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Study of Arterial supply to Sinoatrial Node in Normal Human Hearts 正常人心脏窦房结动脉供应的研究
Pub Date : 2019-05-15 DOI: 10.46319/rjmahs.2019.v02i01.003
R LakshmiPrabha, P. Ramesh, Khizer Hussain Afroze, Kavyashree An, D. Anupama
Introduction: The arterial supply to Sino-Atrial Node (SA Node) and its variations is of great importance in increasing use of cardiac interventional procedures. Aim and objective: The aim of present study is to analyze the arterial supply of SA node. Materials and Methods: Fifty-five human hearts, fixed in the formalin solution were dissected and artery to SA node was traced. Results: Out of 55 cases, SA nodal artery originated from right coronary artery (RCA) in 64%, left circumflex artery (LCX) in 34% and 2% from both. S-shaped SA nodal artery was seen in 2 cases. In most of the specimens (42 out of 55) SA nodal artery formed a ring around superior vena cava and in all the cases, the branches of SA nodal artery supplied to both atria and auricle based on the origin either from RCA or LCX. Conclusion: Variations in arterial supply to SA node will be helpful to interventional cardiac surgeons.
导论:窦房结的动脉供应及其变化在心脏介入手术的应用中具有重要意义。目的与目的:分析窦房结的动脉供应情况。材料与方法:解剖55颗固定在福尔马林溶液中的人心脏,追踪动脉至窦房结。结果:55例小结动脉起源于右冠状动脉(RCA)的占64%,起源于左旋动脉(LCX)的占34%,起源于两者的占2%。2例可见s型SA结动脉。大多数标本(55例中有42例)的SA结动脉在上腔静脉周围形成环状,所有病例的SA结动脉分支均根据RCA或LCX的起源供应心房和耳廓。结论:窦房结动脉供应的变化有助于心脏介入手术。
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引用次数: 0
Risk of Insulin Resistance in Normal Glucose Tolerant Subjects 正常葡萄糖耐受性受试者胰岛素抵抗的风险
Pub Date : 2019-05-15 DOI: 10.46319/rjmahs.2019.v02i01.004
Dr.S.Vijaya kumar, Bhargavi Sk, D. Lakshmi, Sathisha Tg, Hamsaveena
Introduction : Metabolic syndrome (MS) , with its huge baggage of complications , is emerging as a major threat to lead a healthy life, worldwide. Sedentary habits, urbanization, life style modifications, stress and anxiety contribute to its increasing incidence, not to mention diabetes and hypertension. Routine screening for diabetes fails to detect early MS. Materials and methods: 55 normal glucose tolerant (NGT) subjects, both males & females were selected for the study. Based on modified National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III criteria (Waist circumference-WC 80 cm FM, 90 cm M), they were grouped into - with and without metabolic syndrome (MS). Fasting blood glucose, total cholesterol, triglycerides, insulin levels and high density lipoprotein were estimated. Insulin resistance (IR) was calculated by HOMAIR formula. Results : TGL and insulin levels were elevated and HDL levels were decreased in MS group compared to those without MS & this was statistically significant. Among the 55 NGT subjects, 30 people had MS. The prevalence of MS was 43% and the prevalence of IR among NGT was 31% . Conclusion: Metabolic syndrome & IR occur in subjects with normal glucose tolerance also. Hence, screening of vulnerable people for MS should be done to detect potential diabetes mellitus (DM) & coronary artery disease (CAD) in early stages.
