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Subdermal Plexus Density as It Relates to Obesity and Wound Complications in Patients Undergoing Reduction Mammaplasty. 真皮下神经丛密度与乳房缩小成形术患者肥胖和伤口并发症的关系。
Pub Date : 2023-01-01
Kathryn W Brown, Martin G McCandless, Hemanth Nannapaneni, Kristen Adams, Somjade Jay Songcharoen, Peter B Arnold

Background: Reduction mammaplasty is one of the most common reconstructive procedures performed in plastic surgery. Multiple comorbidities play a role in postoperative wound healing complications; however, there are insufficient data on the subdermal plexus (SDP) as it relates to these comorbidities. The purpose of this study is to evaluate the relationship between body mass index (BMI) and SDP of the superficial breast tissues and examine the association between SDP and postoperative complications.

Methods: After Institutional Review Board approval, screening, and informed consent, patients undergoing reduction mammaplasty were selected. Tissue to be discarded was sent to pathology for analysis of immunohistochemistry directed against endothelial cells to determine the density of the SDP. Patients with BMI <35 and ≥35 kg/m2 were compared. Statistical analysis, including 2-tailed t test and Pearson correlation, was conducted.

Results: A significant difference in SDP density (standard deviation) was identified between patients with a BMI ≥35 versus <35 kg/m2 (2.65 capillaries/mm2 ± 1.8 vs 1.56 capillaries/mm2 ± 1.2; P = .033). Patients with no historical use of tobacco versus those who used tobacco showed a significantly increased SDP (2.11 capillaries/mm2 ± 1.6 vs 1.20 capillaries/mm2 ± 0.5; P = .009). A significant relationship between postoperative infection (1.00 capillaries/mm2 ± 1.1; P = .041) and hematoma/seroma (0.788 capillaries/mm2 ± 0.1; P = .003) was identified. No significant relationship was found between SDP and delayed wound healing, nipple-areolar complex complications, fat/flap necrosis, or symptomatic scar occurrence.

Conclusions: There is a statistically significant increase in SDP seen with increasing BMI, which does not explain the higher rate of wound healing complications after reduction mammaplasty typically seen in the higher BMI patient population. The association between BMI and complications after reduction mammaplasty remains unclear.

背景:乳房缩小成形术是整形外科中最常见的重建手术之一。多种合并症在术后伤口愈合并发症中起作用;然而,关于真皮下神经丛(SDP)与这些合并症的关系的数据不足。本研究的目的是评估体重指数(BMI)与乳腺浅表组织SDP的关系,并探讨SDP与术后并发症的关系。方法:经机构审查委员会批准、筛选和知情同意后,选择接受缩小乳房成形术的患者。将丢弃的组织送到病理学处进行针对内皮细胞的免疫组织化学分析,以确定SDP的密度。比较BMI为2的患者。采用双尾t检验和Pearson相关进行统计学分析。结果:BMI≥35和2患者的SDP密度(标准差)存在显著差异(2.65毛细血管/mm2±1.8 vs 1.56毛细血管/mm2±1.2;P = .033)。无吸烟史的患者与有吸烟史的患者相比,SDP显著增加(2.11毛细血管/mm2±1.6 vs 1.20毛细血管/mm2±0.5;P = .009)。术后感染(1.00支毛细血管/mm2±1.1;P = 0.041)和血肿/血肿(0.788毛细血管/mm2±0.1;P = .003)。SDP与伤口延迟愈合、乳头-乳晕复杂并发症、脂肪/皮瓣坏死或症状性瘢痕发生之间无显著关系。结论:随着BMI的增加,SDP有统计学意义上的显著增加,这并不能解释高BMI患者群体中典型的乳房缩小成形术后伤口愈合并发症发生率较高的原因。BMI与缩乳术后并发症之间的关系尚不清楚。
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引用次数: 0
Case Report of Complete Second Branchial Fistula. 完全性第二鳃裂瘘1例报告。
Pub Date : 2023-01-01
Kaori Yauchi, Misato Ueda, Makoto Omori

Background: Branchial fistulas are anomalies of embryonic development of the branchial apparatus, with the most common being second branchial fistulas. However, complete fistulas are infrequent and may relapse. Furthermore, they are difficult to manage without adequate treatment.

Methods: This article presents the case of a complete second branchial fistula in a 1-year-old female patient who had a sinus on the right side of the neck since birth. Excision of the fistula tract was performed without preoperative fistulography. The tract was then ligated and dissected immediately below the mucosa.

