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Induction and Augmentation of Labor 引产和助产
Pub Date : 2019-02-12 DOI: 10.2310/obg.19023
C. Morosky
Certain maternal and fetal conditions require induction of labor for the safety and well-being of either the mother or baby. Similarly, once fetal maturity has been reached, elective induction of labor remains an option for delivery timing and patient request. A thorough understanding of the physiologic mechanisms of labor onset and maintenance has allowed obstetrical providers to induce labor from the quiescent state and augment spontaneous labor in the latent or prolonged state. The goal of labor induction and augmentation is the successful and expedited delivery of the neonate in a manner that is safe to both the mother and the infant. Positive maternal outcomes include a shortened admission to onset of labor time, shortened first stage of labor, successful vaginal delivery, and avoidance of intraamniotic infection or postpartum hemorrhage. Positive fetal outcomes include absence of meconium amniotic fluid staining, regular newborn nursery admission, and hospital discharge with the mother. In this review, we outline the various mechanical, chemical, and natural methods of labor induction and augmentation, including a detailed assessment of the risks and benefits of each method for both the mother and baby.This review contains 7 figures, 4 tables, and 33 references.Key Words: amniotomy, augmentation of labor, cervical ripening, induction of labor, oxytocin, membrane sweeping, nipple stimulation, prostaglandins, transcervical balloon catheter
为了母亲或婴儿的安全和健康,某些产妇和胎儿的情况需要引产。同样,一旦胎儿成熟,选择性引产仍然是分娩时间和患者要求的一种选择。对分娩发生和维持的生理机制的全面了解,使产科医生能够从静止状态诱导分娩,并在潜伏或延长状态下增加自然分娩。引产和助产的目的是以对母亲和婴儿都安全的方式成功和迅速地分娩新生儿。积极的产妇结局包括缩短入院开始分娩时间,缩短第一产程,阴道分娩成功,避免羊膜内感染或产后出血。阳性胎儿结局包括无胎粪羊水染色,新生儿常规托儿所住院,随母亲出院。在这篇综述中,我们概述了各种机械、化学和自然的引产和增强方法,包括对每种方法对母亲和婴儿的风险和益处的详细评估。本综述包含7张图,4张表,33篇参考文献。关键词:羊膜切开,催产,宫颈成熟,引产,催产素,扫膜,乳头刺激,前列腺素,经宫颈球囊导管
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引用次数: 0
Peripartum Cardiomyopathy
Pub Date : 2018-11-20 DOI: 10.2310/obg.19065
K. Gray, M. Foley
Peripartum cardiomyopathy (PPCM) is a serious and rare disease of late pregnancy or the early postpartum period. It is defined as idiopathic, nonfamilial, nongenetic, heart failure occurring in the absence of any other identifiable causes of heart disease within the last month of pregnancy or within the first 5 months postdelivery in otherwise previously healthy woman. The incidence in the United States is 1 per 3,000 to 4,000 live births. Left ventricular systolic dysfunction develops, almost always leading to a left ventricular ejection fraction of less than 45%. PPCM is unique in its rapid medical course and propensity to spontaneously resolve within 3 to 6 months of disease onset. The mortality rate is high, up to 10%, and the risk of relapse in subsequent pregnancies is also elevated. Treatment for PPCM varies slightly based on whether the woman is pregnant or postpartum. Conventional pharmacologic treatment includes diuretics, angiotensin-converting enzyme inhibitors (postpartum only), vasodilators such as hydralazine, digoxin, β-blockers, and anticoagulants.This review contains 5 figures, 5 tables, and 36 references.Key Words: critical care obstetrics, ejection fraction, heart failure, left ventricular systolic dysfunction, management, maternal mortality, peripartum cardiomyopathy, preeclampsia, pregnancy
