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2015 8th International Conference on Biomedical Engineering and Informatics (BMEI)最新文献

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A positive region-based dimensionality reduction from high dimensional data 一种基于区域的高维数据降维方法
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401579
Dai Zhe, L. Jianhui
Dimensionality reduction is an important attribute process work. Dimensionality reduction, i.e, attribute reduction is to delete some uncesserary attributes at rough sets. At present, many attribute reduction methods have provided to delete some superfluous and irrelevant attributes from large-scale complete data sets. The main drawback of most attribute reduction algorithms is that they can not remove some examples in the process of dimensionality reduction, which degrades a computational efficiency of attribute reduction. To overcome this drawback, an improved attribute reduction algorithm for complete data sets is proposed. In addition, the classification performance of attribute reduction is optimized. At first, the compact decision system is presented to delete some repeated objects. Then the significance measure of attributes is provided for candidate attributes. In addition, the novel approach of attribute reduction under the proposed significance measure of attributes was developed. In order to verify the efficiency of our given algorithm, the experiments on UCI datasets are performed by comparing with other attribute reduction algorithms. The results on the experiments tell us that our given algorithm obtains promising improvement for selecting an attribute reduct.
降维是一项重要的属性处理工作。降维即属性约简就是在粗糙集上删除一些不需要的属性。目前,已有许多属性约简方法用于从大规模完整数据集中删除一些多余和不相关的属性。大多数属性约简算法的主要缺点是不能在降维过程中去除一些样本,从而降低了属性约简的计算效率。为了克服这一缺点,提出了一种改进的完整数据集属性约简算法。此外,对属性约简的分类性能进行了优化。首先,提出了一种精简决策系统,用于删除一些重复对象。然后给出了候选属性的显著性度量。在此基础上,提出了一种新的属性显著性度量下的属性约简方法。为了验证本文算法的有效性,通过与其他属性约简算法的对比,在UCI数据集上进行了实验。实验结果表明,该算法在选择属性约简方面取得了很好的改进。
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引用次数: 0
A liquid conductivity measurement system based on electromagnetic induction 一种基于电磁感应的液体电导率测量系统
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401603
Jing Liu, Li Ke, Qiang Du, Ling Han
Electromagnetic measurement method was a non-contact biological tissue conductivity measurement technology. This paper presented a liquid conductivity measurement system based on electromagnetic induction; phase difference information of induced magnetic field was used as detection signal in the system. Firstly, the system was composed of excitation source based on directly digital synthesis, phase detector based on SR844 RF lock-in amplifier, excitation-detection coils sensor and signal processing circuit. Secondly, the maximum error of exciting source frequency accuracy was 2.4%, the phase drift of system was 0.001° /min, the phase resolution was 0.02°, the minimum conductivity could be detected by this system was 0.004S/m. Finally, the saline solution experiments of different concentration and different kinds of drinking water were made by this system, the experimental results demonstrated that the system could obviously identify category of water, and measurement results were consistent with the theory of electromagnetic field.
电磁测量法是一种非接触式生物组织电导率测量技术。提出了一种基于电磁感应的液体电导率测量系统;系统采用感应磁场的相位差信息作为检测信号。首先,系统由基于直接数字合成的激励源、基于SR844射频锁相放大器的鉴相器、激励检测线圈传感器和信号处理电路组成。其次,激励源频率精度的最大误差为2.4%,系统相漂移为0.001°/min,相分辨率为0.02°,系统可检测的最小电导率为0.004S/m。最后,利用该系统对不同浓度的盐水溶液和不同种类的饮用水进行了实验,实验结果表明,该系统能明显识别水的种类,测量结果与电磁场理论相吻合。
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引用次数: 0
A comparison of the Homodyned K-distribution and the single distributions for RF ultrasonic speckle modeling 射频超声散斑建模中homodyk分布与单一分布的比较
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401487
Xiao Hu, Yufeng Zhang, Li Deng, Shuang Peng, Kexin Zhang
For observing the parameters and the fitting performance, this paper compares the Homodyned K-distribution with the single distributions for RF ultrasonic speckle modeling. To implement different scatterer distributions representing a variable density of random scatterers with or without coherent component, A set of 3D scatterer models are built based on a three-dimensional Hilbert curve following Gamma distributions with different values of shape and scale parameters. The RF data are simulated by using the Field II software. Then the maximum likelihood estimation (MLE) for statistical histograms of the energy of the RF data is performed to obtain the values of log-likelihood and model parameters. In order to evaluate the fitting performance and parameter meaning of the HK distribution, the mean and standard deviation of these estimated values are compared with those based on the optimal fitting model chosen from commonly used single-distributions (OSD), the K, Rayleigh and Rician distributions. The results show the parameters of Homodyned K-distribution obtained by the MLE could independently represent the clustered, random or uniform characteristics for scatterer distribution. However, the fitting accuracy could only catch up with that based on the OSD joint model under the condition that the tissue contains the scatterers from medium to high effective-density, as well as deterministic or non-deterministic components. The OSD model is still a better choice in the case of the fitting performance emphasized in practice, especially the tissue with a wider range of scatterer densities and deterministic components.
