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Retrospective analysis of a case report of a left ovarian ectopic pregnancy after the former tubal 前输卵管后左卵巢异位妊娠1例回顾性分析
Q3 Medicine Pub Date : 2023-03-09 DOI: 10.24425/fmc.2022.142372
Anna Wrona, Veronika Aleksandrovych, Anna Gil, Magdalena Kurnik-Łucka, Jerzy A Walocha, Krzysztof Gil
Up to 2% of pregnancies may be extrauterine. Despite reproductive problems, they might increase the risk of serious complications. We present a case report of a 31-year-old woman with two extrauterine pregnancies - tubal and ovarian, which occurred at the same side with little time difference. In addition, we aimed to examine possible reasons underlying this rare pathology. Thus, surgically removed tissue specimens were morphologically assessed and further compared with specimens from healthy control patients. Telocytes were analysed in detail due to their pivotal role in the female reproductive system. Our study had observational character and obvious limitations typical for a clinical case. Yet, such a clinical case of two ectopic pregnancies has not been previously reported in the literature.
高达2%的妊娠可能是宫外妊娠。尽管存在生殖问题,但它们可能会增加严重并发症的风险。我们报告了一例31岁的女性有两个子宫外妊娠-输卵管和卵巢,发生在同一侧,几乎没有时间差异。此外,我们的目的是研究这种罕见病理的可能原因。因此,对手术切除的组织标本进行形态学评估,并进一步与健康对照患者的标本进行比较。由于远端细胞在女性生殖系统中的关键作用,我们对它们进行了详细的分析。本研究具有临床病例典型的观察性特征和明显的局限性。然而,这种两次异位妊娠的临床病例在以前的文献中尚未报道。
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引用次数: 0
Higher milk consumption is not associated with fracture risk reduction: systematic review and meta-analysis 高牛奶消费量与骨折风险降低无关:系统回顾和荟萃分析
Q3 Medicine Pub Date : 2023-03-09 DOI: 10.24425/fmc.2022.144088
Grzegorz Goncerz, Patrycja Kojm, Sylwia Skocelas, Krzysztof Więckowski, Tomasz Gallina, Paulina Pietrzyk, Sebastian Goncerz
Osteoporosis affects over 200 million people worldwide causing nearly 9 million fractures annually, with more than half in America and Europe.This meta-analysis was conducted to investigate whether low milk intake is associated with an increased risk of fractures by summarizing all the available evidence.Relevant studies were identified by searching the PubMed and EMBASE databases up to June 2020. The pooled relative risks with 95% confidence intervals were calculated.In a meta-regression analysis of 20 included studies (11 cohort and 9 case-control studies), a higher milk intake was not associated with a reduction in the total fracture risk in both sexes (OR 0.95, 95% CI: 0.84- 1.08), either in cohort (OR 0.91; 95% CI: 0.79-1.05) or case-control studies (OR 1.09; 95% CI: 0.82-1.44), as well as separately in men (OR 0.87; 95% CI: 0.71-1.07) and women (OR 0.95; 95% CI: 0.80-1.13).Higher milk consumption is not associated with fracture risk reduction and should not be recommended for fracture prevention.
骨质疏松症影响全球超过2亿人,每年造成近900万例骨折,其中一半以上发生在美国和欧洲。这项荟萃分析是通过总结所有现有证据来调查低牛奶摄入量是否与骨折风险增加有关。通过检索截至2020年6月的PubMed和EMBASE数据库确定相关研究。以95%置信区间计算合并相对危险度。在20项纳入研究(11项队列研究和9项病例对照研究)的荟萃回归分析中,高牛奶摄入量与两性总骨折风险降低无关(OR 0.95, 95% CI: 0.84- 1.08),无论是队列研究(OR 0.91;95% CI: 0.79-1.05)或病例对照研究(or 1.09;95% CI: 0.82-1.44),以及单独在男性中(OR 0.87;95% CI: 0.71-1.07)和女性(OR 0.95;95% ci: 0.80-1.13)。高牛奶摄入量与骨折风险降低无关,不应被推荐用于预防骨折。
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引用次数: 0
Habits related to the use of insulin infusion set in patients with type 1 diabetes on pump therapy — the effect of the educational intervention 1型糖尿病患者胰岛素输液器使用习惯对泵治疗的影响——教育干预的效果
Q3 Medicine Pub Date : 2023-03-09 DOI: 10.24425/fmc.2022.144079
Damian Ucieklak, Sandra Mrozińska, Aleksandra Wojnarska, Maciej T Małecki, Tomasz Klupa, Bartłomiej Matejko
Proper use of insulin infusion sets (IIS) plays an important role in pump therapy of patients with type 1 diabetes mellitus (T1DM). We assessed the habits associated with the use of IIS in patients with T1DM treated with insulin pump.This study included 79 T1DM patients who were examined for the presence of lipohypertrophy (LH) and retrained for proper IIS use. They completed a standard questionnaire regarding IIS at the time of study entry and at the follow-up. R e s u l t s: At baseline, most of the patients declared to have been using a plastic cannula (n = 68; 86.1%), changing the infusion set regularly (n = 65; 82.3%), and placing the infusion sets on the abdomen wall (n = 68; 86.1%). The most common rotation habit was the "curve pattern" on both sides of the umbilicus (n = 16; 20.3%). After a median of 23 weeks (IQR 20-34), 58 patients were available for the follow-up. A rise in the proportion of patients who declared to change IIS regularly (n = 48; 82.8% vs. n = 57; 98.3%, p = 0.016), change IIS every 2 to 3 days (n = 27; 46.6% vs. n = 35; 60.3%, p = 0.043), use "crisscross" rotation (n = 5; 8.8% vs. n = 12; 21.4%, p = 0.027) was observed. There were less patients reporting not having repeatable rotation manner (n = 15; 26.3% vs. n = 2; 5.4%, p = 0.009). C o n c l u s i o n s: A substantial proportion of T1DM patients on pump therapy declare that they do not follow the recommended principles of IIS use. The intervention consisting of LH assessment and retrain- ing of proper use of IIS might be effective in improving patient compliance.
