Pub Date : 2024-10-01DOI: 10.1016/j.ejca.2024.114553
F. Putti, F. Zonca, M. Figini, E. Luison, F. De Santis, M. Di Nicola
{"title":"25 (PB013): Design, development and characterization of novel CAR T cells targeting globo-H for solid tumor cell therapy","authors":"F. Putti, F. Zonca, M. Figini, E. Luison, F. De Santis, M. Di Nicola","doi":"10.1016/j.ejca.2024.114553","DOIUrl":"10.1016/j.ejca.2024.114553","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"211 ","pages":"Article 114553"},"PeriodicalIF":7.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142534806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ejca.2024.114581
L. Graves, S. Daglish, O. Canterbury, A. Mistreanu, P. Graves, E. Iwanowicz
{"title":"54 (PB042): The Application of Small Molecule ClpP Agonists as Novel Anti-Cancer Agents","authors":"L. Graves, S. Daglish, O. Canterbury, A. Mistreanu, P. Graves, E. Iwanowicz","doi":"10.1016/j.ejca.2024.114581","DOIUrl":"10.1016/j.ejca.2024.114581","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"211 ","pages":"Article 114581"},"PeriodicalIF":7.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142534388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ejca.2024.114537
T. Wang, M. Ibanez, K. Yu, K. Fan, J. Juan, M. Perez, T. Smith, B. Walsh, V. Kang, J. Tyhonas, N. Alvarez, J. Tran, K.S. Moorefield, A. Phimister, X. Zhu, A. Chi, M.D. Bartberger, E. Murphy
{"title":"8 Oral: ALTA3263: an oral, KRAS isoform-selective, dual ON/OFF state, noncovalent inhibitor induces regressions across KRAS G12V, G12D, and G12C cancer models","authors":"T. Wang, M. Ibanez, K. Yu, K. Fan, J. Juan, M. Perez, T. Smith, B. Walsh, V. Kang, J. Tyhonas, N. Alvarez, J. Tran, K.S. Moorefield, A. Phimister, X. Zhu, A. Chi, M.D. Bartberger, E. Murphy","doi":"10.1016/j.ejca.2024.114537","DOIUrl":"10.1016/j.ejca.2024.114537","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"211 ","pages":"Article 114537"},"PeriodicalIF":7.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142534546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ejca.2024.114624
A. Tedeschi, D.H. Peng, F. Schischlik-Siegl, O. Schaaf, D. Gerlach, F. Rocchetti, J. Popow, J. Broeker, T. Wunberg, A.S. Boghossian, M.G. Rees, M.M. Ronan, J.A. Roth, M. Williams, C. Vellano, J.R. Marszalek, T.P. Heffernan, M. Pearson, N. Kraut, R. Dorothea
{"title":"100 (PB088): KRASmulti inhibitor BI 3706674 shows efficacy in KRAS-driven preclinical models of cancer that supports clinical testing in patients with tumors harboring KRASG12V mutations and KRAS wild-type amplifications.","authors":"A. Tedeschi, D.H. Peng, F. Schischlik-Siegl, O. Schaaf, D. Gerlach, F. Rocchetti, J. Popow, J. Broeker, T. Wunberg, A.S. Boghossian, M.G. Rees, M.M. Ronan, J.A. Roth, M. Williams, C. Vellano, J.R. Marszalek, T.P. Heffernan, M. Pearson, N. Kraut, R. Dorothea","doi":"10.1016/j.ejca.2024.114624","DOIUrl":"10.1016/j.ejca.2024.114624","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"211 ","pages":"Article 114624"},"PeriodicalIF":7.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142526355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ejca.2024.115026
{"title":"Peer Review Policy for the European Journal of Cancer (EJC)","authors":"","doi":"10.1016/j.ejca.2024.115026","DOIUrl":"10.1016/j.ejca.2024.115026","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"211 ","pages":"Article 115026"},"PeriodicalIF":7.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142534666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ejca.2024.114619
K. Serala, S. Mdletshe, J. Bai, A. Abrahams, S. Prince
{"title":"93 (PB081): The T-BOX transcription factors TBX2 and TBX3 are molecular targets of piroctone olamine in the treatment of pancreatic ductal adenocarcinoma","authors":"K. Serala, S. Mdletshe, J. Bai, A. Abrahams, S. Prince","doi":"10.1016/j.ejca.2024.114619","DOIUrl":"10.1016/j.ejca.2024.114619","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"211 ","pages":"Article 114619"},"PeriodicalIF":7.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142534681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ejca.2024.114566
C. Chen, M. Xu, X. Lv, Y. Hu, L. Zhao, X. Chen, Y. Chen, C. Yang, J. Li
{"title":"38 (PB026): The novel dual MEK inhibitor ABM-4095 for RAS-mutated lung cancer as a single agent or in combination with known therapies","authors":"C. Chen, M. Xu, X. Lv, Y. Hu, L. Zhao, X. Chen, Y. Chen, C. Yang, J. Li","doi":"10.1016/j.ejca.2024.114566","DOIUrl":"10.1016/j.ejca.2024.114566","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"211 ","pages":"Article 114566"},"PeriodicalIF":7.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142533846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}