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Vascular Mapping for Abdominal-Based Breast Reconstruction: A Comprehensive Review of Current and Upcoming Imaging Modalities. 基于腹部乳房重建的血管测绘:当前和即将到来的成像方式的综合回顾。
Pub Date : 2023-01-01
Taylor J Ibelli, Sumanth Chennareddy, Max Mandelbaum, Peter W Henderson

Background: Preoperative vascular imaging is a very common element of surgical planning for abdominal-based breast reconstruction (ABBR). Surgeons must tailor which flap is best suited for each respective patient based on the patient's health and vascular anatomy. The goal of this review is to give surgeons practical tools for choosing which imaging technology best suits their patient's needs for successful breast reconstruction.

Methods: A review of literature was undertaken on Google scholar to assess preoperative imaging modalities used for ABBR. Search terms included breast reconstruction, deep inferior epigastric perforator (DIEP) flap, and abdominal imaging. Articles were included based on relevance and significance to ABBR. Advantages and disadvantages of each imaging modality were then classified according to clinically relevant utility.

Results: Overall, imaging technologies that produce 3-dimensional images were found to have greater resolution for identifying perforators and the pedicle network than 2- dimensional images.

Conclusions: This paper addresses the strengths and weaknesses of the currently used imaging modalities described and also discusses new technologies that may be helpful in the future for planning of ABBR.

背景:术前血管成像是腹部乳房重建(ABBR)手术计划中非常常见的元素。外科医生必须根据病人的健康状况和血管解剖结构为每个病人量身定制最适合的皮瓣。这篇综述的目的是给外科医生提供实用的工具,帮助他们选择最适合患者需要的成像技术,以获得成功的乳房重建。方法:在Google scholar上查阅文献,评估ABBR术前影像学方式。检索词包括乳房重建、上腹部深下穿支(DIEP)皮瓣和腹部影像学。根据ABBR的相关性和重要性纳入文章,然后根据临床相关效用对每种成像方式的优缺点进行分类。结果:总的来说,与二维图像相比,三维成像技术在识别穿支和椎弓根网络方面具有更高的分辨率。结论:本文阐述了目前使用的成像模式的优缺点,并讨论了可能有助于未来ABBR规划的新技术。
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引用次数: 0
Soft Tissue Reconstruction With Ovine Forestomach Matrix After Wide Excision of Plantar Fibromatosis. 羊足底纤维瘤病广泛切除后用前胃基质重建软组织。
Pub Date : 2023-01-01
Abby B Duplechain, Brandon A Bosque, Caleb W Fligor, Abigail E Chaffin

Background. Plantar fibromatosis, or Ledderhose disease, presents as plantar fascia nodules caused by hyperactive proliferating fibroblasts. These benign tumorous growths can persist causing pain as well as reduced mobility and quality of life. Plantar fibromatosis may not respond to conservative nonsurgical treatment resulting in surgical intervention, including wide excision of the affected tissue and subsequent reconstruction. Reconstruction of the full-thickness plantar defect is challenging given the location, and recurrence rates are relatively high. Here we present a staged reconstruction of plantar fibromatosis following wide excision using a biologic graft to regenerate the neodermis and subsequent skin grafting. This reconstructive approach provided an alternative to free flap transfer, with excellent functional outcomes.

背景。足底纤维瘤病,或皮靴病,表现为足底筋膜结节,由过度活跃的增殖成纤维细胞引起。这些良性肿瘤的生长可以持续引起疼痛,降低活动能力和生活质量。足底纤维瘤病可能对保守的非手术治疗无效,导致手术干预,包括广泛切除受影响的组织并随后重建。重建全层足底缺损是具有挑战性的位置,复发率相对较高。在这里,我们提出一个分阶段重建足底纤维瘤病后广泛切除使用生物移植物再生新生真皮和随后的皮肤移植。这种重建方法提供了自由皮瓣转移的另一种选择,具有良好的功能效果。
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引用次数: 0
Redesigning Sentinel Lymph Node Biopsy Guidelines in Melanoma Cases. 重新设计黑色素瘤病例前哨淋巴结活检指南。
Pub Date : 2023-01-01
Samuel A Stetkevich, Richard Simman

Background: Accurately staging and prognosticating melanoma classically depends on a sentinel lymph node biopsy (SLNB). The mainstay predictors of SLNB positivity according to the American Joint Committee on Cancer (AJCC) are Breslow depth and ulceration. Nevertheless, even with these predictors, negative SLNBs, even in deep melanomas, are a common occurrence and may result in unnecessary invasive procedures for patients. This suggests that the parameters for determining SLNB candidates are a potential area for improvement in surgical dermatology (surgical oncology and plastic surgery).

