:我们的研究结果支持正确的2D:4D比值可能是精神分裂症的一个指标。
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引用次数: 3
Suicide by jumping from a height in a university hospital: two cases 在大学医院跳楼自杀:两例
Pub Date : 2019-01-01 DOI: 10.14744/DAJPNS.2019.00010
A. E. Altınöz, Duriye Gizem Tosun Dilci, Ferdi Köşger, Altan Eşsizoğlu
Suicide among inpatients can be devastating for other patients and hospital staff. Studies show that cases of inpatient suicides in general hospitals receive less attention than inpatient suicides in psychiatric hospitals. Studies on cases of inpatient suicide in general hospitals are usually in the form of case reports or case series, and potential suicide risk factors are unknown. Many significant differences are reported between inpatient suicides in general hospitals and inpatient suicides in psychiatry clinics. Here we report two cases of completed suicide after jumping from a height while receiving inpatient treatment at a University Hospital. As serious physical illnesses are frequently accompanied by psychiatric disorders that increase suicide risk, measures should be taken to prevent inpatient suicides in hospitals admitting patients with physical illnesses. Hospitals should keep regular records about inpatients who attempt or commit suicide during their treatment in the hospital or during treatment breaks, because this would provide valuable data to examine and prevent cases of inpatient suicide.
住院病人的自杀对其他病人和医院工作人员来说可能是毁灭性的。研究表明,综合医院的住院患者自杀案件比精神病院的住院患者自杀案件受到的关注要少。对综合医院住院患者自杀案例的研究多以病例报告或病例系列的形式进行,潜在的自杀危险因素未知。综合医院的住院病人自杀与精神科诊所的住院病人自杀有许多显著差异。在这里,我们报告两例完成自杀后,从高处跳下来,而在接受住院治疗的大学医院。由于严重的身体疾病经常伴有增加自杀风险的精神疾病,应采取措施防止住院病人在接收身体疾病患者的医院自杀。医院应定期记录住院病人在住院治疗期间或治疗休息期间企图或自杀的情况,因为这将为检查和预防住院病人自杀案件提供宝贵的数据。
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引用次数: 0
Post stroke depression and related factors 脑卒中后抑郁及相关因素
Pub Date : 2019-01-01 DOI: 10.14744/dajpns.2019.00007
M. Yıldırım
Objective: Depressive symptoms are frequently observed in patients with stroke. In this study, we investigated the prevalence of depression and the factors affecting depression in patients with chronic stroke. Method: The study included 90 patients having had sustained a stroke attack at least 6 months previously. The demographic characteristics, time since stroke, hemiplegic side, etiology of stroke, stroke-related risk factors, complications and accompanying neurological disorders, drug use, and the presence of additional diseases were questioned. Depressive symptoms were assessed by using the Beck Depression Scale (BDS). The patients were divided into two groups according to the BDS score: group 1 included those with depression (BDS score ≥17), and group 2 included those without depression (BDS score
目的:脑卒中患者常出现抑郁症状。在本研究中,我们调查了慢性脑卒中患者抑郁的患病率及影响抑郁的因素。方法:本研究纳入90例至少6个月前中风发作的患者。对人口统计学特征、中风时间、偏瘫侧、中风病因、中风相关危险因素、并发症和伴随的神经系统疾病、药物使用和其他疾病的存在进行了质疑。采用贝克抑郁量表(BDS)评估抑郁症状。根据BDS评分将患者分为两组:1组为抑郁患者(BDS评分≥17),2组为无抑郁患者(BDS评分)
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引用次数: 4
Intrinsic oscillations of auditory networks in schizophrenia and bipolar disorder 精神分裂症和双相情感障碍中听觉网络的内在振荡
Pub Date : 2019-01-01 DOI: 10.14744/dajpns.2019.00002
M. Atagun
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引用次数: 1
The Turkish validity and reliability study of the body esteem scale 身体自尊量表的土耳其语效度与信度研究
Pub Date : 2019-01-01 DOI: 10.14744/dajpns.2019.00049
emine sevinç
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引用次数: 0
Evaluation of the diagnostic continuity of unspecified mood disorder 未明确情绪障碍诊断连续性的评价
Pub Date : 2019-01-01 DOI: 10.14744/DAJPNS.2019.00015
H. Taş, Ozlem Ozusta
Correspondence: Halil İbrahim Tas, Canakkale Onsekiz Mart University, Faculty of Medicine, Department of Psychiatry, Canakkale Turkey Phone: +90 286 218 00 18 20 60 E-mail: tashalilibrahim@gmail.com Received: October 23, 2018; Revised: December 19, 2018; Accepted: March 13, 2019 ABSTRACT Objective: According to ICD-10, the diagnosis of unspecified mood disorder (UMD), coded ‘F39,’ is used when there is insufficient or contradictory information about the patient and the symptoms of mood disorder are not sufficient to diagnose a specific mood disorder. Information about the frequency, diagnostic validity and continuity of this diagnosis is unsatisfactory. Therefore, we aimed to evaluate the prevalence and diagnostic continuity of this diagnosis among individuals diagnosed with UMD in our outpatient clinic. Method: Included in the study were patients who presented to the psychiatry outpatient unit for the first time between January 2011 and December 2017, were diagnosed with mood disorder code ‘F39’ at the first admission, and presented at least three times in different periods (n=48). Outpatient unit records were evaluated retrospectively and the data were analyzed with SPSS version 19.0. Results: The mean follow-up period of 48 patients included in the study was 14.4±13.9 months. The final diagnoses of the patients after follow-up were UMD (42%), depressive disorder (25%), bipolar disorder (17%), and anxiety disorder (10%). It was found that the duration of the follow-up for individuals diagnosed with UMD was significantly shorter than for those with a different diagnosis. No significant difference was found between final diagnoses in terms of age, gender, level of education, and marital status. Conclusion: UMD has less diagnostic stability than other mood disorders. Therefore, longer follow-up durations are needed in patients with UMD, and it is crucial to reconsider the diagnosis during follow-up. Further studies with larger samples are needed to elucidate the stability of UMD.
