[This retracts the article DOI: 10.1155/2022/4746121.].
[This retracts the article DOI: 10.1155/2022/4746121.].
Objective: To summarize the best evidence of emergency target blood pressure management for acute aortic dissection and provide guidance for evidence-based practice of emergency target blood pressure management.
Methods: According to the "6S" evidence pyramid model, the evidence of emergency target blood pressure management of acute aortic dissection in various foreign databases and websites of professional associations from January 1, 2010, to August 1, 2022, was retrieved, including clinical decision-making, guidelines, expert consensus, systematic reviews, randomized controlled trials, cohort studies, and case series. Two researchers used the corresponding document quality evaluation tools to evaluate the documents and extracted and summarized the evidence of documents above grade B.
Results: A total of 17 articles were included, including 6 clinical decision-making articles, 5 guidelines, 2 expert consensus articles, 1 systematic review article, 1 randomized controlled trial article, 1 cohort study article, and 1 case series article, forming 36 best evidences, including 9 topics, which are target value setting, management strategy, disease observation, medical history collection, monitoring methods, vasoactive drugs, nonvasoactive drugs, related examinations, and patient education.
Conclusion: The best evidence summarized provides a reference for doctors and nurses in the emergency department to manage the emergency target blood pressure of patients with acute aortic dissection. It is recommended that doctors and nurses in the emergency department follow the best evidence summarized to develop individualized target blood pressure management plan for patients.
Objectives: To analyze the effects of deep hyperthermia combined with intraperitoneal chemotherapy on liver-kidney function, immune function, and long-term survival in patients with abdominal metastases.
Methods: A total of 88 patients with abdominal metastases confirmed in the hospital were enrolled as the research objects between August 2018 and August 2021. They were randomly divided into control group (n = 44) and observation group (n = 44). The control group was treated with intraperitoneal chemotherapy, while observation group was additionally treated with deep hyperthermia. The general clinical data of patients were recorded. The short-term and long-term curative effects were evaluated. The occurrence of side effects in both groups was recorded. Before and after treatment, levels of alanine transaminase (ALT) and aspartate transaminase (AST) were detected by full-automatic biochemical analyzer. The level of blood urea nitrogen (BUN) was detected by the urease electrode method. The level of serum creatinine (Scr) was detected by the picric acid method. The levels of CD3 +, CD4 +, CD8 +, and NK cells were detected by BD FACSCalibur flow cytometer.
Results: There was no significant difference in clinical data between the two groups (P > 0.05). In the observation group, ORR was significantly higher than that in the control group (54.55% vs 29.55%) (P < 0.05), OS was significantly longer than that in the control group (P < 0.05), and median survival time and mPFS were longer than those in the control group. After treatment, the levels of ALT, AST, BUN, and Scr were significantly increased in the control group (P < 0.05), but there was no significant difference in peripheral blood CD3 +, CD4 +, and CD4 +/CD8 + ratio or count of NK cells before and after treatment (P > 0.05). Before and after treatment, there was no significant difference in the levels of ALT, AST, BUN, and Scr in the observation group (P > 0.05). After treatment, peripheral blood CD3 +, CD4 +, and CD4 +/CD8 + ratio and count of NK cells were all increased in the observation group, significantly higher than those in the control group (P < 0.05). The incidence of chemotherapy side effects in the observation group was significantly lower than that in the control group (P < 0.05).
Conclusion: The short-term and long-term curative effects of deep hyperthermia combined with intraperitoneal chemotherapy are good on patients with intraperitoneal metastases, with less damage to liver-kidney function. It is beneficial to enhance immune function of patients, with mild side effects.
Nasal bone is a long, paired series of small bones, which is narrow at the top and broad at the bottom, that forms the base of the nasal dorsum. Together with the nasal part of the frontal bone, the frontal process of the maxilla and the middle plate of the ethmoid bone constitute the bone scaffold of the external nose. In this paper, the DICOM image data file was imported into the Mimics software for 3D reconstruction. At the same time, the Geomagic software was used for relevant image processing, and the finite element software ANSYS was used to establish a finite element model to analyze the stress characteristics of the nasomaxillary complex. Results. The maximum principal stress and maximum strain force at the lower segment of nasal bone and the junction of nasal bone and maxilla were relatively large. When the same external force acts on the lower segment of the nasal bone and the angle is 0° (sagittal force), the maximum principal stress and maximum strain force are the smallest. When the angle continues to increase, the maximum principal stress and maximum strain force continue to increase.
Objective: To explore the clinical effect and aesthetic evaluation of minimally invasive implant in the treatment of dentition defect.
