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Surge Capacity of Taipei’s Regional Emergency Medical System during COVID-19: A System Dynamics Approach COVID-19 期间台北地区紧急医疗系统的突发能力:系统动力学方法
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-03-14 DOI: 10.1155/2024/5524382
Chih Chang Chen, Su Ying Hung
Background. The community transmission of COVID-19 has caused the breakdown of the regional emergency medical system (REMS), impacting the rights and care of regional patients with acute and severe conditions. This study proposes a model for the surge capacity of REMS to plan for readiness and preparedness during challenging events that overload capacity. Methods. The surge capacity of REMS during the COVID-19 pandemic was studied. The data collection included 26 hospitals that received the data. To simulate the dynamics of Taipei’s REMS surge capacity, we observed its ability to treat COVID-19 patients with moderate to severe acute respiratory distress syndrome (ARDS). This will involve monitoring the stock of ventilators, physicians, and nurses within the subsystem loops. Results. Healthcare managers and administrators can use the overload model and hypothetical scenarios to develop new scenarios with different demands on surge capacity. The REMS system capacity model can be used as an aid to guide planning and cross-checking for address Prepare to plan. Conclusions. We combined data regarding the availability of ventilators, physicians, nurses, specialized beds, and general acute care beds in our simulations. Thus, our simulations, with support from a well-established regional command and management structure, could help REMS achieve the optimal surge capacity.
背景。COVID-19 在社区的传播导致地区紧急医疗系统(REMS)瘫痪,影响了地区急重症患者的权益和护理。本研究提出了一个区域紧急医疗系统快速反应能力模型,以便在能力超负荷的挑战性事件中做好准备和规划。方法。研究了 COVID-19 大流行期间急诊急救系统的激增能力。数据收集包括 26 家接收数据的医院。为模拟台北市急救医疗系统激增能力的动态变化,我们观察了其治疗 COVID-19 中度至重度急性呼吸窘迫综合症(ARDS)患者的能力。这将涉及监测子系统循环中呼吸机、医生和护士的库存。结果。医疗保健管理人员和行政人员可以利用超负荷模型和假设情景,开发出对激增能力有不同需求的新情景。REMS 系统容量模型可用作指导规划和交叉检查地址准备计划的辅助工具。结论。我们在模拟中结合了有关呼吸机、医生、护士、专科病床和普通急诊病床可用性的数据。因此,在完善的地区指挥和管理结构的支持下,我们的模拟可以帮助 REMS 达到最佳的增援能力。
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引用次数: 0
The Predictive Role of Lactate in the Emergency Department in Patients with Severe Dyspnea 急诊科乳酸对严重呼吸困难患者的预测作用
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-02-29 DOI: 10.1155/2024/6624423
Maciej Niczewski, Szymon Gawęda, Paulina Kluszczyk, Mikołaj Rycerski, Daria Syguła, Anna Danel, Szymon Szmigiel, Konrad Mendrala, Aleksandra Oraczewska, Czarosław Kijonka, Monika Nowicka, Michał Wita, Tomasz Cyzowski, Grzegorz Brożek, Maciej Dyrbuś, Szymon Skoczyński
Objective. An accurate identification of patients at the need for prioritized diagnostics and care are crucial in the emergency department (ED). Blood gas (BG) analysis is a widely available laboratory test, which allows to measure vital parameters, including markers of ventilation and perfusion. The aim of our analysis was to assess whether blood gas parameters in patients with dyspnea at an increased risk of respiratory failure admitted to the ED can predict short-term outcomes. Methods. The study group eventually consisted of 108 patients, with available BG analysis. The clinical and laboratory parameters were retrospectively evaluated, and three groups were distinguished—arterial blood gas (ABG), venous blood gas (VBG), and mixed blood gas. The primary endpoint was short-term, all-cause mortality during the follow-up of median (quartile 1–quartile 3) 2 (1–4) months. The independent risk factors for mortality that could be obtained from blood gas sampling were evaluated. Results. The short-term mortality was 35.2% (38/108). Patients who died were more frequently initially assigned to the red triage risk group, more burdened with comorbidities, and the median SpO2 on admission was significantly lower than in patients who survived the follow-up period. In the multivariable analysis, lactate was the strongest independent predictor of death, with 1 mmol/L increasing all-cause mortality by 58% in ABG (95% CI: 1.01–2.47), by 80% in VBG (95% CI: 1.13–2.88), and by 68% in the mixed blood gas analysis (95% CI: 1.22–2.31), what remained significant in VBG and mixed group after correction for base excess. In each group, pH, pO2, and pCO2 did not predict short-term mortality. Conclusions. In patients admitted to the ED due to dyspnea, at risk of respiratory failure, lactate levels in arterial, venous, and mixed blood samples are independent predictors of short-term mortality.