Results: The postoperative course was uneventful, and there was no evidence of recurrence.

Conclusions: Previous case reports have also demonstrated good outcomes without excision of the internal opening or tonsillectomy.

背景:鳃裂瘘管是鳃裂器官胚胎发育的异常,最常见的是第二鳃裂瘘管。然而,完全性瘘管并不常见,而且可能复发。此外,如果没有适当的治疗,它们很难控制。方法:这篇文章提出了一个完整的第二鳃裂瘘管的情况下,1岁的女性患者谁有一个窦右颈部出生以来。术前未行瘘管造影,切除瘘管束。然后结扎并立即在粘膜下方剥离该束。结果:手术过程顺利,无复发迹象。结论:以前的病例报告也显示了不切除内开口或扁桃体切除术的良好结果。
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引用次数: 0
Comparison of Treatment Options for Chronic Scapholunate Interosseous Ligament (SLIL): A Systematic Literature Review and Meta-Analysis. 慢性舟月骨间韧带(sll)治疗方案的比较:系统文献综述和meta分析。
Pub Date : 2023-01-01
Kamil M Amer, Jennifer E Thomson, Samer T Elsamna, Dominick V Congiusta, Owen Gantz, Robert L DalCortivo, Michael M Vosbikian, Irfan H Ahmed

Background: The scapholunate interosseous ligament (SLIL) is an important contributor to wrist stability and functionality. SLIL injury is debilitating and therefore many surgical techniques have been proposed, but the optimal treatment modality remains debated.This meta-analysis reviews the available literature comparing surgical techniques used in the treatment of chronic SLIL to determine the best approach.

Methods: An electronic search of the literature was conducted to identify all randomized controlled trials and cohort studies published before January 2019 that evaluated clinical outcomes of capsulodesis reconstruction, the modified Brunelli technique, and the reduction and association of the scaphoid and lunate (RASL) procedure for treatment of chronic SLIL. A chi-square analysis was performed to identify possible differences between each technique for several outcome measures.

Results: A total 20 studies encompassing 409 patients met inclusion criteria. Average age among patients was 36.7 years, and 68.2% of patients were male. Reductions in visual analog scale pain scale; Disabilities of Arm, Shoulder, and Hand (DASH) scores; and increases in grip strength and range of motion were observed for all techniques. Capsulodesis was superior to the modified Brunelli technique regarding preserved range of motion.

Conclusions: No significant differences were observed among any of the techniques for pain, DASH score, and grip strength outcomes. Capsulodesis, modified Brunelli, and RASL surgical techniques for the treatment of chronic SLIL injuries may all be seen as reliable methods of treatment of chronic SLIL injuries. While future trials directly comparing these methods are needed, this study suggests there is no superiority of one technique over another.

背景:舟月骨间韧带(SLIL)是腕关节稳定和功能的重要贡献者。SLIL损伤使人衰弱,因此提出了许多手术技术,但最佳治疗方式仍存在争议。本荟萃分析回顾了现有文献,比较了用于治疗慢性sll的手术技术,以确定最佳方法。方法:对文献进行电子检索,以确定2019年1月之前发表的所有随机对照试验和队列研究,这些研究评估了囊膜固定术重建、改良Brunelli技术以及舟状骨和月骨复位联合(RASL)手术治疗慢性sll的临床结果。进行卡方分析以确定每种技术在若干结果测量方面可能存在的差异。结果:共有20项研究包括409例患者符合纳入标准。患者平均年龄36.7岁,男性占68.2%。视觉模拟疼痛量表降低;手臂、肩膀和手的残疾(DASH)分数;所有技术的握力和活动范围都有所增加。包膜固定术在保持关节活动范围方面优于改良Brunelli技术。结论:在疼痛、DASH评分和握力结果方面,没有观察到任何技术之间的显著差异。囊膜固定术、改良Brunelli和RASL手术技术治疗慢性sll损伤均可被视为治疗慢性sll损伤的可靠方法。虽然未来的试验需要直接比较这些方法,但这项研究表明,没有一种技术比另一种技术优越。
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引用次数: 0
Incidence, Etiology, and Risk Factors Associated with Foot Drop. 足下垂的发生率、病因和危险因素。
Pub Date : 2023-01-01
Rahul K Nath, Chandra Somasundaram

Background: Injury to the neurological pathway that enables ankle dorsiflexion is likely to cause foot drop. This pathway includes the motor cortex; lumbosacral plexus; and the sciatic, tibial, and peroneal nerves. Nerve damage typically occurs due to compression, entrapment, traction, or direct trauma to the nerve due to several etiologies. However, there are limited reports on the incidence, etiology, and factors associated with foot drop.

