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2015 8th International Conference on Biomedical Engineering and Informatics (BMEI)最新文献

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Test of label-free Nasopharyngeal carinoma tissue at different stages by Raman spectroscopy 拉曼光谱法检测不同阶段无标记鼻咽癌组织
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401505
Mingyu Liu, S. Qiu, Jinyong Lin, Weilin Wu, Guannan Chen, Rong Chen
Raman spectroscopy (RS) of Nasopharyngeal carcinoma (NPC) tissue contained various biomedicine features. These features indicated molecular-level information of tissue at different carcinoma development-level. This study suggested an automatic and quick method for the NPC Raman spectra classification at different stages by multivariate statistical analysis. In the RS measurement, high quality Raman spectra was acquired from each NPC tissue sample in two groups: one group consisted of 30 NPC patients at the early stages (I-II), another group was 46 NPC patients at the advanced stages (III-IV). Moreover, tentative diagnostic algorithms based on principle components analysis (PCA) and support vector machine (SVM) were employed to classify the multivariate data of Raman spectra effectively. The classification performance (sensitivities and specificities were 70% (21/30) and 91% (42/46)) was achieved by the PCA-SVM in conjunction with leave-one-out cross validation method. In this beneficial study, the RS technique in conjunction with PCA-SVM provided a great clinical potential for rapid NPC stage diagnosis.
鼻咽癌组织的拉曼光谱(RS)具有多种生物医学特征。这些特征提示了不同肿瘤发展水平组织的分子水平信息。本研究提出了一种基于多元统计分析的不同阶段NPC拉曼光谱自动快速分类方法。RS测量中,从两组鼻咽癌组织样本中获得高质量的拉曼光谱:一组包括30例早期(I-II)鼻咽癌患者,另一组包括46例晚期(III-IV)鼻咽癌患者。此外,采用基于主成分分析(PCA)和支持向量机(SVM)的初步诊断算法对拉曼光谱的多变量数据进行有效分类。PCA-SVM结合留一交叉验证方法的分类性能达到了70%(21/30)和91%(42/46)。在这项有益的研究中,RS技术结合PCA-SVM为快速鼻咽癌分期诊断提供了巨大的临床潜力。
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引用次数: 0
Asymptotical stability for a class of discrete systems with variable delay 一类变时滞离散系统的渐近稳定性
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401568
Xinge Liu, Fengxian Wang, Meilan Tang, Yanjun Shu
In this paper, based on the discrete Wirtinger inequality, the problem of summation inequality is investigated. Some new summation inequalities are established, which extend the discrete Jensen inequality effectively. As an application of the summation inequalities, a novel sufficient criterion on asymptotical stability of discrete systems with variable delay is proposed. A numerical example is provided to show that our stability criterion achieves the improvements over the existing ones.
本文在离散Wirtinger不等式的基础上,研究了求和不等式的问题。建立了一些新的和不等式,有效地推广了离散Jensen不等式。作为求和不等式的一种应用,给出了变时滞离散系统渐近稳定性的一个新的充分判据。数值算例表明,本文提出的稳定性判据比已有的判据有了改进。
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引用次数: 1
Optimization of coils in wireless telemetry systems using the Particle Swarm Optimization algorithm 基于粒子群优化算法的无线遥测系统线圈优化
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401540
Xiyan Li, Miaorong Wang, Guoxing Wang
In this work, we propose to use the Particle Swarm Optimization (PSO) method to optimize the power efficiency, the data gain, and the interference of wireless telemetry systems. Two design cases are discussed. The first one is a power only transmission system which is used in retinal stimulation. The system's power transmission efficiency after proposed optimization can achieve 79.1% at the frequency of 1MHz. The real system is implemented in PCB, and the testing result is close to the simulations. We also compare the results obtained from the sweeping optimization method with the proposed PSO method for this design case. The second system is a dual band system which transmits power and data at the frequency of 1MHz and 13.56MHz separately. After optimization, the efficiency can achieve 74.8%, with a 5.137 data gain and a small interference of 0.055.
在这项工作中,我们提出使用粒子群优化(PSO)方法来优化无线遥测系统的功率效率、数据增益和干扰。讨论了两个设计案例。第一个是电力传输系统,用于视网膜刺激。优化后的系统功率传输效率在1MHz频率下可达到79.1%。实际系统在PCB上实现,测试结果与仿真结果接近。针对该设计实例,将扫描优化方法与粒子群优化方法的结果进行了比较。第二个系统是双频系统,分别以1MHz和13.56MHz的频率传输功率和数据。优化后的效率可达74.8%,数据增益5.137,干扰0.055。
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引用次数: 0
Bleeding fragment localization using time domain information for WCE videos 基于时域信息的WCE视频出血片段定位
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401476
Wei Shi, Junzhou Chen, Honghan Chen, Qiang Peng, Tao Gan
Small intestine bleeding is one of the most common disease in human gastrointestinal tract. The Wireless Capsule Endoscopy (WCE) has been an advanced technology to inspect the intestine in recent years. In this paper, a new time domain based method was proposed to locate bleeding fragment in WCE videos. The spatial feature and the time domain information were combined to make the decision. The proposed method consists of four phases: First, dark holes and wrinkle edges of each frame were removed in preprocessing. Second, each frame was segmented into small patches by using super-pixel segmentation. A coarse bleeding region filter was adopted to remove noisy patches. Third, the red ratio feature and the a feature of the WCE images were extracted. Finally, the bleeding fragment was detected based on the temporal red ratio feature and the temporal a features fusion. Experimental results show that the proposed method achieves good performance.
