首页 > 最新文献

Eplasty最新文献

英文 中文
Intramedullary Free Gracilis for Dead-Space Obliteration and Stump Resurfacing in a Transfemoral Amputee With Recurrent Osteomyelitis. 髓内游离股薄肌治疗复发性骨髓炎经股截肢患者的死腔闭塞和残端置换。
Pub Date : 2023-01-01
Peter Laub, John Vandevender, Maelee Yang, Hobie Summers, Darl Vandevender

Background: A 72-year-old man with a history of delayed presentation for severe right lower extremity burns underwent through-knee amputation complicated by periprosthetic distal femur osteomyelitis. Subsequent transfemoral amputation was complicated by Stage IVB Cierny-Mader osteomyelitis despite appropriate medical and surgical treatment.

Methods: Due to the presence of threatened proximal femur intramedullary nail from prior intertrochanteric femur fracture, inability to further shorten femur, and lack of local soft-tissue options, we performed soft tissue reconstruction with free gracilis flap. The free gracilis flap was pulled proximally through the femoral canal to obliterate intramedullary dead space and provide distal femoral stump coverage.

Results: The stump was fully healed upon 6-month follow-up with computerized tomography demonstrating continued presence of gracilis flap within the femoral canal and no evidence of osteomyelitis. At 1-year follow-up, the patient was ambulatory using a prosthetic without recurrence of osteomyelitis.

Conclusions: Previous descriptions of intramedullary free muscle flaps for the treatment of osteomyelitis are limited in number, with its function being limited to dead-space obliteration. This report presents intramedullary free gracilis flap to be a viable option in above-knee amputees for combined dead space obliteration and stump resurfacing in the context of recurrent osteomyelitis.

背景:一名72岁男性,因严重右下肢烧伤延迟就诊,经膝关节截肢并发假体周围股骨远端骨髓炎。尽管经过适当的药物和手术治疗,随后经股骨截肢并发IVB期谢尼-马德氏骨髓炎。方法:由于先前股骨粗隆间骨折存在威胁股骨近端髓内钉,无法进一步缩短股骨,且缺乏局部软组织选择,我们采用游离股薄肌皮瓣进行软组织重建。游离股薄肌瓣通过股骨管近端牵拉,以消除髓内死亡空间,并提供远端股骨残端覆盖。结果:在6个月的随访中,残端完全愈合,计算机断层扫描显示股薄肌皮瓣在股管内持续存在,无骨髓炎的证据。在1年的随访中,患者使用假体行走,没有骨髓炎复发。结论:以往关于髓内游离肌瓣治疗骨髓炎的报道数量有限,其功能仅限于封堵死区。本报告提出髓内游离股薄肌皮瓣是一种可行的选择,在膝上截肢联合死腔闭塞和残肢置换的背景下,复发性骨髓炎。
{"title":"Intramedullary Free Gracilis for Dead-Space Obliteration and Stump Resurfacing in a Transfemoral Amputee With Recurrent Osteomyelitis.","authors":"Peter Laub,&nbsp;John Vandevender,&nbsp;Maelee Yang,&nbsp;Hobie Summers,&nbsp;Darl Vandevender","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>A 72-year-old man with a history of delayed presentation for severe right lower extremity burns underwent through-knee amputation complicated by periprosthetic distal femur osteomyelitis. Subsequent transfemoral amputation was complicated by Stage IVB Cierny-Mader osteomyelitis despite appropriate medical and surgical treatment.</p><p><strong>Methods: </strong>Due to the presence of threatened proximal femur intramedullary nail from prior intertrochanteric femur fracture, inability to further shorten femur, and lack of local soft-tissue options, we performed soft tissue reconstruction with free gracilis flap. The free gracilis flap was pulled proximally through the femoral canal to obliterate intramedullary dead space and provide distal femoral stump coverage.</p><p><strong>Results: </strong>The stump was fully healed upon 6-month follow-up with computerized tomography demonstrating continued presence of gracilis flap within the femoral canal and no evidence of osteomyelitis. At 1-year follow-up, the patient was ambulatory using a prosthetic without recurrence of osteomyelitis.</p><p><strong>Conclusions: </strong>Previous descriptions of intramedullary free muscle flaps for the treatment of osteomyelitis are limited in number, with its function being limited to dead-space obliteration. This report presents intramedullary free gracilis flap to be a viable option in above-knee amputees for combined dead space obliteration and stump resurfacing in the context of recurrent osteomyelitis.</p>","PeriodicalId":11687,"journal":{"name":"Eplasty","volume":"23 ","pages":"e46"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472422/pdf/eplasty-23-e46.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10150949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cleft Palate Fistula: A Review. 腭裂瘘:综述。
Pub Date : 2023-01-01
Mitchell Buller, Diana Jodeh, Fatima Qamar, Joshua M Wright, Jordan N Halsey, S Alex Rottgers

Background: The development of postoperative oronasal fistulae (ONF) is a complication that plagues all cleft surgeons to varying degrees. There is extensive literature discussing the incidence, functional impact, and treatment of ONF. The goal of this article is to provide an extensive review of the literature discussing the incidence, causative factors, functional impact, classification systems, and treatment of ONF.

Methods: A literature review was performed using PubMed using the Medical Subject Heading terms "cleft palate" AND "fistula" OR "palatal fistula" OR "oronasal fistula". After review, a total of 356 articles were deemed relevant for this study.