导言:代谢综合征(MS)伴随大量并发症,正在成为全球健康生活的主要威胁。久坐不动的习惯、城市化、生活方式的改变、压力和焦虑导致其发病率增加,更不用说糖尿病和高血压了。资料和方法:选择55例正常糖耐量(NGT)受试者,男女均可。根据修改后的国家胆固醇教育计划(NCEP)成人治疗小组(ATP) III标准(腰围-腰围80 cm FM, 90 cm M),将患者分为有无代谢综合征(MS)两组。评估空腹血糖、总胆固醇、甘油三酯、胰岛素水平和高密度脂蛋白。胰岛素抵抗(IR)采用HOMAIR公式计算。结果:与非MS组相比,MS组TGL、胰岛素水平升高,HDL水平降低,差异有统计学意义。55例NGT患者中有30例MS,其中MS患病率为43%,IR患病率为31%。结论:糖耐量正常的受试者也会出现代谢综合征和IR。因此,应该对易感人群进行MS筛查,在早期发现潜在的糖尿病(DM)和冠状动脉疾病(CAD)。
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引用次数: 0
Co-existence of Sarcoidosis of Cervical Lymph Nodes and Breast Carcinoma - a rare case report and review of literature 颈部淋巴结结节病与乳腺癌共存一例罕见病例报告及文献复习
Pub Date : 2019-05-15 DOI: 10.46319/rjmahs.2019.v02i01.010
Avinash Mj
Sarcoidosis is a chronic disease affecting multiple systems and is characterized by non-caseating granulomas. It is of unknown etiology. In some cases it is very difficult to differentially diagnose sarcoidosis from malignancy just by clinical and radiological features in spite of modern imaging modalities like PET-CT Scan. Its association with solid organ malignancy is rare. The only accurate way to demonstrate and differentiate sarcoidosis from malignancy is histopathological examination. We report a rare case of Sarcoidosis affecting right sided cervical lymphnodes coexisting in a patient with left sided breast carcinoma.
结节病是一种影响多系统的慢性疾病,以非干酪化肉芽肿为特征。病因不明。在某些情况下,尽管有像PET-CT扫描这样的现代成像方式,仅凭临床和放射学特征很难鉴别结节病和恶性肿瘤。它与实体器官恶性肿瘤的关联是罕见的。鉴别结节病与恶性肿瘤的唯一准确方法是组织病理学检查。我们报告一例罕见的结节病影响右侧颈部淋巴结共存的病人与左侧乳腺癌。
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引用次数: 0
MCI curriculum -2019 MCI课程-2019
Pub Date : 2019-05-15 DOI: 10.46319/rjmahs.2019.v02i01.001
Dr Shashiraj H K
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引用次数: 0
Urinary tract infections due to Amp C b-Lactamase producing gram negative bacteria 由Amp C b-内酰胺酶产生的革兰氏阴性菌引起的尿路感染
Pub Date : 2019-05-15 DOI: 10.46319/rjmahs.2019.v02i01.005
Dr Sangeetha K, D. Sm, D. Gs, Dr Raksha Y
Introduction: The exact occurrence of extended spectrum β-lactamase (ESBL) and AmpC β -lactamase production among uropathogenic bacteria is not known. Infections with drug resistant urinary pathogens have limited therapeutic options. Hence this study was conducted to know the occurrence of AmpC β-lactamase production among gram negative bacteria (GNB) causing urinary tract infection (UTI). Materials and Methods : The urine samples submitted to Department of Microbiology from 1st March 2016 to 30th April 2016 were studied. All the samples were plated on sheep blood agar and MacConkey's agar. The isolates were identified and Antibiotic susceptibility testing was done. AmpC β -lactamase and ESBL detection was done as described previously. The results were tabulated. Results: This study was conducted on 900 urine samples. Total 144 (16%) GNB were isolated. E coli was the most common isolate followed by non-fermenting gram negative bacteria (NFGNB). AmpC β -lactamase production was seen in 75 (52.1%) isolates and ESBL production was seen in 60 isolates (41.7%). Total 27 (18.7%) isolates showed multidrug resistant (MDR) phenotypes and 23/27 were AmpC β -lactamase producers. Conclusion: Routine detection of ESBL and AmpC β -lactamase is required to choose appropriate therapy. Judicious use of antibiotics should be done in clinical settings. Imipenem can be used as an empirical antibiotic for complicated urinary tract infection.