小肠出血是人类消化道最常见的疾病之一。无线胶囊内窥镜(WCE)是近年来小肠检查的一种先进技术。本文提出了一种新的基于时域的WCE视频出血片段定位方法。结合空间特征和时域信息进行决策。该方法分为四个阶段:首先,在预处理中去除每帧图像的黑洞和褶皱边缘;其次,利用超像素分割技术将每帧图像分割成小块;采用粗出血区滤波去除噪声斑块。第三,提取WCE图像的红比特征和a特征;最后,基于颞红比特征和颞a特征融合检测出出血碎片。实验结果表明,该方法具有良好的性能。
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引用次数: 3
Unsupervised segmentation for multiple sclerosis lesions in multimodality Magnetic Resonance images 多模态磁共振图像中多发性硬化症病变的无监督分割
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401486
Ziming Zeng, Siping Chen, Lidong Yin, R. Zwiggelaar
In this paper, a new unsupervised approach is proposed for the segmentation of Multiple Sclerosis (MS) lesions in multimodality Magnetic Resonance (MR) images. The proposed segmentation scheme is based on joint histogram modelling followed by false positive reduction and alpha matting, which is used to deal with the tissue density overlap problem and partial volume effects in MR images. Firstly, the joint histogram is generated by using fluid-attenuated inversion recovery (Flair), T1-weighted (T1-w) and T2-weighted (T2-w) MRI. Then the region for MS lesions in the joint histogram are located. Sub-sequently, the located region is projected back into the 2D MR images with potential MS lesions. Secondly, priori information is utilized to remove false positive volume of interests. Finally, the partial volume effect is modelled by using an alpha technique provides region level lesion refinement. Validation is performed on real multi-channel T1-w, T2-w, and Flair MR volumes. The experimental results show the proposed method can obtain better results than some state-of-the-art methods.
本文提出了一种新的多模态磁共振(MR)图像中多发性硬化症(MS)病灶的无监督分割方法。提出的分割方案基于联合直方图建模,然后是假阳性还原和α抠图,用于处理MR图像中的组织密度重叠问题和部分体积效应。首先,利用流体衰减反演恢复(Flair)、t1加权(T1-w)和t2加权(T2-w) MRI生成关节直方图。然后定位关节直方图中MS病变的区域。随后,将定位的区域投影回具有潜在MS病变的2D MR图像。其次,利用先验信息去除假阳性兴趣量。最后,使用alpha技术对部分体积效应进行建模,从而提供区域级病变细化。验证在真实的多通道T1-w, T2-w和Flair MR卷上执行。实验结果表明,该方法比现有的一些方法能获得更好的结果。
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引用次数: 3
An improved hybrid algorithm for traveling salesman problem 旅行商问题的一种改进混合算法
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401613
Qiuying Bai, Guizhi Li, Qiheng Sun
An improved artificial bee colony (ABC&VNS) to settle the traveling salesman problem (TSP) is described in this paper. This hybrid algorithm's principal character is to incorporate the solution construction mechanism of the artificial bee colony (ABC) with variable neighborhood search (VNS) to exploit the intrinsic structure of the solutions to acquire the high quality solution. Besides, three novel neighborhood structures are present, in which problem-specific knowledge is utilized respectively, to improve both the search efficiency and quality of VNS. Finally, the experiments for benchmark TSP instances are carried out to verify that the proposed algorithm is capable of maintaining high performance to solve the TSP, which is compared with the best existing approaches in the way of solution quality.
提出了一种求解旅行商问题的改进人工蜂群算法(ABC&VNS)。该混合算法的主要特点是将人工蜂群(ABC)的解构造机制与变邻域搜索(VNS)相结合,利用解的内在结构获得高质量的解。此外,本文还提出了三种新的邻域结构,分别利用了问题相关知识,提高了VNS的搜索效率和质量。最后,对基准TSP实例进行了实验,验证了所提算法在求解TSP时能够保持较高的性能,并在求解质量方面与现有最佳方法进行了比较。
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引用次数: 2
A novel hybrid rendering approach to soft tissue cutting in surgical simulation 一种新的手术模拟中软组织切割的混合渲染方法
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401514
Jie Luo, Shaoping Xu, Shunliang Jiang
As a feasible alternative approach, computer-based surgical simulators have been developed over the past few decades to enhance traditional surgical training. But most surgery simulators still suffer from stability and efficiency problems when simulating complex surgical procedures like cutting with respect to the graphical rendering. For naturalistic rendering, the response of soft tissue during the cutting operation should be cautiously verified, analyzed and simulated. In this paper, a novel hybrid rendering approach to tracheotomy simulation combining traditional mesh-based rendering with emerging point-based rendering is proposed, where mesh-based rendering algorithm is applied on the non-surgical area while point-based rendering algorithm is applied on the surgical area. Central to our method is different appropriate rendering methods applied to the two regions respectively, resulting in a contribution to the speed up of the calculation. The approach has been integrated into our virtual tracheotomy surgery training prototype system. The details and results of experiments indicate that our hybrid rendering approach is suitable in the design of surgical simulators. It can keep the visual reality while significantly increasing the efficiency and stability for simulation of soft-tissue's cutting.