Results: Information regarding ONF care, prevention, and management in patients with cleft palate was collected from the articles included in this review. Treatment of ONF remains a challenging problem as there is not a consensus in the available literature on the best palatoplasty techniques for their prevention and treatment. A myriad of reconstructive options and adjunctive therapies exist, and their use is guided by the size and location of the fistula.

Conclusions: Fistula treatment should be tailored to the specific needs of the patient, and consideration must be given to not only the ONF itself but also the patient's stage of growth and development. Large-scale, multicenter studies are needed in which ONF are described using standardized nomenclature, and improved outcomes reporting is necessary to better define an algorithm for a truly holistic approach to palate surgery and reduce the incidence of palatal fistula.

背景:术后口鼻瘘(ONF)的发展是不同程度困扰所有唇裂外科医生的并发症。有大量文献讨论ONF的发病率、功能影响和治疗。本文的目的是提供广泛的文献综述,讨论ONF的发病率、病因、功能影响、分类系统和治疗。方法:以医学主题词“腭裂”和“瘘”或“腭瘘”或“口鼻瘘”为检索词,在PubMed上进行文献综述。经审查,共有356篇文章被认为与本研究相关。结果:本综述收集了有关腭裂患者ONF护理、预防和管理的信息。ONF的治疗仍然是一个具有挑战性的问题,因为在现有文献中没有关于预防和治疗ONF的最佳腭成形术的共识。存在无数的重建选择和辅助治疗,它们的使用是由瘘的大小和位置指导。结论:瘘管的治疗应根据患者的具体需求量身定制,不仅要考虑ONF本身,还要考虑患者的生长发育阶段。需要进行大规模、多中心的研究,在这些研究中使用标准化的命名法来描述ONF,并且需要改进结果报告,以便更好地定义一个真正全面的腭裂手术方法的算法,并减少腭瘘的发生率。
{"title":"Cleft Palate Fistula: A Review.","authors":"Mitchell Buller,&nbsp;Diana Jodeh,&nbsp;Fatima Qamar,&nbsp;Joshua M Wright,&nbsp;Jordan N Halsey,&nbsp;S Alex Rottgers","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The development of postoperative oronasal fistulae (ONF) is a complication that plagues all cleft surgeons to varying degrees. There is extensive literature discussing the incidence, functional impact, and treatment of ONF. The goal of this article is to provide an extensive review of the literature discussing the incidence, causative factors, functional impact, classification systems, and treatment of ONF.</p><p><strong>Methods: </strong>A literature review was performed using PubMed using the Medical Subject Heading terms \"cleft palate\" AND \"fistula\" OR \"palatal fistula\" OR \"oronasal fistula\". After review, a total of 356 articles were deemed relevant for this study.</p><p><strong>Results: </strong>Information regarding ONF care, prevention, and management in patients with cleft palate was collected from the articles included in this review. Treatment of ONF remains a challenging problem as there is not a consensus in the available literature on the best palatoplasty techniques for their prevention and treatment. A myriad of reconstructive options and adjunctive therapies exist, and their use is guided by the size and location of the fistula.</p><p><strong>Conclusions: </strong>Fistula treatment should be tailored to the specific needs of the patient, and consideration must be given to not only the ONF itself but also the patient's stage of growth and development. Large-scale, multicenter studies are needed in which ONF are described using standardized nomenclature, and improved outcomes reporting is necessary to better define an algorithm for a truly holistic approach to palate surgery and reduce the incidence of palatal fistula.</p>","PeriodicalId":11687,"journal":{"name":"Eplasty","volume":"23 ","pages":"e7"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912053/pdf/eplasty-23-e7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10825159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge of First Aid Treatment of Burns: A Comparative Study of Parents and Non-parent Adults. 烧伤急救知识:父母与非父母成人的比较研究。
Pub Date : 2023-01-01
Hamna Atique, Hafsa Atique, Sheena Shamoon, Hurmat Fatima Azeem, Syeda Rija Hussain

Background: Burn first aid treatment is any primary care provided for burn injuries prior to medical aid. Children are most vulnerable, with 17% to 18% of childhood burn injuries in Pakistan resulting in disability due to inadequate first aid. Misconceptions and incorrect instant home remedies like toothpastes and burn creams encumber the health care system with preventable ailments. This study aimed to assess and compare the knowledge scores of parents of children under the age of 13 years and non-parent adults regarding burn first aid treatment.

Methods: A cross-sectional descriptive survey was conducted on parents of children under the age of 13 years and non-parent adults. This study included 364 respondents via an online questionnaire; those under the age of 18 years and with previous workshop attendance were excluded. Results were computed in terms of frequencies and comparisons using chi-square test and student t test.

Results: Overall, knowledge among both groups remained inadequate (mean score of 4.18 ± 1.94 out of 14 with parents = 4.20 ± 1.91 and non-parent adults = 4.17 ± 1.98) with no statistically significant difference between the 2 groups (P = 0.841). From a total of 364 respondents, 148 (40.7%) confessed to using toothpaste as the best first aid, while cooling the burn was the most favored immediate step (27.5%). Running with the face covered by a wet towel was considered the safest way of escaping a burning building by 33.8% of respondents.