为了观察参数和拟合性能,本文将高频超声散斑建模的homodyk分布与单一分布进行了比较。为了实现具有或不具有相干分量的可变密度随机散射体的不同散射体分布,基于遵循不同形状和尺度参数值的Gamma分布的三维Hilbert曲线,建立了一组三维散射体模型。利用Field II软件对射频数据进行仿真。然后对射频数据的能量统计直方图进行最大似然估计(MLE),得到对数似然值和模型参数。为了评价HK分布的拟合性能和参数意义,将这些估估值的均值和标准差与基于常用单分布(OSD)、K分布、Rayleigh分布和rics分布中选择的最优拟合模型的均值和标准差进行比较。结果表明,MLE得到的Homodyned k分布参数可以独立地表示散点分布的聚类、随机或均匀特征。然而,只有在组织中含有中高有效密度的散射体,以及确定性或非确定性成分的情况下,拟合精度才能赶上基于OSD关节模型的拟合精度。在实践中强调拟合性能的情况下,特别是在散射体密度范围较大、成分具有确定性的组织中,OSD模型仍然是较好的选择。
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引用次数: 0
An optimizing procedure of the wireless power transfer link for an intraocular implantable device 一种眼内植入式装置无线电力传输链路的优化方法
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401526
Zhidong Miao, Dake Liu, Chen Gong
This paper presents a design method and results of prototyping for the wireless power transfer (WPT) link used in intraocular implantable devices. In this kind of applications, the coil size is constrained strictly, which makes it hard to find an efficient configuration by only changing the coil geometry. Therefore, in our design, we took frequency into account as another design dimension to expand the design margin. We set up a WPT design flow using a novel scope of matching network and taking frequency as a variable parameter. Finally, we obtained a WPT coupling efficiency up to 63.9%.
本文介绍了一种用于眼内植入式装置的无线电力传输链路的设计方法和原型设计结果。在这类应用中,线圈的尺寸受到严格的限制,这使得仅通过改变线圈的几何形状很难找到有效的配置。因此,在我们的设计中,我们将频率作为另一个设计维度来考虑,以扩大设计余量。以频率为可变参数,采用新颖的匹配网络范围,建立了WPT设计流程。最后,我们获得了高达63.9%的WPT耦合效率。
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引用次数: 3
The magnetic induction tomography measurement system based on Helmholtz coil 基于亥姆霍兹线圈的磁感应层析成像测量系统
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401468
Haijun Luo, Xin Jiang
Magnetic induction tomography (MIT) is a contactless measurement of biological tissue conductivity imaging technique. The spiral coil is widely used, which leads to the nonuniformity of sensitivity distribution of the detection signal. This paper proposed the Helmholtz coil which can generate a set of uniform excitation fields, and analyzed the uniformity of excitation field. In MIT system, the exciting magnetic field is generated through sine-wave current, with the frequency of 10MHz and exciting current of 20mA. The experimental physics model simulated cerebral hemorrhage is produced by using the distilled water, the agar powder and NaCl. The result experiments show that this system can test the changes of the conductivity of partial tissues, and reflect the position of the foreign matter, but the image is enlarged compared with the actual one.