导言:尿路致病菌中扩展谱β-内酰胺酶(ESBL)和AmpC β-内酰胺酶产生的确切发生尚不清楚。泌尿系统耐药病原体感染的治疗选择有限。因此,本研究旨在了解引起尿路感染(UTI)的革兰氏阴性菌(GNB)产生AmpC β-内酰胺酶的情况。材料与方法:对2016年3月1日至2016年4月30日提交微生物学系的尿样进行分析。所有样品均镀于羊血琼脂和麦康基琼脂上。对分离菌株进行鉴定并进行药敏试验。AmpC β -内酰胺酶和ESBL检测如前所述。结果被制成表格。结果:本研究对900份尿样进行了研究。共分离GNB 144例(16%)。大肠杆菌是最常见的分离物,其次是非发酵革兰氏阴性菌(NFGNB)。75株(52.1%)菌株产生AmpC β -内酰胺酶,60株(41.7%)菌株产生ESBL。共有27株(18.7%)呈现耐多药表型,其中23/27株为AmpC β -内酰胺酶产生菌。结论:应常规检测ESBL和AmpC β -内酰胺酶,选择合适的治疗方法。临床应谨慎使用抗生素。亚胺培南可作为治疗复杂性尿路感染的经验性抗生素。
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引用次数: 0
Study of Levonorgestrel IUCD In Management Of Dysfunctional Uterine Bleeding 左炔诺孕酮宫内节育器治疗功能失调性子宫出血的研究
Pub Date : 2019-05-15 DOI: 10.46319/rjmahs.2019.v02i01.006
B. Thanmaye, B. Dhananjaya
Introduction: Dysfunctional uterine bleeding (DUB) is a common problem in women which causes discomfort and decreases the quality of life. About 10-15% of women experience episodes of DUB at some point of time during the reproductive years of their lives. Annually 5-19% of women seek medical care. It accounts for more than 25% of all hysterectomies. Many treatment options are available. Objectives: To study efficacy of levonorgestrel IUCD in terms of blood loss, endometrial thickness, hemoglobin concentration and to evaluate side effects in DUB. Materials and methods: 40 women presenting with dysfunctional uterine bleeding were treated with levonorgestrel IUCD. The primary outcome in the study was reduction in menstrual loss measured using pictorial blood loss assessment chart (PBAC) score, increase in blood hemoglobin levels, reduction in thickness of
功能失调性子宫出血(DUB)是女性的常见问题,它会引起不适并降低生活质量。大约10-15%的妇女在其生育年龄的某个时间点经历过DUB发作。每年有5-19%的妇女寻求医疗保健。它占所有子宫切除术的25%以上。有许多治疗方案可供选择。目的:探讨左炔诺孕酮IUCD在DUB患者失血量、子宫内膜厚度、血红蛋白浓度等方面的疗效,并评价其不良反应。材料与方法:采用左炔诺孕酮宫内节育器治疗功能失调性子宫出血40例。该研究的主要结果是使用图像失血评估图(PBAC)评分测量月经损失减少,血液血红蛋白水平增加,厚度减少
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引用次数: 0
A rare case of Systemic Lupus Erythematosus with Congenital Bifid Tongue 系统性红斑狼疮合并先天性舌裂1例
Pub Date : 2019-05-15 DOI: 10.46319/rjmahs.2019.v02i01.009
Veena Thimmappa, G. NeethuMary, G. Narendra, L. Subhash, Harshal Kl
Systemic Lupus Erythematosus (SLE) is an autoimmune disorder with multiple aetiology, presents with varied cutaneous manifestations and systemic involvement, primarily affects women in her child bearing age. Congenital bifid tongue is an anomaly due to nonfusion of the two lingual swellings. It can occur either as an isolated entity or in association with syndromes like Opitz G syndrome, Oral-Facial-Digital syndrome type I, Klippel Feil anomaly and Larsen syndrome or even as very rare feature in infants born to diabetic mothers. We present a case report of 23 year old female, a second child from a nonconsanguineous marriage with no significant antenatal or postnatal history, diagnosed of SLE. She had secondary amenorrhoea and hypothyroidism, examination revealed reduced secondary sexual characteristics, short stature, orbital hypertelorism and a bifid tongue which was present since birth. Recent studies suggest there is increased risk of autoimmune diseases particularly SLE development via the gene transmitted by X chromosome. It is also found that SLE patients are commonly associated with X chromosome polysomy. This case is unusual as the patient had multiple features suggesting genetic involvement, both SLE and bifid tongue is individually found to have genetic roots and till date there is no single case of SLE with a congenital bifid tongue in literature.