Conclusions: Both groups were poorly aware of burn first aid treatment, with no superiority of parents over non-parent adults. This highlights the need for educating adults, especially parents, to cater to the prevalent misconceptions in our society and help deliver authentic knowledge regarding first aid management of burns.

背景:烧伤急救治疗是在医疗救助之前为烧伤提供的任何初级护理。儿童是最脆弱的,巴基斯坦17%至18%的儿童烧伤因急救不足而导致残疾。误解和不正确的家庭即时疗法,如牙膏和烧伤膏,阻碍了医疗保健系统的可预防疾病。本研究旨在评估和比较13岁以下儿童父母与非父母成人烧伤急救知识得分。方法:采用横断面描述性调查方法,对13岁以下儿童的父母和无父母的成年人进行调查。该研究通过在线问卷调查了364名受访者;年龄在18岁以下和以前参加过讲习班的人被排除在外。使用卡方检验和学生t检验以频率和比较来计算结果。结果:总体而言,两组患者的知识水平均存在不足(14名父母组= 4.20±1.91,非父母组= 4.17±1.98,平均得分为4.18±1.94),两组间差异无统计学意义(P = 0.841)。在364名受访者中,148人(40.7%)承认使用牙膏是最好的急救措施,而冷却烧伤是最受欢迎的直接措施(27.5%)。33.8%的受访者认为,用湿毛巾蒙住脸跑是逃离燃烧的建筑物最安全的方式。结论:两组患者烧伤急救意识均较差,且父母对非父母成人烧伤急救意识不存在优势。这突出了教育成年人,特别是父母的必要性,以迎合我们社会中普遍存在的误解,并帮助提供有关烧伤急救管理的真实知识。
{"title":"Knowledge of First Aid Treatment of Burns: A Comparative Study of Parents and Non-parent Adults.","authors":"Hamna Atique,&nbsp;Hafsa Atique,&nbsp;Sheena Shamoon,&nbsp;Hurmat Fatima Azeem,&nbsp;Syeda Rija Hussain","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Burn first aid treatment is any primary care provided for burn injuries prior to medical aid. Children are most vulnerable, with 17% to 18% of childhood burn injuries in Pakistan resulting in disability due to inadequate first aid. Misconceptions and incorrect instant home remedies like toothpastes and burn creams encumber the health care system with preventable ailments. This study aimed to assess and compare the knowledge scores of parents of children under the age of 13 years and non-parent adults regarding burn first aid treatment.</p><p><strong>Methods: </strong>A cross-sectional descriptive survey was conducted on parents of children under the age of 13 years and non-parent adults. This study included 364 respondents via an online questionnaire; those under the age of 18 years and with previous workshop attendance were excluded. Results were computed in terms of frequencies and comparisons using chi-square test and student <i>t</i> test.</p><p><strong>Results: </strong>Overall, knowledge among both groups remained inadequate (mean score of 4.18 ± 1.94 out of 14 with parents = 4.20 ± 1.91 and non-parent adults = 4.17 ± 1.98) with no statistically significant difference between the 2 groups (<i>P</i> = 0.841). From a total of 364 respondents, 148 (40.7%) confessed to using toothpaste as the best first aid, while cooling the burn was the most favored immediate step (27.5%). Running with the face covered by a wet towel was considered the safest way of escaping a burning building by 33.8% of respondents.</p><p><strong>Conclusions: </strong>Both groups were poorly aware of burn first aid treatment, with no superiority of parents over non-parent adults. This highlights the need for educating adults, especially parents, to cater to the prevalent misconceptions in our society and help deliver authentic knowledge regarding first aid management of burns.</p>","PeriodicalId":11687,"journal":{"name":"Eplasty","volume":"23 ","pages":"e31"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257203/pdf/eplasty-23-e31.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9621254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Comparative Analysis of Online Reporting of Possible Complications for Minimally Invasive Cosmetic Procedures. 微创美容手术并发症在线报告的比较分析。
Pub Date : 2023-01-01
Anooj A Patel, Stuti P Garg, Jeffrey Varghese, Brendan Alleyne, Tokoya Williams, Kristin Huffman, Marco Ellis, Robert D Galiano

Background: The rise in Botox, fillers, and chemical peel procedures demands transparent online information that discloses all relevant risks and complications. This study assesses the quality of complication disclosure on the most popular cosmetic sites.

Methods: The top 50 Google search results for "Botox," "fillers," and "chemical peel" were analyzed for their reporting on relevant complications. Websites were categorized based on their origin. An overall complication, prevention, management, prevalence, and disclaimer score were assigned to each site.

Results: A total of 136 websites were analyzed. Of these websites, 31 (22.7%) did not mention any complications or risks associated with the treatment. The most commonly reported complications were bruising (67.0%) for Botox, swelling (79.0%) for fillers, and redness (58%) for chemical peels. The least-reported serious complications were toxin spread effects (31.0%) for Botox, vision loss (23.0%) for fillers, and allergic reaction for chemical peel (18.0%). Reports of serious and rare side effects were significantly lower than those of common side effects (Botox, P = .001; fillers, P = .004; chemical peels, P < .001). The overall mean (standard deviation) complication score across all websites was 2.81/5 (1.31). Online health reference and academic/hospital sites disclosed complications better than sources in most other categories (P < .001).

Conclusions: The reporting of online complications for the top 3 cosmetic procedures performed in the US is highly variable, biased, and at times, completely absent. Patients pursuing cosmetic surgery are heavily influenced by the internet and vulnerable to misinformation. Cosmetic procedure websites are in need of drastic improvement to ensure the health and safety of all patients.