正确使用胰岛素输液器(IIS)在1型糖尿病(T1DM)患者的泵治疗中起着重要作用。我们评估了接受胰岛素泵治疗的T1DM患者使用IIS的相关习惯。本研究纳入了79名T1DM患者,检查了是否存在脂肪肥大(LH),并对其进行了再培训,以便正确使用IIS。他们在研究开始时和随访时完成了一份关于IIS的标准问卷。在基线时,大多数患者宣称使用塑料套管(n = 68;86.1%),定期更换输液器(n = 65;82.3%),将输液器放置于腹壁(n = 68;86.1%)。最常见的旋转习惯是脐两侧的“曲线模式”(n = 16;20.3%)。中位数为23周(IQR 20-34)后,58例患者可进行随访。声称定期更换IIS的患者比例上升(n = 48;82.8%对n = 57;98.3%, p = 0.016),每2 ~ 3天更换一次IIS (n = 27;46.6% vs. n = 35;60.3%, p = 0.043),使用“交叉”旋转(n = 5;8.8%对n = 12;21.4%, p = 0.027)。报告没有重复旋转方式的患者较少(n = 15;26.3%对n = 2;5.4%, p = 0.009)。在接受泵治疗的T1DM患者中,有相当大比例的患者声称他们没有遵循推荐的IIS使用原则。干预包括LH评估和再培训正确使用IIS可能有效地提高患者的依从性。
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引用次数: 0
Inguinal hernia management in preterm infants: addressing current issues of interest. 腹股沟疝管理的早产儿:解决当前的问题感兴趣。
Q3 Medicine Pub Date : 2023-03-09 DOI: 10.24425/fmc.2020.136203
I. Patoulias, I. Gkalonaki, D. Patoulias
: We define as preterm any newborn born before 37 weeks of gestation. The incidence of inguinal hernia is 1–4.4% among full term neonates and older children. In preterm newborns it is significantly more often, with an incidence that raises up to 30%. In this comprehensive review of the literature we provide evidence-based answers in various questions concerning the optimal treatment of inguinal hernias in preterm neonates. Such questions include the proper time of intervention, the choice of optimal anesthesia, the necessity for contralateral investigation in case of an ipsilateral hernia, the prevention of post-operative apnea and the choice between classic and laparoscopic surgical techniques.
我们将妊娠37周前出生的新生儿定义为早产。足月新生儿和大龄儿童腹股沟疝的发生率为1-4.4%。在早产新生儿中更为常见,发病率高达30%。在这篇全面的文献综述中,我们提供了关于早产儿腹股沟疝最佳治疗的各种问题的循证答案。这些问题包括适当的干预时间、最佳麻醉的选择、同侧疝时对侧检查的必要性、术后呼吸暂停的预防以及经典手术技术和腹腔镜手术技术的选择。
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引用次数: 1
Past strong experiences determine acute cardiovascular autonomic responses to acoustic stress. 过去的强烈经历决定了对声学应激的急性心血管自主反应。
Q3 Medicine Pub Date : 2023-02-21 DOI: 10.24425/fmc.2020.136206
Michał Jurczyk, Andrzej Boryczko, A. Furgała, Adrian Poniatowski, A. Surdacki, K. Gil
BACKGROUNDStress is a major risk factor for cardiovascular (CV) disease. We hypothesized that past strong experiences might modulate acute CV autonomic responses to an unexpected acoustic stimulus. A i m: The study's aim was to compare acute CV autonomic responses to acoustic stress between students with and without a past strong experience associated with the acoustic stimulus.MATERIALS AND METHODSTwenty five healthy young volunteers - medical and non-medical students - were included in the study. CV hemodynamic parameters, heart rate (HR), and blood pressure (BP) variability were assessed for 10 min at rest and for 10 min after two different acoustic stimuli: a standard sound signal and a specific sound signal used during a practical anatomy exam (so-called "pins").RESULTSBoth sounds stimulated the autonomic nervous system. The "pins" signal caused a stronger increase in HR in medical students (69 ± 10 vs. 73 ± 13 bpm, p = 0.004) when compared to non-medical students (69 ± 6 vs. 70 ± 10, p = 0.695). Rises in diastolic BP, observed 15 seconds after sound stressors, were more pronounced after the "pins" sound than after the standard sound signal only in medical students (3.1% and 1.4% vs. 3% and 4.4%), which was also reflected by low-frequency diastolic BP variability (medical students: 6.2 ± 1.6 vs. 4.1 ± 0.8 ms2, p = 0.04; non-medical students: 6.0 ± 4.3 vs. 4.1 ± 2.6 ms2, p = 0.06).CONCLUSIONSThe "pins" sound, which medical students remembered from their anatomy practical exam, provoked greater sympathetic activity in the medical student group than in their non-medical peers. Thus, past strong experiences modulate CV autonomic responses to acute acoustic stress.
背景:应激是心血管疾病的主要危险因素。我们假设过去强烈的经历可能会调节急性CV自主神经对意外声刺激的反应。A:这项研究的目的是比较有和没有与声刺激相关的强烈经验的学生对声应激的急性CV自主反应。材料和方法25名健康的年轻志愿者——医学院和非医学院的学生——被纳入研究。静息10分钟和两种不同声刺激后10分钟评估CV血流动力学参数、心率(HR)和血压(BP)变异性:标准声信号和实际解剖检查中使用的特定声信号(所谓的“针”)。结果两种声音均刺激自主神经系统。“针”信号导致医学生心率(69±10比73±13 bpm, p = 0.004)高于非医学生(69±6比70±10,p = 0.695)。在声音刺激后15秒,医学生的舒张压升高比标准声音信号后更明显(3.1%和1.4% vs. 3%和4.4%),这也反映在低频舒张压变异性上(医学生:6.2±1.6 vs. 4.1±0.8 ms2, p = 0.04;非医学生:6.0±4.3比4.1±2.6,p = 0.06)。结论医学生在解剖学实践考试中记住的“针”声,在医学生组中引起的交感神经活动大于非医学生组。因此,过去强烈的经验调节CV对急性声应激的自主反应。
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引用次数: 0
Perioperative management of patients with gynecological cancers. 妇科肿瘤患者围手术期的处理。
Q3 Medicine Pub Date : 2022-12-29 DOI: 10.24425/fmc.2022.144080
Paweł Krawczyk, Rafał Baran, Dominika Trojnarska, Robert Jach, Janusz Andres