Methods: The authors reviewed their clinic's data from 1022 patients with foot drop from 2004 to present to determine the incidence, causes, and risk factors of foot drop. Microsoft Excel was used for descriptive statistical data analysis and graphing.

Results: A total of 21 causes of foot drop were found. Of 1022 patients, 142 (13.9%) had foot drop after lumbosacral (LS) spine surgery, while 131 patients (12.8%) with LS spine complications who had not undergone surgery also reported foot drop. The LS spine complications and surgeries were influenced by age (median age, 63 and 55 years, respectively) and were marginally higher in male patients (54%). A total of 79 patients (7.8%) with foot drop had previously undergone hip replacement surgery. Older age (median age, 60 years) and female sex (85%) were risk factors for hip replacement surgery resulting in foot drop. In contrast, younger age and male sex were the risk factors for gunshot and stab wounds, injection drug use, drug or medication overdoses, and motor vehicle accidents resulting in foot drop.

Conclusions: Failed back surgery syndrome is the leading cause of foot drop after lumbosacral spine and hip replacement surgeries in both male and female older (median age, 60 years) patients. However, most (85%) of the foot drop patients in the present study who underwent hip replacement surgery were female patients. Sports and recreational activities, motor vehicle accidents, drug use, and violence are common causes of foot drop in younger male adults.

背景:导致踝关节背屈的神经通路损伤很可能导致足下垂。这条通路包括运动皮层;腰骶神经丛;还有坐骨神经,胫神经和腓神经。神经损伤通常是由于压迫、卡压、牵引或由于几种病因引起的神经直接创伤而发生的。然而,关于足下垂的发生率、病因和相关因素的报道有限。方法:作者回顾了2004年至今1022例足下垂患者的临床资料,以确定足下垂的发生率、原因和危险因素。使用Microsoft Excel进行描述性统计数据分析和绘图。结果:共发现足下垂原因21种。1022例患者中,142例(13.9%)腰骶(LS)脊柱手术后出现足下垂,而131例(12.8%)腰骶(LS)脊柱并发症患者未接受手术也出现足下垂。LS脊柱并发症和手术受年龄影响(中位年龄分别为63岁和55岁),男性患者略高(54%)。79例(7.8%)足部下垂患者曾行髋关节置换术。老年(中位年龄60岁)和女性(85%)是髋关节置换术导致足下垂的危险因素。相比之下,年轻和男性是枪击和刺伤、注射吸毒、药物或药物过量以及机动车事故导致跌倒的危险因素。结论:在男性和女性老年(中位年龄60岁)患者中,背部手术失败综合征是腰骶椎和髋关节置换术后足下垂的主要原因。然而,在本研究中接受髋关节置换术的足下垂患者中,大多数(85%)是女性患者。体育和娱乐活动、机动车事故、吸毒和暴力是年轻男性跌倒的常见原因。
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引用次数: 0
Cultural Beliefs Regarding Breast Reconstruction in a Minority Group. 少数民族乳房再造的文化信仰。
Pub Date : 2023-01-01
Angela Li, Maria Alonso Luaces, Michelle De Souza

Background: The diagnosis and treatment of breast cancer can significantly affect a woman's health and well-being. Several studies have identified factors contributing to disparities in breast reconstruction among ethnic groups, but few have examined the experience of Hispanic women.

Methods: Hispanic women who had undergone breast reconstruction were interviewed in retrospective focus groups. Data were collected to identify themes that affected decision-making regarding the type and timing of reconstruction.

Results: Most participants chose to undergo reconstruction to regain normalcy and maintain their previous "feminine" appearance. Most (75%) received silicone breast implants, and 25% received autologous reconstruction. Safety was the most important consideration when choosing the type of reconstruction. All but 1 participant relied on a spouse or other family member for support during recovery. Although most found the experience overwhelming, they felt their community was supportive and encouraging throughout the process.

Conclusions: Several themes underlying the decision to undergo reconstruction were identified, including maintaining femininity and choosing the safest procedure. Overall, participants described the experience as overwhelming but found support from community and family. These findings, which could be applied broadly to women regardless of ethnicity, can be used to improve communication between surgeon and patient throughout the reconstruction process.

