Pub Date : 2025-12-26DOI: 10.1007/s10654-025-01351-5
Albert Hofman
{"title":"A note of thanks","authors":"Albert Hofman","doi":"10.1007/s10654-025-01351-5","DOIUrl":"https://doi.org/10.1007/s10654-025-01351-5","url":null,"abstract":"","PeriodicalId":11907,"journal":{"name":"European Journal of Epidemiology","volume":"32 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145830269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-13DOI: 10.1007/s10654-025-01312-y
Ellen E Walters,Susan E Luczak,Christopher R Beam,Malin Ericsson,William S Kremen,Robert F Krueger,Kristian E Markon,Matt McGue,Marianne Nygaard,Matthew S Panizzon,Brenda L Plassman,Chandra A Reynolds,Perminder S Sachdev,Anbu Thalamuthu,Keith E Whitfield,Nancy L Pedersen,Margaret Gatz,
We reply to the letter to the editor by Soohyeon Ko (Eur J Epidemiol, https://doi.org/10.1007/s10654-025-01305-x ) concerning our article by Walters et al. (Eur J Epidemiol, https://doi.org/10.1007/s10654-025-01286-x ). We reiterate that genetic explanations contribute to understanding why education is protective against dementia, alongside influences reflecting the whole of one's family and societal context. We also caution that genetic explanations should not be misinterpreted as deterministic.
我们回复了Soohyeon Ko （Eur J epidemiology, https://doi.org/10.1007/s10654-025-01305-x）就Walters et al. （Eur J epidemiology, https://doi.org/10.1007/s10654-025-01286-x）的文章给编辑的信。我们重申，基因解释有助于理解为什么教育可以预防痴呆症，以及反映整个家庭和社会背景的影响。我们还警告说，基因解释不应被误解为决定性的。
{"title":"Reply to Ko, Null within-twin estimates on education and dementia: cautions for within-family contrasts.","authors":"Ellen E Walters,Susan E Luczak,Christopher R Beam,Malin Ericsson,William S Kremen,Robert F Krueger,Kristian E Markon,Matt McGue,Marianne Nygaard,Matthew S Panizzon,Brenda L Plassman,Chandra A Reynolds,Perminder S Sachdev,Anbu Thalamuthu,Keith E Whitfield,Nancy L Pedersen,Margaret Gatz, ","doi":"10.1007/s10654-025-01312-y","DOIUrl":"https://doi.org/10.1007/s10654-025-01312-y","url":null,"abstract":"We reply to the letter to the editor by Soohyeon Ko (Eur J Epidemiol, https://doi.org/10.1007/s10654-025-01305-x ) concerning our article by Walters et al. (Eur J Epidemiol, https://doi.org/10.1007/s10654-025-01286-x ). We reiterate that genetic explanations contribute to understanding why education is protective against dementia, alongside influences reflecting the whole of one's family and societal context. We also caution that genetic explanations should not be misinterpreted as deterministic.","PeriodicalId":11907,"journal":{"name":"European Journal of Epidemiology","volume":"1 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145732661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-03DOI: 10.1007/s10654-025-01301-1
Marco Piccininni, Vanessa Didelez, Mats J. Stensrud
Screening colonoscopy has been shown to reduce colorectal cancer incidence. However, the magnitude of this effect is debated. There is concern that some trial participants already had colorectal cancer at baseline. The screening procedure could not prevent disease occurrence in these participants, leading to “prevalence bias”. Some authors have argued that the effect of interest is confined to participants without disease at baseline, and failing to exclude prevalent cases supposedly leads to effect underestimation. Yet, the issue is debated, with other authors arguing that conventional randomized trials provide the effects that are most relevant to public health. Here we present new, formal arguments that clarify misconceptions in this debate. We show that, under mild assumptions, the so-called “prevalence bias” is not a concern when researchers are interested in estimating risk differences, rather than risk ratios. This is because of a statistical property of the causal risk difference when outcomes are rare, called “doomed-selection stability”.