Methods: The authors conducted a systemic review to assess current AJCC guidelines on when a SLNB in melanoma is indicated. We also investigated how age, mitotic rate, lymphovascular invasion, satellitosis, melanoma subtype, anatomical location, and an immunocompromised state affected positivity rates in sentinel lymph node biopsies in melanoma.

Results: These variables significantly impacted SLNB positivity rates and serve as evidence to support the proposal of redesigning SLNB guidelines in melanoma.

Conclusions: Integrating the current AJCC guidelines with the newly examined variables will create patient-specific recommendations centered on the aim of reducing the number of invasive procedures while increasing SLNB positivity rates and prognostication.

背景:黑色素瘤的准确分期和预后通常依赖于前哨淋巴结活检(SLNB)。根据美国癌症联合委员会(AJCC)的研究,SLNB阳性的主要预测指标是血管深度和溃疡。然而,即使有这些预测因素,slnb阴性,即使在深部黑色素瘤中,也是常见的,并可能导致患者进行不必要的侵入性手术。这表明用于确定SLNB候选者的参数是外科皮肤病学(外科肿瘤学和整形外科)改进的潜在领域。方法:作者进行了一项系统综述,以评估目前AJCC关于黑色素瘤何时需要SLNB的指南。我们还研究了年龄、有丝分裂率、淋巴血管侵袭、卫星病、黑色素瘤亚型、解剖位置和免疫功能低下状态如何影响黑色素瘤前哨淋巴结活检的阳性率。结果:这些变量显著影响SLNB阳性率,并作为证据支持重新设计黑色素瘤SLNB指南的建议。结论:将当前的AJCC指南与新检查的变量相结合,将产生针对患者的具体建议,其目标是减少侵入性手术的数量,同时提高SLNB的阳性率和预后。
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引用次数: 0
Radiation-Induced Morphea of the Breast Treated With Wide Local Excision and Abdominal Free Flap Breast Reconstruction. 大面积局部切除及腹部游离皮瓣乳房重建治疗放射性乳房坏死。
Pub Date : 2023-01-01
Ashley Titan, Anita T Mohan, Minami Tokuyama, Jacob Mirbegian, Gregory R Bean, Gordon K Lee

Radiation-induced morphea (RIM) associated with breast cancer treatment is a rare and underdiagnosed skin complication of radiotherapy that can lead to severe and painful contractures, resulting in disfigurement, failure of reconstruction, and poor quality of life in patients. The condition may present on a spectrum of local or more generalized forms involving skin over the breast and anterior chest wall. This diagnosis must be differentiated from post-radiation fibrosis, infection, cancer recurrence, inflammatory breast cancer, and other inflammatory conditions as the clinical course and treatment approaches differ. Various noninvasive and topical agents have been used; however, many cases are refractory to treatment. Surgery has been less commonly described in the management of generalized RIM. This report describes a case of RIM in a patient with breast cancer who experienced simultaneous resolution of symptoms as well as successful breast reconstruction using autologous free-tissue transfer.

与乳腺癌治疗相关的放射诱发性皮肤坏死(RIM)是一种罕见且未被诊断的放射治疗皮肤并发症,可导致严重和痛苦的挛缩,导致毁容、重建失败和患者生活质量差。这种情况可能表现为局部或更广泛的形式,包括乳房和胸壁上的皮肤。由于临床病程和治疗方法不同,必须将此诊断与放疗后纤维化、感染、癌症复发、炎性乳腺癌和其他炎性疾病区分开来。已经使用了各种非侵入性和局部药物;然而,许多病例难以治疗。手术治疗广泛性RIM的方法较少。本报告描述了一例RIM患者的乳腺癌谁经历了同时解决的症状,以及成功的乳房重建使用自体游离组织移植。
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引用次数: 0
Nasal Soft Tissue Triangle Large Composite Graft Take With Postoperative Hyperbaric Oxygen Therapy: A Case Report. 鼻软组织三角形大复合移植物术后高压氧治疗1例。
Pub Date : 2023-01-01
Carly A Askinas, Igor Burko, Jadyn Heffern, Salomon Puyana, David A Jansen

