{"title":"Vegetation size: a key metric in the team effort for treating infective endocarditis.","authors":"Lauge Østergaard, Emil Fosbøl","doi":"10.1093/ehjci/jeag071","DOIUrl":"https://doi.org/10.1093/ehjci/jeag071","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147462737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Claire Lucas, Mary Philip, Karine Nguyen, Victor Morel, Laetitia Tessonnier, Gilbert Habib
{"title":"Intense Myocardial Uptake in a Patient with Fabry Disease - a new cause of false positive of Bone Scintigraphy mimicking cardiac amyloidosis.","authors":"Claire Lucas, Mary Philip, Karine Nguyen, Victor Morel, Laetitia Tessonnier, Gilbert Habib","doi":"10.1093/ehjci/jeag072","DOIUrl":"https://doi.org/10.1093/ehjci/jeag072","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147431704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nobuyuki Ohte, Otto A Smiseth, Shohei Kikuchi, Shuichi Kitada, Yu Kawada, Yoshihiro Seo
Aims: Impaired left ventricular (LV) relaxation, often assessed noninvasively by reduced early diastolic mitral annular velocity (e'); however, it is age dependent. We re-investigated the relationship between e' and the invasively measured LV relaxation time constant (τ), while accounting for LV geometry, body mass index (BMI), blood pressure, heart rate, and age, established HF risk markers.
Methods and results: We analyzed 419 patients with suspected coronary artery disease undergoing left heart catheterization. The τ was measured using micromanometer recordings, LV volumes by ventriculography, and mean e' (average of septal and lateral e') by echocardiography. Linear and multivariable regression analyses were used to examine relationships between e' and τ and to determine the influence of BMI, blood pressure, age, and LV geometry. Mean e' correlated weakly but significantly with τ (r=-0.27, P<0.001). In multivariable analysis, LV end-systolic volume index (LVESVI) (β=0.520, P<0.001), heart rate (β=-0.426, P<0.001), BMI (β=0.110, P=0.002), and mean e' (β=-0.088, P=0.019) were independent determinants of τ (R2=0.490), whereas age was not. Predictors of e' included age (β=-0.467, P<0.001), LVESVI (β=-0.368, P<0.001), and BMI (β=-0.101, P=0.015) (R2=0.348). τ did not independently predict e'.
Conclusions: In this cohort, e' and τ showed only a modest association. LV geometry and BMI were independent contributors to both τ and e', while age did not significantly affect τ. The determinants of τ and the mean e' partially overlap and have distinct physiological bases. An increased BMI is associated with impaired LV relaxation.
{"title":"Predictive value of early diastolic mitral annular velocity and body mass index as markers of left ventricular relaxation: Validation against invasive time constant of relaxation.","authors":"Nobuyuki Ohte, Otto A Smiseth, Shohei Kikuchi, Shuichi Kitada, Yu Kawada, Yoshihiro Seo","doi":"10.1093/ehjci/jeag067","DOIUrl":"https://doi.org/10.1093/ehjci/jeag067","url":null,"abstract":"<p><strong>Aims: </strong>Impaired left ventricular (LV) relaxation, often assessed noninvasively by reduced early diastolic mitral annular velocity (e'); however, it is age dependent. We re-investigated the relationship between e' and the invasively measured LV relaxation time constant (τ), while accounting for LV geometry, body mass index (BMI), blood pressure, heart rate, and age, established HF risk markers.</p><p><strong>Methods and results: </strong>We analyzed 419 patients with suspected coronary artery disease undergoing left heart catheterization. The τ was measured using micromanometer recordings, LV volumes by ventriculography, and mean e' (average of septal and lateral e') by echocardiography. Linear and multivariable regression analyses were used to examine relationships between e' and τ and to determine the influence of BMI, blood pressure, age, and LV geometry. Mean e' correlated weakly but significantly with τ (r=-0.27, P<0.001). In multivariable analysis, LV end-systolic volume index (LVESVI) (β=0.520, P<0.001), heart rate (β=-0.426, P<0.001), BMI (β=0.110, P=0.002), and mean e' (β=-0.088, P=0.019) were independent determinants of τ (R2=0.490), whereas age was not. Predictors of e' included age (β=-0.467, P<0.001), LVESVI (β=-0.368, P<0.001), and BMI (β=-0.101, P=0.015) (R2=0.348). τ did not independently predict e'.</p><p><strong>Conclusions: </strong>In this cohort, e' and τ showed only a modest association. LV geometry and BMI were independent contributors to both τ and e', while age did not significantly affect τ. The determinants of τ and the mean e' partially overlap and have distinct physiological bases. An increased BMI is associated with impaired LV relaxation.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2026-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147344051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Restless until it rests: appraising LV filling pressures through CMR contrast kinetics.","authors":"Per M Arvidsson, Ellen Ostenfeld","doi":"10.1093/ehjci/jeaf314","DOIUrl":"10.1093/ehjci/jeaf314","url":null,"abstract":"","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":"478-479"},"PeriodicalIF":6.6,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145596216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexandra Clement, Denisa Muraru, Marco Penso, Michele Tomaselli, Noela Radu, Alexandra S Buta, Samantha Fisicaro, Valeria Rella, Paolo Springhetti, Yuka Kawada, Giorgia Benzoni, Cristian Statescu, Radu Sascau, Luigi P Badano
Background and aims: In secondary tricuspid regurgitation (STR) patients, the clinical value of right atrioventricular coupling (RAVC) and right atrial (RA) stiffness indices has never been evaluated. Accordingly, we explored the association with a composite outcome of all-cause mortality or heart failure hospitalization of: 1) RAVC index obtained either with speckle tracking echocardiography (RAVCSTE) or as the ratio between RA volume (RAV) and right ventricular (RV) stroke volume (RAVCVOL), and 2) RA stiffness index calculated as the ratio between RAV index and RA longitudinal reservoir strain (RALS).