{"title":"Choosing a sensible contrast makes “prevalence bias” irrelevant in screening colonoscopy trials","authors":"Marco Piccininni, Vanessa Didelez, Mats J. Stensrud","doi":"10.1007/s10654-025-01301-1","DOIUrl":"https://doi.org/10.1007/s10654-025-01301-1","url":null,"abstract":"Screening colonoscopy has been shown to reduce colorectal cancer incidence. However, the magnitude of this effect is debated. There is concern that some trial participants already had colorectal cancer at baseline. The screening procedure could not prevent disease occurrence in these participants, leading to “prevalence bias”. Some authors have argued that the effect of interest is confined to participants without disease at baseline, and failing to exclude prevalent cases supposedly leads to effect underestimation. Yet, the issue is debated, with other authors arguing that conventional randomized trials provide the effects that are most relevant to public health. Here we present new, formal arguments that clarify misconceptions in this debate. We show that, under mild assumptions, the so-called “prevalence bias” is not a concern when researchers are interested in estimating risk differences, rather than risk ratios. This is because of a statistical property of the causal risk difference when outcomes are rare, called “doomed-selection stability”.","PeriodicalId":11907,"journal":{"name":"European Journal of Epidemiology","volume":"58 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145657358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-09-01DOI: 10.1007/s10654-025-01295-w
Yunyun Liu, Chi Pang Wen, Junlong Pan, Jiameng Cui, Wanzhu Lu, Tong Sun, Xian Ning, June Han Lee, Wenyuan Li, Huakang Tu, Xifeng Wu
Previous studies on serum iron levels and mortality risk have yielded inconsistent findings based on single-point measurements. How serum iron levels and their longitudinal changes influence all-cause and cause-specific mortality remains unknown. This study investigated associations between baseline serum iron levels, their longitudinal changes, and all-cause and cause-specific mortality in a prospective cohort. Participants were recruited from the Taiwan MJ cohort (1997-2007) and followed until December 31, 2022. Baseline serum iron was categorized as low, normal, or high. Based on changes at a second visit, participants were further classified as persistent normal, progression to abnormal, reversion to normal, or persistent abnormal. Cox proportional hazard models were used for analysis. Over a median follow-up of 19.0 years, 33,005 deaths occurred. Fully adjusted models demonstrated J-shaped associations between serum iron and all-cause and cause-specific mortality (all P < 0.001), with higher all-cause mortality risks in low (HR 1.27, 95% CI [1.23, 1.31]) and high iron groups (HR 1.37, 95% CI [1.30, 1.44]). Compared to persistent normal levels, those with progression to abnormal, reversion to normal, or persistent abnormal serum iron exhibited elevated mortality risks (HRs: 1.22 [1.15, 1.30], 1.16 [1.09, 1.24], 1.49 [1.36, 1.63], respectively). Moreover, maintaining normal serum iron status alongside a healthy lifestyle exhibited the lowest mortality risks. Long term abnormal serum iron status was linked to increased mortality, which could be mitigated through lifestyle modifications, suggesting significance of serum iron monitoring and potential intervention.
{"title":"Associations of serum iron and its status change with mortality risk: prospective findings from the MJ cohort.","authors":"Yunyun Liu, Chi Pang Wen, Junlong Pan, Jiameng Cui, Wanzhu Lu, Tong Sun, Xian Ning, June Han Lee, Wenyuan Li, Huakang Tu, Xifeng Wu","doi":"10.1007/s10654-025-01295-w","DOIUrl":"10.1007/s10654-025-01295-w","url":null,"abstract":"<p><p>Previous studies on serum iron levels and mortality risk have yielded inconsistent findings based on single-point measurements. How serum iron levels and their longitudinal changes influence all-cause and cause-specific mortality remains unknown. This study investigated associations between baseline serum iron levels, their longitudinal changes, and all-cause and cause-specific