围产期心肌病(PPCM)是发生在妊娠晚期或产后早期的一种严重而罕见的疾病。它被定义为特发性,非家族性,非遗传性,在没有任何其他可识别的心脏病原因的情况下,在妊娠最后一个月或分娩后前5个月内发生的心力衰竭。在美国,每3千到4千名活产婴儿中就有1人患此病。左心室收缩功能不全,几乎总是导致左心室射血分数小于45%。PPCM的独特之处在于其快速的医学病程和倾向于在疾病发作的3至6个月内自行消退。死亡率很高,高达10%,在随后的怀孕中复发的风险也很高。PPCM的治疗根据妇女是否怀孕或产后略有不同。传统的药物治疗包括利尿剂、血管紧张素转换酶抑制剂(仅限产后)、血管扩张剂,如肼嗪、地高辛、β受体阻滞剂和抗凝血剂。本综述包含5张图,5张表,36篇参考文献。关键词:重症产科,射血分数,心力衰竭,左室收缩功能障碍,管理,产妇死亡率,围产期心肌病,先兆子痫,妊娠
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引用次数: 0
Bacterial Infections in Pregnancy 妊娠期细菌感染
Pub Date : 2018-11-06 DOI: 10.2310/obg.19047
P. Duff, J. Jackson
All pregnant women should be screened on the first prenatal visit for chlamydia infection and gonorrhea. High-risk patients should be rescreened in the third trimester. Patients with symptomatic bacterial vaginosis should be treated with metronidazole to prevent complications such as preterm delivery, chorioamnionitis, and puerperal endometritis. All patients should be screened for GBS infection at 35 to 37 weeks and treated intrapartum with prophylactic antibiotics if they test positive. Prompt diagnosis and treatment of chorioamnionitis are essential to prevent neonatal and maternal complications. The treatment of choice intrapartum is ampicillin plus gentamicin. Patients who require cesarean delivery should also receive either clindamycin or metronidazole postpartum to strengthen coverage against anaerobes. Two highly effective treatment regimens for puerperal endometritis are clindamycin plus gentamicin or metronidazole plus ampicillin plus gentamicin.This review contains 5 figures, 7 tables and 43 references.Key Words: bacterial vaginosis, chorioamnionitis, lower genital tract infection, puerperal infection, urinary tract infection
所有孕妇应在第一次产前检查时进行衣原体感染和淋病筛查。高危患者应在妊娠晚期重新筛查。有症状性细菌性阴道病的患者应应用甲硝唑治疗,防止早产、绒毛膜羊膜炎、产褥期子宫内膜炎等并发症的发生。所有患者应在35至37周时接受GBS感染筛查,如果检测呈阳性,应在分娩时使用预防性抗生素治疗。及时诊断和治疗绒毛膜羊膜炎对于预防新生儿和产妇并发症至关重要。产时治疗选择氨苄西林加庆大霉素。需要剖宫产的患者也应在产后接受克林霉素或甲硝唑,以加强对厌氧菌的覆盖。两种非常有效的产后子宫内膜炎治疗方案是克林霉素加庆大霉素或甲硝唑加氨苄西林加庆大霉素。本文共包含图5张,表7张,文献43篇。关键词:细菌性阴道病,绒毛膜羊膜炎,下生殖道感染,产褥期感染,尿路感染
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引用次数: 0
Surgical Management of Fecal Incontinence 大便失禁的外科治疗
Pub Date : 2018-11-05 DOI: 10.2310/obg.19159
Asya Ofshteyn, D. Popowich
Fecal incontinence is a common yet socially stigmatized condition that results from a complex interplay of various etiologies. In commonly seen scenarios, obstetric injuries can result in fecal incontinence after assisted or uncomplicated vaginal births and can become symptomatic years after delivery. Postpartum women may initially present to their obstetrician-gynecologist or urogynecologist with fecal incontinence symptoms and require appropriate evaluation, initial management, and possible referral to further specialists. This chapter outlines the surgical assessment, work-up, and management of fecal incontinence.This review contains 21 figures, 1 tables, and 97 references.Keywords: Fecal incontinence, postpartum complications, pudendal nerve neuropathy, anal sphincter injury, operative management, preoperative workup, sacral nerve stimulation, MRI defecography, endanal ultrasound
大便失禁是一种常见的但社会污名的条件,结果从各种病因复杂的相互作用。在常见的情况下,产科损伤可导致辅助分娩或顺产后大便失禁,并可在分娩数年后出现症状。产后妇女最初可能会向妇产科医生或泌尿妇科医生提出大便失禁症状,需要适当的评估、初步处理,并可能转诊给进一步的专家。本章概述了大便失禁的手术评估、检查和处理。本综述包含21张图,1张表,97篇参考文献。关键词:大便失禁,产后并发症,阴部神经病变,肛门括约肌损伤,手术处理,术前检查,骶神经刺激,MRI排粪造影,肛管超声