Oncological surgery is the primary treatment for gynecological malignancies and is inseparably linked with anesthesia. The modern approach to interdisciplinary and multidisciplinary perioperative care in gynecologic oncological patients improves the outcome. This paper presents a review of perioperative management of patients with gynecologic oncology related to enhanced recovery after surgery and cytoreductive surgery with hyperthermic intraperitoneal chemotherapy. We performed a literature search on MEDLINE, EMBASE, Google Scholar, the Cochrane Central Register of Controlled Trials, and Clinical Trials. The database search focused on selected topics related to perioperative gynecological oncology care. The authors also contributed through individual, independent literature searches.

肿瘤手术是妇科恶性肿瘤的主要治疗手段,与麻醉有着不可分割的联系。现代方法的跨学科和多学科围手术期护理妇科肿瘤患者提高了结果。本文综述了妇科肿瘤患者的围手术期管理,以提高手术后的恢复和腹腔内热化疗的细胞减少手术。我们在MEDLINE, EMBASE, Google Scholar, Cochrane Central Register of Controlled Trials和Clinical Trials上进行了文献检索。数据库搜索集中于与围手术期妇科肿瘤护理相关的选定主题。作者还通过个人的、独立的文献检索做出了贡献。
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引用次数: 0
Adapting the OSCE to the times of the COVID-19 pandemic. A look at the e-OSCE from the students' perspective. 使欧安组织适应2019冠状病毒病大流行时代。从学生的角度看欧洲安全与合作组织。
Q3 Medicine Pub Date : 2022-12-29 DOI: 10.24425/fmc.2022.144086
Natalia Skrzypek, Natalia Baster, Ian Perera, Anna Żądło, Agata Stalmach-Przygoda, Marta Szeliga, Grzegorz Cebula