mortality in a prospective cohort. Participants were recruited from the Taiwan MJ cohort (1997-2007) and followed until December 31, 2022. Baseline serum iron was categorized as low, normal, or high. Based on changes at a second visit, participants were further classified as persistent normal, progression to abnormal, reversion to normal, or persistent abnormal. Cox proportional hazard models were used for analysis. Over a median follow-up of 19.0 years, 33,005 deaths occurred. Fully adjusted models demonstrated J-shaped associations between serum iron and all-cause and cause-specific mortality (all P < 0.001), with higher all-cause mortality risks in low (HR 1.27, 95% CI [1.23, 1.31]) and high iron groups (HR 1.37, 95% CI [1.30, 1.44]). Compared to persistent normal levels, those with progression to abnormal, reversion to normal, or persistent abnormal serum iron exhibited elevated mortality risks (HRs: 1.22 [1.15, 1.30], 1.16 [1.09, 1.24], 1.49 [1.36, 1.63], respectively). Moreover, maintaining normal serum iron status alongside a healthy lifestyle exhibited the lowest mortality risks. Long term abnormal serum iron status was linked to increased mortality, which could be mitigated through lifestyle modifications, suggesting significance of serum iron monitoring and potential intervention.</p>","PeriodicalId":11907,"journal":{"name":"European Journal of Epidemiology","volume":" ","pages":"1419-1429"},"PeriodicalIF":5.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144947616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-28DOI: 10.1007/s10654-025-01328-4
Paolo Vineis
{"title":"Causality and exposome","authors":"Paolo Vineis","doi":"10.1007/s10654-025-01328-4","DOIUrl":"https://doi.org/10.1007/s10654-025-01328-4","url":null,"abstract":"","PeriodicalId":11907,"journal":{"name":"European Journal of Epidemiology","volume":"32 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145611107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-24DOI: 10.1007/s10654-025-01314-w
Mark P. Little, Jim Z. Mai, Jill S. Barnholtz-Sloan, Martha S. Linet, Michelle Fang, Pavel Chernyavskiy, Victoria Kennerley, Elizabeth K. Cahoon, Myles G. Cockburn, Gerald M. Kendall, Michael G. Kimlin
Brain tumour is the second most common type of childhood cancer and the most common solid tumour in children, but its aetiology is largely unknown. Some previous studies have suggested that elevated ultraviolet radiation (UVR) exposures decrease brain tumour risk, but the evidence is inconsistent. We conducted a cross-sectional study (with census-derived population counts) to assess age < 20 malignant/non-malignant brain tumour incidence overall and for major categories in Surveillance, Epidemiology and End Results 2000–2021 data, using ground-based UVR-irradiance measures, via quasi-likelihood models accounting for over/under-dispersion, adjusted for age, sex, race/ethnicity and other socioeconomic variables. There were 29,088/18,585 cases of malignant/non-malignant brain tumour, with generally significant decreasing trends of both types of tumour with UVR irradiance [relative risk (RR) = 0.754/mW/cm 2 (95% CI 0.659, 0.862, p < 0.0001) for malignant brain tumour, RR = 0.466/mW/cm 2 (95% CI 0.382, 0.567, p < 0.0001] for non-malignant brain tumour), although there was significant heterogeneity by histopathologic subtype, race/ethnicity, and sex. Equally, there is a highly significant decreasing trend of both types of tumour with UVR-cumulative radiant exposure ( p < 0.0001). These trends are also significant in many malignant/non-malignant brain tumour histopathological subtypes and racial/ethnic groups. However, there are certain non-malignant brain tumour subtypes, for example tumours of the pineal region and meningeal tumours, where RR significantly exceed 1 in relation to UVR irradiance ( p = 0.0330, p = 0.0024 respectively). Our finding, of a generally protective effect of UVR on brain tumour risk is not clear-cut, and warrants large studies of specific histopathological pediatric/adolescent brain tumours using individual-level data on solar exposures and key effect modifiers and potential confounders.