目的。在急诊科(ED)中,准确识别需要优先诊断和护理的病人至关重要。血气(BG)分析是一种广泛使用的实验室检测方法,可测量包括通气和灌注指标在内的生命参数。我们分析的目的是评估急诊科收治的呼吸困难患者中呼吸衰竭风险较高者的血气参数是否能预测短期预后。研究方法研究小组最终由 108 名可进行血气分析的患者组成。对临床和实验室参数进行了回顾性评估,并分为三组--动脉血气(ABG)、静脉血气(VBG)和混合血气。主要终点是随访中位数(1分位数-3分位数)2(1-4)个月期间的短期全因死亡率。评估了从血气采样中获得的导致死亡的独立风险因素。结果显示短期死亡率为 35.2%(38/108)。死亡患者最初多被分到红色分诊风险组,合并症较多,入院时的中位SpO2明显低于随访期间存活的患者。在多变量分析中,乳酸是预测死亡的最强独立指标,在 ABG(95% CI:1.01-2.47)、VBG(95% CI:1.13-2.88)和混合血气分析(95% CI:1.22-2.31)中,1 毫摩尔/升乳酸会使全因死亡率增加 58%,在 VBG 和混合组中,校正碱过量后仍有显著意义。在各组中,pH、pO2 和 pCO2 都不能预测短期死亡率。结论对于因呼吸困难而被送入急诊室、有呼吸衰竭风险的患者,动脉、静脉和混合血液样本中的乳酸水平是短期死亡率的独立预测因子。
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引用次数: 0
Comparison of Clinical Characteristics, Therapy, and Short-Term Prognosis between Blunt and Penetrating Abdominal Trauma: A Multicentric Retrospective Cohort Study 钝性腹部创伤与穿透性腹部创伤的临床特征、治疗和短期预后比较:多中心回顾性队列研究
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-02-13 DOI: 10.1155/2024/5215977
Yi Liu, Yunhe Gao, Zhida Chen, Jianxin Cui, Wenquan Liang, Ze Wang, Linde Sun, Chuan Pang, Yuan Lv, Guoxiao Liu, Tingting Lu, Gan Zhang, Xiaoyu Dong, Hong Xu, Sheng Yao, Feng Liang, Gang Liu, Gang Chen, Jianmiao He, Wentong Xu, Bo Wei, Hongqing Xi, Lin Chen
Objective. Large-scale studies on the characteristics and management of abdominal trauma in megacities in China are lacking. The aim of this study was to analyze and present the clinical patterns and treatment status of abdominal trauma in regional medical centers. Methods. Cases of abdominal trauma treated at seven medical centers in Beijing from 2010 to 2021 were collected. Clinical information about age, sex, injury cause, geographic distribution, abbreviated injury scale/injury severity score (AIS/ISS) value, injury-hospital time, preoperative time, surgically identified organ injuries, type of surgery, causes of reoperation and 90-day mortality was included in this study. Clinical characteristics, treatment methods, and short-term prognoses (90-days survival) were compared between blunt abdominal trauma (BAT) and penetrating abdominal trauma (PAT) cases. Non-normally distributed data are described as medians (IQR), and the Mann‒Whitney U test was performed; qualitative data were analyzed using the test. Univariate and multivariate survival analyses were performed by the Cox proportional hazards model. Results. A total of 553 patients (86.98% male) with a median age of 36.50 (27.00–48.00) years were included. The BAT group had a significantly higher proportion of serious injury (), lower initial hemoglobin level (