Methods: 513 patients with mild-to-severe STR (75±13 years, 58% severe) were included.
Results: After a mean follow-up of 18±15 months, 195 patients (38%) reached the composite endpoint. On spline curve modeling, the cut-off values associated with increased two-year event rates were: (1) <0.82 for RAVCSTE (reduced values of the ratio between RALS and RV free wall strain indicating impaired coupling, the RA not supporting effectively the RV filling, despite a good systolic function of the RV); (2) >1.23 for RAVCVOL (higher values suggesting greater RA remodeling relative to RV stroke volume and altered coupling); (3) >4.6 for RA stiffness index (higher values indicating a diminished RA compliance to filling). However, in multivariable Cox regression analyses and hierarchical χ2 analyses, only RAVCVOL maintained a significant association with the outcome (p<0.05).
Conclusions: In STR patients, RAVC and RA stiffness indices are associated with the risk of events, with RAVCVOL yielding the strongest association.
{"title":"Association of Right Atrioventricular Coupling Indices and Right Atrial Stiffness Index with Outcome in Secondary Tricuspid Regurgitation.","authors":"Alexandra Clement, Denisa Muraru, Marco Penso, Michele Tomaselli, Noela Radu, Alexandra S Buta, Samantha Fisicaro, Valeria Rella, Paolo Springhetti, Yuka Kawada, Giorgia Benzoni, Cristian Statescu, Radu Sascau, Luigi P Badano","doi":"10.1093/ehjci/jeag062","DOIUrl":"https://doi.org/10.1093/ehjci/jeag062","url":null,"abstract":"<p><strong>Background and aims: </strong>In secondary tricuspid regurgitation (STR) patients, the clinical value of right atrioventricular coupling (RAVC) and right atrial (RA) stiffness indices has never been evaluated. Accordingly, we explored the association with a composite outcome of all-cause mortality or heart failure hospitalization of: 1) RAVC index obtained either with speckle tracking echocardiography (RAVCSTE) or as the ratio between RA volume (RAV) and right ventricular (RV) stroke volume (RAVCVOL), and 2) RA stiffness index calculated as the ratio between RAV index and RA longitudinal reservoir strain (RALS).</p><p><strong>Methods: </strong>513 patients with mild-to-severe STR (75±13 years, 58% severe) were included.</p><p><strong>Results: </strong>After a mean follow-up of 18±15 months, 195 patients (38%) reached the composite endpoint. On spline curve modeling, the cut-off values associated with increased two-year event rates were: (1) <0.82 for RAVCSTE (reduced values of the ratio between RALS and RV free wall strain indicating impaired coupling, the RA not supporting effectively the RV filling, despite a good systolic function of the RV); (2) >1.23 for RAVCVOL (higher values suggesting greater RA remodeling relative to RV stroke volume and altered coupling); (3) >4.6 for RA stiffness index (higher values indicating a diminished RA compliance to filling). However, in multivariable Cox regression analyses and hierarchical χ2 analyses, only RAVCVOL maintained a significant association with the outcome (p<0.05).</p><p><strong>Conclusions: </strong>In STR patients, RAVC and RA stiffness indices are associated with the risk of events, with RAVCVOL yielding the strongest association.</p>","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147316894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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