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引用次数: 0
Nonobstetrical Surgical Conditions 非产科手术条件
Pub Date : 2018-10-23 DOI: 10.2310/obg.19061
S. Kim, Joong-Shin Park
Prompt diagnosis and appropriate interventions for nonobstetrical surgical emergencies are important in pregnancy because a delay in diagnosis can result in increased morbidity and mortality to both mother and fetus. Generally, neither anesthesia nor surgical procedures increase the risk of congenital malformations or miscarriage. The diagnosis of a surgical condition is often more difficult in pregnant women than in nonpregnant adults because the traditional signs and symptoms of a specific disorder may not be exhibited due to the anatomic and physiologic changes of pregnancy. Moreover, the surgeon may need to make accommodations and adjustments as a result of the anatomic and physiologic changes associated with pregnancy, which may include limitations imposed by uterine size, unusual clinical presentation, and adjustments to accommodate fetal monitoring and optimize fetal well-being. Therefore, a multidisciplinary team approach (involving obstetricians, general surgeons, anesthesiologists, and neonatologists) is required in nonobstetrical surgeries involving pregnant women.This review contains 3 figures, 3 tables, and 32 references.Key Words: adnexal torsion, anesthesia, appendicitis, cholecystitis, laparoscopy, pregnancy, radiation, surgery
对于妊娠期的非产科手术紧急情况,及时诊断和适当干预是很重要的,因为诊断的延迟可能导致母亲和胎儿的发病率和死亡率增加。一般来说,麻醉和外科手术都不会增加先天性畸形或流产的风险。由于妊娠解剖和生理的变化,可能无法表现出特定疾病的传统体征和症状,因此对孕妇的手术诊断往往比未怀孕的成年人更为困难。此外,由于与妊娠相关的解剖和生理变化,外科医生可能需要做出调整和调整,这可能包括子宫大小的限制,不寻常的临床表现,以及调整以适应胎儿监测和优化胎儿健康。因此,在涉及孕妇的非产科手术中,需要一个多学科的团队方法(包括产科医生、普通外科医生、麻醉师和新生儿科医生)。本综述包含3张图,3张表,32篇参考文献。关键词:附件扭转,麻醉,阑尾炎,胆囊炎,腹腔镜,妊娠,放疗,手术
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引用次数: 0
Sexual Dysfunction: Hypoactive Sexual Desire Disorder 性功能障碍:性欲减退
Pub Date : 2018-10-19 DOI: 10.2310/obg.19105
J. Buster
Healthy female sexual functioning is driven by sexual desire. Sexual desire, traditionally defined as sexual thoughts and fantasies, is a natural life force and an art form affecting all aspects of a woman’s interpersonal and professional life. Virtually, all diagnostic categories of female sexual dysfunction, including arousal disorder, anorgasmia, and sexual pain disorder are linked to, caused by, or aggravated by loss of sexual desire. Decreased sexual desire is a diagnosis (hypoactive sexual desire disorder, HSDD) with its own International Classification of Diseases code (F52.0).. Impact is often subtle. HSDD may express as seemingly unrelated emotional disturbances that degrade life quality in family relationships, in the workplace, or both. For some women, it is severely distracting. The diagnosis of HSDD is made when symptoms are sufficient to cause distress. In older women, HSDD is heavily impacted by menopause-associated withdrawal of reproductive hormones, particularly testosterone and estradiol. HSDD greatly improves with transdermal replacement of these steroids. Side effects of transdermal hormones are minimal but response can be gratifying. In premenopausal women, HSDD behaves more as a psychoendocrine disorder that is responsive in some patients to flibanserin, a nonhormonal 5-HT1A receptor agonist. Side effects of flibanserin are significant but manageable.This review contains 12 figures, 6 tables, and  references.Key Words: estradiol, flibanserin, hypoactive sexual desire disorder, menopause, selective serotonin reuptake inhibitors, sexual desire, sexuality, testosterone, transdermal, women