目的。中国特大城市腹部创伤的特点和处理缺乏大规模研究。本研究旨在分析和介绍区域医疗中心腹部创伤的临床模式和治疗状况。方法。收集 2010 年至 2021 年北京 7 家医疗中心收治的腹部创伤病例。研究包括年龄、性别、受伤原因、地理分布、缩写损伤量表/损伤严重程度评分(AIS/ISS)值、受伤住院时间、术前时间、手术确定的器官损伤、手术类型、再次手术原因和 90 天死亡率等临床信息。比较了钝性腹部创伤(BAT)和穿透性腹部创伤(PAT)病例的临床特征、治疗方法和短期预后(90 天存活率)。非正态分布数据以中位数(IQR)表示,并进行曼-惠特尼 U 检验;定性数据采用该检验进行分析。采用 Cox 比例危险度模型进行单变量和多变量生存分析。结果共纳入 553 名患者(86.98% 为男性),中位年龄为 36.50(27.00-48.00)岁。与 PAT 组相比,BAT 组的严重损伤比例明显更高(),初始血红蛋白水平更低(1),腹腔镜手术率更低()。此外,更多的 BAT 病例来自北京周边地区(),受伤后的区域住院时间更长(10.47(5.18-22.51)小时对 7.00(3.80-15.38)小时)。在空腔脏器损伤亚组中,与 PAT 组相比,BAT 组的损伤-区域住院时间和术前时间明显更长(损伤-区域住院时间:10.23 (6.00-21.59) 小时 vs. 7.07 (3.99-13.85) 小时;术前时间:3.02 (2.01-5.01) 小时 vs. 7.00 (3.80-15.38) 小时):术前时间:3.02(2.01-5.58)小时 vs. 2.81(1.85-3.63)小时)。90天的总死亡率为11.9%,较长的受伤区域住院时间(HR:1.01,95% CI:1.00-1.02,)、接受重症监护室治疗(HR:4.69,95% CI:2.54-8.65,)和严重的ISS(ISS > 25 vs. ISS < 16,HR:2.78,95% CI:1.38-5.601,)对存活率的影响更大。结论是更多的 BAT 患者被转到更高级别的医院,导致院前和术前时间明显延长。在血流动力学稳定的亚组中,更多的 BAT 患者出现空腔脏器损伤。对这些患者来说,积极的腹腔镜诊断性探查可能是有益的。损伤与区域住院时间间隔较长、需要重症监护室护理和损伤严重程度评分(ISS)较高的患者预后较差。
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引用次数: 0
Strategies for Oxygen Ecosystems in Middle-Income Countries: A Review and Case Study from Lebanon 中等收入国家氧气生态系统战略:黎巴嫩的回顾与案例研究
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-02-02 DOI: 10.1155/2024/9964636
Tim Baker, Claudio Gatti, Guido Rossini, Habtamu Tolla, Anne Detjen, Mulugeta Mideksa, Nadeen Hilal, Rima Shaya
The COVID-19 pandemic led to a surge of critically ill patients and a sudden increase in the need for oxygen treatment worldwide. Pre-existing gaps in oxygen systems became apparent, and governments, multilateral agencies, and other partners scrambled to increase the production, supply, and use of oxygen to meet this need. The importance of an oxygen ecosystem that is appropriate for the local context became clear. This review describes strategies for oxygen ecosystems in middle-income countries, with specific experiences from Lebanon, following the authors’ extensive assessment of the country’s oxygen ecosystem, on behalf of the government and UNICEF. In the assessment, fifteen governmental hospitals were visited and evaluated using the UNICEF Oxygen System Planning Tool, discussions were held with key stakeholders, and documents were reviewed. An optimal oxygen ecosystem needs to take into consideration the production of oxygen and delivery to facilities, the maintenance system within facilities, and the clinical use of oxygen. Lebanon, a lower-middle income country in the Middle East, is contending with an extensive economic crisis affecting the health system. Eighteen recommendations for strengthening the oxygen ecosystem in Lebanon that are relevant for other middle-income countries include the establishment of a National Oxygen Committee, installation of additional oxygen plants, strengthened systems for maintenance and electricity supply, increased production, procurement and supply chain resilience, improved training and human resources, the use of data collection and regular information to guide the ecosystem, and integration of oxygen into the rest of the health system.