通讯:Halil İbrahim Tas,恰纳卡莱Onsekiz Mart大学,医学院,精神科,恰纳卡莱土耳其电话:+90 286 218 00 18 20 60 E-mail: tashalilibrahim@gmail.com收到:2018年10月23日;修订日期:2018年12月19日;摘要目的:根据ICD-10,当关于患者的信息不充分或相互矛盾,并且情绪障碍的症状不足以诊断特定情绪障碍时,使用编码为“F39”的未指定情绪障碍(UMD)的诊断。关于这种诊断的频率、诊断有效性和连续性的信息不令人满意。因此,我们的目的是评估在门诊诊断为UMD的个体中这种诊断的患病率和诊断连续性。方法:纳入2011年1月至2017年12月首次到精神科门诊就诊的患者,首次入院时诊断为情绪障碍代码“F39”,并在不同时期至少出现3次(n=48)。回顾性评估门诊单位记录,并使用SPSS 19.0版本对数据进行分析。结果:纳入研究的48例患者平均随访时间为14.4±13.9个月。随访后患者的最终诊断为UMD(42%),抑郁症(25%),双相情感障碍(17%)和焦虑症(10%)。研究发现,诊断为UMD的个体的随访时间明显短于其他诊断的个体。最终诊断在年龄、性别、教育程度和婚姻状况方面无显著差异。结论:与其他心境障碍相比,UMD的诊断稳定性较差。因此,UMD患者需要更长的随访时间,在随访中重新考虑诊断是至关重要的。进一步的研究需要更大的样本来阐明UMD的稳定性。
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引用次数: 1
The good face of Cannabis sativa: Cannabidiol 大麻的好面孔:大麻二酚
Pub Date : 2019-01-01 DOI: 10.14744/dajpns.2019.00041
C. Evren
Cannabidiol (CBD) is a phytocannabinoid derived from the Cannabis sativa plant, just l ike tetrahydrocannabinol (THC), but in contrast with the latter it shows no psychoactive effect. Unlike THC, CBD does not activate the reward system; however, it effects the opioid, serotonin, and cannabinoid receptor systems. Therefore, it is thought to be promising for the treatment of drug addiction. In particular, it acts as a non-competitive antagonist of CB1 receptor within the cannabinoid system (1). However, CBD has been shown not to be acting directly on the CB1 receptor. Most studies reported that it has no effect on the CB1 receptor at all, while some studies showed weak agonistic or weak antagonistic effects. CBD also has a low affinity for another cannabinoid receptor, the CB2 receptor (2). CBD can be converted into THC in some animal species and in laboratory settings, but this conversion does not happen in the human body (2,3). Because of its action on various receptors, cannabidiol’s effect is being investigated in many physical or psychiatric diseases. Clinical studies for the treatment of epilepsy are ongoing and positive results have been reported. In some preclinical studies, although not mainly in epilepsy, CBD has been shown to have neuroprotective, anxiolytic, antipsychotic, analgesic, anti-inflammatory, anti-asthmatic, and antitumor features (2). The therapeutic use of CBD has also been investigated in substance use disorders. Several preclinical studies have reported that CBD may have a therapeutic effect on opioid, cocaine, and psychostimulant addiction. Some studies have also obtained data suggesting that CBD may be beneficial in cannabis and tobacco addiction in humans (4). Substance use causes dysregulation in the mesolimbic circuit. CBD alleviates this dysregulation when administered regularly. Because of this feature, CBD was considered to be beneficial in substance use disorder. It is considered that its efficacy may depend on the dose and on whether it is administered before or in combination with the substance used (1). CBD is also thought to blunt the reward-facilitating effect of substance use through 5HT1A receptor agonism, which is effective in reducing stress and anxiety in the mesolimbic system. This suggestion is based on selective serotonin reuptake inhibitors and other antidepressants reducing substance use by alleviating mood symptoms. ABSTRACT