健康的女性性功能是由性欲驱动的。性欲,传统上被定义为性思想和性幻想,是一种自然的生命力和艺术形式,影响着女性人际关系和职业生活的各个方面。事实上,所有女性性功能障碍的诊断类别,包括性唤起障碍、性无高潮和性疼痛障碍,都与性欲丧失有关、由性欲丧失引起或因性欲丧失而加重。性欲减退是一种诊断(性欲减退症,HSDD),有自己的国际疾病分类代码(F52.0)。影响往往是微妙的。HSDD可能表现为看似无关的情绪障碍,降低家庭关系、工作场所或两者的生活质量。对一些女性来说,这严重分散了她们的注意力。当症状足以引起痛苦时,诊断为HSDD。在老年妇女中,HSDD受到与绝经相关的生殖激素,特别是睾酮和雌二醇的退出的严重影响。这些类固醇经皮替代后,HSDD显著改善。透皮激素的副作用很小,但反应令人满意。在绝经前妇女中,HSDD更多表现为一种心理内分泌障碍,在一些患者中对氟班色林(一种非激素5-HT1A受体激动剂)有反应。氟班色林的副作用很严重,但可以控制。本综述包含12个图,6个表和参考文献。关键词:雌二醇,氟班色林,性欲减退,更年期,选择性血清素再摄取抑制剂,性欲,性,睾酮,透皮,女性
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引用次数: 0
Sexual Assault 性侵犯
Pub Date : 2018-10-18 DOI: 10.2310/obg.19017
Nisha Verma, Celeste S Royce
Sexual assault affects as many as one-third of women around the world. Sexual assault includes individual traumatic events as well as chronic sexually abusive relationships, and can involve a partner, acquaintance, or stranger. Many women who have experienced sexual assault develop long-term mental and physical effects of their sexual trauma, including post-traumatic stress disorder, alcohol abuse, and dyspareunia. OBGYNs are able to have long-lasting impacts on the many survivors of sexual assault by screening effectively and providing compassionate, trauma-informed care.This review contains 10 figures and 33 references.Keywords: human trafficking, intimate partner violence, primary care, rape, sexual assault, sexual violence, trauma-informed care, women
性侵犯影响着全世界多达三分之一的女性。性侵犯包括个人创伤事件以及长期的性虐待关系,可能涉及伴侣、熟人或陌生人。许多遭受过性侵犯的妇女会因性创伤而产生长期的精神和身体影响,包括创伤后应激障碍、酗酒和性交困难。妇产科医生能够通过有效的筛查和提供富有同情心、了解创伤的护理,对许多性侵犯幸存者产生持久的影响。本综述包含10幅图和33篇参考文献。关键词:人口贩卖,亲密伴侣暴力,初级保健,强奸,性侵犯,性暴力,创伤知情护理,妇女
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引用次数: 0
Neurologic Diseases in Pregnancy 妊娠期神经系统疾病
Pub Date : 2018-09-25 DOI: 10.2310/obg.19044
Emily L. Johnson, P. Kaplan
Neurologic conditions commonly affect women during pregnancy. The severity of some chronic conditions, such as headaches, epilepsy, and multiple sclerosis, may be affected by pregnancy. Due to teratogenicity, some medications used prior to pregnancy should be avoided or used at a lower dose during pregnancy. The physiologic changes of pregnancy put women at risk for new neurologic conditions, including posterior reversible encephalopathy syndrome, venous sinus thrombosis, and restless legs syndrome. Compression neuropathies may arise during pregnancy or delivery. Increased experience with neuroimaging has provided reassurance that magnetic resonance imaging may be used safely during pregnancy.This review contains 7 figures, 7 tables, and 30 referencesKey Words: epilepsy, headache, multiple sclerosis, myasthenia gravis, neurology, neuropathy, pregnancy, posterior reversible encephalopathy syndrome, stroke, venous sinus thrombosis
神经系统疾病通常影响怀孕期间的妇女。一些慢性疾病的严重程度,如头痛、癫痫和多发性硬化症,可能会受到怀孕的影响。由于致畸性,怀孕前使用的一些药物应避免或在怀孕期间使用较低剂量。妊娠的生理变化使妇女有发生新的神经系统疾病的危险,包括后路可逆性脑病综合征、静脉窦血栓形成和不宁腿综合征。压缩性神经病可在怀孕或分娩期间出现。神经影像学经验的增加为磁共振成像在怀孕期间的安全使用提供了保证。关键词:癫痫、头痛、多发性硬化症、重症肌无力、神经病学、神经病变、妊娠、后可逆性脑病综合征、脑卒中、静脉窦血栓形成