COVID-19 大流行导致危重病人激增,全球对氧气治疗的需求骤增。氧气系统先前存在的缺口变得显而易见,各国政府、多边机构和其他合作伙伴争相增加氧气的生产、供应和使用,以满足这一需求。建立一个适合当地情况的氧气生态系统的重要性显而易见。在作者代表黎巴嫩政府和联合国儿童基金会对该国的氧气生态系统进行广泛评估后,本综述介绍了中等收入国家氧气生态系统的战略,以及黎巴嫩的具体经验。在评估过程中,作者走访了 15 家政府医院,并使用联合国儿童基金会氧气系统规划工具进行了评估,与主要利益相关者进行了讨论,并查阅了相关文件。最佳的氧气生态系统需要考虑到氧气的生产和向医疗机构的输送、医疗机构内的维护系统以及氧气的临床使用。黎巴嫩是中东地区的一个中低收入国家,正在应对一场影响卫生系统的广泛经济危机。关于加强黎巴嫩氧气生态系统的 18 项建议对其他中等收入国家也有借鉴意义,其中包括建立国家氧气委员会,安装更多氧气设备,加强维护和电力供应系统,提高生产、采购和供应链的适应能力,改善培训和人力资源,利用数据收集和定期信息指导生态系统,以及将氧气纳入卫生系统的其他部分。
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引用次数: 0
Retracted: Effect of miR-144-3p-Targeted Regulation of PTEN on Proliferation, Apoptosis, and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells under Stretch. 撤回:miR-144-3p靶向调控PTEN对拉伸条件下骨髓间充质干细胞增殖、凋亡和成骨分化的影响
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-01-24 eCollection Date: 2024-01-01 DOI: 10.1155/2024/9820745
Emergency Medicine International

[This retracts the article DOI: 10.1155/2022/5707504.].

[本文撤回了文章 DOI:10.1155/2022/5707504.]。
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引用次数: 0
Retracted: Value of Humanized Nursing under Emergency Green Channel on Gastrointestinal Function Recovery in Patients with Acute Intestinal Obstruction after Operation. 撤回:急诊绿色通道下的人性化护理对术后急性肠梗阻患者胃肠功能恢复的价值
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-01-24 eCollection Date: 2024-01-01 DOI: 10.1155/2024/9768409
Emergency Medicine International

[This retracts the article DOI: 10.1155/2023/2303766.].

[本文撤回了文章 DOI:10.1155/2023/2303766.]。
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引用次数: 0
Our Surgical Results in Popliteal and Infrapopliteal Artery Injuries: 21 Cases without Amputation 腘动脉和腘下动脉损伤的手术效果:21 例未截肢病例
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-01-24 DOI: 10.1155/2024/1721047
Burak Tamteki̇n, Güler Gülsen Ersoy
Objectives. Popliteal and infrapopliteal artery injuries have significant morbidity and mortality rates, especially in terms of amputation. In our study, we aimed to evaluate patients who operated due to popliteal and infrapopliteal vascular injuries in our clinic. Patients and Methods. Between 2016 and 2023; 21 patients who were operated in our clinic due to popliteal and infrapopliteal artery injuries were retrospectively evaluated. Results. 2 of the patients were female (9.5%) and 19 were male (90.5%). Age ranges were 21–78. The causes of injury were gunshot wounds in 9 patients (42.86%), blunt trauma in 7 patients (33.33%), and sharp object injuries in 5 patients (23.80%). Reversed saphenous vein interposition in 7 patients (33.33%), primary repair in 6 patients (28.57%), 6 mm polytetrafluoroethylene graft (PTFE) interposition in 3 patients (14.28%), end-to-end anastomosis in 2 patients (9.52%), saphenous-PTFE composite graft interposition in 2 patients (9.52%), and embolectomy in 1 patient (4.76%) were performed. Arterial ligation was not performed. Simultaneous orthopedic intervention was performed in 8 patients. Fasciotomy was performed in 3 patients. Venous repair was performed in 5 patients with venous injuries. Vein ligation was not performed. Mortality was observed postoperatively in 1 patient. No patient developed amputation. Foot drop developed with nerve damage in 2 patients. Conclusion. Mortality and morbidity rates may increase in popliteal and infrapopliteal artery injuries in cases of hemodynamic disorder, simultaneous bone fracture, multivessel injury, and nerve transection. These rates can be reduced by appropriate surgical repair and ensuring hemodynamic stability.