Background: At the Department of Medical Education, Centre for Innovative Medical Education at Jagiellonian University Medical College, a completely remote OSCE (e-OSCE) was con- ducted for the first time using the Microsoft Teams platform. 255 test takers were tasked with presenting their communication and clinical skills in order to assess clinical reasoning. A i m: Analysis of the assessment of the OSCE adaptation to the requirements of the COVID-19 pandemic at the Department of Medical Educations in the form of the e-OSCE from the students' perspective. M e t h o d s: Discussion of the OSCE modification was carried out among 6th-year medical students and graduates undergoing validation of their foreign medical degrees. In order to assess students' opinions of the e-OSCE, we used questionnaires. The Statistica 12.0 program was used to analyse the results. R e s u l t s: According to 91.57% of respondents, the e-OSCE was well-prepared. 60% of students strongly agree and 29.47% rather agree that the order of the stations was appropriate and clear. A majority of respondents rated the e-OSCE as fair. 66.32% of respondents strongly agree and rather agree that the proportions of communication and clinical skills were appropriate. The vast majority of the participants of the exam (81.05%) had enough time for individual stations. A statistically significant (p <0.0001) correlation was found between the type of classes and preparation for the e-OSCE. For 61.05% of respondents, the Laboratory Training of Clinical Skills course was the best preparation for students taking the e-OSCE. Taking into account the stressfulness of the OSCE, only 15.96% of students found the online form more stressful than the traditional (in-person) exam. C o n c l u s i o n s: The e-OSCE in students' opinions was well-organized. Informing test-takers prior to the e-OSCE about the role of invigilators assessing individual stations should be improved. The e-OSCE has been proven to be suitable for assessing a wide range of material and validating communication and clinical skills in appropriate proportions. The e-OSCE is fair according to examinees' opinion. The study proves that even in a pandemic, it is possible to prepare an online exam without exposing examiners and examinees to the dangers posed by COVID-19.