背景:肉毒杆菌、填充物和化学去皮手术的增加需要透明的在线信息,披露所有相关的风险和并发症。本研究评估了最受欢迎的美容网站并发症披露的质量。方法:对谷歌搜索“肉毒杆菌”、“填充物”和“化学去皮”的前50名搜索结果进行分析,分析其相关并发症的报道。网站是根据来源分类的。对每个部位进行并发症、预防、管理、患病率和免责评分。结果:共分析了136个网站。在这些网站中,31个(22.7%)没有提及任何与治疗相关的并发症或风险。最常见的并发症是肉毒杆菌毒素引起的瘀伤(67.0%),填充物引起的肿胀(79.0%)和化学换肤引起的红肿(58%)。报告最少的严重并发症是肉毒杆菌毒素扩散效应(31.0%),填充物视力下降(23.0%)和化学剥皮过敏反应(18.0%)。报告的严重和罕见的副作用显著低于常见的副作用(肉毒杆菌,P = .001;填料,P = 0.004;化学脱皮,P < 0.001)。各部位并发症的总平均(标准差)评分为2.81/5(1.31)。在线健康参考和学术/医院网站比大多数其他类别的来源更容易披露并发症(P < 0.001)。结论:在美国进行的前3种美容手术的在线并发症报告是高度可变的,有偏见的,有时完全没有。寻求整容手术的患者受到互联网的严重影响,容易受到错误信息的影响。整容网站需要大幅改进,以确保所有患者的健康和安全。
{"title":"A Comparative Analysis of Online Reporting of Possible Complications for Minimally Invasive Cosmetic Procedures.","authors":"Anooj A Patel,&nbsp;Stuti P Garg,&nbsp;Jeffrey Varghese,&nbsp;Brendan Alleyne,&nbsp;Tokoya Williams,&nbsp;Kristin Huffman,&nbsp;Marco Ellis,&nbsp;Robert D Galiano","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The rise in Botox, fillers, and chemical peel procedures demands transparent online information that discloses all relevant risks and complications. This study assesses the quality of complication disclosure on the most popular cosmetic sites.</p><p><strong>Methods: </strong>The top 50 Google search results for \"Botox,\" \"fillers,\" and \"chemical peel\" were analyzed for their reporting on relevant complications. Websites were categorized based on their origin. An overall complication, prevention, management, prevalence, and disclaimer score were assigned to each site.</p><p><strong>Results: </strong>A total of 136 websites were analyzed. Of these websites, 31 (22.7%) did not mention any complications or risks associated with the treatment. The most commonly reported complications were bruising (67.0%) for Botox, swelling (79.0%) for fillers, and redness (58%) for chemical peels. The least-reported serious complications were toxin spread effects (31.0%) for Botox, vision loss (23.0%) for fillers, and allergic reaction for chemical peel (18.0%). Reports of serious and rare side effects were significantly lower than those of common side effects (Botox, <i>P</i> = .001; fillers, <i>P</i> = .004; chemical peels, <i>P</i> < .001). The overall mean (standard deviation) complication score across all websites was 2.81/5 (1.31). Online health reference and academic/hospital sites disclosed complications better than sources in most other categories (<i>P</i> < .001).</p><p><strong>Conclusions: </strong>The reporting of online complications for the top 3 cosmetic procedures performed in the US is highly variable, biased, and at times, completely absent. Patients pursuing cosmetic surgery are heavily influenced by the internet and vulnerable to misinformation. Cosmetic procedure websites are in need of drastic improvement to ensure the health and safety of all patients.</p>","PeriodicalId":11687,"journal":{"name":"Eplasty","volume":"23 ","pages":"e17"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176491/pdf/eplasty-23-e17.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9829687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: Closed Incision Negative Pressure Therapy Versus Standard of Care Over Closed Plastic Surgery Incisions in the Reduction of Surgical Site Complications: A Systematic Review and Meta-Analysis of Comparative Studies. 修正:闭合切口负压治疗与闭合整形手术切口的标准护理在减少手术部位并发症方面:比较研究的系统回顾和荟萃分析。
Pub Date : 2023-01-01

[This corrects the article e22 in vol. 23, PMID: 37187870.].

[这更正了第23卷中的文章e22, PMID: 37187870]。
{"title":"Correction to: Closed Incision Negative Pressure Therapy Versus Standard of Care Over Closed Plastic Surgery Incisions in the Reduction of Surgical Site Complications: A Systematic Review and Meta-Analysis of Comparative Studies.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>[This corrects the article e22 in vol. 23, PMID: 37187870.].</p>","PeriodicalId":11687,"journal":{"name":"Eplasty","volume":"23 ","pages":"er1"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478828/pdf/eplasty-23-er1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10172981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Barrier Functions of the Skin. 皮肤的屏障功能。
Pub Date : 2023-01-01
Stephen M Milner
{"title":"Barrier Functions of the Skin.","authors":"Stephen M Milner","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11687,"journal":{"name":"Eplasty","volume":"23 ","pages":"QA6"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254769/pdf/eplasty-23-QA6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9621250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autologous Breast Reconstruction in a Patient With End-Stage Renal Disease and Systemic Lupus Erythematosus. 终末期肾病合并系统性红斑狼疮患者自体乳房重建术1例。
Pub Date : 2023-01-01
Max Mandelbaum, Alexandra Townsend, Stefani Fontana, Marco Harmaty, Philip Torina