磁感应层析成像(MIT)是一种非接触式测量生物组织电导率的成像技术。螺旋线圈的广泛使用导致了检测信号灵敏度分布的不均匀性。提出了一种能产生一组均匀激励场的亥姆霍兹线圈,并对其均匀性进行了分析。在MIT系统中,激励磁场是通过正弦波电流产生的,频率为10MHz,激励电流为20mA。采用蒸馏水、琼脂粉和NaCl制备了模拟脑出血的实验物理模型。实验结果表明,该系统可以检测局部组织的电导率变化,并反映异物的位置,但图像与实际相比有所放大。
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引用次数: 3
Predicting minimum inhibitory concentration of antimicrobial peptides by the pseudo-amino acid composition and Gaussian kernel regression 利用伪氨基酸组成和高斯核回归预测抗菌肽的最小抑菌浓度
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401519
Xuan Xiao, Zhi-Bing You
Antimicrobial peptides (AMPs), which is a kind of short chain protein, have a strong antimicrobial ability which have antibacterial, antifungal, antiviral effect. Over the last few decades, the research of AMPs is drawing in large scholars, many of whom have engaged in the profound study on predicting AMPs activity, particularly in the AMPs classification. According to microbiology, the minimum inhibitory concentration (MIC) is a kind of antibacterial agent, its concentration is the lowest, which can inhibit the growth of the microorganism. MIC is very crucial in diagnostic lab to prove that the microbial resistance to antimicrobial agents, and to monitor the activity of new antimicrobial agents. It is generally considered as a most basic laboratory for measuring the activity of resistance on living organisms. Due to the process of biological experiments are expensive and cost plenty time, it is the highest favorable and practicable to design an efficacious computer-based MIC prediction method. In this paper, an antimicrobial peptides MIC predictor called "MIC", in which peptides sequence were formulated by incorporating five physicochemical properties into pseudo amino acid composition (PseAAC) and Gaussian kernel regression. According to the result of the MIC showed that the result of the method and experimentally result is high consistent.
抗菌肽是一种短链蛋白,具有很强的抗菌能力,具有抗菌、抗真菌、抗病毒等作用。在过去的几十年里,amp的研究吸引了大量的学者,其中许多人对amp的活性预测,特别是amp的分类进行了深入的研究。根据微生物学,最低抑菌浓度(MIC)是一种抗菌剂,它的浓度最低,能抑制微生物的生长。MIC在诊断实验室证明微生物对抗菌药物的耐药性,以及监测新型抗菌药物的活性方面具有重要意义。它通常被认为是测量生物体耐药性活性的最基本的实验室。由于生物实验过程成本高,耗时长,设计一种有效的基于计算机的MIC预测方法是最有利和可行的。本文提出了一种抗菌肽MIC预测器“MIC”,通过将5种理化性质与伪氨基酸组成(PseAAC)结合高斯核回归,确定抗菌肽序列。根据MIC计算结果表明,该方法的计算结果与实验结果具有较高的一致性。
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引用次数: 2
The phasel-contrast CT imaging and X-ray fluorescence analysis of Zusanli acupuncture point (ST 36) based on synchrotron radiation 基于同步辐射的足三里穴(st36) CT相衬成像及x射线荧光分析
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401508
Cheng-Lin Liu, Xiaohua Wang, Xu Hua, Dongming Zhang, Xingyi Zhang
In this paper, the micro-structure of Zusanli acupuncture point was studied using synchrotron radiation-based phase contrast CT imaging (PCI-CT) method and X-ray fluorescence (XRF) analysis method. The micro-structures of the point were displayed through the topography and trace elements distributions. In this experiment, there are good results for PCI-CT method based on synchrotron radiation; the special resolution reached the dimension of micrometer. Compared to the images of the PCI-CT, which were taken at acupuncture points and non-acupuncture point areas, we find the micro vessels gather in the acupuncture points. In addition, the structures of acupuncture points are different from the surrounding tissues through XRF mapping method. The acupuncture points' structure is different from that of the non-acupuncture points. In the acupuncture point area there is some micro-vascular aggregation, which reveals the differences of the acupoints and non-acupoints. The content of trace elements at the acupuncture points are more than those in the surrounding tissues, which can be inferred that there were the accumulation of trace elements at the acupuncture points' area. The XRF mapping shows that the distributions of Ca, Fe, Cu and Zn elements were similar to their morphology. These differences demonstrate the existence of the acupuncture points. We hope that these results can provide a new basis for our scientific understanding of acupuncture points.