背景:在雅盖隆大学医学院创新医学教育中心医学教育系,首次使用Microsoft Teams平台进行了一次完全远程的欧安组织(e-OSCE)。255名测试者被要求展示他们的沟通和临床技能,以评估临床推理。A i m:从学生的角度分析评估欧安组织以e-欧安组织的形式在医学教育司适应COVID-19大流行的要求。在欧安组织修订的问题上,在接受外国医学学位验证的六年级医科学生和毕业生中进行了讨论。为了评估学生对e-OSCE的意见,我们采用问卷调查的方式。采用Statistica 12.0软件对结果进行分析。调查结果显示,91.57%的受访者认为欧安组织准备充分。60%的学生表示“非常同意”,29.47%的学生表示“比较同意”。大多数答复者认为欧安组织是公平的。66.32%的受访者强烈同意和比较同意沟通和临床技能的比例是合适的。绝大多数考生(81.05%)都有足够的时间进行各站考试。p
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引用次数: 1
Higher milk consumption is not associated with fracture risk reduction: systematic review and meta-analysis. 多喝牛奶与降低骨折风险无关:系统综述和荟萃分析。
Q3 Medicine Pub Date : 2022-12-29 DOI: 10.24425/ fmc.2022.144088
Grzegorz Goncerz, Patrycja Kojm, Sylwia Skocelas, Krzysztof Więckowski, Tomasz Gallina, Paulina Pietrzyk, Sebastian Goncerz

Introduction: Osteoporosis affects over 200 million people worldwide causing nearly 9 million fractures annually, with more than half in America and Europe.

Objectives: This meta-analysis was conducted to investigate whether low milk intake is associated with an increased risk of fractures by summarizing all the available evidence.

Methods: Relevant studies were identified by searching the PubMed and EMBASE databases up to June 2020. The pooled relative risks with 95% confidence intervals were calculated.

Results: In a meta-regression analysis of 20 included studies (11 cohort and 9 case-control studies), a higher milk intake was not associated with a reduction in the total fracture risk in both sexes (OR 0.95, 95% CI: 0.84- 1.08), either in cohort (OR 0.91; 95% CI: 0.79-1.05) or case-control studies (OR 1.09; 95% CI: 0.82-1.44), as well as separately in men (OR 0.87; 95% CI: 0.71-1.07) and women (OR 0.95; 95% CI: 0.80-1.13).

Conclusion: Higher milk consumption is not associated with fracture risk reduction and should not be recommended for fracture prevention.

导言:骨质疏松症影响着全球 2 亿多人,每年造成近 900 万例骨折,其中一半以上发生在美国和欧洲:本荟萃分析旨在通过总结所有可用证据,研究牛奶摄入量低是否与骨折风险增加有关:方法:通过检索截至 2020 年 6 月的 PubMed 和 EMBASE 数据库,确定了相关研究。结果:在一项荟萃回归分析(meta-regression analysis)中,研究人员发现,牛奶与骨折的发生有关:结果:在对 20 项纳入研究(11 项队列研究和 9 项病例对照研究)进行的元回归分析中,牛奶摄入量增加与男女总骨折风险降低无关(OR 0.95,95% CI:0.84- 1.08),无论是队列研究(OR 0.91;95% CI:0.79-1.05)还是病例对照研究(OR 1.09;95% CI:0.82-1.44),以及男性(OR 0.87;95% CI:0.71-1.07)和女性(OR 0.95;95% CI:0.80-1.13)均是如此:结论:多喝牛奶与降低骨折风险无关,因此不应推荐用于预防骨折。
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引用次数: 0
Cranial diploic channels and their veins - a review of literature. 颅外交通道及其静脉——文献综述。
Q3 Medicine Pub Date : 2022-12-29 DOI: 10.24425/fmc.2022.144085
Janusz Skrzat, Michał Zarzecki