背景:乳腺癌的诊断和治疗可以显著影响女性的健康和幸福。有几项研究已经确定了导致不同种族乳房重建差异的因素,但很少有研究调查西班牙裔女性的经历。方法:采用回顾性焦点小组对接受乳房再造的西班牙裔妇女进行访谈。收集数据以确定影响重建类型和时间决策的主题。结果:大多数参与者选择接受重建,以恢复正常和保持他们以前的“女性”外观。大多数(75%)接受硅胶乳房植入物,25%接受自体乳房重建。在选择重建类型时,安全性是最重要的考虑因素。除1名参与者外,所有参与者在康复期间都依赖配偶或其他家庭成员的支持。虽然大多数人觉得这段经历让他们不堪重负,但他们觉得自己的社区在整个过程中都是支持和鼓励的。结论:确定了决定进行重建的几个主题,包括保持女性气质和选择最安全的手术。总的来说,参与者描述的经验是压倒性的,但找到了来自社区和家庭的支持。这些发现可以广泛应用于不分种族的女性,可以用来改善外科医生和患者在整个重建过程中的沟通。
{"title":"Cultural Beliefs Regarding Breast Reconstruction in a Minority Group.","authors":"Angela Li,&nbsp;Maria Alonso Luaces,&nbsp;Michelle De Souza","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The diagnosis and treatment of breast cancer can significantly affect a woman's health and well-being. Several studies have identified factors contributing to disparities in breast reconstruction among ethnic groups, but few have examined the experience of Hispanic women.</p><p><strong>Methods: </strong>Hispanic women who had undergone breast reconstruction were interviewed in retrospective focus groups. Data were collected to identify themes that affected decision-making regarding the type and timing of reconstruction.</p><p><strong>Results: </strong>Most participants chose to undergo reconstruction to regain normalcy and maintain their previous \"feminine\" appearance. Most (75%) received silicone breast implants, and 25% received autologous reconstruction. Safety was the most important consideration when choosing the type of reconstruction. All but 1 participant relied on a spouse or other family member for support during recovery. Although most found the experience overwhelming, they felt their community was supportive and encouraging throughout the process.</p><p><strong>Conclusions: </strong>Several themes underlying the decision to undergo reconstruction were identified, including maintaining femininity and choosing the safest procedure. Overall, participants described the experience as overwhelming but found support from community and family. These findings, which could be applied broadly to women regardless of ethnicity, can be used to improve communication between surgeon and patient throughout the reconstruction process.</p>","PeriodicalId":11687,"journal":{"name":"Eplasty","volume":"23 ","pages":"e45"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472427/pdf/eplasty-23-e45.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10152939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of an Autologous Heterogenous Skin Construct in the Treatment of Intractable Late-Effect Radiation Wounds: Case Series. 自体异质皮肤结构在治疗顽固性晚期放射伤中的应用:病例系列。
Pub Date : 2023-01-01
Diana Burgueno-Vega, Dilip Shahani, Walter Conlan, Melodie Blakely

Background: Late-effect radiation-induced wounds represent a particularly difficult category of wounds to manage and treat. Fibrosis, impaired cellular activity, ischemia, and wound chronicity all work to impair healing, and this becomes more pronounced when defects are large or when avascular structures such as bone are exposed. Effective treatment options for this type of wound are limited. Thorough excision of irradiated tissue followed by distal pedicled or free flap closure is the most successful; however, this often requires multiple-stage surgeries and prolonged hospitalization and is associated with significant donor site morbidity. This is complicated further when wounds are large or in difficult locations, when surgery is not appropriate, or when there is limited access to surgeons with the appropriate experience/skill to perform such procedures.

Methods: This case series describes the use of an autologous heterogenous skin construct (AHSC) made from a small full-thickness sample of the patient's healthy skin. Three patients with intractable late-effect radiation wounds were treated with AHSC. Case 1 describes an abdominal wound with tunneling of 7.5 cm to the pubic symphysis, which had been treated for known osteomyelitis, and a shallower full-thickness groin wound. Case 2 describes a right scapular wound with exposed bone, which had failed flap closure. Case 3 describes a right thigh wound in a patient who had been treated for sarcoma with extensive radiation therapy. This eventually resulted in an above-the-knee amputation, which failed to heal, and full exposure of the distal end of the resected femur. All wounds had been present for greater than 10 months.

Results: Mean percent volume reduction was 83% (±2.7) at 3 weeks and 92.9% (±4.7) at 4 weeks. The tunneled abdominal wound decreased in depth from 7.5 cm to 1.2 cm in 3 weeks. Complete closure was achieved at 11 weeks for the abdominal and groin wounds (patient 1) and at 16 weeks for the thigh wound (patient 3). The scapular wound volume of patient 2 had decreased by 91.8% at week 4 but was not fully restored until week 21. Mean time to closure was 16.1 (±4.7) weeks.