Background: Auricular composite grafts hold great potential for reconstructing the nasal soft tissue triangle with desired aesthetic results because there is ample tissue available for sufficient nasal ala projection and the natural curvature of the helical rim matches that of the alar rim. The use of auricular composite grafts also results in positive functional outcomes because of the cartilaginous airway support provided to widen the external nasal valve. Composite graft survival is highly dependent on graft size, as larger sized grafts have a higher metabolic demand.To improve graft viability and reliability, hyperbaric oxygen therapy can be employed to accommodate the increased metabolic demand seen with larger composite grafts.

Conclusions: This report presents the survival of a large skin and cartilage composite graft for nasal soft tissue triangle reconstruction in conjunction with hyperbaric oxygen therapy to improve graft viability.

背景:耳廓复合移植物在重建鼻软组织三角形方面具有巨大的潜力,具有理想的美学效果,因为有足够的组织可用于足够的鼻翼投影,并且螺旋边缘的自然曲率与鼻翼边缘相匹配。耳廓复合移植物的使用也会产生积极的功能结果,因为提供了软骨气道支持来扩大鼻外瓣膜。复合移植物的存活高度依赖于移植物的大小,因为较大的移植物具有较高的代谢需求。为了提高移植物的生存能力和可靠性,高压氧治疗可以用来适应更大的复合移植物增加的代谢需求。结论:本报告介绍了用于鼻软组织三角重建的大皮肤和软骨复合移植物的存活率,并结合高压氧治疗以提高移植物的存活率。
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引用次数: 0
Breast Implants Save Lives: Gunshot Wound to a Silicone Gel Implant. 乳房植入物拯救生命:枪伤到硅胶植入物。
Pub Date : 2023-01-01
Brooke E Barrow, Milind D Kachare, Alyssa M Simpson, Natalie J West, Samuel L Corey, Bradon J Wilhelmi

What is the incidence of gunshot injuries involving breast implants?What are the considerations for managing a patient with a gunshot wound to a breast implant?Can a breast implant alter the trajectory of a bullet to the chest?What are the considerations for reconstructing a breast after a gunshot wound?

涉及隆胸的枪伤发生率是多少?对乳房植入物中枪伤的患者进行治疗需要考虑哪些因素?隆胸手术能改变子弹射入胸部的轨迹吗?枪伤后乳房再造需要考虑哪些因素?
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引用次数: 0
Epidermoid Cyst of Orbit Requiring Cranialization of Frontal Sinus. 眼眶表皮样囊肿需要额窦开颅术。
Pub Date : 2023-01-01
Tadaaki Morotomi, Hitoshi Nishiwaki, Tomomi Iuchi, Yasuhiro Sanada, Hitomi Nakao, Mitsugu Fujita, Koji Niwa

How often do intracranial epidermoid cysts occur?Is a coronary incision necessary?What are the steps of the procedure, difficulties encountered, and process for circumventing those difficulties?What is the follow-up protocol and outcome?

颅内表皮样囊肿多久发生一次?有必要做冠状动脉切口吗?程序的步骤、遇到的困难和规避这些困难的过程是什么?随访方案和结果是什么?
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引用次数: 0
The 5 D's to Dunk the Dog: A Retrospective Clinical Review to Prevent Dog-Ear Contour Abnormalities in Vertical Breast Reductions and Breast Lifts. 5个D来浸泡狗:预防垂直缩胸和隆胸中狗耳轮廓异常的回顾性临床回顾。
Pub Date : 2023-01-01
Swapnil D Kachare, Milind D Kachare, Bradley J Vivace, Brooke E Barrow, Michael Ablavsky, Sara Abell, Joshua H Choo, Bradon J Wilhelmi

Background: In 2020, reduction mammoplasties and mastopexies comprised 34.2% of all breast surgeries performed by plastic surgeons. Various approaches for the skin incision of these procedures have been described. The vertical pattern has become an increasingly popular option due to its lower scar burden. However, it is prone to dog-ear formation along the caudal aspect of the incision. Herein, we describe 5 technical steps to eliminate the dog-ear in patients undergoing vertical mammoplasties.