系统性红斑狼疮(SLE)是一种多种病因的自身免疫性疾病,表现为多种皮肤表现和全身累及,主要影响育龄妇女。先天性舌裂是一种异常,由于两舌肿胀不融合。它既可以作为一个孤立的个体发生,也可以与Opitz G综合征、I型口-面-指综合征、Klippel Feil异常和Larsen综合征等综合征相关,甚至在糖尿病母亲所生的婴儿中作为非常罕见的特征发生。我们报告一例23岁女性,非近亲婚姻的第二个孩子,没有明显的产前或产后病史,被诊断为SLE。继发性闭经和甲状腺功能减退,检查发现第二性征减少,身材矮小,眼眶远端畸形,出生时就有舌裂。最近的研究表明,通过X染色体传播的基因,自身免疫性疾病特别是SLE的风险增加。研究还发现SLE患者通常与X染色体多体相关。这个病例是不寻常的,因为患者有多种特征表明遗传参与,SLE和舌裂都被单独发现有遗传根源,到目前为止,文献中还没有一例SLE合并先天性舌裂。
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引用次数: 0
Assessment of Severity of Panic Disorder with co-morbid Depression and quality of life 惊恐障碍伴抑郁的严重程度与生活质量评估
Pub Date : 2019-05-15 DOI: 10.46319/rjmahs.2019.v02i01.002
Dutta Abhishek, D. Mt, Dr. Swarna Buddha Nayok, D. Akshatha
Background: Panic disorder alone or when co-morbid with depression can severely affect the functioning of an individual. Aim: To determine the occurrence of panic disorder and co-morbid depression and their quality of life. Material and Methods: Thirty patients from psychiatry ward and out-patient department were assessed by Panic Disorder Severity Scale, Hamilton Depression Rating Scale and World Health Organization Quality Of Life for severity of panic attacks, co-morbid depression and life quality. Results: Most patients showed moderate (56.6%) to slight (36.6%) severity of panic symptoms. Of them,80% had depression. In them, 33.3% had mild and 26.6% moderate levels of depression. Quality of life was moderate in 40% and poor in 36.66%. Conclusion: Patients with panic disorder have high frequency of co-morbid depression, however severity of both needs to be assessed separately. Those who have higher severity of both or depression have poor life quality.
背景:惊恐障碍单独或与抑郁症合并症会严重影响个体的功能。目的:了解惊恐障碍和合并抑郁的发生情况及其生活质量。材料与方法:采用惊恐障碍严重程度量表、汉密尔顿抑郁评定量表和世界卫生组织生活质量量表对30例精神科和门诊患者的惊恐发作严重程度、共病抑郁和生活质量进行评估。结果:大多数患者表现为中度(56.6%)至轻度(36.6%)的恐慌症状严重程度。其中80%患有抑郁症。其中,33.3%的人患有轻度抑郁症,26.6%的人患有中度抑郁症。生活质量为中等的占40%,较差的占36.66%。结论:惊恐障碍患者合并抑郁的频率较高,但两者的严重程度需要单独评估。两种症状都较严重的人生活质量较差。
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引用次数: 0
Peripartum Cardiomyopathy
Pub Date : 2018-07-09 DOI: 10.46319/rjmahs.2018.v01i01.010
L. Dwarakanath, B. Girish, K. Hema, N. Rekha, Sahu Samra, S. Shazi
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引用次数: 0
Retroperitoneal Pheochromocytoma: A Rare Tumour Presenting as Ovarian Mass 腹膜后嗜铬细胞瘤:以卵巢肿块表现的罕见肿瘤
Pub Date : 2018-07-09 DOI: 10.46319/rjmahs.2018.v01i01.009
B. Dhananjaya, B. Thanmaye, G. Sowmya, M. Naveen
A 40 year old patient suffering from vague pain in the abdomen since 1 month, came with CT scan of abdomen and pelvis showing large lobulated cystic lesion of 11 x 10.6 x 9.7cms suggesting ? Left ovarian neoplasm. On exploratory laparotomy uterus and ovaries were normal and a mass of 10 x 9 cm was seen arising from the pelvis. The Histopathological report stated pheochromocytoma. The extra adrenal pheochromocytomas are rare tumors that originate from the chromaffin tissue of sympathetic nervous system.
患者40岁,腹部隐隐约约疼痛1个月,腹部及骨盆CT显示大分叶状囊性病变,11 × 10.6 × 9.7cm,提示?左卵巢肿瘤。剖腹探查时,子宫和卵巢正常,骨盆处可见一个10 × 9厘米的肿块。组织病理学报告为嗜铬细胞瘤。肾上腺外嗜铬细胞瘤是一种罕见的肿瘤,起源于交感神经系统的嗜铬组织。
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引用次数: 0
期刊
Research Journal of Medical and Allied Health Sciences
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