Background: Patients with end-stage renal disease (ESRD) secondary to systemic lupus erythematosus (SLE) have historically been deterred from free flap breast reconstruction due to perceived complication risks. Numerous studies examining patients with ESRD have cited free flap complications, including increased incidences of infection and wound breakdown, with some surgeons suggesting ESRD is an independent risk factor for flap failure.15 Due to perceived risks, autologous breast reconstruction has not been extensively explored as an option in patients with ESRD on hemodialysis with comorbid connective tissue/autoimmune disorders, such as SLE. To the authors' knowledge, there are currently no published reports of successful free flap breast reconstruction in patients with ESRD due to SLE.

Methods: This case report describes a patient requiring hemodialysis for ESRD caused by SLE who underwent left mastectomy and immediate autologous breast reconstruction. Deep inferior epigastric perforator flap technique was employed.

Conclusions: This successful case report suggests the use of free flaps is a feasible option that should be considered for oncologic breast reconstruction in patients with ESRD secondary to SLE who require hemodialysis. The authors believe that further investigation is warranted to evaluate the safety of autologous breast reconstruction as an option for patients with either comorbidity. While ESRD and SLE are not explicit contraindications to free flap reconstruction, careful patient selection and appropriate indication is paramount for immediate surgical and long-term reconstructive success.

背景:继发于系统性红斑狼疮(SLE)的终末期肾脏疾病(ESRD)患者历来因并发症风险而不愿进行游离皮瓣乳房重建术。许多关于ESRD患者的研究都引用了游离皮瓣并发症,包括感染和伤口破裂的发生率增加,一些外科医生认为ESRD是皮瓣失败的独立危险因素由于可感知的风险,自体乳房重建尚未被广泛探索作为ESRD血液透析合并结缔组织/自身免疫性疾病(如SLE)患者的选择。据作者所知,目前尚无关于SLE所致ESRD患者游离皮瓣乳房重建成功的报道。方法:本病例报告描述了一例因SLE引起的ESRD需要血液透析的患者,该患者接受了左乳房切除术和立即自体乳房重建。采用深下腹壁穿支皮瓣技术。结论:这一成功的病例报告表明,对于需要血液透析的SLE继发ESRD患者,使用游离皮瓣是一种可行的选择。作者认为,进一步的研究是有必要的,以评估自体乳房重建的安全性,作为一个选择的患者有任何合并症。虽然ESRD和SLE不是游离皮瓣重建的明确禁忌症,但谨慎的患者选择和适当的适应症对于立即手术和长期重建的成功至关重要。
{"title":"Autologous Breast Reconstruction in a Patient With End-Stage Renal Disease and Systemic Lupus Erythematosus.","authors":"Max Mandelbaum,&nbsp;Alexandra Townsend,&nbsp;Stefani Fontana,&nbsp;Marco Harmaty,&nbsp;Philip Torina","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Patients with end-stage renal disease (ESRD) secondary to systemic lupus erythematosus (SLE) have historically been deterred from free flap breast reconstruction due to perceived complication risks. Numerous studies examining patients with ESRD have cited free flap complications, including increased incidences of infection and wound breakdown, with some surgeons suggesting ESRD is an independent risk factor for flap failure.<sup>15</sup> Due to perceived risks, autologous breast reconstruction has not been extensively explored as an option in patients with ESRD on hemodialysis with comorbid connective tissue/autoimmune disorders, such as SLE. To the authors' knowledge, there are currently no published reports of successful free flap breast reconstruction in patients with ESRD due to SLE.</p><p><strong>Methods: </strong>This case report describes a patient requiring hemodialysis for ESRD caused by SLE who underwent left mastectomy and immediate autologous breast reconstruction. Deep inferior epigastric perforator flap technique was employed.</p><p><strong>Conclusions: </strong>This successful case report suggests the use of free flaps is a feasible option that should be considered for oncologic breast reconstruction in patients with ESRD secondary to SLE who require hemodialysis. The authors believe that further investigation is warranted to evaluate the safety of autologous breast reconstruction as an option for patients with either comorbidity. While ESRD and SLE are not explicit contraindications to free flap reconstruction, careful patient selection and appropriate indication is paramount for immediate surgical and long-term reconstructive success.</p>","PeriodicalId":11687,"journal":{"name":"Eplasty","volume":"23 ","pages":"e29"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257201/pdf/eplasty-23-e29.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9621256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How to Select an Extracellular Matrix for Wound Repair: A Comprehensive Review. 如何选择用于伤口修复的细胞外基质:综述。
Pub Date : 2023-01-01
Samuel Stetkevich, Monik Gupta, Richard Simman, Sarah E Jackson

Background: An extracellular matrix (ECM) is a network of proteins and other molecules that provide support and structure to cells and tissues in the body. Since its discovery in 1930, researchers have reproduced the ECM through an array of evolving technologies, developing products that accelerate healing times, minimize scarring, and reduce pain. When selecting which ECM product to use, physicians rely on personal experience while considering wound location, type of tissue lost, exposed structures, chronicity, and even the patient's religious preferences. While comparison trials between a few different types of ECMs exist, there lacks a thorough investigation that assesses a majority of ECMs against each other.