Methods: A retrospective chart review was performed on all patients who underwent vertical breast reduction and mastopexy between the years 2008 and 2020 performed by the senior author. The 5 steps employed in eliminating the dog-ear are delineated and depicted pictorially.

Results: A total of 58 patients and 89 breasts were operated upon. A majority of 66.6% were Caucasian, 33.3% were African American, and 1 patient was of Hispanic descent. The mean age was 53.2 years (19-73 years), and average BMI was 31.5 kg/m2 (21.3-42.7 kg/m2). The average resection weights for reduction and mastopexy patients were 479 grams (100-1500 grams) and 58.1 grams (18-100 grams), respectively. Mean follow-up was 10.5 months (1-35 months). Only one patient developed a dog-ear (1.7%) in bilateral breasts (2.2%); however, the patient did not request a revision. Our revision rate over 13 years remained at 0%.

Conclusions: Utilizing these 5 technical steps reduces the risk of dog-ear deformity and thereby diminishes the overall need for revisional surgery in patients undergoing short scar vertical mammoplasties.

背景:2020年,乳房缩小和乳房切除术占整形外科医生进行的所有乳房手术的34.2%。各种方法的皮肤切口这些程序已被描述。由于其较低的疤痕负担,垂直模式已成为越来越受欢迎的选择。然而,它很容易沿切口的尾端形成狗耳。在这里,我们描述了5个技术步骤,以消除狗耳患者接受垂直乳房整形手术。方法:回顾性分析资深作者2008年至2020年间所有行垂直缩乳和乳房固定术的患者。在消除狗耳所采用的5个步骤被描绘和图解。结果:共手术58例,89个乳房。白人占66.6%,非裔美国人占33.3%,西班牙裔1例。平均年龄53.2岁(19 ~ 73岁),平均BMI为31.5 kg/m2 (21.3 ~ 42.7 kg/m2)。乳房复位和乳房固定术患者的平均切除重量分别为479克(100-1500克)和58.1克(18-100克)。平均随访10.5个月(1 ~ 35个月)。只有1例患者双侧乳房(2.2%)出现狗耳(1.7%);然而,患者并未要求复查。我们13年来的修正率保持在0%。结论:利用这5个技术步骤可以降低狗耳畸形的风险,从而减少了接受短疤痕垂直乳房成形术患者翻修手术的总体需求。
{"title":"The 5 D's to Dunk the Dog: A Retrospective Clinical Review to Prevent Dog-Ear Contour Abnormalities in Vertical Breast Reductions and Breast Lifts.","authors":"Swapnil D Kachare,&nbsp;Milind D Kachare,&nbsp;Bradley J Vivace,&nbsp;Brooke E Barrow,&nbsp;Michael Ablavsky,&nbsp;Sara Abell,&nbsp;Joshua H Choo,&nbsp;Bradon J Wilhelmi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>In 2020, reduction mammoplasties and mastopexies comprised 34.2% of all breast surgeries performed by plastic surgeons. Various approaches for the skin incision of these procedures have been described. The vertical pattern has become an increasingly popular option due to its lower scar burden. However, it is prone to dog-ear formation along the caudal aspect of the incision. Herein, we describe 5 technical steps to eliminate the dog-ear in patients undergoing vertical mammoplasties.</p><p><strong>Methods: </strong>A retrospective chart review was performed on all patients who underwent vertical breast reduction and mastopexy between the years 2008 and 2020 performed by the senior author. The 5 steps employed in eliminating the dog-ear are delineated and depicted pictorially.</p><p><strong>Results: </strong>A total of 58 patients and 89 breasts were operated upon. A majority of 66.6% were Caucasian, 33.3% were African American, and 1 patient was of Hispanic descent. The mean age was 53.2 years (19-73 years), and average BMI was 31.5 kg/m<sup>2</sup> (21.3-42.7 kg/m<sup>2</sup>). The average resection weights for reduction and mastopexy patients were 479 grams (100-1500 grams) and 58.1 grams (18-100 grams), respectively. Mean follow-up was 10.5 months (1-35 months). Only one patient developed a dog-ear (1.7%) in bilateral breasts (2.2%); however, the patient did not request a revision. Our revision rate over 13 years remained at 0%.</p><p><strong>Conclusions: </strong>Utilizing these 5 technical steps reduces the risk of dog-ear deformity and thereby diminishes the overall need for revisional surgery in patients undergoing short scar vertical mammoplasties.</p>","PeriodicalId":11687,"journal":{"name":"Eplasty","volume":"23 ","pages":"e13"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008304/pdf/eplasty-23-e13.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9121491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Are Large Intraoperative Fill Volumes Associated With Increased Complications After Tissue Expander Placement? 术中填充量大是否与组织扩张器置入后并发症增加有关?
Pub Date : 2023-01-01
Nikita Kadakia, Austin R Swisher, Priya G Lewis, Mark J Landau, Jeremy Kubiak, Waseem Mohiuddin, Hahns Y Kim