目的。腘动脉和腘下动脉损伤具有显著的发病率和死亡率,尤其是截肢。在我们的研究中,我们旨在评估在本诊所因腘动脉和腘下动脉血管损伤而进行手术的患者。患者和方法。回顾性评估2016年至2023年期间在本诊所因腘动脉和腘下动脉损伤而接受手术的21例患者。结果2名患者为女性(9.5%),19名患者为男性(90.5%)。年龄介于 21-78 岁之间。受伤原因分别为枪伤 9 例(42.86%)、钝器伤 7 例(33.33%)和锐器伤 5 例(23.80%)。7 名患者(33.33%)进行了大隐静脉反向插植术,6 名患者(28.57%)进行了初级修复术,3 名患者(14.28%)进行了 6 毫米聚四氟乙烯(PTFE)移植物插植术,2 名患者(9.52%)进行了端对端吻合术,2 名患者(9.52%)进行了大隐-PTFE 复合移植物插植术,1 名患者(4.76%)进行了栓子切除术。未进行动脉结扎手术。8 名患者同时进行了骨科干预。3 名患者进行了筋膜切开术。5名静脉损伤患者进行了静脉修复。未进行静脉结扎手术。1 名患者术后死亡。没有患者截肢。2 名患者出现足下垂并伴有神经损伤。结论在血液动力学紊乱、同时骨折、多血管损伤和神经横断的情况下,腘动脉和腘下动脉损伤的死亡率和发病率可能会增加。通过适当的手术修复并确保血液动力学稳定,可以降低死亡率和发病率。
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引用次数: 0
Point-of-Care Cardiac Ultrasound Training Programme: Experience from the University Hospital Hradec Králové 护理点心脏超声培训计划:赫拉德茨-克拉洛韦大学医院的经验
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-01-06 DOI: 10.1155/2024/9974284
Petr Grenar, Jiří Nový, Karel Mědílek, Martin Jakl
Point-of-care ultrasound examinations performed by physicians of different specialties are a rapidly growing phenomenon, which has led to a worldwide effort to create a standardised approach to ultrasound examination training. The implementation of emergency echocardiography by noncardiologists is mainly aimed at the standardisation of the procedure, a structured training system, and an agreement on competencies. This article summarises the current training programmes for nonechocardiographers at the University Hospital in Hradec Králové. In cooperation with cardiologists specialised in cardiac ultrasound (ECHO), an extended acute echo protocol dedicated to emergency department physicians was developed and validated in daily practice. According to our retrospective evaluation, after one year of clinical practice, we can confirm that point-of-care ultrasound examinations performed using the standardised limited echo protocol are safe and accurate. The observed concordance with comprehensive ECHO was 78%. This trial is registered with NCT05306730.