Methods: Herein, we conducted a literature review using the PubMed database and utilized 71 articles to identify the best ECM for wound healing and positive patient outcomes. The primary search terms included extracellular matrix, xenograft, porcine, bovine, allograft, bioengineered matrix, acellularized fish skin, wounds, wound healing, and wound care. We did not exclude any specific type of research, but predominantly reviewed clinical trials, case series, and other review articles. We focused on the most popular and commonly used ECMs and constructed our results into the Table.

Results: We compared the indications, advantages, and disadvantages of each ECM and concisely illustrated these findings to provide a guide on how to select an ECM (Table). Allografts, whether they are glycerol or cryopreserved, suffice as a treatment choice and are superior to exposure healing. However, they do not produce healing at the same rate or quality as bioengineered matrices, porcine and bovine xenografts, or acellularized fish skin (AFS). Bioengineered matrices and porcine and bovine xenografts offer antimicrobial properties, low immunogenicity, cost effectiveness, and availability. The compromise with these ECMs is with healing times and cosmesis. Acellularized fish skin (AFS) provides diverse utility, antimicrobial activity, low immunogenicity, faster healing times, and cosmetic superiority. However, AFS yields a potential cost burden and is not plentiful or easily accessible in some parts of the world.

Conclusions: Our findings assist in removing the subjectivity component of selecting an ECM and suggest further comparison or head-to-head trials would yield a more algorithmic approach to wound healing. We suggest to consider implementing the Disabilities of the Arm, Shoulder, and Hand (DASH) score as an additional objective comparison method in these future trials.

背景:细胞外基质(ECM)是由蛋白质和其他分子组成的网络,为体内的细胞和组织提供支持和结构。自1930年发现ECM以来,研究人员通过一系列不断发展的技术复制了ECM,开发了加速愈合时间、减少疤痕和减轻疼痛的产品。在选择使用何种ECM产品时,医生会根据个人经验,同时考虑伤口位置、组织丢失类型、暴露结构、慢性程度,甚至患者的宗教偏好。虽然存在几种不同类型ecm之间的比较试验,但缺乏对大多数ecm彼此进行评估的彻底调查。方法:在此,我们使用PubMed数据库进行了文献综述,并利用71篇文章来确定伤口愈合的最佳ECM和积极的患者预后。主要搜索词包括细胞外基质、异种移植物、猪、牛、同种异体移植物、生物工程基质、脱细胞鱼皮、伤口、伤口愈合和伤口护理。我们没有排除任何特定类型的研究,但主要回顾了临床试验、病例系列和其他综述文章。我们将重点放在最流行和最常用的ecm上,并将结果构建到该表中。结果:我们比较了每种ECM的适应症、优缺点,并简要说明了这些发现,为如何选择ECM提供了指导(表)。同种异体移植,无论是甘油还是冷冻保存,都足以作为一种治疗选择,并且优于暴露愈合。然而,它们产生愈合的速度和质量不如生物工程基质、猪和牛异种移植或脱细胞鱼皮(AFS)。生物工程基质和猪和牛异种移植物具有抗菌特性、低免疫原性、成本效益和可用性。与这些ecm的妥协是治疗时间和美容。脱细胞鱼皮(AFS)具有多种用途,抗菌活性,低免疫原性,更快的愈合时间和美容优势。然而,AFS产生了潜在的成本负担,而且在世界某些地区并不充足或不易获得。结论:我们的研究结果有助于消除选择ECM的主观性因素,并建议进一步的比较或头对头试验将产生更算法的伤口愈合方法。我们建议在未来的试验中考虑采用手臂、肩膀和手的残疾(DASH)评分作为额外的客观比较方法。
{"title":"How to Select an Extracellular Matrix for Wound Repair: A Comprehensive Review.","authors":"Samuel Stetkevich,&nbsp;Monik Gupta,&nbsp;Richard Simman,&nbsp;Sarah E Jackson","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>An extracellular matrix (ECM) is a network of proteins and other molecules that provide support and structure to cells and tissues in the body. Since its discovery in 1930, researchers have reproduced the ECM through an array of evolving technologies, developing products that accelerate healing times, minimize scarring, and reduce pain. When selecting which ECM product to use, physicians rely on personal experience while considering wound location, type of tissue lost, exposed structures, chronicity, and even the patient's religious preferences. While comparison trials between a few different types of ECMs exist, there lacks a thorough investigation that assesses a majority of ECMs against each other.</p><p><strong>Methods: </strong>Herein, we conducted a literature review using the PubMed database and utilized 71 articles to identify the best ECM for wound healing and positive patient outcomes. The primary search terms included <i>extracellular matrix, xenograft, porcine, bovine, allograft, bioengineered matrix, acellularized fish skin, wounds, wound healing,</i> and <i>wound care.</i> We did not exclude any specific type of research, but predominantly reviewed clinical trials, case series, and other review articles. We focused on the most popular and commonly used ECMs and constructed our results into the <b>Table</b>.</p><p><strong>Results: </strong>We compared the indications, advantages, and disadvantages of each ECM and concisely illustrated these findings to provide a guide on how to select an ECM <b>(Table).</b> Allografts, whether they are glycerol or cryopreserved, suffice as a treatment choice and are superior to exposure healing. However, they do not produce healing at the same rate or quality as bioengineered matrices, porcine and bovine xenografts, or acellularized fish skin (AFS). Bioengineered matrices and porcine and bovine xenografts offer antimicrobial properties, low immunogenicity, cost effectiveness, and availability. The compromise with these ECMs is with healing times and cosmesis. Acellularized fish skin (AFS) provides diverse utility, antimicrobial activity, low immunogenicity, faster healing times, and cosmetic superiority. However, AFS yields a potential cost burden and is not plentiful or easily accessible in some parts of the world.</p><p><strong>Conclusions: </strong>Our findings assist in removing the subjectivity component of selecting an ECM and suggest further comparison or head-to-head trials would yield a more algorithmic approach to wound healing. We suggest to consider implementing the Disabilities of the Arm, Shoulder, and Hand (DASH) score as an additional objective comparison method in these future trials.</p>","PeriodicalId":11687,"journal":{"name":"Eplasty","volume":"23 ","pages":"e51"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472439/pdf/eplasty-23-e51.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10150951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potent Micrografting Using the Meek Technique for Knee Joint Wound Reconstruction. Meek技术在膝关节创面重建中的应用。
Pub Date : 2023-01-01
Michika Fukui, Masakatsu Hihara, Kota Takeji, Yuki Matsuoka, Maki Okamoto, Maako Fujita, Natsuko Kakudo