Conclusions: AHSC was effective in covering exposed bone, improving wound bed vascularity, filling in significant wound depth, and achieving complete wound closure with one application in patients with intractable late-effect radiation wounds.

背景:后期效应辐射引起的伤口是一种特别难以管理和治疗的伤口。纤维化、细胞活性受损、缺血和伤口慢性都会损害愈合,当缺损较大或骨等无血管结构暴露时,这种情况变得更加明显。这类伤口的有效治疗选择有限。彻底切除辐照组织,然后关闭远端带蒂或自由皮瓣是最成功的;然而,这通常需要多阶段手术和长时间住院治疗,并伴有明显的供体部位发病率。当伤口很大或在困难的位置,当手术不合适,或者当具有适当经验/技能的外科医生进行此类手术的机会有限时,情况会更加复杂。方法:本病例系列描述了由患者健康皮肤的小全层样本制成的自体异质皮肤结构(AHSC)的使用。对3例顽固性晚期放射伤患者进行了AHSC治疗。病例1描述了一个腹部伤口,有7.5厘米的隧道到耻骨联合,已经治疗了已知的骨髓炎,以及一个较浅的全层腹股沟伤口。病例2描述了一个右肩胛骨暴露的伤口,皮瓣关闭失败。病例3描述了一位接受过广泛放射治疗的肉瘤患者的右大腿伤口。这最终导致膝盖以上截肢,无法愈合,切除的股骨远端完全暴露。所有伤口都存在了10个月以上。结果:3周时平均体积缩小率为83%(±2.7),4周时为92.9%(±4.7)。3周后,腹部隧道伤口深度由7.5 cm减小至1.2 cm。腹部和腹股沟伤口(患者1)在11周时完全闭合,大腿伤口(患者3)在16周时完全闭合。患者2的肩胛骨伤口体积在第4周时下降了91.8%,但直到第21周才完全恢复。平均闭合时间为16.1(±4.7)周。结论:AHSC对顽固性迟发性放射伤患者一次应用可有效覆盖外露骨,改善创面血管状况,显著填充创面深度,实现创面完全闭合。
{"title":"Use of an Autologous Heterogenous Skin Construct in the Treatment of Intractable Late-Effect Radiation Wounds: Case Series.","authors":"Diana Burgueno-Vega,&nbsp;Dilip Shahani,&nbsp;Walter Conlan,&nbsp;Melodie Blakely","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Late-effect radiation-induced wounds represent a particularly difficult category of wounds to manage and treat. Fibrosis, impaired cellular activity, ischemia, and wound chronicity all work to impair healing, and this becomes more pronounced when defects are large or when avascular structures such as bone are exposed. Effective treatment options for this type of wound are limited. Thorough excision of irradiated tissue followed by distal pedicled or free flap closure is the most successful; however, this often requires multiple-stage surgeries and prolonged hospitalization and is associated with significant donor site morbidity. This is complicated further when wounds are large or in difficult locations, when surgery is not appropriate, or when there is limited access to surgeons with the appropriate experience/skill to perform such procedures.</p><p><strong>Methods: </strong>This case series describes the use of an autologous heterogenous skin construct (AHSC) made from a small full-thickness sample of the patient's healthy skin. Three patients with intractable late-effect radiation wounds were treated with AHSC. Case 1 describes an abdominal wound with tunneling of 7.5 cm to the pubic symphysis, which had been treated for known osteomyelitis, and a shallower full-thickness groin wound. Case 2 describes a right scapular wound with exposed bone, which had failed flap closure. Case 3 describes a right thigh wound in a patient who had been treated for sarcoma with extensive radiation therapy. This eventually resulted in an above-the-knee amputation, which failed to heal, and full exposure of the distal end of the resected femur. All wounds had been present for greater than 10 months.</p><p><strong>Results: </strong>Mean percent volume reduction was 83% (±2.7) at 3 weeks and 92.9% (±4.7) at 4 weeks. The tunneled abdominal wound decreased in depth from 7.5 cm to 1.2 cm in 3 weeks. Complete closure was achieved at 11 weeks for the abdominal and groin wounds (patient 1) and at 16 weeks for the thigh wound (patient 3). The scapular wound volume of patient 2 had decreased by 91.8% at week 4 but was not fully restored until week 21. Mean time to closure was 16.1 (±4.7) weeks.</p><p><strong>Conclusions: </strong>AHSC was effective in covering exposed bone, improving wound bed vascularity, filling in significant wound depth, and achieving complete wound closure with one application in patients with intractable late-effect radiation wounds.</p>","PeriodicalId":11687,"journal":{"name":"Eplasty","volume":"23 ","pages":"e34"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350875/pdf/eplasty-23-e34.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10195259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of Stage 4 Pressure Injuries With Autologous Heterogenous Skin Construct: A Single-Center Retrospective Study. 自体异质皮肤结构治疗4期压伤:一项单中心回顾性研究。
Pub Date : 2023-01-01
Diana Burgueño-Vega, Dilip Shahani, Ryan Mathis, Melodie Blakely