脑瘤是儿童癌症中第二常见的类型，也是儿童中最常见的实体瘤，但其病因在很大程度上是未知的。先前的一些研究表明，增加的紫外线辐射（UVR）暴露会降低脑肿瘤的风险，但证据并不一致。我们进行了一项横断面研究（使用人口普查得出的人口计数），使用地面uvr辐照度测量，通过准似然模型，通过年龄、性别、种族/民族和其他社会经济变量进行调整，评估年龄和20岁恶性/非恶性脑肿瘤的总体发病率，以及2000-2021年监测、流行病学和最终结果数据中的主要类别。恶性/非恶性脑肿瘤共有29,088/18,585例，两种肿瘤在UVR照射下的相对危险度(RR) = 0.754/mW/ cm2 （95% CI 0.659, 0.862, p < 0.0001）和非恶性脑肿瘤的相对危险度(RR = 0.466/mW/ cm2 （95% CI 0.382, 0.567, p < 0.0001）总体上呈显著下降趋势，但组织病理亚型、种族/民族和性别存在显著异质性。同样，在uvr累积辐射照射下，两种类型的肿瘤的发病率都有非常显著的下降趋势（p < 0.0001）。这些趋势在许多恶性/非恶性脑肿瘤组织病理学亚型和种族/民族群体中也很重要。然而，某些非恶性脑肿瘤亚型，例如松果体区肿瘤和脑膜肿瘤，其相对于UVR辐照度的RR显著超过1 （p = 0.0330, p = 0.0024）。我们的研究发现，紫外线辐射对脑肿瘤风险的一般保护作用尚不明确，需要对儿童/青少年特定组织病理学脑肿瘤进行大量研究，使用个人水平的太阳照射数据、关键效应调节剂和潜在混杂因素。
{"title":"Solar ultraviolet radiation exposure, and incidence of childhood (0–19 years) malignant and non-malignant brain tumour in a US population-based dataset, 2000–2021","authors":"Mark P. Little, Jim Z. Mai, Jill S. Barnholtz-Sloan, Martha S. Linet, Michelle Fang, Pavel Chernyavskiy, Victoria Kennerley, Elizabeth K. Cahoon, Myles G. Cockburn, Gerald M. Kendall, Michael G. Kimlin","doi":"10.1007/s10654-025-01314-w","DOIUrl":"https://doi.org/10.1007/s10654-025-01314-w","url":null,"abstract":"Brain tumour is the second most common type of childhood cancer and the most common solid tumour in children, but its aetiology is largely unknown. Some previous studies have suggested that elevated ultraviolet radiation (UVR) exposures decrease brain tumour risk, but the evidence is inconsistent. We conducted a cross-sectional study (with census-derived population counts) to assess age < 20 malignant/non-malignant brain tumour incidence overall and for major categories in Surveillance, Epidemiology and End Results 2000–2021 data, using ground-based UVR-irradiance measures, via quasi-likelihood models accounting for over/under-dispersion, adjusted for age, sex, race/ethnicity and other socioeconomic variables. There were 29,088/18,585 cases of malignant/non-malignant brain tumour, with generally significant decreasing trends of both types of tumour with UVR irradiance [relative risk (RR) = 0.754/mW/cm <jats:sup>2</jats:sup> (95% CI 0.659, 0.862, <jats:italic>p</jats:italic> < 0.0001) for malignant brain tumour, RR = 0.466/mW/cm <jats:sup>2</jats:sup> (95% CI 0.382, 0.567, <jats:italic>p</jats:italic> < 0.0001] for non-malignant brain tumour), although there was significant heterogeneity by histopathologic subtype, race/ethnicity, and sex. Equally, there is a highly significant decreasing trend of both types of tumour with UVR-cumulative radiant exposure ( <jats:italic>p</jats:italic> < 0.0001). These trends are also significant in many malignant/non-malignant brain tumour histopathological subtypes and racial/ethnic groups. However, there are certain non-malignant brain tumour subtypes, for example tumours of the pineal region and meningeal tumours, where RR significantly exceed 1 in relation to UVR irradiance ( <jats:italic>p</jats:italic> = 0.0330, <jats:italic>p</jats:italic> = 0.0024 respectively). Our finding, of a generally protective effect of UVR on brain tumour risk is not clear-cut, and warrants large studies of specific histopathological pediatric/adolescent brain tumours using individual-level data on solar exposures and key effect modifiers and potential confounders.","PeriodicalId":11907,"journal":{"name":"European Journal of Epidemiology","volume":"153 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145583354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-24DOI: 10.1007/s10654-025-01326-6
Emelie Rietz Liljedahl, Kari Nielsen, Malin Engfeldt, Anna Saxne Jöud, Christel Nielsen
The incidence of cutaneous melanoma (CM) has risen sharply over the past 30 years, coinciding with the rapidly growing tattoo trend. In Sweden, 20% of the population is tattooed. Repeated reports of the presence of carcinogenic chemicals, such as polyaromatic hydrocarbons, aromatic amines and heavy metals in tattoo ink justifies the investigation of CM risk in relation to tattooing. We aimed to investigate the potential association between tattoo exposure and CM. We identified 2880 individuals who were diagnosed with CM at age 20–60 years, in the Swedish National Cancer Register. For each case, we sampled three random age- and sex-matched controls from the Swedish Total Population Register. Exposure data and data on potential confounders were collected through a questionnaire in 2021. We estimated the relative risk of CM in tattooed compared with nontattooed individuals using multivariable logistic regression, rendering incidence rate ratios (IRR). Of the participants, 22% of the cases (354/1598) had a tattoo before the index date, vs. 20% of the controls (815/4097). We observed an adjusted relative risk of CM in tattooed compared to nontattooed individuals of 1.29 (95% confidence interval [CI]: 1.07–1.56). The results suggested that tattoos may be a risk factor for CM, but further studies are needed to establish causality.