Background: With the increased adoption of skin-sparing mastectomies, immediate 2-stage breast reconstruction is a common option for breast cancer patients. During the first stage of the procedure with tissue expander placement, higher intraoperative percent fill has been identified as a risk factor for complications. However, the postoperative outcomes of higher intraoperative fill volumes are not well established. The authors sought to evaluate if a higher initial intraoperative tissue expander fill volume is associated with higher complication rates in patients undergoing immediate breast reconstruction with tissue expander placement.

Methods: A retrospective review of patients who underwent immediate breast reconstruction with a tissue expander placement from 2016 to 2018 was conducted. Patient demographics and perioperative data were recorded. Large intraoperative fill was defined as saline fill volume greater than 350 mL. The primary outcome evaluated was skin and nipple necrosis. Secondary outcomes were major infections, minor infections, seroma, and hematoma.

Results: A total of 147 breasts in 86 patients were included. Mean intraoperative fill volume was 246.4 ± 106.6 mL. Thirty-five tissue expanders were filled with greater than 350 mL of saline intraoperatively. Patients with large intraoperative fill volume were older (mean age, 52.6 vs 47.9 years; P = .04), had a higher mean body mass index (BMI; 33.2 vs 25.9 kg/m2; P < .0001), and had larger preoperative breast anthropometrics (P < .0001). During a mean follow-up period of 20.1 months (range, 3-55 months), 9 breasts were noted to have skin/nipple necrosis. After multivariate analysis, large tissue expander fill volume was not a significant predictor of skin or nipple necrosis (P = .62). Hypertension and anticoagulant use were associated with increased skin and nipple necrosis (P = .04 and P = .03, respectively). Large fill volume was not associated with statistically significant increases in rates of other complications like major infections, minor infections, seroma, or hematoma.

Conclusions: Larger fill volumes are often required and benefit patients with higher BMI or bra sizes. This also reduces the number of postoperative fills required. In this patient population, larger intraoperative tissue expander saline fill volume (greater than 350 mL) was not associated with increased postoperative complications. After careful patient selection and perfusion evaluation, larger fill volumes may be considered a safe option to improve the aesthetic outcomes in patients with high BMI.