Background: Pressure injuries (PIs) are a challenging problem in health care affecting 2.5 million people per year in the US, with 60,000 deaths directly attributed to PIs annually. Surgical closure is the treatment of choice for stage 3 and 4 PIs, but with complication rates of 59% to 73%, less invasive and more effective treatments are needed. Autologous heterogeneous skin construct (AHSC) is a novel autograft made from a small full-thickness harvest of healthy skin. This single-center retrospective cohort study sought to determine the effectiveness of AHSC in the treatment of recalcitrant stage 4 pressure injuries.

Methods: All data were collected retrospectively. The primary efficacy outcome was complete wound closure. Secondary efficacy outcomes included percent area reduction, percent volume reduction, and coverage of exposed structures.

Results: Seventeen patients with 22 wounds were treated with AHSC. Complete closure was achieved in 50% of patients in a mean time of 146 (SD ± 93) days, and the percent area and volume reductions were 69% and 81%, respectively. A 95% volume reduction was achieved in 68.2% of patients at a mean time of 106 (SD ± 83) days, and critical structures were fully covered in 95% of patients in a mean time of 33 (SD ± 19) days. After AHSC treatment, there was a mean decrease of 1.65 hospital admissions (P = .001), 20.92 hospital days (P < .001), and 2.36 operative procedures per year (P < 0.001).

Conclusions: AHSC demonstrated the ability to cover exposed structures, restore wound volume, and achieve durable wound closure in chronic refractory stage 4 PIs with better closure and recurrence rates than current surgical and nonsurgical treatments. AHSC represents a minimally invasive alternative to reconstructive flap surgery that preserves future reconstructive options while minimizing donor-site morbidity and promoting improved patient health.