由不同专业的医生进行床旁超声检查是一种迅速发展的现象,这促使全世界都在努力创造一种标准化的超声检查培训方法。由非心内科医师实施急诊超声心动图检查的主要目的是实现程序标准化、建立结构化的培训系统并就能力达成一致。本文总结了赫拉德茨-克拉洛韦大学医院目前对非心内科医师的培训计划。我们与心脏超声(ECHO)专业的心脏病专家合作,为急诊科医生制定了一个扩展的急性回声检查方案,并在日常实践中进行了验证。根据我们的回顾性评估,经过一年的临床实践,我们可以确认使用标准化有限回波方案进行的护理点超声检查是安全和准确的。观察到的与综合 ECHO 的一致性为 78%。该试验已在 NCT05306730 上注册。
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引用次数: 0
Clinical Features and Biomarkers for Early Prediction of Refractory Mycoplasma Pneumoniae Pneumonia in Children 用于早期预测儿童难治性肺炎支原体肺炎的临床特征和生物标志物
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-01-05 DOI: 10.1155/2024/9328177
Qin Chen, Tingting Hu, Ling Wu, Lumin Chen
Summary of Background Data.With the increasing incidence and mortality of refractory mycoplasma pneumonia (RMPP), the early diagnosis and treatment of RMPP have attracted more and more attention and have become a major concern in pediatrics. Objective. The study aimed to analyze the clinical characteristics of children with RMPP and to explore the biomarkers for the early prediction of RMPP, thus providing references for the clinical diagnosis and treatment of RMPP in children. Methods. Baseline clinical characteristics, clinical symptoms, physical examination, chest imaging, and laboratory indicators between children with RMPP and general refractory mycoplasma pneumoniae pneumonia (GMPP) were compared. Multiple logistic regression analysis was used to determine independent risk factors for RMPP. ROC curves were adopted to analyze the predictive values of biomarkers. Results. The RMPP group had more severe clinical symptoms and manifestations on imaging (including pleural effusion, pulmonary consolidation, and pulmonary atelectasis), a higher incidence of extrapulmonary complications, and a longer duration of hospital stays. Results of multiple logistic regression analysis showed that serum D-dimer (OR = 8.169, ), C-reactive protein (CRP) (OR = 1.146,
背景资料摘要:随着难治性支原体肺炎(RMPP)发病率和死亡率的不断上升,RMPP 的早期诊断和治疗已引起越来越多的关注,并已成为儿科领域的一个重要问题。研究目的本研究旨在分析 RMPP 患儿的临床特征,探讨早期预测 RMPP 的生物标志物,从而为儿童 RMPP 的临床诊断和治疗提供参考。研究方法比较RMPP患儿和一般难治性肺炎支原体肺炎(GMPP)患儿的基线临床特征、临床症状、体格检查、胸部影像学检查和实验室指标。采用多元逻辑回归分析确定 RMPP 的独立危险因素。采用ROC曲线分析生物标志物的预测价值。结果RMPP组的临床症状和影像学表现(包括胸腔积液、肺部合并症和肺不张)更严重,肺外并发症的发生率更高,住院时间更长。多元逻辑回归分析结果显示,血清 D-二聚体(OR = 8.169,)、C 反应蛋白(CRP)(OR = 1.146,)和乳酸脱氢酶(LDH)(OR = 1.025,)水平是 RMPP 的独立危险因素。D-二聚体、CRP和LDH血清水平预测RMPP的接收者操作特征曲线下面积(AUROC)分别为0.841、0.870和0.893(),临界值分别为1.47纳克/毫升、39.34毫克/升和379 IU/升。结论血清D-二聚体、CRP和LDH水平与儿童肺炎支原体肺炎的严重程度有关,有可能成为早期预测RMPP的生物标志物,对临床早期诊断和及时干预RMPP患儿具有重要的应用价值。
{"title":"Clinical Features and Biomarkers for Early Prediction of Refractory Mycoplasma Pneumoniae Pneumonia in Children","authors":"Qin Chen, Tingting Hu, Ling Wu, Lumin Chen","doi":"10.1155/2024/9328177","DOIUrl":"https://doi.org/10.1155/2024/9328177","url":null,"abstract":"<i>Summary of Background Data</i>.With the increasing incidence and mortality of refractory mycoplasma pneumonia (RMPP), the early diagnosis and treatment of RMPP have attracted more and more attention and have become a major concern in pediatrics. <i>Objective</i>. The study aimed to analyze the clinical characteristics of children with RMPP and to explore the biomarkers for the early prediction of RMPP, thus providing references for the clinical diagnosis and treatment of RMPP in children. <i>Methods</i>. Baseline clinical characteristics, clinical