背景:随着保留皮肤的乳房切除术的采用越来越多,立即二期乳房重建是乳腺癌患者的常见选择。在放置组织扩张器的手术的第一阶段,较高的术中填充率已被确定为并发症的危险因素。然而,术中填充体积增大的术后结果尚未得到很好的确定。作者试图评估是否较高的初始术中组织扩张器填充量与组织扩张器放置的立即乳房重建患者较高的并发症发生率相关。方法:回顾性分析2016年至2018年行组织扩张器置入术的即刻乳房再造术患者。记录患者人口统计学和围手术期数据。术中填充量大定义为生理盐水填充量大于350 mL。评估的主要结果是皮肤和乳头坏死。次要结局为严重感染、轻微感染、血肿和血肿。结果:共纳入86例患者147个乳房。平均术中填充量为246.4±106.6 mL。35个组织扩张器术中填充大于350ml的生理盐水。术中填充量较大的患者年龄较大(平均年龄52.6岁vs 47.9岁;P = .04),平均体重指数(BMI;33.2 vs 25.9 kg/m2;P < 0.0001),术前乳房人体测量值较大(P < 0.0001)。在平均20.1个月的随访期间(范围3-55个月),9个乳房出现皮肤/乳头坏死。多变量分析后,较大的组织扩张器填充量并不是皮肤或乳头坏死的显著预测因子(P = 0.62)。高血压和抗凝剂的使用与皮肤和乳头坏死增加相关(P = 0.04和P = 0.03)。大填充量与其他并发症如严重感染、轻微感染、血肿或血肿发生率的统计学显著增加无关。结论:通常需要较大的填充量,并且有利于BMI或胸罩尺寸较高的患者。这也减少了术后所需的补牙次数。在该患者群体中,术中较大的组织扩张器生理盐水填充量(大于350ml)与术后并发症的增加无关。在仔细的患者选择和灌注评估后,更大的填充体积可以被认为是一个安全的选择,以改善高BMI患者的美学结果。
{"title":"Are Large Intraoperative Fill Volumes Associated With Increased Complications After Tissue Expander Placement?","authors":"Nikita Kadakia,&nbsp;Austin R Swisher,&nbsp;Priya G Lewis,&nbsp;Mark J Landau,&nbsp;Jeremy Kubiak,&nbsp;Waseem Mohiuddin,&nbsp;Hahns Y Kim","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>With the increased adoption of skin-sparing mastectomies, immediate 2-stage breast reconstruction is a common option for breast cancer patients. During the first stage of the procedure with tissue expander placement, higher intraoperative percent fill has been identified as a risk factor for complications. However, the postoperative outcomes of higher intraoperative fill volumes are not well established. The authors sought to evaluate if a higher initial intraoperative tissue expander fill volume is associated with higher complication rates in patients undergoing immediate breast reconstruction with tissue expander placement.</p><p><strong>Methods: </strong>A retrospective review of patients who underwent immediate breast reconstruction with a tissue expander placement from 2016 to 2018 was conducted. Patient demographics and perioperative data were recorded. Large intraoperative fill was defined as saline fill volume greater than 350 mL. The primary outcome evaluated was skin and nipple necrosis. Secondary outcomes were major infections, minor infections, seroma, and hematoma.</p><p><strong>Results: </strong>A total of 147 breasts in 86 patients were included. Mean intraoperative fill volume was 246.4 ± 106.6 mL. Thirty-five tissue expanders were filled with greater than 350 mL of saline intraoperatively. Patients with large intraoperative fill volume were older (mean age, 52.6 vs 47.9 years; <i>P</i> = .04), had a higher mean body mass index (BMI; 33.2 vs 25.9 kg/m<sup>2</sup>; <i>P</i> < .0001), and had larger preoperative breast anthropometrics (<i>P</i> < .0001). During a mean follow-up period of 20.1 months (range, 3-55 months), 9 breasts were noted to have skin/nipple necrosis. After multivariate analysis, large tissue expander fill volume was not a significant predictor of skin or nipple necrosis (<i>P</i> = .62). Hypertension and anticoagulant use were associated with increased skin and nipple necrosis (<i>P</i> = .04 and <i>P</i> = .03, respectively). Large fill volume was not associated with statistically significant increases in rates of other complications like major infections, minor infections, seroma, or hematoma.</p><p><strong>Conclusions: </strong>Larger fill volumes are often required and benefit patients with higher BMI or bra sizes. This also reduces the number of postoperative fills required. In this patient population, larger intraoperative tissue expander saline fill volume (greater than 350 mL) was not associated with increased postoperative complications. After careful patient selection and perfusion evaluation, larger fill volumes may be considered a safe option to improve the aesthetic outcomes in patients with high BMI.</p>","PeriodicalId":11687,"journal":{"name":"Eplasty","volume":"23 ","pages":"e12"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008373/pdf/eplasty-23-e12.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9121496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of Local Antibiotic Delivery Systems in Tissue Expander and Implant-Based Breast Reconstruction: A Systematic Review of the Literature. 局部抗生素输送系统在组织扩张器和假体乳房重建中的应用:文献系统综述。
Pub Date : 2023-01-01
Nathan Makarewicz, Kelsey Lipman, Thomas Johnstone, Mohammed Shaheen, Jennifer Krupa Shah, Rahim Nazerali

Background: Periprosthetic infections are a debilitating complication of alloplastic breast reconstruction. Local antibiotic delivery for prophylaxis and infection clearance has been used by other surgical specialties but rarely in breast reconstruction. Because local delivery can maintain high antibiotic concentrations with lower toxicity risk, it may be valuable for infection prophylaxis or salvage in breast reconstruction.