本文采用同步辐射相对比CT成像(PCI-CT)方法和x射线荧光(XRF)分析方法对足三里穴的微观结构进行了研究。通过形貌和微量元素的分布显示了点的微观结构。在本实验中,基于同步辐射的PCI-CT方法取得了较好的效果;特殊分辨率达到微米级。对比PCI-CT在穴位和非穴位区域的图像,我们发现微血管在穴位聚集。此外,通过XRF成像方法,穴位的结构与周围组织不同。穴位的结构不同于非穴位。穴位区有微血管聚集,揭示了穴位与非穴位的差异。穴位处的微量元素含量高于周围组织,可以推断穴位处存在微量元素的积累。XRF测图表明,Ca、Fe、Cu和Zn元素的分布与其形貌相似。这些差异证明了穴位的存在。我们希望这些结果能够为我们对穴位的科学认识提供新的依据。
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引用次数: 1
Target vessel identification in endoscopic coronary artery bypass grafting 内镜下冠状动脉旁路移植术中靶血管的识别
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401541
Yifeng Sun, Lixu Gu, Junfeng Cai
Minimal invasive direct coronary artery bypass grafting (MIDCAB) procedures are potentially advantageous over conventional open surgery, while one major limitation is the narrow view of the endoscope and the difficulty in detecting stenosis from the endoscopic view. In this paper, we propose a frame to align the endoscope view and the 3D-vessel model reconstructed from angiography. We register the endoscopic video frame with the 3D-vessel model by electro-magnetic sensor, and then we segment the vessel in the endoscopic video frame with HSV (hue, saturation, value) and hessian transformation, and refined the registration with the vessel model by Coherent Points Drifting. We have validated the proposed method on a static phantom heart model and a real patient's endoscope video. RMSE (root mean-square error) was employed to evaluate our method and the registration error for the phantom model were 1.1+-0.2mm, for the real patient was 3.1mm.
微创直接冠状动脉旁路移植术(MIDCAB)与传统的开放手术相比具有潜在的优势,但一个主要的限制是内窥镜视野狭窄,难以从内窥镜视野中发现狭窄。在本文中,我们提出了一种框架来对齐内窥镜视图和由血管造影重建的3d血管模型。首先利用电磁传感器将内镜视频帧与3d血管模型进行配准,然后利用HSV (hue, saturation, value)变换和hessian变换对内镜视频帧中的血管进行分割,最后利用相干点漂移(Coherent Points Drifting)对血管模型进行细化配准。我们已经在一个静态模拟心脏模型和一个真实病人的内窥镜视频上验证了所提出的方法。采用均方根误差(RMSE)对我们的方法进行评价,模型的配准误差为1.1±0.2mm,真实患者的配准误差为3.1mm。
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引用次数: 0
Frontal alpha asymmetry during the audio emotional experiment revealed by event-related spectral perturbation 事件相关谱扰动揭示的音频情绪实验中额叶α不对称性
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401562
Ruoyu Du, H. Lee
Due to the recent development of brain computer interfaces (BCI), there has been certain relationship between emotion and brain electrical activities. Brain asymmetry could be used for enhanced electroencephalogram (EEG)-based emotional recognition as a prominent feature. Prefrontal hemispheric asymmetries have been proposed in twenty years ago. It is measured by the power of EEG signal in alpha band (8-13Hz), which is related to electrical power response to different emotional stimuli. In this paper, we designed an auditory evoked emotional experiment in order to explore EEG frontal alpha asymmetry by comparing event-related spectral perturbation (ERSP) maps of left and right frontal regions. Thirty healthy male students are employed to stimulate emotion by affective sound clips. All of auditory evoked stimuli come from the standard International Affective Digitized Sounds (IADS) dataset. ERSP maps exhibited that there are the strongest responses of positive sounds overspread the frontal lobe. To be specific, the right prefrontal and whole medial frontal EEG activation are elicited the stronger responses by emotional sounds of high pleasure-arousal, whereas the left prefrontal and whole medial frontal EEG activation are elicited the stronger responses by emotional sounds of middle pleasure-low arousal. Additionally, the stronger responses of high-arousal level sound clips have been found out over the whole right frontal region, while the low-arousal level sound clips can elicit greater relative electrical power over the whole left frontal region.