symptoms, physical examination, chest imaging, and laboratory indicators between children with RMPP and general refractory mycoplasma pneumoniae pneumonia (GMPP) were compared. Multiple logistic regression analysis was used to determine independent risk factors for RMPP. ROC curves were adopted to analyze the predictive values of biomarkers. <i>Results</i>. The RMPP group had more severe clinical symptoms and manifestations on imaging (including pleural effusion, pulmonary consolidation, and pulmonary atelectasis), a higher incidence of extrapulmonary complications, and a longer duration of hospital stays. Results of multiple logistic regression analysis showed that serum D-dimer (OR = 8.169, <span><svg height=\"9.2729pt\" style=\"vertical-align:-0.6370001pt\" version=\"1.1\" viewbox=\"-0.0498162 -8.6359 19.289 9.2729\" width=\"19.289pt\" xmlns=\"http://www.w3.org/2000/svg\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"><g transform=\"matrix(.013,0,0,-0.013,0,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,11.658,0)\"></path></g></svg><span></span><span><svg height=\"9.2729pt\" style=\"vertical-align:-0.6370001pt\" version=\"1.1\" viewbox=\"22.8711838 -8.6359 28.182 9.2729\" width=\"28.182pt\" xmlns=\"http://www.w3.org/2000/svg\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"><g transform=\"matrix(.013,0,0,-0.013,22.921,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,29.161,0)\"></path></g><g transform=\"matrix(.013,0,0,-0.013,32.125,0)\"><use xlink:href=\"#g113-49\"></use></g><g transform=\"matrix(.013,0,0,-0.013,38.365,0)\"><use xlink:href=\"#g113-49\"></use></g><g transform=\"matrix(.013,0,0,-0.013,44.605,0)\"></path></g></svg>),</span></span> C-reactive protein (CRP) (OR = 1.146, <span><svg height=\"9.2729pt\" style=\"vertical-align:-0.6370001pt\" version=\"1.1\" viewbox=\"-0.0498162 -8.6359 19.289 9.2729\" width=\"19.289pt\" xmlns=\"http://www.w3.org/2000/svg\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"><g transform=\"matrix(.013,0,0,-0.013,0,0)\"><use xlink:href=\"#g113-81\"></use></g><g transform=\"matrix(.013,0,0,-0.013,11.658,0)\"><use xlink:href=\"#g117-91\"></use></g></svg><span></span><span><svg height=\"9.2729pt\" style=\"vertical-align:-0.6370001pt\" version=\"1.1\" viewbox=\"22.8711838 -8.6359 28.182 9.2729\" width=\"28.182pt\" xmlns=\"http://www.w3.org/2000/svg\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"><g transform=\"matrix(.013,0,0,-0.013,22.921,0)\"><use xlink:href=\"#g113-49\"></use></g><g transform=\"matrix(.013,0,0,-0.013,29.161,0)\"><use xlink:href=","PeriodicalId":11528,"journal":{"name":"Emergency Medicine International","volume":"16 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139104816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence, Risk Factors, and Mortality of Patients Presenting with Moderate and Severe Hyponatremia in Emergency Departments 急诊科中度和重度低钠血症患者的患病率、风险因素和死亡率
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2023-12-31 DOI: 10.1155/2023/9946578
Randa Farah, Nisreen Asha, Farah Mezher, Saja Maaitah, Fedaa Abu Al-Samen, Farah Abu Abboud, Salma Ajarmeh