背景:压力性损伤(PIs)是医疗保健中的一个具有挑战性的问题,每年在美国影响250万人,每年有6万人直接死于PIs。手术关闭是3期和4期pi的治疗选择,但并发症发生率为59%至73%,需要更少侵入性和更有效的治疗。自体异质皮肤结构(AHSC)是一种由少量全层健康皮肤制成的新型自体移植物。这项单中心回顾性队列研究旨在确定AHSC治疗顽固性4期压力损伤的有效性。方法:回顾性收集所有资料。主要疗效指标为伤口完全愈合。次要疗效指标包括面积缩小百分比、体积缩小百分比和暴露结构的覆盖率。结果:17例22处创面均采用AHSC治疗。50%的患者在146 (SD±93)天的平均时间内完全闭合,面积和体积缩小的百分比分别为69%和81%。68.2%的患者在平均106 (SD±83)天内实现了95%的体积缩小,95%的患者在平均33 (SD±19)天内完全覆盖了关键结构。AHSC治疗后,平均每年住院人数减少1.65人(P = 0.001),住院天数减少20.92天(P < 0.001),手术次数减少2.36次(P < 0.001)。结论:AHSC能够覆盖暴露的结构,恢复伤口体积,并在慢性难治性4期pi中实现持久的伤口愈合,比目前的手术和非手术治疗具有更好的愈合和复发率。AHSC代表了重建皮瓣手术的一种微创选择,保留了未来的重建选择,同时最大限度地减少了供体部位的发病率,促进了患者健康的改善。
{"title":"Treatment of Stage 4 Pressure Injuries With Autologous Heterogenous Skin Construct: A Single-Center Retrospective Study.","authors":"Diana Burgueño-Vega,&nbsp;Dilip Shahani,&nbsp;Ryan Mathis,&nbsp;Melodie Blakely","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Pressure injuries (PIs) are a challenging problem in health care affecting 2.5 million people per year in the US, with 60,000 deaths directly attributed to PIs annually. Surgical closure is the treatment of choice for stage 3 and 4 PIs, but with complication rates of 59% to 73%, less invasive and more effective treatments are needed. Autologous heterogeneous skin construct (AHSC) is a novel autograft made from a small full-thickness harvest of healthy skin. This single-center retrospective cohort study sought to determine the effectiveness of AHSC in the treatment of recalcitrant stage 4 pressure injuries.</p><p><strong>Methods: </strong>All data were collected retrospectively. The primary efficacy outcome was complete wound closure. Secondary efficacy outcomes included percent area reduction, percent volume reduction, and coverage of exposed structures.</p><p><strong>Results: </strong>Seventeen patients with 22 wounds were treated with AHSC. Complete closure was achieved in 50% of patients in a mean time of 146 (SD ± 93) days, and the percent area and volume reductions were 69% and 81%, respectively. A 95% volume reduction was achieved in 68.2% of patients at a mean time of 106 (SD ± 83) days, and critical structures were fully covered in 95% of patients in a mean time of 33 (SD ± 19) days. After AHSC treatment, there was a mean decrease of 1.65 hospital admissions (<i>P</i> = .001), 20.92 hospital days (<i>P</i> < .001), and 2.36 operative procedures per year (<i>P</i> < 0.001).</p><p><strong>Conclusions: </strong>AHSC demonstrated the ability to cover exposed structures, restore wound volume, and achieve durable wound closure in chronic refractory stage 4 PIs with better closure and recurrence rates than current surgical and nonsurgical treatments. AHSC represents a minimally invasive alternative to reconstructive flap surgery that preserves future reconstructive options while minimizing donor-site morbidity and promoting improved patient health.</p>","PeriodicalId":11687,"journal":{"name":"Eplasty","volume":"23 ","pages":"e26"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205861/pdf/eplasty-23-e26.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9519486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Skin Anatomy. 皮肤解剖学。
Pub Date : 2023-01-01
Stephen M Milner
{"title":"Skin Anatomy.","authors":"Stephen M Milner","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11687,"journal":{"name":"Eplasty","volume":"23 ","pages":"QA8"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373447/pdf/eplasty-23-QA8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10266861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of Sciatic Nerve Injury Repairs: A Systematic Review. 坐骨神经损伤修复的结果:系统回顾。
Pub Date : 2023-01-01
Ahmed Turkman, Vyshnavi Thanaraaj, Payam Soleimani-Nouri, Elissa Harb, Mehul Thakkar

Background: The objective of this study was to investigate the surgical repair techniques and the outcomes of sciatic nerve injuries in traumatic wounds.

Methods: A literature search was conducted using the following keywords:sciatic, nerve, repair, technique, conduit, graft, reconstruction, outcome, rehabilitation, recovery, function, surgery, and NOT anesthesia.

Results: In total, 715 studies were retrieved. After abstract review, 13 articles fit the criteria. A total of 2627 repairs were carried out, including nerve grafts (n = 953), suture (n = 482), and neurolysis (n = 1192). Six studies reported good motor outcome, and good sensory outcome was reported across 2 studies. The thigh region accounted for 81.5% of lesions. Sciatic, peroneal, and tibial nerves were all equally affected. Gunshot wounds were the most common mechanism of injury (22.6%).

Conclusions: The cumulative evidence demonstrates sciatic nerve injury repair has poor motor and sensory outcomes. This study shows there is a lack of standardized outcome measures, making comparisons very difficult. Graft lengths of <4 cm within the intermediate region yielded more successful outcomes. Further higher quality studies of nerve transfers in the lower limbs are needed to determine the optimal repair to restore sciatic nerve function.