Methods: From April 2020 to May 2021, 60 patients who received implant restoration were collected as the research objects. Randomly divided into minimally invasive surgery group (30 patients) and routine surgery group (30 patients). The postoperative antibiotic use time, pain disappearance time, swelling degree, and pain degree of the two groups were compared. Follow-up for one year, record and compare the success rate of implants and aesthetic evaluation of restoration between the two groups. The evaluation of patients' satisfaction with restoration was collected and compared.
Results: The operation time and antibiotic use time of patients in minimally invasive surgery group were significantly shorter than those in conventional surgery group, and the swelling degree rating was significantly better than that in conventional surgery group, with statistical significance (P < 0.05). The number of patients with no pain (0 degree) and mild pain (degree) in minimally invasive surgery group was significantly higher than that in routine surgery group, and the difference was statistically significant (P < 0.05). One year after the repair, the success rate of implants in minimally invasive surgery group was 100.00% compared with that in routine surgery group (93.33%), and the difference was not statistically significant (P > 0.05). The aesthetic effect scores of patients in minimally invasive surgery group were higher than those in routine surgery group in seven items: proximal gingival papilla, distal gingival papilla, labial gingival margin curvature, labial gingival margin height, root convexity, soft tissue color, and soft tissue texture, with statistical significance (P < 0.05). The satisfaction scores of the patients in minimally invasive surgery group in chewing function, comfort, aesthetics, retention function, and language function were higher than those in conventional surgery group, and the differences were statistically significant (P < 0.05).
Conclusion: Minimally invasive implant can achieve the same effect as conventional implant, and it has the advantages of lower postoperative swelling, shorter pain time, better aesthetic effect, and higher satisfaction after restoration.
Acute intestinal obstruction (AIO) is one of the most common surgical acute abdomens. Emergency green channel refers to a fast and efficient service system provided by hospitals for critically ill patients. It is the key to ensure that emergency patients receive timely, standardized, efficient and thoughtful medical services, improve the success rate of rescue, and reduce medical risks. Acute intestinal obstruction is mainly treated by surgery in the clinic. Previous reports have shown that the application of different nursing methods in the operation of acute intestinal obstruction has different effects on the results of surgical treatment. In this study, the clinical data of 80 patients with AIO were retrospectively analyzed to explore the value of humanistic care under the emergency green channel in promoting the recovery of gastrointestinal function after AIO surgery.
Background: Implementation of emergency endovascular aortic repair provides an attractive opportunity in the treatment of complicated acute aortic syndromes involving descending aorta.
Aim: The aim of this study was to analyze the effectiveness of thoracic endovascular aortic repair (TEVAR) for the treatment of acute surgical emergencies involving the descending thoracic aorta.
Methods: A retrospective review of the medical records of all patients undergoing TEVAR in a single center since 2007 was undertaken. Patients with the aortic disease treated on emergency inclusion criteria were complicated spontaneous acute aortic syndrome (csAAS), traumatic aortic acute injuries (TAIs), and other indications requiring emergent intervention. Technical and clinical success with patient mortality, survival, and reoperation rate was evaluated according to Society for Vascular Surgery reporting standards for thoracic endovascular aortic repair (TEVAR).
Results: The emergency interventions were necessary in 74 cases (51.0%), including patients with the complicated spontaneous acute aortic syndrome (csAAS) (64.8%; n = 48) and traumatic aortic acute injuries (TAIs) (31.1%). In addition, in one case aortic iatrogenic dissection (AID) and in 2 other fistulas after the previous stent graft, implantations were diagnosed. All procedures were done through surgically exposed femoral arteries while 2 hybrid procedures required additional approaches. The primary technical success rate was 95.9%, in 3 cases endoleak was reported. The primary clinical success occurred in 94.5%. All patients survived the endovascular interventions, whereas during in-hospital stay one of them died due to multiorgan failure (early mortality 1.3%). During the follow-up period, lasting 6 through 164 months (median 67), 11 patients died. Annual, five- and ten-year probability of survival was 86.4 ± 0.04%, 80.0 ± 0.05%, and 76.6 ± 0.06%, respectively. However, the rate of 5-year survivors was significantly higher after TAI (95.2%) than scAAS (63.4%) (p=0.008). Early after the procedure, one individual developed transient paraparesis (1.3%). No other serious stent-graft-related adverse events were noted within the postdischarge follow-up period.
Conclusions: Descending aortic pathologies requiring emergent interventions can be treated by endovascular techniques with optimal results and low morbidity and mortality in an experienced and dedicated team.
[This retracts the article DOI: 10.1155/2022/3336880.].
[This retracts the article DOI: 10.1155/2022/3374780.].
[This retracts the article DOI: 10.1155/2022/7879633.].