<i>Background</i>. Hyponatremia is among the most common electrolyte disturbances encountered in clinical practice and is associated with a high rate of morbidity and mortality. However, there are very limited data on adult cases presenting to emergency departments with hyponatremia. <i>Objectives</i>. This study aimed to evaluate the frequency, clinical characteristics, and outcomes in hyponatremic patients presenting to emergency departments. <i>Methods</i>. This retrospective study analyzed all patients older than 18 years who visited our institution’s emergency department between October 2018 and October 2019 and has a serum sodium (Na) level <130 mmol/L. <i>Results</i>. Among 24,982 patients who visited the emergency department and had a documented serum sodium level, 284 were included. Patients’ median age was 67.13 ± 14.8 years. Younger patients are less likely to develop severe hyponatremia compared to older patients (adjusted odds ratio (AOR): 0.415; 95% confidence interval (CI): 0.231–0.743; <span><svg height="11.7782pt" style="vertical-align:-3.42938pt" version="1.1" viewbox="-0.0498162 -8.34882 18.973 11.7782" width="18.973pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"></path></g><g transform="matrix(.013,0,0,-0.013,11.342,0)"></path></g></svg><span></span><span><svg height="11.7782pt" style="vertical-align:-3.42938pt" version="1.1" viewbox="22.555183800000002 -8.34882 28.184 11.7782" width="28.184pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,22.605,0)"></path></g><g transform="matrix(.013,0,0,-0.013,28.845,0)"></path></g><g transform="matrix(.013,0,0,-0.013,31.809,0)"><use xlink:href="#g113-49"></use></g><g transform="matrix(.013,0,0,-0.013,38.049,0)"><use xlink:href="#g113-49"></use></g><g transform="matrix(.013,0,0,-0.013,44.289,0)"></path></g></svg>).</span></span> Asymptomatic hyponatremia and gastrointestinal manifestations were the most common presenting hyponatremia symptoms (33.7% and 24.2%, respectively). Proton pump inhibitor (PPI) use, angiotensin-converting enzyme inhibitor/angiotensin receptor blocker (ACE/ARB) use, and spironolactone use (OR = 2.6 and 3.9, 2.3 with a <span><svg height="11.7782pt" style="vertical-align:-3.42938pt" version="1.1" viewbox="-0.0498162 -8.34882 18.973 11.7782" width="18.973pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><use xlink:href="#g113-113"></use></g><g transform="matrix(.013,0,0,-0.013,11.342,0)"><use xlink:href="#g117-34"></use></g></svg><span></span><span><svg height="11.7782pt" style="vertical-align:-3.42938pt" version="1.1" viewbox="22.555183800000002 -8.34882 21.921 11.7782" width="21.921pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,22.605,0)"><use xlink:href="#g113-49"></use></g><
背景。低钠血症是临床上最常见的电解质紊乱之一,发病率和死亡率都很高。然而,有关成人低钠血症急诊病例的数据非常有限。研究目的本研究旨在评估急诊科低钠血症患者的发病频率、临床特征和预后。方法。这项回顾性研究分析了2018年10月至2019年10月期间到我院急诊科就诊的所有18岁以上、血清钠(Na)水平为<130 mmol/L的患者。研究结果在 24982 名到急诊科就诊并有血清钠水平记录的患者中,有 284 人被纳入其中。患者的中位年龄为 67.13 ± 14.8 岁。与老年患者相比,年轻患者发生严重低钠血症的几率较低(调整后的几率比(AOR):0.415;95% 置信区间(CI):0.231-0.743;)。无症状性低钠血症和胃肠道表现是最常见的低钠血症症状(分别为 33.7% 和 24.2%)。使用质子泵抑制剂(PPI)、血管紧张素转换酶抑制剂/血管紧张素受体阻滞剂(ACE/ARB)和螺内酯(OR = 2.6 和 3.9,2.3,a , 0.03 和 0.05)与严重低钠血症的几率增加有关。重度和中度低钠血症组在发病后 6 个月内的总死亡率没有差异(11.1% 对 16.2%)。结论在急诊科就诊的患者中,中度和重度低钠血症并不少见。中度低钠血症可无症状,但有临床意义。与中度低钠血症相比,老年患者、使用 PPI、使用 ACEi/ARBs 和使用螺内酯与重度低钠血症的风险增加有关。要证实我们的研究结果,还需要对更多的人群进行进一步的前瞻性分析。
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引用次数: 0
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Emergency Medicine International
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