The current paper is a review of the results attained in the past and current anatomical studies, aimed at understanding the variability and function of the diploic venous system of the human skull. The diploic veins can serve as transit for infections from the scalp to the structures contained within the cranial cavity via the emissary veins, due to their interconnections with the pericranial veins, meningeal veins and dural sinuses. Thereby this clinical aspect has also been discussed.

本文综述了在过去和现在的解剖学研究中所取得的结果,旨在了解人类颅骨的锁骨静脉系统的变异性和功能。由于复静脉与颅周静脉、脑膜静脉和硬脑膜窦相互连接,故复静脉可作为感染从头皮到颅腔内结构的中转通道。因此,这个临床方面也进行了讨论。
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引用次数: 0
Temporomandibular disorders and their impact on the development of the overloading changes within temporomandibular joints. 颞下颌关节疾病及其对颞下颌关节超载变化发展的影响。
Q3 Medicine Pub Date : 2022-12-29 DOI: 10.24425/fmc.2022.144082
Małgorzata Pihut, Andrzej Gala, Małgorzata Kulesa-Mrowiecka

TMD is a disease within the masticatory system that increases its reach among the society every year in the third and fourth decade of life. The etiology of TMD is complex and it is often difficult to establish the cause in a specific case. The a i m of the study was to determine the impact of TMD on pathomorphological changes within the temporomandibular joints, evaluated in USG examinations and evaluation the assessment of differences in the number of pathological changes between various forms of TMD.

Material and methods: The study material included a group of 386 patients, both sexes, aged 20 to 46 years, who came for prosthetic treatment due to symptoms of TMD. Ultrasound examination of the temporomandibular joints supplemented the clinical diagnosis of TMD in all the subjects. Axis I of the DC/TMD were used.

Results: Group I included 116 women and 89 men, group II consisted of 102 women and 79 men. Pathological morphological changes in the temporomandibular joints were found in all the examined patients. The changes in soft tissue structures were significantly increased in group II, but numerous pathomorphological changes were also present in the group of patients with the muscle form of TMD.

Conclusion: The results of the conducted studies with the use of USG temporomandibular joints revealed numerous pathomorphological changes within the temporomandibular joints. This indicates the usefulness of the USG examination in additional diagnostic tests in the group of patients with TMD.

TMD是一种发生在咀嚼系统内的疾病,在生命的第三和第四个十年中,其在社会中的发病率每年都在增加。TMD的病因是复杂的,往往很难确定一个具体的情况下的原因。本研究的目的是确定TMD对颞下颌关节内病理形态学改变的影响,在USG检查中进行评估,并评估不同形式TMD之间病理改变数量的差异。材料和方法:研究材料包括一组386例患者,男女皆有,年龄20 - 46岁,因TMD症状前来接受假体治疗。所有受试者均以颞下颌关节超声检查补充TMD的临床诊断。使用DC/TMD的I轴。结果:第一组女性116例,男性89例;第二组女性102例,男性79例。所有患者的颞下颌关节均有病理形态学改变。软组织结构的改变在II组明显增加,但肌肉型TMD患者组也出现了许多病理形态学改变。结论:使用USG颞下颌关节进行的研究结果显示了颞下颌关节内的许多病理形态学变化。这表明USG检查在TMD患者组的附加诊断检查中是有用的。
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引用次数: 0
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Folia medica Cracoviensia
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