{"title":"Does tattoo exposure increase the risk of cutaneous melanoma? A population-based case-control study","authors":"Emelie Rietz Liljedahl, Kari Nielsen, Malin Engfeldt, Anna Saxne Jöud, Christel Nielsen","doi":"10.1007/s10654-025-01326-6","DOIUrl":"https://doi.org/10.1007/s10654-025-01326-6","url":null,"abstract":"The incidence of cutaneous melanoma (CM) has risen sharply over the past 30 years, coinciding with the rapidly growing tattoo trend. In Sweden, 20% of the population is tattooed. Repeated reports of the presence of carcinogenic chemicals, such as polyaromatic hydrocarbons, aromatic amines and heavy metals in tattoo ink justifies the investigation of CM risk in relation to tattooing. We aimed to investigate the potential association between tattoo exposure and CM. We identified 2880 individuals who were diagnosed with CM at age 20–60 years, in the Swedish National Cancer Register. For each case, we sampled three random age- and sex-matched controls from the Swedish Total Population Register. Exposure data and data on potential confounders were collected through a questionnaire in 2021. We estimated the relative risk of CM in tattooed compared with nontattooed individuals using multivariable logistic regression, rendering incidence rate ratios (IRR). Of the participants, 22% of the cases (354/1598) had a tattoo before the index date, vs. 20% of the controls (815/4097). We observed an adjusted relative risk of CM in tattooed compared to nontattooed individuals of 1.29 (95% confidence interval [CI]: 1.07–1.56). The results suggested that tattoos may be a risk factor for CM, but further studies are needed to establish causality.","PeriodicalId":11907,"journal":{"name":"European Journal of Epidemiology","volume":"164 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145583184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-21DOI: 10.1007/s10654-025-01332-8
Whitney Wells,M Maria Glymour
{"title":"Individualizing social determinants of health: is educational attainment a community resource?","authors":"Whitney Wells,M Maria Glymour","doi":"10.1007/s10654-025-01332-8","DOIUrl":"https://doi.org/10.1007/s10654-025-01332-8","url":null,"abstract":"","PeriodicalId":11907,"journal":{"name":"European Journal of Epidemiology","volume":"79 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145559114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-12DOI: 10.1007/s10654-025-01303-z
Ulrike Haug,Mingyang Song,Vanessa Didelez
{"title":"No \"prevalence bias\" in randomized controlled trials on colorectal cancer screening: the importance of clarifying the research question.","authors":"Ulrike Haug,Mingyang Song,Vanessa Didelez","doi":"10.1007/s10654-025-01303-z","DOIUrl":"https://doi.org/10.1007/s10654-025-01303-z","url":null,"abstract":"","PeriodicalId":11907,"journal":{"name":"European Journal of Epidemiology","volume":"54 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145491464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-08DOI: 10.1007/s10654-025-01319-5
Hermann Brenner, Thomas Heisser, Michael Hoffmeister
{"title":"Overcoming prevalence bias in colorectal cancer screening studies by sensible analyses rather than ignoring it or giving up relevant effect measures","authors":"Hermann Brenner, Thomas Heisser, Michael Hoffmeister","doi":"10.1007/s10654-025-01319-5","DOIUrl":"https://doi.org/10.1007/s10654-025-01319-5","url":null,"abstract":"","PeriodicalId":11907,"journal":{"name":"European Journal of Epidemiology","volume":"92 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2025-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145461335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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