Background: Efficient treatment of extensive skin defects by using skin grafting is a significant challenge because the skin available to use is limited. A mesh graft is usually used; however, the expansion ratio is small (up to 1:6) and inaccurate. The Meek technique is a method of skin grafting that processes the skin into micrografts by cutting. The advantage of the Meek technique is its efficient use of available skin, expanding its area by up to 9 times. In 2020, Japanese insurance companies began to cover treatment using the Meek technique. This report aimed to show the usefulness of the Meek technique for treating left leg necrotizing fasciitis.

Methods: A 55-year-old male was referred to our hospital for treating necrotizing fasciitis of the left leg. Debridement was performed, and antibiotics were administered immediately. After 1 month, Meek micrografts were applied to the left knee wound. The expansion ratio of the Meek micrografts was 1:9.

Results: The skin was processed 9 times using the Meek technique, enabling effective use of a small amount of skin. Epithelialization of the Meek micrograft area was completed 1 month after skin grafting. The scar after Meek micrografting was soft and not reddish. The range of motion of the knee joint was >90 degrees.

Conclusions: The Meek technique allows expansion of limited skin efficiently. Meek micrografts can cover a larger wound with smaller skin grafts than is possible with mesh grafts. After healing with Meek micrografts, the scar was soft, and the knee joint flexed smoothly. The Meek technique is useful for treating large wounds requiring skin grafts.

背景:由于可供使用的皮肤有限,利用皮肤移植有效治疗大面积皮肤缺损是一个重大挑战。通常使用网状移植物;然而,膨胀比很小(可达1:6)且不准确。Meek技术是一种皮肤移植方法,通过切割将皮肤加工成微移植物。Meek技术的优势在于它有效地利用了可用的皮肤,将其面积扩大了9倍。2020年,日本保险公司开始为使用Meek技术的治疗提供保险。本报告旨在展示Meek技术治疗左腿坏死性筋膜炎的有效性。方法:患者为55岁男性,因左腿坏死性筋膜炎入院治疗。进行清创,并立即使用抗生素。1个月后,将Meek微移植物应用于左膝创面。Meek微移植物的扩张比为1:9。结果:使用Meek技术对皮肤进行了9次处理,使少量皮肤得到有效利用。皮肤移植后1个月完成Meek微移植物区的上皮化。Meek显微移植后瘢痕柔软,不发红。膝关节活动范围>90度。结论:Meek技术可以有效地扩展有限的皮肤。柔嫩的微移植物可以用更小的皮肤移植物覆盖更大的伤口,而不是用网状移植物。Meek微移植物愈合后,瘢痕柔软,膝关节柔韧。Meek技术适用于需要植皮的大伤口。
{"title":"Potent Micrografting Using the Meek Technique for Knee Joint Wound Reconstruction.","authors":"Michika Fukui,&nbsp;Masakatsu Hihara,&nbsp;Kota Takeji,&nbsp;Yuki Matsuoka,&nbsp;Maki Okamoto,&nbsp;Maako Fujita,&nbsp;Natsuko Kakudo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Efficient treatment of extensive skin defects by using skin grafting is a significant challenge because the skin available to use is limited. A mesh graft is usually used; however, the expansion ratio is small (up to 1:6) and inaccurate. The Meek technique is a method of skin grafting that processes the skin into micrografts by cutting. The advantage of the Meek technique is its efficient use of available skin, expanding its area by up to 9 times. In 2020, Japanese insurance companies began to cover treatment using the Meek technique. This report aimed to show the usefulness of the Meek technique for treating left leg necrotizing fasciitis.</p><p><strong>Methods: </strong>A 55-year-old male was referred to our hospital for treating necrotizing fasciitis of the left leg. Debridement was performed, and antibiotics were administered immediately. After 1 month, Meek micrografts were applied to the left knee wound. The expansion ratio of the Meek micrografts was 1:9.</p><p><strong>Results: </strong>The skin was processed 9 times using the Meek technique, enabling effective use of a small amount of skin. Epithelialization of the Meek micrograft area was completed 1 month after skin grafting. The scar after Meek micrografting was soft and not reddish. The range of motion of the knee joint was >90 degrees.</p><p><strong>Conclusions: </strong>The Meek technique allows expansion of limited skin efficiently. Meek micrografts can cover a larger wound with smaller skin grafts than is possible with mesh grafts. After healing with Meek micrografts, the scar was soft, and the knee joint flexed smoothly. The Meek technique is useful for treating large wounds requiring skin grafts.</p>","PeriodicalId":11687,"journal":{"name":"Eplasty","volume":"23 ","pages":"e14"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008300/pdf/eplasty-23-e14.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9122729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tissue Expander for Pediatric Scalp Reconstruction Complicated by Fungal Infection With Aspergillus terreus. 组织扩张器用于儿童头皮重建并发地曲霉真菌感染。
Pub Date : 2023-01-01
Shelley R Edwards, Katherine C Benedict, John Sullivan, Roberto Santos, Ian Hoppe