Methods: A systematic search of the Embase, PubMed, and Cochrane databases was performed in January 2022. Primary literature studies examining local antibiotic delivery systems for either prophylaxis or salvage of periprosthetic infections were included. Study quality and bias were assessed using the validated MINORS criteria.

Results: Of 355 publications reviewed, 8 met the predetermined inclusion criteria; 5 papers investigated local antibiotic delivery for salvage, and 3 investigated infection prophylaxis. Implantable antibiotic delivery devices included polymethylmethacrylate, calcium sulfate, and collagen sponges impregnated with antibiotics. Non-implantable antibiotic delivery methods used irrigation with antibiotic solution into the breast pocket. All studies indicated that local antibiotic delivery was either comparable or superior to conventional methods in both the salvage and prophylaxis settings.

Conclusions: Despite varied sample sizes and methodologies, all papers endorsed local antibiotic delivery as a safe, effective method of preventing or treating periprosthetic infections in breast reconstruction.

背景:假体周围感染是同种异体乳房重建的一个衰弱并发症。局部抗生素递送预防和感染清除已用于其他外科专科,但很少用于乳房重建。由于局部分娩可保持较高的抗生素浓度,毒性风险较低,可能对预防感染或乳房再造的抢救有价值。方法:于2022年1月对Embase、PubMed和Cochrane数据库进行系统检索。主要文献研究检查局部抗生素输送系统预防或挽救假体周围感染。使用经过验证的未成年人标准评估研究质量和偏倚。结果:在355篇文献中,有8篇符合预定的纳入标准;5篇研究了抢救性局部抗生素的使用,3篇研究了感染预防。植入式抗生素输送装置包括聚甲基丙烯酸甲酯、硫酸钙和胶原蛋白海绵浸渍抗生素。非植入式抗生素给药方法采用抗生素溶液冲洗乳房袋。所有的研究都表明,在抢救和预防方面,局部抗生素的使用与传统方法相当或优于传统方法。结论:尽管样本量和方法各不相同,但所有的论文都赞同局部抗生素给药是一种安全有效的预防或治疗乳房重建假体周围感染的方法。
{"title":"Use of Local Antibiotic Delivery Systems in Tissue Expander and Implant-Based Breast Reconstruction: A Systematic Review of the Literature.","authors":"Nathan Makarewicz,&nbsp;Kelsey Lipman,&nbsp;Thomas Johnstone,&nbsp;Mohammed Shaheen,&nbsp;Jennifer Krupa Shah,&nbsp;Rahim Nazerali","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Periprosthetic infections are a debilitating complication of alloplastic breast reconstruction. Local antibiotic delivery for prophylaxis and infection clearance has been used by other surgical specialties but rarely in breast reconstruction. Because local delivery can maintain high antibiotic concentrations with lower toxicity risk, it may be valuable for infection prophylaxis or salvage in breast reconstruction.</p><p><strong>Methods: </strong>A systematic search of the Embase, PubMed, and Cochrane databases was performed in January 2022. Primary literature studies examining local antibiotic delivery systems for either prophylaxis or salvage of periprosthetic infections were included. Study quality and bias were assessed using the validated MINORS criteria.</p><p><strong>Results: </strong>Of 355 publications reviewed, 8 met the predetermined inclusion criteria; 5 papers investigated local antibiotic delivery for salvage, and 3 investigated infection prophylaxis. Implantable antibiotic delivery devices included polymethylmethacrylate, calcium sulfate, and collagen sponges impregnated with antibiotics. Non-implantable antibiotic delivery methods used irrigation with antibiotic solution into the breast pocket. All studies indicated that local antibiotic delivery was either comparable or superior to conventional methods in both the salvage and prophylaxis settings.</p><p><strong>Conclusions: </strong>Despite varied sample sizes and methodologies, all papers endorsed local antibiotic delivery as a safe, effective method of preventing or treating periprosthetic infections in breast reconstruction.</p>","PeriodicalId":11687,"journal":{"name":"Eplasty","volume":"23 ","pages":"e24"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176462/pdf/eplasty-23-e24.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9829680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Eplasty
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