大麻二酚(CBD)是一种从大麻植物中提取的植物大麻素,与四氢大麻酚(THC)一样,但与后者相比,它没有精神活性作用。与四氢大麻酚不同,CBD不会激活奖励系统;然而,它会影响阿片类药物、血清素和大麻素受体系统。因此,它被认为是有希望的治疗药物成瘾。特别是,它在大麻素系统中作为CB1受体的非竞争性拮抗剂(1)。然而,CBD已被证明不直接作用于CB1受体。大多数研究报道它对CB1受体没有作用,而一些研究显示弱激动或弱拮抗作用。CBD对另一种大麻素受体CB2受体的亲和力也很低(2)。CBD可以在一些动物物种和实验室环境中转化为四氢大麻酚,但这种转化不会发生在人体中(2,3)。由于其对多种受体的作用,大麻二酚在许多身体或精神疾病中的作用正在被研究。治疗癫痫的临床研究正在进行中,已报告了积极的结果。在一些临床前研究中,CBD已被证明具有神经保护、抗焦虑、抗精神病、镇痛、抗炎、抗哮喘和抗肿瘤的特征(2)。CBD的治疗用途也被研究用于物质使用障碍。一些临床前研究报告称,CBD可能对阿片类药物、可卡因和精神兴奋剂成瘾有治疗作用。一些研究也获得了数据,表明CBD可能对人类的大麻和烟草成瘾有益(4)。物质使用会导致中脑边缘回路失调。定期服用CBD可以缓解这种失调。由于这一特点,CBD被认为对药物使用障碍有益。据认为,其功效可能取决于剂量,以及是否在使用物质之前或与使用物质联合使用(1)。CBD还被认为通过5HT1A受体激动作用减弱物质使用的奖励促进作用,有效减少中脑边缘系统的压力和焦虑。这一建议是基于选择性血清素再摄取抑制剂和其他抗抑郁药通过减轻情绪症状来减少物质使用。摘要
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引用次数: 2
The Difficulties in Emotion Regulation, Separation Anxiety and Impulsivity as Predictors of Women’s Intimate Partner Violence Experiences 情绪调节困难、分离焦虑和冲动性是女性亲密伴侣暴力经历的预测因子
Pub Date : 2019-01-01 DOI: 10.14744/DAJPNS.2019.00016
Yasemin Kayha, Nermin Taskale
Correspondence: Yasemin Kahya, Social Sciences University of Ankara, Faculty of Humanities and Social Sciences, Department of Psychology, Hukumet Meydani, No. 2, 06030 Ulus, Altindag, Ankara Turkey Phone: +90 312 596 44 44 E-mail: yaseminoruclular@gmail.com Received: November 21, 2018; Revised: December 11, 2018; Accepted: March 11, 2019 ABSTRACT Objective: The first purpose of the current study was to examine the typology of intimate partner violence experiences of community sample women via two-step cluster analysis. The second purpose was to investigate how difficulties in emotion regulation, separation anxiety, and impulsivity would predict the clusters of intimate partner violence including both victim and perpetrator roles. Method: A total of 253 female participants who were married/in a relationship currently or during the past year were included in the statistical analyses. Participants completed online a Demographic Information Form, the Revised Conflict Tactics Scale-2, the Difficulties in Emotion Regulation Scale, the Adult Separation Anxiety Questionnaire, and the Short Form of the Barratt Impulsiveness Scale. Results: The two-step clustering method indicated that violence experiences of women in the community who were mostly victims of psychological violence fell into two different clusters of low and moderate violence experiences. The total scores of difficulties in emotion regulation and separation anxiety symptoms increased the likelihood of being in the moderate violence cluster while the total score of impulsivity was not related to violence clusters. Conclusion: Violence experience of women in the community is a complex phenomenon that simultaneously includes victim and perpetrator roles and is experienced at different levels. Findings underlined the role of women’s affect-regulation difficulties and their feelings towards significant others and intimate relationships in their violence experiences.
通信:Yasemin Kahya,安卡拉社会科学大学,人文社会科学学院,心理学系,Hukumet Meydani, 2号,06030 Ulus, Altindag,土耳其安卡拉电话:+90 312 596 44 44 E-mail: yaseminoruclular@gmail.com收件时间:2018年11月21日;修订日期:2018年12月11日;摘要目的:本研究的第一个目的是通过两步聚类分析来研究社区样本女性亲密伴侣暴力经历的类型。第二个目的是研究情绪调节困难、分离焦虑和冲动性如何预测包括受害者和加害者角色在内的亲密伴侣暴力集群。方法:对253名已婚或有恋爱关系的女性进行统计分析。被试在线完成人口统计信息表、冲突策略修正量表-2、情绪调节困难量表、成人分离焦虑问卷和Barratt冲动量表简表。结果:两步聚类方法表明,社区中以心理暴力受害者为主的妇女的暴力经历分为轻度和中度暴力经历两个不同的聚类。情绪调节困难总分和分离焦虑总分增加了轻度暴力类的可能性,冲动总分与暴力类无相关性。结论:社区妇女的暴力经历是一个复杂的现象,同时包括受害者和加害者的角色,并在不同层次上经历。调查结果强调了妇女的情感调节困难及其对重要他人和亲密关系的感情在其暴力经历中的作用。
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引用次数: 3
期刊
Dusunen Adam: The Journal of Psychiatry and Neurological Sciences
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