Background: Tissue expansion is an effective option for soft tissue reconstruction of the scalp in the pediatric population. Unfortunately, this approach carries a high risk of such complications as infection and expander exposure. While bacterial infection of alloplastic materials is most frequent, when fungal infections occur, the outcomes can be devastating.

Purpose: To inform the management of fungal tissue expander infections, this report describes a case of expander-based scalp reconstruction complicated by Aspergillus terreus infection in a pediatric patient.

Methods: A patient who had blunt-force head trauma presented with soft tissue injury and depressed skull fracture requiring emergent craniectomy. After stabilization, a paucity of soft tissue coverage required further surgical intervention before reconstructive cranioplasty. Six months after her injury, two remote port subgaleal tissue expanders were placed. Subsequently, purulent drainage developed from the surgical incision.

Results: Infection resulted in expander exposure requiring device removal and treatment with clindamycin and ceftazidime while awaiting culture results. Intraoperative cultures were positive for Aspergillus terreus and methicillin-sensitive Staphylococcus aureus, for which she received systemic voriconazole for 23 days and cephalexin for 10 days.

Conclusions: Though tissue expansion remains a viable reconstructive option, fungal infection can be disastrous, requiring systemic antifungal therapy, surgical debridement, and expander removal.

背景:组织扩张是儿童头皮软组织重建的有效选择。不幸的是,这种方法有很高的并发症风险,如感染和扩张器暴露。虽然同种异体材料的细菌感染是最常见的,但当真菌感染发生时,结果可能是毁灭性的。目的:为了解真菌组织扩张器感染的处理方法,本报告描述了一例以扩张器为基础的头皮重建并发地曲霉感染的儿科患者。方法:1例钝力颅脑外伤患者以软组织损伤和凹陷性颅骨骨折为主要表现,需要紧急开颅手术。稳定后,由于软组织覆盖不足,需要在重建颅骨成形术前进行进一步的手术干预。在她受伤六个月后,放置了两个远端半裂片下组织扩张器。随后,手术切口出现脓性引流。结果:感染导致扩张器暴露,需要取出扩张器并给予克林霉素和头孢他啶治疗,同时等待培养结果。术中培养为地曲霉和甲氧西林敏感金黄色葡萄球菌阳性,患者全身接受伏立康唑治疗23天,头孢氨苄治疗10天。结论:虽然组织扩张仍然是一种可行的重建选择,但真菌感染可能是灾难性的,需要全身抗真菌治疗、手术清创和取出扩张器。
{"title":"Tissue Expander for Pediatric Scalp Reconstruction Complicated by Fungal Infection With Aspergillus terreus.","authors":"Shelley R Edwards,&nbsp;Katherine C Benedict,&nbsp;John Sullivan,&nbsp;Roberto Santos,&nbsp;Ian Hoppe","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Tissue expansion is an effective option for soft tissue reconstruction of the scalp in the pediatric population. Unfortunately, this approach carries a high risk of such complications as infection and expander exposure. While bacterial infection of alloplastic materials is most frequent, when fungal infections occur, the outcomes can be devastating.</p><p><strong>Purpose: </strong>To inform the management of fungal tissue expander infections, this report describes a case of expander-based scalp reconstruction complicated by <i>Aspergillus terreus</i> infection in a pediatric patient.</p><p><strong>Methods: </strong>A patient who had blunt-force head trauma presented with soft tissue injury and depressed skull fracture requiring emergent craniectomy. After stabilization, a paucity of soft tissue coverage required further surgical intervention before reconstructive cranioplasty. Six months after her injury, two remote port subgaleal tissue expanders were placed. Subsequently, purulent drainage developed from the surgical incision.</p><p><strong>Results: </strong>Infection resulted in expander exposure requiring device removal and treatment with clindamycin and ceftazidime while awaiting culture results. Intraoperative cultures were positive for <i>Aspergillus terreus</i> and methicillin-sensitive <i>Staphylococcus aureus,</i> for which she received systemic voriconazole for 23 days and cephalexin for 10 days.</p><p><strong>Conclusions: </strong>Though tissue expansion remains a viable reconstructive option, fungal infection can be disastrous, requiring systemic antifungal therapy, surgical debridement, and expander removal.</p>","PeriodicalId":11687,"journal":{"name":"Eplasty","volume":"23 ","pages":"e9"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008302/pdf/eplasty-23-e9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9122731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Eplasty
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1