背景:本研究的目的是探讨创伤性创伤后坐骨神经损伤的外科修复技术和治疗效果。方法:使用以下关键词进行文献检索:坐骨、神经、修复、技术、导管、移植物、重建、结局、康复、恢复、功能、手术、非麻醉。结果:共检索到715项研究。摘要综述后,有13篇文章符合标准。共进行了2627例修复,包括神经移植(n = 953)、缝合(n = 482)和神经松解(n = 1192)。6项研究报告了良好的运动结果,2项研究报告了良好的感觉结果。大腿部位病变占81.5%。坐骨神经、腓骨神经和胫神经均受影响。枪伤是最常见的损伤机制(22.6%)。结论:累积证据表明,坐骨神经损伤修复的运动和感觉预后较差。这项研究表明,缺乏标准化的结果衡量标准,使得比较非常困难。接枝长度
{"title":"Outcomes of Sciatic Nerve Injury Repairs: A Systematic Review.","authors":"Ahmed Turkman,&nbsp;Vyshnavi Thanaraaj,&nbsp;Payam Soleimani-Nouri,&nbsp;Elissa Harb,&nbsp;Mehul Thakkar","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The objective of this study was to investigate the surgical repair techniques and the outcomes of sciatic nerve injuries in traumatic wounds.</p><p><strong>Methods: </strong>A literature search was conducted using the following keywords:<i>sciatic, nerve, repair, technique, conduit, graft, reconstruction, outcome, rehabilitation, recovery, function, surgery,</i> and <i>NOT anesthesia.</i></p><p><strong>Results: </strong>In total, 715 studies were retrieved. After abstract review, 13 articles fit the criteria. A total of 2627 repairs were carried out, including nerve grafts (n = 953), suture (n = 482), and neurolysis (n = 1192). Six studies reported good motor outcome, and good sensory outcome was reported across 2 studies. The thigh region accounted for 81.5% of lesions. Sciatic, peroneal, and tibial nerves were all equally affected. Gunshot wounds were the most common mechanism of injury (22.6%).</p><p><strong>Conclusions: </strong>The cumulative evidence demonstrates sciatic nerve injury repair has poor motor and sensory outcomes. This study shows there is a lack of standardized outcome measures, making comparisons very difficult. Graft lengths of <4 cm within the intermediate region yielded more successful outcomes. Further higher quality studies of nerve transfers in the lower limbs are needed to determine the optimal repair to restore sciatic nerve function.</p>","PeriodicalId":11687,"journal":{"name":"Eplasty","volume":"23 ","pages":"e42"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472424/pdf/eplasty-23-e42.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10150952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Smoking as a Risk Factor for Forehead Flap Wound Outcomes: An Analysis of 1030 Patients. 吸烟是前额皮瓣创面预后的危险因素:对1030例患者的分析
Pub Date : 2022-11-11 eCollection Date: 2022-01-01
Salomon Puyana, Carolina Puyana, H Harvak Hajebian, David A Jansen, Abigail E Chaffin

Background: The forehead flap is a local transposition flap based on a pedicled vessel commonly used to reconstruct facial defects. Often patients requiring reconstructions are smokers, yet the effects of smoking on forehead flaps are not well defined. Our study is aimed to examine smoking as a preoperative risk factor for complications following forehead flaps.

Methods: This retrospective cohort study used data collected from the American College of Surgeons National Surgical Quality Improvement Program from 2005 to 2019. Multivariate logistic regression models were fitted to evaluate the association between smoking and development of wound complications.

Results: A total of 1030 forehead flaps cases were analyzed and separated into 2 cohorts based on current smoking status: 789 (76.6%) nonsmokers versus 241 (23.4%) smokers. No significant differences in rates of wound complications were found for nonsmokers versus smokers (2.7% vs 4.1%; P = .0807), including when adjusted for comorbidities in a multivariate logistic regression model (adjusted odds ratio, 1.297 [95% confidence interval, 0.55-2.9]; P = .5174).

Conclusions: Smoking has been demonstrated to be a risk factor for plastic surgery procedures. However, in our review of 1030 forehead flaps, smokers did not have worse outcomes compared with nonsmokers. Although it is still advised to recommend smoking cessation given multiple health benefits, smoking status should not preclude candidacy for facial reconstruction with a forehead flap based on complication risk.

背景:前额皮瓣是一种基于带蒂血管的局部转位皮瓣,常用于面部缺损的重建。通常需要重建的患者是吸烟者,然而吸烟对前额皮瓣的影响还没有很好的定义。我们的研究目的是检查吸烟作为前额皮瓣术后并发症的术前危险因素。方法:本回顾性队列研究使用了2005年至2019年美国外科医师学会国家手术质量改进计划的数据。采用多变量logistic回归模型评估吸烟与伤口并发症发生的关系。结果:共分析1030例前额皮瓣病例,并根据吸烟状况分为2组:789例(76.6%)非吸烟者和241例(23.4%)吸烟者。不吸烟者与吸烟者的伤口并发症发生率无显著差异(2.7% vs 4.1%;P = 0.0807),包括在多因素logistic回归模型中校正合并症(校正优势比为1.297[95%可信区间,0.55-2.9];P = .5174)。结论:吸烟已被证明是整形手术的一个危险因素。然而,在我们对1030例前额皮瓣的回顾中,吸烟者的结果并不比不吸烟者差。尽管考虑到多种健康益处,仍建议戒烟,但吸烟状况不应排除基于并发症风险的前额皮瓣面部重建的候选资格。
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Eplasty
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