作为一种可行的替代方法,在过去的几十年里,基于计算机的手术模拟器已经发展起来,以增强传统的外科训练。但是,大多数手术模拟器在模拟复杂的外科手术过程(如切割)时,在图形渲染方面仍然存在稳定性和效率问题。为了更自然地呈现,应仔细验证、分析和模拟切割过程中软组织的响应。本文提出了一种将传统的基于网格的渲染与新兴的基于点的渲染相结合的新型气管切开术模拟混合渲染方法,其中非手术区域采用基于网格的渲染算法,手术区域采用基于点的渲染算法。我们方法的核心是分别对两个区域应用不同的适当呈现方法,从而有助于提高计算速度。该方法已集成到我们的虚拟气管切开术训练原型系统中。实验的细节和结果表明,我们的混合渲染方法适用于手术模拟器的设计。在保持视觉真实性的同时,显著提高了模拟软组织切割的效率和稳定性。
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引用次数: 1
An innocuous spine structure analysis method based on surface asymmetry evaluation 基于表面不对称评价的脊柱无害结构分析方法
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401492
Chi Zhang, Xiaomin Liu, Wei Guo, Han-ping Wang, Zihao Li
Spine morphological analysis plays an important role in various medical purposes. However, the most conventional methods for the task employing radiography techniques cause considerable radiation damage to the patient and costs such high expense, which is not suitable for frequent examinations and treatments for certain groups of patient. Depending on the subjective analysis is also an obvious shortcoming of the methods. In this paper, we developed an innocuous spine morphological analysis method based on the surface asymmetry information of the patient's back, which causes no damage to the patient and provides a satisfying efficiency and low cost.
脊柱形态学分析在各种医学用途中起着重要的作用。然而,传统的放射成像技术对患者造成相当大的辐射损伤,且费用高昂,不适合对某些患者群体进行频繁的检查和治疗。依赖主观分析也是该方法的一个明显缺点。本文提出了一种基于患者背部表面不对称信息的无害化脊柱形态分析方法,该方法对患者无损伤,且具有令人满意的效率和低成本。
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引用次数: 1
Security system construction of land and resources network based on intrusion detection 基于入侵检测的国土资源网络安全系统构建
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401611
C. Shen, Zhongyang Chen, Yu Xue
Intrusion detection can decide whether there are dangerous user behaviors. It can also timely detect network security vulnerabilities of inner attacks, and it can make quick response and improve network security. Therefore, it is necessary to research about the intrusion detection in land and resources information systems. For the security status of land and resources network, we place the security architecture platform and select different types of attacks to test the systems. The test results verify the stability, reliability and scalability of the systems, achieving the needed results.
入侵检测可以判断是否存在危险的用户行为。它还可以及时发现内部攻击的网络安全漏洞,并可以快速响应,提高网络安全性。因此,有必要对国土资源信息系统中的入侵检测进行研究。针对国土资源网络的安全现状,搭建了安全架构平台,并选择了不同类型的攻击对系统进行了测试。测试结果验证了系统的稳定性、可靠性和可扩展性,达到了预期的效果。
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引用次数: 0
A prototype of healthcare big data processing system based on Spark 基于Spark的医疗大数据处理系统原型
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401559
Wenzhi Liu, Qi Li, Yunpeng Cai, Ye Li, Xiaoyan Li
With many theoretical and technological obstacles in health big data processing, it is hard to transfer data into successful and valuable applications. Meeting the Challenge of handling big data in healthcare information construction procedure, this paper proposes a referential architecture on the platform solution to overcome the problems in tremendous of healthcare big data process. Based on the proposed architecture a prototype has been built for healthcare big data analysis. Taking statistical analysis in administrator decide supporting service as an example, this paper tests the running performance and demonstrating effect of the prototype system for healthcare big data processing based on Spark.
健康大数据处理存在诸多理论和技术障碍,难以将数据转化为成功的、有价值的应用。针对医疗信息化建设过程中大数据处理的挑战,本文提出了一种基于平台的参考架构解决方案,以克服医疗大数据处理过程中存在的巨大问题。基于所提出的架构,构建了用于医疗保健大数据分析的原型。本文以管理员决策支持服务中的统计分析为例,对基于Spark的医疗大数据处理原型系统的运行性能和演示效果进行了测试。
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引用次数: 13
期刊
2015 8th International Conference on Biomedical Engineering and Informatics (BMEI)
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