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引用次数: 0
In Vitro Fertilization 体外受精
Pub Date : 2018-09-20 DOI: 10.2310/obg.19099
J. Zolton, R. Chattopadhyay, A. DeCherney
Assisted reproductive technology (ART) encompasses all procedures that manipulate the oocytes, sperm, and embryos outside of the body. Decades of research have allowed the field to emerge as a reliable and safe treatment for infertile men and women. Indications for in vitro fertilization (IVF) include tubal factor infertility, anovulation, male factor infertility, and decreased ovarian reserve. Treatment is not limited to the infertile population, as IVF with preimplantation genetic diagnosis also offers patients an opportunity to prevent transmission of a genetic condition for which they have been found to carry. The field of ART continues to rapidly evolve, as more knowledge is gained from studies reporting on ovarian stimulation protocols, reproductive techniques such as intracytoplasmic sperm injection, and blastocyst transfer. Techniques are aimed to improve live birth rates while ensuring the optimal health of children conceived using IVF.This review contains 8 figures, 5 tables and 63 referencesKey Words: assisted reproductive technology, blastocyst, decreased ovarian reserve, embryo transfer, gonadotropin-releasing hormone agonist, gonadotropin-releasing hormone antagonist, intracytoplasmic sperm injection, luteal phase support, ovarian hyperstimulation syndrome, vitrification
辅助生殖技术(ART)包括在体外操纵卵母细胞、精子和胚胎的所有程序。几十年的研究使该领域成为一种可靠和安全的治疗不育男性和女性的方法。体外受精(IVF)的适应症包括输卵管因素不育、无排卵、男性因素不育和卵巢储备减少。治疗并不局限于不育人群,因为植入前遗传学诊断的体外受精也为患者提供了一个机会,以防止他们已经发现携带的遗传疾病的传播。随着对卵巢刺激方案、生殖技术(如胞浆内单精子注射和囊胚移植)的研究报告获得更多知识,抗逆转录病毒治疗领域继续迅速发展。技术旨在提高活产率,同时确保使用体外受精怀孕的儿童的最佳健康。关键词:辅助生殖技术,囊胚,卵巢储备减少,胚胎移植,促性腺激素释放激素激动剂,促性腺激素释放激素拮抗剂,卵浆内单精子注射,黄体期支持,卵巢过度刺激综合征,玻璃化
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引用次数: 0
Nonsurgical Management Options for Pelvic Organ Prolapse: Review of the Current Evidence 盆腔器官脱垂的非手术治疗选择:当前证据的回顾
Pub Date : 2018-09-12 DOI: 10.2310/obg.19156
Nathan Kow
Pelvic organ prolapse (POP) is a common disorder that impacts a woman’s quality of life and has been projected to increase in the near future. Although many different treatments are currently available, healthcare practioners should be familiar with the common nonsurgical options that are considered the first-line therapy. Advances in nonsurgical interventions have traditionally included pessaries and pelvic floor muscle therapy.  These optiosn have not changed much over time, however there have been recent trials providing more evidence with regards to their efficacy.  The objective of this article is to review the current evidence for nonsurgical treatment options for POP. This review contains 2 tables and 19 referencesKey Words: pelvic floor muscle training, pelvic floor physical therapy, pelvic organ prolapse, pessary, kegel excercises, uterine prolapse, cystocele, rectocele
盆腔器官脱垂(POP)是一种影响女性生活质量的常见疾病,预计在不久的将来会增加。虽然目前有许多不同的治疗方法,但保健医生应该熟悉被认为是一线治疗的常见非手术选择。非手术干预的进展传统上包括子宫托和盆底肌肉治疗。随着时间的推移,这些选择并没有发生太大的变化,然而,最近的试验提供了更多关于其疗效的证据。本文的目的是回顾目前的证据,非手术治疗方案的POP。关键词:盆底肌肉训练,盆底物理治疗,盆腔器官脱垂,子宫托,凯格尔运动,子宫脱垂,膀胱膨出,直肠膨出
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引用次数: 0
期刊
DeckerMed Obstetrics and Gynecology
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