由于近年来脑机接口(BCI)的发展,情绪与脑电活动之间存在一定的关系。脑不对称可以作为一个显著特征用于增强的基于脑电图(EEG)的情绪识别。前额叶半球不对称在20年前被提出。脑电信号在α波段(8-13Hz)的功率测量,与不同情绪刺激下的电功率反应有关。本文设计了一个听觉诱发情绪实验,通过比较左、右额叶区域的事件相关谱摄动(ERSP)图,探讨脑电额叶α的不对称性。本研究以30名健康男生为研究对象,通过情感性的声音片段来刺激他们的情绪。所有的听觉诱发刺激来自标准的国际情感数字化声音(IADS)数据集。ERSP图显示,正面声音的最强反应遍布前额叶。其中,高愉悦性唤醒的情绪声音诱发右侧前额叶和整个内侧额叶的脑电激活较强,而中愉悦性唤醒的情绪声音诱发左侧前额叶和整个内侧额叶的脑电激活较强。此外,高唤醒水平的声音片段在整个右额叶区域产生更强的反应,而低唤醒水平的声音片段在整个左额叶区域产生更大的相对电功率。
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引用次数: 6
Drowsiness estimation under driving environment by heart rate variability and/or breathing rate variability with logistic regression analysis 用心率变异性和/或呼吸变异性估计驾驶环境下的睡意,并结合逻辑回归分析
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401498
T. Igasaki, Kazuki Nagasawa, N. Murayama, Zhencheng Hu
It is widely known that many traffic accidents occur every year, not only in Japan but also in the world. Drowsiness or sleepiness, which is the cause of dozing at the wheel, happens regardless of the physical condition of the driver after having meals or during midnight. This means that to avoid driver's drowsiness or sleepiness by oneself is hard. Therefore, various systems have been proposed to prevent traffic accidents caused by dozing at the wheel. In this study, we examined the relationship between psychological drowsiness during driving, which was evaluated by the Japanese version of the Karolinska sleepiness scale (KSS-J) and physiological parameters extracted from electrocardiogram and respiration signals. Then we tried to estimate the existence of drowsiness using logistic regression analysis on that parameters. In this study, since KSS-J score 7 indicates sleepy, we determined KSS-J score 7 and more as drowsiness state. The logistic regression method was performed using the half of the data for each subject and used the remaining data as the testing data. As a result, we got 71% of accuracy with heart rate variability (HRV), 72% of accuracy with breathing rate variability (BRV), 81% of accuracy with both signals in the whole subjects using logistic regression. Therefore, it is suggested that HRV and BRV parameters are relevant to drowsiness.
众所周知,不仅在日本,而且在世界上每年都发生许多交通事故。在开车时打瞌睡的原因,无论司机的身体状况如何,在吃完饭后还是在半夜,都会出现困倦或困倦。这意味着避免司机困倦或自己困倦是很难的。因此,人们提出了各种各样的系统来防止因开车打瞌睡而引起的交通事故。本研究采用日本版卡罗林斯卡睡意量表(KSS-J)评估驾驶过程中的心理睡意,并从心电图和呼吸信号中提取生理参数。然后,我们试图使用逻辑回归分析对这些参数估计困倦的存在。在本研究中,由于KSS-J得分为7分表示困倦,因此我们将KSS-J得分为7分及以上定为困倦状态。采用logistic回归方法对每个受试者取一半数据,其余数据作为检验数据。结果,我们在所有受试者中使用逻辑回归得到心率变异性(HRV)的准确率为71%,呼吸频率变异性(BRV)的准确率为72%,两种信号的准确率为81%。因此,我们认为HRV和BRV参数与嗜睡有关。
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引用次数: 21
期刊
2015 8th International Conference on Biomedical Engineering and Informatics (BMEI)
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